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GPI Anchor Biosynthesis Report: AAF59237.1 (GPI7 family, Drosophila melanogaster)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 
         (880 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Results of PSI-Blast iteration 5

Distribution of 66 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)
Sequences producing significant alignments: (bits) Value
gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melano... 894 0.0
pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast (... 655 0.0
ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class ... 645 0.0
ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class ... 642 0.0
ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]... 623 e-177
pir||T40715 hypothetical protein SPBC839.08c - fission yeast (S... 588 e-166
ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; ... 587 e-166
dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N sh... 575 e-162
sp|Q09782|YA93_SCHPO HYPOTHETICAL 85.7 KD PROTEIN C13G6.03 IN CH... 570 e-161
gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinosito... 568 e-160
gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melano... 543 e-153
pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragme... 538 e-151
gb|AAL39196.1| (AY069051) GH05767p [Drosophila melanogaster] 464 e-129
ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class ... 457 e-127
gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caeno... 415 e-114
pir||T02245 hypothetical protein P1.11659_3 - human >gi|2984587|... 414 e-114
ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan... 408 e-112
dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [M... 396 e-109
gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melano... 358 3e-97
ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans] 347 4e-94
gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melan... 333 7e-90
ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thalia... 332 2e-89
ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involv... 331 3e-89
ref|NP_495820.1| (NM_063419) Yeast YJ10 like [Caenorhabditis ele... 321 3e-86
ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thalia... 321 4e-86
dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:13516... 313 1e-83
ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) ... 250 9e-65
dbj|BAB55130.1| (AK027465) unnamed protein product [Homo sapiens] 247 5e-64
ref|NP_060203.1| (NM_017733) hypothetical protein FLJ20265 [Homo... 247 5e-64
ref|NP_105837.1| (NC_002678) hypothetical protein [Mesorhizobium... 240 8e-62
ref|NP_251941.1| (NC_002516) hypothetical protein [Pseudomonas a... 216 2e-54
ref|NP_281901.1| (NC_002163) hypothetical protein Cj0729 [Campyl... 214 4e-54
pdb|1EJJ|A Chain A, Crystal Structural Analysis Of Phosphoglycer... 204 4e-51
pir||T46865 phosphoglycerate mutase (EC 5.4.2.1), 2, 3-diphospho... 203 1e-50
ref|NP_458223.1| (NC_003198) 2,3-bisphosphoglycerate-independent... 203 1e-50
ref|NP_462604.1| (NC_003197) phosphoglyceromutase [Salmonella ty... 202 2e-50
ref|NP_465979.1| (NC_003210) highly similar to phosphoglycerate ... 201 5e-50
ref|NP_471880.1| (NC_003212) highly similar to phosphoglycerate ... 200 8e-50
ref|NP_418069.1| (NC_000913) putative 2,3-bisphosphoglycerate-in... 198 3e-49
ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo ... 198 4e-49
ref|NP_290195.1| (NC_002655) putative 2,3-bisphosphoglycerate-in... 196 1e-48
ref|NP_244424.1| (NC_002570) 2,3-bisphosphoglycerate-independent... 195 3e-48
ref|NP_391271.1| (NC_000964) phosphoglycerate mutase [Bacillus s... 194 4e-48
ref|NP_403728.1| (NC_003143) 2,3-bisphosphoglycerate-independent... 193 1e-47
ref|NP_371299.1| (NC_002758) 2, 3-diphosphoglycerate-independent... 192 3e-47
ref|NP_116023.1| (NM_032634) hypothetical protein MGC3079 [Homo ... 189 2e-46
pir||I40024 phosphoglycerate mutase - Bacillus subtilis >gi|4602... 189 2e-46
ref|NP_229990.1| (NC_002505) phosphoglycerate mutase, 2,3-bispho... 186 2e-45
dbj|BAA87261.1| (AB027957) Hypothetical protein [Schizosaccharom... 181 5e-44
Alignments
>gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melanogaster]
          Length = 880

 Score =  894 bits (2287), Expect = 0.0
 Identities = 880/880 (100%), Positives = 880/880 (100%)

Query: 1   MEQHKSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPP 60
           MEQHKSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPP
Sbjct: 1   MEQHKSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPP 60

Query: 61  PAYDSFVLLLVDALRDDFPDATSMPVAYSRACEKLKLHVDIPTVTMPRLKSITTGTLSNF 120
           PAYDSFVLLLVDALRDDFPDATSMPVAYSRACEKLKLHVDIPTVTMPRLKSITTGTLSNF
Sbjct: 61  PAYDSFVLLLVDALRDDFPDATSMPVAYSRACEKLKLHVDIPTVTMPRLKSITTGTLSNF 120

Query: 121 IDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFY 180
           IDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFY
Sbjct: 121 IDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFY 180

Query: 181 EGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDH 240
           EGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDH
Sbjct: 181 EGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDH 240

Query: 241 KSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTL 300
           KSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTL
Sbjct: 241 KSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTL 300

Query: 301 SVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLLNKARVKFGHEIVHRSDYYT 360
           SVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLLNKARVKFGHEIVHRSDYYT
Sbjct: 301 SVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLLNKARVKFGHEIVHRSDYYT 360

Query: 361 WYQNATLLHKKLLRPLREGDGGGASQVYYQNAKLNYMRLQLDGLKVGQLWLSVIAAVVLN 420
           WYQNATLLHKKLLRPLREGDGGGASQVYYQNAKLNYMRLQLDGLKVGQLWLSVIAAVVLN
Sbjct: 361 WYQNATLLHKKLLRPLREGDGGGASQVYYQNAKLNYMRLQLDGLKVGQLWLSVIAAVVLN 420

Query: 421 YTSHALDIIMTSSTLYSILLLVPISIAVYLTIDVAQALLKIALPPLYTRRLKISIPLPLP 480
           YTSHALDIIMTSSTLYSILLLVPISIAVYLTIDVAQALLKIALPPLYTRRLKISIPLPLP
Sbjct: 421 YTSHALDIIMTSSTLYSILLLVPISIAVYLTIDVAQALLKIALPPLYTRRLKISIPLPLP 480

Query: 481 LLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRITKTNVELNGRHLYTI 540
           LLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRITKTNVELNGRHLYTI
Sbjct: 481 LLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRITKTNVELNGRHLYTI 540

Query: 541 ASTCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLLLWARLHRHSQLPQSLASGA 600
           ASTCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLLLWARLHRHSQLPQSLASGA
Sbjct: 541 ASTCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLLLWARLHRHSQLPQSLASGA 600

Query: 601 ALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFWCCLALVLMLGYRAALPQAHSFGK 660
           ALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFWCCLALVLMLGYRAALPQAHSFGK
Sbjct: 601 ALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFWCCLALVLMLGYRAALPQAHSFGK 660

Query: 661 VPPTGALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVYGTSARKFSV 720
           VPPTGALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVYGTSARKFSV
Sbjct: 661 VPPTGALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVYGTSARKFSV 720

Query: 721 RLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIFVTLNTYSAD 780
           RLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIFVTLNTYSAD
Sbjct: 721 RLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIFVTLNTYSAD 780

Query: 781 IHAFLYLVVHTLRSDLRSVGIMQLHPPYSIAADSLIAPLYAALIMLPAAFYLCLLVGFRY 840
           IHAFLYLVVHTLRSDLRSVGIMQLHPPYSIAADSLIAPLYAALIMLPAAFYLCLLVGFRY
Sbjct: 781 IHAFLYLVVHTLRSDLRSVGIMQLHPPYSIAADSLIAPLYAALIMLPAAFYLCLLVGFRY 840

Query: 841 HLFIYSVFSPKVLYDCYTVLVFYLVFLVTSLYFKLFKHDA 880
           HLFIYSVFSPKVLYDCYTVLVFYLVFLVTSLYFKLFKHDA
Sbjct: 841 HLFIYSVFSPKVLYDCYTVLVFYLVFLVTSLYFKLFKHDA 880
>pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast
           (Schizosaccharomyces pombe)
 dbj|BAA21454.1| (AB004539) ORF YLL031c [Schizosaccharomyces pombe]
 emb|CAA16901.1| (AL021766) hypothetical protein [Schizosaccharomyces pombe]
          Length = 918

 Score =  655 bits (1674), Expect = 0.0
 Identities = 190/929 (20%), Positives = 331/929 (35%), Gaps = 103/929 (11%)

Query: 9   VYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPA-YDSFV 67
           ++   +L +   G   F  GF      + +                      P  ++  V
Sbjct: 26  IFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKIFERAV 85

Query: 68  LLLVDALRDDFPDATSMPVAYSRACEKLKLH---------------VDIPTVTMPRLKSI 112
           ++++DALR DF    +    Y                          D PT T  RLK +
Sbjct: 86  IVIIDALRYDFLIPYNDS-NYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQRLKGL 144

Query: 113 TTGTLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQV-ENH 171
           TTG+L  FID+  N   T   +D+ L + K  ++ +   GD TW  LF       + +  
Sbjct: 145 TTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSLDKQIVLLGDDTWDVLFHDYLNETLSQPA 204

Query: 172 DSFYVNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMD 231
            SF V D +  D  V + +   ++ +++ +LI HYLG+DH+GH  G   P +  KL +MD
Sbjct: 205 FSFNVPDLHGVDNKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMD 264

Query: 232 EVVKKILDHKSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYY----NNCSKTPSA 287
             VK+++D       LL++ GDHGM + G HGG++  E    L++Y         K P  
Sbjct: 265 RCVKEMMDLLDDS-TLLIVMGDHGMDNKGNHGGDSFDEINSVLWMYSKKPTFGYLKQPGK 323

Query: 288 SKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLLNKARVK 347
               NQ+DL PTLS+LL   IP  ++G LIPE       E+   A   N   L       
Sbjct: 324 VLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEPFYYYGDEYLSKAQKINIGQL----NRF 379

Query: 348 FGHEIVHRSDYYTWYQNATLLHKK----LLRPLREGDGGGASQVYYQNAKLNYMRLQLDG 403
           F    +  SD+ +     + +HK     L +   + D    +  Y++     +    +  
Sbjct: 380 FSEYDLDASDFLS-----SSVHKNNNSYLDQYFLDFDYARDAFSYFKAIWAEFSLFPM-- 432

Query: 404 LKVGQLWLSVIAAVVLNYTS--HALDIIMTSSTLYSI---LLLVPISIAVYLTIDVAQ-A 457
             +    L +I    L       ++   M+++   S+   L +  I I     +     A
Sbjct: 433 --IIGFLLLIIGGFNLALLMQDKSVIFRMSANMAPSVMKCLPVCLILILANNELHSPFPA 490

Query: 458 LLKIALPPLYTR----------RLKISIPLPLPLLACYAIRTLTLGSSSFIEFEYNTWYY 507
              + LP  Y              K  + L    +    +   + GS+SF  +E    ++
Sbjct: 491 EFYVLLPSFYILLNSFNQKLMEYFKGFVKLDYFSIFITFLHVCSFGSNSFTVWEDRLCHF 550

Query: 508 LGNTLILLTAFRTL----RWRI---TKTNVELNGRHLYTIASTCLWQMRKVLVVLMLLTL 560
           L  T+ L+   +                   +  + + +  + C  +     V   + T 
Sbjct: 551 LIITIGLVMFCKCFSEMSPLFACSTYSALAFILLQVISSYVTNCREEQGAFCVSTYISTP 610

Query: 561 MRYIHRLQAIRSTVVIFSMLLLWARLHRHSQLPQSLASGAALFMVYCFRGLNGQVLFFDV 620
              +  L  I   ++  S ++L   L  H +    L+       +  F  L      F +
Sbjct: 611 DNSLRTL--IVLALMALSSIILPLILQLHLRRVLGLSLKLYHLSILYFFELIS--SIFWI 666

Query: 621 PSHMAAK-LMVPTLV---------IFWCCLALVLMLGYRAALPQAHSFGKVPPTGALLQL 670
             H+ A   ++              +  C+  VL+  +        +   V         
Sbjct: 667 AHHVFANDALLEKQYHHVLYSLANTYVICILGVLIWQFFLLSRSKFAKINVIERSYF--- 723

Query: 671 LQTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVYGTSARKFSVRLVHVYKIIM 730
           +   L S L   + LQR    L L                +  S       +      + 
Sbjct: 724 VFALLYSFL---SFLQRPLGHLSL-FSCFLQILLLIQLKQWQPSVGHNFFSVTLGLLGLS 779

Query: 731 TIFLARMFFFYQGNSNSLSTIDLTPGY-IGQTNYNPSIVAIFVTLNTYSADIHAFLYLVV 789
                   FF  GN  ++S++D    +   ++  N +I AIF+ L+T  A I   + + +
Sbjct: 780 H-------FFTTGNQAAISSLDWNFAFIHSKSAENQAISAIFMFLHTVGAPILTCISIPL 832

Query: 790 HTLRSDLRSVGIMQLHPPYSIAADSLIAPLYAALIMLPAAFYLCLLVGFRYHLFIYSVFS 849
            +     +    +      ++   S    LY  LI     F+      FR HL ++ VF+
Sbjct: 833 FSFEPLSKKNRFLI-----NLFRFSFSFILYNLLISTSTVFFAGF---FRRHLMVWKVFA 884

Query: 850 PKVLYDCYTVLVFYLVF---LVTSLYFKL 875
           P+ +     ++   L        S   K 
Sbjct: 885 PRFMLSGILLVTHQLFVLIQCFGSSVVKF 913
>ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class N; endoplasmic
           reticulum membrane protein [Homo sapiens]
 gb|AAD11432.1| (AF109219) Mcd4p homolog [Homo sapiens]
          Length = 931

 Score =  645 bits (1648), Expect = 0.0
 Identities = 158/935 (16%), Positives = 274/935 (28%), Gaps = 175/935 (18%)

Query: 8   LVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSFV 67
           L +T+G+L  F+  A +F I F   S  V               +  + TP PP     V
Sbjct: 3   LFFTLGLLIHFVFFASIFDIYF--TSPLVHG-------------MTPQFTPLPPPARRLV 47

Query: 68  LLLVDALRDDFPDATSMPVAY---------SRACEKLKLHVDIPTVTMPRLKSITTGTLS 118
           L + D LR D                             H  +PT + P   ++  G   
Sbjct: 48  LFVADGLRADALYELDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVALIAGFYE 107

Query: 119 NFIDIALNVGHTEQMQDSFLHRLK-----------------QQNRVVSFAGDHTWVKLFP 161
           +   +A          DS  +  K                      V         + F 
Sbjct: 108 DVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDF- 166

Query: 162 SEFTRQVENHDSFY-VNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNAS 220
                   +   F  V DF+   RN  ++L +++      +  LH LG+D  GH    +S
Sbjct: 167 GAQDATKLDTWVFDNVKDFFHHARN-NQSLFSKINEEKI-VFFLHLLGIDTNGHAHRPSS 224

Query: 221 PRVPLKLKEMDEVVKKILDHK-----SFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLY 275
                 +K++D+ VK+I+        +      + T DHGM D G HG   P+ETL PL 
Sbjct: 225 RDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLV 284

Query: 276 LYYNNCSKTPS-------------------ASKRYNQIDLAPTLSVLLSVEIPTLSIGCL 316
            +                                 NQ D+AP ++ L+ V  P  S+G L
Sbjct: 285 TWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGIL 344

Query: 317 IPEMLQSLSLEHQLYAYFYNAHHLLNKARVKF-GHEIVHRSDYYTWYQNATLLHKKLLRP 375
             + L +     +  + F NA  +L + +VK    + V     +T +        KLL  
Sbjct: 345 PVDYLNNT-DLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPF--------KLLSD 395

Query: 376 LREGDGGGASQVYYQNAKLN--------YMRLQLDGLKVGQLWLSVI-----AAVVLNYT 422
            ++ +    ++ Y ++ K +         + L L GL     +             + + 
Sbjct: 396 SKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWI 455

Query: 423 SHALDIIMTSSTLYSILLLV---------PISIAVYLTIDVAQALLKIALPPLYTRRLKI 473
           S+A  +I+ S +     +           P S  V + I VA  LL  A P  +T  +  
Sbjct: 456 SYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSF-VAIGILVAFFLLIQACP--WTYYVYG 512

Query: 474 SIPLPLP--------LLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRI 525
            +PLP+         ++    +  LT   S F+       Y L  TL +      +    
Sbjct: 513 LLPLPIWYAVLREFQVIQDLVVSVLTYPLSHFV------GYLLAFTLGIEVL---VLSFF 563

Query: 526 TKTNVELNGRHLYTIASTCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLLLWAR 585
            +  +                  R  +  L                  + +F  L+    
Sbjct: 564 YRYMLTAGLTAFAAWPFLTRLWTRAKMTSL----------SWTFFSLLLAVF-PLMPVVG 612

Query: 586 LHRHSQLPQSLASGAALFMVYCFRGLNGQVLFF---DVPSHMAAKLMVPTLVIFWCCLAL 642
                 L         L  +     L  +   F   ++  H+   L     +        
Sbjct: 613 RKPDISLVMGAGLLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQS 672

Query: 643 VLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHNIL---------- 692
            L+      L        +        L+   L+S +L    L  +   L          
Sbjct: 673 SLLRKQGLPLMNQ----IISWATLASSLVVPLLSSPVLFQ-RLFSILLSLMSTYLLLSTG 727

Query: 693 ---LLPVLLVALQQTYKLCDV----------YGTSARKFSVRLVHVYKIIMTI------- 732
              L P++L  L   +   +                         + +            
Sbjct: 728 YEALFPLVLSCLMFVWINIEQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRA 787

Query: 733 ----FLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIFVTLNTYSADIHA-FLYL 787
               F     FF  GN  S+++ DL   Y   T ++P ++   +        +     + 
Sbjct: 788 FFLVFFLVTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFE 847

Query: 788 VVHTLRSDLRSVGIMQLHPPYSIAADSLIAPLYAA 822
            V            + +     I A      +   
Sbjct: 848 AVQLTTQLSSKSLFLIVLVISDIMALHFFFLVKDY 882
>ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class N [Mus musculus]
 dbj|BAA82619.1| (AB030279) phosphatidylinositolglycan class N [Mus musculus]
          Length = 931

 Score =  642 bits (1641), Expect = 0.0
 Identities = 155/927 (16%), Positives = 287/927 (30%), Gaps = 161/927 (17%)

Query: 8   LVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSFV 67
           L + +G+L  F+    +F I F   S  V               +  + TP PP     V
Sbjct: 3   LFFALGLLIHFVFFVSIFDIYF--TSPLVHG-------------MTPQFTPLPPPAKRLV 47

Query: 68  LLLVDALRDDFPDATSMPVAY---------SRACEKLKLHVDIPTVTMPRLKSITTGTLS 118
           L + D LR D                             H  +PT + P   ++  G   
Sbjct: 48  LFVADGLRADTLYELDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYE 107

Query: 119 NFIDIALNVGHTEQMQDSFLHRLK-----------------QQNRVVSFAGDHTWVKLFP 161
           +   +A          DS  +  K                      V         + F 
Sbjct: 108 DVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDF- 166

Query: 162 SEFTRQVENHDSFY-VNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNAS 220
                   +   F  V DF++  RN  ++L T++      +  LH LG+D  GH    +S
Sbjct: 167 GAHDATKLDTWVFDKVKDFFDAARN-NQSLFTKVNEEK-VVFFLHLLGVDTNGHAHRPSS 224

Query: 221 PRVPLKLKEMDEVVKKILDHK-----SFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLY 275
                 +K++D+ VK+I+               + T DHGM D G HG   P+ETL P  
Sbjct: 225 REYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFV 284

Query: 276 LYYNNCSKTPS-------------------ASKRYNQIDLAPTLSVLLSVEIPTLSIGCL 316
            +        +                     +  NQ D+AP ++ L+ V  P  S+G L
Sbjct: 285 TWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGIL 344

Query: 317 IPEMLQSLSLEHQLYAYFYNAHHLLNKARVKF-GHEIVHRSDYYTWYQNATLLHKKLLRP 375
               L +  L  +  + F NA  +L + +VK    +       +T +        KLL  
Sbjct: 345 PVGYLNNTGL-FKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPF--------KLLSD 395

Query: 376 LREGDGGGASQVYYQNAKLN--------YMRLQLDGLKVGQLWLSVI-----AAVVLNYT 422
            ++ D    ++ Y +  K +         + L L GL     +  +      A   + + 
Sbjct: 396 SQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWM 455

Query: 423 SHALDIIMTSSTLYSILLLV-----PISIA---VYLTIDVAQALLKIALPPLYTRRLKIS 474
           S+   +I+ S +                +    +   + VA  L+  A P  +T  +   
Sbjct: 456 SYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACP--WTYYVYCL 513

Query: 475 IPLPLP--------LLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRIT 526
           +P+P+         ++       LT   S F+   Y   + LG  +++L+ F        
Sbjct: 514 LPVPIWYAVLREHEVIQDLVESLLTFPRSHFV--AYLLVFTLGIEVLVLSFFYRYMLTAG 571

Query: 527 KTNVEL--NGRHLYTIASTCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLLLWA 584
                       L+T A           +     +L+  +  L  +       S+++   
Sbjct: 572 LIVFAGWPFLTQLWTRAKITF-------LSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAG 624

Query: 585 RLHRHSQ-------LPQSLASGAALFMVYCFRGLNGQVLFFDVPSHMAA-----KLMVPT 632
            L              +++       +V   + L+  +  + V S   +      L +  
Sbjct: 625 FLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMN 684

Query: 633 LVIFWCCLALVLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHNIL 692
            ++ W  LA          +    S   +    A +  L + +++ LLL+   + +   L
Sbjct: 685 QIVSWATLASS-------LVAPLLSSTALSQRLASI--LLSLMSTYLLLSTGYEALFP-L 734

Query: 693 LLPVLLVALQQ------TYKLCDVYGTSARKFSVRLVHVYKIIM-----------TIFLA 735
           +L  L+    Q                           + +               +F  
Sbjct: 735 VLSCLMFVWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLVFFL 794

Query: 736 RMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIFVTLNTYSADIHA-FLYLVVHTLRS 794
              FF  GN  S+++ DL   Y   T ++P ++   +        +     +  V     
Sbjct: 795 LTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQITTQ 854

Query: 795 DLRSVGIMQLHPPYSIAADSLIAPLYA 821
                  + +     I A      +  
Sbjct: 855 LSSKGLFLVVLIISDIMALHFFFLVKD 881
>ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]
 gb|AAB93646.1| (AF003137) Hypothetical protein C27A12.9 [Caenorhabditis elegans]
          Length = 905

 Score =  623 bits (1592), Expect = e-177
 Identities = 188/956 (19%), Positives = 339/956 (34%), Gaps = 156/956 (16%)

Query: 6   SWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPP-PPAYD 64
             L+ +I +L A      +F  GF      +  K S               T      Y 
Sbjct: 6   RILLVSINILLALF----IFQNGFLLKRQEILSKSSCSDAHA-----QPGQTCWMKQQYQ 56

Query: 65  SFVLLLVDALRDDFPD------ATSMPVAYSR-------------ACEKLKLHVDIPTVT 105
             +L+LVDALR DF          S    Y R                   L  D PT T
Sbjct: 57  RVILILVDALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTT 116

Query: 106 MPRLKSITTGTLSNFIDIALNVGHTEQ-MQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEF 164
           + RLK++TTGTL  FID   N        +DSF+++  Q  + V+  GD TW+ LFP++F
Sbjct: 117 LQRLKALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFPNQF 176

Query: 165 TRQVENHDSFYVNDFYEGDRNVTKTLE------------------TELERSDWSLLILHY 206
           ++    +DSF +ND    D  + + +                    E+  S+ S++I H+
Sbjct: 177 SKTAA-YDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHF 235

Query: 207 LGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGGGHGGNT 266
           LG+DH GH  G + P +   L++MD ++ + ++             DHGM   G HGG +
Sbjct: 236 LGVDHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKSD--------DHGMTSTGDHGGES 287

Query: 267 PAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEML--QSL 324
             E      L ++   +     +  +QID+ PT+S+L+ + IP  ++G +I ++      
Sbjct: 288 ENEIRAG-ILVHSKKHQIILPERPIHQIDIVPTISLLMGLPIPFSNLGTVITQLFTRDLW 346

Query: 325 SLEHQLY---------------AYFYNAHHLLNKARVKFGHEIVHRSDYYTWYQNATLLH 369
            +  Q+                A   N   L         H I   +         + + 
Sbjct: 347 EIARQMMGFVWQDSVGIFAETYAAQKNFGEL-------HSHTIRDSNTMEEQLDTMSRIQ 399

Query: 370 KKLLRPLREGDGGG---ASQVYYQNAKLNYMRLQLD--------GLKVGQLWLSVIAAVV 418
             L     + D            +          +         G  + Q  L       
Sbjct: 400 TLLRVSWTQFDDAYINAGIFSLVEAIMFLITNEVMSLEWIIYRTGCGLLQAALLTDKTDS 459

Query: 419 LNYTSHALDIIMTSSTLYSILLLVPISIAVYLTIDVAQALLKIALPPLYTRRLKISIPLP 478
                  L + +  S L SI+ +   ++ + ++I  +    K+  P L            
Sbjct: 460 DGSARTLLLMTLAVSCLSSIISMCHKALQIRISIK-SMLSAKVIGPIL------------ 506

Query: 479 LPLLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRITKTNVELNGRHLY 538
                   I +++L S+S++ +E     Y   +L+ L     LR    +         L+
Sbjct: 507 ------VIIHSISLFSNSYVVYEAQVVRYFLQSLVTLVFLEKLRSTALRPRKPFKLNFLW 560

Query: 539 TIASTCLWQMRKVLVVLMLLTLMR---YIHRLQAIRSTVVIFSMLLLWARLHRHSQLPQS 595
              +    Q + +++  +++  +R     HR +        +        L R +Q+ + 
Sbjct: 561 KFVN----QDQNLIIFTLIMVGLRSEPIFHRCREEEVGCDTYYPSRQAGSLTRDAQVVRL 616

Query: 596 L----ASGAALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFWCCLALVLMLGYRAA 651
           L    +   A   V+ + GL       +  S  +++ +       W  +A++++    A+
Sbjct: 617 LFALGSLAVANLSVFKYYGLRDTKSQIESNSKRSSETIRILSATSWLHIAIIVLHSVFAS 676

Query: 652 LPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHN------ILLLPVLLVALQQTY 705
           L    S   +           +    SL+ A L  R  N       LL+PV  +      
Sbjct: 677 LTHDVSRANLSA--------HSLSVISLICAVLAWREGNSAICAHFLLMPVY-ILFGDGL 727

Query: 706 KLCDVYGTSARKFSVRLVHVYKIIMTI-FLARMFFFYQGNSNSLSTIDLTPGYIGQ---T 761
               +   +        V    I  TI  L  + F++ G+S  +S+I     ++G    T
Sbjct: 728 IPAIIIFIAVSVLIAEFVSREFIASTIALLIPLGFYHLGHSPVISSIPWNAAFVGIPGGT 787

Query: 762 NYNPSIVAIFVTLNTYSADIHAFLYLVVHTLRSDLRSVGIMQLHPPYSIAADSLIAPLYA 821
                     +    +SA       + V +  S+       ++  P +    +    L  
Sbjct: 788 ALRVLPALFVLFHLNFSA----ISSIFVISSESESSQ----KMSAPNTAWTLTETLVL-- 837

Query: 822 ALIMLPAAFYLCLLVGF-RYHLFIYSVFSPKVLYDCYTVLVFYLVFLVTSLYFKLF 876
              M   A   CL+    R HL ++ +F+PK +++C   +VF        +Y + F
Sbjct: 838 ---MTIRATLTCLVSSIHRRHLMVWKIFAPKFIFECILTIVFIFSANFFLIYRQFF 890
>pir||T40715 hypothetical protein SPBC839.08c - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA17011.1| (AL021816) hypothetical protein [Schizosaccharomyces pombe]
 emb|CAB46701.1| (AL096796) hypothetical protein [Schizosaccharomyces pombe]
          Length = 935

 Score =  588 bits (1500), Expect = e-166
 Identities = 131/880 (14%), Positives = 263/880 (29%), Gaps = 134/880 (15%)

Query: 9   VYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSFVL 68
           +  +G+L   +    +F I F   +  +   +                           L
Sbjct: 5   LLLLGILFHVVFLKSIFDIYFV--TPLIHGMKQYSAGEA--------------PAKRLFL 48

Query: 69  LLVDALRDDFPDATSMPV---------------AYSRACEKLKLHVDIPTVTMPRLKSIT 113
           ++ D LR D                                   H  +PT + P   ++ 
Sbjct: 49  IVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALI 108

Query: 114 TGTLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFP-----------S 162
            G   +   +           DS  ++     R     G    + +F             
Sbjct: 109 AGFYEDVSAVTKGWKKNPVNFDSVFNQS----RHTYSFGSEDILPMFSEGASDPSRVDTF 164

Query: 163 EFTRQVENHDS----FYVNDFYEGDRNVTKTLETELERS----DWSLLILHYLGLDHIGH 214
            ++ ++E+  S         F   D  + ++LE +        D  +  LH LG+D IGH
Sbjct: 165 MYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGH 224

Query: 215 VEGNASPRVPLKLKEMDEVVKKILDHK-----SFPNVLLMLTGDHGMADGGGHGGNTPAE 269
            +   S      ++ +D  +++++D       +      + T DHGM+D G HG      
Sbjct: 225 NKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDN 284

Query: 270 TLVPLYLYYNNC-----SKTPSASK-------------RYNQIDLAPTLSVLLSVEIPTL 311
           T  P+  +          K     +                Q D+A  +S L+ +  P  
Sbjct: 285 TRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVN 344

Query: 312 SIGCLIPEMLQSLSLEHQLYAYFYNAHHLLNKARVKFGHEIVHRSDY--YTWYQNATLLH 369
           S+G +  + L   S   +      NA  +  +  +K   +      +  Y+  +N T + 
Sbjct: 345 SVGQIPLDYLDC-SSRRKAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQ 403

Query: 370 KKLLRPLREGDGGGASQVYYQNAKLNYMRLQLDGLKVGQL--WLSVIAAVVLNYTSHA-- 425
                 +      G  ++  ++   ++ +  L GL+  Q   WL + + V   Y S    
Sbjct: 404 ASFYNSVIADIESGEYEIAIEHC-FHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGY 462

Query: 426 -LDIIMTSSTLYSILLLVPISIAVYLTIDVAQALLK-----IALPPLYTRRLKISIPLPL 479
            +  + + +   S  ++ P+S+   +  ++   L+       + PP Y        P   
Sbjct: 463 VICFVFSLNIEPSSKIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGY--ALFPTIF 520

Query: 480 PLLACYAIRTLTLGSSSFIEFEYN-----TWYYLGNTLILLTAFRTLRW-RITKTNVELN 533
             L         LG  +F+              L  +L +L   + + +    +    + 
Sbjct: 521 LQLIHSIFPNTKLGFKNFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVI 580

Query: 534 GR----HLYTIASTCLWQMRKVLVVLMLLTLMRYIH---------RLQAIRSTVVIFSML 580
                   + + +   +  + + V   +LT +              L  I +     S+ 
Sbjct: 581 LMGLAAWPWLLHADYAFSHKTISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVA 640

Query: 581 LLWARLHRHSQLPQSLASGAALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFWCCL 640
            ++  L+R +Q  Q  ++     +V     +   V      +    + +    ++     
Sbjct: 641 GVFYILYRRNQAFQYSSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAF 700

Query: 641 ALVLMLGYRAALPQAHSF-GKVPPTGALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLV 699
            L  +  Y    P  H    K      L  L  T   +  +L+   +      L  V+L 
Sbjct: 701 GL-FITSYII--PSHHIRSCKHYFLDRLAILFLTFSPTMCMLSISFE-----ALFYVVLF 752

Query: 700 ALQQTYKLCDVYG-------------TSARKFSVRLVHVYKIIMTIFLARMFFFYQGNSN 746
                +   +                    KF + L H+   +       + FF  GN  
Sbjct: 753 ITLGLWMELETELQKYTEQLHPEYSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVA 812

Query: 747 SLSTIDLTPGYIGQTNYNPSIVAIFVTLNTYSADIHAFLY 786
           SLST  L         +NP      +        I     
Sbjct: 813 SLSTFALDSVKRFIPVFNPVTQGALLMYTILVPFIALSAA 852
>ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; Mcd4p [Saccharomyces
           cerevisiae]
 sp|P36051|YKQ5_YEAST HYPOTHETICAL 105.7 KD PROTEIN IN TPK3-PIR1 INTERGENIC REGION
 pir||S37786 hypothetical protein YKL165c - yeast (Saccharomyces cerevisiae)
 emb|CAA81489.1| (Z26877) unknown [Saccharomyces cerevisiae]
 emb|CAA82007.1| (Z28165) ORF YKL165c [Saccharomyces cerevisiae]
 prf||2118404A ORF [Saccharomyces cerevisiae]
          Length = 919

 Score =  587 bits (1499), Expect = e-166
 Identities = 144/914 (15%), Positives = 269/914 (28%), Gaps = 140/914 (15%)

Query: 1   MEQHKSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPP 60
           M       +  +G+L        +F I F   S  V                    + P 
Sbjct: 1   MWNKTRTTLLAVGVLFHLFYLWSIFDIYFI--SPLVHGMS-------------PYQSTPT 45

Query: 61  PAYDSFVLLLVDALRDDFPDAT-SMPV-------------AYSRACEKLKLHVDIPTVTM 106
           P      L++ D LR D      + PV                        H  +PT + 
Sbjct: 46  PPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESR 105

Query: 107 PRLKSITTGTLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPS---- 162
           P   ++  G   +   +           DSF ++           G    + +F      
Sbjct: 106 PGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQST----HTYSFGSPDILPMFKDGASD 161

Query: 163 -------EFTRQVENHDSFYVNDFYEGDRNVTKTLE------------TELERSDWSLLI 203
                   +    E+     +    E D  V + L+                R D ++  
Sbjct: 162 PNKVDTWMYDHTFEDFTQSSI----ELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFF 217

Query: 204 LHYLGLDHIGHVEGNASPRVPLKLKEMDE----VVKKILDHKSFPNVLLMLTGDHGMADG 259
           LH LG D  GH     S      +K +D+    ++ K+    +      + T DHGM+  
Sbjct: 218 LHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAF 277

Query: 260 GGHGGNTPAETLVPLYLYYNNCSKTPS------------------ASKRYNQIDLAPTLS 301
           G HG   P  T  PL  +    +K                           Q D+A  +S
Sbjct: 278 GSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMS 337

Query: 302 VLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLLNKARVKFGHEIVHRSDYYTW 361
            L+ V  P  S+G L    +       +L A + NA  +L +  VK   E++    +Y  
Sbjct: 338 YLIGVNYPKNSVGELPIAYIDGKE-SDKLAALYNNARSILEQYLVK-QDEVIDSQFFYKE 395

Query: 362 YQNATLLHKKLL----RPLREGDGGGASQVYYQNAKL--NYMRLQLDGLKVGQL--WLSV 413
           Y                 L +    G + +  +   L    M++ L+GL       W  +
Sbjct: 396 YFKFVEKSHSHYLEEIETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTYNWRFI 455

Query: 414 IAAVVLNYTSHALDIIMTSSTLYSI------LLLVPISIAVYLTI-DVAQALLKIALPPL 466
              V   +        +     + +          P+S AV+ +I  +   +L     P 
Sbjct: 456 RTIVTFGFVGWIFFSFIIFLKSFILENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPF 515

Query: 467 YTRRLKISIPLPLPLLACYAIRTLTLGSSSFIEFEYNT--WYYLGNTLILLTAFRTLRW- 523
               + +  PL       Y     ++  S   EF   T  W  +  T+ +++ +  + + 
Sbjct: 516 -NFYMYLLFPLYFWS---YIFTNRSVLRSGIKEFFKGTSPWKRVLITISIISVYEGIVYG 571

Query: 524 RITKTNVELNGRHLYTIASTCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLLLW 583
              +    L    L      C  +   V ++ ++ +++          ST  +F  + + 
Sbjct: 572 FFHRWTFTLITNILAFYPFICGVRELSVNILWIITSVL---------LSTFTLFDAVKIE 622

Query: 584 ARLHRHSQLPQSLASGAALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFWCCLAL- 642
                H      + S          R  +     F +   + A  M+         L L 
Sbjct: 623 DLNQIHLAGLLIILSAFYALYKIHSRINSYTRAIFAIQISLVA-AMLAVTHRSVISLQLR 681

Query: 643 ------VLMLGYRAALPQAHSFGKV----PPTGALLQLLQTNLT---SSLLLAALLQRVH 689
                   + G+            +    P     ++LL   LT   S ++L    +   
Sbjct: 682 QGLPRESQVAGWIIFFVSLFVMPILHYRKPNNDYKVRLLIIYLTFAPSFIILTISFES-- 739

Query: 690 NILLLPVLLVALQQTYKLCDVYGTSARKFSVRLVHVYKIIMTI--FLARMFFFYQGNSNS 747
              L   L  +    +   +      +            +  I  FL ++ FF  GN  S
Sbjct: 740 ---LFYFLFTSYMVQWIEIENKIKEMKTQKDENWLQVLRVSVIGFFLLQVAFFGTGNVAS 796

Query: 748 LSTIDLTPGYIGQTNYNPSIVAIFVTLNTYSAD--IHAFLYLVVHTLRSDLRSVGIMQLH 805
           +S+  L         ++P ++   + L        +   L ++   L     ++  + + 
Sbjct: 797 ISSFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIIS 856

Query: 806 PPYSIAADSLIAPL 819
               I + +    L
Sbjct: 857 M-SDILSLNFFYLL 869
>dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N short form [Mus
           musculus]
          Length = 798

 Score =  575 bits (1468), Expect = e-162
 Identities = 141/824 (17%), Positives = 259/824 (31%), Gaps = 149/824 (18%)

Query: 8   LVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSFV 67
           L + +G+L  F+    +F I F   S  V               +  + TP PP     V
Sbjct: 3   LFFALGLLIHFVFFVSIFDIYF--TSPLVHG-------------MTPQFTPLPPPAKRLV 47

Query: 68  LLLVDALRDDFPDATSMPVAY---------SRACEKLKLHVDIPTVTMPRLKSITTGTLS 118
           L + D LR D                             H  +PT + P   ++  G   
Sbjct: 48  LFVADGLRADTLYELDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYE 107

Query: 119 NFIDIALNVGHTEQMQDSFLHRLK-----------------QQNRVVSFAGDHTWVKLFP 161
           +   +A          DS  +  K                      V         + F 
Sbjct: 108 DVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDF- 166

Query: 162 SEFTRQVENHDSFY-VNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNAS 220
                   +   F  V DF++  RN  ++L T++      +  LH LG+D  GH    +S
Sbjct: 167 GAHDATKLDTWVFDKVKDFFDAARN-NQSLFTKVNEEK-VVFFLHLLGVDTNGHAHRPSS 224

Query: 221 PRVPLKLKEMDEVVKKILDHK-----SFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLY 275
                 +K++D+ VK+I+               + T DHGM D G HG   P+ETL P  
Sbjct: 225 REYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFV 284

Query: 276 LYYNNCSKTPS-------------------ASKRYNQIDLAPTLSVLLSVEIPTLSIGCL 316
            +        +                     +  NQ D+AP ++ L+ V  P  S+G L
Sbjct: 285 TWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGIL 344

Query: 317 IPEMLQSLSLEHQLYAYFYNAHHLLNKARVKF-GHEIVHRSDYYTWYQNATLLHKKLLRP 375
               L +  L  +  + F NA  +L + +VK    +       +T +        KLL  
Sbjct: 345 PVGYLNNTGL-FKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPF--------KLLSD 395

Query: 376 LREGDGGGASQVYYQNAKLN--------YMRLQLDGLKVGQLWLSVI-----AAVVLNYT 422
            ++ D    ++ Y +  K +         + L L GL     +  +      A   + + 
Sbjct: 396 SQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWM 455

Query: 423 SHALDIIMTSSTLYSILLLV-----PISIA---VYLTIDVAQALLKIALPPLYTRRLKIS 474
           S+   +I+ S +                +    +   + VA  L+  A P  +T  +   
Sbjct: 456 SYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACP--WTYYVYCL 513

Query: 475 IPLPLP--------LLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRIT 526
           +P+P+         ++       LT   S F+   Y   + LG  +++L+ F        
Sbjct: 514 LPVPIWYAVLREHEVIQDLVESLLTFPRSHFV--AYLLVFTLGIEVLVLSFFYRYMLTAG 571

Query: 527 KTNVEL--NGRHLYTIASTCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLLLWA 584
                       L+T A           +     +L+  +  L  +       S+++   
Sbjct: 572 LIVFAGWPFLTQLWTRAKITF-------LSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAG 624

Query: 585 RLHRHSQ-------LPQSLASGAALFMVYCFRGLNGQVLFFDVPSHMAA-----KLMVPT 632
            L              +++       +V   + L+  +  + V S   +      L +  
Sbjct: 625 FLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMN 684

Query: 633 LVIFWCCLALVLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHNIL 692
            ++ W  LA          +    S   +    A +  L + +++ LLL+   + +   L
Sbjct: 685 QIVSWATLASS-------LVAPLLSSTALSQRLASI--LLSLMSTYLLLSTGYEALFP-L 734

Query: 693 LLPVLLVALQQ------TYKLCDVYGTSARKFSVRLVHVYKIIM 730
           +L  L+    Q                           + +   
Sbjct: 735 VLSCLMFVWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQ 778
>sp|Q09782|YA93_SCHPO HYPOTHETICAL 85.7 KD PROTEIN C13G6.03 IN CHROMOSOME I
 pir||S62432 major facilitator protein homolog - fission yeast
           (Schizosaccharomyces pombe)
 pir||T37638 major facilitator protein homolog - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA91096.1| (Z54308) putative major facilitator superfamily protein
           [Schizosaccharomyces pombe]
          Length = 758

 Score =  570 bits (1456), Expect = e-161
 Identities = 210/903 (23%), Positives = 360/903 (39%), Gaps = 184/903 (20%)

Query: 9   VYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSFVL 68
               G+    + G++LFL+GFFP       K  +                PP   D  V 
Sbjct: 3   FAFFGIFWLQIFGSILFLLGFFPHKNDSTGKAMS------------NQFSPPAVIDQVVF 50

Query: 69  LLVDALRDDFPDATSMPVAYSR-------ACEKLKLHVDIPTVTMPRLKSITTGTLSNFI 121
           ++VDALR DF  + S  + +++                  PTVTMPRLK++TTGT+  F+
Sbjct: 51  VMVDALRADFVFSKSHNMPFTQSLLYNSTHGIGFSAFARSPTVTMPRLKALTTGTIPGFL 110

Query: 122 DIALNVGHTEQM-----QDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYV 176
           D+ LN+  ++       QDS++++L   N+ + F GD TW+KLFPS F++  E   SF+V
Sbjct: 111 DVLLNIAESDTGSSIEAQDSWVYQLNSFNKKIEFYGDDTWLKLFPSAFSK-FEGTTSFFV 169

Query: 177 NDFYEGDRNVTKTLETELE---RSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEV 233
           +D+ E D NVT+  +  L       W  LILHYLG+DHIGH+ G +SP + +KL E+D +
Sbjct: 170 SDYTEVDNNVTRNFDHALPSSLSHSWDALILHYLGVDHIGHLYGPSSPLLNIKLLEIDTI 229

Query: 234 VKKILDHKSF------PNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNNCSK---- 283
           + +I  +          + L++L GDHGM + G HGG++  ET   L L + +       
Sbjct: 230 ISRIYKYLQEYDEKTNTHSLIVLCGDHGMNEVGNHGGSSSGETTAALSLLFPSNELSHIN 289

Query: 284 ---------TPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQL-YAY 333
                      S  +R  Q+D+ PT+ +LL + IP  ++G ++  + +          A 
Sbjct: 290 KPILNMDDNPYSILERVEQVDVVPTICLLLGIPIPKGNMGKVLSPVTELWKDTKTAKMAA 349

Query: 334 FYNAHHLLNKARVKFGHEIVHRSDYYTWYQNATLLHKKLLRPLREGDGGGASQVYYQNAK 393
             N   L                           L    L    +       ++  +N  
Sbjct: 350 LSNLFQL--------------------SLLKNPSLTTSELSTQFQDSDLNDIRLALEN-- 387

Query: 394 LNYMRLQLDGLKVGQLWLSVIAAVVLNYTSHALDIIMTSSTLYSILLLVPISIAVYLTID 453
                              + + +V   +S++LD            +LV ISI    +I 
Sbjct: 388 -------------------LQSQMVAQSSSYSLD-----------RMLVAISILGACSI- 416

Query: 454 VAQALLKIALPPLYTRRLKISIPLPLPLLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLI 513
               L  I    LY    ++    P  +     +      SSSFIE E+  WY+   +L 
Sbjct: 417 ----LSLILFRNLYN-YKELLAFAPFVVQNIIIV-----FSSSFIEEEHVIWYFAAVSLS 466

Query: 514 LLTAFRTLRWRITKTNVELNGRHLYTIASTCLWQMRKVLVVLMLLTLMRYIHRLQAIRST 573
           LL           KT +  + + L+ ++    W         +   +  +I     +++ 
Sbjct: 467 LLQLLNP------KTRLAGSLQ-LFCLSIIKRWNQTGQKYSDLRDIVDDFIAPSTFMKTI 519

Query: 574 VVIFSMLLLWARLHRHSQLPQSLASGAALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTL 633
           + + S  +      R       L+S     M   F  L        + S    +L +   
Sbjct: 520 LCVTSAFMPAI---RSPSPINFLSS-----MFIAFYKLMP------IISKHLNELPIIAS 565

Query: 634 VIFWCCLALVLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHNILL 693
             +   + ++    +   L    S             L+  L+  +LL   L+ +   LL
Sbjct: 566 FDYTFFVRII----WSLLLISFLSKPTFK-------QLRCQLSLFILLLTRLENMGLYLL 614

Query: 694 LPVLLVALQQTYKLCDVYGTSARKFSVRLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDL 753
                          D++  +  +           +M     ++ FF  GNSNSL+T+DL
Sbjct: 615 Y--------------DIWQRTMPEEG-----TLASVMYYVAEQVAFFSLGNSNSLATVDL 655

Query: 754 TPGYIGQTNYNPSIVAIFVTLNTYSADIHAFLYLVVHTLRSDLRSVGIMQLHPPYSIAAD 813
           +  Y G  +YN   V I +  + ++  +   L+     +   +++  IM        ++ 
Sbjct: 656 SQAYTGLDSYNIFAVGILLFTSVFAGALWWCLHQPKRMMDRSVKTFWIM--------SSI 707

Query: 814 SLIAPLYAALIMLPAAFYLCLLVGFRYHLFIYSVFSPKVLYDCYTVLVFYLV-FLVTSLY 872
           SL     +  IM             R+HLF++SVFSPK+LY+     +++L   L++++ 
Sbjct: 708 SLTFLCISCFIM-------------RHHLFVWSVFSPKLLYNASWASMYFLAKCLISTIM 754

Query: 873 FKL 875
            +L
Sbjct: 755 VRL 757
>gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinositol glycan, class N [Mus
           musculus]
          Length = 826

 Score =  568 bits (1451), Expect = e-160
 Identities = 142/824 (17%), Positives = 260/824 (31%), Gaps = 149/824 (18%)

Query: 8   LVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSFV 67
           L + +G+L  F+  A +F I F   S  V               +  + TP PP     V
Sbjct: 3   LFFALGLLIHFVFFASIFDIYF--TSPLVHG-------------MTPQFTPLPPPAKRLV 47

Query: 68  LLLVDALRDDFPDATSMPVAY---------SRACEKLKLHVDIPTVTMPRLKSITTGTLS 118
           L + D LR D                             H  +PT + P   ++  G   
Sbjct: 48  LFVADGLRADTLYELDEDGNSRAPFIRNVIIHEGSWGVSHTRVPTESRPGHVALIAGFYE 107

Query: 119 NFIDIALNVGHTEQMQDSFLHRLK-----------------QQNRVVSFAGDHTWVKLFP 161
           +   +A          DS  +  K                      V         + F 
Sbjct: 108 DVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDF- 166

Query: 162 SEFTRQVENHDSFY-VNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNAS 220
                   +   F  V DF++  RN  ++L T++      +  LH LG+D  GH    +S
Sbjct: 167 GAHDATKLDTWVFDKVKDFFDAARN-NQSLFTKVNEEK-VVFFLHLLGIDTNGHAHRPSS 224

Query: 221 PRVPLKLKEMDEVVKKILDHK-----SFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLY 275
                 +K++D+ VK+I+               + T DHGM D G HG   P+ETL P  
Sbjct: 225 REYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFV 284

Query: 276 LYYNNCSKTPS-------------------ASKRYNQIDLAPTLSVLLSVEIPTLSIGCL 316
            +        +                     +  NQ D+AP ++ L+ V  P  S+G L
Sbjct: 285 TWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGIL 344

Query: 317 IPEMLQSLSLEHQLYAYFYNAHHLLNKARVKF-GHEIVHRSDYYTWYQNATLLHKKLLRP 375
               L +  L  +  + F NA  +L + +VK    +       +T +        KLL  
Sbjct: 345 PVGYLNNTGL-FKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPF--------KLLSD 395

Query: 376 LREGDGGGASQVYYQNAKLN--------YMRLQLDGLKVGQLWLSVI-----AAVVLNYT 422
            ++ D    ++ Y +  K +         + L L GL     +  +      A   + + 
Sbjct: 396 SQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWM 455

Query: 423 SHALDIIMTSSTLYSILLLV-----PISIA---VYLTIDVAQALLKIALPPLYTRRLKIS 474
           S+   +I+ S +                +    +   + VA  L+  A P  +T  +   
Sbjct: 456 SYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACP--WTYYVYCL 513

Query: 475 IPLPLP--------LLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRIT 526
           +P+P+         ++       LT   S F+   Y   + LG  +++L+ F        
Sbjct: 514 LPVPIWYAVLREHEVIQDLVESLLTFPRSHFV--AYLLVFTLGIEVLVLSFFYRYMLTAG 571

Query: 527 KTNVEL--NGRHLYTIASTCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLLLWA 584
                       L+T A           +     +L+  +  L  +       S+++   
Sbjct: 572 LIVFAGWPFLTQLWTRAKITF-------LSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAG 624

Query: 585 RLHRHSQ-------LPQSLASGAALFMVYCFRGLNGQVLFFDVPSHMAA-----KLMVPT 632
            L              +++       +V   + L+  +  + V S   +      L +  
Sbjct: 625 FLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMN 684

Query: 633 LVIFWCCLALVLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHNIL 692
            ++ W  LA          +    S   +    A +  L + +++ LLL+   + +   L
Sbjct: 685 QIVSWATLASS-------LVAPLLSSTALSQRLASI--LLSLMSTYLLLSTGYEALFP-L 734

Query: 693 LLPVLLVALQQ------TYKLCDVYGTSARKFSVRLVHVYKIIM 730
           +L  L+    Q                           + +   
Sbjct: 735 VLSCLMFVWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQ 778
>gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melanogaster]
          Length = 874

 Score =  543 bits (1385), Expect = e-153
 Identities = 139/888 (15%), Positives = 263/888 (28%), Gaps = 119/888 (13%)

Query: 7   WLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSF 66
           W+ Y + +    L    +F+I F   S  +          +   L         P  +  
Sbjct: 2   WIAYALVV--HVLLLGSIFVIYF--RSPVITG-----LTPQKHLLYYG----LEPPANRL 48

Query: 67  VLLLVDALRDDFPDATSMPV------AYSRACEKLKLHVDIPTVTMPRLKSITTGTLSNF 120
           VL++ D  R D     +          + R          +PT T P   ++  G   + 
Sbjct: 49  VLIVTDGFRADSFFEENCRYVPNLRKIFLREGVVGVSRTRVPTETRPGHITLIAGLYEDP 108

Query: 121 IDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSE---------FTRQVENH 171
             +           D+  +R  Q        G +  + +F            F     + 
Sbjct: 109 SAVLRGWKSNPIDFDTVFNRSSQ----TYAWGANDVLNVFSHVSNGGEINLRFYNHDLDF 164

Query: 172 DSFYVNDFYEGDRNVTKTL-------ETELERSDWSLLILHYLGLDHIGHVEGNASPRVP 224
              Y  D YE D  V K +          L+R+   +  LH LGLD  GHV    +P+  
Sbjct: 165 SPGY--DAYEEDEWVFKRVKLLLQQKREALQRAQNVVFFLHLLGLDTAGHVHKPGAPKFR 222

Query: 225 LKLKEMDEVVKKILDHKS----FPNVLLMLTGDHGMADGGGH------GGNTPAETLVPL 274
             L++ ++ V  I               +LT DHGM D G        GG T        
Sbjct: 223 RTLEKTEKGVYAIYQEFERVFPDKRTAYLLTADHGMTDSGASRAVPKPGGRT-------- 274

Query: 275 YLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYF 334
             +  N            Q  L P +S LL +  P  + G L    L ++S E++  A  
Sbjct: 275 --FMPNNEGPAMPLHELEQAQLTPLMSALLGLAPPMNNFGKLPLGYL-NVSKEYEAMAAH 331

Query: 335 YNAHHLLNKA-RVKFGHEIVHRSDYYTWYQN-ATLLHKKLLRPLREGDGGGASQVYYQNA 392
            NA  LL +   ++  H+    +D    Y        K+    + +        +    +
Sbjct: 332 VNALQLLEQYVALQKQHKKGFFADILLEYDVLNAEAIKRYKDTIVQLQKKREYSLCIDKS 391

Query: 393 KLNYMRLQLDGLKVGQLW-----LSVIAAVVLNYTSHALDIIMTSSTLYSILLLVPISIA 447
           ++  M   L+G+     +     L    +  L +  +   ++  +      L+L   +  
Sbjct: 392 QV-IMSQALEGIDYYHGYYRRVLLLSTTSTFLGWMFYIYRLLSRNRASKVELVLERSNKI 450

Query: 448 VYLTI--DVAQALLKIAL---PPLYTRRLKISIPLPLPLLACYAIRTLTLGSSSFIEFEY 502
           V ++I   V   ++ +     P   +  L +   + L  L  + I   +  +S++     
Sbjct: 451 VRVSIVSSVIVLIICLLSQGTPLDISFYLLLPYFVWLKALQPWNINFSSSPASAYSVPAL 510

Query: 503 NTWYYLGNTLILLTAFRTLRWRITKTNVELNGRHLYTIASTCLWQMRKVLVVLMLLTLMR 562
            T  +    L+LL A   L          +        A    W+  +           R
Sbjct: 511 QTSMW---QLVLLIACAELMVFTFFERRLIALCFCV-FACYNSWENFQWK--------SR 558

Query: 563 YIHRLQAIRSTVVIFSMLLLWARLHRHSQLPQSLASGAALFMVYCFRGLNGQVLFFDVPS 622
                 A+   +  F +L L                GA + +++     N +        
Sbjct: 559 DFFSWLALVLILSCFPLLPLSVGYQ------NGYLLGAGVIVIFTNSFWNSKSRLCYRNH 612

Query: 623 HMAAKLMVPTLVIFWCCLALVLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLA 682
              +  ++         +    +      +P       +     L  L+    +  L   
Sbjct: 613 TKYSNALILLQ-----TILCAYLHSNGINIP-----IPLKLASWL-YLVYAFASILLSKE 661

Query: 683 ALLQR----VHNIL--LLPVLL-----VALQQTYKLCDVYGTSARKFSVRLVHVYKIIMT 731
           + L      +   L  L   L      V +Q      ++   +    + R V       T
Sbjct: 662 SRLDLRLAQIGFNLGSLYATLCTSYEAVFVQLLTIELNISLRAQSARAERSVLRLAF--T 719

Query: 732 IFLARMF-FFYQGNSNSLSTIDLTPGYIGQTNYNPS-IVAIFVTLNTYSADIHAFLYLVV 789
           + L   F  F  GN  S+S+ D        +++ P  I+ + +        +   +    
Sbjct: 720 LLLYTFFSLFGSGNIASISSFDPNIARCYLSHFAPFVIMGLVLLKLLVPVVLIMSVIYAN 779

Query: 790 HTLRSDLRSVGIMQLHPPYSIAADSLIAPLYAALIMLPAAFYLCLLVG 837
                       + L     +   + +  +      L     +   V 
Sbjct: 780 SEFVRQHEEQIFICLLLICDVMGLNFLFLVRNQGSWLDIGTSISHFVI 827
>pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragment)
 emb|CAB70839.1| (AL137607) hypothetical protein [Homo sapiens]
          Length = 825

 Score =  538 bits (1373), Expect = e-151
 Identities = 132/816 (16%), Positives = 236/816 (28%), Gaps = 151/816 (18%)

Query: 118 SNFIDIALNVGHTEQMQDSFLHRLK-----------------QQNRVVSFAGDHTWVKLF 160
            +   +A          DS  +  K                      V         + F
Sbjct: 1   EDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDF 60

Query: 161 PSEFTRQVENHDSFY-VNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNA 219
                    +   F  V DF+   RN  ++L +++      +  LH LG+D  GH    +
Sbjct: 61  -GAQDATKLDTWVFDNVKDFFHHARN-NQSLFSKINEEKI-VFFLHLLGIDTNGHAHRPS 117

Query: 220 SPRVPLKLKEMDEVVKKILDHK-----SFPNVLLMLTGDHGMADGGGHGGNTPAETLVPL 274
           S      +K++D+ VK+I+        +      + T DHGM D G HG   P+ETL PL
Sbjct: 118 SRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPL 177

Query: 275 YLYYNNCSKTPS-------------------ASKRYNQIDLAPTLSVLLSVEIPTLSIGC 315
             +                                 NQ D+AP ++ L+ V  P  S+G 
Sbjct: 178 VTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGI 237

Query: 316 LIPEMLQSLSLEHQLYAYFYNAHHLLNKARVKF-GHEIVHRSDYYTWYQNATLLHKKLLR 374
           L  + L +     +  + F NA  +L + +VK    + V     +T +        KLL 
Sbjct: 238 LPVDYLNNT-DLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPF--------KLLS 288

Query: 375 PLREGDGGGASQVYYQNAKLN--------YMRLQLDGLKVGQLWLSVI-----AAVVLNY 421
             ++ +    ++ Y ++ K +         + L L GL     +             + +
Sbjct: 289 DSKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGW 348

Query: 422 TSHALDIIMTSSTLYSILLLV---------PISIAVYLTIDVAQALLKIALPPLYTRRLK 472
            S+A  +I+ S +     +           P S  V + I VA  LL  A P  +T  + 
Sbjct: 349 ISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSF-VAIGILVAFFLLIQACP--WTYYVY 405

Query: 473 ISIPLPLP--------LLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWR 524
             +PLP+         ++    +  LT   S F+       Y L  TL +      +   
Sbjct: 406 GLLPLPIWYAVLREFQVIQDLVVSVLTYPLSHFV------GYLLAFTLGIEVL---VLSF 456

Query: 525 ITKTNVELNGRHLYTIASTCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLLLWA 584
             +  +                  R  +  L                  + +F  L+   
Sbjct: 457 FYRYMLTAGLTAFAAWPFLTRLWTRAKMTSL----------SWTFFSLLLAVF-PLMPVV 505

Query: 585 RLHRHSQLPQSLASGAALFMVYCFRGLNGQVLFF---DVPSHMAAKLMVPTLVIFWCCLA 641
                  L         L  +     L  +   F   ++  H+   L     +       
Sbjct: 506 GRKPDISLVMGAGLLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQ 565

Query: 642 LVLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHNIL--------- 692
             L+      L        +        L+   L+S +L    L  +   L         
Sbjct: 566 SSLLRKQGLPLMNQ----IISWATLASSLVVPLLSSPVLFQ-RLFSILLSLMSTYLLLST 620

Query: 693 ----LLPVLLVALQQTYKLCDV----------YGTSARKFSVRLVHVYKIIMTI------ 732
               L P++L  L   +   +                         + +           
Sbjct: 621 GYEALFPLVLSCLMFVWINIEQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRR 680

Query: 733 -----FLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIFVTLNTYSADIHA-FLY 786
                F     FF  GN  S+++ DL   Y   T ++P ++   +        +     +
Sbjct: 681 AFFLVFFLVTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAF 740

Query: 787 LVVHTLRSDLRSVGIMQLHPPYSIAADSLIAPLYAA 822
             V            + +     I A      +   
Sbjct: 741 EAVQLTTQLSSKSLFLIVLVISDIMALHFFFLVKDY 776
>gb|AAL39196.1| (AY069051) GH05767p [Drosophila melanogaster]
          Length = 608

 Score =  464 bits (1183), Expect = e-129
 Identities = 482/483 (99%), Positives = 483/483 (99%)

Query: 398 RLQLDGLKVGQLWLSVIAAVVLNYTSHALDIIMTSSTLYSILLLVPISIAVYLTIDVAQA 457
           +LQLDGLKVGQLWLSVIAAVVLNYTSHALDIIMTSSTLYSILLLVPISIAVYLTIDVAQA
Sbjct: 126 QLQLDGLKVGQLWLSVIAAVVLNYTSHALDIIMTSSTLYSILLLVPISIAVYLTIDVAQA 185

Query: 458 LLKIALPPLYTRRLKISIPLPLPLLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTA 517
           LLKIALPPLYTRRLKISIPLPLPLLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTA
Sbjct: 186 LLKIALPPLYTRRLKISIPLPLPLLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTA 245

Query: 518 FRTLRWRITKTNVELNGRHLYTIASTCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIF 577
           FRTLRWRITKTNVELNGRHLYTIASTCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIF
Sbjct: 246 FRTLRWRITKTNVELNGRHLYTIASTCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIF 305

Query: 578 SMLLLWARLHRHSQLPQSLASGAALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFW 637
           SMLLLWARLHRHSQLPQSLASGAALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFW
Sbjct: 306 SMLLLWARLHRHSQLPQSLASGAALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFW 365

Query: 638 CCLALVLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHNILLLPVL 697
           CCLALVLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHNILLLPVL
Sbjct: 366 CCLALVLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHNILLLPVL 425

Query: 698 LVALQQTYKLCDVYGTSARKFSVRLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGY 757
           LVALQQTYKLCDVYGTSARKFSVRLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGY
Sbjct: 426 LVALQQTYKLCDVYGTSARKFSVRLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGY 485

Query: 758 IGQTNYNPSIVAIFVTLNTYSADIHAFLYLVVHTLRSDLRSVGIMQLHPPYSIAADSLIA 817
           IGQTNYNPSIVAIFVTLNTYSADIHAFLYLVVHTLRSDLRSVGIMQLHPPYSIAADSLIA
Sbjct: 486 IGQTNYNPSIVAIFVTLNTYSADIHAFLYLVVHTLRSDLRSVGIMQLHPPYSIAADSLIA 545

Query: 818 PLYAALIMLPAAFYLCLLVGFRYHLFIYSVFSPKVLYDCYTVLVFYLVFLVTSLYFKLFK 877
           PLYAALIMLPAAFYLCLLVGFRYHLFIYSVFSPKVLYDCYTVLVFYLVFLVTSLYFKLFK
Sbjct: 546 PLYAALIMLPAAFYLCLLVGFRYHLFIYSVFSPKVLYDCYTVLVFYLVFLVTSLYFKLFK 605

Query: 878 HDA 880
           HDA
Sbjct: 606 HDA 608
>ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class O [Mus musculus]
 dbj|BAA96254.1| (AB038560) Pig-o [Mus musculus]
          Length = 1101

 Score =  457 bits (1164), Expect = e-127
 Identities = 140/589 (23%), Positives = 219/589 (36%), Gaps = 86/589 (14%)

Query: 3   QHKSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPP--- 59
           +  S L++   +   F  G  LF  GF      +  + S      P  L       P   
Sbjct: 10  RKVSVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNQSSCQELPGPGPLPWGSHGKPGAC 69

Query: 60  --PPAYDSFVLLLVDALRDDFPDATSMPVA----------------------YSRACEKL 95
             P  +   VL+L+DALR DF       V                               
Sbjct: 70  WMPSRFSRVVLVLIDALRFDFAQPQRSHVPGEPPVSVPFLGKLGSLQRILESQPHHGRLY 129

Query: 96  KLHVDIPTVTMPRLKSITTGTLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHT 155
           +  VD PT TM RLK++TTG+L  FID   N      ++D+ + +L    R V F GD T
Sbjct: 130 RSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNVIQQLNSAGRRVVFMGDDT 189

Query: 156 WVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHV 215
           W  LFP     Q     SF V D +  D  + + L   L+   W +LI H+LG+DH GH 
Sbjct: 190 WRDLFPG-AFSQAFFFSSFNVRDLHTVDNGILEHLYPTLDGGSWDVLIAHFLGVDHCGHK 248

Query: 216 EGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLY 275
            G   P +  KL +MD+V++ +++     + LL++ GDHGM   G HGG++  E    L+
Sbjct: 249 HGPHHPEMAKKLSQMDQVIQGLIERLE-NDTLLVVAGDHGMTMNGDHGGDSELEVSAALF 307

Query: 276 LYYNNC---SKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEH---- 328
           LY       S  P   +   Q+ L PTL++LL + IP  + G ++ E+    S       
Sbjct: 308 LYSPTALFPSVPPEEPEVIPQVSLVPTLALLLGLPIPFGNTGEVMAELFSGGSDSSHPHS 367

Query: 329 ----QLYAYFYNAHHL------------------LNKARVKFGHEIVHRSDYYTWYQNAT 366
               Q+ A   NA  +                  L++ +  F         +    Q A 
Sbjct: 368 SALAQVSALHINAQQVSRFLHTYSAATQDLQVKELHRLQTLFSKASARYQHFLRDPQEAE 427

Query: 367 LLHKKLLRPLREGDGGGASQ-VYYQN-AKLNY--------------------MRLQLDGL 404
                L    ++      ++ +  ++ A+ +                      +L +   
Sbjct: 428 AALSTLTAEFQQF--LRGARALCIESWARFSLVRMAGGAALLAAACLLCLLASQLAVAPG 485

Query: 405 KVGQLWLSVIAAVVLNYTSHALDIIMTSSTLYSILLLVPISIAVYLTIDVAQALLKIALP 464
            + +  L +  A  L   +  +     S T  S + LV +         +          
Sbjct: 486 FLFRPLLLIPVAWGL---TWTILYAGVSVTTGSKIDLVVLGAVAAAGSLLPFLWKAWVSR 542

Query: 465 PLYTRRLKISIPLPLPLLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLI 513
               R L   +P+P P+L    IR  T  S SF   E     +L  +L+
Sbjct: 543 G-SKRPLAPLLPVPRPVLILLLIRLATFFSDSFFVVEARATPFLLGSLV 590
 Score =  156 bits (393), Expect = 1e-36
 Identities = 40/251 (15%), Positives = 80/251 (30%), Gaps = 47/251 (18%)

Query: 666  ALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVYGTSAR-------KF 718
              L  + +      ++ ALL     ++LL V  V+L         +              
Sbjct: 835  YQLGSVYSAA----MVTALLLLAFPLMLLHVERVSLVFLLLFLQSFLLLHLLAAGTPVAT 890

Query: 719  SVRLVHVYKIIM-TIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIV---AIFVTL 774
                  +++ +   + LA   F+  G+    S I     ++G  + + S     A+ V  
Sbjct: 891  PGPFTVLWQAVSAWVLLATQTFYSTGHQPVFSAIHWHAAFVGFPDGHGSSTWLPALLVGA 950

Query: 775  NTYSADIHAFLYLVVHTLRSDL--RSVGIMQLHPPY------------------------ 808
            NT+++ +   +   +  L   L  R     +   P                         
Sbjct: 951  NTFASHLLFAVGCPLLLLWPFLCERQGPKRRQPLPGSESEARVRPEEEEELQEPLMEVRL 1010

Query: 809  ----SIAADSLIAPLYAALIMLPAAFYLCLL--VGFRYHLFIYSVFSPKVLYDCYTVLVF 862
                +    +L+      L +L A    C L     R HL ++ VF+PK +++    +V 
Sbjct: 1011 RDAPNHFNAALLQLGLKYLFILGAQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVS 1070

Query: 863  YLVFLVTSLYF 873
             +  L+     
Sbjct: 1071 SVGLLLGIALV 1081
 Score = 79.3 bits (194), Expect = 3e-13
 Identities = 26/169 (15%), Positives = 51/169 (29%), Gaps = 36/169 (21%)

Query: 654 QAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVYGT 713
            A                        ++ ALL     ++LL V  V+L         +  
Sbjct: 842 SAA-----------------------MVTALLLLAFPLMLLHVERVSLVFLLLFLQSFLL 878

Query: 714 SAR-------KFSVRLVHVYKIIM-TIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNP 765
                             +++ +   + LA   F+  G+    S I     ++G  + + 
Sbjct: 879 LHLLAAGTPVATPGPFTVLWQAVSAWVLLATQTFYSTGHQPVFSAIHWHAAFVGFPDGHG 938

Query: 766 SIV---AIFVTLNTYSADIHAFLYLVVHTLRSDL--RSVGIMQLHPPYS 809
           S     A+ V  NT+++ +   +   +  L   L  R     +   P S
Sbjct: 939 SSTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCERQGPKRRQPLPGS 987
>gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caenorhabditis elegans]
          Length = 929

 Score =  415 bits (1058), Expect = e-114
 Identities = 136/852 (15%), Positives = 258/852 (29%), Gaps = 130/852 (15%)

Query: 6   SWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDS 65
           SW      +    +    +F + +            T P         +           
Sbjct: 2   SWKFLIASITVHLVLIYSIFDVYY------------TSPLVHGIPPQFINSQE--APAKR 47

Query: 66  FVLLLVDALRDDFPDATSMPVAYSRA------CEKLKLHVDIPTVTMPRLKSITTGTLSN 119
             ++  D LR D  +       Y  +               IPT + P   +I  G   +
Sbjct: 48  IFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITED 107

Query: 120 FIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLF-------PSEFTRQVENHD 172
              +A          DS  +R           G    V LF          ++   E+  
Sbjct: 108 ISAVAKGWKKNPVQFDSVFNRSSYS----WMWGSPDIVNLFDDLPNAESFSYSADEEDFA 163

Query: 173 SFYVNDFYEGDRNVTKTLETELE------------RSDWSLLILHYLGLDHIGHVEGNAS 220
           S   ++    D+ V +  E  LE            R   S+  LH LG+D  GH     S
Sbjct: 164 SKDASNL---DKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMS 220

Query: 221 PRVPLKLKEMDEVVKKILDHKS----FPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYL 276
            +    +K +D  ++K+               + T DHGM D G HG  +  E L P   
Sbjct: 221 RQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVA 280

Query: 277 YYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYN 336
           +     +        NQIDLAP +S L+   IP  S+G L  +M+ S    ++  A   N
Sbjct: 281 WGAGVKQG-GPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEAN 339

Query: 337 AHHLLNKARVKFGHEIVHRSDYYTWYQNA-----TLLHKKLLRPLREGDGGGASQVYYQN 391
              L  +  + F      R  ++  ++         L   L +  R+     A+ ++  N
Sbjct: 340 FKQLKEQ--IIFLKNAKSRRLWFRQFEKFGDKAMESLRTTLAQLGRDRRFSVATSLFADN 397

Query: 392 AKL--------NYMRLQLDGLKV---GQLWLSVIAAVVLNYTSHALDIIMTSSTLYSILL 440
           A L        +    Q+ G  V      W++++ + + N TS     ++    L+ I L
Sbjct: 398 AHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIALVVSFLHNSTSKENLSLLVPHHLFIIPL 457

Query: 441 LVPISIAVYLTIDVAQ----------ALLKIALPPLYTR---RLKISIPLPLPLLACYAI 487
              +    Y ++ + Q            +      L  R    +K     P  L    ++
Sbjct: 458 ACSLLFTAYCSLSMTQTIYIILPIYLISILENHSKLTQRIREHVKALSAQPDWLNKVLSV 517

Query: 488 RTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRITKTNVELNGR---HLYTIASTC 544
                    F++       ++G ++ +     T   R     V +        Y+     
Sbjct: 518 EV-------FVKPFLG---FVGFSITICIFVLTFMDRAFLAAVFVLLMALPQFYSHPIVS 567

Query: 545 LWQMRKVLVVLMLLTLMRYIHRLQAIRST-----VVIFSMLLLWARLHRHSQL------- 592
            W         + L L+  I              + I S ++     HR S+        
Sbjct: 568 YWSKT-----WLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFLCHRLSRRSCLTRIQ 622

Query: 593 --------PQSLA---SGAALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFWCCLA 641
                    QS          +     + L          +  +++ + P  +  W    
Sbjct: 623 RMLELMIYVQSATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSLQPPSIARWISWT 682

Query: 642 LVLMLGYRAALPQAHSFGKVPPTG--ALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLV 699
            + +       P   +   +        L         S+   +L   +  +LL   +  
Sbjct: 683 SIPL---SVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFLVLLTLFVRF 739

Query: 700 ALQQT--YKLCDVYGTSARKFSVRLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGY 757
                   +L  +   S +  +   V + + ++ +       F  GN  S+++ + +   
Sbjct: 740 EFGHLSDVELLQLKVDSTKISTGEYVELRRTVVCVSFVLCPLFGTGNFASINSFNPSTLN 799

Query: 758 IGQTNYNPSIVA 769
           +  + ++P  +A
Sbjct: 800 LFISVFSPFTMA 811
>pir||T02245 hypothetical protein P1.11659_3 - human
 gb|AAC07985.1| (AC004472) P1.11659_3 [Homo sapiens]
          Length = 880

 Score =  414 bits (1055), Expect = e-114
 Identities = 113/438 (25%), Positives = 181/438 (40%), Gaps = 42/438 (9%)

Query: 3   QHKSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPP--- 59
           Q  S L++   +   F  G  LF  GF      +    S      P +L       P   
Sbjct: 2   QKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGAC 61

Query: 60  --PPAYDSFVLLLVDALRDDFPDATSMP---VAYSRACEKLKLHVDIPTVTMPRLKSITT 114
                +   VL+L+DALR DF                    +  VD PT TM RLK++TT
Sbjct: 62  WMASRFSRVVLVLIDALRFDFAQPQHSHRILEIQPHHARLYRSQVDPPTTTMQRLKALTT 121

Query: 115 GTLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSF 174
           G+L  FID   N      ++D+ + +L    R V F GD TW  LFP  F++      SF
Sbjct: 122 GSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDDTWKDLFPGAFSKAFF-FPSF 180

Query: 175 YVNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVV 234
            V D    D  + + L   ++  +W +LI H+LG+DH GH  G   P +  KL +MD+V+
Sbjct: 181 NVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVI 240

Query: 235 KKILDHKSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNNC---SKTPSASKRY 291
           + +++     + LL++ GDHGM   G HGG++  E    L+LY       S  P   +  
Sbjct: 241 QGLVERLE-NDTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPEEPEVI 299

Query: 292 NQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEH-------QLYAYFYNAHHL---- 340
            Q+ L PTL++LL + IP  +IG ++ E+               Q  A   NA  +    
Sbjct: 300 PQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFL 359

Query: 341 --------------LNKARVKFGHEIVHRSDYYTWYQNATLLHKKLLRPLREGDGGGASQ 386
                         L++ +  F              + A      ++  L++      ++
Sbjct: 360 HTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEATLPTVIAELQQF--LRGAR 417

Query: 387 -VYYQNAKLNYMRLQLDG 403
            +  ++    +  +++ G
Sbjct: 418 AMCIES-WARFSLVRMAG 434
 Score =  120 bits (299), Expect = 1e-25
 Identities = 33/295 (11%), Positives = 73/295 (24%), Gaps = 67/295 (22%)

Query: 576 IFSMLLLWARLHRHSQLPQSLASGAALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVI 635
           ++S  ++ A          +               L   +  F +   +AA + V T   
Sbjct: 601 VYSAAMVTALTL------LAFPLLLLHAERISLVFLLLFLQSFLLLHLLAAGIPVTTPGK 654

Query: 636 FWCCLALVLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHNILLLP 695
           +        +           S   +     LL          L+  +L +         
Sbjct: 655 Y--------LSSDSLKDNSDVSSAPLVFKEVLL----------LMFLSLTEGPMPHTTRK 696

Query: 696 VLLVALQQTYK------------LCDVYGTSARKFSVRLVHVYKIIM-TIFLARMFFFYQ 742
           V LV+                    +     + K        ++ +     +A   F+  
Sbjct: 697 VFLVSSLLPAIAKQIDPSCWFPGFMERRDKESSKTPCPFTVPWQAVSAWALMATQTFYST 756

Query: 743 GNSNSLSTIDLTPGYIGQTNYNPSIV---AIFVTLNTYSADIHAFLYLVVHTLRS---DL 796
           G+      I     ++G    + S     A+ V  NT+++ +   +   +  L     + 
Sbjct: 757 GHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCES 816

Query: 797 RSVGIMQLHPPYSI------------------------AADSLIAPLYAALIMLP 827
           + +   Q  P                               +L+      L +L 
Sbjct: 817 QGLRKRQQPPGNEADARVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFILG 871
>ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
 gb|AAF24617.1|AC010870_10 (AC010870) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
          Length = 921

 Score =  408 bits (1040), Expect = e-112
 Identities = 118/639 (18%), Positives = 205/639 (31%), Gaps = 128/639 (20%)

Query: 1   MEQHKSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPP 60
           +++ ++WL   +G+    +    +F I F              P       +    +   
Sbjct: 39  LKRRETWL-VVLGVALHAVYMLSIFDIYF------------KTPIVHGMDPVPPRFSE-- 83

Query: 61  PAYDSFVLLLVDALRDDFPDATSMPVAY---------SRACEKLKLHVDIPTVTMPRLKS 111
           P     VLL+ D LR D          Y                  H   PT + P   +
Sbjct: 84  PPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVA 143

Query: 112 ITTGTLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLF----------- 160
           I  G   +   +           DS  ++     R     G    + +F           
Sbjct: 144 IIAGFYEDPSAVTKGWKANPVEFDSVFNQS----RHTFAFGSPDIIPIFCSALPHSTWNS 199

Query: 161 -PSEFTRQVENHDSF-YVNDFYEGDRNVTK-TLETELER---SDWSLLILHYLGLDHIGH 214
            P E+        SF     F + +  + +   + +L+     D  ++ LH LG D  GH
Sbjct: 200 YPHEY-EDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGH 258

Query: 215 VEGNASPRVPLKLKEMDEVVKKILDHKS----FPNVLLMLTGDHGMADGGGHGGNTPAET 270
                S      +K +D++ +++               + T DHGM+D G HG   P  T
Sbjct: 259 AHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNT 318

Query: 271 LVPLYLYYNNCSKTP--------------------------------SASKRYNQIDLAP 298
             PL  +                                              NQ D+AP
Sbjct: 319 DTPLVAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAP 378

Query: 299 TLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLLNKARVKFGHEIVHRSDY 358
            +S LL +  P  S+G L    ++  +   ++ A   N   +LN+   K  +     S +
Sbjct: 379 LMSTLLGLPCPVNSVGNLPLGYMKL-NEAEEVEAVVANTKQILNQLLRK-SYIKSSNSLF 436

Query: 359 YTWYQNATLLHKKLLRPLREGDGGGASQVYYQNAKL--NYMRLQLDGLKVGQL--WLSVI 414
           +  +    L+H      L + D   +++ Y    KL  +   L L+GL   Q   WL ++
Sbjct: 437 FKPF--KPLVHHSF--SLSQIDELISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLM 492

Query: 415 AAVVLNYTSHALDIIMTSSTLYSIL---LLVPISIAVYLTIDVAQALLKIA-----LPPL 466
             + L YT   + + +     YS L   L     ++VY++  +  A+L +       PPL
Sbjct: 493 TVITLGYTGWMIVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPL 552

Query: 467 YTRRLKISIPLPLPLLACY-AIRTL--------------------------TLGSSSFIE 499
           Y   + +++ L   + + Y  IR L                           L   SF E
Sbjct: 553 YHAYIGMTVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTE 612

Query: 500 FEYNTWYYLGNTLILLTAFRT-LRWRITKTNVELNGRHL 537
            +  TW++L   ++        + WR             
Sbjct: 613 RKLYTWFFLIAGVVASILLHFSIPWRSGIPVFVCISCWF 651
 Score =  266 bits (674), Expect = 1e-69
 Identities = 57/314 (18%), Positives = 97/314 (30%), Gaps = 50/314 (15%)

Query: 1   MEQHKSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPP 60
           +++ ++WL   +G+    +    +F I F              P       +    +   
Sbjct: 39  LKRRETWL-VVLGVALHAVYMLSIFDIYF------------KTPIVHGMDPVPPRFSE-- 83

Query: 61  PAYDSFVLLLVDALRDDFPDATSMPVAY---------SRACEKLKLHVDIPTVTMPRLKS 111
           P     VLL+ D LR D          Y                  H   PT + P   +
Sbjct: 84  PPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVA 143

Query: 112 ITTGTLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLF----------- 160
           I  G   +   +           DS  ++     R     G    + +F           
Sbjct: 144 IIAGFYEDPSAVTKGWKANPVEFDSVFNQS----RHTFAFGSPDIIPIFCSALPHSTWNS 199

Query: 161 -PSEFTRQVENHDSF-YVNDFYEGDRNVTK-TLETELER---SDWSLLILHYLGLDHIGH 214
            P E+        SF     F + +  + +   + +L+     D  ++ LH LG D  GH
Sbjct: 200 YPHEY-EDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGH 258

Query: 215 VEGNASPRVPLKLKEMDEVVKKILDHKS----FPNVLLMLTGDHGMADGGGHGGNTPAET 270
                S      +K +D++ +++               + T DHGM+D G HG   P  T
Sbjct: 259 AHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNT 318

Query: 271 LVPLYLYYNNCSKT 284
             PL  +       
Sbjct: 319 DTPLVAWGAGIQYP 332
 Score = 66.5 bits (161), Expect = 2e-09
 Identities = 21/152 (13%), Positives = 52/152 (33%), Gaps = 3/152 (1%)

Query: 671 LQTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVYGTSARKFSVRLVHVYKIIM 730
             + L   L+   L +   +     V   +L +      +   S  +  ++L  V   ++
Sbjct: 720 FYSALAVVLMAWILFENA-SHHSSKVKESSLSENNTEEHITIGSD-ERYLQLSDVRIPLV 777

Query: 731 TIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIFVTLNTYSADIHA-FLYLVV 789
            + L  + FF  GN  S+++ +++  Y   T ++P ++A  +    +   +     +  +
Sbjct: 778 FMVLFNVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAI 837

Query: 790 HTLRSDLRSVGIMQLHPPYSIAADSLIAPLYA 821
             L    R      +     I        +  
Sbjct: 838 TKLVRVPRLGCYFLVILFSDIMTIHFFFLVKN 869
>dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [Mus musculus]
          Length = 391

 Score =  396 bits (1009), Expect = e-109
 Identities = 86/407 (21%), Positives = 137/407 (33%), Gaps = 71/407 (17%)

Query: 8   LVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSFV 67
           L + +G+L  F+  A +F I F   S  V               +  + TP PP     V
Sbjct: 3   LFFALGLLIHFVFFASIFDIYF--TSPLVHG-------------MTPQFTPLPPPAKRLV 47

Query: 68  LLLVDALRDDFPDATSMPVAY---------SRACEKLKLHVDIPTVTMPRLKSITTGTLS 118
           L + D LR D                             H  +PT + P   ++  G   
Sbjct: 48  LFVADGLRADTLYELDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYE 107

Query: 119 NFIDIALNVGHTEQMQDSFLHRLK-----------------QQNRVVSFAGDHTWVKLFP 161
           +   +A          DS  +  K                      V         + F 
Sbjct: 108 DVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDF- 166

Query: 162 SEFTRQVENHDSFY-VNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNAS 220
                   +   F  V DF++  RN  ++L T++      +  LH LG+D  GH    +S
Sbjct: 167 GAHDATKLDTWVFDKVKDFFDAARN-NQSLFTKVNEEK-VVFFLHLLGIDTNGHAHRPSS 224

Query: 221 PRVPLKLKEMDEVVKKILDHK-----SFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLY 275
                 +K++D+ VK+I+               + T DHGM D G HG   P+ETL P  
Sbjct: 225 REYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFV 284

Query: 276 LYYNNCSKTPS-------------------ASKRYNQIDLAPTLSVLLSVEIPTLSIGCL 316
            +        +                     +  NQ D+AP ++ L+ V  P  S+G L
Sbjct: 285 TWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGIL 344

Query: 317 IPEMLQSLSLEHQLYAYFYNAHHLLNKARVKF-GHEIVHRSDYYTWY 362
               L +  L  +  + F NA  +L + +VK    +       +T +
Sbjct: 345 PVGYLNNTGL-FKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPF 390
>gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melanogaster]
          Length = 919

 Score =  358 bits (910), Expect = 3e-97
 Identities = 113/893 (12%), Positives = 250/893 (27%), Gaps = 117/893 (13%)

Query: 7   WLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSF 66
           W +  + +    L    +  I F          +ST+           EL    P  D  
Sbjct: 2   WSIQALVV--HLLLLGSILSIYF----------QSTILSDLEPLSTLRELGLE-PPADRL 48

Query: 67  VLLLVDALRDDFPDATSMP------VAYSRACEKLKLHVDIPTVTMPRLKSITTGTLSNF 120
           V+ +VD LR     A            +             PTVT P   +I  G   + 
Sbjct: 49  VVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDP 108

Query: 121 IDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTR----QVENHDSFYV 176
                    T     S    +  ++R           K+F    T     + E      +
Sbjct: 109 -------AATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFARSDI 161

Query: 177 NDFYEGDRNVTKTLETELERSDW---------SLLILHYLGLDHIGHVEGNASPRVPLKL 227
           +D    D+     +   +               +  ++   +D   HV    S     KL
Sbjct: 162 SDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKL 221

Query: 228 KEMDEVVKKILDHKS----FPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNNCSK 283
                 +++  +             ++T D+G++    HGG        P  L+     +
Sbjct: 222 NYTQRGIRQTYELFESVFNDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKR 278

Query: 284 ---------------TPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEH 328
                                +  QI LAP +S L+ +  P  ++  +    L + S+++
Sbjct: 279 SAPNPGQNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFL-NTSVQY 337

Query: 329 QLYAYFYNAHHLLNKARVKFGHEIVHRSDYYTWYQNATLLHKKLLRPLREGD-GGGASQV 387
           +L     NA  LL +AR+            Y        L    +    +      A + 
Sbjct: 338 ELQVLHLNAMQLLAQARILIKRHED--GILYLLLPKFESLGSAEIENYPQIIKYLVAKEQ 395

Query: 388 YYQNAKLN--YMRLQLDGLKVGQLW--LSVIAAVVLNYTSHALDIIMTSSTLYSILLLVP 443
           Y +  K++    +L  + ++    +  L ++ A   +Y      +++  +   +      
Sbjct: 396 YEEALKVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWFYLLLVRLARESNHPKSER 455

Query: 444 ISIAVYLTIDV-------AQALLKIALPPLYTRRLKISIPLPLPLLAC------------ 484
                + T+ +        + ++   +P L    L +   + +  LA             
Sbjct: 456 KGYLTWTTLMMCLGGLVLLELMILQRVPHLTAFYLLLPFGILILALAERPCQDRDLMCQF 515

Query: 485 --YAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRITKTNVELNGRHLYTIAS 542
               +  + +     I   ++  +     L ++       +      +      ++ ++ 
Sbjct: 516 PVLHLVGIVMPGVLLILMAFHNSHIGLLYLPIVCLNNRRAFFRPSLKLIFWLALVFLLSG 575

Query: 543 TCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLLLWARLHRHSQ---LPQSLASG 599
             L +    L  +     +   +      S   I S++      H+HS    +    A  
Sbjct: 576 ILLVKQSASLHFITDTIGVYIGNSHVVYFSM--ILSIIRPLILGHQHSTRVWIVNMAALL 633

Query: 600 AALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFWCCLALVLMLGYRAA-----LPQ 654
              + +Y +           V +   + L+             +   G +       L  
Sbjct: 634 VTAYGIYQWDADQPVC--TYVYAACWSYLL--------FAFLSIPYSGTKDLRRRLELII 683

Query: 655 AHSFGKVPPTGALLQLLQTNL--TSSLLLAALLQRVHNILLLPVLLVALQQT---YKLCD 709
            +           +  L   +  T  +L   L +   +   L   +   QQ     +   
Sbjct: 684 FNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESFSYANLKDAIANQQQNNQGLEESR 743

Query: 710 VYGTSARKFSVRLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVA 769
               +     VR  + Y  ++ ++L    FF  G+     T       +    ++  ++ 
Sbjct: 744 NESPNNPLEHVRQSYRYAALILLYLYI-SFFGTGHWFFNFTFKPMTSRLFFPQFHLHMLV 802

Query: 770 IFVTLNTYSADIHAFLYL-VVHTLRSDLRSVGIMQLHPPYSIAADSLIAPLYA 821
            F+ L  +   I     +  + +          + L       +      +  
Sbjct: 803 AFILLKIFIPSIIVMSSIYALVSFGRKNVRSIFICLFLMNDAMSLYFCYFVIN 855
 Score =  348 bits (885), Expect = 2e-94
 Identities = 78/528 (14%), Positives = 157/528 (28%), Gaps = 76/528 (14%)

Query: 7   WLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSF 66
           W +  + +    L    +  I F          +ST+           EL    P  D  
Sbjct: 2   WSIQALVV--HLLLLGSILSIYF----------QSTILSDLEPLSTLRELGLE-PPADRL 48

Query: 67  VLLLVDALRDDFPDATSMP------VAYSRACEKLKLHVDIPTVTMPRLKSITTGTLSNF 120
           V+ +VD LR     A            +             PTVT P   +I  G   + 
Sbjct: 49  VVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDP 108

Query: 121 IDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTR----QVENHDSFYV 176
                    T     S    +  ++R           K+F    T     + E      +
Sbjct: 109 -------AATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFARSDI 161

Query: 177 NDFYEGDRNVTKTLETELERSDW---------SLLILHYLGLDHIGHVEGNASPRVPLKL 227
           +D    D+     +   +               +  ++   +D   HV    S     KL
Sbjct: 162 SDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKL 221

Query: 228 KEMDEVVKKILDHKS----FPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNNCSK 283
                 +++  +             ++T D+G++    HGG        P  L+     +
Sbjct: 222 NYTQRGIRQTYELFESVFNDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKR 278

Query: 284 ---------------TPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEH 328
                                +  QI LAP +S L+ +  P  ++  +    L + S+++
Sbjct: 279 SAPNPGQNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFL-NTSVQY 337

Query: 329 QLYAYFYNAHHLLNKARVKFGHEIVHRSDYYTWYQNATLLHKKLLRPLREGD-GGGASQV 387
           +L     NA  LL +AR+            Y        L    +    +      A + 
Sbjct: 338 ELQVLHLNAMQLLAQARILIKRHED--GILYLLLPKFESLGSAEIENYPQIIKYLVAKEQ 395

Query: 388 YYQNAKLN--YMRLQLDGLKVGQLW--LSVIAAVVLNYTSHALDIIMTSSTLYSILLLVP 443
           Y +  K++    +L  + ++    +  L ++ A   +Y      +++  +   +      
Sbjct: 396 YEEALKVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWFYLLLVRLARESNHPKSER 455

Query: 444 ISIAVYLTIDV-------AQALLKIALPPLYTRRLKISIPLPLPLLAC 484
                + T+ +        + ++   +P L    L +   + +  LA 
Sbjct: 456 KGYLTWTTLMMCLGGLVLLELMILQRVPHLTAFYLLLPFGILILALAE 503
>ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans]
          Length = 348

 Score =  347 bits (883), Expect = 4e-94
 Identities = 75/366 (20%), Positives = 118/366 (31%), Gaps = 51/366 (13%)

Query: 6   SWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDS 65
           SW      +    +    +F + +            T P         +           
Sbjct: 2   SWKFLIASITVHLVLIYSIFDVYY------------TSPLVHGIPPQFINSQE--APAKR 47

Query: 66  FVLLLVDALRDDFPDATSMPVAYSRA------CEKLKLHVDIPTVTMPRLKSITTGTLSN 119
             ++  D LR D  +       Y  +               IPT + P   +I  G   +
Sbjct: 48  IFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITED 107

Query: 120 FIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLF-------PSEFTRQVENHD 172
              +A          DS  +R           G    V LF          ++   E+  
Sbjct: 108 ISAVAKGWKKNPVQFDSVFNRSSYS----WMWGSPDIVNLFDDLPNAESFSYSADEEDFA 163

Query: 173 SFYVNDFYEGDRNVTKTLETELE------------RSDWSLLILHYLGLDHIGHVEGNAS 220
           S   ++    D+ V +  E  LE            R   S+  LH LG+D  GH     S
Sbjct: 164 SKDASNL---DKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMS 220

Query: 221 PRVPLKLKEMDEVVKKILDHKS----FPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYL 276
            +    +K +D  ++K+               + T DHGM D G HG  +  E L P   
Sbjct: 221 RQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVA 280

Query: 277 YYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYN 336
           +     +        NQIDLAP +S L+   IP  S+G L  +M+ S    ++  A   N
Sbjct: 281 WGAGVKQG-GPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEAN 339

Query: 337 AHHLLN 342
              ++N
Sbjct: 340 FKQVIN 345
>gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melanogaster]
          Length = 1077

 Score =  333 bits (847), Expect = 7e-90
 Identities = 106/403 (26%), Positives = 165/403 (40%), Gaps = 52/403 (12%)

Query: 6   SWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTV----PEGRPTALL--------- 52
           ++L   I +      G +LF  GF  A  S  E  +             L          
Sbjct: 4   TYLFVLIWLAFLISSGVMLFSRGFLLARVSKTETSTCRRLSTNPNAEYVLTDEVVNEIFK 63

Query: 53  --GMELTPPPPAYDSFVLLLVDALRDDFPDATS--------------MPVAYSRA---CE 93
                     P     ++L+VDAL+ +F    +              +     +      
Sbjct: 64  DVNASSNLCLPQKSKVIVLVVDALKYEFGLYRANATDPLPYENKLVVLQELLQQNPDHAR 123

Query: 94  KLKLHVDIPTVTMPRLKSITTGTLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGD 153
            ++   D PT T+ RLK +TTG+L  FIDI  N    E  +D+ + ++ + +  V F GD
Sbjct: 124 LMRFRADPPTTTLQRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQIVKNDLPVVFLGD 183

Query: 154 HTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIG 213
            TW  L+P  F R   ++ SF + D    D  + K L  ELE  DW +L+ H+LG+DH G
Sbjct: 184 STWTDLYPHRFKRSY-SYPSFDIFDLDSVDNEILKHLPKELESKDWQVLVAHFLGVDHCG 242

Query: 214 HVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGGGHGGNTPAETLVP 273
           H  G     +  KL EM+EV++ ++      +  L++ GDHGM   G HGG+T  ET   
Sbjct: 243 HKHGPMHEEMARKLGEMNEVIRSVVAAM-DNDTTLLVMGDHGMTASGDHGGDTDDETNAL 301

Query: 274 LYLYYNNCSKTPSASKR-----YNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEH 328
           L+ Y     +              QIDL PTL+ +L V IP  ++G +      + ++  
Sbjct: 302 LFAYS-KQHRFYGNDSGSDSEMLQQIDLVPTLATILGVPIPYSNLGLV------NFNIVP 354

Query: 329 QLYAYFYNAHHLLNKARVKFGHEIVHRSDYYTWYQNATLLHKK 371
            L     N    L        H   +    Y ++    L +K+
Sbjct: 355 DLRVPHLNKFQTL------LLHSWQNAQQIYRYFFQYALENKR 391
 Score =  111 bits (277), Expect = 5e-23
 Identities = 26/151 (17%), Positives = 46/151 (30%), Gaps = 14/151 (9%)

Query: 658 FGKVPPTGALLQLLQTNLTSSLLLAALLQRVHNILLLP------VLLVALQQTYKLCDVY 711
                P    L  + +  +  +     L  V  +LL P      V+ VA+          
Sbjct: 795 RRSHIPVVYGLATVYS--SIVIAFGVFLALVMIVLLEPRASIGLVVCVAVGAILLSVHSI 852

Query: 712 GTSARKFSVRLVHV---YKIIMTIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNP--- 765
                  S           ++    LA   FF   +  +LS I+    ++G+T       
Sbjct: 853 LRYRTATSFESCVQPTFTALVGWFLLAHFCFFATSHQTTLSQIEWRAAFVGRTTGIGQSN 912

Query: 766 SIVAIFVTLNTYSADIHAFLYLVVHTLRSDL 796
            +    V LNT+   I  F    + +  +  
Sbjct: 913 LVSGALVILNTFCGPIFFFCMYSLLSTETFS 943
 Score = 43.9 bits (103), Expect = 0.013
 Identities = 11/64 (17%), Positives = 22/64 (34%), Gaps = 6/64 (9%)

Query: 810  IAADSLIAPLYAALIMLPAAFYLCLLVGFRYHLFIYSVFSPKVLYDCYTVLVFYLVFLVT 869
            +A    +         + A    C       HL ++ +F+P+ +Y+     V     +V 
Sbjct: 1000 LATQFFMLQGLKIFCAMLACTIHC------RHLMVWKIFAPRFIYEALATFVSLPALIVG 1053

Query: 870  SLYF 873
             L  
Sbjct: 1054 YLLV 1057
>ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thaliana]
 gb|AAF18652.1| (AC006592) unknown protein [Arabidopsis thaliana]
          Length = 897

 Score =  332 bits (843), Expect = 2e-89
 Identities = 118/371 (31%), Positives = 179/371 (47%), Gaps = 29/371 (7%)

Query: 8   LVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKE---STVPEGRPTALLGMELTPPPPAYD 64
           +    G+L   + G  +F+ GFFP   +++      S       ++L+  E     P   
Sbjct: 13  IFTVAGILL-QIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKL 71

Query: 65  SFVLLLVDALRDDFPDATS---------MPVAYSRA------CEKLKLHVDIPTVTMPRL 109
             +  ++D L  +F                + Y+++                PTVTMPRL
Sbjct: 72  RLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRL 131

Query: 110 KSITTGTLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVE 169
           K++ +G +  F+D+A N      + D+ L +  +    +   GD TW+KLFP  F R  +
Sbjct: 132 KAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMRH-D 190

Query: 170 NHDSFYVNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKE 229
              SF+V D  + DRNV++ L  EL   DW+LLILHYLGLDH+GH  G  SP +P KLKE
Sbjct: 191 GVSSFFVKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVGHTGGRNSPLMPAKLKE 250

Query: 230 MDEV-----VKKILDHKSFPN-VLLMLTGDHGMADGGGHGGNTPAETLVPLYLYY--NNC 281
           MD++     ++ ++D        LL++  DHGM + G HGG++  ET   +      +N 
Sbjct: 251 MDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLMLFIGLNSNI 310

Query: 282 SKTPSASKRYN-QIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHL 340
           S   SA+     Q+DLAPTL++L  V IP  ++G L+P  L SL    QL A   N+  L
Sbjct: 311 SDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQL 370

Query: 341 LNKARVKFGHE 351
           L     +    
Sbjct: 371 LRLMLAQIQSS 381
 Score = 65.7 bits (159), Expect = 3e-09
 Identities = 56/324 (17%), Positives = 113/324 (34%), Gaps = 25/324 (7%)

Query: 480 PLLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRITKTNVEL-----NG 534
            + A   I  +++GSSS +E E+  W+++ +T  LL  F+T +       + +      G
Sbjct: 519 FIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHLLLLFKTAKSFKISKGMNILRDFKFG 578

Query: 535 RHLYTIAS--TCLWQMR---KVLVVLMLLTLMRYIHR--LQAIRSTVVIFSMLLLWARLH 587
                + S        +       +  +   +       ++ I+   +I  + L    L 
Sbjct: 579 SIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLISIILVIGLGLYTLF 638

Query: 588 RHSQLPQSLASGAALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFWC---CLALVL 644
           R     + +   A  F    F  L     + D  S      +   ++ +      +   L
Sbjct: 639 RTGSNRKGVRILAFGFSTCGFLVLLHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASL 698

Query: 645 MLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLVALQQT 704
           +L + A         +V     L+                      I   P+LL+ LQ  
Sbjct: 699 VLPWSALNKDKSFLAEVGDCLYLIGSAY----ILCWCLLQQLLQQPINSGPILLLLLQIL 754

Query: 705 YKLCDVYGTSARKFSVRLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYN 764
                           ++    +I    ++     F  GNSN+L+TID+   +IG ++++
Sbjct: 755 ------AILCLSSSDFQVNEWVEITALYYMGMAGHFALGNSNTLATIDVAGAFIGISSHS 808

Query: 765 PSIVAIFVTLNTYSADIHAFLYLV 788
             +  I + + TY++ +   L LV
Sbjct: 809 TILSGILMFMITYASPMLFLLSLV 832
>ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involved in the attachment
           of glycosylphosphatidylinositol (GPI) anchors to
           proteins.; Las21p [Saccharomyces cerevisiae]
 sp|P40367|YJG2_YEAST HYPOTHETICAL 94.9 KD PROTEIN IN MRPL8-NUP82 INTERGENIC REGION
 pir||S50810 probable membrane protein YJL062w - yeast (Saccharomyces
           cerevisiae)
 emb|CAA84061.1| (Z34288) HRC830 [Saccharomyces cerevisiae]
 emb|CAA89353.1| (Z49337) ORF YJL062w [Saccharomyces cerevisiae]
          Length = 830

 Score =  331 bits (841), Expect = 3e-89
 Identities = 100/492 (20%), Positives = 185/492 (37%), Gaps = 66/492 (13%)

Query: 389 YQNAKLNYMRLQLDGLKVGQLWLSVIAAVVLNYTSHALDIIMTSST---LYSILLLVPIS 445
             + K N+M L       G++ L    A  +    + +   +T S     Y +L L  + 
Sbjct: 354 LASMKENFMHLWKLSDHHGEVALDDFTAEDIYTKMYTIQETLTKSATNYNYPLLTLAFVG 413

Query: 446 IAVYLTIDVAQALLKIALPPLYTRRLKISIPLPLPLLACYAIRTLTLGSSSFIEFEYNTW 505
             + +TI     LL+ + P  +  R+         +L    I  ++  +SSFIE E+  W
Sbjct: 414 FLI-ITIIAIYVLLRYSGPDFWQLRVSSLS-----VLLVSIILGVSTFASSFIEEEHQLW 467

Query: 506 YYLGNTLILLTAFRTLRWRITKTNVELNGRHLYTIAS---TCLWQM--RKVLVVLMLLTL 560
           ++      ++TAF  +   + + NV +  R    +A       W    +K +   ++  L
Sbjct: 468 WW------IVTAFSAVPLFVYRLNVLIIVRWFIMMACVRSIKFWNNSGQKFIYSNVMSNL 521

Query: 561 MRYIHRLQAIRSTVVIFSMLLLWARLHRHSQLPQSLASGAALFMVYCFRGLNG-QVLFFD 619
           +      +   + +    +++  A       +  ++  G        +  +NG Q     
Sbjct: 522 LNQNPSWKWCLNMLTFLVLIMASAGFQVLHFIVTTILVGLCFTYKISWEIVNGNQAEIPL 581

Query: 620 VPSHMAAKLMVPTLVIFWCCLALVLMLGYRAALPQAHSFGKVP--PTGALLQLLQTNLTS 677
               + AK+           LA V    +   +       K+       L++ ++  +T 
Sbjct: 582 FMHDLLAKIDFAPTESNLIVLARVFFQAWAIVVISRLVLTKLKVLNKNYLIKDMKVYITI 641

Query: 678 SLLLAALLQRVHNILLLPVLL---VALQQTYKLCDVYGTSARKFSVRLVHVYKIIMTIFL 734
            L+     Q +   L+  +L        Q      +  TS   FS         ++++ L
Sbjct: 642 LLMFQTSSQNIGQFLVFQILESQIFYFFQNIPTASLTSTSKIYFS--------NLVSLIL 693

Query: 735 ARMFFFYQGNSNSLSTIDLTPGYIGQTN-YNPSIVAIFVTLNTYSADIHAFLYLVVHTLR 793
               FF  G +NS+STIDL   Y G ++ YN  +V I +++  ++  I+  +        
Sbjct: 694 QNFTFFQFGGTNSISTIDLGNAYHGVSSDYNIYVVGILMSVANFAPAIYWSM-------- 745

Query: 794 SDLRSVGIMQLHPPYSIAADSLIAPLYAALIM---LPAAFYLCLL--------VGFRYHL 842
                        P+SI   S+ A +     +   LPA  Y C+         V  R+HL
Sbjct: 746 ------------LPWSINYASIPAQVKLQTFIRSKLPAFTYHCIFGTCLMTACVVLRFHL 793

Query: 843 FIYSVFSPKVLY 854
           FI+SVFSPK+ Y
Sbjct: 794 FIWSVFSPKLCY 805
 Score =  302 bits (768), Expect = 1e-80
 Identities = 115/362 (31%), Positives = 172/362 (46%), Gaps = 47/362 (12%)

Query: 17  AFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSFVLLLVDALRD 76
           A L   +LF+  FFP    +          +   L           +   V +++DALR 
Sbjct: 12  AQLLAILLFIFAFFPRKIVLTGIS-KQDPDQDRDLQRDR------PFQKLVFVIIDALRS 64

Query: 77  DFPDATS-------MPVAYSRACEKLKLHVDIPTVTMPRLKSITTGTLSNFIDIALNVG- 128
           DF   +             +          + PTVT+PRLKSITTG+  +FID+ LNV  
Sbjct: 65  DFLFDSQISHFNNVHQWLNTGEAWGYTSFANPPTVTLPRLKSITTGSTPSFIDLLLNVAQ 124

Query: 129 ----HTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDR 184
               +     DS+L +  Q N  + F GD TW+KLFP ++    +   SF+V+DF + D 
Sbjct: 125 DIDSNDLSEHDSWLQQFIQHNNTIRFMGDDTWLKLFPQQWFDFADPTHSFFVSDFTQVDN 184

Query: 185 NVTKTLETEL--ERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVK----KIL 238
           NVT+ L  +L  E + W + ILHYLGLDHIGH +G  S  +  K +EMD ++K    ++L
Sbjct: 185 NVTRNLPGKLFQEWAQWDVAILHYLGLDHIGHKDGPHSKFMAAKHQEMDSILKSIYDEVL 244

Query: 239 DHKSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNNCSKTPSASKRYN------ 292
           +H+   + L+ + GDHGM + G HGG++  ET   L       ++      + N      
Sbjct: 245 EHEDDDDTLICVLGDHGMNELGNHGGSSAGETSAGLLFLSPKLAQFARPESQVNYTLPIN 304

Query: 293 --------------QIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAH 338
                         QID+ PT++ L  + IP  S+G +IP+ LQ L    +L +   N  
Sbjct: 305 ASPDWNFQYLETVQQIDIVPTIAALFGMPIPMNSVGIIIPDFLQLLPN--KLASMKENFM 362

Query: 339 HL 340
           HL
Sbjct: 363 HL 364
>ref|NP_495820.1| (NM_063419) Yeast YJ10 like [Caenorhabditis elegans]
 pir||T21487 hypothetical protein F28C6.4 - Caenorhabditis elegans
 emb|CAA92675.1| (Z68315) Similarity to Yeast hypothetical protein YJ10
           (SW:YJ10_YEAST)~cDNA EST yk160e12.5 comes from this
           gene~cDNA EST yk160e12.3 comes from this gene~cDNA EST
           yk317h4.3 comes from this gene~cDNA EST yk317h4.5 comes
           from this gene [Caenorhabditis ele>
          Length = 795

 Score =  321 bits (816), Expect = 3e-86
 Identities = 102/390 (26%), Positives = 173/390 (44%), Gaps = 38/390 (9%)

Query: 2   EQHKSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPP 61
           ++ K W+   + +    L                  +   T P        G + +   P
Sbjct: 54  KKGKFWISRVLVVCACALLVYSF----------VALDITPTPPTEEFGFKDGNQESSSSP 103

Query: 62  AYDSFVLLLVDALRDDFPDATSMPVAYS------RACEKLKLHVDIPTVTMPRLKSITTG 115
                V +++DA R  F  ++  P++++      ++ +    +  +PTVT+PR+ +  TG
Sbjct: 104 ---RLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTG 160

Query: 116 TLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFY 175
           TL +F  +  N+   E    +++ R+++  + V F GD TW++L P  F +  E   SF+
Sbjct: 161 TLPSFGTVLTNLATAEMKTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEK-FEGVTSFF 219

Query: 176 VNDFYEGDRNVTKTLETEL--ERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEV 233
           V+D+ + D NVT+ L+TEL      W  LILHYLGLDHIGH  G +S ++P KLKEMD+V
Sbjct: 220 VSDYTDVDNNVTRHLDTELSNTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDV 279

Query: 234 VKKILDHKS-----FPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNNCSKT---- 284
           + +I  +            L++ GDHGM   G HGG +P ET VP+ ++     +     
Sbjct: 280 IGRIHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKNY 339

Query: 285 ------PSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAH 338
                      R  QID++ T+  + ++ IP  S G  +         E+          
Sbjct: 340 GNQDDSLKQPPRIEQIDVSSTIFDVFNMPIPIESYGISLINYFSDDEEEY-FEKQHNQFR 398

Query: 339 HLLNKARVKFGHEIVHRSDYYTWYQNATLL 368
            ++    +          DY   +  + L 
Sbjct: 399 RIVQAKHLAISDICDENCDYSDKFIKSALK 428
 Score =  286 bits (726), Expect = 9e-76
 Identities = 94/535 (17%), Positives = 169/535 (31%), Gaps = 125/535 (23%)

Query: 357 DYYTWYQNATLLHKKLLRPLREGDGG------GASQVYYQNAKLNYMRLQLDGLKV---- 406
           D +            L+    + +           +   Q   L    +  +        
Sbjct: 363 DVFNMPIPIESYGISLINYFSDDEEEYFEKQHNQFRRIVQAKHLAISDICDENCDYSDKF 422

Query: 407 ----GQLWLSVIAAVVLNYTSHALDIIMTSSTLYSILLLVPISIAVYLTIDVAQALLKIA 462
                + W   + + ++   S         +     L +    + V LT+ +        
Sbjct: 423 IKSALKKWFLTVQSELIGSASE------VPNK---SLGVCVFLLLVALTLSM-------- 465

Query: 463 LPPLYTRRLKISIPLPLPLLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLR 522
              L+   L  S      +        +T  +SS IE E+  WYYLG+T++ + A R  +
Sbjct: 466 --GLWNLHLSKSDFFIFLI-------NITYFASSLIEEEHEIWYYLGSTVVAIRALRNFK 516

Query: 523 -WRITKTNVELNGRHLYTIASTCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLL 581
            W  T+         L+ IA +     R+                 + I  +    S+L 
Sbjct: 517 IWNKTEVKSIFFLAFLHRIACSYTQSTRR-----------------RWIMDS----SLLP 555

Query: 582 LWARLHRHSQLPQSLASGAALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFWCCLA 641
                      P +L +    + +     +      F +  +  +K  +   ++    L 
Sbjct: 556 PSIFSDTLDFQPNNLNTILNEYPII----VILTCSLFWMYGYKQSKFHIILPMVSHF-LR 610

Query: 642 LVLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLVAL 701
           L  +  +   L        + P       +                    LLL ++ V+ 
Sbjct: 611 LFELTQFNEVLMH-FIRLSILPISYSTGSVLAGC--------------LPLLLAIVPVSQ 655

Query: 702 QQTYKLCDVYGTSARKFSVRLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGYIGQT 761
                +    G          ++    +  + L    FFY GNSNSLST+ LT  Y+G +
Sbjct: 656 ILLLLVIYNMGKL-----FSKLN-LGSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLS 709

Query: 762 NYNPSIVAIFVTLNTYSADIHA--------FLYLVVHTLRSDLRSVGIMQLHPPYSIAAD 813
           +Y P +V + + L T+S  I             L+ H                 Y I++ 
Sbjct: 710 SYQPILVGLQLMLYTFSGPILFLCGCNASSCTSLLNHLFS--------------YRISSM 755

Query: 814 SLIAPLYAALIMLPAAFYLCLLVGFRYHLFIYSVFSPKVLYDCYTVLVFYLVFLV 868
                                L  F+ HLFI+SV+SPKV+YD   V+ F L+ L+
Sbjct: 756 CTSLIC---------------LYIFQNHLFIWSVYSPKVVYDMAHVIFFGLIGLL 795
>ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thaliana]
 dbj|BAB10512.1| (AB005238) gene_id:MKP11.10~unknown protein [Arabidopsis thaliana]
          Length = 884

 Score =  321 bits (815), Expect = 4e-86
 Identities = 54/402 (13%), Positives = 128/402 (31%), Gaps = 30/402 (7%)

Query: 480 PLLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTA-FRTLRWRITKTNVELNGRHLY 538
             L    IR  +  S+S+I  E     +L  T  L+   +  +R  + K           
Sbjct: 504 FTLFIVTIRACSFLSNSYILEEGKVANFLLATTGLIKLRYSVMRKTMRKEAFMFLAMVFV 563

Query: 539 TIASTCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLLLWARLHRHSQLPQSLAS 598
              S  +   ++      + +          +       +                S+  
Sbjct: 564 LRVSIDIGLTKQAATSQFMSS------SPSWMLGI----APDHPALTYAIEIAPILSVVI 613

Query: 599 GAALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIF-----WCCLALVLMLGYRAALP 653
              +  V   +  N  V        + + L+  T            + LV +      L 
Sbjct: 614 LICVLYVAIAKAPNEGV---WKYVTVGSMLLQVTGGRNRIPQTVYVIGLVQLC----LLA 666

Query: 654 QAHSFGKVPPTGALLQLL--QTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVY 711
            A  F         ++ +   +  +S ++L +  Q     L+  V         +  +  
Sbjct: 667 SARMFCTEKDKNWAIRTVALVSACSSPIILLSGKQGSMLALVYLV-AGYCIMRLEGVERR 725

Query: 712 GTSARKFSVRLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIF 771
             S  +     ++   ++    L+   FF  G+  +   +     ++G   +     AI 
Sbjct: 726 TKSDGQSKFSKLNPLCVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLIRQAIL 785

Query: 772 VTLNTYSADIHAFLYLVVHTLRSDLRSVGIMQLHPPYSIAADSLIAPLYAALIMLPAAFY 831
           +T+ T+   I   ++ +   +    ++         + +    ++  + +A      A  
Sbjct: 786 LTIETFGFSIILSVFGLPLLIPFHSQTPQ-AHGEKRHQLFQMYMLFGVISAT--TVTATI 842

Query: 832 LCLLVGFRYHLFIYSVFSPKVLYDCYTVLVFYLVFLVTSLYF 873
           LC +   R HL ++ +F+PK ++D   +++  L+  + S Y+
Sbjct: 843 LC-VTIQRRHLMVWGLFAPKFVFDVVDLILTDLLICLASAYY 883
 Score =  270 bits (684), Expect = 8e-71
 Identities = 75/302 (24%), Positives = 127/302 (41%), Gaps = 29/302 (9%)

Query: 1   MEQHKSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVP---EGRPTALLGM--E 55
           ++  K   +  +G L       ++F  GF      +    +           +       
Sbjct: 5   LKNKK---LTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSPCLASPRSNHDS 61

Query: 56  LTPPPPAYDSFVLLLVDALRDDFPDATSMPVAYSRACEKLKLHVDIPTVTMPRLKSITTG 115
            + P P  D   +L             ++  A   + +  K   D PT ++ RLK +TTG
Sbjct: 62  SSEPKPWMDKLTIL------------QTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTG 109

Query: 116 TLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFY 175
            L  FIDI  + G    ++D+F+++L    + +   GD TW +LFP++F +      SF 
Sbjct: 110 GLPTFIDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSY-PFPSFN 168

Query: 176 VNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVK 235
           V D    D    + L   L + DW +LI H+LG+DH GH+ G  S  +  KL++ + V++
Sbjct: 169 VKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLE 228

Query: 236 KILDHKSFP--------NVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNNCSKTPSA 287
           K+++             N +L++ GDHG    G HGG T  E    ++        T   
Sbjct: 229 KVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVP 288

Query: 288 SK 289
            +
Sbjct: 289 PE 290
>dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:1351629,
           evidence:ISS~phosphatidylinositol glycan, class
           N~putative [Mus musculus]
          Length = 320

 Score =  313 bits (794), Expect = 1e-83
 Identities = 66/311 (21%), Positives = 102/311 (32%), Gaps = 50/311 (16%)

Query: 8   LVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSFV 67
           L + +G+L  F+  A +F I F   S  V               +  + TP PP     V
Sbjct: 3   LFFALGLLIHFVFFASIFDIYF--TSPLVHG-------------MTPQFTPLPPPAKRLV 47

Query: 68  LLLVDALRDDFPDATSMPVAY---------SRACEKLKLHVDIPTVTMPRLKSITTGTLS 118
           L + D LR D                             H  +PT + P   ++  G   
Sbjct: 48  LFVADGLRADTLYELDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYE 107

Query: 119 NFIDIALNVGHTEQMQDSFLHRLK-----------------QQNRVVSFAGDHTWVKLFP 161
           +   +A          DS  +  K                      V         + F 
Sbjct: 108 DVSAVAKGWKENPVESDSLFNERKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDF- 166

Query: 162 SEFTRQVENHDSFY-VNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNAS 220
                   +   F  V DF++  RN  ++L T++      +  LH LG+D  GH    +S
Sbjct: 167 GAHDATKLDTWVFDKVKDFFDAARN-NQSLFTKVNEEK-VVFFLHLLGIDTNGHAHRPSS 224

Query: 221 PRVPLKLKEMDEVVKKILDHK-----SFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLY 275
                 +K++D+ VK+I+               + T DHGM D G HG   P+ETL P  
Sbjct: 225 REYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFV 284

Query: 276 LYYNNCSKTPS 286
            +        +
Sbjct: 285 TWGAGIKFPQN 295
>ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) biosynthesis; Gpi13p
           [Saccharomyces cerevisiae]
 pir||S64782 probable membrane protein YLL031c - yeast (Saccharomyces
           cerevisiae)
 emb|CAA97480.1| (Z73136) ORF YLL031c [Saccharomyces cerevisiae]
          Length = 1017

 Score =  250 bits (633), Expect = 9e-65
 Identities = 121/585 (20%), Positives = 203/585 (34%), Gaps = 80/585 (13%)

Query: 2   EQHKSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPP 61
           + HK +++  + +          F  GF  + + +    S             E +  PP
Sbjct: 30  KNHKFYIILLVFIAILQFISIAFFTRGFLLSRHVLDNISS-----------QNETSKLPP 78

Query: 62  AYDSFVLLLVDALRDDFPDATSMPVAYSRAC------EKLKLH--------------VDI 101
            ++  V+L++DALR DF    +   +                                D 
Sbjct: 79  RFNKAVILVIDALRFDFAIPVNESHSNYNLNYHNNILSLYDSFASDKDASSLLLKFIADP 138

Query: 102 PTVTMPRLKSITTGTLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFP 161
           PT T+ RLK +TTG+L  FID   N   T   +D+FL +L   N+ V FAGD TW+ LF 
Sbjct: 139 PTTTLQRLKGLTTGSLPTFIDAGSNFDGTVIEEDNFLKQLHLANKTVKFAGDDTWMALFH 198

Query: 162 SEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSD-WSLLILHYLGLDHIGHVEGNAS 220
              +      +S  V D    D  V       L++   W ++I H LG+DH+GH  G   
Sbjct: 199 PFLSNDSFPLESLNVWDLDTVDNGVMDYFHDHLQQDKEWDVMIGHMLGIDHVGHKYGPDH 258

Query: 221 PRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNN 280
             +  K  ++D+ +  IL      + LL++ GDHGM   G HGG++  E    L+LY   
Sbjct: 259 FTMREKQIQVDQFIDWILKSIDD-DTLLVILGDHGMDHTGNHGGDSIDELESTLFLYSKK 317

Query: 281 ------------CSKTPSASKR-YNQIDLAPTLSVLLSVEIPTLSIGCLI---------- 317
                                R   QIDL  +L++L+   IP  ++G  I          
Sbjct: 318 PDMWRLKETSNYNIDNLGHDYRSVRQIDLVSSLALLMGQPIPFNNLGWPIDEIARNDREW 377

Query: 318 PEMLQSLSLEHQLYAYFYNAHHLLNKARVKFGHEIVHRSDYYTWYQNATLLHKKLLRPLR 377
            + + S   + QLY      HH  ++        I +        +    L  K  +   
Sbjct: 378 SQFVNSAISQLQLYKDTMQIHHGNDEILEPLAKNISNTPPTSDP-EKFVKLGHKYQKVFL 436

Query: 378 EGDGGG----ASQVYYQNAKLNYMRLQLDGLKVGQLWLSVIAA--VVLNYTSHALDIIMT 431
           +                   L    L L  L      +  I    +V  +    + +++ 
Sbjct: 437 QTCEELWAKFDYYSIATGITLLATSLVL--LISITKLIPSIVVNQMVPEFVPGIIIMVLV 494

Query: 432 SSTLYSILLLV-----------PISIAVYLTIDVAQALLKIALPPL-YTRRLKISIPLPL 479
           ++  +  +  V              +A  + I +   +         +            
Sbjct: 495 TNLCFHGIFYVYQQPSFVDQFWGTLLATAIGIIIGCYITIFDRYNFIWIAMRLGETLADY 554

Query: 480 PLLACY---AIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTL 521
                     I  L   S+SF  +E     +L +T  +LT +  +
Sbjct: 555 WSRIAVMFMIIHALLFTSNSFTIWEDRIVAFLLSTFGMLTLYEFV 599
 Score = 97.6 bits (241), Expect = 8e-19
 Identities = 38/209 (18%), Positives = 76/209 (36%), Gaps = 16/209 (7%)

Query: 674  NLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVYGTSARKFSVRLVHVYKIIMTIF 733
             L  ++L++ LL       L   L+     +                 +           
Sbjct: 814  LLVINVLISILLFNKPLAQLSYFLMCNQLLSILEIIDLLKLKENIIGPIALGLLSYQH-- 871

Query: 734  LARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSI-VAIFVTLNTYSADIHAFLYLVVHTL 792
                 FF  G+  ++ ++    G++  +         I + LNT+   I   L + + TL
Sbjct: 872  -----FFTTGHQATIPSVQWDIGFM-LSEKVTFPFTQIAIILNTFGPHILVSLSVALLTL 925

Query: 793  RSDLRSVGIMQLHPPYSIAADSLIAPLYAALIMLPAAFYLCLLVGFRYHLFIYSVFSPKV 852
             S    V   Q      I ++  I   Y  ++ L +  +   +  FR HL ++ +F P+ 
Sbjct: 926  WSQPPDVLKPQTLLG-RIVSNCGILLTYNTILCLSSFIW---VTHFRRHLMVWKIFCPRF 981

Query: 853  LYDCYTVLVFYLVFLVTSLYF---KLFKH 878
            ++   +++V  LV    ++ F   +L KH
Sbjct: 982  IFASLSLIVTQLVVTFGTIAFASGRLIKH 1010
>dbj|BAB55130.1| (AK027465) unnamed protein product [Homo sapiens]
          Length = 549

 Score =  247 bits (627), Expect = 5e-64
 Identities = 83/306 (27%), Positives = 135/306 (43%), Gaps = 25/306 (8%)

Query: 568 QAIRSTVVIFSMLLLWARLHRHSQLPQSLASGAALFMVYCFRGLNGQVLFFDVP-SHMAA 626
           +A  S +   S+L+++  + R        A    L  VYC+R   G V F   P S   +
Sbjct: 260 KAELSVLAALSLLVVFVLVQRGCSPVSKAALALGLLGVYCYRAAIGSVRFPWRPDSKDIS 319

Query: 627 KLMVPTLVIFWCCLALVLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQ 686
           K ++    ++   L  +L  G +  L               L  + + L   +LLAALL 
Sbjct: 320 KGIIEARFVYVFVLG-ILFTGTKDLLKSQVIAADFKLKTVGLWEIYSGL---VLLAALLF 375

Query: 687 RVHNILLLPVLLVALQQTYKLCDVYGTSARKFSVRLVHVYKIIMTIFLARMFFFYQGNSN 746
           R HN   LPVL  +L     +        R  +  +      +M  +  + FF++QGNSN
Sbjct: 376 RPHN---LPVLAFSLLIQTLMTKFIWKPLRHDAAEIT-----VMHYWFGQAFFYFQGNSN 427

Query: 747 SLSTIDLTPGYIGQTNYNPSIVAIFVTLNTYSADIHAFLYLVVHTLRSDLRSVGIMQLHP 806
           +++T+D++ G++G   Y      +     TY+  +    +L VH L S+ RS        
Sbjct: 428 NIATVDISAGFVGLDTYVEIPAVLLTAFGTYAGPVLWASHL-VHFLSSETRSG------- 479

Query: 807 PYSIAADSLIAPLYAALIMLPAAFYLCLLVGFRYHLFIYSVFSPKVLYDCYTVLVFYLVF 866
               +A S     YA +  +P   Y+ L+   RYHLFI+SVFSPK+LY+   +L+   V 
Sbjct: 480 ----SALSHACFCYALICSIPVFTYIVLVTSLRYHLFIWSVFSPKLLYEGMHLLITAAVC 535

Query: 867 LVTSLY 872
           +  +  
Sbjct: 536 VFFTAM 541
 Score = 85.9 bits (211), Expect = 2e-15
 Identities = 34/129 (26%), Positives = 52/129 (39%), Gaps = 18/129 (13%)

Query: 411 LSVIAAVVLNYTSHALDIIMTSSTLYSILLLVPISIAVYLTIDV-AQALLKIALPPLYTR 469
           L     +++    H +      S+ Y       +S      + V A ALL + +  L   
Sbjct: 40  LLFYLVILVLSAVHVIVCTSAESSCY----FCGLSWLAAGGVMVLASALLCVIVSVLTNV 95

Query: 470 RLKISIP-------------LPLPLLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLT 516
            +  + P             L L +L   A   L+LG+SSF+E E+ TWY+L NTL L  
Sbjct: 96  LVGGNTPRKNPMHPSSRWSELDLLILLGTAGHVLSLGASSFVEEEHQTWYFLVNTLCLAL 155

Query: 517 AFRTLRWRI 525
           +  T R   
Sbjct: 156 SQETYRNYF 164
>ref|NP_060203.1| (NM_017733) hypothetical protein FLJ20265 [Homo sapiens]
 dbj|BAA91046.1| (AK000272) unnamed protein product [Homo sapiens]
 gb|AAH01249.1|AAH01249 (BC001249) hypothetical protein FLJ20265 [Homo sapiens]
          Length = 604

 Score =  247 bits (626), Expect = 5e-64
 Identities = 82/306 (26%), Positives = 135/306 (43%), Gaps = 25/306 (8%)

Query: 568 QAIRSTVVIFSMLLLWARLHRHSQLPQSLASGAALFMVYCFRGLNGQVLFFDVP-SHMAA 626
           +A  S +   S+L+++  + R        A    L  VYC+R   G V F   P S   +
Sbjct: 315 KAELSVLAALSLLVVFVLVQRGCSPVSKAALALGLLGVYCYRAAIGSVRFPWRPDSKDIS 374

Query: 627 KLMVPTLVIFWCCLALVLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQ 686
           K ++    ++   L  +L  G +  L               L  + + L   +LLAALL 
Sbjct: 375 KGIIEARFVYVFVLG-ILFTGTKDLLKSQVIAADFKLKTVGLWEIYSGL---VLLAALLF 430

Query: 687 RVHNILLLPVLLVALQQTYKLCDVYGTSARKFSVRLVHVYKIIMTIFLARMFFFYQGNSN 746
           R HN   LPVL  +L     +        R  +  +      +M  +  + FF++QGNSN
Sbjct: 431 RPHN---LPVLAFSLLIQTLMTKFIWKPLRHDAAEIT-----VMHYWFGQAFFYFQGNSN 482

Query: 747 SLSTIDLTPGYIGQTNYNPSIVAIFVTLNTYSADIHAFLYLVVHTLRSDLRSVGIMQLHP 806
           +++T+D++ G++G   Y      +     TY+  +    + +VH L S+ RS        
Sbjct: 483 NIATVDISAGFVGLDTYVEIPAVLLTAFGTYAGPVLWASH-LVHFLSSETRSG------- 534

Query: 807 PYSIAADSLIAPLYAALIMLPAAFYLCLLVGFRYHLFIYSVFSPKVLYDCYTVLVFYLVF 866
               +A S     YA +  +P   Y+ L+   RYHLFI+SVFSPK+LY+   +L+   V 
Sbjct: 535 ----SALSHACFCYALICSIPVFTYIVLVTSLRYHLFIWSVFSPKLLYEGMHLLITAAVC 590

Query: 867 LVTSLY 872
           +  +  
Sbjct: 591 VFFTAM 596
 Score = 85.9 bits (211), Expect = 3e-15
 Identities = 34/129 (26%), Positives = 52/129 (39%), Gaps = 18/129 (13%)

Query: 411 LSVIAAVVLNYTSHALDIIMTSSTLYSILLLVPISIAVYLTIDV-AQALLKIALPPLYTR 469
           L     +++    H +      S+ Y       +S      + V A ALL + +  L   
Sbjct: 95  LLFYLVILVLSAVHVIVCTSAESSCY----FCGLSWLAAGGVMVLASALLCVIVSVLTNV 150

Query: 470 RLKISIP-------------LPLPLLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLT 516
            +  + P             L L +L   A   L+LG+SSF+E E+ TWY+L NTL L  
Sbjct: 151 LVGGNTPRKNPMHPSSRWSELDLLILLGTAGHVLSLGASSFVEEEHQTWYFLVNTLCLAL 210

Query: 517 AFRTLRWRI 525
           +  T R   
Sbjct: 211 SQETYRNYF 219
>ref|NP_105837.1| (NC_002678) hypothetical protein [Mesorhizobium loti]
 dbj|BAB51623.1| (AP003005) hypothetical protein [Mesorhizobium loti]
          Length = 298

 Score =  240 bits (608), Expect = 8e-62
 Identities = 53/275 (19%), Positives = 87/275 (31%), Gaps = 23/275 (8%)

Query: 63  YDSFVLLLVDALRDDFPDA--TSMPVAYSR-ACEKLKLHVDIPTVTMPRLKSITTGTLSN 119
               +L+++D +          ++            K+   +P+ +     SI TG    
Sbjct: 23  KSKLLLIILDGVPYRNWRRLMGNLEGWVQSGEARVWKMRSVLPSTSACCYASIHTGVSPQ 82

Query: 120 FIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLF---PSEFTRQ--------- 167
              I  N       Q      + +            W + F   P +             
Sbjct: 83  VHGILSNENRFRVGQPDIFSEVSKAGGKTGAVTHSYWSEFFRSYPFDLVEDMEYDEPGGP 142

Query: 168 -----VENHDSFYV-NDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNASP 221
                      +   N     D ++  TL    +R      ILH   LD +GH  GN   
Sbjct: 143 ITHGRFHTMTGYNARNQMTPSDVDLFATLTMLTKRHGIDYGILHTCTLDSMGHRFGNDCH 202

Query: 222 RVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNNC 281
            +   +  MD ++   L         +M+T DHG  D G HGG+   + +    LYY   
Sbjct: 203 EMDHAVYAMDGMLAAFLPGWIAAGYEVMVTADHGQTDRGHHGGH--DDEMQDFALYYFGQ 260

Query: 282 SKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCL 316
            + P      +Q+ LAPT+   L V +P       
Sbjct: 261 GQGPETDTLLDQLQLAPTVLSRLGVPVPATMKAKP 295
>ref|NP_251941.1| (NC_002516) hypothetical protein [Pseudomonas aeruginosa]
 pir||E83240 hypothetical protein PA3251 [imported] - Pseudomonas aeruginosa
           (strain PAO1)
 gb|AAG06639.1|AE004747_12 (AE004747) hypothetical protein [Pseudomonas aeruginosa]
          Length = 269

 Score =  216 bits (545), Expect = 2e-54
 Identities = 60/256 (23%), Positives = 101/256 (39%), Gaps = 21/256 (8%)

Query: 66  FVLLLVDALRDDFPDATSMPVAYSRAC-----EKLKLHVDIPTVTMPRLKSITTGTLSNF 120
            +L+L+D L  +   A          C     +  +L  ++P+++ P  + I TG     
Sbjct: 5   VILVLLDGL--NHSVARDCMGHLQALCGAGRGQSYRLECELPSLSRPLYECILTGVPPID 62

Query: 121 IDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLF---PSEFTRQVENHDS---- 173
             I  N       + S  H  +      + A  H   +L+   P +  R     DS    
Sbjct: 63  SGILHNDVVRLSQEQSLFHYARAAGLSTAAAAYHWVSELYNRAPFDPARDRHTDDSALPI 122

Query: 174 ----FYVNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKE 229
               FY +D Y  D ++    E+   R   + +++H + +D  GH  G ASP      + 
Sbjct: 123 QRGHFYWSDHYP-DSHLFADAESLRRRHAPNFMLVHSMNIDDAGHRHGLASPAYRNAARR 181

Query: 230 MDEVVKKILDHKSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNNCSKTPSASK 289
            D ++ + L         + +T DHGM +   HGG    E  VPL+++ +  S+   A  
Sbjct: 182 ADALLSEYLHQWLAAGYQVAITADHGMNEDRSHGGILEEEREVPLFVFGDAFSRDDLAQP 241

Query: 290 RYNQIDLAPTLSVLLS 305
              Q DL  TL  +L 
Sbjct: 242 L--QTDLCGTLCEILG 255
>ref|NP_281901.1| (NC_002163) hypothetical protein Cj0729 [Campylobacter jejuni]
 pir||D81344 hypothetical protein Cj0729 [imported] - Campylobacter jejuni
           (strain NCTC 11168)
 emb|CAB73003.1| (AL139076) hypothetical protein Cj0729 [Campylobacter jejuni]
          Length = 269

 Score =  214 bits (542), Expect = 4e-54
 Identities = 55/261 (21%), Positives = 107/261 (40%), Gaps = 25/261 (9%)

Query: 63  YDSFVLLLVDALRDDFPDATSMPVAYSRA------CEKLKLHVDIPTVTMPRLKSITTGT 116
               +L+++D L      + S+ + Y  A       +   L  ++P+++ P  + + TG 
Sbjct: 2   MSKAILVVLDGL---NCKSASINMGYLNALCKENLGKFYSLECELPSMSRPLYECLLTGV 58

Query: 117 LSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKL-----FPSEFTRQVENH 171
                 I  N   +   Q S     K+Q      A  H   +L     F     R +E+ 
Sbjct: 59  KPVLSGIINN-KLSFSKQTSIFDLCKEQGLKAGGAAYHWVFELYNKKEFIPSLHRHIEDE 117

Query: 172 D------SFYVNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNASPRVPL 225
           +       FY  D Y  D ++    E    + +    ++H + +D  GH  G+ S     
Sbjct: 118 NLTLPYGHFYYEDDY-LDSHLFADGEHLRNKYNLDFTLIHSMNIDDAGHKFGSHSIEYAN 176

Query: 226 KLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNNCSKTP 285
           K K++D ++ + L       + +++T DHGM +G  HGG +  E LVP + + +  S   
Sbjct: 177 KTKKVDILISEYLPTWLEQGINVIITSDHGMTEGKSHGGLSEDEILVPFFTFGSAFSY-- 234

Query: 286 SASKRYNQIDLAPTLSVLLSV 306
             + +  Q ++  ++  +L +
Sbjct: 235 -ENAKIKQDEICGSICEILGL 254
>pdb|1EJJ|A Chain A, Crystal Structural Analysis Of Phosphoglycerate Mutase
           Cocrystallized With 3-Phosphoglycerate
 pdb|1EQJ|A Chain A, Crystal Structure Of Phosphoglycerate Mutase From Bacillus
           Stearothermophilus Complexed With 2-Phosphoglycerate
          Length = 511

 Score =  204 bits (516), Expect = 4e-51
 Identities = 41/178 (23%), Positives = 64/178 (35%), Gaps = 11/178 (6%)

Query: 141 LKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWS 200
                R   F G+   +   P   T  ++   S Y          VT  L  E+E   + 
Sbjct: 343 FMSGGREEEFPGEDRILINSPKVPTYDLKPEMSAY---------EVTDALLKEIEADKYD 393

Query: 201 LLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGG 260
            +IL+Y   D +GH  G   P +   ++ +DE + K++D       + ++T DHG AD  
Sbjct: 394 AIILNYANPDMVGH-SGKLEPTI-KAVEAVDECLGKVVDAILAKGGIAIITADHGNADEV 451

Query: 261 GHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIP 318
                 P        +      K           DLAPT+  LL +  P    G  + 
Sbjct: 452 LTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLI 509
>pir||T46865 phosphoglycerate mutase (EC 5.4.2.1), 2,
           3-diphosphoglycerate-independent [validated] - Bacillus
           stearothermophilus
 gb|AAD26328.1|AF120091_1 (AF120091) 2,3-bisphosphoglycerate-independent phosphoglycerate
           mutase [Geobacillus stearothermophilus]
          Length = 511

 Score =  203 bits (512), Expect = 1e-50
 Identities = 41/178 (23%), Positives = 64/178 (35%), Gaps = 11/178 (6%)

Query: 141 LKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWS 200
                R   F G+   +   P   T  ++   S Y          VT  L  E+E   + 
Sbjct: 343 FMSGGREEKFPGEDRILINSPKVPTYDLKPEMSAY---------EVTDALLKEIEADKYD 393

Query: 201 LLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGG 260
            +IL+Y   D +GH  G   P +   ++ +DE + K++D       + ++T DHG AD  
Sbjct: 394 AIILNYANPDMVGH-SGKLEPTI-KAVEAVDECLGKVVDAILAKGGIAIITADHGNADEV 451

Query: 261 GHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIP 318
                 P        +      K           DLAPT+  LL +  P    G  + 
Sbjct: 452 LTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLI 509
>ref|NP_458223.1| (NC_003198) 2,3-bisphosphoglycerate-independent phosphoglycerate
           mutase [Salmonella enterica subsp. enterica serovar
           Typhi]
 emb|CAD03290.1| (AL627280) 2,3-bisphosphoglycerate-independent phosphoglycerate
           mutase [Salmonella enterica subsp. enterica serovar
           Typhi]
          Length = 507

 Score =  203 bits (512), Expect = 1e-50
 Identities = 39/180 (21%), Positives = 69/180 (37%), Gaps = 15/180 (8%)

Query: 141 LKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWS 200
                    FAG+   +   P   T  ++   S            +T+ L   +E   + 
Sbjct: 336 FFNGGVEEPFAGEERILINSPKVATYDLQPEMSS---------AELTEKLVAAIESGKYD 386

Query: 201 LLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGG 260
            +I +Y   D +GH  G     +   ++ +D  ++++          L++T DHG A+  
Sbjct: 387 TIICNYPNGDMVGHT-GVMEAAI-KAVEALDNCIEQVTKAVESVGGQLLITADHGNAEQM 444

Query: 261 ---GHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLI 317
                G    A T +P+ L Y    K   A +     D+APT+  L+ +EIP    G  +
Sbjct: 445 RDPATGQEHTAHTNLPVPLIYVG-EKNVKAVEGGKLSDIAPTMLSLMGMEIPQEMTGKPL 503
>ref|NP_462604.1| (NC_003197) phosphoglyceromutase [Salmonella typhimurium LT2]
 gb|AAL22563.1| (AE008872) phosphoglyceromutase [Salmonella typhimurium LT2]
          Length = 514

 Score =  202 bits (511), Expect = 2e-50
 Identities = 39/180 (21%), Positives = 69/180 (37%), Gaps = 15/180 (8%)

Query: 141 LKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWS 200
                    FAG+   +   P   T  ++   S            +T+ L   +E   + 
Sbjct: 343 FFNGGVEEPFAGEERILINSPKVATYDLQPEMSS---------AELTEKLVAAIESGKYD 393

Query: 201 LLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGG 260
            +I +Y   D +GH  G     +   ++ +D  ++++          L++T DHG A+  
Sbjct: 394 TIICNYPNGDMVGHT-GVMEAAI-KAVEALDNCIEQVTKAVESVGGQLLITADHGNAEQM 451

Query: 261 ---GHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLI 317
                G    A T +P+ L Y    K   A +     D+APT+  L+ +EIP    G  +
Sbjct: 452 RDPATGQAHTAHTNLPVPLIYVG-EKNVKAVEGGKLSDIAPTMLSLMGMEIPQEMTGKPL 510
>ref|NP_465979.1| (NC_003210) highly similar to phosphoglycerate mutase [Listeria
           monocytogenes EGD-e]
 emb|CAD00534.1| (AL591983) highly similar to phosphoglycerate mutase [Listeria
           monocytogenes]
          Length = 510

 Score =  201 bits (507), Expect = 5e-50
 Identities = 34/179 (18%), Positives = 67/179 (36%), Gaps = 11/179 (6%)

Query: 141 LKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWS 200
                R   F G++  +   P   T  ++   S Y          VT  L  +++     
Sbjct: 342 FMNGGRNEEFPGENRILINSPKVETYDLQPEMSAY---------EVTDALVEDIKNDKHD 392

Query: 201 LLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGG 260
            +IL++   D +GH  G   P +   ++ +DE + +++D         ++  DHG ++  
Sbjct: 393 AIILNFANPDMVGH-SGMLEPTI-KAIEAVDENLGRVVDLILEKGGSAIIFADHGNSETM 450

Query: 261 GHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPE 319
                 P      + +      K  +  +     D+APT+  LL V+ P    G  + +
Sbjct: 451 STPEGKPHTAHTTVPVPVIVTKKGVTLREGGRLADVAPTMLDLLGVKKPAEMTGESLIQ 509
>ref|NP_471880.1| (NC_003212) highly similar to phosphoglycerate mutase [Listeria
           innocua]
 emb|CAC97777.1| (AL596172) highly similar to phosphoglycerate mutase [Listeria
           innocua]
          Length = 510

 Score =  200 bits (505), Expect = 8e-50
 Identities = 34/179 (18%), Positives = 67/179 (36%), Gaps = 11/179 (6%)

Query: 141 LKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWS 200
                R   F G++  +   P   T  ++   S Y          VT  L  +++     
Sbjct: 342 FMNGGRNEEFPGENRILINSPKVETYDLKPEMSAY---------EVTDALVEDIKNDKHD 392

Query: 201 LLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGG 260
            +IL++   D +GH  G   P +   ++ +DE + +++D         ++  DHG ++  
Sbjct: 393 AIILNFANPDMVGH-SGMLEPTI-KAIEAVDENLGRVVDLILEKGGSAIIFADHGNSETM 450

Query: 261 GHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPE 319
                 P      + +      K  +  +     D+APT+  LL V+ P    G  + +
Sbjct: 451 STPEGKPHTAHTTVPVPVIVTKKGVTLREGGRLADVAPTMLDLLGVKKPAEMTGESLIQ 509
>ref|NP_418069.1| (NC_000913) putative 2,3-bisphosphoglycerate-independent
           phosphoglycerate mutase [Escherichia coli K12]
 sp|P37689|PMGI_ECOLI 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
           (Phosphoglyceromutase) (BPG-independent PGAM)
 pir||S47833 probable phosphoglycerate mutase (EC 5.4.2.1), 2,
           3-diphosphoglycerate-independent - Escherichia coli
 gb|AAB18589.1| (U00039) No definition line found [Escherichia coli]
 gb|AAC76636.1| (AE000439) putative 2,3-bisphosphoglycerate-independent
           phosphoglycerate mutase [Escherichia coli K12]
          Length = 514

 Score =  198 bits (501), Expect = 3e-49
 Identities = 40/180 (22%), Positives = 69/180 (38%), Gaps = 15/180 (8%)

Query: 141 LKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWS 200
                   SF G+   +   P   T  ++   S            +T+ L   ++   + 
Sbjct: 343 FFNGGVEESFKGEDRILINSPKVATYDLQPEMSS---------AELTEKLVAAIKSGKYD 393

Query: 201 LLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGG 260
            +I +Y   D +GH  G     V   ++ +D  V+++          L++T DHG A+  
Sbjct: 394 TIICNYPNGDMVGHT-GVMEAAV-KAVEALDHCVEEVAKAVESVGGQLLITADHGNAEQM 451

Query: 261 ---GHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLI 317
                G    A T +P+ L Y    K   A +     D+APT+  L+ +EIP    G  +
Sbjct: 452 RDPATGQAHTAHTNLPVPLIYVGD-KNVKAVEGGKLSDIAPTMLSLMGMEIPQEMTGKPL 510
>ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo sapiens]
 gb|AAH13987.1|AAH13987 (BC013987) Similar to hypothetical protein MGC3079 [Homo sapiens]
          Length = 454

 Score =  198 bits (499), Expect = 4e-49
 Identities = 54/227 (23%), Positives = 97/227 (41%), Gaps = 32/227 (14%)

Query: 194 LERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGD 253
           ++  +W +LI H+LG+DH GH  G   P +  KL +MD+V++ +++     + LL++ GD
Sbjct: 1   MDSGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLE-NDTLLVVAGD 59

Query: 254 HGMADGGGHGGNTPAETLVPLYLYYNNC---SKTPSASKRYNQIDLAPTLSVLLSVEIPT 310
           HGM   G HGG++  E    L+LY       S  P   +   Q+ L PTL++LL + IP 
Sbjct: 60  HGMTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPF 119

Query: 311 LSIGCLIPEMLQSLSLEH-------QLYAYFYNAHHL------------------LNKAR 345
            +IG ++ E+               Q  A   NA  +                  L++ +
Sbjct: 120 GNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQ 179

Query: 346 VKFGHEIVHRSDYYTWYQNATLLHKKLLRPLREGDGGGASQ-VYYQN 391
             F              + A      ++  L++      ++ +  ++
Sbjct: 180 NLFSKASADYQWLLQSPKGAEATLPTVIAELQQF--LRGARAMCIES 224
 Score =  168 bits (422), Expect = 5e-40
 Identities = 27/189 (14%), Positives = 58/189 (30%), Gaps = 33/189 (17%)

Query: 718 FSVRLVHVYKIIM-TIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIV---AIFVT 773
                   ++ +     +A   F+  G+      I     ++G    + S     A+ V 
Sbjct: 246 TPGPFTVPWQAVSAWALMATQTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVG 305

Query: 774 LNTYSADIHAFLYLVVHTLRS---DLRSVGIMQLHPPYSI-------------------- 810
            NT+++ +   +   +  L     + + +   Q  P                        
Sbjct: 306 ANTFASHLLFAVGCPLLLLWPFLCESQGLRKRQQPPGNEADARVRPEEEEEPLMEMRLRD 365

Query: 811 ----AADSLIAPLYAALIMLPAAFYLCLL--VGFRYHLFIYSVFSPKVLYDCYTVLVFYL 864
                  +L+      L +L      C L     R HL ++ VF+PK +++    +V  +
Sbjct: 366 APQHFYAALLQLGLKYLFILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSSV 425

Query: 865 VFLVTSLYF 873
             L+     
Sbjct: 426 GLLLGIALV 434
>ref|NP_290195.1| (NC_002655) putative 2,3-bisphosphoglycerate-independent
           phosphoglycerate mutase [Escherichia coli O157:H7
           EDL933]
 ref|NP_312517.1| (NC_002695) putative 2,3-bisphosphoglycerate-independent
           phosphoglycerate mutase [Escherichia coli O157:H7]
 gb|AAG58759.1|AE005588_10 (AE005588) putative 2,3-bisphosphoglycerate-independent
           phosphoglycerate mutase [Escherichia coli O157:H7
           EDL933]
 dbj|BAB37913.1| (AP002566) putative 2,3-bisphosphoglycerate-independent
           phosphoglycerate mutase [Escherichia coli O157:H7]
          Length = 514

 Score =  196 bits (495), Expect = 1e-48
 Identities = 40/180 (22%), Positives = 68/180 (37%), Gaps = 15/180 (8%)

Query: 141 LKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWS 200
                   SF G+   +   P   T  ++   S            +T+ L   ++   + 
Sbjct: 343 FFNGGVEESFKGEDRILINSPKVATYDLQPEMSS---------AELTEKLVAAIKSGKYD 393

Query: 201 LLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGG 260
            +I +Y   D +GH  G     V   ++ +D  V+++          L++T DHG A+  
Sbjct: 394 TIICNYPNGDMVGHT-GVMEAAV-KAVEALDHCVEEVAKAVESVGGQLLITADHGNAEQM 451

Query: 261 ---GHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLI 317
                G    A T +P+ L Y    K   A       D+APT+  L+ +EIP    G  +
Sbjct: 452 RDPATGQAHTAHTNLPVPLIYVGD-KNVKAVAGGKLSDIAPTMLSLMGMEIPQEMTGKPL 510
>ref|NP_244424.1| (NC_002570) 2,3-bisphosphoglycerate-independent phosphoglycerate
           mutase [Bacillus halodurans]
 dbj|BAB07276.1| (AP001519) 2,3-bisphosphoglycerate-independent phosphoglycerate
           mutase [Bacillus halodurans]
          Length = 510

 Score =  195 bits (492), Expect = 3e-48
 Identities = 38/178 (21%), Positives = 65/178 (36%), Gaps = 11/178 (6%)

Query: 141 LKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWS 200
                R   F G+   +   P   T  ++   S Y          VT  L  E+E     
Sbjct: 343 FFSGGREEPFPGEERILIDSPKVATYDLKPEMSAY---------EVTDALLNEIEADKHD 393

Query: 201 LLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGG 260
           ++IL++   D +GH  G   P +   ++ +DE + K++D         ++T DHG AD  
Sbjct: 394 VIILNFANPDMVGH-SGMLEPTI-KAVEAVDECLGKVVDAILAKGGAAVITADHGNADEV 451

Query: 261 GHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIP 318
                 P        +      +  +  +     DL+PT+  LL  + P    G  + 
Sbjct: 452 VTLEGKPMTAHTTNKVPVIVTEEGLNLREDGILADLSPTVLDLLGGKQPAEMTGKTLI 509
>ref|NP_391271.1| (NC_000964) phosphoglycerate mutase [Bacillus subtilis]
 sp|P39773|PMGI_BACSU 2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE
           (PHOSPHOGLYCEROMUTASE) (BPG-INDEPENDENT PGAM)
           (VEGETATIVE PROTEIN 107) (VEG107)
 pir||D69675 phosphoglycerate mutase (EC 5.4.2.1), 2,
           3-diphosphoglycerate-independent [validated] - Bacillus
           subtilis
 emb|CAB15396.1| (Z99121) phosphoglycerate mutase [Bacillus subtilis]
          Length = 511

 Score =  194 bits (491), Expect = 4e-48
 Identities = 40/179 (22%), Positives = 65/179 (35%), Gaps = 11/179 (6%)

Query: 141 LKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWS 200
                R   F G+   +   P   T  ++   S Y          V   L  E+E     
Sbjct: 343 FMSGGREAEFPGEERILINSPKVATYDLKPEMSAY---------EVKDALVKEIEADKHD 393

Query: 201 LLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGG 260
            +IL++   D +GH  G   P +   ++ +DE + +++D         ++T DHG AD  
Sbjct: 394 AIILNFANPDMVGH-SGMVEPTI-KAIEAVDECLGEVVDAILAKGGHAIITADHGNADIL 451

Query: 261 GHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPE 319
                 P        +      +  +  +     DLAPTL  LL VE P    G  + +
Sbjct: 452 ITESGEPHTAHTTNPVPVIVTKEGITLREGGILGDLAPTLLDLLGVEKPKEMTGTSLIQ 510
>ref|NP_403728.1| (NC_003143) 2,3-bisphosphoglycerate-independent phosphoglycerate
           mutase [Yersinia pestis]
 emb|CAC88930.1| (AJ414141) 2,3-bisphosphoglycerate-independent phosphoglycerate
           mutase [Yersinia pestis]
          Length = 515

 Score =  193 bits (488), Expect = 1e-47
 Identities = 36/180 (20%), Positives = 70/180 (38%), Gaps = 15/180 (8%)

Query: 141 LKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWS 200
                    F G+   +   P   T  ++   S            +T+ L + +    + 
Sbjct: 344 FYNGGVEEPFKGEDRILINSPKVATYDLQPEMSS---------AELTEKLVSAIGSGKYD 394

Query: 201 LLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGG 260
           ++I +Y   D +GH     +      ++ +D  +++++      +  L++T DHG A+  
Sbjct: 395 VIICNYPNGDMVGHTGDYDAA--VKAVETLDNCIEQVVAAVKAADGQLLITADHGNAEQM 452

Query: 261 ---GHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLI 317
                G    A T +P+ L Y    K   A +     D+APT+  L+ +EIP    G  +
Sbjct: 453 RDPATGQAHTAHTSLPVPLIYVGN-KAVKAVEGGKLSDIAPTMLSLMEMEIPQEMTGKPL 511
>ref|NP_371299.1| (NC_002758) 2, 3-diphosphoglycerate-independent phosphoglycerate
           mutase [Staphylococcus aureus subsp. aureus Mu50]
 ref|NP_373985.1| (NC_002745) 2, 3-diphosphoglycerate-independentphosphoglycer ate
           mutase [Staphylococcus aureus subsp. aureus N315]
 dbj|BAB41963.1| (AP003131) 2, 3-diphosphoglycerate-independentphosphoglycer ate
           mutase [Staphylococcus aureus subsp. aureus N315]
 dbj|BAB56937.1| (AP003360) 2, 3-diphosphoglycerate-independent phosphoglycerate
           mutase [Staphylococcus aureus subsp. aureus Mu50]
          Length = 505

 Score =  192 bits (484), Expect = 3e-47
 Identities = 42/179 (23%), Positives = 70/179 (38%), Gaps = 11/179 (6%)

Query: 140 RLKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDW 199
                 R   F G+   +   P   T  ++   S Y          V   L  EL + D 
Sbjct: 336 YFMSGGRNEEFKGERRRLIDSPKVATYDLKPEMSAY---------EVKDALLEELNKGDL 386

Query: 200 SLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADG 259
            L+IL++   D +GH  G   P +   ++ +DE + +++D     +   ++T DHG +D 
Sbjct: 387 DLIILNFANPDMVGH-SGMLEPTI-KAIEAVDECLGEVVDKILDMDGYAIITADHGNSDQ 444

Query: 260 GGHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIP 318
                + P  T     +      +  +  +     DLAPTL  LL+VE P    G  + 
Sbjct: 445 VLTDDDQPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVEQPEDMTGESLI 503
>ref|NP_116023.1| (NM_032634) hypothetical protein MGC3079 [Homo sapiens]
 gb|AAH01030.1|AAH01030 (BC001030) Similar to phosphatidylinositol glycan, class O [Homo
           sapiens]
          Length = 454

 Score =  189 bits (476), Expect = 2e-46
 Identities = 52/227 (22%), Positives = 94/227 (40%), Gaps = 32/227 (14%)

Query: 194 LERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGD 253
           ++  +W +   H LG+DH GH  G   P +  KL +MD+V++ +++     + LL++ GD
Sbjct: 1   MDSGEWEVSNQHVLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLE-NDTLLVVAGD 59

Query: 254 HGMADGGGHGGNTPAETLVPLYLYYNNC---SKTPSASKRYNQIDLAPTLSVLLSVEIPT 310
           HGM   G HGG++  E    L+LY       S  P   +   Q+ L PTL++LL + IP 
Sbjct: 60  HGMTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPF 119

Query: 311 LSIGCLIPEMLQSLSLEH-------QLYAYFYNAHHL------------------LNKAR 345
            +IG ++ E+               Q  A   NA  +                  L++ +
Sbjct: 120 GNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQ 179

Query: 346 VKFGHEIVHRSDYYTWYQNATLLHKKLLRPLREGDGGGASQ-VYYQN 391
             F              + A      ++  L++      ++ +  ++
Sbjct: 180 NLFSKASADYQWLLQSPKGAEATLPTVIAELQQF--LRGARAMCIES 224
 Score =  169 bits (425), Expect = 2e-40
 Identities = 27/189 (14%), Positives = 58/189 (30%), Gaps = 33/189 (17%)

Query: 718 FSVRLVHVYKIIM-TIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIV---AIFVT 773
                   ++ +     +A   F+  G+      I     ++G    + S     A+ V 
Sbjct: 246 TPGPFTVPWQAVSAWALMATQTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVG 305

Query: 774 LNTYSADIHAFLYLVVHTLRS---DLRSVGIMQLHPPYSI-------------------- 810
            NT+++ +   +   +  L     + + +   Q  P                        
Sbjct: 306 ANTFASHLLFAVGCPLLLLWPFLCESQGLRKRQQPPGNEADARVRPEEEEEPLMEMRLRD 365

Query: 811 ----AADSLIAPLYAALIMLPAAFYLCLL--VGFRYHLFIYSVFSPKVLYDCYTVLVFYL 864
                  +L+      L +L      C L     R HL ++ VF+PK +++    +V  +
Sbjct: 366 APQHFYAALLQLGLKYLFILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSSV 425

Query: 865 VFLVTSLYF 873
             L+     
Sbjct: 426 GLLLGIALV 434
>pir||I40024 phosphoglycerate mutase - Bacillus subtilis
 gb|AAA21680.1| (L29475) phosphoglycerate mutase [Bacillus subtilis]
          Length = 511

 Score =  189 bits (476), Expect = 2e-46
 Identities = 39/179 (21%), Positives = 64/179 (34%), Gaps = 11/179 (6%)

Query: 141 LKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWS 200
                R   F G+   +   P   T  ++   S Y          V   L  E+E     
Sbjct: 343 FMSGGREAEFPGEERILINSPKVATYDLKPEMSAY---------EVKDALVKEIEADKHD 393

Query: 201 LLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGG 260
            +IL++   D +GH  G   P +   ++ +DE + +++D         ++T D G AD  
Sbjct: 394 AIILNFANPDMVGH-SGMVEPTI-KAIEAVDECLGEVVDAMVAKGGHAIITADDGNADIL 451

Query: 261 GHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPE 319
                 P        +      +  +  +     DLAPTL  LL VE P    G  + +
Sbjct: 452 ITESGEPHTAHTTNPVPVIVTKEGITLREGGILGDLAPTLLDLLGVEKPKEMTGTSLIQ 510
>ref|NP_229990.1| (NC_002505) phosphoglycerate mutase,
           2,3-bisphosphoglycerate-independent [Vibrio cholerae]
 pir||G82335 phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent VC0336
           [imported] - Vibrio cholerae (group O1 strain N16961)
 gb|AAF93509.1| (AE004122) phosphoglycerate mutase,
           2,3-bisphosphoglycerate-independent [Vibrio cholerae]
          Length = 510

 Score =  186 bits (468), Expect = 2e-45
 Identities = 40/180 (22%), Positives = 71/180 (39%), Gaps = 15/180 (8%)

Query: 141 LKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWS 200
                    F G+   +   P   T  ++   S          + +T  L   ++   + 
Sbjct: 341 FFNGGVENEFPGEERQLVASPKVATYDLQPEMSS---------KELTDKLVAAIKSGKYD 391

Query: 201 LLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHKSFPNVLLMLTGDHGMADGG 260
            +I +Y   D +GH  G     V    + +DE + ++++     +  L++T DHG A+  
Sbjct: 392 AIICNYPNGDMVGHT-GVYEAAV-KACEAVDECIGRVVEAIKEVDGQLLITADHGNAEMM 449

Query: 261 ---GHGGNTPAETLVPLYLYYNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLI 317
                GG   A T +P+ L Y    K  S  +     DLAPT+  L  ++IP    G ++
Sbjct: 450 IDPETGGVHTAHTSLPVPLIYVGN-KAISLKEGGKLSDLAPTMLALSDLDIPADMSGQVL 508
>dbj|BAA87261.1| (AB027957) Hypothetical protein [Schizosaccharomyces pombe]
          Length = 179

 Score =  181 bits (456), Expect = 5e-44
 Identities = 37/178 (20%), Positives = 66/178 (36%), Gaps = 24/178 (13%)

Query: 198 DWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILDHK-----SFPNVLLMLTG 252
           D  +  LH LG+D IGH +   S      ++ +D  +++++D       +      + T 
Sbjct: 3   DKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTA 62

Query: 253 DHGMADGGGHGGNTPAETLVPLYLYYNNC-----SKTPSASK-------------RYNQI 294
           DHGM+D G HG      T  P+  +          K     +                Q 
Sbjct: 63  DHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQA 122

Query: 295 DLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLLNKARVKFGHEI 352
           D+A  +S L+ +  P  S+G +  + L   S   +      NA  +  +  +K   + 
Sbjct: 123 DIAALMSYLVGLNFPVNSVGQIPLDYLDC-SSRRKAEVALMNALEIGEQYNLKSASKD 179
CPU time:   269.21 user secs.	    3.35 sys. secs	  272.56 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.318    0.178    0.466 

Gapped
Lambda     K      H
   0.270   0.0623    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 590660462
Number of Sequences: 887402
Number of extensions: 33390439
Number of successful extensions: 181530
Number of sequences better than 10.0: 1526
Number of HSP's better than 10.0 without gapping: 173
Number of HSP's successfully gapped in prelim test: 1383
Number of HSP's that attempted gapping in prelim test: 178168
Number of HSP's gapped (non-prelim): 3625
length of query: 880
length of database: 277,845,442
effective HSP length: 56
effective length of query: 824
effective length of database: 228,150,930
effective search space: 187996366320
effective search space used: 187996366320
T: 11
A: 40
X1: 15 ( 6.9 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.8 bits)
S2: 78 (34.4 bits)