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GPI Anchor Biosynthesis Report: AAK52677.1 (GPI7 family, Yarrowia lipolytica)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 
         (860 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Results of PSI-Blast iteration 6

Distribution of 61 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)
Sequences producing significant alignments: (bits) Value
gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarr... 882 0.0
ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class ... 730 0.0
ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class ... 711 0.0
ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involv... 643 0.0
dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N sh... 633 e-180
gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinosito... 627 e-178
ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; ... 606 e-172
sp|Q09782|YA93_SCHPO HYPOTHETICAL 85.7 KD PROTEIN C13G6.03 IN CH... 606 e-172
pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragme... 602 e-170
pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast (... 592 e-167
pir||T40715 hypothetical protein SPBC839.08c - fission yeast (S... 579 e-164
gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melano... 565 e-159
ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan... 554 e-156
ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]... 544 e-153
gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melano... 542 e-153
ref|NP_495820.1| (NM_063419) Yeast YJ10 like [Caenorhabditis ele... 487 e-136
gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caeno... 485 e-136
gb|AAF54657.1| (AE003692) CG6790 gene product [Drosophila melano... 453 e-126
dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [M... 423 e-117
ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) ... 422 e-116
ref|XP_082200.1| (XM_082200) CG6790 [Drosophila melanogaster] 416 e-115
ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class ... 371 e-101
ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans] 352 1e-95
gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melano... 344 5e-93
ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thalia... 332 1e-89
dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:13516... 321 2e-86
gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melan... 304 4e-81
ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thalia... 284 4e-75
gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophos... 256 2e-66
dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like prote... 249 1e-64
ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like pr... 249 2e-64
ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like p... 245 3e-63
ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like p... 239 2e-61
pir||T33724 hypothetical protein - Zymomonas mobilis >gi|3089614... 237 7e-61
pir||T03293 nucleotide pyrophosphatase homolog - rice >gi|818849... 232 2e-59
ref|NP_005012.1| (NM_005021) ectonucleotide pyrophosphatase/phos... 228 3e-58
dbj|BAA06333.1| (D30649) phosphodiesterase I [Rattus norvegicus] 226 1e-57
ref|NP_062243.1| (NM_019370) alkaline phosphodiesterase [Rattus ... 226 1e-57
gb|AAB61536.1| (U78788) alkaline phosphodiesterase [Rattus norve... 225 2e-57
pir||T40657 probable phophodiesterase-nucleotide pyrophosp hatas... 224 4e-57
ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo ... 222 2e-56
pir||A57080 cell surface antigen RB13-6 - rat >gi|806379|emb|CAA... 220 7e-56
dbj|BAA02053.1| (D12485) The first in-frame ATG codon is located... 219 1e-55
pir||A39216 plasma cell membrane glycoprotein PC-1 - human >gi|7... 219 2e-55
ref|NP_006199.1| (NM_006208) ectonucleotide pyrophosphatase/phos... 217 8e-55
emb|CAB99365.1| (AL117378) dJ131F15.2 (phosphodiesterase I/nucle... 216 2e-54
ref|NP_116023.1| (NM_032634) hypothetical protein MGC3079 [Homo ... 213 9e-54
ref|NP_299876.1| (NC_002488) phosphodiesterase-nucleotide pyroph... 209 1e-52
ref|NP_067547.1| (NM_021572) ectonucleotide pyrophosphatase/phos... 197 6e-49
Alignments
>gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarrowia lipolytica]
          Length = 860

 Score =  882 bits (2257), Expect = 0.0
 Identities = 860/860 (100%), Positives = 860/860 (100%)

Query: 1   MLWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFR 60
           MLWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFR
Sbjct: 1   MLWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFR 60

Query: 61  SDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAE 120
           SDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAE
Sbjct: 61  SDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAE 120

Query: 121 SDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASFFVSDYTEVDNN 180
           SDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASFFVSDYTEVDNN
Sbjct: 121 SDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASFFVSDYTEVDNN 180

Query: 181 VTRHIDTQLDQKTEWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDD 240
           VTRHIDTQLDQKTEWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDD
Sbjct: 181 VTRHIDTQLDQKTEWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDD 240

Query: 241 TVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFETAQLTETAETSPLPWTDTYKYHS 300
           TVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFETAQLTETAETSPLPWTDTYKYHS
Sbjct: 241 TVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFETAQLTETAETSPLPWTDTYKYHS 300

Query: 301 RMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSPEDQLNVLKNNADQMVQILQGQAS 360
           RMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSPEDQLNVLKNNADQMVQILQGQAS
Sbjct: 301 RMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSPEDQLNVLKNNADQMVQILQGQAS 360

Query: 361 RESDAKEVYELYDTLNSNPSVKDYYNFLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTIL 420
           RESDAKEVYELYDTLNSNPSVKDYYNFLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTIL
Sbjct: 361 RESDAKEVYELYDTLNSNPSVKDYYNFLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTIL 420

Query: 421 ALTVFSALTLAVQGLKRLYLIILLVYFISVFGSSTVEEEHQIWYWITSGWMAFLYISGSR 480
           ALTVFSALTLAVQGLKRLYLIILLVYFISVFGSSTVEEEHQIWYWITSGWMAFLYISGSR
Sbjct: 421 ALTVFSALTLAVQGLKRLYLIILLVYFISVFGSSTVEEEHQIWYWITSGWMAFLYISGSR 480

Query: 481 NKFGDGFNWMFVQVFVRMMISWNQTGQKFTKKDDIVTWLSKDGNQPSLWILILVTYGVAF 540
           NKFGDGFNWMFVQVFVRMMISWNQTGQKFTKKDDIVTWLSKDGNQPSLWILILVTYGVAF
Sbjct: 481 NKFGDGFNWMFVQVFVRMMISWNQTGQKFTKKDDIVTWLSKDGNQPSLWILILVTYGVAF 540

Query: 541 NKVWRYGFSKVESKLAFLLTLITTFASVGFKITQAWEAGEVVPAPLLYLMGLPGTLNEVN 600
           NKVWRYGFSKVESKLAFLLTLITTFASVGFKITQAWEAGEVVPAPLLYLMGLPGTLNEVN
Sbjct: 541 NKVWRYGFSKVESKLAFLLTLITTFASVGFKITQAWEAGEVVPAPLLYLMGLPGTLNEVN 600

Query: 601 ARMAGLARFAFSTIAAGSLYRVLSLAGTDKVNLIRDLHAFLTLFLITQSRIQNIPLFMVY 660
           ARMAGLARFAFSTIAAGSLYRVLSLAGTDKVNLIRDLHAFLTLFLITQSRIQNIPLFMVY
Sbjct: 601 ARMAGLARFAFSTIAAGSLYRVLSLAGTDKVNLIRDLHAFLTLFLITQSRIQNIPLFMVY 660

Query: 661 YFLEIFLRKATNRSFIFSSRDIYQTEALFQKLVLVLSVSTLLLEQVSFFSMGNSNSMASI 720
           YFLEIFLRKATNRSFIFSSRDIYQTEALFQKLVLVLSVSTLLLEQVSFFSMGNSNSMASI
Sbjct: 661 YFLEIFLRKATNRSFIFSSRDIYQTEALFQKLVLVLSVSTLLLEQVSFFSMGNSNSMASI 720

Query: 721 DLSNAYNGVTLYQIEFVGVLTFVSNWIGPLYWSTAGLSFLLEDHVRNAIFAKIAEKNNDV 780
           DLSNAYNGVTLYQIEFVGVLTFVSNWIGPLYWSTAGLSFLLEDHVRNAIFAKIAEKNNDV
Sbjct: 721 DLSNAYNGVTLYQIEFVGVLTFVSNWIGPLYWSTAGLSFLLEDHVRNAIFAKIAEKNNDV 780

Query: 781 KLTTKLVQQALTLRVYVVLAFSSVAISAVMITCFFLREHLFIWTVFSPKLLYQFVWTVLQ 840
           KLTTKLVQQALTLRVYVVLAFSSVAISAVMITCFFLREHLFIWTVFSPKLLYQFVWTVLQ
Sbjct: 781 KLTTKLVQQALTLRVYVVLAFSSVAISAVMITCFFLREHLFIWTVFSPKLLYQFVWTVLQ 840

Query: 841 FALVDVILSSIFVVLVYRSV 860
           FALVDVILSSIFVVLVYRSV
Sbjct: 841 FALVDVILSSIFVVLVYRSV 860
>ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class N [Mus musculus]
 dbj|BAA82619.1| (AB030279) phosphatidylinositolglycan class N [Mus musculus]
          Length = 931

 Score =  730 bits (1867), Expect = 0.0
 Identities = 149/939 (15%), Positives = 305/939 (31%), Gaps = 162/939 (17%)

Query: 1   MLWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFR 60
           +L+    L +  V       + F         L+ G T        P ++ ++ V D  R
Sbjct: 2   LLFFALGLLIHFVFFVSIFDIYFTS------PLVHGMTPQFTPLPPPAKRLVLFVADGLR 55

Query: 61  SDFAFS----DQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVL 116
           +D  +       S  P +   I   G+    +H+  PT + P    L  G   +    V 
Sbjct: 56  ADTLYELDEDGNSRAPFIRNVIMHEGSWG-VSHTRVPTESRPGHVALIAGFYED----VS 110

Query: 117 NIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFP-GMFDDCEGTAS------- 168
            +A+    + +   DS   ++         +G    + +F  G   D   T S       
Sbjct: 111 AVAKGWKENPV-EFDSLFNESKYTW----SWGSPDILPMFAKGASGDHVYTYSYDAQRED 165

Query: 169 FFVSDYTEVDNNVTRHIDTQLDQK-----------TEWDVLILHYLGLDHIGHKTGPESP 217
           F   D T++D  V   +    D              E  V  LH LG+D  GH   P S 
Sbjct: 166 FGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSR 225

Query: 218 FMPAKQKEMDDIFDKLYNSC------DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVF 271
                 K++DD   ++ +        D  T  I   DHGM + G+HG     ET    V 
Sbjct: 226 EYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVT 285

Query: 272 ASP--KFETAQLTETAETSPL-PWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLV 328
                KF      +  +   L  W         ++Q D+ P + +L+G+  P N++G+L 
Sbjct: 286 WGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILP 345

Query: 329 SQMLGLWSPEDQLNVLKNNADQMVQILQGQASRESDAK--EVYELYDTLNSNPSVKDYYN 386
              L       +   +  NA Q+++  + + +++ +A    ++  +  L+ +  +    +
Sbjct: 346 VGYLNNTGLF-KAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQL----D 400

Query: 387 FLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTILALTVFSALTLAVQGLKRLYLIILLV- 445
            L +A+SY+         ++++      +   +  L+ +        G+      +  + 
Sbjct: 401 ILRKARSYIKQEK----FDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMS 456

Query: 446 ---YFISVFGSSTV-------EEEH--QIWYWITSGWMAFLYISGSRNKFGDGFNWMFVQ 493
                I    S+         ++ H   ++ +I +G +   ++            W +  
Sbjct: 457 YTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQAC------PWTYYV 510

Query: 494 VFVRMMISWNQTGQKFTKKDDIVTWLSKDGNQPSLWILILVTYGV---AFNKVWRYGFSK 550
             +  +  W    ++     D+V  L        +  L++ T G+     +  +RY  + 
Sbjct: 511 YCLLPVPIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTA 570

Query: 551 VESKLAFLL--TLITTFASVGFKITQAWEAGEVVPAPLLYLMGLPGTLNEVNAR------ 602
                A     T + T A + F ++ A+ +  +   PL+ ++G    L+ V         
Sbjct: 571 GLIVFAGWPFLTQLWTRAKITF-LSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLVLL 629

Query: 603 -------------------------MAGLARFAFSTIAAGSLYRVLSLAGT-------DK 630
                                    +  L+      +   + + +L   G          
Sbjct: 630 LSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQIVSW 689

Query: 631 VNLIRDLHAFLTLFLITQSRIQNIPLFMV---------YYFLEIFLRKATNRSFIFSSRD 681
             L   L A L        R+ +I L ++         Y  L   +       +I   ++
Sbjct: 690 ATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQE 749

Query: 682 IYQTEALFQKLVL----------------------VLSVSTLLLEQVSFFSMGNSNSMAS 719
             Q   +  K  L                        +   +     +FF  GN  S+ S
Sbjct: 750 TLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLVFFLLTAFFGTGNIASINS 809

Query: 720 IDLSNAYNGVTLYQIEFVGVLTFVSNWIGPLY-WSTAGLSFLLEDHVRNAIFAKIAEKNN 778
            DL++ Y  +T++    +G L      I  +          +        +F  +   ++
Sbjct: 810 FDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQITTQLSSKGLFLVVLIISD 869

Query: 779 DVKLT--------TKLVQQALTLRVYVVLAFSSVAISAV 809
            + L            +    ++  YV++   ++ +  +
Sbjct: 870 IMALHFFFLVKDSGSWLDIGTSISHYVIVMSMTIFLVFL 908
>ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class N; endoplasmic
           reticulum membrane protein [Homo sapiens]
 gb|AAD11432.1| (AF109219) Mcd4p homolog [Homo sapiens]
          Length = 931

 Score =  711 bits (1816), Expect = 0.0
 Identities = 148/934 (15%), Positives = 310/934 (32%), Gaps = 152/934 (16%)

Query: 1   MLWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFR 60
           +L+    L +  V       + F         L+ G T        P ++ ++ V D  R
Sbjct: 2   LLFFTLGLLIHFVFFASIFDIYFTS------PLVHGMTPQFTPLPPPARRLVLFVADGLR 55

Query: 61  SDFAFS----DQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVL 116
           +D  +       S  P +   I   G+    +H+  PT + P    L  G   +    V 
Sbjct: 56  ADALYELDENGNSRAPFIRNIIMHEGSWG-ISHTRVPTESRPGHVALIAGFYED----VS 110

Query: 117 NIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFP-GMFDDCEGTAS------- 168
            +A+    + +   DS   ++         +G    + +F  G   D   T S       
Sbjct: 111 AVAKGWKENPV-EFDSLFNESKYTW----SWGSPDILPMFAKGASGDHVYTYSYDAKRED 165

Query: 169 FFVSDYTEVDNNVTRHIDTQ---------LDQK--TEWDVLILHYLGLDHIGHKTGPESP 217
           F   D T++D  V  ++            L  K   E  V  LH LG+D  GH   P S 
Sbjct: 166 FGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSR 225

Query: 218 FMPAKQKEMDDIFDKLYNSC------DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVF 271
                 K++DD   ++ +        D  T  I   DHGM + G+HG     ET   +V 
Sbjct: 226 DYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVT 285

Query: 272 ASP--KFETAQLTETAETSPL-PWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLV 328
                K+      +  + + L  W         ++Q D+ P +T+L+G+  P N++G+L 
Sbjct: 286 WGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILP 345

Query: 329 SQMLGLWSPEDQLNVLKNNADQMVQILQGQASRESDAK--EVYELYDTLNSNPSVKDYYN 386
              L       +   +  NA Q+++  + + +++ +     ++  +  L+ +      +N
Sbjct: 346 VDYLNNT-DLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQ----FN 400

Query: 387 FLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTILALTVFSALTLAVQGLKRLYLIILLV- 445
            L +A+SY+ H       ++++      +   +  L+ +        G+  +   +  + 
Sbjct: 401 ILRKARSYIKHRK----FDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWIS 456

Query: 446 ---YFISVFGSSTV----EEEHQIWYWITSGWMAFLYISGSRNKFGDGFNWMFVQVFVRM 498
                I    S+ +    +E  +  + +   ++A   +            W +    +  
Sbjct: 457 YASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLI-QACPWTYYVYGLLP 515

Query: 499 MISWNQTGQKFTKKDDIVTWLSKDGNQPSLWILILVTYGV---AFNKVWRYGFSKVESKL 555
           +  W    ++F    D+V  +        +  L+  T G+     +  +RY  +   +  
Sbjct: 516 LPIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAF 575

Query: 556 AFLL--TLITTFASVGFKITQAWEAGEVVPAPLLYLMGLPGTLNEVNAR----------- 602
           A     T + T A +   ++  + +  +   PL+ ++G    ++ V              
Sbjct: 576 AAWPFLTRLWTRAKMT-SLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAGLLVLLLSLCV 634

Query: 603 --------------------MAGLARFAFSTIAAGSLYRVLSLAGT-------DKVNLIR 635
                               +  L+      +   +   +L   G            L  
Sbjct: 635 VTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQIISWATLAS 694

Query: 636 DLHAFLTLFLITQSRIQNIPLFMV---------YYFLEIFLRKATNRSFIFSSRDIYQTE 686
            L   L    +   R+ +I L ++         Y  L   +       +I   ++  Q  
Sbjct: 695 SLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIEQETLQQS 754

Query: 687 -------------------ALFQKLVL---VLSVSTLLLEQVSFFSMGNSNSMASIDLSN 724
                                F++L L     +   +     +FF  GN  S+ S DL++
Sbjct: 755 GVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIASINSFDLAS 814

Query: 725 AYNGVTLYQIEFVGVLTFVSNWIGPLY-WSTAGLSFLLEDHVRNAIFAKIAEKNNDVKLT 783
            Y  +T++    +G L      I  +          L       ++F  +   ++ + L 
Sbjct: 815 VYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLVISDIMALH 874

Query: 784 --------TKLVQQALTLRVYVVLAFSSVAISAV 809
                      +    ++  YV++   ++ +  +
Sbjct: 875 FFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFL 908
>ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involved in the attachment
           of glycosylphosphatidylinositol (GPI) anchors to
           proteins.; Las21p [Saccharomyces cerevisiae]
 sp|P40367|YJG2_YEAST HYPOTHETICAL 94.9 KD PROTEIN IN MRPL8-NUP82 INTERGENIC REGION
 pir||S50810 probable membrane protein YJL062w - yeast (Saccharomyces
           cerevisiae)
 emb|CAA84061.1| (Z34288) HRC830 [Saccharomyces cerevisiae]
 emb|CAA89353.1| (Z49337) ORF YJL062w [Saccharomyces cerevisiae]
          Length = 830

 Score =  643 bits (1642), Expect = 0.0
 Identities = 296/862 (34%), Positives = 449/862 (51%), Gaps = 84/862 (9%)

Query: 16  QLAAVLLFARGFLPSRVLLPGYTES------RVSTEAPFQKAIIMVVDAFRSDFAFSDQ- 68
           QL A+LLF   F P +++L G ++        +  + PFQK + +++DA RSDF F  Q 
Sbjct: 13  QLLAILLFIFAFFPRKIVLTGISKQDPDQDRDLQRDRPFQKLVFVIIDALRSDFLFDSQI 72

Query: 69  SNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAESDNSSTLA 128
           S+   +H+ +N+G A  +T+ + PPTVTLPR+K +TTGSTP+F+D +LN+A+  +S+ L+
Sbjct: 73  SHFNNVHQWLNTGEAWGYTSFANPPTVTLPRLKSITTGSTPSFIDLLLNVAQDIDSNDLS 132

Query: 129 NQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCE-GTASFFVSDYTEVDNNVTRHIDT 187
             DSWL Q  +    I   GDDTW+KLFP  + D    T SFFVSD+T+VDNNVTR++  
Sbjct: 133 EHDSWLQQFIQHNNTIRFMGDDTWLKLFPQQWFDFADPTHSFFVSDFTQVDNNVTRNLPG 192

Query: 188 QLDQK-TEWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIFDKLYNSC-----DDDT 241
           +L Q+  +WDV ILHYLGLDHIGHK GP S FM AK +EMD I   +Y+       DDDT
Sbjct: 193 KLFQEWAQWDVAILHYLGLDHIGHKDGPHSKFMAAKHQEMDSILKSIYDEVLEHEDDDDT 252

Query: 242 VLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFETAQLTETAETSPLPWT----DTYK 297
           ++ +LGDHGMNE+GNHGGSSAGETSA ++F SPK       E+     LP        ++
Sbjct: 253 LICVLGDHGMNELGNHGGSSAGETSAGLLFLSPKLAQFARPESQVNYTLPINASPDWNFQ 312

Query: 298 YHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSPEDQLNVLKNNADQMVQILQG 357
           Y   + Q D+VPT+ AL G+  P N++G+++   L L     +L  +K N   + ++   
Sbjct: 313 YLETVQQIDIVPTIAALFGMPIPMNSVGIIIPDFLQLLPN--KLASMKENFMHLWKL--- 367

Query: 358 QASRESDAKEVYELYDTLNSNPSVKDYYNFLYEAQSYLTHASSNYNTNDMLGGIGLGLLS 417
                SD      L D      + +D Y  +Y  Q  LT +++NYN   +       L+ 
Sbjct: 368 -----SDHHGEVALDDF-----TAEDIYTKMYTIQETLTKSATNYNYPLLTLAFVGFLII 417

Query: 418 TILALTVFSALT----LAVQGLKRLYLIILLVYFISVFGSSTVEEEHQIWYWITSGWMAF 473
           TI+A+ V    +      ++      L++ ++  +S F SS +EEEHQ+W+WI + + A 
Sbjct: 418 TIIAIYVLLRYSGPDFWQLRVSSLSVLLVSIILGVSTFASSFIEEEHQLWWWIVTAFSA- 476

Query: 474 LYISGSRNKFGDGFNWMFVQVFVRMMISWNQTGQKFTKKDDIVTWLSKDGNQPSLWILIL 533
           + +   R        W  +   VR +  WN +GQKF   + +   L++  N    W L +
Sbjct: 477 VPLFVYRLNVLIIVRWFIMMACVRSIKFWNNSGQKFIYSNVMSNLLNQ--NPSWKWCLNM 534

Query: 534 VTYGVAFNKVWRYGFSKVESKLAFLLTLITTFASVGFKITQAWEAGEVVPAPLLYLMGLP 593
           +T+ V          S     L F++T I       +KI+     G     P L++  L 
Sbjct: 535 LTFLVLI------MASAGFQVLHFIVTTILVGLCFTYKISWEIVNGNQAEIP-LFMHDLL 587

Query: 594 GTLN--EVNARMAGLARFAFSTIAAGSLYRVLS--LAGTDKVNLIRDLHAFLTLFLITQS 649
             ++     + +  LAR  F   A   + R++   L   +K  LI+D+  ++T+ L+ Q+
Sbjct: 588 AKIDFAPTESNLIVLARVFFQAWAIVVISRLVLTKLKVLNKNYLIKDMKVYITILLMFQT 647

Query: 650 RIQNIPLFMVYYFLEIFL---RKATNRSFIFSSRDIYQTEALFQKLVLVLSVSTLLLEQV 706
             QNI  F+V+  LE  +    +    + + S+  IY     F  LV      +L+L+  
Sbjct: 648 SSQNIGQFLVFQILESQIFYFFQNIPTASLTSTSKIY-----FSNLV------SLILQNF 696

Query: 707 SFFSMGNSNSMASIDLSNAYNGVTL-YQIEFVGVLTFVSNWIGPLYWSTAGLSFLLEDHV 765
           +FF  G +NS+++IDL NAY+GV+  Y I  VG+L  V+N+   +YWS    S       
Sbjct: 697 TFFQFGGTNSISTIDLGNAYHGVSSDYNIYVVGILMSVANFAPAIYWSMLPWSI------ 750

Query: 766 RNAIFAKIAEKNNDVKLTTKLVQQALTLRVYVVLAFSSVAISAVMITCFFLREHLFIWTV 825
               +A I      VKL T +  +      + +        + +M  C  LR HLFIW+V
Sbjct: 751 ---NYASIPA---QVKLQTFIRSKLPAFTYHCIFG------TCLMTACVVLRFHLFIWSV 798

Query: 826 FSPKLLYQFVWTVLQFALVDVI 847
           FSPKL Y   W  +   L   +
Sbjct: 799 FSPKLCYFLGWNFVMGLLNGWL 820
>dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N short form [Mus
           musculus]
          Length = 798

 Score =  633 bits (1617), Expect = e-180
 Identities = 132/793 (16%), Positives = 262/793 (32%), Gaps = 131/793 (16%)

Query: 1   MLWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFR 60
           +L+    L +  V       + F         L+ G T        P ++ ++ V D  R
Sbjct: 2   LLFFALGLLIHFVFFVSIFDIYFTS------PLVHGMTPQFTPLPPPAKRLVLFVADGLR 55

Query: 61  SDFAFS----DQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVL 116
           +D  +       S  P +   I   G+    +H+  PT + P    L  G   +    V 
Sbjct: 56  ADTLYELDEDGNSRAPFIRNVIMHEGSWG-VSHTRVPTESRPGHVALIAGFYED----VS 110

Query: 117 NIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFP-GMFDDCEGTAS------- 168
            +A+    + +   DS   ++         +G    + +F  G   D   T S       
Sbjct: 111 AVAKGWKENPV-EFDSLFNESKYTW----SWGSPDILPMFAKGASGDHVYTYSYDAQRED 165

Query: 169 FFVSDYTEVDNNVTRHIDTQLDQK-----------TEWDVLILHYLGLDHIGHKTGPESP 217
           F   D T++D  V   +    D              E  V  LH LG+D  GH   P S 
Sbjct: 166 FGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSR 225

Query: 218 FMPAKQKEMDDIFDKLYNSC------DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVF 271
                 K++DD   ++ +        D  T  I   DHGM + G+HG     ET    V 
Sbjct: 226 EYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVT 285

Query: 272 ASP--KFETAQLTETAETSPL-PWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLV 328
                KF      +  +   L  W         ++Q D+ P + +L+G+  P N++G+L 
Sbjct: 286 WGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILP 345

Query: 329 SQMLGLWSPEDQLNVLKNNADQMVQILQGQASRESDAK--EVYELYDTLNSNPSVKDYYN 386
              L       +   +  NA Q+++  + + +++ +A    ++  +  L+ +  +    +
Sbjct: 346 VGYLNNTGLF-KAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQL----D 400

Query: 387 FLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTILALTVFSALTLAVQGLKRLYLIILLV- 445
            L +A+SY+         ++++      +   +  L+ +        G+      +  + 
Sbjct: 401 ILRKARSYIKQEK----FDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMS 456

Query: 446 ---YFISVFGSSTV-------EEEH--QIWYWITSGWMAFLYISGSRNKFGDGFNWMFVQ 493
                I    S+         ++ H   ++ +I +G +   ++            W +  
Sbjct: 457 YTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQAC------PWTYYV 510

Query: 494 VFVRMMISWNQTGQKFTKKDDIVTWLSKDGNQPSLWILILVTYGV---AFNKVWRYGFSK 550
             +  +  W    ++     D+V  L        +  L++ T G+     +  +RY  + 
Sbjct: 511 YCLLPVPIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTA 570

Query: 551 VESKLAFLL--TLITTFASVGFKITQAWEAGEVVPAPLLYLMGLPGTLNEVNAR------ 602
                A     T + T A + F ++ A+ +  +   PL+ ++G    L+ V         
Sbjct: 571 GLIVFAGWPFLTQLWTRAKITF-LSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLVLL 629

Query: 603 -------------------------MAGLARFAFSTIAAGSLYRVLSLAGT-------DK 630
                                    +  L+      +   + + +L   G          
Sbjct: 630 LSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQIVSW 689

Query: 631 VNLIRDLHAFLTLFLITQSRIQNIPLFMV---------YYFLEIFLRKATNRSFIFSSRD 681
             L   L A L        R+ +I L ++         Y  L   +       +I   ++
Sbjct: 690 ATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQE 749

Query: 682 IYQTEALFQKLVL 694
             Q   +  K  L
Sbjct: 750 TLQQPGVSCKQKL 762
>gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinositol glycan, class N [Mus
           musculus]
          Length = 826

 Score =  627 bits (1601), Expect = e-178
 Identities = 132/793 (16%), Positives = 262/793 (32%), Gaps = 131/793 (16%)

Query: 1   MLWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFR 60
           +L+    L +  V       + F         L+ G T        P ++ ++ V D  R
Sbjct: 2   LLFFALGLLIHFVFFASIFDIYFTS------PLVHGMTPQFTPLPPPAKRLVLFVADGLR 55

Query: 61  SDFAFS----DQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVL 116
           +D  +       S  P +   I   G+    +H+  PT + P    L  G   +    V 
Sbjct: 56  ADTLYELDEDGNSRAPFIRNVIIHEGSWG-VSHTRVPTESRPGHVALIAGFYED----VS 110

Query: 117 NIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFP-GMFDDCEGTAS------- 168
            +A+    + +   DS   ++         +G    + +F  G   D   T S       
Sbjct: 111 AVAKGWKENPV-EFDSLFNESKYTW----SWGSPDILPMFAKGASGDHVYTYSYDAQRED 165

Query: 169 FFVSDYTEVDNNVTRHIDTQLDQK-----------TEWDVLILHYLGLDHIGHKTGPESP 217
           F   D T++D  V   +    D              E  V  LH LG+D  GH   P S 
Sbjct: 166 FGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSR 225

Query: 218 FMPAKQKEMDDIFDKLYNSC------DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVF 271
                 K++DD   ++ +        D  T  I   DHGM + G+HG     ET    V 
Sbjct: 226 EYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVT 285

Query: 272 ASP--KFETAQLTETAETSPL-PWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLV 328
                KF      +  +   L  W         ++Q D+ P + +L+G+  P N++G+L 
Sbjct: 286 WGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILP 345

Query: 329 SQMLGLWSPEDQLNVLKNNADQMVQILQGQASRESDAK--EVYELYDTLNSNPSVKDYYN 386
              L       +   +  NA Q+++  + + +++ +A    ++  +  L+ +  +    +
Sbjct: 346 VGYLNNTGLF-KAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQL----D 400

Query: 387 FLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTILALTVFSALTLAVQGLKRLYLIILLV- 445
            L +A+SY+         ++++      +   +  L+ +        G+      +  + 
Sbjct: 401 ILRKARSYIKQEK----FDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMS 456

Query: 446 ---YFISVFGSSTV-------EEEH--QIWYWITSGWMAFLYISGSRNKFGDGFNWMFVQ 493
                I    S+         ++ H   ++ +I +G +   ++            W +  
Sbjct: 457 YTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQAC------PWTYYV 510

Query: 494 VFVRMMISWNQTGQKFTKKDDIVTWLSKDGNQPSLWILILVTYGV---AFNKVWRYGFSK 550
             +  +  W    ++     D+V  L        +  L++ T G+     +  +RY  + 
Sbjct: 511 YCLLPVPIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTA 570

Query: 551 VESKLAFLL--TLITTFASVGFKITQAWEAGEVVPAPLLYLMGLPGTLNEVNAR------ 602
                A     T + T A + F ++ A+ +  +   PL+ ++G    L+ V         
Sbjct: 571 GLIVFAGWPFLTQLWTRAKITF-LSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLVLL 629

Query: 603 -------------------------MAGLARFAFSTIAAGSLYRVLSLAGT-------DK 630
                                    +  L+      +   + + +L   G          
Sbjct: 630 LSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQIVSW 689

Query: 631 VNLIRDLHAFLTLFLITQSRIQNIPLFMV---------YYFLEIFLRKATNRSFIFSSRD 681
             L   L A L        R+ +I L ++         Y  L   +       +I   ++
Sbjct: 690 ATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQE 749

Query: 682 IYQTEALFQKLVL 694
             Q   +  K  L
Sbjct: 750 TLQQPGVSCKQKL 762
>ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; Mcd4p [Saccharomyces
           cerevisiae]
 sp|P36051|YKQ5_YEAST HYPOTHETICAL 105.7 KD PROTEIN IN TPK3-PIR1 INTERGENIC REGION
 pir||S37786 hypothetical protein YKL165c - yeast (Saccharomyces cerevisiae)
 emb|CAA81489.1| (Z26877) unknown [Saccharomyces cerevisiae]
 emb|CAA82007.1| (Z28165) ORF YKL165c [Saccharomyces cerevisiae]
 prf||2118404A ORF [Saccharomyces cerevisiae]
          Length = 919

 Score =  606 bits (1548), Expect = e-172
 Identities = 167/920 (18%), Positives = 317/920 (34%), Gaps = 132/920 (14%)

Query: 2   LW-KRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFR 60
           +W K  T  + + VL     L           L+ G +  + +   P ++  ++V D  R
Sbjct: 1   MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLR 60

Query: 61  SDFAFSDQSN---------CPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNF 111
           +D  F   ++          P +   + +       +H+  PT + P    +  G   + 
Sbjct: 61  ADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYG-ISHTRMPTESRPGHVAMIAGFYED- 118

Query: 112 LDAVLNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASFFV 171
              V  + +   S+ + N DS+  Q++      + FG    + +F     D     ++  
Sbjct: 119 ---VSAVTKGWKSNPV-NFDSFFNQSTH----TYSFGSPDILPMFKDGASDPNKVDTWMY 170

Query: 172 ----SDYTE----VDNNVTRHID---------TQLDQKTEWD--VLILHYLGLDHIGHKT 212
                D+T+    +D  V RH+D         + LD +   D  V  LH LG D  GH  
Sbjct: 171 DHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSY 230

Query: 213 GPESPFMPAKQKEMDDIFDKLYNSC-----DDDTVLILLGDHGMNEVGNHGGSSAGETSA 267
            P S       K +DD    L +       DD T  I   DHGM+  G+HG      T  
Sbjct: 231 RPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRT 290

Query: 268 AMVFASPKF--ETAQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLG 325
            +V                ++     W  +    + + Q D+   ++ L+G+N PKN++G
Sbjct: 291 PLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVG 350

Query: 326 VLVSQMLGLWSPEDQLNVLKNNADQMVQILQGQASRESDAKEVYELY---DTLNSNPSVK 382
            L    +      D+L  L NNA  +++    +     D++  Y+ Y      + +  ++
Sbjct: 351 ELPIAYIDGKE-SDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLE 409

Query: 383 DYYNFLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTILALTVFSALTLAVQGLKRLYLII 442
           +    +            NY   + +      +  T+  L   +            +  +
Sbjct: 410 EIETLIQRI-----SEGENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFV 464

Query: 443 LLVYF-ISVFGSSTVEEEHQIWYWITSGWMAFLYISGSRNKFGDGF----NWMFVQVFVR 497
             ++F   +F  S +  E+ I     S     ++ S         F     + F    + 
Sbjct: 465 GWIFFSFIIFLKSFI-LENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLF 523

Query: 498 MMISWNQTGQKFTKKDDIVTWLSKDGNQPSLWILILVTY-----GVAFNKVWRYGFSKVE 552
            +  W+      +     +    K G  P   +LI ++      G+ +    R+ F+ + 
Sbjct: 524 PLYFWSYIFTNRSVLRSGIKEFFK-GTSPWKRVLITISIISVYEGIVYGFFHRWTFTLIT 582

Query: 553 SKLAF-------------LLTLITTFASVGFKITQA--WEAGEVVP-APLLYLMGLPGTL 596
           + LAF             +L +IT+     F +  A   E    +  A LL ++     L
Sbjct: 583 NILAFYPFICGVRELSVNILWIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAFYAL 642

Query: 597 NEVNARMAGLARFAFSTIAAGSLYRVLSLAGTDKVNLIRDLHAFL--------------- 641
            ++++R+    R  F  I    +  +L  A T +  +   L   L               
Sbjct: 643 YKIHSRINSYTRAIF-AIQISLVAAML--AVTHRSVISLQLRQGLPRESQVAGWIIFFVS 699

Query: 642 ------------------TLFLITQSRIQN-IPLFMVYYFLEIFLRKATNRSFIFSSRDI 682
                              L +I  +   + I L + +  L  FL  +    +I     I
Sbjct: 700 LFVMPILHYRKPNNDYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKI 759

Query: 683 YQTEALFQKL---VLVLSVSTLLLEQVSFFSMGNSNSMASIDLSNAYNGVTLYQIEFVGV 739
            + +    +    VL +SV    L QV+FF  GN  S++S  L +    + ++    +G 
Sbjct: 760 KEMKTQKDENWLQVLRVSVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGA 819

Query: 740 LTFVSNWIGPLYWS-TAGLSFLLEDHVRNAIFAKIAEKNNDVKL--------TTKLVQQA 790
           L  +   I     S   G+  L  +     I + I   ++ + L            +   
Sbjct: 820 LLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLDIG 879

Query: 791 LTLRVYVVLAFSSVAISAVM 810
           +T+  Y +   SS+ +  + 
Sbjct: 880 ITISNYCLAILSSLFMLILE 899
>sp|Q09782|YA93_SCHPO HYPOTHETICAL 85.7 KD PROTEIN C13G6.03 IN CHROMOSOME I
 pir||S62432 major facilitator protein homolog - fission yeast
           (Schizosaccharomyces pombe)
 pir||T37638 major facilitator protein homolog - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA91096.1| (Z54308) putative major facilitator superfamily protein
           [Schizosaccharomyces pombe]
          Length = 758

 Score =  606 bits (1547), Expect = e-172
 Identities = 277/868 (31%), Positives = 417/868 (47%), Gaps = 130/868 (14%)

Query: 6   WTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTES-RVSTEAPFQKAIIMVVDAFRSDFA 64
                 I  LQ+   +LF  GF P +    G   S + S  A   + + ++VDA R+DF 
Sbjct: 2   RFAFFGIFWLQIFGSILFLLGFFPHKNDSTGKAMSNQFSPPAVIDQVVFVMVDALRADFV 61

Query: 65  FSDQSNCPQLHKRI-NSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAESDN 123
           FS   N P     + NS   I F+A +  PTVT+PR+K LTTG+ P FLD +LNIAESD 
Sbjct: 62  FSKSHNMPFTQSLLYNSTHGIGFSAFARSPTVTMPRLKALTTGTIPGFLDVLLNIAESDT 121

Query: 124 SSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASFFVSDYTEVDNNVTR 183
            S++  QDSW+ Q +   +KI  +GDDTW+KLFP  F   EGT SFFVSDYTEVDNNVTR
Sbjct: 122 GSSIEAQDSWVYQLNSFNKKIEFYGDDTWLKLFPSAFSKFEGTTSFFVSDYTEVDNNVTR 181

Query: 184 HIDTQLDQKT--EWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDD-- 239
           + D  L       WD LILHYLG+DHIGH  GP SP +  K  E+D I  ++Y    +  
Sbjct: 182 NFDHALPSSLSHSWDALILHYLGVDHIGHLYGPSSPLLNIKLLEIDTIISRIYKYLQEYD 241

Query: 240 -----DTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFETAQLTETAETSPLPWTD 294
                 ++++L GDHGMNEVGNHGGSS+GET+AA+    P  E + + +          +
Sbjct: 242 EKTNTHSLIVLCGDHGMNEVGNHGGSSSGETTAALSLLFPSNELSHINKPILNMD---DN 298

Query: 295 TYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSPEDQLNVLKNNADQMVQI 354
            Y    R++Q D+VPT+  LLG+  PK N+G ++S +  LW       +   +    + +
Sbjct: 299 PYSILERVEQVDVVPTICLLLGIPIPKGNMGKVLSPVTELWKDTKTAKMAALSNLFQLSL 358

Query: 355 LQGQASRESDAKEVYELYDTLNSNPSVKDYYNFLYEAQSYLTHASSNYNTNDMLGGIGLG 414
           L+  +   S+    ++  D       + D    L   QS +   SS+Y+ + ML  I + 
Sbjct: 359 LKNPSLTTSELSTQFQDSD-------LNDIRLALENLQSQMVAQSSSYSLDRMLVAISIL 411

Query: 415 LLSTILALTVFSALTLAVQGLKRLYLIILLVYFISVFGSSTVEEEHQIWYWITSGWMAFL 474
              +IL+L +F  L    + L   +   ++   I VF SS +EEEH IWY+        L
Sbjct: 412 GACSILSLILFRNLYNYKELLA--FAPFVVQNIIIVFSSSFIEEEHVIWYFAAVSLS-LL 468

Query: 475 YISGSRNKFGDGFNWMFVQVFVRMMISWNQTGQKFTKKDDIVTWLSKDGNQPSLWILILV 534
            +   + +         + +  R    WNQTGQK++   DIV                  
Sbjct: 469 QLLNPKTRLAGSLQLFCLSIIKR----WNQTGQKYSDLRDIVD----------------- 507

Query: 535 TYGVAFNKVWRYGFSKVESKLAFLLTLITTFASVGFKITQAWEAGEVVPAPLLYL----- 589
                                 F+    +TF      +T A+      P+P+ +L     
Sbjct: 508 ---------------------DFIAP--STFMKTILCVTSAFMPAIRSPSPINFLSSMFI 544

Query: 590 --MGLPGTLNEVNARMAGLARFAFSTIAAGSLYRVLSLAGTDKVNLIRDLHAFLTLFLIT 647
               L   +++    +  +A F + T     ++ +L ++   K    + L   L+LF++ 
Sbjct: 545 AFYKLMPIISKHLNELPIIASFDY-TFFVRIIWSLLLISFLSKPTF-KQLRCQLSLFILL 602

Query: 648 QSRIQNIPLFMVYYFLEIFLRKATNRSFIFSSRDIYQTEALFQKLVLVLSVSTLLLEQVS 707
            +R++N+ L+++Y                    DI+Q   + ++  L  SV   + EQV+
Sbjct: 603 LTRLENMGLYLLY--------------------DIWQ-RTMPEEGTLA-SVMYYVAEQVA 640

Query: 708 FFSMGNSNSMASIDLSNAYNGVTLYQIEFVGVLTFVSNWIGPLYWSTAGLSFLLEDHVRN 767
           FFS+GNSNS+A++DLS AY G+  Y I  VG+L F S + G L+W               
Sbjct: 641 FFSLGNSNSLATVDLSQAYTGLDSYNIFAVGILLFTSVFAGALWWCLH------------ 688

Query: 768 AIFAKIAEKNNDVKLTTKLVQQALTLRVYVVLAFSSVAISAVMITCFFLREHLFIWTVFS 827
                  ++  D  + T                 SS++++ + I+CF +R HLF+W+VFS
Sbjct: 689 -----QPKRMMDRSVKTFW-------------IMSSISLTFLCISCFIMRHHLFVWSVFS 730

Query: 828 PKLLYQFVWTVLQFALVDVILSSIFVVL 855
           PKLLY   W  + F L   ++S+I V L
Sbjct: 731 PKLLYNASWASMYF-LAKCLISTIMVRL 757
>pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragment)
 emb|CAB70839.1| (AL137607) hypothetical protein [Homo sapiens]
          Length = 825

 Score =  602 bits (1536), Expect = e-170
 Identities = 126/816 (15%), Positives = 271/816 (32%), Gaps = 137/816 (16%)

Query: 115 VLNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFP-GMFDDCEGTAS----- 168
           V  +A+    + +   DS   ++         +G    + +F  G   D   T S     
Sbjct: 3   VSAVAKGWKENPV-EFDSLFNESKYTW----SWGSPDILPMFAKGASGDHVYTYSYDAKR 57

Query: 169 --FFVSDYTEVDNNVTRHIDTQ---------LDQK--TEWDVLILHYLGLDHIGHKTGPE 215
             F   D T++D  V  ++            L  K   E  V  LH LG+D  GH   P 
Sbjct: 58  EDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPS 117

Query: 216 SPFMPAKQKEMDDIFDKLYNSC------DDDTVLILLGDHGMNEVGNHGGSSAGETSAAM 269
           S       K++DD   ++ +        D  T  I   DHGM + G+HG     ET   +
Sbjct: 118 SRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPL 177

Query: 270 VFASP--KFETAQLTETAETSPL-PWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGV 326
           V      K+      +  + + L  W         ++Q D+ P +T+L+G+  P N++G+
Sbjct: 178 VTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGI 237

Query: 327 LVSQMLGLWSPEDQLNVLKNNADQMVQILQGQASRESDAK--EVYELYDTLNSNPSVKDY 384
           L    L       +   +  NA Q+++  + + +++ +     ++  +  L+ +      
Sbjct: 238 LPVDYLNNT-DLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQ---- 292

Query: 385 YNFLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTILALTVFSALTLAVQGLKRLYLIILL 444
           +N L +A+SY+ H       ++++      +   +  L+ +        G+  +   +  
Sbjct: 293 FNILRKARSYIKHRK----FDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGW 348

Query: 445 V----YFISVFGSSTV----EEEHQIWYWITSGWMAFLYISGSRNKFGDGFNWMFVQVFV 496
           +      I    S+ +    +E  +  + +   ++A   +            W +    +
Sbjct: 349 ISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLI-QACPWTYYVYGL 407

Query: 497 RMMISWNQTGQKFTKKDDIVTWLSKDGNQPSLWILILVTYGV---AFNKVWRYGFSKVES 553
             +  W    ++F    D+V  +        +  L+  T G+     +  +RY  +   +
Sbjct: 408 LPLPIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLT 467

Query: 554 KLAFLL--TLITTFASVGFKITQAWEAGEVVPAPLLYLMGLPGTLNEVNAR--------- 602
             A     T + T A +   ++  + +  +   PL+ ++G    ++ V            
Sbjct: 468 AFAAWPFLTRLWTRAKMT-SLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAGLLVLLLSL 526

Query: 603 ----------------------MAGLARFAFSTIAAGSLYRVLSLAGT-------DKVNL 633
                                 +  L+      +   +   +L   G            L
Sbjct: 527 CVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQIISWATL 586

Query: 634 IRDLHAFLTLFLITQSRIQNIPLFMV---------YYFLEIFLRKATNRSFIFSSRDIYQ 684
              L   L    +   R+ +I L ++         Y  L   +       +I   ++  Q
Sbjct: 587 ASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIEQETLQ 646

Query: 685 TE-------------------ALFQKLVL---VLSVSTLLLEQVSFFSMGNSNSMASIDL 722
                                  F++L L     +   +     +FF  GN  S+ S DL
Sbjct: 647 QSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIASINSFDL 706

Query: 723 SNAYNGVTLYQIEFVGVLTFVSNWIGPLY-WSTAGLSFLLEDHVRNAIFAKIAEKNNDVK 781
           ++ Y  +T++    +G L      I  +          L       ++F  +   ++ + 
Sbjct: 707 ASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLVISDIMA 766

Query: 782 LT--------TKLVQQALTLRVYVVLAFSSVAISAV 809
           L            +    ++  YV++   ++ +  +
Sbjct: 767 LHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFL 802
>pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast
           (Schizosaccharomyces pombe)
 dbj|BAA21454.1| (AB004539) ORF YLL031c [Schizosaccharomyces pombe]
 emb|CAA16901.1| (AL021766) hypothetical protein [Schizosaccharomyces pombe]
          Length = 918

 Score =  592 bits (1511), Expect = e-167
 Identities = 196/929 (21%), Positives = 344/929 (36%), Gaps = 138/929 (14%)

Query: 12  IVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAP--------------FQKAIIMVVD 57
           I++     +  F  GFL  R +L   +                       F++A+I+++D
Sbjct: 31  ILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKIFERAVIVIID 90

Query: 58  AFRSDFAFSDQSN--------CPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTP 109
           A R DF      +         P     ++   +      +  PT T  R+KGLTTGS P
Sbjct: 91  ALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLP 150

Query: 110 NFLDAVLNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDD--CEGTA 167
            F+D   N A ++      ++D+ L Q     ++I + GDDTW  LF    ++   +   
Sbjct: 151 TFIDLGSNFAGTN-----IDEDNLLLQWKSLDKQIVLLGDDTWDVLFHDYLNETLSQPAF 205

Query: 168 SFFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMD 227
           SF V D   VDN V +++   + +   +DVLI HYLG+DH+GH+ GP+ P M  K  +MD
Sbjct: 206 SFNVPDLHGVDNKVNQYVFDYI-KDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMD 264

Query: 228 DIFDKLYNSCDDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFETAQLTETAET 287
               ++ +  DD T+LI++GDHGM+  GNHGG S  E ++ +   S K     L +    
Sbjct: 265 RCVKEMMDLLDDSTLLIVMGDHGMDNKGNHGGDSFDEINSVLWMYSKKPTFGYLKQPG-- 322

Query: 288 SPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSPEDQLNVLKNN 347
                          +Q DLVPTL+ LLG   P  NLG L+ +    +  E      K N
Sbjct: 323 ----------KVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEPFYYYGDEYLSKAQKIN 372

Query: 348 ADQMVQILQGQASRESDAKEVYELYDTLNSNPSVKDY---YNFLYEAQSYLTHASSNYNT 404
             Q+ +     +  + DA +        N+N  +  Y   +++  +A SY     + ++ 
Sbjct: 373 IGQLNRFF---SEYDLDASDFLSSSVHKNNNSYLDQYFLDFDYARDAFSYFKAIWAEFSL 429

Query: 405 NDM--------LGGIGLGLLSTILALTVFSALTLAVQGLKRLYLIILLVYFISVFGSSTV 456
             M        +GG  L LL    ++    +  +A   +K L + ++L+   +   S   
Sbjct: 430 FPMIIGFLLLIIGGFNLALLMQDKSVIFRMSANMAPSVMKCLPVCLILILANNELHSPFP 489

Query: 457 EEEHQIWYWITSGWMAFLYISGSRN--KFGDGFNWMFVQVFVRMMISWNQTGQKFTKKDD 514
            E    +Y +   +   L     +    F       +  +F+  +   +     FT  +D
Sbjct: 490 AE----FYVLLPSFYILLNSFNQKLMEYFKGFVKLDYFSIFITFLHVCSFGSNSFTVWED 545

Query: 515 IVTWLSKDGNQPSLWILILVTYGVAFNKVWRYGFSKVESKLAFL-LTLITTFASVGFKIT 573
            +                LV +   F+++         S LAF+ L +I+++ +   +  
Sbjct: 546 RLCHFLIITIG-------LVMFCKCFSEMSPLFACSTYSALAFILLQVISSYVTNCREEQ 598

Query: 574 QAWEAGEVVPAP-------------LLYLMGLPGTLNEVNARMAGLARFAFS---TIAAG 617
            A+     +  P              L  + LP  L     R+ GL+   +         
Sbjct: 599 GAFCVSTYISTPDNSLRTLIVLALMALSSIILPLILQLHLRRVLGLSLKLYHLSILYFFE 658

Query: 618 SLYRVLSLA---GTDKVNLIRDLHAFLTLF---------------LITQSRIQ------- 652
            +  +  +A     +   L +  H  L                      SR +       
Sbjct: 659 LISSIFWIAHHVFANDALLEKQYHHVLYSLANTYVICILGVLIWQFFLLSRSKFAKINVI 718

Query: 653 --NIPLFMVYYFLEIFLRKA-----TNRSFIFSSRDIYQTEALFQKLVLVLSVSTLLLEQ 705
             +  +F + Y    FL++          F+     I   +          SV+  LL  
Sbjct: 719 ERSYFVFALLYSFLSFLQRPLGHLSLFSCFLQILLLIQLKQWQPSVGHNFFSVTLGLLGL 778

Query: 706 VSFFSMGNSNSMASIDLSNAY-NGVTLYQIEFVGVLTFVSNWIGPLYWSTAGLSFLLEDH 764
             FF+ GN  +++S+D + A+ +  +        +  F+     P+    +   F  E  
Sbjct: 779 SHFFTTGNQAAISSLDWNFAFIHSKSAENQAISAIFMFLHTVGAPILTCISIPLFSFEPL 838

Query: 765 VRNAIFAKIAEKNNDVKLTTKLVQQALTLRVYVVLAFSSVAISAVMITCFFLREHLFIWT 824
            +   F     +               +    +     S +         F R HL +W 
Sbjct: 839 SKKNRFLINLFR--------------FSFSFILYNLLISTSTVFF---AGFFRRHLMVWK 881

Query: 825 VFSPKLLYQFVWTVLQ--FALVDVILSSI 851
           VF+P+ +   +  V    F L+    SS+
Sbjct: 882 VFAPRFMLSGILLVTHQLFVLIQCFGSSV 910
>pir||T40715 hypothetical protein SPBC839.08c - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA17011.1| (AL021816) hypothetical protein [Schizosaccharomyces pombe]
 emb|CAB46701.1| (AL096796) hypothetical protein [Schizosaccharomyces pombe]
          Length = 935

 Score =  579 bits (1477), Expect = e-164
 Identities = 142/946 (15%), Positives = 284/946 (30%), Gaps = 164/946 (17%)

Query: 6   WTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFRSDFAF 65
             +   +V L+    + F         L+ G      + EAP ++  ++V D  R D   
Sbjct: 8   LGILFHVVFLKSIFDIYF------VTPLIHGMK-QYSAGEAPAKRLFLIVGDGLRPDKLL 60

Query: 66  SDQS----------NCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAV 115
              S            P L   I + G     +H+  PT + P    L  G   +    V
Sbjct: 61  QPHSEKVIGEEQTYAAPFLRSIIQNNGTFG-VSHTRVPTESRPGHVALIAGFYED----V 115

Query: 116 LNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASFFVSDYT 175
             + +    + + N DS   Q+       + FG +  + +F     D     +F  S   
Sbjct: 116 SAVTKGWKKNPV-NFDSVFNQSRH----TYSFGSEDILPMFSEGASDPSRVDTFMYSSEL 170

Query: 176 E--------VDNNVTRHIDTQLDQKTE----WD-------VLILHYLGLDHIGHKTGPES 216
           E        +D  V   +D  L Q  E    WD       V  LH LG+D IGH   P+S
Sbjct: 171 EDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDS 230

Query: 217 PFMPAKQKEMDDIFDKLYNSC------DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMV 270
                  + +D    +L +        D  +  +   DHGM++ G+HG  +   T   ++
Sbjct: 231 VEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPII 290

Query: 271 FASPK--FETAQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLV 328
                    T +     +   LPW  T      + Q D+   ++ L+GLN P N++G + 
Sbjct: 291 AWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIP 350

Query: 329 SQMLGLWSPEDQLNVLKNNADQMVQILQGQASRESDAKEVYELYDTLNS--NPSVKDYYN 386
              L   S   +  V   NA ++ +    +++ +      +  Y  L +        Y +
Sbjct: 351 LDYLD-CSSRRKAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASFYNS 409

Query: 387 FLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTIL-ALTVFSALTLAVQGLKRLYLIILLV 445
            + + +S     +  +               T+L  L         +      +  +  +
Sbjct: 410 VIADIESGEYEIAIEHCF---------HFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWI 460

Query: 446 YFISVFGSST-VEEEHQIWYWITSGWMAFLYISGSRNKFGDGF-----NWMFVQVFVRMM 499
            ++  F  S  +E   +I        +  +  +         F        +    +   
Sbjct: 461 GYVICFVFSLNIEPSSKIV--KPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPT 518

Query: 500 ISWNQTGQKFTKKDDIVTWLSKDGNQPSLWILILVTYG----------VAFNKVWRYGFS 549
           I        F               Q   + L+ + +           + ++   R GFS
Sbjct: 519 IFLQLIHSIFPNTKLGFKNFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFS 578

Query: 550 KVESKLAFLLTLI--------------TTFASVGFKITQAWEAGEVVPAPLLY------- 588
            +   LA    L+               +  +                + L         
Sbjct: 579 VILMGLAAWPWLLHADYAFSHKTISVSWSVLTSLLCFF-TILPVNKKESLLFIFAGGFAM 637

Query: 589 -LMGLPGTLN----------------EVNARMAGLARFAFST---------IAAGSLYRV 622
            + G+   L                  V   +  +A    +          IA   + R+
Sbjct: 638 SVAGVFYILYRRNQAFQYSSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRL 697

Query: 623 LSLAGTDKVNLIRDLH-------AFLTLFLITQSRIQNI-PLFMVYYFLEIFLRKATNRS 674
           ++        +I   H           L ++  +    +  L + +  L   +   T   
Sbjct: 698 VAFGLFITSYIIPSHHIRSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGL 757

Query: 675 FIFSSRDIYQ---------TEALFQKLVL-----VLSVSTLLLEQVSFFSMGNSNSMASI 720
           ++    ++ +         +     K  L      +S+   +   V+FF  GN  S+++ 
Sbjct: 758 WMELETELQKYTEQLHPEYSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTF 817

Query: 721 DLSNAYNGVTLYQIEFVGVLTFVSNWIGPLYWS-TAGLSFLLEDHVRNAIFAKIAEKNND 779
            L +    + ++     G L   +  +  +  S   G+       ++   F       + 
Sbjct: 818 ALDSVKRFIPVFNPVTQGALLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADI 877

Query: 780 --------VKLTTKLVQQALTLRVYVVLAFSSVAISAVMITCFFLR 817
                   VK         +++  + +  F  + I+A+      L 
Sbjct: 878 VTINFFYLVKDEGSWKDIGVSISHFCISNFLILFITALEHASAILC 923
>gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melanogaster]
          Length = 874

 Score =  565 bits (1442), Expect = e-159
 Identities = 139/907 (15%), Positives = 261/907 (28%), Gaps = 165/907 (18%)

Query: 2   LWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESR----VSTEAPFQKAIIMVVD 57
           +W  + L V +++L    V+ F         ++ G T  +       E P  + +++V D
Sbjct: 1   MWIAYALVVHVLLLGSIFVIYF------RSPVITGLTPQKHLLYYGLEPPANRLVLIVTD 54

Query: 58  AFRSDFAFSDQSN-CPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVL 116
            FR+D  F +     P L K     G +   + +  PT T P    L  G   +      
Sbjct: 55  GFRADSFFEENCRYVPNLRKIFLREGVVG-VSRTRVPTETRPGHITLIAGLYEDP----S 109

Query: 117 NIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASFFVSDYT- 175
            +     S+   + D+   ++S+     + +G +  + +F  + +  E    F+  D   
Sbjct: 110 AVLRGWKSNP-IDFDTVFNRSSQ----TYAWGANDVLNVFSHVSNGGEINLRFYNHDLDF 164

Query: 176 -------EVDNNVTRHIDTQLDQKTEW------DVLILHYLGLDHIGHKTGPESPFMPAK 222
                  E D  V + +   L QK E        V  LH LGLD  GH   P +P     
Sbjct: 165 SPGYDAYEEDEWVFKRVKLLLQQKREALQRAQNVVFFLHLLGLDTAGHVHKPGAPKFRRT 224

Query: 223 QKEMDDIFDKLYNSC-----DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFE 277
            ++ +     +Y        D  T  +L  DHGM + G                      
Sbjct: 225 LEKTEKGVYAIYQEFERVFPDKRTAYLLTADHGMTDSGA--------------------S 264

Query: 278 TAQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSP 337
            A       T              ++Q  L P ++ALLGL  P NN G L    L + S 
Sbjct: 265 RAVPKPGGRTFMPNNEGPAMPLHELEQAQLTPLMSALLGLAPPMNNFGKLPLGYLNV-SK 323

Query: 338 EDQLNVLKNNADQMVQILQGQASRESDAKEVYELYDTLNSNPSVKDYYNFLYEAQSYLTH 397
           E +      NA Q+++       +    K  +          + +    +    +  +  
Sbjct: 324 EYEAMAAHVNALQLLEQYVALQKQHK--KGFFADILLEYDVLNAEAIKRY----KDTIVQ 377

Query: 398 ASSNYNTNDMLGGIGLGLLSTILALTVFSALTLAVQGLKRLYLIILLVYFISVFGSS--- 454
                  +  +    + +   +  +  +      V  L      +  +++I    S    
Sbjct: 378 LQKKREYSLCIDKSQVIMSQALEGIDYYHGYYRRVLLLSTTSTFLGWMFYIYRLLSRNRA 437

Query: 455 -----TVEEEHQIWYWITSGWMAFLYISGSRNKFGDGFNWMFVQVFVRMMISWNQTGQKF 509
                 +E  ++I        +  L I         G         +     W +  Q +
Sbjct: 438 SKVELVLERSNKIVRVSIVSSVIVLII----CLLSQGTPLDISFYLLLPYFVWLKALQPW 493

Query: 510 TKKDDIV--TWLSKDGNQPSLWILILVTYG---VAFNKVWRYGFSKVESKLA-------- 556
                    +  S    Q S+W L+L+      + F    R   +      A        
Sbjct: 494 NINFSSSPASAYSVPALQTSMWQLVLLIACAELMVFTFFERRLIALCFCVFACYNSWENF 553

Query: 557 ------FLLTLITTFASVGFKI---------------------TQAWEAG--------EV 581
                 F   L        F +                     T ++             
Sbjct: 554 QWKSRDFFSWLALVLILSCFPLLPLSVGYQNGYLLGAGVIVIFTNSFWNSKSRLCYRNHT 613

Query: 582 VPAPLLYLMGLPGTLNEVNARMAG-----LARFAFSTIAAGSLYRVLSLAGTDKVNLIRD 636
             +  L L+         +  +       LA + +   A  S+             L ++
Sbjct: 614 KYSNALILLQTILCAYLHSNGINIPIPLKLASWLYLVYAFASI------------LLSKE 661

Query: 637 LHAFLTLF-LITQSRIQNIPLFMVYYFLEIFLRKATNRSFIFSSRDIYQTEALFQKLVLV 695
               L L  +          L   Y  + + L        +  S       A    L L 
Sbjct: 662 SRLDLRLAQIGFNLGSLYATLCTSYEAVFVQLLTIE----LNISLRAQSARAERSVLRLA 717

Query: 696 LSVSTLLLEQVSFFSMGNSNSMASIDLSNAYNGVTLYQIEF-VGVLTFVSNWIGPLYWST 754
            ++        S F  GN  S++S D + A   ++ +     +G++         L  S 
Sbjct: 718 FTLLLYTF--FSLFGSGNIASISSFDPNIARCYLSHFAPFVIMGLVLLKLLVPVVLIMSV 775

Query: 755 AGLSFLLEDHVRNAIFAKIAEKNNDV--------KLTTKLVQQALTLRVYVV-----LAF 801
              +          IF  +    + +        +     +    ++  +V+     L  
Sbjct: 776 IYANSEFVRQHEEQIFICLLLICDVMGLNFLFLVRNQGSWLDIGTSISHFVIMEVTTLVM 835

Query: 802 SSVAISA 808
             +  +A
Sbjct: 836 LVIFYTA 842
>ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
 gb|AAF24617.1|AC010870_10 (AC010870) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
          Length = 921

 Score =  554 bits (1415), Expect = e-156
 Identities = 141/899 (15%), Positives = 291/899 (31%), Gaps = 139/899 (15%)

Query: 5   RWTLAVTIVVLQLAAVLLFARGF-LPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFRSDF 63
            W + + + +  +  + +F   F  P    +          E P ++ ++++ D  R+D 
Sbjct: 44  TWLVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFS--EPPAKRLVLLISDGLRADK 101

Query: 64  AF----SDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIA 119
            F      +   P L   I + G     +H+ PPT + P    +  G   +       + 
Sbjct: 102 FFEPDEEGKYRAPFLRNIIKNQGRWG-VSHARPPTESRPGHVAIIAGFYEDP----SAVT 156

Query: 120 ESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLF------------PGMFDDCEGTA 167
           +   ++ +   DS   Q+         FG    I +F            P  ++D    A
Sbjct: 157 KGWKANPV-EFDSVFNQSRH----TFAFGSPDIIPIFCSALPHSTWNSYPHEYEDFATDA 211

Query: 168 SF-FVSDYTEVDNNVTR-HIDTQLDQKTEWD--VLILHYLGLDHIGHKTGPESPFMPAKQ 223
           SF     + + +  + R H D +L +    D  V+ LH LG D  GH   P S       
Sbjct: 212 SFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNV 271

Query: 224 KEMDDIFDKLYNSC-----DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFE- 277
           K +D I +++Y+       D+ T  I   DHGM++ G+HG      T   +V      + 
Sbjct: 272 KVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQY 331

Query: 278 -------------TAQLTETAETSPLPWTDTYKYHS--RMDQTDLVPTLTALLGLNTPKN 322
                        T  + + A   P P+    +      ++Q D+ P ++ LLGL  P N
Sbjct: 332 PKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVN 391

Query: 323 NLGVLVSQMLGLWSPEDQLNVLKNNADQMVQILQGQASRESDAKEVYELYDTL-NSNPSV 381
           ++G L    + L    +++  +  N  Q++  L  ++  +S     ++ +  L + + S+
Sbjct: 392 SVGNLPLGYMKLNE-AEEVEAVVANTKQILNQLLRKSYIKSSNSLFFKPFKPLVHHSFSL 450

Query: 382 KDYYNFLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTILALTVFSALTLAVQGLKRLYLI 441
               + L  A+SY        +    L   GL    T   L + + +TL   G   + L 
Sbjct: 451 SQI-DELISAKSYEAAMKLAVDL-RNLSLEGLHYFQTYDWLMLMTVITLGYTG-WMIVLA 507

Query: 442 ILLVYFISVFGSSTVEEEHQIWYWITSGWMAFLYISGSRNKFGDGFNWMFVQVFVRMMIS 501
           + ++   S       ++EH   Y      MA L +        +    ++       +  
Sbjct: 508 LHVLQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLN----LVEHSPPLYHAYIGMTVFL 563

Query: 502 WNQTGQKFTKKDDIVTWLSKDGNQPSLWILILVTY------GVAFNKVWRYGFSKVESK- 554
           W Q   ++     +  +L +      + +L            +  +   R  ++      
Sbjct: 564 WTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFLIA 623

Query: 555 -------LAF-LLTL--ITTFASVGFKITQAWEAGEVVPAP-LLYLMGLPGTLNEVNARM 603
                  L F +     I  F  +      +         P    L+      N+ +   
Sbjct: 624 GVVASILLHFSIPWRSGIPVFVCI-SCWFLSVFTLMPAEIPDNNNLVSPFLGANDTD--- 679

Query: 604 AGLARFAFSTIAAGSLYRVLSLAGTDKVNLIRDLHAFLTLFLITQSRIQNIPLFMVYYFL 663
                             +           + D  +     +   +   +  +   Y  +
Sbjct: 680 ------------------IFGWCVICDGVFV-DKASNAESRIAFVT-SVHKLVSCRYEAV 719

Query: 664 EIFLRKATNRSFIFSSR----DIYQTEALFQKLVL------------------VLSVSTL 701
                     ++I             E+   +                      + +  +
Sbjct: 720 FYSALAVVLMAWILFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFM 779

Query: 702 LLEQVSFFSMGNSNSMASIDLSNAYNGVTLYQIEFVGVLTFVSNWIGPLYW-STAGLSFL 760
           +L  V+FF  GN  S+AS ++S+ Y  +T++    +  L     +I  +           
Sbjct: 780 VLFNVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITK 839

Query: 761 LEDHVRNAIFAKIAEKNNDV--------KLTTKLVQQALTLRVYVVLAFSSVAISAVMI 811
           L    R   +  +   ++ +        K T   ++   ++  +      S  +  V++
Sbjct: 840 LVRVPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNSISHF---GIVSAQVVFVLL 895
>ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]
 gb|AAB93646.1| (AF003137) Hypothetical protein C27A12.9 [Caenorhabditis elegans]
          Length = 905

 Score =  544 bits (1388), Expect = e-153
 Identities = 180/965 (18%), Positives = 336/965 (34%), Gaps = 220/965 (22%)

Query: 4   KRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAP---------FQKAIIM 54
               L V+I +L      +F  GFL  R  +   +    +   P         +Q+ I++
Sbjct: 4   IIRILLVSINILLALF--IFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILI 61

Query: 55  VVDAFRSDFAFS-------------DQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIK 101
           +VDA R DF                 +     + K + SG     T  + PPT TL R+K
Sbjct: 62  LVDALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLK 121

Query: 102 GLTTGSTPNFLDAVLNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFD 161
            LTTG+ P F+DA  N +       + ++DS++ QA++ G+ + + GDDTW+ LFP  F 
Sbjct: 122 ALTTGTLPTFIDAGDNFSPD----AVISEDSFVYQAAQLGKNVTLLGDDTWLSLFPNQFS 177

Query: 162 DCEGTASFFVSDYTEVDNNVTRH-------------IDTQLDQKT----EWDVLILHYLG 204
                 SF ++D   VD+ + R               +  + Q         ++I H+LG
Sbjct: 178 KTAAYDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLG 237

Query: 205 LDHIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDTVLILLGDHGMNEVGNHGGSSAGE 264
           +DH GHK GP  P M    ++MD I  +   +   D       DHGM   G+HGG S  E
Sbjct: 238 VDHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKSD-------DHGMTSTGDHGGESENE 290

Query: 265 TSAAMVFASPKFETAQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNL 324
             A ++  S K +                        + Q D+VPT++ L+GL  P +NL
Sbjct: 291 IRAGILVHSKKHQIILPERP-----------------IHQIDIVPTISLLMGLPIPFSNL 333

Query: 325 GVLVSQML--GLWSPEDQLNVLKNNADQMVQILQGQASRESDAKEVYELYDTLNSNPSVK 382
           G +++Q+    LW    Q+       D +    +  A++++   E++    T+  + +++
Sbjct: 334 GTVITQLFTRDLWEIARQMMGFVWQ-DSVGIFAETYAAQKNF-GELH--SHTIRDSNTME 389

Query: 383 DYYNFLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTILALTVFSALTLAVQGLKRLY--- 439
           +  + +   Q+ L  + + ++       I  G+ S + A+         +     +Y   
Sbjct: 390 EQLDTMSRIQTLLRVSWTQFDDA----YINAGIFSLVEAIMFLIT-NEVMSLEWIIYRTG 444

Query: 440 --------------------LIILLVYFISVFGS-------------------------- 453
                                ++L+   +S   S                          
Sbjct: 445 CGLLQAALLTDKTDSDGSARTLLLMTLAVSCLSSIISMCHKALQIRISIKSMLSAKVIGP 504

Query: 454 -------------STVEEEHQIWYWITSGWMAFLYI-------SGSRNKFGDGFNWMFV- 492
                        S V  E Q+  +     +  +++          R  F   F W FV 
Sbjct: 505 ILVIIHSISLFSNSYVVYEAQVVRYFLQSLVTLVFLEKLRSTALRPRKPFKLNFLWKFVN 564

Query: 493 -----------QVFVRMMISWNQTGQKF----TKKDDIVTWLSKDGNQPSLWILILVTYG 537
                       V +R    +++  ++     T              Q    +  L +  
Sbjct: 565 QDQNLIIFTLIMVGLRSEPIFHRCREEEVGCDTYYPSRQAGSLTRDAQVVRLLFALGSLA 624

Query: 538 VA-FNKVWRYGFSKVESKLAFLLTLITTFASVGFKITQAWEAGEVVPAPLLYLMGLPGTL 596
           VA  +    YG    +S++       +    +    +        +   ++ L  +  +L
Sbjct: 625 VANLSVFKYYGLRDTKSQIESNSKRSSETIRILSATSW-------LHIAIIVLHSVFASL 677

Query: 597 NEVNARMAGLARFAFSTIAAGSLYRVLSLAGTDKVNLIRDLHAFLTLFLITQSRIQNIPL 656
               +R    A    S      +  VL+    +          FL + +        IP 
Sbjct: 678 THDVSRANLSA---HSLSVISLICAVLAWREGNSAICA----HFLLMPVYILFGDGLIPA 730

Query: 657 FMVYYFLEIFLRKATNRSFIFSSRDIYQTEALFQKLVLVLSVSTLLLEQVSFFSMGNSNS 716
            +++  + + + +  +R FI S+                      LL  + F+ +G+S  
Sbjct: 731 IIIFIAVSVLIAEFVSREFIAST--------------------IALLIPLGFYHLGHSPV 770

Query: 717 MASIDLSNAYNGVTLYQIEFVGVLTFVSNWIGPLYWSTAGLSFLLEDHVRNAIFAKIAEK 776
           ++SI  + A+ G+                             F+L     +AI +     
Sbjct: 771 ISSIPWNAAFVGIPGGTALR-----------------VLPALFVLFHLNFSAISSIFVIS 813

Query: 777 NNDVKLTTKL-VQQALTLRVYVVLAFSSVAISAVMITCFFLREHLFIWTVFSPKLLYQFV 835
           +             A TL   +VL      ++   +     R HL +W +F+PK +++ +
Sbjct: 814 SESESSQKMSAPNTAWTLTETLVLMTIRATLTC--LVSSIHRRHLMVWKIFAPKFIFECI 871

Query: 836 WTVLQ 840
            T++ 
Sbjct: 872 LTIVF 876
 Score =  168 bits (423), Expect = 4e-40
 Identities = 57/402 (14%), Positives = 125/402 (30%), Gaps = 79/402 (19%)

Query: 399 SSNYNTNDMLGGIGLG---LLSTILALTVFSALTLAVQGLKRLYLIILLVYFISVFGSST 455
            S      M   +      +     AL +  ++  ++   K +  I+++++ IS+F +S 
Sbjct: 461 GSARTLLLMTLAVSCLSSIISMCHKALQIRISI-KSMLSAKVIGPILVIIHSISLFSNSY 519

Query: 456 VEEEHQIWYWITSGWMAFLYI-------SGSRNKFGDGFNWMFV------------QVFV 496
           V  E Q+  +     +  +++          R  F   F W FV             V +
Sbjct: 520 VVYEAQVVRYFLQSLVTLVFLEKLRSTALRPRKPFKLNFLWKFVNQDQNLIIFTLIMVGL 579

Query: 497 RMMISWNQTGQKF----TKKDDIVTWLSKDGNQPSLWILILVTYGVA-FNKVWRYGFSKV 551
           R    +++  ++     T              Q    +  L +  VA  +    YG    
Sbjct: 580 RSEPIFHRCREEEVGCDTYYPSRQAGSLTRDAQVVRLLFALGSLAVANLSVFKYYGLRDT 639

Query: 552 ESKLAFLLTLITTFASVGFKITQAWEAGEVVPAPLLYLMGLPGTLNEVNARMAGLARFAF 611
           +S++       +    +    +        +   ++ L  +  +L    +R    A    
Sbjct: 640 KSQIESNSKRSSETIRILSATSW-------LHIAIIVLHSVFASLTHDVSRANLSA---H 689

Query: 612 STIAAGSLYRVLSLAGTDKVNLIRDLHAFLTLFLITQSRIQNIPLFMVYYFLEIFLRKAT 671
           S      +  VL+    +          FL + +        IP  +++  + + + +  
Sbjct: 690 SLSVISLICAVLAWREGNSAICA----HFLLMPVYILFGDGLIPAIIIFIAVSVLIAEFV 745

Query: 672 NRSFIFSSRDIYQTEALFQKLVLVLSVSTLLLEQVSFFSMGNSNSMASIDLSNAYNGVTL 731
           +R FI S+                      LL  + F+ +G+S  ++SI  + A+ G+  
Sbjct: 746 SREFIAST--------------------IALLIPLGFYHLGHSPVISSIPWNAAFVGIPG 785

Query: 732 YQIEFVGVLTFVSNWIGPLYWSTAGLSFLLEDHVRNAIFAKI 773
                                      F+L     +AI +  
Sbjct: 786 GTALR-----------------VLPALFVLFHLNFSAISSIF 810
>gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melanogaster]
          Length = 919

 Score =  542 bits (1383), Expect = e-153
 Identities = 114/903 (12%), Positives = 236/903 (25%), Gaps = 142/903 (15%)

Query: 2   LWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFRS 61
           +W    L V +++L     + F    L    L P  T   +  E P  + ++ VVD  R+
Sbjct: 1   MWSIQALVVHLLLLGSILSIYFQSTIL--SDLEPLSTLRELGLEPPADRLVVFVVDGLRA 58

Query: 62  DFAFSDQSNC-PQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAE 120
               +D  +  P L +       +   + + PPTVT P    +  G   +          
Sbjct: 59  QSVLADHCSAVPDLRELFVEQALVG-ISRACPPTVTRPGHIAIFGGFNEDP-----AATL 112

Query: 121 SDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFD-----DCEGTASFFVSDYT 175
           + N ST    DS   ++         +      K+F  +         E  A   +SD  
Sbjct: 113 TWNPST---FDSVFNRSR----NAIGWMQAEVAKVFTHLPTGGAPLRFETFARSDISDRL 165

Query: 176 EVDNNVTRHIDTQLDQ--------KTEWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMD 227
            +D      +   +               +  ++   +D   H   P S     K     
Sbjct: 166 RLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQ 225

Query: 228 DIFDKLYNSC-----DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFETAQLT 282
               + Y        D  T  ++  D+G++    HGG          +      + +   
Sbjct: 226 RGIRQTYELFESVFNDSRTAYLMTADYGISL---HGGGGERGVETPFILWGAGVKRSAPN 282

Query: 283 ETAETSPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSPEDQLN 342
              +              +++Q  L P ++AL+GL  P NN+ ++    L   S + +L 
Sbjct: 283 -PGQNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLN-TSVQYELQ 340

Query: 343 VLKNNADQMVQILQGQASRESDAKEVYELYDTLNSNPSVKDYYNFLYEAQSYLTHASSNY 402
           VL  NA Q++     +   +     +  L      +    +  N+    + YL      Y
Sbjct: 341 VLHLNAMQLLAQ--ARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIK-YLVA-KEQY 396

Query: 403 NTNDMLGGIGLGLLSTILALTVFSALTLAVQGLKRLYLIILLVYFISVFG---SSTVEEE 459
                +      L      +  +         +      ++  Y + V     S+  + E
Sbjct: 397 EEALKVSHKIAKLAQ--ECMEYYHGYYHLPLLVATTASYLVWFYLLLVRLARESNHPKSE 454

Query: 460 HQIWYWITSGWMAFLYISGSRNKFGDGFNWMFVQVFVRMMISWNQTGQKFT--------- 510
            + +   T+  M    +             +     +           +           
Sbjct: 455 RKGYLTWTTLMMCLGGLVLLELMILQRVPHLTAFYLLLPFGILILALAERPCQDRDLMCQ 514

Query: 511 ---------KKDDIVTWLSKDGNQPSLWILILVTYGVAFNKVWRYGFSKVESKLAFLLTL 561
                        ++  L    N        L+   +      R  F      L  +  L
Sbjct: 515 FPVLHLVGIVMPGVLLILMAFHNSHIG----LLYLPIVCLNNRRAFFRPS---LKLIFWL 567

Query: 562 ITTFASV--------------GFKITQAWEAGEVVPAPLLYLMGLPGTLNEVNAR----- 602
              F                    I        VV   ++  +  P  L   ++      
Sbjct: 568 ALVFLLSGILLVKQSASLHFITDTIGVYIGNSHVVYFSMILSIIRPLILGHQHSTRVWIV 627

Query: 603 ----MAGLARFAFS--------TIAAGSLYRVLSLAGTDKVNLIRDLHAFLTLFLITQSR 650
               +   A   +         T    + +  L  A                  +I    
Sbjct: 628 NMAALLVTAYGIYQWDADQPVCTYVYAACWSYLLFAFLSIPYSGTKDLRRRLELIIFNML 687

Query: 651 IQNIPLFMVYYFLEIFLRKATNRSFIFSSRDI-------------------YQTEALFQK 691
             +I L      L + +        +    +                     +       
Sbjct: 688 TVHIMLTTSIGSLFVQIMVTEFVLGLELYEESFSYANLKDAIANQQQNNQGLEESRNESP 747

Query: 692 LVLVLSV--------STLLLEQVSFFSMGNSNSMASIDLSNAYNGVTLYQIEFVGVLTFV 743
              +  V          LL   +SFF  G+     +     +      + +  +     +
Sbjct: 748 NNPLEHVRQSYRYAALILLYLYISFFGTGHWFFNFTFKPMTSRLFFPQFHLHMLVAFILL 807

Query: 744 SNWIGPLYWSTAGLSFLLEDHVRNAIFAKIAEKNNDVKLTTKLVQQALTLRVYVVLAFSS 803
             +I  +   ++   + L    R  + +              L+  A++L  +     + 
Sbjct: 808 KIFIPSIIVMSSI--YALVSFGRKNVRSIFI--------CLFLMNDAMSL-YFCYFVINR 856

Query: 804 VAI 806
            ++
Sbjct: 857 GSL 859
>ref|NP_495820.1| (NM_063419) Yeast YJ10 like [Caenorhabditis elegans]
 pir||T21487 hypothetical protein F28C6.4 - Caenorhabditis elegans
 emb|CAA92675.1| (Z68315) Similarity to Yeast hypothetical protein YJ10
           (SW:YJ10_YEAST)~cDNA EST yk160e12.5 comes from this
           gene~cDNA EST yk160e12.3 comes from this gene~cDNA EST
           yk317h4.3 comes from this gene~cDNA EST yk317h4.5 comes
           from this gene [Caenorhabditis ele>
          Length = 795

 Score =  487 bits (1242), Expect = e-136
 Identities = 186/699 (26%), Positives = 304/699 (42%), Gaps = 69/699 (9%)

Query: 3   WKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFRSD 62
           W    L V    L + + +       P          ++ S+ +P  + + MV+DAFR  
Sbjct: 59  WISRVLVVCACALLVYSFVALDITPTPPTEEFGFKDGNQESSSSP--RLVFMVIDAFRLS 116

Query: 63  FAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAESD 122
           F  S +S        I    A  F A++  PTVTLPRI    TG+ P+F   + N+A ++
Sbjct: 117 FLTSSKSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAE 176

Query: 123 NSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASFFVSDYTEVDNNVT 182
             +      +W+++  + G+K+H FGDDTWI+L P  F+  EG  SFFVSDYT+VDNNVT
Sbjct: 177 MKTA-----NWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVT 231

Query: 183 RHIDTQLDQKTE-WDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDT 241
           RH+DT+L      WD LILHYLGLDHIGH  G  S  +P K KEMDD+  +++      T
Sbjct: 232 RHLDTELSNTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSST 291

Query: 242 V------LILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFETAQLTETAETSPLPWTDT 295
                  LI+ GDHGM   G+HGG+S  ET   +V    KF   +  +          D+
Sbjct: 292 SVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIW--KFGREEGNKNYGN----QDDS 345

Query: 296 YKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSPEDQLNVLKNNADQMVQIL 355
            K   R++Q D+  T+  +  +  P  + G+    ++  +S +++    +   +Q  +I+
Sbjct: 346 LKQPPRIEQIDVSSTIFDVFNMPIPIESYGI---SLINYFSDDEE-EYFEKQHNQFRRIV 401

Query: 356 QGQASRESDAKEVYELYDTLNSNPSVKDYYNFLYEAQSYLTHASSNYNTNDMLGGIGLGL 415
           Q +    SD  +    Y       ++K ++      QS L  ++S               
Sbjct: 402 QAKHLAISDICDENCDYSDKFIKSALKKWFL---TVQSELIGSASEVPNK---------- 448

Query: 416 LSTILALTVFSALTLAVQGLKRLYL----IILLVYFISVFGSSTVEEEHQIWYWITSGWM 471
              +    +  ALTL++ GL  L+L      + +  I+ F SS +EEEH+IWY++ S  +
Sbjct: 449 SLGVCVFLLLVALTLSM-GLWNLHLSKSDFFIFLINITYFASSLIEEEHEIWYYLGSTVV 507

Query: 472 AFLYISGSRNKFGDGFNWMFVQVFV-RMMISWNQTGQKFTKKDDIVTWLSKDGN----QP 526
           A   +   +         +F   F+ R+  S+ Q+ ++    D  +   S   +    QP
Sbjct: 508 AIRALRNFKIWNKTEVKSIFFLAFLHRIACSYTQSTRRRWIMDSSLLPPSIFSDTLDFQP 567

Query: 527 SLWILILVTYGVA----FNKVWRYGFSKVESKLAFLLTLITTFASVGFKITQAWEAGEVV 582
           +    IL  Y +      +  W YG+   +SK   +L +++ F    F++TQ  E     
Sbjct: 568 NNLNTILNEYPIIVILTCSLFWMYGYK--QSKFHIILPMVSHFLR-LFELTQFNEVLMH- 623

Query: 583 PAPLLYLMGLPGTLNEVNARMAGLARFAFSTIAAGSLYRVLSLAG-------TDKVNLIR 635
                  + +        + +AG        +A   + ++L L           K+NL  
Sbjct: 624 ----FIRLSILPISYSTGSVLAGC---LPLLLAIVPVSQILLLLVIYNMGKLFSKLNLGS 676

Query: 636 DLHAFLTLFLITQSRIQNIPLFMVYYFLEIFLRKATNRS 674
                L +     +   N    +      + L       
Sbjct: 677 VEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPIL 715
 Score = 96.8 bits (239), Expect = 1e-18
 Identities = 52/216 (24%), Positives = 86/216 (39%), Gaps = 38/216 (17%)

Query: 633 LIRDLHAFLTLFLITQSRIQNIPLFMVYYFLEIFLRKATNRSFIFSSRDIYQTEALFQKL 692
               L  F+ L ++  S      L          L      S I     IY    LF KL
Sbjct: 617 FNEVLMHFIRLSILPISYSTGSVLAGCL----PLLLAIVPVSQILLLLVIYNMGKLFSKL 672

Query: 693 VLVLSVSTLLLEQVSFFSMGNSNSMASIDLSNAYNGVTLYQIEFVGVLTFVSNWIGPLYW 752
            L  SV  + L   SFF  GNSNS++++ L++AY G++ YQ   VG+   +  + GP+ +
Sbjct: 673 NL-GSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPILVGLQLMLYTFSGPILF 731

Query: 753 STAGLSFLLEDHVRNAIFAKIAEKNNDVKLTTKLVQQALTLRVYVVLAFSSVAISAVMIT 812
                                     +    T L+    +           ++     + 
Sbjct: 732 LCGC----------------------NASSCTSLLNHLFSY---------RISSMCTSLI 760

Query: 813 C-FFLREHLFIWTVFSPKLLYQFVWTVLQFALVDVI 847
           C +  + HLFIW+V+SPK++Y  +  V+ F L+ ++
Sbjct: 761 CLYIFQNHLFIWSVYSPKVVYD-MAHVIFFGLIGLL 795
>gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caenorhabditis elegans]
          Length = 929

 Score =  485 bits (1238), Expect = e-136
 Identities = 109/662 (16%), Positives = 207/662 (30%), Gaps = 94/662 (14%)

Query: 1   MLWKRWT--LAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESR-VSTEAPFQKAIIMVVD 57
           M WK     + V +V++     + +         L+ G       S EAP ++  I+  D
Sbjct: 1   MSWKFLIASITVHLVLIYSIFDVYYTS------PLVHGIPPQFINSQEAPAKRIFIISAD 54

Query: 58  AFRSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLN 117
             R D         P LH  +N    I   + S  PT + P    +  G T +    +  
Sbjct: 55  GLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITED----ISA 110

Query: 118 IAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTAS-----FFVS 172
           +A+    + +   DS   ++S       M+G    + LF  + +    + S     F   
Sbjct: 111 VAKGWKKNPV-QFDSVFNRSSYSW----MWGSPDIVNLFDDLPNAESFSYSADEEDFASK 165

Query: 173 DYTEVDNNVTRHIDTQL-----------DQKTEWDVLILHYLGLDHIGHKTGPESPFMPA 221
           D + +D  V  H +  L             + +  +  LH LG+D  GH   P S     
Sbjct: 166 DASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYID 225

Query: 222 KQKEMDDIFDKLYNSC-----DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKF 276
             K +D   +K+ +       D  T  +   DHGM + G+HG  S  E     V      
Sbjct: 226 NIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGV 285

Query: 277 ETAQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWS 336
           +                        ++Q DL P ++AL+G   P N++G+L  QM+    
Sbjct: 286 KQGGPK-----------------LDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKG 328

Query: 337 PEDQLNVLKNNADQMVQILQGQASRESDAKEVYELYDTLNSNPSVKDYYNFLYEAQSYLT 396
              +   ++ N  Q+ + +    + +S           L      K     +   ++ L 
Sbjct: 329 SSYEFKAIEANFKQLKEQIIFLKNAKS---------RRLWFRQFEKFGDKAMESLRTTLA 379

Query: 397 HASSNYNTNDMLGGIGLGLLSTILALTVFSALTLAVQGLKRLYLIILLV-YFISVFGSST 455
               +   +               A+  +      + G       +  +   +S   +ST
Sbjct: 380 QLGRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIALVVSFLHNST 439

Query: 456 VEEE-------HQIWYWITSGWMAFLYISGSRNKFGDGFNWMFVQVFVRMMISWNQTGQK 508
            +E        H     +    +   Y S S  +       +++   +       Q  ++
Sbjct: 440 SKENLSLLVPHHLFIIPLACSLLFTAYCSLSMTQTIYIILPIYLISILENHSKLTQRIRE 499

Query: 509 F-------TKKDDIVTWLSKDGNQPSLWILILVTYGV-AFNKVWRYGFSKVESKLAFLLT 560
                       + V  +         ++   +T  +     + R   + V   L  L  
Sbjct: 500 HVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAVFVLLMALPQ 559

Query: 561 LITTFASVGFKITQAWEAGEVVPAPLLYLMGL-----PGTLNEV--------NARMAGLA 607
             +      +  T       +   P L  +G+        L+ +         +R + L 
Sbjct: 560 FYSHPIVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFLCHRLSRRSCLT 619

Query: 608 RF 609
           R 
Sbjct: 620 RI 621
 Score =  134 bits (335), Expect = 6e-30
 Identities = 25/210 (11%), Positives = 59/210 (27%), Gaps = 26/210 (12%)

Query: 617 GSLYRVLSLAGTDKVNLIRDL-----HAFLTLFLITQSRIQNIPLFMVYYFLEIFLRKAT 671
            S+ R +S        +   L          +       +    L + Y  L + +    
Sbjct: 673 PSIARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFLVL 732

Query: 672 NRSFIFSS---------RDIYQTEALFQKL---VLVLSVSTLLLEQVSFFSMGNSNSMAS 719
              F+              +              L  +V  +       F  GN  S+ S
Sbjct: 733 LTLFVRFEFGHLSDVELLQLKVDSTKISTGEYVELRRTVVCVSFVLCPLFGTGNFASINS 792

Query: 720 IDLSNAYNGVTLYQIEFVGVLTFVSNWIGPLYWSTAGLSFLLEDHV-------RNAIFAK 772
            + S     ++++    + +L  +   I  L  ++A  S +  D          + IF  
Sbjct: 793 FNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQESIQRLCCFSLIFTD 852

Query: 773 IAEKN--NDVKLTTKLVQQALTLRVYVVLA 800
                  + ++     +   +++  ++V  
Sbjct: 853 FMSMCFFHQLRDEGSWLDIGMSISQFIVSM 882
>gb|AAF54657.1| (AE003692) CG6790 gene product [Drosophila melanogaster]
 gb|AAL28155.1| (AY060607) GH02677p [Drosophila melanogaster]
          Length = 858

 Score =  453 bits (1154), Expect = e-126
 Identities = 89/664 (13%), Positives = 178/664 (26%), Gaps = 80/664 (12%)

Query: 222 KQKEMDDIFDKLYNSC-----DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKF 276
           K           Y        D  T  +    HG+   G+HGG S  E  A  +      
Sbjct: 183 KLHNTQRNIRDAYELIEATFNDSKTAYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGV 242

Query: 277 ETAQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWS 336
           +   +TE   +  +          ++DQ  L P ++AL+GL  P NNL +L    + + S
Sbjct: 243 K--HVTENITSDFVLNNGVGMQLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKV-S 299

Query: 337 PEDQLNVLKNNADQMVQILQGQASRESDAKEVYELYDTLNSNPSVKDYYNFLYEAQSYLT 396
            E     +  NA Q++     +A      + V+  +   + +  ++    +  +    L 
Sbjct: 300 REYARKSVHLNALQLLTQ--AKAIIRLHERGVFHKWLPKDKDLDLQQIAYYQNQMDHLLD 357

Query: 397 HASSNYNTNDMLGGIGLGLLSTILALTVFSALTLAVQGLKRLYLIILLVYFISVFGSSTV 456
               +         I +     + +L  +         +  +  ++   ++  V  S  V
Sbjct: 358 MGWRSKALETSTLAIKV----ALKSLKFYHNYYHIPLVVTTVLALLGWQFYQLVKLSQNV 413

Query: 457 EEEHQ---IWYWITSGWMAFLYISGSRNKFGDGFNWMFVQVFVRMMISWNQTGQ------ 507
              H     +    + ++A L +      F     +M V   V     W  T        
Sbjct: 414 MAPHYMRRGYLTWCTIFLASLGLLLGEMVFLQWAPFMTVICLVVPFGVWCMTLAALPQNG 473

Query: 508 ----------KFTKKDDIVTWLSKDGNQPSLWILILVTYGVAFNKVWRYGFSKVESKLAF 557
                     ++      V   S   N P    L L           R         LA+
Sbjct: 474 GWIFEPLKHLRWIVGPAAVMIASIYCNCP----LSLAYILCVGFYNRRGWLHPSPKFLAW 529

Query: 558 LLTLITTFASVGFKITQAWEA-----GEVVPAPLLYLMGLPGTLNEVN--------ARMA 604
           L  ++     +  +              +    +L ++  P  LNE +          + 
Sbjct: 530 LALVLLLGGFLWSQKGMQILMTTNYRVVLQAISMLVVIVRPCVLNENHKWKVWVINGGIL 589

Query: 605 GLARF---------AFSTIAAGSLYRVLSLAGTDKVNLIRDLHAFLTLFLITQSRIQNIP 655
            +A                   + +  L  A        R         +       ++ 
Sbjct: 590 FVAAIGIFLKEMGKPVPLYLFAANWAYLIYAFASVPCSSRTTPQSRLELIRFNLLTLHVL 649

Query: 656 LFMVYYFLEIFLRKATNRSFIFSSRDIYQT--------EALFQKLVLVLSVSTLLLEQVS 707
           L   Y  L         +  +       +          +   ++    +VS LL    S
Sbjct: 650 LSDSYVSLFAQGLIIEYQMGLEVHEKFKEADEDVKILTSSKHLQMCYRFAVSILLYFYAS 709

Query: 708 FFSMGNSNSMASIDLSNAYNGVTLYQIEFVGVLTFVSNWIGPLYWSTAGLSFLLEDHVRN 767
            F  G+     +   ++A   +       V +L  +   I  +    + +   L    R 
Sbjct: 710 LFGTGHWVGGFTYLANSARLFLPDSSSGLVPLLVLIHLLIPSIVIMASVV--ALSSFGRQ 767

Query: 768 AIFAKIAEKNNDVKLTTK-----------LVQQALTLRVYVVLAFSSVAISAVMITCFFL 816
            I    +                            ++   ++   + + I A        
Sbjct: 768 QIRTIFSSLMLICNAVVLFFVVFVPHNAYWPMAHPSVVHALLAQLTVILILACESIVTIF 827

Query: 817 REHL 820
              L
Sbjct: 828 FRRL 831
 Score = 94.1 bits (232), Expect = 9e-18
 Identities = 25/136 (18%), Positives = 50/136 (36%), Gaps = 15/136 (11%)

Query: 2   LWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFRS 61
           LWK   + V +++L     + +  G L    L P  T   +       + ++ +++  R+
Sbjct: 3   LWKSKVVLVHLLLLICIMRIFYQSGPL--SQLEPQKTLLDMGVPPAADRLVVFLLEGLRA 60

Query: 62  DFAFSDQSN-CPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAE 120
           D  FSD  +    +   I   G +   + ++ PT+T      L  G  P           
Sbjct: 61  DTLFSDNCSGAVYIRDIILRQGLVG-ISKTSVPTLTRSAEVALFAGFNP----------- 108

Query: 121 SDNSSTLANQDSWLAQ 136
             +    +N D+   +
Sbjct: 109 MPSILPTSNFDTIFNR 124
>dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [Mus musculus]
          Length = 391

 Score =  423 bits (1077), Expect = e-117
 Identities = 83/407 (20%), Positives = 146/407 (35%), Gaps = 51/407 (12%)

Query: 1   MLWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFR 60
           +L+    L +  V       + F         L+ G T        P ++ ++ V D  R
Sbjct: 2   LLFFALGLLIHFVFFASIFDIYFTS------PLVHGMTPQFTPLPPPAKRLVLFVADGLR 55

Query: 61  SDFAFS----DQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVL 116
           +D  +       S  P +   I   G+    +H+  PT + P    L  G   +    V 
Sbjct: 56  ADTLYELDEDGNSRAPFIRNVIMHEGSWG-VSHTRVPTESRPGHVALIAGFYED----VS 110

Query: 117 NIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFP-GMFDDCEGTAS------- 168
            +A+    + +   DS   ++         +G    + +F  G   D   T S       
Sbjct: 111 AVAKGWKENPV-EFDSLFNESKYTW----SWGSPDILPMFAKGASGDHVYTYSYDAQRED 165

Query: 169 FFVSDYTEVDNNVTRHIDTQLDQK-----------TEWDVLILHYLGLDHIGHKTGPESP 217
           F   D T++D  V   +    D              E  V  LH LG+D  GH   P S 
Sbjct: 166 FGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSR 225

Query: 218 FMPAKQKEMDDIFDKLYNSC------DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVF 271
                 K++DD   ++ +        D  T  I   DHGM + G+HG     ET    V 
Sbjct: 226 EYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVT 285

Query: 272 ASP--KFETAQLTETAETSPL-PWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLV 328
                KF      +  +   L  W         ++Q D+ P + +L+G+  P N++G+L 
Sbjct: 286 WGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILP 345

Query: 329 SQMLGLWSPEDQLNVLKNNADQMVQILQGQASRESDAK--EVYELYD 373
              L       +   +  NA Q+++  + + +++ +A    ++  + 
Sbjct: 346 VGYLNNTGLF-KAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFK 391
>ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) biosynthesis; Gpi13p
           [Saccharomyces cerevisiae]
 pir||S64782 probable membrane protein YLL031c - yeast (Saccharomyces
           cerevisiae)
 emb|CAA97480.1| (Z73136) ORF YLL031c [Saccharomyces cerevisiae]
          Length = 1017

 Score =  422 bits (1076), Expect = e-116
 Identities = 154/618 (24%), Positives = 247/618 (39%), Gaps = 89/618 (14%)

Query: 7   TLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTES--RVSTEAPFQKAIIMVVDAFRSDFA 64
            L V I +LQ  ++  F RGFL SR +L   +           F KA+I+V+DA R DFA
Sbjct: 37  ILLVFIAILQFISIAFFTRGFLLSRHVLDNISSQNETSKLPPRFNKAVILVIDALRFDFA 96

Query: 65  FSDQSNCPQLHKRINSGGAIPFTA--------------HSTPPTVTLPRIKGLTTGSTPN 110
                +    +   ++     + +               + PPT TL R+KGLTTGS P 
Sbjct: 97  IPVNESHSNYNLNYHNNILSLYDSFASDKDASSLLLKFIADPPTTTLQRLKGLTTGSLPT 156

Query: 111 FLDAVLNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLF-PGMFDDCEGTASF 169
           F+DA  N        T+  +D++L Q     + +   GDDTW+ LF P + +D     S 
Sbjct: 157 FIDAGSNF-----DGTVIEEDNFLKQLHLANKTVKFAGDDTWMALFHPFLSNDSFPLESL 211

Query: 170 FVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDI 229
            V D   VDN V  +    L Q  EWDV+I H LG+DH+GHK GP+   M  KQ ++D  
Sbjct: 212 NVWDLDTVDNGVMDYFHDHLQQDKEWDVMIGHMLGIDHVGHKYGPDHFTMREKQIQVDQF 271

Query: 230 FDKLYNSCDDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFETAQLTETAETSP 289
            D +  S DDDT+L++LGDHGM+  GNHGG S  E  + +   S K +  +L ET+    
Sbjct: 272 IDWILKSIDDDTLLVILGDHGMDHTGNHGGDSIDELESTLFLYSKKPDMWRLKETSN--- 328

Query: 290 LPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSPEDQLNVLKNNAD 349
               +    +  + Q DLV +L  L+G   P NNLG        +   + + +   N+A 
Sbjct: 329 YNIDNLGHDYRSVRQIDLVSSLALLMGQPIPFNNLG-WPID--EIARNDREWSQFVNSAI 385

Query: 350 QMVQILQGQASRESDAKEVYELY-DTLNSNPSVKDYYNFLYEAQSY-------LTHASSN 401
             +Q+ +          E+ E     +++ P   D   F+     Y            + 
Sbjct: 386 SQLQLYKDTMQIHHGNDEILEPLAKNISNTPPTSDPEKFVKLGHKYQKVFLQTCEELWAK 445

Query: 402 YNTNDMLGGIGLGLLSTILALTVFSALTLAVQGLKR-------LYLIILLVYF-ISVFGS 453
           ++   +  GI L       +L +  ++T  +  +         +  II++V      F  
Sbjct: 446 FDYYSIATGITLLAT----SLVLLISITKLIPSIVVNQMVPEFVPGIIIMVLVTNLCFHG 501

Query: 454 ST-VEEEHQIWYWITSGWMAFLYISGSRNKFGDGFNWMFVQVFVR--------------- 497
              V ++           +A                + F+ + +R               
Sbjct: 502 IFYVYQQPSFVDQFWGTLLATAIGIIIGCYITIFDRYNFIWIAMRLGETLADYWSRIAVM 561

Query: 498 --MMISWNQTGQKFTKKDDIVTWLSKDGNQPSLWILILVTYGVAFNKVWRYGFSKVESKL 555
             ++ +   T   FT  +D +               +L T+G+               + 
Sbjct: 562 FMIIHALLFTSNSFTIWEDRIVAF------------LLSTFGM-----------LTLYEF 598

Query: 556 AFLLTLITTFASVGFKIT 573
            FL    +T A +   I+
Sbjct: 599 VFLPKRQSTTALLTATIS 616
 Score =  183 bits (462), Expect = 1e-44
 Identities = 41/366 (11%), Positives = 104/366 (28%), Gaps = 74/366 (20%)

Query: 491 FVQVFVRMMIS--WNQTGQKFTKKDDIVTWLSKDGNQPSLWILILVTYGVAFNKVWRYGF 548
           F+ +F+       +      +           +      + + +    G+       +  
Sbjct: 692 FLMIFILPACITGYYNLTSSY-----------QAAAPIWINVFLKGILGL---NFVYWSL 737

Query: 549 SKVESKLAFLL-TLITTFASVGFKITQAWEAGEVVPAPLLYLMGLPGT--------LNEV 599
           + +E+  A +    +       F + +      ++ + + +LMG            +   
Sbjct: 738 TSLENNSAVIAIPFLRDVTIFKFTLARIIAGFSLIASNVGWLMGPLCIKLNIHNTDVKSH 797

Query: 600 NARMAGLARFAFSTIAAGSLYRVLSLAGTDKVNLIRDLHAFLTLFLITQSRIQNIPLFMV 659
            A + G      S      +  ++S+   +K                             
Sbjct: 798 EATILGYTNIYGSEFFLLVINVLISILLFNKPLAQ------------------------- 832

Query: 660 YYFLEIFLRKATNRSFIFSSRDIYQTEALFQKLVLVLSVSTLLLEQVSFFSMGNSNSMAS 719
              L  FL      S +     +   E       ++  ++  LL    FF+ G+  ++ S
Sbjct: 833 ---LSYFLMCNQLLSILEIIDLLKLKE------NIIGPIALGLLSYQHFFTTGHQATIPS 883

Query: 720 IDLSNAYNGVTLYQIE-FVGVLTFVSNWIGPLYWSTAGLSFLLEDHVRNAIFAKIAEKNN 778
           +     +  ++      F  +   ++ +   +  S +     L     + +         
Sbjct: 884 VQWDIGFM-LSEKVTFPFTQIAIILNTFGPHILVSLSVALLTLWSQPPDVL-KPQTLLGR 941

Query: 779 DVKLTTKLVQQALTLRVYVVLAFSSVAISAVMITCFFLREHLFIWTVFSPKLLYQFVWTV 838
            V          + L    +L  SS       I     R HL +W +F P+ ++  +  +
Sbjct: 942 IVSNCG------ILLTYNTILCLSS------FIWVTHFRRHLMVWKIFCPRFIFASLSLI 989

Query: 839 LQFALV 844
           +   +V
Sbjct: 990 VTQLVV 995
>ref|XP_082200.1| (XM_082200) CG6790 [Drosophila melanogaster]
          Length = 656

 Score =  416 bits (1059), Expect = e-115
 Identities = 83/626 (13%), Positives = 170/626 (26%), Gaps = 75/626 (11%)

Query: 255 GNHGGSSAGETSAAMVFASPKFETAQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTAL 314
           G+HGG S  E  A  +      +   +TE   +  +          ++DQ  L P ++AL
Sbjct: 19  GSHGGGSDEEREAPFLLWGAGVK--HVTENITSDFVLNNGVGMQLHKLDQIQLAPLMSAL 76

Query: 315 LGLNTPKNNLGVLVSQMLGLWSPEDQLNVLKNNADQMVQILQGQASRESDAKEVYELYDT 374
           +GL  P NNL +L    + + S E     +  NA Q++     +A      + V+  +  
Sbjct: 77  IGLPPPVNNLAILPQGYMKV-SREYARKSVHLNALQLLTQ--AKAIIRLHERGVFHKWLP 133

Query: 375 LNSNPSVKDYYNFLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTILALTVFSALTLAVQG 434
            + +  ++    +  +    L     +         I +     + +L  +         
Sbjct: 134 KDKDLDLQQIAYYQNQMDHLLDMGWRSKALETSTLAIKV----ALKSLKFYHNYYHIPLV 189

Query: 435 LKRLYLIILLVYFISVFGSSTVEEEHQ---IWYWITSGWMAFLYISGSRNKFGDGFNWMF 491
           +  +  ++   ++  V  S  V   H     +    + ++A L +      F     +M 
Sbjct: 190 VTTVLALLGWQFYQLVKLSQNVMAPHYMRRGYLTWCTIFLASLGLLLGEMVFLQWAPFMT 249

Query: 492 VQVFVRMMISWNQTGQ----------------KFTKKDDIVTWLSKDGNQPSLWILILVT 535
           V   V     W  T                  ++      V   S   N P    L L  
Sbjct: 250 VICLVVPFGVWCMTLAALPQNGGWIFEPLKHLRWIVGPAAVMIASIYCNCP----LSLAY 305

Query: 536 YGVAFNKVWRYGFSKVESKLAFLLTLITTFASVGFKITQAWEA-----GEVVPAPLLYLM 590
                    R         LA+L  ++     +  +              +    +L ++
Sbjct: 306 ILCVGFYNRRGWLHPSPKFLAWLALVLLLGGFLWSQKGMQILMTTNYRVVLQAISMLVVI 365

Query: 591 GLPGTLNEVN--------ARMAGLARF---------AFSTIAAGSLYRVLSLAGTDKVNL 633
             P  LNE +          +  +A                   + +  L  A       
Sbjct: 366 VRPCVLNENHKWKVWVINGGILFVAAIGIFLKEMGKPVPLYLFAANWAYLIYAFASVPCS 425

Query: 634 IRDLHAFLTLFLITQSRIQNIPLFMVYYFLEIFLRKATNRSFIFSSRDIYQT-------- 685
            R         +       ++ L   Y  L         +  +       +         
Sbjct: 426 SRTTPQSRLELIRFNLLTLHVLLSDSYVSLFAQGLIIEYQMGLEVHEKFKEADEDVKILT 485

Query: 686 EALFQKLVLVLSVSTLLLEQVSFFSMGNSNSMASIDLSNAYNGVTLYQIEFVGVLTFVSN 745
            +   ++    +VS LL    S F  G+     +   ++A   +       V +L  +  
Sbjct: 486 SSKHLQMCYRFAVSILLYFYASLFGTGHWVGGFTYLANSARLFLPDSSSGLVPLLVLIHL 545

Query: 746 WIGPLYWSTAGLSFLLEDHVRNAIFAKIAEKNNDVKLTTK-----------LVQQALTLR 794
            I  +    + +   L    R  I    +                            ++ 
Sbjct: 546 LIPSIVIMASVV--ALSSFGRQQIRTIFSSLMLICNAVVLFFVVFVPHNAYWPMAHPSVV 603

Query: 795 VYVVLAFSSVAISAVMITCFFLREHL 820
             ++   + + I A           L
Sbjct: 604 HALLAQLTVILILACESIVTIFFRRL 629
>ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class O [Mus musculus]
 dbj|BAA96254.1| (AB038560) Pig-o [Mus musculus]
          Length = 1101

 Score =  371 bits (944), Expect = e-101
 Identities = 138/471 (29%), Positives = 206/471 (43%), Gaps = 89/471 (18%)

Query: 1   MLWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEA-------------- 46
           +L+  W     +  L  A + LF  GFL +R+ L   +  +                   
Sbjct: 15  LLFLAW-----VCFLFYAGIALFTSGFLLTRLELTNQSSCQELPGPGPLPWGSHGKPGAC 69

Query: 47  ----PFQKAIIMVVDAFRSDFAFSDQSNCP--------------QLHKRINSGGAIP--F 86
                F + +++++DA R DFA   +S+ P               L + + S       +
Sbjct: 70  WMPSRFSRVVLVLIDALRFDFAQPQRSHVPGEPPVSVPFLGKLGSLQRILESQPHHGRLY 129

Query: 87  TAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAESDNSSTLANQDSWLAQASRDGRKIHM 146
            +   PPT T+ R+K LTTGS P F+DA  N A     S    +D+ + Q +  GR++  
Sbjct: 130 RSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFA-----SHAIVEDNVIQQLNSAGRRVVF 184

Query: 147 FGDDTWIKLFPGMFDDCEGTASFFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLD 206
            GDDTW  LFPG F      +SF V D   VDN +  H+   LD    WDVLI H+LG+D
Sbjct: 185 MGDDTWRDLFPGAFSQAFFFSSFNVRDLHTVDNGILEHLYPTLDG-GSWDVLIAHFLGVD 243

Query: 207 HIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDTVLILLGDHGMNEVGNHGGSSAGETS 266
           H GHK GP  P M  K  +MD +   L    ++DT+L++ GDHGM   G+HGG S  E S
Sbjct: 244 HCGHKHGPHHPEMAKKLSQMDQVIQGLIERLENDTLLVVAGDHGMTMNGDHGGDSELEVS 303

Query: 267 AAMVFASPKFETAQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGV 326
           AA+   SP   TA         P            + Q  LVPTL  LLGL  P  N G 
Sbjct: 304 AALFLYSP---TALFPSVPPEEP----------EVIPQVSLVPTLALLLGLPIPFGNTGE 350

Query: 327 LVSQMLGLWSPED--------QLNVLKNNADQMVQILQGQA--SRESDAKEVYELYDTLN 376
           +++++    S           Q++ L  NA Q+ + L   +  +++   KE++ L  TL 
Sbjct: 351 VMAELFSGGSDSSHPHSSALAQVSALHINAQQVSRFLHTYSAATQDLQVKELHRL-QTLF 409

Query: 377 SNPSVK--------------------DYYNFLYEAQSYLTHASSNYNTNDM 407
           S  S +                    ++  FL  A++    + + ++   M
Sbjct: 410 SKASARYQHFLRDPQEAEAALSTLTAEFQQFLRGARALCIESWARFSLVRM 460
 Score =  190 bits (480), Expect = 7e-47
 Identities = 40/299 (13%), Positives = 83/299 (27%), Gaps = 53/299 (17%)

Query: 592  LPGTLNEVNA--------RMAGLARFAFSTIAAGSLYRVLSLAGTDKVNLIRDLHAFLTL 643
            +   +             R         +    GS+Y    +     +     L     +
Sbjct: 805  VVPQIYRHMQEEFQGRLERTKAQGPITVAAYQLGSVYSAAMVTALLLLAFPLMLLHVERV 864

Query: 644  FLITQSRIQNIPLFMVYYFLEIFLRKATNRSFIFSSRDIYQTEALFQKLVLVLSVSTLLL 703
             L+         L +            T  +       ++Q  +           + +LL
Sbjct: 865  SLVFLLLFLQSFLLLHLLAAG------TPVATPGPFTVLWQAVS-----------AWVLL 907

Query: 704  EQVSFFSMGNSNSMASIDLSNAYNGVTLYQIE---FVGVLTFVSNWIGPLYWSTAGLSFL 760
               +F+S G+    ++I    A+ G             +L   + +   L ++      L
Sbjct: 908  ATQTFYSTGHQPVFSAIHWHAAFVGFPDGHGSSTWLPALLVGANTFASHLLFAVGCPLLL 967

Query: 761  LEDH--VRNAIFAKIAEKNNDVKL--------------TTKLVQQALTLRVYV------- 797
            L      R     +     ++ +                   ++ A              
Sbjct: 968  LWPFLCERQGPKRRQPLPGSESEARVRPEEEEELQEPLMEVRLRDAPNHFNAALLQLGLK 1027

Query: 798  VLAFSSVAISAVMITCFFLREHLFIWTVFSPKLLYQFVWTVLQFALVDVILSSIFVVLV 856
             L      I A  +    LR HL +W VF+PK +++ V  ++    V ++L    V+ V
Sbjct: 1028 YLFILGAQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSS--VGLLLGIALVMRV 1084
>ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans]
          Length = 348

 Score =  352 bits (896), Expect = 1e-95
 Identities = 80/378 (21%), Positives = 137/378 (36%), Gaps = 56/378 (14%)

Query: 1   MLWKRWT--LAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESR-VSTEAPFQKAIIMVVD 57
           M WK     + V +V++     + +         L+ G       S EAP ++  I+  D
Sbjct: 1   MSWKFLIASITVHLVLIYSIFDVYYTS------PLVHGIPPQFINSQEAPAKRIFIISAD 54

Query: 58  AFRSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLN 117
             R D         P LH  +N    I   + S  PT + P    +  G T +    +  
Sbjct: 55  GLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITED----ISA 110

Query: 118 IAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTAS-----FFVS 172
           +A+    + +   DS   ++S       M+G    + LF  + +    + S     F   
Sbjct: 111 VAKGWKKNPV-QFDSVFNRSSYSW----MWGSPDIVNLFDDLPNAESFSYSADEEDFASK 165

Query: 173 DYTEVDNNVTRHIDTQL-----------DQKTEWDVLILHYLGLDHIGHKTGPESPFMPA 221
           D + +D  V  H +  L             + +  +  LH LG+D  GH   P S     
Sbjct: 166 DASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYID 225

Query: 222 KQKEMDDIFDKLYNSC-----DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKF 276
             K +D   +K+ +       D  T  +   DHGM + G+HG  S  E     V      
Sbjct: 226 NIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGV 285

Query: 277 ETAQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWS 336
           +                        ++Q DL P ++AL+G   P N++G+L  QM+    
Sbjct: 286 KQGGPK-----------------LDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKG 328

Query: 337 PEDQLNVLKNNADQMVQI 354
              +   ++ N  Q++ +
Sbjct: 329 SSYEFKAIEANFKQVINL 346
>gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melanogaster]
          Length = 880

 Score =  344 bits (874), Expect = 5e-93
 Identities = 140/576 (24%), Positives = 230/576 (39%), Gaps = 105/576 (18%)

Query: 4   KRWTL-AVTIVVLQLAAVLLFARGFLPSRVLL-------------PGYTESRVSTEAPFQ 49
           K W +  + ++   L   +LF  GF P+   +                          + 
Sbjct: 5   KSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYD 64

Query: 50  KAIIMVVDAFRSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTP 109
             ++++VDA R DF   D ++ P  + R           H   PTVT+PR+K +TTG+  
Sbjct: 65  SFVLLLVDALRDDF--PDATSMPVAYSRACE----KLKLHVDIPTVTMPRLKSITTGTLS 118

Query: 110 NFLDAVLNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDD-CEGTAS 168
           NF+D  LN+  ++       QDS+L +  +  R +   GD TW+KLFP  F    E   S
Sbjct: 119 NFIDIALNVGHTEQM-----QDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDS 173

Query: 169 FFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDD 228
           F+V+D+ E D NVT+ ++T+L ++++W +LILHYLGLDHIGH  G  SP +P K KEMD+
Sbjct: 174 FYVNDFYEGDRNVTKTLETEL-ERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDE 232

Query: 229 IFDKLYNSCDDDT----VLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFETAQLTET 284
           +  K+    D  +    +L+L GDHGM + G HGG++  ET   +               
Sbjct: 233 VVKKI---LDHKSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLY------------ 277

Query: 285 AETSPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSPEDQLNVL 344
                   T +       +Q DL PTL+ LL +  P  ++G L+ +ML   S E QL   
Sbjct: 278 YNN--CSKTPSASKRY--NQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAY 333

Query: 345 KNNADQMVQILQGQ----ASRESDAKEVYELYDTLNSNP--------------------- 379
             NA  ++   + +        SD    Y+    L+                        
Sbjct: 334 FYNAHHLLNKARVKFGHEIVHRSDYYTWYQNATLLHKKLLRPLREGDGGGASQVYYQNAK 393

Query: 380 --SVKDYYNFLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTILALTVFSA---------- 427
              ++   + L   Q +L+  ++            +   ST+ ++ +             
Sbjct: 394 LNYMRLQLDGLKVGQLWLSVIAAVVLNYTSHALDIIMTSSTLYSILLLVPISIAVYLTID 453

Query: 428 -------------LTLAVQGLKRLYLIILLVYFI---SVFGSSTVEEEHQIWYWITSGWM 471
                         T  ++    L L +L  Y I   ++  SS +E E+  WY++ +  +
Sbjct: 454 VAQALLKIALPPLYTRRLKISIPLPLPLLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLI 513

Query: 472 AFLYISGSRNKF-GDGFNWM-FVQVFVRMMISWNQT 505
                   R +               +     W   
Sbjct: 514 LLTAFRTLRWRITKTNVELNGRHLYTIASTCLWQMR 549
>ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thaliana]
 gb|AAF18652.1| (AC006592) unknown protein [Arabidopsis thaliana]
          Length = 897

 Score =  332 bits (845), Expect = 1e-89
 Identities = 134/391 (34%), Positives = 195/391 (49%), Gaps = 51/391 (13%)

Query: 6   WTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEA---------------PFQ- 49
               V  ++LQ+  + +F  GF P +  L G + S    +                P + 
Sbjct: 12  TIFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKL 71

Query: 50  KAIIMVVDAFRSDFAFSD---------QSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRI 100
           + +  V+D   ++F             + + P     + +G AI + A + PPTVT+PR+
Sbjct: 72  RLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRL 131

Query: 101 KGLTTGSTPNFLDAVLNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMF 160
           K + +G+   FLD   N     N+  L + D+ L Q  R G K+ M GD+TW+KLFPG+F
Sbjct: 132 KAMVSGAIGGFLDVAFNF----NTQALLD-DNILGQFFRIGWKMVMLGDETWLKLFPGLF 186

Query: 161 DDCEGTASFFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLDHIGHKTGPESPFMP 220
              +G +SFFV D  +VD NV+RH+  +L+   +W++LILHYLGLDH+GH  G  SP MP
Sbjct: 187 MRHDGVSSFFVKDTVQVDRNVSRHLPDELNSD-DWNLLILHYLGLDHVGHTGGRNSPLMP 245

Query: 221 AKQKEMDDIFDKLYNSCDDD-------TVLILLGDHGMNEVGNHGGSSAGETSAAMVFAS 273
           AK KEMDDI   ++     D       T+LI++ DHGM E GNHGGSS  ET + M+F  
Sbjct: 246 AKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLMLFIG 305

Query: 274 PKFETAQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLG 333
                +                        Q DL PTL  L G+  PKNN+GVLV   L 
Sbjct: 306 LNSNISDYASATNNVAF-------------QVDLAPTLALLFGVPIPKNNVGVLVPGTLC 352

Query: 334 LWSPEDQLNVLKNNADQMVQILQGQASRESD 364
                +QL  L+ N+ Q+++++  Q    S 
Sbjct: 353 SLRDFEQLRALELNSWQLLRLMLAQIQSSSF 383
 Score =  238 bits (603), Expect = 3e-61
 Identities = 75/468 (16%), Positives = 148/468 (31%), Gaps = 64/468 (13%)

Query: 338 EDQLNVLKNNADQMVQILQGQASRESDAKEVYELYDTLNSNPSVKDYYNFLYEAQSYLTH 397
           E QL  L  NA                 K         + + ++  Y  FL  A  +L  
Sbjct: 411 EKQLICLFRNA-------AALHGIWKSKKSTESSSTMEDFSRALDAYNTFLKTASEWLAS 463

Query: 398 ASSNYNTNDM-LGGIGLGLLSTILALTVFS--------------ALTLAVQGLKRLYLII 442
            ++      + LG   + L   I      S              +L+  +   +     +
Sbjct: 464 KTTEKPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFIFAL 523

Query: 443 LLVYFISVFGSSTVEEEHQIWYWITSGWMAFLYISGSR-------NKFGDGFNW---MFV 492
           LL+  IS+  SS VEEEH IW+++ S +   L    ++             F +     +
Sbjct: 524 LLILVISMGSSSMVEEEHYIWHFMVSTFHLLLLFKTAKSFKISKGMNILRDFKFGSIFSL 583

Query: 493 QVFVRMMISWNQTGQKFTKKDDIVTWLSKDGNQPSLWILILVTYGVA----FNKVWRYGF 548
            +  R++  W+Q G  +T   DI  WL + G+    WI ++    V     +        
Sbjct: 584 LISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLISIILVIGLGLYTLFRTGSN 643

Query: 549 SKVESKLAFLLTLITTFASVGFKITQAWEAGEVVPAPLLYLMGLPGTLNEVNARMAGLAR 608
            K    LAF                            +L  +G      +        A 
Sbjct: 644 RKGVRILAF--------------------GFSTCGFLVLLHVGR----YQDELSTGFGAT 679

Query: 609 FAFST-IAAGSLYRVLSLAGTDKVNLIRDLHAF-LTLFLITQSRIQNIPLFM--VYYFLE 664
                     S+  + +        L +D          +       I  +        +
Sbjct: 680 VTVKVIYYLLSISSIGASLVLPWSALNKDKSFLAEVGDCLYLIGSAYILCWCLLQQLLQQ 739

Query: 665 IFLRKATNRSFIFSSRDIYQTEALFQKLVLVLSVSTLLLEQVSFFSMGNSNSMASIDLSN 724
                      +     +  + + FQ    V   +   +     F++GNSN++A+ID++ 
Sbjct: 740 PINSGPILLLLLQILAILCLSSSDFQVNEWVEITALYYMGMAGHFALGNSNTLATIDVAG 799

Query: 725 AYNGVTLYQIEFVGVLTFVSNWIGPLYWSTAGLSFLLEDHVRNAIFAK 772
           A+ G++ +     G+L F+  +  P+ +  + + ++  +   ++    
Sbjct: 800 AFIGISSHSTILSGILMFMITYASPMLFLLSLVMYIGANLRNHSNSTI 847
>dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:1351629,
           evidence:ISS~phosphatidylinositol glycan, class
           N~putative [Mus musculus]
          Length = 320

 Score =  321 bits (817), Expect = 2e-86
 Identities = 69/325 (21%), Positives = 108/325 (33%), Gaps = 47/325 (14%)

Query: 1   MLWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFR 60
           +L+    L +  V       + F         L+ G T        P ++ ++ V D  R
Sbjct: 2   LLFFALGLLIHFVFFASIFDIYFTS------PLVHGMTPQFTPLPPPAKRLVLFVADGLR 55

Query: 61  SDFAFS----DQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVL 116
           +D  +       S  P +   I   G+    +H+  PT + P    L  G   +    V 
Sbjct: 56  ADTLYELDEDGNSRAPFIRNVIMHEGSWG-VSHTRVPTESRPGHVALIAGFYED----VS 110

Query: 117 NIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFP-GMFDDCEGTAS------- 168
            +A+    + +   DS   +          +G    + +F  G   D   T S       
Sbjct: 111 AVAKGWKENPV-ESDSLFNERKYTW----SWGSPDILPMFAKGASGDHVYTYSYDAQRED 165

Query: 169 FFVSDYTEVDNNVTRHIDTQLDQK-----------TEWDVLILHYLGLDHIGHKTGPESP 217
           F   D T++D  V   +    D              E  V  LH LG+D  GH   P S 
Sbjct: 166 FGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSR 225

Query: 218 FMPAKQKEMDDIFDKLYNSC------DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVF 271
                 K++DD   ++ +        D  T  I   DHGM + G+HG     ET    V 
Sbjct: 226 EYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVT 285

Query: 272 ASP--KFETAQLTETAETSPLPWTD 294
                KF      +  +   L  T+
Sbjct: 286 WGAGIKFPQNVSAQQYDDEFLKGTN 310
>gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melanogaster]
          Length = 1077

 Score =  304 bits (772), Expect = 4e-81
 Identities = 106/398 (26%), Positives = 168/398 (41%), Gaps = 64/398 (16%)

Query: 46  APFQKAIIMVVDAFRSDF-AFSDQ--SNCPQLHKRI--------NSGGAIPFTAHSTPPT 94
               K I++VVDA + +F  +        P  +K +        N   A      + PPT
Sbjct: 74  PQKSKVIVLVVDALKYEFGLYRANATDPLPYENKLVVLQELLQQNPDHARLMRFRADPPT 133

Query: 95  VTLPRIKGLTTGSTPNFLDAVLNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIK 154
            TL R+KGLTTGS P F+D   N A     S   N+D+ + Q  ++   +   GD TW  
Sbjct: 134 TTLQRLKGLTTGSLPTFIDIGSNFA-----SPEINEDNIIDQIVKNDLPVVFLGDSTWTD 188

Query: 155 LFPGMFDDCEGTASFFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLDHIGHKTGP 214
           L+P  F       SF + D   VDN + +H+  +L+ K +W VL+ H+LG+DH GHK GP
Sbjct: 189 LYPHRFKRSYSYPSFDIFDLDSVDNEILKHLPKELESK-DWQVLVAHFLGVDHCGHKHGP 247

Query: 215 ESPFMPAKQKEMDDIFDKLYNSCDDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASP 274
               M  K  EM+++   +  + D+DT L+++GDHGM   G+HGG +  ET+A +   S 
Sbjct: 248 MHEEMARKLGEMNEVIRSVVAAMDNDTTLLVMGDHGMTASGDHGGDTDDETNALLFAYS- 306

Query: 275 KFETAQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGL 334
           K       ++   S             + Q DLVPTL  +LG+  P +NLG++      +
Sbjct: 307 KQHRFYGNDSGSDS-----------EMLQQIDLVPTLATILGVPIPYSNLGLVN---FNI 352

Query: 335 WSPEDQLNVLKNNADQMV-----------------------QILQGQASRESDAKEVY-- 369
                 L V   N  Q +                       +    +     + + +   
Sbjct: 353 VPD---LRVPHLNKFQTLLLHSWQNAQQIYRYFFQYALENKRTFNVEQMDHLETEFILLT 409

Query: 370 ----ELYDTLNSNPSVKDYYNFLYEAQSYLTHASSNYN 403
                +Y+ +     V+D    L +           ++
Sbjct: 410 HRVQTVYNEVAFKSFVRDLNTNLRDILGTCREIWVRFD 447
 Score =  224 bits (567), Expect = 5e-57
 Identities = 49/350 (14%), Positives = 104/350 (29%), Gaps = 60/350 (17%)

Query: 546  YGFSKVESKLAFLLTLITTFASVGFKITQAWEAGEVVPAPLLYLMGLPGTLNEVNARMAG 605
            YG   V+  +     L+T         T      E +   +   M      ++   R   
Sbjct: 740  YGLLLVQIIVLSWAPLMTFVLPPRSSHTVTINGNESIVPEIFRKMKRMYEGDDDERR--- 796

Query: 606  LARFAFSTIAAGSLYRVLSLAGTDKVNLIRDLHAFLTLFLITQSRIQNIPLFMVYYFLEI 665
                        ++Y  + +A                + ++      +I L +V   +  
Sbjct: 797  --SHIPVVYGLATVYSSIVIAFG---------VFLALVMIVLLEPRASIGL-VVCVAVGA 844

Query: 666  FLRKATNRSF-IFSSRDIYQTEALFQKLVLVLSVSTLLLEQVSFFSMGNSNSMASIDLSN 724
             L    +      ++      +  F  L     V   LL    FF+  +  +++ I+   
Sbjct: 845  ILLSVHSILRYRTATSFESCVQPTFTAL-----VGWFLLAHFCFFATSHQTTLSQIEWRA 899

Query: 725  AYNGVTLY---QIEFVGVLTFVSNWIGPLYWSTAGLSFLLEDHVRNAIFAKIAEKNNDVK 781
            A+ G T          G L  ++ + GP+++    +  LL      ++FA         +
Sbjct: 900  AFVGRTTGIGQSNLVSGALVILNTFCGPIFF--FCMYSLLSTETF-SLFALFPNLIRSCR 956

Query: 782  LTT-------------------KLVQQALTLRV------------YVVLAFSSVAISAVM 810
                                      +                          + I   M
Sbjct: 957  SGGKVDASTSMSDLANEAVGFDMTRGELSLYEYEDVFLGTGFKLATQFFMLQGLKIFCAM 1016

Query: 811  ITCFFLREHLFIWTVFSPKLLYQFVWTVLQFALVDVILSSIFVVLVYRSV 860
            + C     HL +W +F+P+ +Y+ + T +   L  +I+  + V+ ++R V
Sbjct: 1017 LACTIHCRHLMVWKIFAPRFIYEALATFVS--LPALIVGYLLVLRIHRGV 1064
>ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thaliana]
 dbj|BAB10512.1| (AB005238) gene_id:MKP11.10~unknown protein [Arabidopsis thaliana]
          Length = 884

 Score =  284 bits (721), Expect = 4e-75
 Identities = 74/456 (16%), Positives = 138/456 (30%), Gaps = 73/456 (16%)

Query: 451 FGSSTVEEEHQIWYWITSGWMAFLYISGSRNKFGDGFNWMFVQVFVRMMISWNQTGQKFT 510
           F SS VE     W       M   +     +     F  +F       + SW  TG  FT
Sbjct: 447 FFSSVVELARSKWTEFNLNLMITGFGILVISLILQ-FLAVFHGDKSYAVGSWLSTGAAFT 505

Query: 511 KKDDIVTWLSKDGNQPS-----LWILILVTYGVA---FNKVWRYGFSKVESKLA--FLLT 560
                +   S   N        +   +L T G+    ++ + +    +    LA  F+L 
Sbjct: 506 LFIVTIRACSFLSNSYILEEGKVANFLLATTGLIKLRYSVMRKTMRKEAFMFLAMVFVLR 565

Query: 561 LI-----------TTFASVGFKITQAWEAGEVV------PAPLLYLMGLPGTLN------ 597
           +            + F S                      AP+L ++ L   L       
Sbjct: 566 VSIDIGLTKQAATSQFMSSSPSWMLGIAPDHPALTYAIEIAPILSVVILICVLYVAIAKA 625

Query: 598 -------------EVNARMAGLARFAFSTIAAGSL--YRVLSLAGT------DKVNLIRD 636
                         +     G  R   +    G +    + S          +       
Sbjct: 626 PNEGVWKYVTVGSMLLQVTGGRNRIPQTVYVIGLVQLCLLASARMFCTEKDKNWAIRTVA 685

Query: 637 LHAFLTLFLITQSRIQNIPLFMVYYFLEIFLRKATNRSFIFSSRDIYQTEALFQKLVLVL 696
           L +  +  +I  S  Q   L +VY      + +         S      ++ F KL  + 
Sbjct: 686 LVSACSSPIILLSGKQGSMLALVYLVAGYCIMRLEGVERRTKSD----GQSKFSKLNPLC 741

Query: 697 SVSTLLLEQVSFFSMGNSNSMASIDLSNAYNGVTLYQIEFVGVLTFVSNWIGPLYWSTAG 756
            V   LL    FF+ G+  +   +    A+ G   + +    +L  +  +   +  S  G
Sbjct: 742 VVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLIRQAILLTIETFGFSIILSVFG 801

Query: 757 LSFLLEDHVRNAIFAKIAEKNNDVKLTTKLVQQALTLRVYVVLAFSSVAISAVMITCFFL 816
           L  L            I   +   +   +   Q   +   +    S+  ++A ++     
Sbjct: 802 LPLL------------IPFHSQTPQAHGEKRHQLFQM-YMLFGVISATTVTATILCVTIQ 848

Query: 817 REHLFIWTVFSPKLLYQFVWTVLQFALVDVILSSIF 852
           R HL +W +F+PK ++  V  +L   L+  + S+ +
Sbjct: 849 RRHLMVWGLFAPKFVFDVVDLILTDLLI-CLASAYY 883
 Score =  230 bits (581), Expect = 1e-58
 Identities = 78/229 (34%), Positives = 113/229 (49%), Gaps = 15/229 (6%)

Query: 79  NSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAESDNSSTLANQDSWLAQAS 138
           N   A  F A + PPT +L R+KGLTTG  P F+D   +            +D+++ Q  
Sbjct: 82  NDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSFGA-----PAIVEDNFINQLV 136

Query: 139 RDGRKIHMFGDDTWIKLFPGMFDDCEGTASFFVSDYTEVDNNVTRHIDTQLDQKTEWDVL 198
            +G+++ M GDDTW +LFP  F       SF V D   VDN    H+   L +  +WDVL
Sbjct: 137 LNGKRLVMMGDDTWTQLFPNQFQKSYPFPSFNVKDLDTVDNGCIEHLFPTLFKD-DWDVL 195

Query: 199 ILHYLGLDHIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDD---------DTVLILLGDH 249
           I H+LG+DH GH  G +S  M  K ++ + + +K+ N  +          +T+LI++GDH
Sbjct: 196 IAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDH 255

Query: 250 GMNEVGNHGGSSAGETSAAMVFASPKFETAQLTETAETSPLPWTDTYKY 298
           G    G+HGG +A E    M   S K  T  +    +TS        K 
Sbjct: 256 GQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDTSSCKQNKDGKQ 304
 Score = 34.9 bits (80), Expect = 5.4
 Identities = 23/128 (17%), Positives = 46/128 (34%), Gaps = 8/128 (6%)

Query: 378 NPSVKDYYNFLYEAQSYLTHASSNYNTNDMLGGIGLG-LLSTILALTVFSALTLAVQGLK 436
              + +Y NF            + +N N M+ G G+  +   +  L VF        G  
Sbjct: 438 KEQIAEYLNFFSSVVELARSKWTEFNLNLMITGFGILVISLILQFLAVFHGDKSYAVGSW 497

Query: 437 R-----LYLIILLVYFISVFGSSTVEEEHQI--WYWITSGWMAFLYISGSRNKFGDGFNW 489
                   L I+ +   S   +S + EE ++  +   T+G +   Y    +    + F +
Sbjct: 498 LSTGAAFTLFIVTIRACSFLSNSYILEEGKVANFLLATTGLIKLRYSVMRKTMRKEAFMF 557

Query: 490 MFVQVFVR 497
           + +   +R
Sbjct: 558 LAMVFVLR 565
>gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophosphatase [Arabidopsis
           thaliana]
          Length = 456

 Score =  256 bits (648), Expect = 2e-66
 Identities = 54/278 (19%), Positives = 96/278 (34%), Gaps = 31/278 (11%)

Query: 1   MLWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKA-----IIMV 55
           ML+    L+ + ++  + A +  A         L     S+     PF+K      +++ 
Sbjct: 1   MLFLSNFLSSSFLIFFIVATIAAAAAVNAGTKGLDSR-PSKTRRPWPFKKLNKPVVLMIS 59

Query: 56  VDAFRSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAV 115
            D FR  + F  +++ P +   I+ G           PT+T P    + TG  P +   +
Sbjct: 60  CDGFRFGYQF--KTDTPNIDLLISGGTEAKHGLIPVFPTMTFPNHYSIATGLYPAYHGII 117

Query: 116 LNIAESDNSSTLAN----QDSWLAQASRDGRKIHMFGDDTWIKLFPGM---------FDD 162
           +N      +  + N       WL +           G       +P            + 
Sbjct: 118 MNKFTDPVTGEVFNKGLQPKWWLGE--PLWVTAVNQGLKAVTYFWPSSEVLKSSWTCPEG 175

Query: 163 CEGTASFFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLDHIGHKTGPESPFMPAK 222
                +  V     VD+ V  H D    +    D+L+L++   D  GH  GP+ P +   
Sbjct: 176 YCPHFNLSVPLEERVDS-VLSHFDHL--EDEVPDLLMLYFDEPDQSGHNYGPDDPRVTTA 232

Query: 223 QKEMDDIFDKLYNSCDDDTVL-----ILLGDHGMNEVG 255
              +D +  ++        +      ILLGDHGM    
Sbjct: 233 VSRVDKMIGRVIKGLKQREIFDEVHVILLGDHGMVTNC 270
>dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like protein [Spinacia
           oleracea]
          Length = 479

 Score =  249 bits (632), Expect = 1e-64
 Identities = 51/273 (18%), Positives = 91/273 (32%), Gaps = 30/273 (10%)

Query: 3   WKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFRSD 62
           +     AV+   L L+A    A      ++     +        P    I++  D FR  
Sbjct: 52  FTAVIAAVSFAFLFLSATSAAAGESKTIKITTTARSL--TKLTHPI--VILISSDGFRFG 107

Query: 63  FAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAESD 122
           + F  ++  P +H+ IN+G +         PT+T P    + TG  P     + N     
Sbjct: 108 YQF--KAPTPNIHRLINNGTSAELGLIPVFPTLTFPNHYSIVTGLYPPHHGIINNYFVDP 165

Query: 123 -----NSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGM---------FDDCEGTAS 168
                 S        WL +       +   G       +PG            +     +
Sbjct: 166 ITGDKFSMASHEPKWWLGE--PLWETVAKHGKKAATYFWPGSEVIKPDWDCPSNYCIHYN 223

Query: 169 FFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDD 228
             +     VD  V  + D  ++       + L++   DH GH+ GP+ P +      +D 
Sbjct: 224 GSIPFEERVDT-VISYFDLPIN--EIPVFMTLYFEDPDHQGHQVGPDDPEITQAVINIDK 280

Query: 229 IFDKLYNSCDDDTVL-----ILLGDHGMNEVGN 256
           +  +L    +   V       ++GDHGM    +
Sbjct: 281 MIGRLIKGLEKRGVFEDVNIFMVGDHGMVGTCD 313
>ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like protein [Arabidopsis
           thaliana]
 pir||T09933 nucleotide pyrophosphatase homolog T16L4.210 - Arabidopsis thaliana
 emb|CAB45330.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79728.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 461

 Score =  249 bits (630), Expect = 2e-64
 Identities = 52/270 (19%), Positives = 93/270 (34%), Gaps = 31/270 (11%)

Query: 9   AVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKA-----IIMVVDAFRSDF 63
            + ++ + + A +  A         L     S+     PF+K      +++  D FR  +
Sbjct: 14  LIFLLNIFIVATIAAAAAVNAGTKGLDSR-PSKTRRPWPFKKLNKPVVLMISCDGFRFGY 72

Query: 64  AFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAESDN 123
            F  +++ P +   I+ G           PT+T P    + TG  P +   ++N      
Sbjct: 73  QF--KTDTPNIDLLISGGTEAKHGLIPVFPTMTFPNHYSIATGLYPAYHGIIMNKFTDPV 130

Query: 124 SSTLAN----QDSWLAQASRDGRKIHMFGDDTWIKLFPGM---------FDDCEGTASFF 170
           +  + N       WL +           G       +PG           +      +  
Sbjct: 131 TGEVFNKGLQPKWWLGE--PLWVTAVNQGLKAVTYFWPGSEVLKSSWTCPEGYCPHFNLS 188

Query: 171 VSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIF 230
           V     VD+ V  H D    +    D+L+L++   D  GH  GP+ P +      +D + 
Sbjct: 189 VPLEERVDS-VLSHFDHL--EDEVPDLLMLYFDEPDQSGHNYGPDDPRVTTAVSRVDKMI 245

Query: 231 DKLYNSCDDDTVL-----ILLGDHGMNEVG 255
            ++        +      ILLGDHGM    
Sbjct: 246 GRVIKGLKQREIFDEVHVILLGDHGMVTNC 275
>ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09931 nucleotide pyrophosphatase homolog T16L4.190 - Arabidopsis thaliana
 emb|CAB45328.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79726.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 496

 Score =  245 bits (620), Expect = 3e-63
 Identities = 51/283 (18%), Positives = 98/283 (34%), Gaps = 36/283 (12%)

Query: 3   WKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVS-----TEAPFQKA-----I 52
           +   +L +   +   AA       F   + +L     S+          P +K      +
Sbjct: 51  FIFTSLLLVTCIALSAASAFAFLFFSSQKPVLSLNQISKSPAFDRSVARPLKKLDKPVVL 110

Query: 53  IMVVDAFRSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFL 112
           ++  D FR  + F  ++  P +H+ I +G           PT+T P    + TG  P + 
Sbjct: 111 LISSDGFRFGYQF--KTKLPSIHRLIANGTEAETGLIPVFPTLTFPNHYSIVTGLYPAYH 168

Query: 113 DAVLNIAESD-----NSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFP------GMFD 161
             + N           +      + WL +       +   G       +P      G ++
Sbjct: 169 GIINNHFVDPETGNVFTMASHEPEWWLGE--PLWETVVNQGLKAATYFWPGSEVHKGSWN 226

Query: 162 DCEG---TASFFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLDHIGHKTGPESPF 218
             +G     +  V     VD  +  + D  L        + L++   DH GH+ GP+ P 
Sbjct: 227 CPQGLCQNYNGSVPFDDRVDT-ILSYFD--LPSNEIPSFMTLYFEDPDHQGHQVGPDDPQ 283

Query: 219 MPAKQKEMDDIFDKLYNSCDDDTVL-----ILLGDHGMNEVGN 256
           +      +D +  +L +  +   +      I++GDHGM    +
Sbjct: 284 ITEAVVNIDRLIGRLIDGLEKRGIFEDVTMIMVGDHGMVGTCD 326
>ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09932 nucleotide pyrophosphatase homolog T16L4.200 - Arabidopsis thaliana
 emb|CAB45329.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79727.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 457

 Score =  239 bits (604), Expect = 2e-61
 Identities = 48/236 (20%), Positives = 85/236 (35%), Gaps = 30/236 (12%)

Query: 44  TEAPFQK----AIIMVVDAFRSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPR 99
            + P +      +++  D FR  + F  ++  P +   I+ G           PT+T P 
Sbjct: 46  PQPPKKLNKPVVLLISCDGFRFGYQF--KTETPNIDLLISRGTEAKTGLIPVFPTMTFPN 103

Query: 100 IKGLTTGSTPNFLDAVLNIAESDNSSTLA----NQDSWLAQASRDGRKIHMFGDDTWIKL 155
              + TG  P     ++N      S  L     N   WL +           G       
Sbjct: 104 HYSIATGLYPASHGIIMNKFTDPVSGELFNRNLNPKWWLGE--PLWVTAVNQGLMAATYF 161

Query: 156 FP------GMFDDCEGT----ASFFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGL 205
           +P      G ++  +G      +  V     VD  +  + D  L ++   D + L++   
Sbjct: 162 WPGADVHKGSWNCPKGFCKAPYNVSVPLEERVDT-ILNYFD--LPEREIPDFMALYFDEP 218

Query: 206 DHIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDTVL-----ILLGDHGMNEVGN 256
           D  GH+ GP+ P +     ++D +  ++    +   V      ILLGDHGM    +
Sbjct: 219 DIQGHEYGPDDPRVTEAVSKVDKMIGRIIMGLEKRKVFSDVHVILLGDHGMVTNCD 274
>pir||T33724 hypothetical protein - Zymomonas mobilis
 gb|AAC70363.1| (AF086791) unknown [Zymomonas mobilis]
          Length = 429

 Score =  237 bits (599), Expect = 7e-61
 Identities = 50/278 (17%), Positives = 97/278 (33%), Gaps = 46/278 (16%)

Query: 3   WKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFRSD 62
           W    L+   ++L  A + +     + +   +   +  +          I++ +D FR+D
Sbjct: 14  WISGILS---LLLGCAGLSVVHSDAIAATAHVTAQS--KTP-------LILISIDGFRAD 61

Query: 63  FAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAESD 122
           +    +   P L   +   G+     H + P++T P    L TG  P+    V N    +
Sbjct: 62  YI--KRGLTPNLVS-LAENGSYAKVMHPSFPSITFPNHYTLVTGLYPDHHGIVGN----N 114

Query: 123 NSSTLANQDS--------------WLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTAS 168
                   DS              W  +           G  +    +PG   D EG   
Sbjct: 115 MDDAHITPDSHFKMSDHQAATDRRWWDEGEPLWVTAEKQGVVSATMFWPGSEADIEGVRP 174

Query: 169 FFVSDYTEVDNNV--TRHID-----TQLDQKTEWDVLILHYLGLDHIGHKTGPESPFMPA 221
                + + D++V  +  +D         +K     + L++  +DH GH  GP+S  +  
Sbjct: 175 EM---WRQFDSHVPFSERVDQVFSWLAYPKKKRPQFITLYFENVDHAGHLYGPDSQEVND 231

Query: 222 KQKEMDDIFDKLYNSCDDDTV---LILLGDHGMNEVGN 256
              ++D    +L        +   L+++ DHGM    +
Sbjct: 232 NLVKIDQTIGQLVQGLKQRGIKANLVIVSDHGMAATSS 269
>pir||T03293 nucleotide pyrophosphatase homolog - rice
 gb|AAA67067.1| (U25430) nucleotide pyrophosphatase precursor [Oryza sativa]
 gb|AAF65458.1|AF245483_1 (AF245483) OSE4 [Oryza sativa]
 dbj|BAB56086.1| (AP003244) nucleotide pyrophosphatase homolog [Oryza sativa]
          Length = 479

 Score =  232 bits (587), Expect = 2e-59
 Identities = 54/270 (20%), Positives = 92/270 (34%), Gaps = 36/270 (13%)

Query: 14  VLQLAAVLLFARGFLPSRVLLPGY--------TESRVSTEAPFQKAIIMVVDAFRSDFAF 65
           +L  AA+ +     L      P            ++V  E P    I++  D FR  +  
Sbjct: 49  LLLTAALAVATSYLLLILPRTPLSAAPAPAAAARAQVKLEKPV--VILISSDGFRFGYQH 106

Query: 66  SDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAESD--- 122
             ++  P +H+ I +G +         PT+T P    + TG  P+    + N        
Sbjct: 107 --KAATPHIHRLIGNGTSAATGLVPIFPTLTFPNHYSIATGLYPSSHGIINNYFPDPISG 164

Query: 123 --NSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGM---------FDDCEGTASFFV 171
              + +      WL +           G       +PG           D      +  V
Sbjct: 165 DYFTMSSHEPKWWLGE--PLWVTAADQGIQAATYFWPGSEVKKGSWDCPDKYCRHYNGSV 222

Query: 172 SDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIFD 231
                VD  +  + D  L        L L++   DH GH+ GP+ P +      +D++  
Sbjct: 223 PFEERVDA-ILGYFD--LPSDEMPQFLTLYFEDPDHQGHQVGPDDPAITEAVVRIDEMIG 279

Query: 232 KLYNSCDDDTVL-----ILLGDHGMNEVGN 256
           +L    ++  V      IL+GDHGM    +
Sbjct: 280 RLIAGLEERGVFEDVNVILVGDHGMVGTCD 309
>ref|NP_005012.1| (NM_005021) ectonucleotide pyrophosphatase/phosphodiesterase 3;
           phosphodiesterase I/nucleotide pyrophosphatase 3;
           phosphodiesterase-I beta; gp130RB13-6; bovine intestinal
           phosphodiesterase [Homo sapiens]
 gb|AAC51813.1| (AF005632) phosphodiesterase I/nucleotide pyrophosphatase beta
           [Homo sapiens]
          Length = 875

 Score =  228 bits (577), Expect = 3e-58
 Identities = 44/232 (18%), Positives = 76/232 (31%), Gaps = 35/232 (15%)

Query: 46  APFQKAIIMVVDAFRSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTT 105
            P    I+  +D FR+++ ++  +  P ++K + + G       +  PT T P    + T
Sbjct: 159 PP---VILFSMDGFRAEYLYTWDTLMPNINK-LKTCGIHSKYMRAMYPTKTFPNHYTIVT 214

Query: 106 GSTPNFLDAV--------LNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFP 157
           G  P     +        LN   S +S    N   W  Q           G       +P
Sbjct: 215 GLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQ--PMWLTAMYQGLKAATYFWP 272

Query: 158 GMFDDCEGTAS----------FFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLDH 207
           G      G+             F    + +   +       L +        +++   D 
Sbjct: 273 GSEVAINGSFPSIYMPYNGSVPFEERISTLLKWL------DLPKAERPRFYTMYFEEPDS 326

Query: 208 IGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDTV-----LILLGDHGMNEV 254
            GH  GP S  +    + +D  F  L        +     +ILL DHGM++ 
Sbjct: 327 SGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQT 378
>dbj|BAA06333.1| (D30649) phosphodiesterase I [Rattus norvegicus]
          Length = 876

 Score =  226 bits (572), Expect = 1e-57
 Identities = 45/233 (19%), Positives = 79/233 (33%), Gaps = 35/233 (15%)

Query: 45  EAPFQKAIIMVVDAFRSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLT 104
           + P    I+  +D FR+++  +  +  P ++K + + G       +  PT T P    + 
Sbjct: 159 QPP---VILFSMDGFRAEYLQTWSTLLPNINK-LKTCGLHSKYMRAVYPTKTFPNHYTIV 214

Query: 105 TGSTPNFLDAV--------LNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLF 156
           TG  P     +        LN   S +S   +N   W  Q           G       +
Sbjct: 215 TGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWSGQ--PIWLTAMYQGLKAASYYW 272

Query: 157 PGMFDDCEGTAS----------FFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLD 206
           PG      G+             + S    +   +       L +        ++    D
Sbjct: 273 PGSDVAVNGSFPNIYRNYSNSVPYESRIATLLQWL------DLPKAERPSFYTIYVEEPD 326

Query: 207 HIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDTV-----LILLGDHGMNEV 254
             GHK+GP S  +    + +DD F  L        +     +I+L DHGM++ 
Sbjct: 327 SAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHNCVNIIVLADHGMDQT 379
>ref|NP_062243.1| (NM_019370) alkaline phosphodiesterase [Rattus norvegicus]
 gb|AAB61535.1| (U78787) alkaline phosphodiesterase [Rattus norvegicus]
          Length = 875

 Score =  226 bits (572), Expect = 1e-57
 Identities = 45/233 (19%), Positives = 79/233 (33%), Gaps = 35/233 (15%)

Query: 45  EAPFQKAIIMVVDAFRSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLT 104
           + P    I+  +D FR+++  +  +  P ++K + + G       +  PT T P    + 
Sbjct: 159 QPP---VILFSMDGFRAEYLQTWSTLLPNINK-LKTCGLHSKYMRAVYPTKTFPNHYTIV 214

Query: 105 TGSTPNFLDAV--------LNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLF 156
           TG  P     +        LN   S +S   +N   W  Q           G       +
Sbjct: 215 TGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWSGQ--PIWLTAMYQGLKAASYYW 272

Query: 157 PGMFDDCEGTAS----------FFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLD 206
           PG      G+             + S    +   +       L +        ++    D
Sbjct: 273 PGSDVAVNGSFPNIYRNYSNSVPYESRIATLLQWL------DLPKAERPSFYTIYVEEPD 326

Query: 207 HIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDTV-----LILLGDHGMNEV 254
             GHK+GP S  +    + +DD F  L        +     +I+L DHGM++ 
Sbjct: 327 SAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHNCVNIIVLADHGMDQT 379
>gb|AAB61536.1| (U78788) alkaline phosphodiesterase [Rattus norvegicus]
          Length = 875

 Score =  225 bits (570), Expect = 2e-57
 Identities = 45/233 (19%), Positives = 79/233 (33%), Gaps = 35/233 (15%)

Query: 45  EAPFQKAIIMVVDAFRSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLT 104
           + P    I+  +D FR+++  +  +  P ++K + + G       +  PT T P    + 
Sbjct: 159 QPP---VILFSMDGFRAEYLQTWSTLLPNINK-LKTCGLHSKYMRAMYPTKTFPNHYTIV 214

Query: 105 TGSTPNFLDAV--------LNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLF 156
           TG  P     +        LN   S +S   +N   W  Q           G       +
Sbjct: 215 TGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWSGQ--PIWLTAMYQGLKAASYYW 272

Query: 157 PGMFDDCEGTAS----------FFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLD 206
           PG      G+             + S    +   +       L +        ++    D
Sbjct: 273 PGSDVAVNGSFPNIYRNYSNSVPYESRIATLLQWL------DLPKAERPSFYTIYVEEPD 326

Query: 207 HIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDTV-----LILLGDHGMNEV 254
             GHK+GP S  +    + +DD F  L        +     +I+L DHGM++ 
Sbjct: 327 SAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHNCVNIIVLADHGMDQT 379
>pir||T40657 probable phophodiesterase-nucleotide pyrophosp hatase precursor -
           fission yeast (Schizosaccharomyces pombe)
 emb|CAA22177.1| (AL034352) putative nucleotide pyrophosphatase precursor
           [Schizosaccharomyces pombe]
          Length = 485

 Score =  224 bits (567), Expect = 4e-57
 Identities = 53/272 (19%), Positives = 95/272 (34%), Gaps = 26/272 (9%)

Query: 5   RWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQK-AIIMVVDAFRSDF 63
                  I +L +  + +    F    ++ P    S  +    FQ   I++ +D FR+D+
Sbjct: 30  SGLAIAAICILGILILAIVKL-FCFKAIIFPIVGGSFNNGTNVFQSTVIVISLDGFRADY 88

Query: 64  AFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAESD- 122
               +   P L   +            + P++T P    + TG  P     V N      
Sbjct: 89  L--YRGFTPNLLS-LAERNVHVPFLIPSFPSITFPNHYTIVTGLYPESHGIVSNNFFDPV 145

Query: 123 ------NSSTLANQD-SWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGT-ASFFVSDY 174
                 NS    N+D +W  +              + + ++PG  ++ E        SD 
Sbjct: 146 TGKQFVNSMPECNKDPTWWDKGEPIWVNAERNNVRSAVHMWPG--NEVENHGYRPTYSDG 203

Query: 175 TEVDNNVTRHID-----TQLDQKTEWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDI 229
              D  +    D       L  K    +L+ +   +D +GH  GP+SP +    +E+D +
Sbjct: 204 FNFDTTLREKKDRILEWLDLPDKDRPQLLLAYAPHVDMVGHAFGPDSPELNIIIQEVDIV 263

Query: 230 FDKLYNSCDDDTV-----LILLGDHGMNEVGN 256
             +L        +     +I L DHGM    +
Sbjct: 264 IGELIEGLKKRNIDKHVNIIFLSDHGMAPTSD 295
>ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo sapiens]
 gb|AAH13987.1|AAH13987 (BC013987) Similar to hypothetical protein MGC3079 [Homo sapiens]
          Length = 454

 Score =  222 bits (561), Expect = 2e-56
 Identities = 74/237 (31%), Positives = 107/237 (44%), Gaps = 43/237 (18%)

Query: 194 EWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDTVLILLGDHGMNE 253
           EWDVLI H+LG+DH GHK GP  P M  K  +MD +   L    ++DT+L++ GDHGM  
Sbjct: 5   EWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTT 64

Query: 254 VGNHGGSSAGETSAAMVFASPKFETAQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTA 313
            G+HGG S  E SAA+   SP   TA    T    P            + Q  LVPTL  
Sbjct: 65  NGDHGGDSELEVSAALFLYSP---TAVFPSTPPEEP----------EVIPQVSLVPTLAL 111

Query: 314 LLGLNTPKNNLGVLVSQMLGLWSPED-------QLNVLKNNADQMVQILQGQA--SRESD 364
           LLGL  P  N+G +++++               Q + L  NA Q+ + L   +  +++  
Sbjct: 112 LLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQ 171

Query: 365 AKEVYELYDTLNSNPSVK--------------------DYYNFLYEAQSYLTHASSN 401
           AKE+++L   L S  S                      +   FL  A++    + + 
Sbjct: 172 AKELHQL-QNLFSKASADYQWLLQSPKGAEATLPTVIAELQQFLRGARAMCIESWAR 227
 Score =  191 bits (481), Expect = 5e-47
 Identities = 38/258 (14%), Positives = 73/258 (27%), Gaps = 46/258 (17%)

Query: 626 AGTDKVNLIRDLHAFLTLFLITQS----RIQNIPLFMVYYFLEIFLRKATNRSFIFSSRD 681
           A      +I +L  FL            R     L +               +       
Sbjct: 199 AEATLPTVIAELQQFLRGARAMCIESWARFSLSFLLLHLLAAG------IPVTTPGPFTV 252

Query: 682 IYQTEALFQKLVLVLSVSTLLLEQVSFFSMGNSNSMASIDLSNAYNGVTLYQIE---FVG 738
            +Q  +           +  L+   +F+S G+     +I    A+ G             
Sbjct: 253 PWQAVS-----------AWALMATQTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPA 301

Query: 739 VLTFVSNWIGPLYWSTAGLSFLLEDH--VRNAIFAKIAEKNNDVKL-----------TTK 785
           +L   + +   L ++      LL         +  +     N+                 
Sbjct: 302 LLVGANTFASHLLFAVGCPLLLLWPFLCESQGLRKRQQPPGNEADARVRPEEEEEPLMEM 361

Query: 786 LVQQALTLRVYV-------VLAFSSVAISAVMITCFFLREHLFIWTVFSPKLLYQFVWTV 838
            ++ A               L    + I A  +    LR HL +W VF+PK +++ V  +
Sbjct: 362 RLRDAPQHFYAALLQLGLKYLFILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFI 421

Query: 839 LQFALVDVILSSIFVVLV 856
           +    V ++L    V+ V
Sbjct: 422 VSS--VGLLLGIALVMRV 437
>pir||A57080 cell surface antigen RB13-6 - rat
 emb|CAA88029.1| (Z47987) RB13-6 antigen [Rattus norvegicus]
          Length = 875

 Score =  220 bits (557), Expect = 7e-56
 Identities = 44/233 (18%), Positives = 78/233 (32%), Gaps = 35/233 (15%)

Query: 45  EAPFQKAIIMVVDAFRSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLT 104
           + P    I+  +D FR+++  +  +  P ++K + + G       +  PT T P    + 
Sbjct: 159 QPP---VILFSMDGFRAEYLQTWSTLLPNINK-LKTCGLHSKYMRAMYPTKTFPNHYTIV 214

Query: 105 TGSTPNFLDAV--------LNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLF 156
           TG  P     +        LN   S +S   +N   W  Q           G       +
Sbjct: 215 TGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWSGQ--PIWLTAMYQGLKAASYYW 272

Query: 157 PGMFDDCEGTAS----------FFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLD 206
            G      G+             + S    +   +       L +        ++    D
Sbjct: 273 LGSDVAVNGSFPNIYRNYSNSVPYESRIATLLQWL------DLPKAERPSFYTIYVEEPD 326

Query: 207 HIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDTV-----LILLGDHGMNEV 254
             GHK+GP S  +    + +DD F  L        +     +I+L DHGM++ 
Sbjct: 327 SAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHNCVNIIVLADHGMDQT 379
>dbj|BAA02053.1| (D12485) The first in-frame ATG codon is located at nucleotides
           17-19, followed by a second ATG codon 52 codons
           downstream. And the second ATG codon is potential
           initiation point for translation of NPPase. [Homo
           sapiens]
          Length = 930

 Score =  219 bits (554), Expect = 1e-55
 Identities = 41/230 (17%), Positives = 72/230 (30%), Gaps = 35/230 (15%)

Query: 45  EAPFQKAIIMVVDAFRSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLT 104
             P    ++  +D FR+++  +     P +  ++   G          PT T P    + 
Sbjct: 214 TPP---TLLFSLDGFRAEYLHTWGGLLPVI-SKLKKCGTYTKNMRPVYPTKTFPNHYSIV 269

Query: 105 TGSTPNFLDAV--------LNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLF 156
           TG  P     +        +N + S  S    N + +  +           G  +    +
Sbjct: 270 TGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGE--PIWVTAKYQGLKSGTFFW 327

Query: 157 PGMFDDCEGTAS----------FFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLD 206
           PG   +  G              F      V   +      QL +        L+    D
Sbjct: 328 PGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWL------QLPKDERPHFYTLYLEEPD 381

Query: 207 HIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDTV-----LILLGDHGM 251
             GH  GP S  +    + +D +   L +   +  +     LIL+ DHGM
Sbjct: 382 SSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGM 431
>pir||A39216 plasma cell membrane glycoprotein PC-1 - human
 gb|AAF36094.1| (AF110304) PDNP1 [Homo sapiens]
 emb|CAC39442.1| (AJ242020) plasma cell membrane glycoprotein [Homo sapiens]
          Length = 925

 Score =  219 bits (553), Expect = 2e-55
 Identities = 41/230 (17%), Positives = 72/230 (30%), Gaps = 35/230 (15%)

Query: 45  EAPFQKAIIMVVDAFRSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLT 104
             P    ++  +D FR+++  +     P +  ++   G          PT T P    + 
Sbjct: 209 TPP---TLLFSLDGFRAEYLHTWGGLLPVI-SKLKKCGTYTKNMRPVYPTKTFPNHYSIV 264

Query: 105 TGSTPNFLDAV--------LNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLF 156
           TG  P     +        +N + S  S    N + +  +           G  +    +
Sbjct: 265 TGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGE--PIWVTAKYQGLKSGTFFW 322

Query: 157 PGMFDDCEGTAS----------FFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLD 206
           PG   +  G              F      V   +      QL +        L+    D
Sbjct: 323 PGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWL------QLPKDERPHFYTLYLEEPD 376

Query: 207 HIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDTV-----LILLGDHGM 251
             GH  GP S  +    + +D +   L +   +  +     LIL+ DHGM
Sbjct: 377 SSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGM 426
>ref|NP_006199.1| (NM_006208) ectonucleotide pyrophosphatase/phosphodiesterase 1;
           phosphodiesterase I/nucleotide pyrophosphatase 1
           (homologous to mouse Ly-41 antigen); plasma-cell
           membrane glycoprotein [Homo sapiens]
 sp|P22413|PC1_HUMAN ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (PLASMA-CELL
           MEMBRANE GLYCOPROTEIN PC-1) [INCLUDES: ALKALINE
           PHOSPHODIESTERASE I ; NUCLEOTIDE PYROPHOSPHATASE
           (NPPASE)]
 gb|AAA63237.1| (M57736) plasma cell membrane glycoprotein PC-1 [Homo sapiens]
 dbj|BAA02054.1| (D12485) NPPase [Homo sapiens]
          Length = 873

 Score =  217 bits (548), Expect = 8e-55
 Identities = 41/230 (17%), Positives = 72/230 (30%), Gaps = 35/230 (15%)

Query: 45  EAPFQKAIIMVVDAFRSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLT 104
             P    ++  +D FR+++  +     P +  ++   G          PT T P    + 
Sbjct: 157 TPP---TLLFSLDGFRAEYLHTWGGLLPVI-SKLKKCGTYTKNMRPVYPTKTFPNHYSIV 212

Query: 105 TGSTPNFLDAV--------LNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLF 156
           TG  P     +        +N + S  S    N + +  +           G  +    +
Sbjct: 213 TGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGE--PIWVTAKYQGLKSGTFFW 270

Query: 157 PGMFDDCEGTAS----------FFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLD 206
           PG   +  G              F      V   +      QL +        L+    D
Sbjct: 271 PGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWL------QLPKDERPHFYTLYLEEPD 324

Query: 207 HIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDTV-----LILLGDHGM 251
             GH  GP S  +    + +D +   L +   +  +     LIL+ DHGM
Sbjct: 325 SSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGM 374
>emb|CAB99365.1| (AL117378) dJ131F15.2 (phosphodiesterase I/nucleotide
           pyrophosphatase 1 (homologous to mouse Ly-41 antigen)
           (PC1, NPPS)) [Homo sapiens]
          Length = 845

 Score =  216 bits (545), Expect = 2e-54
 Identities = 41/230 (17%), Positives = 72/230 (30%), Gaps = 35/230 (15%)

Query: 45  EAPFQKAIIMVVDAFRSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLT 104
             P    ++  +D FR+++  +     P +  ++   G          PT T P    + 
Sbjct: 129 TPP---TLLFSLDGFRAEYLHTWGGLLPVI-SKLKKCGTYTKNMRPVYPTKTFPNHYSIV 184

Query: 105 TGSTPNFLDAV--------LNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLF 156
           TG  P     +        +N + S  S    N + +  +           G  +    +
Sbjct: 185 TGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGE--PIWVTAKYQGLKSGTFFW 242

Query: 157 PGMFDDCEGTAS----------FFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLD 206
           PG   +  G              F      V   +      QL +        L+    D
Sbjct: 243 PGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWL------QLPKDERPHFYTLYLEEPD 296

Query: 207 HIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDTV-----LILLGDHGM 251
             GH  GP S  +    + +D +   L +   +  +     LIL+ DHGM
Sbjct: 297 SSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGM 346
>ref|NP_116023.1| (NM_032634) hypothetical protein MGC3079 [Homo sapiens]
 gb|AAH01030.1|AAH01030 (BC001030) Similar to phosphatidylinositol glycan, class O [Homo
           sapiens]
          Length = 454

 Score =  213 bits (539), Expect = 9e-54
 Identities = 71/237 (29%), Positives = 104/237 (42%), Gaps = 43/237 (18%)

Query: 194 EWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDTVLILLGDHGMNE 253
           EW+V   H LG+DH GHK GP  P M  K  +MD +   L    ++DT+L++ GDHGM  
Sbjct: 5   EWEVSNQHVLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTT 64

Query: 254 VGNHGGSSAGETSAAMVFASPKFETAQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTA 313
            G+HGG S  E SAA+   SP   TA    T    P            + Q  LVPTL  
Sbjct: 65  NGDHGGDSELEVSAALFLYSP---TAVFPSTPPEEP----------EVIPQVSLVPTLAL 111

Query: 314 LLGLNTPKNNLGVLVSQMLGLWSPED-------QLNVLKNNADQMVQILQGQA--SRESD 364
           LLGL  P  N+G +++++               Q + L  NA Q+ + L   +  +++  
Sbjct: 112 LLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQ 171

Query: 365 AKEVYELYDTLNSNPSVK--------------------DYYNFLYEAQSYLTHASSN 401
           AKE+++L   L S  S                      +   FL  A++    + + 
Sbjct: 172 AKELHQL-QNLFSKASADYQWLLQSPKGAEATLPTVIAELQQFLRGARAMCIESWAR 227
 Score =  192 bits (485), Expect = 2e-47
 Identities = 38/258 (14%), Positives = 73/258 (27%), Gaps = 46/258 (17%)

Query: 626 AGTDKVNLIRDLHAFLTLFLITQS----RIQNIPLFMVYYFLEIFLRKATNRSFIFSSRD 681
           A      +I +L  FL            R     L +               +       
Sbjct: 199 AEATLPTVIAELQQFLRGARAMCIESWARFSLSFLLLHLLAAG------IPVTTPGPFTV 252

Query: 682 IYQTEALFQKLVLVLSVSTLLLEQVSFFSMGNSNSMASIDLSNAYNGVTLYQIE---FVG 738
            +Q  +           +  L+   +F+S G+     +I    A+ G             
Sbjct: 253 PWQAVS-----------AWALMATQTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPA 301

Query: 739 VLTFVSNWIGPLYWSTAGLSFLLEDH--VRNAIFAKIAEKNNDVKL-----------TTK 785
           +L   + +   L ++      LL         +  +     N+                 
Sbjct: 302 LLVGANTFASHLLFAVGCPLLLLWPFLCESQGLRKRQQPPGNEADARVRPEEEEEPLMEM 361

Query: 786 LVQQALTLRVYV-------VLAFSSVAISAVMITCFFLREHLFIWTVFSPKLLYQFVWTV 838
            ++ A               L    + I A  +    LR HL +W VF+PK +++ V  +
Sbjct: 362 RLRDAPQHFYAALLQLGLKYLFILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFI 421

Query: 839 LQFALVDVILSSIFVVLV 856
           +    V ++L    V+ V
Sbjct: 422 VSS--VGLLLGIALVMRV 437
>ref|NP_299876.1| (NC_002488) phosphodiesterase-nucleotide pyrophosphatase precursor
           [Xylella fastidiosa 9a5c]
 pir||B82537 phosphodiesterase-nucleotide pyrophosphatase precursor XF2599
           [imported] - Xylella fastidiosa (strain 9a5c)
 gb|AAF85396.1|AE004067_3 (AE004067) phosphodiesterase-nucleotide pyrophosphatase precursor
           [Xylella fastidiosa 9a5c]
          Length = 433

 Score =  209 bits (529), Expect = 1e-52
 Identities = 61/267 (22%), Positives = 107/267 (39%), Gaps = 37/267 (13%)

Query: 14  VLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFRSDFAFSDQSNCPQ 73
           +      LL A   +P+R+ +     +   T  P  K +++++D  R+D    +    PQ
Sbjct: 7   LSIFIGTLLLAACSIPTRLNI----PTIAITAHPKYKLLLILIDGLRADAL--EHGQAPQ 60

Query: 74  LHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLN--------IAESDNSS 125
           L  R+ S G        + P +TLP    L TG  P+    V N          ES+N  
Sbjct: 61  L-ARLASDGVHALWMTPSYPALTLPNAYTLITGLRPDHHGIVHNTMEDPLLGAFESENQE 119

Query: 126 TLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASFFVSDYTEVDNNVTRHI 185
            +++   W  +           G  +   L+PG      GT     S +   + +++   
Sbjct: 120 AISDGRWWGGE--PIWVSAEHAGIHSATFLWPGSEASIAGTRP---SRWYAYNKHIS--A 172

Query: 186 DTQLDQKTEW---------DVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIFDKLYNS 236
           DTQ+ Q   W          ++IL +  ++  G+  GP+SP   A    +D    +L +S
Sbjct: 173 DTQITQALRWLNERGPDAPRLVILRFEQVNTAGNSFGPDSPQYAAAVHMIDSAIGRLIDS 232

Query: 237 CDD-----DTVLILLGDHGMNEV-GNH 257
                   DT +I++ D G+  + G+H
Sbjct: 233 LRQHGKLTDTDVIVVSDQGIAPIPGDH 259
>ref|NP_067547.1| (NM_021572) ectonucleotide pyrophosphatase/phosphodiesterase 5
           (putative function) [Homo sapiens]
 emb|CAB56566.1| (AL035701) dJ8B1.3 (similar to PLASMA-CELL MEMBRANE GLYCOPROTEIN
           PC-1) [Homo sapiens]
          Length = 477

 Score =  197 bits (498), Expect = 6e-49
 Identities = 50/250 (20%), Positives = 91/250 (36%), Gaps = 30/250 (12%)

Query: 24  ARGFLPSRVLLPGYTESRV-STEAPFQKAIIMVVDAFRSDFAFSDQSNCPQLHKRINSGG 82
              FL    +L   + S   S +   QK +++  D FR D+    +   P  H  +  G 
Sbjct: 2   TSKFLLVSFILAALSLSTTFSLQPDQQKVLLVSFDGFRWDYL--YKVPTPHFHYIMKYGV 59

Query: 83  AIPFTAHSTPPTVTLPRIKGLTTGSTP--------NFLDAVLNIAESDNSSTLANQDSWL 134
            +    +    T T P    L TG           +  D + N + S +   + +   W 
Sbjct: 60  HVKQVTNVFI-TKTYPNHYTLVTGLFAENHGIVANDMFDPIRNKSFSLDHMNIYDSKFW- 117

Query: 135 AQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASFFVSDYTEVDNNVTRHIDTQLDQKTE 194
            +A+         G  +   ++PG   D +    F    Y   + +V+   + ++ +  E
Sbjct: 118 EEATPIWITNQRAGHTSGAAMWPG--TDVKIHKRFPTH-YMPYNESVS--FEDRVAKIIE 172

Query: 195 W-------DVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIFDKLYNSCDDDTVL---- 243
           W       ++ +L++   D +GH  GP+SP M     ++D     L        +     
Sbjct: 173 WFTSKEPINLGLLYWEDPDDMGHHLGPDSPLMGPVISDIDKKLGYLIQMLKKAKLWNTLN 232

Query: 244 -ILLGDHGMN 252
            I+  DHGM 
Sbjct: 233 LIITSDHGMT 242
CPU time:   236.53 user secs.	    3.42 sys. secs	  239.95 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.317    0.179    0.476 

Gapped
Lambda     K      H
   0.270   0.0628    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 592124063
Number of Sequences: 887402
Number of extensions: 33674598
Number of successful extensions: 132730
Number of sequences better than 10.0: 1910
Number of HSP's better than 10.0 without gapping: 169
Number of HSP's successfully gapped in prelim test: 1786
Number of HSP's that attempted gapping in prelim test: 129018
Number of HSP's gapped (non-prelim): 4168
length of query: 860
length of database: 277,845,442
effective HSP length: 58
effective length of query: 802
effective length of database: 226,376,126
effective search space: 181553653052
effective search space used: 181553653052
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.2 bits)
S2: 78 (34.4 bits)