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GPI Anchor Biosynthesis Report: AN3715.1 (GAA1 family, Aspergillus nidulans)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query=
         (633 letters)

Database: nr
           1,543,518 sequences; 504,497,942 total letters

Searching..................................................

Converged !!!


Results of PSI-Blast iteration 4

Distribution of 30 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)

gb|EAA51928.1| hypothetical protein MG03523.4 [Magnaporthe grise... 714 0.0
ref|XP_235447.2| similar to glycosylphosphatidylinositol anchor ... 622 e-177
ref|NP_034461.1| GPI anchor attachment protein 1 [Mus musculus] ... 621 e-176
ref|NP_003792.1| anchor attachment protein 1; glycophosphatidyli... 611 e-173
ref|NP_572273.2| CG3033-PA [Drosophila melanogaster] >gi|7290645... 582 e-165
ref|XP_331144.1| hypothetical protein [Neurospora crassa] >gi|28... 579 e-164
ref|XP_311451.1| ENSANGP00000018454 [Anopheles gambiae] >gi|2129... 570 e-161
emb|CAD60753.1| unnamed protein product [Podospora anserina] 564 e-159
gb|AAK77275.1| GH05723p [Drosophila melanogaster] 541 e-152
gb|AAH06383.2| GPAA1 protein [Homo sapiens] 528 e-148
pir||T32771 hypothetical protein F33D11.9b - Caenorhabditis elegans 514 e-144
pir||T46923 hypothetical protein DKFZp434E1512.1 - human >gi|701... 498 e-139
ref|NP_491700.2| anchor attachment protein 1 (1G434) [Caenorhabd... 494 e-138
gb|AAH60413.1| Unknown (protein for MGC:68658) [Xenopus laevis] 452 e-125
ref|NP_593498.1| putative glycosylphosphatidylinositol anchor at... 405 e-111
ref|NP_916949.1| putative GPAA1 - like protein [Oryza sativa (ja... 355 3e-96
gb|EAA16082.1| hypothetical protein [Plasmodium yoelii yoelii] 335 2e-90
ref|NP_705572.1| hypothetical protein [Plasmodium falciparum 3D7... 330 5e-89
ref|NP_197414.2| GPAA1 - like protein [Arabidopsis thaliana] 311 3e-83
gb|AAO00773.1| GPAA1 - like protein [Arabidopsis thaliana] 311 3e-83
dbj|BAC81736.1| GPI transamidase component GAA1 [Trypanosoma bru... 278 3e-73
emb|CAB86709.1| hypothetical protein L3640.14 [Leishmania major] 265 2e-69
ref|XP_290985.3| similar to LIM and senescent cell antigen-like ... 245 3e-63
ref|NP_491701.1| gaa1-like, GPI transamidase component (1G434) [... 152 2e-35
Alignments
>gb|EAA51928.1| hypothetical protein MG03523.4 [Magnaporthe grisea 70-15]
          Length = 606

 Score =  714 bits (1824), Expect = 0.0
 Identities = 339/638 (53%), Positives = 424/638 (66%), Gaps = 55/638 (8%)

Query: 3   LKSSLRNLRNNPYFLFVRLPYLLSFLCIVSGVIWLFLLPLDDYSRKTYISENALLPGQVH 62
           L S++ +LR +P  L  +LP  LS LCIV G++ L LLPLD+++R+TYISENALLPGQVH
Sbjct: 4   LLSTVLSLRRDPRIL--KLPPYLSVLCIVVGIVSLLLLPLDNFTRRTYISENALLPGQVH 61

Query: 63  AYFAGSEQNVFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQSILMASGLKVATQG 122
            YFAGS+QNVFR YK E+  L+D    +            I++K++SI    GLKV  Q 
Sbjct: 62  TYFAGSDQNVFRAYKHEVNSLVDKSNVE------------INDKLESIFKGVGLKVGRQN 109

Query: 123 YEYKSSGITHQGENIYAIIQAPRGDATEAIVLVAAWKTIDGQLNLNGVSLALTLARYFKR 182
           + Y SSGI H GEN+YAI+QAPRGDATEAIVLV AW+  +G+LN NGV+LALTLARYF+R
Sbjct: 110 FTYSSSGIQHSGENVYAILQAPRGDATEAIVLVTAWRNPNGELNRNGVALALTLARYFRR 169

Query: 183 WSLWSKDIIFVFPPDSKSGTQAWVDAYHDMQPPT-VQPLPLKSGALQGGLAIEYPFDHRF 241
           WSLWSKDIIF+ PPDS +G QAWVDAYHD   P  V  LPLKSGALQG LA++Y  + R+
Sbjct: 170 WSLWSKDIIFLLPPDSLAGPQAWVDAYHDAHDPRKVAALPLKSGALQGALALDYTREDRY 229

Query: 242 ENLHIIYDGVNGQLPNLDLFNTAVSIAGGQMGIGTRLQEMWDHNGSYEKRLQTMLRGMVK 301
           E++H++YDGVNGQLPNLDLFN+ V +AGGQMGIG  +Q+MW H   Y  RLQTMLRGM++
Sbjct: 230 ESVHLVYDGVNGQLPNLDLFNSLVHVAGGQMGIGVSIQDMWHHRNDYRDRLQTMLRGMLR 289

Query: 302 QGLGYAAGAHSSFMPYHIDAITLQTQGNGWQDEMALGRTVESLCRSLNNLLEHLHQSFFF 361
           QG+G   GAHS FMPYH+DA+TL   G+GWQDEMALGR VE   RSLNNLLEHLHQSFFF
Sbjct: 290 QGIGAGTGAHSCFMPYHVDAVTLVPYGDGWQDEMALGRVVEGTFRSLNNLLEHLHQSFFF 349

Query: 362 YLLMQTHRFVSIGTYLPSAMLIAGNFTIMAIALWLRTGYYKDSTQAATVSARLVRDENIT 421
           YLLM    FVSIGTYLPSAML+  NFTIM+I +W ++G  ++  +     A      ++T
Sbjct: 350 YLLMHKEHFVSIGTYLPSAMLLGANFTIMSILMWFKSGQPEEEEEPEGQEAATNSGASVT 409

Query: 422 TSESEKAQLASKDRNETAPTTGNPATKAAERQLALPLTLIIGLHLIGLIPLYIFNNISHD 481
           +                            ER+L +PL++I     +G +PLY+FN++   
Sbjct: 410 SES----------------------RPVVERELLVPLSVIGTCLFLGAVPLYMFNHLPAG 447

Query: 482 KYTLATYTSIAINAILPICLSFILSRITTPTQISHQLHLIKSLSLLPLGLFLSTLATLNF 541
               +     AIN  LP   S +L  +  PT  + Q  LIK   LL LG+F+S+LA LNF
Sbjct: 448 LLYPSFIAFSAINIFLPPIASQLLETLYWPT--TQQYQLIKCFYLLVLGMFISSLAILNF 505

Query: 542 SLSFMTGLLCTPLSFMHIFDAKTKPFVRYTLSAFGMAFLNVISPPVVLLVG--------- 592
           SL+F  GL+ TPL+F   F A   P +R+      +A LN+ SPP V  V          
Sbjct: 506 SLAFWIGLIATPLTFTRPFPA--SPALRWAY----VALLNIASPPAVFAVACAAWRLDVA 559

Query: 593 -FLTEAAFGWDVWGMWTQVVVWCVWWPAWVVGGVVLGG 629
             L  AAFGWDVWGM+T VVVWCVWWPAW+ G +V+ G
Sbjct: 560 EVLQAAAFGWDVWGMYTAVVVWCVWWPAWLAGSLVVLG 597
>ref|XP_235447.2| similar to glycosylphosphatidylinositol anchor attachment 1 (GPAA1)
           [Rattus norvegicus]
          Length = 619

 Score =  622 bits (1589), Expect = e-177
 Identities = 176/623 (28%), Positives = 278/623 (44%), Gaps = 82/623 (13%)

Query: 1   MALKSSLRNLRNNPYFLFVRLPYLLSFLCIVSGVIWLFLLPLDDYSRKTYISENALLPGQ 60
           M L S     R     + +RL   L  L  V+G+ W   L     +++TY+SENA+    
Sbjct: 1   MGLLSDPVRRRALAR-IVLRLNTPLCVLSYVAGIAWFLALAFPPLTQRTYMSENAMGSTM 59

Query: 61  VHAYFAGSEQNVFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQSILMASGLKVAT 120
           V   F G ++   R + ++                 ++   +    ++  + + GL+V T
Sbjct: 60  VEEQFVGGDR--ARNFARDF------------AAHRKKPGALPVAWLERAMRSVGLEVYT 105

Query: 121 QGYEYK--SSGITHQ-----GENIYAIIQAPRGDATEAIVLVAAWKTIDGQLNLNGVSLA 173
           Q +  K      TH+     G N+Y I++APR  +TE++VL           N   V L 
Sbjct: 106 QSFSRKLPFPDETHERYMVSGTNVYGILRAPRAASTESLVLTVPCGP--DTTNSQAVGLL 163

Query: 174 LTLARYFKRWSLWSKDIIFVFPPDSKSGTQAWVDAYHDMQPPTVQPLPL--KSGALQGGL 231
           L LA +F+    W+KDIIF+       GT+AW++AYHD+    +Q  PL  ++GA+Q  +
Sbjct: 164 LALAAHFRGQIYWAKDIIFLVTEHDLLGTEAWLEAYHDINVTGIQSSPLQGRAGAIQAAV 223

Query: 232 AIEYPFDHRFENLHIIYDGVNGQLPNLDLFNTAVSIA---GGQMGIGTRLQEMWDHNGSY 288
           A+E   D    +L +  +G+NGQLPNLDL N   +     G    +  + Q  W      
Sbjct: 224 ALELSSD-VVTSLDVTVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKPQ-DWTSLEGP 281

Query: 289 EKRLQTMLRGMVKQGLGYAAGAHSSFMPYHIDAITLQTQGNGWQ---DEMALGRTVESLC 345
            + LQT+L  +++Q  G   G H  F+ Y ++A+TL+   +  Q   D +A+G+ +E + 
Sbjct: 282 LQGLQTLLLMVLRQASGRPHGPHGLFLRYGVEALTLRGINSFRQYKYDLVAVGKALEGMF 341

Query: 346 RSLNNLLEHLHQSFFFYLLMQTHRFVSIGTYLPSAMLIAGNFTIMAIALWLRTGYYKDST 405
           R LN+LLE LHQSFFFYLL    RFVSIG Y+P+   +     + A+ LW++        
Sbjct: 342 RKLNHLLERLHQSFFFYLLPALSRFVSIGLYMPATGFLLLVLGLKALELWMQL------- 394

Query: 406 QAATVSARLVRDENITTSESEKAQLASKDRNETAPTTGNPATKAAERQLALPLTLIIGLH 465
                      +  +   E+ K           AP  G+P        LA  +  ++   
Sbjct: 395 ----------HEAGVNPEEAGK-----------APGPGSPPLATQSVSLASLMAPLLISQ 433

Query: 466 LIGLIPLYIF----NNISHDKYTLATYTSIAINAILPICLSFILSRITTPTQISHQ---- 517
            +GL  LY       +++   + +A   ++    +L I ++ +     T   +S Q    
Sbjct: 434 AMGL-ALYFLPVLGQHVAAQHFPVAEAEAVV-LTLLAIYVAGLALPHNTHRVVSSQVPDR 491

Query: 518 -LHLIKSLSLLPLGLFLSTLATLNFSLSFMTGLLCTPLSFMHIFDAKTKPFVRYTLSAFG 576
               +K ++L+ L L L  +A LNFSL F+      P +      A TKP    TL A  
Sbjct: 492 GWMALKLVALIYLALQLGCIALLNFSLGFLLAATMVPAA------ALTKPHGPRTLYA-- 543

Query: 577 MAFLNVISPPVVLLVGFLTEAAF 599
            A L V SP V L          
Sbjct: 544 -ALLVVTSPAVTLFGSLFLWREL 565
>ref|NP_034461.1| GPI anchor attachment protein 1 [Mus musculus]
 dbj|BAA82589.1| glycosylphosphatidylinositol anchor attachment 1 (GPAA1) [Mus
           musculus]
 dbj|BAA82591.1| glycosylphosphatidylinositol anchor attachment 1 (GPAA1) [Mus
           musculus]
 dbj|BAB03274.1| GPI anchor attachment protein [Mus musculus]
 dbj|BAB03275.1| GPI anchor attachment protein [Mus musculus]
 gb|AAH06697.1| GPI anchor attachment protein 1 [Mus musculus]
 dbj|BAC36840.1| unnamed protein product [Mus musculus]
          Length = 621

 Score =  621 bits (1586), Expect = e-176
 Identities = 174/625 (27%), Positives = 275/625 (43%), Gaps = 82/625 (13%)

Query: 1   MALKSSLRNLRNNPYFLFVRLPYLLSFLCIVSGVIWLFLLPLDDYSRKTYISENALLPGQ 60
           M L S     R     + +RL   L  L  V+G+ W   L     +++TY+SENA+    
Sbjct: 1   MGLLSDPVRRRALAR-IVLRLNTPLCVLSYVAGIAWFLALAFPPLTQRTYMSENAMGSTM 59

Query: 61  VHAYFAGSEQNVFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQSILMASGLKVAT 120
           V   F G ++   R + ++                 ++   +    ++  + + GL+V T
Sbjct: 60  VEEQFVGGDR--ARSFARDF------------AAHRKKPGALPVAWLERSMRSVGLEVYT 105

Query: 121 QGYEYK--SSGITHQ-----GENIYAIIQAPRGDATEAIVLVAAWKTIDGQLNLNGVSLA 173
           Q +  K      TH+     G N+Y I++APR  +TE++VL           N   V L 
Sbjct: 106 QSFSRKLPFPDETHERYMVSGTNVYGILRAPRSASTESLVLTVPCGP--DATNSQAVGLL 163

Query: 174 LTLARYFKRWSLWSKDIIFVFPPDSKSGTQAWVDAYHDMQPPTVQPLPL--KSGALQGGL 231
           L LA +F+    W+KDIIF+       GT+AW++AYHD+    +Q  PL  ++GA+Q  +
Sbjct: 164 LALAAHFRGQIYWAKDIIFLVTDHDLLGTEAWLEAYHDINVTGIQSSPLQGRAGAIQAAV 223

Query: 232 AIEYPFDHRFENLHIIYDGVNGQLPNLDLFNTAVSIA---GGQMGIGTRLQ-EMWDHNGS 287
           A+E   D    +L +  +G+NGQLPNLDL N   +     G    +  +LQ + W     
Sbjct: 224 ALELSSD-VVTSLDVTVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPQDWTSLEG 282

Query: 288 YEKRLQTMLRGMVKQGLGYAAGAHSSFMPYHIDAITLQTQGNGWQ---DEMALGRTVESL 344
             + LQT+L  +++Q  G   G H  F+ Y ++A+TL+   +  Q   D   +G+ +E +
Sbjct: 283 PLQGLQTLLLMVLRQASGRPHGPHGLFLRYGVEALTLRGINSFRQYKYDLATVGKALEGM 342

Query: 345 CRSLNNLLEHLHQSFFFYLLMQTHRFVSIGTYLPSAMLIAGNFTIMAIALWLRTGYYKDS 404
            R LN+LLE LHQSFFFYLL    RFVSIG Y+P+   +     + A+ LW++       
Sbjct: 343 FRKLNHLLERLHQSFFFYLLPALSRFVSIGLYMPATGFLLLVLGLKALELWMQL------ 396

Query: 405 TQAATVSARLVRDENITTSESEKAQLASKDRNETAPTTGNPATKAAERQLALPLTLIIGL 464
                          +   E+ K           AP+ G P        LA     ++  
Sbjct: 397 -----------HQAGVNPEEAGK-----------APSPGTPLLPTQGVGLASLTAPLLIS 434

Query: 465 HLIGLIPLYIF----NNISHDKYTLATYTSIAINAILPICLSFILSRITTPTQISHQ--- 517
             +GL  LY       +++   + +A   ++    +L I ++ +     T   ++ Q   
Sbjct: 435 QAMGL-ALYFLPVLGQHLATQHFPVAEAEAVV-LTLLAIYVAGLALPHNTHRVVNSQVPD 492

Query: 518 --LHLIKSLSLLPLGLFLSTLATLNFSLSFMTGLLCTPLSFMHIFDAKTKPFVRYTLSAF 575
                +K ++L+ L L L  +A LNFSL F+      P +      A  KP    TL A 
Sbjct: 493 RGWMALKLVALIYLALQLGCIALLNFSLGFLLAATMVPAA------ALAKPHGPRTLYA- 545

Query: 576 GMAFLNVISPPVVLLVGFLTEAAFG 600
             A L V SP V L           
Sbjct: 546 --ALLVVTSPAVTLFGSLFLWRELL 568
>ref|NP_003792.1| anchor attachment protein 1; glycophosphatidylinositol anchor
           attachment 1; anchor attachment protein 1 (Gaa1p, yeast)
           homolog [Homo sapiens]
 dbj|BAA24035.1| hGAA1 [Homo sapiens]
 dbj|BAA82588.1| glycosylphosphatidylinositol anchor attachment 1 (GPAA1) [Homo
           sapiens]
 dbj|BAA82590.1| glycosylphosphatidylinositol anchor attachment 1 (GPAA1) [Homo
           sapiens]
 gb|AAH03171.1| Anchor attachment protein 1 [Homo sapiens]
 gb|AAH04129.1| Anchor attachment protein 1 [Homo sapiens]
          Length = 621

 Score =  611 bits (1559), Expect = e-173
 Identities = 171/624 (27%), Positives = 271/624 (43%), Gaps = 82/624 (13%)

Query: 1   MALKSSLRNLRNNPYFLFVRLPYLLSFLCIVSGVIWLFLLPLDDYSRKTYISENALLPGQ 60
           M L S     R     L +RL   L  L  V+G+ W   L     +++TY+SENA+    
Sbjct: 1   MGLLSDPVRRRALAR-LVLRLNAPLCVLSYVAGIAWFLALVFPPLTQRTYMSENAMGSTM 59

Query: 61  VHAYFAGSEQNVFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQSILMASGLKVAT 120
           V   FAG                     +       ++   +    ++  + + GL+V T
Sbjct: 60  VEEQFAGG--------------DRARAFARDFAAHRKKSGALPVAWLERTMRSVGLEVYT 105

Query: 121 QGYEYK--SSGITHQ-----GENIYAIIQAPRGDATEAIVLVAAWKTIDGQLNLNGVSLA 173
           Q +  K      TH+     G N+Y I++APR  +TE++VL     +     N   V L 
Sbjct: 106 QSFSRKLPFPDETHERYMVSGTNVYGILRAPRAASTESLVLTVPCGS--DSTNSQAVGLL 163

Query: 174 LTLARYFKRWSLWSKDIIFVFPPDSKSGTQAWVDAYHDMQPPTVQPLPL--KSGALQGGL 231
           L LA +F+    W+KDI+F+       GT+AW++AYHD+    +Q  PL  ++GA+Q  +
Sbjct: 164 LALAAHFRGQIYWAKDIVFLVTEHDLLGTEAWLEAYHDVNVTGMQSSPLQGRAGAIQAAV 223

Query: 232 AIEYPFDHRFENLHIIYDGVNGQLPNLDLFNTAVSIA---GGQMGIGTRLQ-EMWDHNGS 287
           A+E   D    +L +  +G+NGQLPNLDL N   +     G    +  +LQ E W     
Sbjct: 224 ALELSSD-VVTSLDVAVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPEDWTSLDG 282

Query: 288 YEKRLQTMLRGMVKQGLGYAAGAHSSFMPYHIDAITLQTQGNGW---QDEMALGRTVESL 344
             + LQT+L  +++Q  G   G+H  F+ Y ++A+TL+   +      D +A+G+ +E +
Sbjct: 283 PLQGLQTLLLMVLRQASGRPHGSHGLFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGM 342

Query: 345 CRSLNNLLEHLHQSFFFYLLMQTHRFVSIGTYLPSAMLIAGNFTIMAIALWLRTGYYKDS 404
            R LN+LLE LHQSFF YLL    RFVSIG Y+P+   +     + A+ LW++       
Sbjct: 343 FRKLNHLLERLHQSFFLYLLPGLSRFVSIGLYMPAVGFLLLVLGLKALELWMQL------ 396

Query: 405 TQAATVSARLVRDENITTSESEKAQLASKDRNETAPTTGNPATKAAERQLALPLTLIIGL 464
                       +  +   E              AP    P   +    LA  +  ++  
Sbjct: 397 -----------HEAGMGLEEPG-----------GAPGPSVPLPPSQGVGLASLVAPLLIS 434

Query: 465 HLIGLIPLYIF----NNISHDKYTLATYTSIAINAILPICLSFILSRITTPTQISHQ--- 517
             +GL  LY+      +++   + +A   ++    +L I  + +     T   +S Q   
Sbjct: 435 QAMGL-ALYVLPVLGQHVATQHFPVAEAEAVV-LTLLAIYAAGLALPHNTHRVVSTQAPD 492

Query: 518 --LHLIKSLSLLPLGLFLSTLATLNFSLSFMTGLLCTPLSFMHIFDAKTKPFVRYTLSAF 575
                +K ++L+ L L L  +A  NFSL F+      P +      A  KP    TL A 
Sbjct: 493 RGWMALKLVALIYLALQLGCIALTNFSLGFLLATTMVPTA------ALAKPHGPRTLYA- 545

Query: 576 GMAFLNVISPPVVLLVGFLTEAAF 599
             A L + SP   LL         
Sbjct: 546 --ALLVLTSPAATLLGSLFLWREL 567
>ref|NP_572273.2| CG3033-PA [Drosophila melanogaster]
 gb|AAF46094.1| CG3033-PA [Drosophila melanogaster]
          Length = 674

 Score =  582 bits (1487), Expect = e-165
 Identities = 175/685 (25%), Positives = 283/685 (40%), Gaps = 107/685 (15%)

Query: 1   MALKSSL--RNLRNNPYFLFVRLPYLLSFLCIVSGVIWLFLLPLDDYSRKTYISENALLP 58
           M L S             L   +  +  +   V+GV W F L L +++  TY+SENAL P
Sbjct: 1   MGLLSDPSISTQSKLVDGLARHVRKV-CYALYVAGVAWFFCLALPEFNHGTYLSENALSP 59

Query: 59  GQVHAYFAGSEQNVFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQSILMASGLKV 118
           G V+         +     +EL+           +++ +  +      I + +   GL+ 
Sbjct: 60  GLVYPEIRIDANRLAIQLLEELQ-----------RERKDHLSTTPHAWIAAKMNEFGLET 108

Query: 119 ATQGYEYK---SSGITHQGENIYAIIQAPRGDATEAIVLVAAWK--TIDGQLNLNGVSLA 173
            T  Y  +     G  + G+NIY I++APR  +TE IV  A ++  +         V L 
Sbjct: 109 HTHNYTLRYPFGGGKEYHGKNIYGILRAPRIASTEGIVFAAPYRAASSVHTDISASVPLL 168

Query: 174 LTLARYFKRWSLWSKDIIFVFPPDSKSGTQAWVDAYHDMQPP--------TVQPLPLKSG 225
           L  A + +R + W+KD+IF+     + G QAW++AYHD                LP ++G
Sbjct: 169 LAFADFARRKNYWAKDLIFLITEQEQLGMQAWLEAYHDGDRELDLSKAYLRPGNLPARAG 228

Query: 226 ALQGGLAIEYPFDHRFENLHIIYDGVNGQLPNLDLFNTAVSI---AGGQMGIGTRLQEMW 282
           +LQ  L IE   D   +++ +  +G+NG+LPNLD+FN    I    G   G     ++  
Sbjct: 229 SLQAALNIEVQ-DLEIDHVDVRIEGLNGKLPNLDMFNLVQRIMAREGIASGYKQAPRKKR 287

Query: 283 DHNGS-YEKRLQTMLRGMVKQGLGYAAGAHSSFMPYHIDAITL---------QTQGNGWQ 332
            H+ S +E+  + ML  +  Q  G   G H  F  Y IDA+T+           +G+   
Sbjct: 288 RHSQSHFEQNFRQMLTMLASQSSGVPTGNHGLFHRYRIDALTIAANRRATHATLKGSPGS 347

Query: 333 DEMALGRTVESLCRSLNNLLEHLHQSFFFYLLMQTHRFVSIGTYLPSAMLIAGNFTIMAI 392
             + L + +E + RSLNNLLE  HQSFFFY+++   R++SIG Y+P+ + +     + A 
Sbjct: 348 AAVPLLKAIEGIARSLNNLLERFHQSFFFYVIVSNDRYISIGDYMPALVALVACAFLKAY 407

Query: 393 ALWLRTGYYKDSTQAATVSARLVRDENITTSESEKAQLASKDRNETAPTTGNPATKAAER 452
             W            +T+ A        T +E EKA    ++  + A    N      E 
Sbjct: 408 LTW------------STLPA--------TNAELEKAAGWLREHEQEAELEENLEPDKFEL 447

Query: 453 Q-----LALPLTLIIGLHLIGLIPL-YIFNNISHDKYTLATYTSIAINAILPICLSFILS 506
                 + L  TL+IG  L  ++PL   F  I      L T   ++  +++   L F++ 
Sbjct: 448 PYGSVLIYLTATLLIGF-LCNVLPLQQYFLEIPMGAAPLTTS-VLSFLSLIGFVLPFVV- 504

Query: 507 RITTPTQISHQLHLIKSLSLLPLGLFLSTLATLNFSLSFMTGLLCTPLSFMHIFDAKTKP 566
            +  P      L L+    LL  G  L  +  LNF+L     +L  PL        +   
Sbjct: 505 -VLPPGG----LELLHVAFLLIYGCALIVIGLLNFALGLFAAVLTVPLVIALETKEENS- 558

Query: 567 FVRYTLSAFGMAFLNVISPPVVLLVGFLTEAAF--------------------------G 600
             R TL         V++P +V+ V       F                           
Sbjct: 559 --RSTLRNTIRLATLVMNPMMVVYVIV-LAMTFYQFPELPVQKIMLRAATAAMDASAYGL 615

Query: 601 WD--VWGMWTQVVVWCVWWPAWVVG 623
            D  ++G W   V+  ++ P W++ 
Sbjct: 616 IDSVIYGNWLYFVICTIFLPLWIIC 640
>ref|XP_331144.1| hypothetical protein [Neurospora crassa]
 gb|EAA30553.1| hypothetical protein [Neurospora crassa]
          Length = 454

 Score =  579 bits (1479), Expect = e-164
 Identities = 281/481 (58%), Positives = 341/481 (70%), Gaps = 36/481 (7%)

Query: 3   LKSSLRNLRNNPYFLFVRLPYLLSFLCIVSGVIWLFLLPLDDYSRKTYISENALLPGQVH 62
           L +S  +LR +P  L  +LP  LS LCIV GV+WLFLLPLDDYSR+TYISENALLPGQVH
Sbjct: 4   LLASALSLRRDPRLL--KLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQVH 61

Query: 63  AYFAGSEQNVFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQSILMASGLKVATQG 122
            YF GS+QNVFR YK E + L      +            +++K++SI    GLKV  Q 
Sbjct: 62  TYFGGSDQNVFRAYKHETDELAGKGNIE------------VNDKLESIAKGLGLKVGRQN 109

Query: 123 YEYKSSGITHQGENIYAIIQAPRGDATEAIVLVAAWKTIDGQLNLNGVSLALTLARYFKR 182
           + Y S+G TH G+NIYAI+QAPRGDATEAIVLVAAWK + G+LN +GV L LTLARYFKR
Sbjct: 110 FTYSSAGNTHSGQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKR 169

Query: 183 WSLWSKDIIFVFPPDSKSGTQAWVDAYHDMQP-PTVQPLPLKSGALQGGLAIEYPFDHRF 241
           WSLWSKDIIF+F PDS +G QAWVDAYHD      V  LPLKSGALQG +A++Y  + RF
Sbjct: 170 WSLWSKDIIFLFTPDSIAGPQAWVDAYHDAHDSSRVASLPLKSGALQGAIALDYTRETRF 229

Query: 242 ENLHIIYDGVNGQLPNLDLFNTAVSIAGGQMGIGTRLQEMWDHNGSYEKRLQTMLRGMVK 301
           +++HI+YDGVNGQLPNLDL N+   +AGGQMG+G  +QEMW H+ SY  RLQTMLRGM+K
Sbjct: 230 QSVHIVYDGVNGQLPNLDLINSVNHVAGGQMGMGVAIQEMWKHSNSYHDRLQTMLRGMLK 289

Query: 302 QGLGYAAGAHSSFMPYHIDAITLQTQGNGWQDEMALGRTVESLCRSLNNLLEHLHQSFFF 361
           QGLG A+G HSSF+PYH+DA+TLQ  G GWQDEMA+GR +E   RSLNNLLEHLHQSFFF
Sbjct: 290 QGLGLASGPHSSFIPYHVDAVTLQPFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQSFFF 349

Query: 362 YLLMQTHRFVSIGTYLPSAMLIAGNFTIMAIALWLRTGYYKDSTQAATVSARLVRDENIT 421
           YLLMQ  RFVSIGTYLPSAML+A NFTIMAIALW+++G                    + 
Sbjct: 350 YLLMQRERFVSIGTYLPSAMLVAANFTIMAIALWVKSGQPD-----------------VQ 392

Query: 422 TSESEKAQLASKDRNETAPTTGNPATKAAERQLALPLTLIIGLHLIGLIPLYIFNNISHD 481
              +EK + A +     +P        A+ER L LPL L+     +G++PLY+FN++S  
Sbjct: 393 EIITEKTKTAEEAERIVSPNPHV----ASERDLFLPLVLVAVCQFLGVVPLYLFNHLSES 448

Query: 482 K 482
            
Sbjct: 449 A 449
>ref|XP_311451.1| ENSANGP00000018454 [Anopheles gambiae]
 gb|EAA07058.1| ENSANGP00000018454 [Anopheles gambiae str. PEST]
          Length = 647

 Score =  570 bits (1455), Expect = e-161
 Identities = 177/667 (26%), Positives = 280/667 (41%), Gaps = 87/667 (13%)

Query: 1   MALKSSLRNLRNNPYFL--FVRLPYLLSFLCIVSGVIWLFLLPLDDYSRKTYISENALLP 58
           M L ++  ++     +    VR    +     + GV +   LP  +++  TY SENALLP
Sbjct: 4   MGLLTNP-SISQKAKYCRKLVRYNTAICLTLYLLGVGFFCALPDANFNSGTYFSENALLP 62

Query: 59  GQVHAYFAGSEQNVFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQSILMASGLKV 118
           G V++       N+ +    EL+   + +              +    + + +   GL+ 
Sbjct: 63  GLVNSELEMETVNLVKSLSSELQRERENY-----------PKGMPYPWLLAKMRRFGLET 111

Query: 119 ATQGYEYK---SSGITHQGENIYAIIQAPRGDATEAIVLVAAWKTID--GQLNLNGVSLA 173
            T  +        G   +GEN+Y I++APR  +TEAIV+   ++  +        GV L 
Sbjct: 112 HTHNFTLNYPFGGGKRFKGENVYGILRAPRIASTEAIVISVPYRPPETVHTDVSAGVPLM 171

Query: 174 LTLARYFKRWSLWSKDIIFVFPPDSKSGTQAWVDAYHDMQPPTVQP---LPLKSGALQGG 230
           L  A + +R   W+KDIIF+     + G QAW++AYH      +     L  ++G++Q  
Sbjct: 172 LAFADFARRKKYWAKDIIFLVTEQEQLGMQAWLEAYHGGDEGRILDSGLLRARAGSIQAA 231

Query: 231 LAIEYPFDHRFENLHIIYDGVNGQLPNLDLFNTAVSIAGGQMGIGTRLQEMWDHNGS--Y 288
           L +E        ++++  +G+NGQLPNLDL N    ++     I    Q       S  Y
Sbjct: 232 LNLEVQS-LDISHINLKIEGLNGQLPNLDLHNLVQKLSSKNGIIAGYKQSSSSPKRSFRY 290

Query: 289 EKRLQTMLRGMVKQGLGYAAGAHSSFMPYHIDAITL------QTQGNGWQDEMALGRTVE 342
           + +L  +L  +  Q  G   G H  F  Y I+A+TL      +TQ   +Q+  ++ R +E
Sbjct: 291 QDKLLNLLSMVFSQASGVPTGNHGLFHKYGIEALTLEAVKRERTQQQQFQEVGSMLRIIE 350

Query: 343 SLCRSLNNLLEHLHQSFFFYLLMQTHRFVSIGTYLPSAMLIAGNFTIMAIALWLRTGYYK 402
            +CRSLNNLLE  HQSFFFYLL+   RFVSIG Y+PS  L+AG   I A   +L   Y  
Sbjct: 351 GICRSLNNLLERFHQSFFFYLLVSNDRFVSIGDYMPSLALMAGALLIKAFIHYLSLYYTG 410

Query: 403 DSTQAATVSARLVRDENITTSESEKAQLASKDRNETAPTTGNPATKAAERQLALPLTLII 462
           D                    E+EK++    D  ET    GN         + L +   +
Sbjct: 411 D------------------NDETEKSE--ETDAVETKQKAGNIDIGYFSVGIVLLVAHTL 450

Query: 463 GLHLIGLIPLYIFNNISHDKYTLATYTSIAINAILPICLSFILSRITTPTQISHQLHLIK 522
           G  ++ L      +N  H+   L+T   +    +  + ++  L    + + I+ +   + 
Sbjct: 451 GALVVLLPQSKAVSNYLHEA-ELSTQFGLFSLFVAVLVVALTLPAFCSLSGINGE--ALH 507

Query: 523 SLSLLPLGLFLSTLATLNFSLSFMTGLLCTPLSFMHIFDAKTKPFVRYTLSAFGMAFLNV 582
              LL LG  L  +  LNFSL F   +L  P      F    +P               +
Sbjct: 508 VAVLLELGTVLLAVGMLNFSLGFSLSVLLVP------FIILIRPAASRGAMFLSRLCCLL 561

Query: 583 ISPPVVLLVGF--LTEAAF-----------------------GWD--VWGMWTQVVVWCV 615
           I+P VVL      LT   F                         D  ++G W   +V  +
Sbjct: 562 INPLVVLYCVLLALTWYLFPELAFKPMLNKALTATMDALTFSVVDSMIYGNWLFDMVSLI 621

Query: 616 WWPAWVV 622
           + P WV+
Sbjct: 622 FVPCWVL 628
>emb|CAD60753.1| unnamed protein product [Podospora anserina]
          Length = 464

 Score =  564 bits (1439), Expect = e-159
 Identities = 272/480 (56%), Positives = 334/480 (68%), Gaps = 43/480 (8%)

Query: 3   LKSSLRNLRNNPYFLFVRLPYLLSFLCIVSGVIWLFLLPLDDYSRKTYISENALLPGQVH 62
           L SS   LR +P  L  ++P  LS LCI+ G +WLFLLPL++YSR+TYISENALLPGQVH
Sbjct: 4   LLSSALALRRDPRIL--KIPPYLSLLCILVGAVWLFLLPLNEYSRRTYISENALLPGQVH 61

Query: 63  AYFAGSEQNVFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQSILMASGLKVATQG 122
            YF GS+QNV R YK+E+  L+     +            I++K++SI+   GLK A Q 
Sbjct: 62  TYFGGSDQNVLRAYKQEVNSLVGKSNVE------------INDKLESIVRGLGLKTARQN 109

Query: 123 YEYKSSGITHQGENIYAIIQAPRGDATEAIVLVAAWKTIDGQLNLNGVSLALTLARYFKR 182
           + Y ++G T +GEN+YAI+QAPRGDATEAIVLVAAW+ +  ++N NGV L LTLARYFKR
Sbjct: 110 FTYHAAGRTFEGENLYAILQAPRGDATEAIVLVAAWENVKHEVNKNGVPLVLTLARYFKR 169

Query: 183 WSLWSKDIIFVFPPDSKSGTQAWVDAYHDMQPP-TVQPLPLKSGALQGGLAIEYPFDHRF 241
           WSLWSKDII +  PDS +  QAWVDAYHD      V  LP+KSGALQG +AI+Y  ++RF
Sbjct: 170 WSLWSKDIIILLSPDSIAAPQAWVDAYHDAHDNSRVASLPIKSGALQGAIAIDYVQENRF 229

Query: 242 ENLHIIYDGVNGQLPNLDLFNTAVSIAGGQMGIGTRLQEMWDHNGSYEKRLQTMLRGMVK 301
           +++HI+YDGVNGQLPNLDL N+ V+IAGGQMG+G  LQEMW+HN  Y  RL+TMLRGM+K
Sbjct: 230 KSVHIVYDGVNGQLPNLDLINSVVNIAGGQMGMGVALQEMWNHNDKYPDRLRTMLRGMLK 289

Query: 302 QGLGYAAGAHSSFMPYHIDAITLQTQGNGWQDEMALGRTVESLCRSLNNLLEHLHQSFFF 361
           QGLG A+G HSSF+PYH+DA+TLQ  G GWQDEMA+GR VE   RSLNNLLEHLHQSFFF
Sbjct: 290 QGLGLASGPHSSFIPYHVDAVTLQPFGEGWQDEMAMGRVVEGTFRSLNNLLEHLHQSFFF 349

Query: 362 YLLMQTHRFVSIGTYLPSAMLIAGNFTIMAIALWLRTGYYKDSTQAATVSARLVRDENIT 421
           YLLM   RFVSIGTYLPSAML+A NFTIMAI LW+++G  +                  T
Sbjct: 350 YLLMHRERFVSIGTYLPSAMLVAANFTIMAIFLWMKSGQPEIP-------------AAST 396

Query: 422 TSESEKAQLASKDRNETAPTTGNPATKAAERQLALPLTLIIGLHLIGLIPLYIFNNISHD 481
           T  S+K         + APT         ER L LPL ++     +  IPLYIFN++   
Sbjct: 397 TESSDK---------DDAPTP------TTERDLFLPLAVVALSGSLSAIPLYIFNHVPES 441
>gb|AAK77275.1| GH05723p [Drosophila melanogaster]
          Length = 561

 Score =  541 bits (1381), Expect = e-152
 Identities = 161/601 (26%), Positives = 258/601 (42%), Gaps = 75/601 (12%)

Query: 1   MALKSSL--RNLRNNPYFLFVRLPYLLSFLCIVSGVIWLFLLPLDDYSRKTYISENALLP 58
           M L S             L   +  +  +   V+GV W F L L +++  TY+SENAL P
Sbjct: 1   MGLLSDPSISTQSKLVDGLARHVRKV-CYALYVAGVAWFFCLALPEFNHGTYLSENALSP 59

Query: 59  GQVHAYFAGSEQNVFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQSILMASGLKV 118
           G V+         +     +EL+           +++ +  +      I + +   GL+ 
Sbjct: 60  GLVYPEIRIDANRLAIQLLEELQ-----------RERKDHLSTTPHAWIAAKMNEFGLET 108

Query: 119 ATQGYEYK---SSGITHQGENIYAIIQAPRGDATEAIVLVAAWK--TIDGQLNLNGVSLA 173
            T  Y  +     G  + G+NIY I++APR  +TE IV  A ++  +         V L 
Sbjct: 109 HTHNYTLRYPFGGGKEYHGKNIYGILRAPRIASTEGIVFAAPYRAASSVHTDISASVPLL 168

Query: 174 LTLARYFKRWSLWSKDIIFVFPPDSKSGTQAWVDAYHDMQPP--------TVQPLPLKSG 225
           L  A + +R + W+KD+IF+     + G QAW++AYHD                LP ++G
Sbjct: 169 LAFADFARRKNYWAKDLIFLITEQEQLGMQAWLEAYHDGDRELDLSKAYLRPGNLPARAG 228

Query: 226 ALQGGLAIEYPFDHRFENLHIIYDGVNGQLPNLDLFNTAVSI---AGGQMGIGTRLQEMW 282
           +LQ  L IE   D   +++ +  +G+NG+LPNLD+FN    I    G   G     ++  
Sbjct: 229 SLQAALNIEVQ-DLEIDHVDVRIEGLNGKLPNLDMFNLVQRIMAREGIASGYKQAPRKKR 287

Query: 283 DHNGS-YEKRLQTMLRGMVKQGLGYAAGAHSSFMPYHIDAITL---------QTQGNGWQ 332
            H+ S +E+  + ML  +  Q  G   G H  F  Y IDA+T+           +G+   
Sbjct: 288 RHSQSHFEQNFRQMLTMLASQSSGVPTGNHGLFHRYRIDALTIAANRRATHATLKGSPGS 347

Query: 333 DEMALGRTVESLCRSLNNLLEHLHQSFFFYLLMQTHRFVSIGTYLPSAMLIAGNFTIMAI 392
             + L + +E + RSLNNLLE  HQSFFFY+++   R++SIG Y+P+ + +     + A 
Sbjct: 348 AAVPLLKAIEGIARSLNNLLERFHQSFFFYVIVSNDRYISIGDYMPALVALVACAFLKAY 407

Query: 393 ALWLRTGYYKDSTQAATVSARLVRDENITTSESEKAQLASKDRNETAPTTGNPATKAAER 452
             W            +T+ A        T +E EKA    ++  + A    N      E 
Sbjct: 408 LTW------------STLPA--------TNAELEKAAGWLREHEQEAELEENLEPDKFEL 447

Query: 453 Q-----LALPLTLIIGLHLIGLIPL-YIFNNISHDKYTLATYTSIAINAILPICLSFILS 506
                 + L  TL+IG  L  ++PL   F  I      L T   ++  +++   L F++ 
Sbjct: 448 PYGSVLIYLTATLLIGF-LCNVLPLQQYFLEIPMGAAPLTTS-VLSFLSLIGFVLPFVV- 504

Query: 507 RITTPTQISHQLHLIKSLSLLPLGLFLSTLATLNFSLSFMTGLLCTPLSFMHIFDAKTKP 566
            +  P      L L+    LL  G  L  +  LNF+L     +L  PL        +   
Sbjct: 505 -VLPPGG----LELLHVAFLLIYGCALIVIGLLNFALGLFAAVLTVPLVIALETKEENSA 559

Query: 567 F 567
            
Sbjct: 560 A 560
>gb|AAH06383.2| GPAA1 protein [Homo sapiens]
          Length = 561

 Score =  528 bits (1348), Expect = e-148
 Identities = 149/523 (28%), Positives = 238/523 (45%), Gaps = 67/523 (12%)

Query: 102 VISEKIQSILMASGLKVATQGYEYK--SSGITHQ-----GENIYAIIQAPRGDATEAIVL 154
           +    ++  + + GL+V TQ +  K      TH+     G N+Y I++APR  +TE++VL
Sbjct: 27  LPVAWLERTMRSVGLEVYTQSFSRKLPFPDETHERYMVSGTNVYGILRAPRAASTESLVL 86

Query: 155 VAAWKTIDGQLNLNGVSLALTLARYFKRWSLWSKDIIFVFPPDSKSGTQAWVDAYHDMQP 214
                +     N   V L L LA +F+    W+KDI+F+       GT+AW++AYHD+  
Sbjct: 87  TVPCGS--DSTNSQAVGLLLALAAHFRGQIYWAKDIVFLVTEHDLLGTEAWLEAYHDVNV 144

Query: 215 PTVQPLPL--KSGALQGGLAIEYPFDHRFENLHIIYDGVNGQLPNLDLFNTAVSIA---G 269
             +Q  PL  ++GA+Q  +A+E   D    +L +  +G+NGQLPNLDL N   +     G
Sbjct: 145 TGMQSSPLQGRAGAIQAAVALELSSD-VVTSLDVAVEGLNGQLPNLDLLNLFQTFCQKGG 203

Query: 270 GQMGIGTRLQ-EMWDHNGSYEKRLQTMLRGMVKQGLGYAAGAHSSFMPYHIDAITLQTQG 328
               +  +LQ E W       + LQT+L  +++Q  G   G+H  F+ Y ++A+TL+   
Sbjct: 204 LLCTLQGKLQPEDWTSLDGPLQGLQTLLLMVLRQASGRPHGSHGLFLRYRVEALTLRGIN 263

Query: 329 NGWQ---DEMALGRTVESLCRSLNNLLEHLHQSFFFYLLMQTHRFVSIGTYLPSAMLIAG 385
           +  Q   D +A+G+ +E + R LN+LLE LHQSFF YLL    RFVSIG Y+P+   +  
Sbjct: 264 SFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSFFLYLLPGLSRFVSIGLYMPAVGFLLL 323

Query: 386 NFTIMAIALWLRTGYYKDSTQAATVSARLVRDENITTSESEKAQLASKDRNETAPTTGNP 445
              + A+ LW++                   +  +   E              AP    P
Sbjct: 324 VLGLKALELWMQL-----------------HEAGMGLEEPG-----------GAPGPSVP 355

Query: 446 ATKAAERQLALPLTLIIGLHLIGLIPLYIF----NNISHDKYTLATYTSIAINAILPICL 501
              +    LA  +  ++    +GL  LY+      +++   + +A   ++    +L I  
Sbjct: 356 LPPSQGVGLASLVAPLLISQAMGL-ALYVLPVLGQHVATQHFPVAEAEAVV-LTLLAIYA 413

Query: 502 SFILSRITTPTQISHQ-----LHLIKSLSLLPLGLFLSTLATLNFSLSFMTGLLCTPLSF 556
           + +     T   +S Q        +K ++L+ L L L  +A  NFSL F+      P + 
Sbjct: 414 AGLALPHNTHRVVSTQAPDRGWMALKLVALIYLALQLGCIALTNFSLGFLLATTMVPTA- 472

Query: 557 MHIFDAKTKPFVRYTLSAFGMAFLNVISPPVVLLVGFLTEAAF 599
                A  KP    TL A   A L + SP   LL         
Sbjct: 473 -----ALAKPHGPRTLYA---ALLVLTSPAATLLGSLFLWREL 507
>pir||T32771 hypothetical protein F33D11.9b - Caenorhabditis elegans
          Length = 885

 Score =  514 bits (1311), Expect = e-144
 Identities = 138/644 (21%), Positives = 236/644 (36%), Gaps = 119/644 (18%)

Query: 1   MALKSSLRNLRNN-----PYFL-----FVRLPYLLSFLCIVSGVIWLFLLPLDDYSRKTY 50
           + L      +  +     P  L     F ++  +++++       WLF  P++     T 
Sbjct: 274 LKLLEMALEISKDGGTTRPKILDKILKFRKVALIIAYIGAYLSAQWLF-DPVN--MEVTR 330

Query: 51  ISENALLPGQVHAYF--AGSEQNVFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQ 108
           ISE++L+PG V   F  +G    ++R +            SD  K KS++      E I 
Sbjct: 331 ISEHSLMPGLVTPKFDKSGIAIQLYRRF------------SDLPKSKSQQ------ELIH 372

Query: 109 SILMASGLKVATQGYEYKSSGITHQGENIYAIIQAPRGDATEAIVLVAAWKTIDGQLNLN 168
           +I    GL+  T  +  K +G    GEN+Y  I+ PR D  EA ++V      +    + 
Sbjct: 373 TIFSDLGLECFTHKWRSKVAGNPMNGENVYGFIRGPRNDGAEAQMIVVQLGRSEKSRRM- 431

Query: 169 GVSLALTLARYFKRWSLWSKDIIFVF-----PPDSKSGTQAWVDAY----------HDMQ 213
            +S  L    Y K    W++DI+ VF       DS       +DA+          +  +
Sbjct: 432 -MSRMLAFVDYAKDQVYWARDIVIVFVDGGEKNDSIEKAAFALDAFLLKYQKIEALNSKK 490

Query: 214 PPTVQP--LPLKSGALQGGLAIEYPFDHRFENLHII---YDGVNGQLPNLDLFNTAVSIA 268
             TV+   +  ++GAL GG+  +       +  HI+    +G+NGQ  NLD+FN    IA
Sbjct: 491 SITVEADEIQAQTGALIGGVVYDL-SGMAVKGQHIVNIQTNGLNGQQVNLDVFNGITKIA 549

Query: 269 G----GQMGIGTRLQEMWDHNGSYEKRLQTMLRGMVKQGLGYAAGAHSSFMPYHIDAITL 324
                 ++ I   L    +    Y   +  M R +  Q      G HS    Y +  +T+
Sbjct: 550 DSKHHSRVAIFGTLHRHSNPYMEYSPFIVPM-RALYTQAFISIEGIHSVLGKYGVQGLTV 608

Query: 325 QTQGNGWQDEMALGRTVESLCRSLNNLLEHLHQSFFFYLLMQTHRFVSIGTYLPSAMLIA 384
               +    E   G+ +E + R LNN+LE LHQS+F Y+L     F SI  Y+    ++ 
Sbjct: 609 GLSHD--YSEKQTGQFIEEVSRMLNNVLERLHQSYFMYVLADDLHFSSIAMYIIPLTILV 666

Query: 385 GNFTIMAIALWLRTGYYKDSTQAATVSARLVRDENITTSESEKAQLASKDRNETAPTTGN 444
               I A   W +   ++           +V              +A+    +T  TT  
Sbjct: 667 SPLVISAYFEWTKIQEFQFP---------VVHLAFHVL--GFFYYIATTYVFQTIGTTFV 715

Query: 445 PATKAAERQLALPLTLIIGLHLIGLIPLYIFNNISHDKYTLATYTSIAINAILPICLSFI 504
                 +               +G+            ++T +     +      I L   
Sbjct: 716 LQ--WMQWP------------FVGIDG-------CDGQFTPSWSLINSFLIFFMIPL--- 751

Query: 505 LSRITTPTQISHQLHLIKSLSLLPLGLFLSTLATLN--FSLSFMTGLLCTPLSFMHIFDA 562
                           +K+ S+       S LA LN    L+F+   +  P  F  +F  
Sbjct: 752 -----------GPYVFLKTRSIFRS----SVLAILNPISVLAFV--AINIPGMFGQLFPT 794

Query: 563 KTKPFVRYTLSAFGMAFLNVISPPVVLLVGFLTEAAFGWDVWGM 606
            ++    +  +A  +A   +       +  F     FG+ +W M
Sbjct: 795 ISQD--SWLAAAQSIALTAIREDVEFKVNHFFLLCCFGYPIWNM 836
>pir||T46923 hypothetical protein DKFZp434E1512.1 - human
 emb|CAB75660.1| hypothetical protein [Homo sapiens]
          Length = 499

 Score =  498 bits (1271), Expect = e-139
 Identities = 141/484 (29%), Positives = 222/484 (45%), Gaps = 60/484 (12%)

Query: 134 GENIYAIIQAPRGDATEAIVLVAAWKTIDGQLNLNGVSLALTLARYFKRWSLWSKDIIFV 193
           G N+Y I++APR  +TE++VL     +     N   V L L LA +F+    W+KDI+F+
Sbjct: 4   GTNVYGILRAPRAASTESLVLTVPCGS--DSTNSQAVGLLLALAAHFRGQIYWAKDIVFL 61

Query: 194 FPPDSKSGTQAWVDAYHDMQPPTVQPLPL--KSGALQGGLAIEYPFDHRFENLHIIYDGV 251
                  GT+AW++AYHD+    +Q  PL  ++GA+Q  +A+E   D    +L +  +G+
Sbjct: 62  VTEHDLLGTEAWLEAYHDVNVTGMQSSPLQGRAGAIQAAVALELSSD-VVTSLDVAVEGL 120

Query: 252 NGQLPNLDLFNTAVSIA---GGQMGIGTRLQ-EMWDHNGSYEKRLQTMLRGMVKQGLGYA 307
           NGQLPNLDL N   +     G    +  +LQ E W       + LQT+L  +++Q  G  
Sbjct: 121 NGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPEDWTSLDGPLQGLQTLLLMVLRQASGRP 180

Query: 308 AGAHSSFMPYHIDAITLQTQGNGWQ---DEMALGRTVESLCRSLNNLLEHLHQSFFFYLL 364
            G+H  F+ Y ++A+TL+   +  Q   D +A+G+ +E + R LN+LLE LHQSFF YLL
Sbjct: 181 HGSHGLFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSFFLYLL 240

Query: 365 MQTHRFVSIGTYLPSAMLIAGNFTIMAIALWLRTGYYKDSTQAATVSARLVRDENITTSE 424
               RFVSIG Y+P+   +     + A+ LW++                   +  +   E
Sbjct: 241 PGLSRFVSIGLYMPAVGFLLLVLGLKALELWMQL-----------------HEAGMGLEE 283

Query: 425 SEKAQLASKDRNETAPTTGNPATKAAERQLALPLTLIIGLHLIGLIPLYIF----NNISH 480
                         AP    P   +    LA  +  ++    +GL  LY+      +++ 
Sbjct: 284 PG-----------GAPGPSVPLPPSQGVGLASLVAPLLISQAMGL-ALYVLPVLGQHVAT 331

Query: 481 DKYTLATYTSIAINAILPICLSFILSRITTPTQISHQ-----LHLIKSLSLLPLGLFLST 535
             + +A   ++    +L I  + +     T   +S Q        +K ++L+ L L L  
Sbjct: 332 QHFPVAEAEAVV-LTLLAIYAAGLALPHNTHRVVSTQAPDRGWMALKLVALIYLALQLGC 390

Query: 536 LATLNFSLSFMTGLLCTPLSFMHIFDAKTKPFVRYTLSAFGMAFLNVISPPVVLLVGFLT 595
           +A  NFSL F+      P +      A  KP    TL A   A L + SP   LL     
Sbjct: 391 IALTNFSLGFLLATTMVPTA------ALAKPHGPRTLYA---ALLVLTSPAATLLGSLFL 441

Query: 596 EAAF 599
               
Sbjct: 442 WREL 445
>ref|NP_491700.2| anchor attachment protein 1 (1G434) [Caenorhabditis elegans]
 gb|AAK68360.2| Hypothetical protein F33D11.9b [Caenorhabditis elegans]
          Length = 676

 Score =  494 bits (1261), Expect = e-138
 Identities = 136/631 (21%), Positives = 236/631 (36%), Gaps = 109/631 (17%)

Query: 1   MALKSSLRNLRNN-----PYFL-----FVRLPYLLSFLCIVSGVIWLFLLPLDDYSRKTY 50
           + L      +  +     P  L     F ++  +++++       WLF  P++     T 
Sbjct: 12  LKLLEMALEISKDGGTTRPKILDKILKFRKVALIIAYIGAYLSAQWLF-DPVN--MEVTR 68

Query: 51  ISENALLPGQVHAYF--AGSEQNVFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQ 108
           ISE++L+PG V   F  +G    ++R +            SD  K KS++      E I 
Sbjct: 69  ISEHSLMPGLVTPKFDKSGIAIQLYRRF------------SDLPKSKSQQ------ELIH 110

Query: 109 SILMASGLKVATQGYEYKSSGITHQGENIYAIIQAPRGDATEAIVLVAAWKTIDGQLNLN 168
           +I    GL+  T  +  K +G    GEN+Y  I+ PR D  EA ++V      +    + 
Sbjct: 111 TIFSDLGLECFTHKWRSKVAGNPMNGENVYGFIRGPRNDGAEAQMIVVQLGRSEKSRRM- 169

Query: 169 GVSLALTLARYFKRWSLWSKDIIFVF-----PPDSKSGTQAWVDAY----------HDMQ 213
            +S  L    Y K    W++DI+ VF       DS       +DA+          +  +
Sbjct: 170 -MSRMLAFVDYAKDQVYWARDIVIVFVDGGEKNDSIEKAAFALDAFLLKYQKIEALNSKK 228

Query: 214 PPTVQP--LPLKSGALQGGLAIEYPFDHRFENLHII---YDGVNGQLPNLDLFNTAVSIA 268
             TV+   +  ++GAL GG+  +       +  HI+    +G+NGQ  NLD+FN    IA
Sbjct: 229 SITVEADEIQAQTGALIGGVVYDL-SGMAVKGQHIVNIQTNGLNGQQVNLDVFNGITKIA 287

Query: 269 G----GQMGIGTRLQEMWDHNGSYEKRLQTMLRGMVKQGLGYAAGAHSSFMPYHIDAITL 324
                 ++ I   L    +    Y   +  M R +  Q      G HS    Y +  +T+
Sbjct: 288 DSKHHSRVAIFGTLHRHSNPYMEYSPFIVPM-RALYTQAFISIEGIHSVLGKYGVQGLTV 346

Query: 325 QTQGNGWQDEMALGRTVESLCRSLNNLLEHLHQSFFFYLLMQTHRFVSIGTYLPSAMLIA 384
               +    E   G+ +E + R LNN+LE LHQS+F Y+L     F SI  Y+    ++ 
Sbjct: 347 GLSHD--YSEKQTGQFIEEVSRMLNNVLERLHQSYFMYVLADDLHFSSIAMYIIPLTILV 404

Query: 385 GNFTIMAIALWLRTGYYKDSTQAATVSARLVRDENITTSESEKAQLASKDRNETAPTTGN 444
               I A   W +   ++           +V              +A+    +T  TT  
Sbjct: 405 SPLVISAYFEWTKIQEFQFP---------VVHLAFHVL--GFFYYIATTYVFQTIGTTFV 453

Query: 445 PATKAAERQLALPLTLIIGLHLIGLIPLYIFNNISHDKYTLATYTSIAINAILPICLS-- 502
                 +               +G+            ++T +     +      I L   
Sbjct: 454 LQ--WMQWP------------FVGIDG-------CDGQFTPSWSLINSFLIFFMIPLGPY 492

Query: 503 -FILSRI-TTPTQISHQLHLIKSLSLLPLGLFLSTLATLNFSLSFMTGLLCTPLSFMHIF 560
            F+   +   P+        ++ + LL   L L  +   NF L+ +      P+ F+  +
Sbjct: 493 VFLKEPVRCVPS--------MRIVCLLETSLVLYGICLTNFGLAILCTAFVVPIVFLMTY 544

Query: 561 DAKTKPFVRYTLSAFGMAFLNVISPPVVLLV 591
             ++    R    +  +A LN IS    + +
Sbjct: 545 --ESSDRTRSIFRSSVLAILNPISVLAFVAI 573
>gb|AAH60413.1| Unknown (protein for MGC:68658) [Xenopus laevis]
          Length = 615

 Score =  452 bits (1151), Expect = e-125
 Identities = 132/436 (30%), Positives = 205/436 (46%), Gaps = 34/436 (7%)

Query: 1   MALKSSLRNLRNNPYFLFVRLPYLLSFLCIVSGVIWLFLLPLDDYSRKTYISENALLPGQ 60
           M L S   N R     +  +L   L     + GV+W   L    ++ ++YISEN++    
Sbjct: 1   MGLLSDP-NRRQALSRIITQLNTPLCIFSYLVGVVWFLGLAFHPFTLRSYISENSMGSTM 59

Query: 61  VHAYFAGSEQNVFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQSILMASGLKVAT 120
           V   F   E+ V   Y +E                 +         ++  +   GL+V +
Sbjct: 60  VEEQFVSGERAV--SYAREF------------AAHKKSAGGSPVAWLERTMSGLGLEVYS 105

Query: 121 QGY--EYKSSGIT-----HQGENIYAIIQAPRGDATEAIVLVAAWKTIDGQLNLNGVSLA 173
           Q +         T      +G N+Y I++APR  +TE++VL       +GQ N   V L 
Sbjct: 106 QSFVRTLPFPDETTERFMVKGTNVYGILRAPRAASTESLVLSVPC--SEGQNNNQAVGLL 163

Query: 174 LTLARYFKRWSLWSKDIIFVFPPDSKSGTQAWVDAYHDMQPPTVQPLPL--KSGALQGGL 231
           L LA YF+    W+KDIIF+       G +AW++ YHD+    ++   +  ++GA+Q  +
Sbjct: 164 LALASYFRGQIYWAKDIIFLVNEHDLIGMEAWLEGYHDVNVTEIKSSVMIGRAGAIQAAV 223

Query: 232 AIEYPFDHRFENLHIIYDGVNGQLPNLDLFNTAVSIAGGQ---MGIGTRLQ-EMWDHNGS 287
           ++E   D    +  ++ +G+NGQLPNLDL +   +          I  +LQ   +D    
Sbjct: 224 SLEMSSD-VVTSFDLVVEGLNGQLPNLDLVSLFYAFCQKNALLCTIQGKLQRNDFDTFPG 282

Query: 288 YEKRLQTMLRGMVKQGLGYAAGAHSSFMPYHIDAITLQTQGNGWQ---DEMALGRTVESL 344
           Y   LQTML  ++KQG G   G H  F+ YHI+AITL+   +  Q   D   +G+T+E +
Sbjct: 283 YLHSLQTMLIMVLKQGAGRPQGDHGLFLRYHIEAITLRGINSFRQYKYDLSTVGKTLEGM 342

Query: 345 CRSLNNLLEHLHQSFFFYLLMQTHRFVSIGTYLPSAMLIAGNFTIMAIALWLRTGYYKDS 404
            R LNNL E LHQS+FFYLL    RFVSIG Y+P+   I     + ++ LW++  +    
Sbjct: 343 FRKLNNLSERLHQSYFFYLLPCLSRFVSIGIYMPAVGFIILILILRSLDLWIKLRHSDGR 402

Query: 405 TQAATVSARLVRDENI 420
           T+   +         I
Sbjct: 403 TEDGVMDTEQDPRPGI 418
 Score =  151 bits (380), Expect = 5e-35
 Identities = 39/220 (17%), Positives = 75/220 (33%), Gaps = 44/220 (20%)

Query: 435 RNETAPTTGNPATKAAERQ-LALPLTLIIGLHLIGLIPLYIF----NNISHDKYTLATYT 489
            ++     G   T+   R  +    T I+  H  GL  LY        ++ D + ++   
Sbjct: 398 HSDGRTEDGVMDTEQDPRPGILSLATPIVICHATGL-SLYYLPVMSQEMATDHFPVSESE 456

Query: 490 SIAINAILPICLSFILSRITTPTQIS-----HQLHLIKSLSLLPLGLFLSTLATLNFSLS 544
           ++     + I ++ +     T   ++          +K +SLL L + L  ++ +NFSL 
Sbjct: 457 AVV-LTAIAIYVAGLALPHNTHRVLTGAGSEQGWMTLKLISLLYLAVLLGCISLINFSLG 515

Query: 545 FMTGLLCTPLSFMHIFDAKTKPFVRYTLSAFGMAFLNVISPPVVLLVGFLTEAAF----- 599
           F+  +   P++      A  +P     L A     L +I+P   LL              
Sbjct: 516 FLLAITIVPVA------AIVQPTGPRALYA---ILLVLITPATTLLGSIFLYRELIEYPV 566

Query: 600 ----GWD--------------VWGMWTQVVVWCVWWPAWV 621
               GW               ++G      +    +P W+
Sbjct: 567 SVLEGWQLFLQAIAGGMLDHYLYGSLLFPFIAFFVYPCWL 606
>ref|NP_593498.1| putative glycosylphosphatidylinositol anchor attachment protein
           [Schizosaccharomyces pombe]
 emb|CAB65611.1| SPAC1002.11 [Schizosaccharomyces pombe]
          Length = 581

 Score =  405 bits (1031), Expect = e-111
 Identities = 148/405 (36%), Positives = 216/405 (52%), Gaps = 19/405 (4%)

Query: 1   MALKSSLRNLRNNPYFLFVRLPYLLSFLCIVSGVIWLFLLPLDDYSRKTYISENALLPGQ 60
           M+L +    +R  P FL   L + L     + G+ W+F+LP ++   + ++SE+ALLPGQ
Sbjct: 1   MSLFT-FVQIRVFP-FLQRHL-FFLQLSLTLIGLSWIFILPRNEIIDRLHVSESALLPGQ 57

Query: 61  VHAYFAGSEQNVFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQSILMASGLKVAT 120
           V+ YF          Y K +   L    +      S   T  + + ++ I  A GL    
Sbjct: 58  VNTYFEN-------RYSKTVSSSLTAANTWSHLDASVG-TNTMYDDLEQIFTAMGLPTQK 109

Query: 121 QGYEYKSSGITHQGENIYAIIQAPRGDATEAIVLVAAWKTIDGQLNLNGVSLALTLARYF 180
           Q Y     G    G N    ++APRGDATE+++L   WK   GQ N  GV+LA++L +YF
Sbjct: 110 QNYSINIPGSEFNGSNFITTLRAPRGDATESLLLCVPWKDHIGQYNEAGVALAISLLKYF 169

Query: 181 KRWSLWSKDIIFVFPPDSKSGTQAWVDAYHDMQPPTV--QPLPLKSGALQGGLAIE-YPF 237
           + WSLWSKDII V   D   G  +++ +Y D   P +   PL ++SG++Q GL++E    
Sbjct: 170 QGWSLWSKDIILVIFDDPVYGPSSFLTSYFDQTTPYISYTPLKIRSGSIQAGLSLELVTT 229

Query: 238 DHRFENLHIIYDGVNGQLPNLDLFNTAVSIAGGQMGIGTRLQEMWDHNG---SYEKRLQT 294
           ++  + L ++Y   NGQLPNLDLFNT   I         RLQ    H     SY  RL++
Sbjct: 230 ENNSDVLEVLYQATNGQLPNLDLFNTISRIFMQHFNYPLRLQGYDFHANSGSSYTSRLKS 289

Query: 295 MLRGMVKQGLGYAAGAHSSFMPYHIDAITLQTQGN--GWQDEMALGRTVESLCRSLNNLL 352
           +  GM+ Q +     AH+ F  Y ID +TL+ +       D    G+ +ES  RSLNNLL
Sbjct: 290 LWMGMLTQAVSNVTSAHALFPQYRIDMLTLRMKVKDPFSFDMFRFGQAIESTFRSLNNLL 349

Query: 353 EHLHQSFFFYLLMQTHRFVSIGTYLPSAMLIAGNFTIMAIALWLR 397
           EHLHQSFFFY ++    F+SIG Y+PS +++A +F + A   W+ 
Sbjct: 350 EHLHQSFFFYFILDHLHFISIGNYMPSILILAASFMLGAYRHWIN 394
 Score = 44.7 bits (105), Expect = 0.008
 Identities = 37/166 (22%), Positives = 67/166 (40%), Gaps = 14/166 (8%)

Query: 452 RQLALPLTLIIGLHLIGLIPLYIFNNISHDKYTLATYTSIAINAILPICLSFILSRITTP 511
             L  P +  +      +   Y+          +++ T I +   L + L+FI    +T 
Sbjct: 399 IDLWRPFSFWLFSIFCTIAAYYL----------VSSSTKITVFIFLYLMLTFIGIIFSTF 448

Query: 512 TQISHQLHLIKSLSLLPLGLFLSTLATLNFSLSFMTGLLCTPLSFM--HIFDAKTKPFVR 569
              S    L+ S  L+   LF+S ++TLNFSLSF+  +L  PL F+        +  F  
Sbjct: 449 -MTSEDAELVLSYDLMSKSLFISVVSTLNFSLSFVVAILLVPLQFISFRFNRRLSLLFAV 507

Query: 570 YTLSAFGMAFLNVISPPVVLLVGFLTEAAFGWDVWGMWTQVVVWCV 615
            T  +  +   ++       LV F   A   ++++  W    V+ +
Sbjct: 508 LTYFSTFIFLCSLSKILNGPLVPFWLWAK-EYELFNSWLMPSVFMI 552
>ref|NP_916949.1| putative GPAA1 - like protein [Oryza sativa (japonica
           cultivar-group)]
 dbj|BAC01259.1| putative GPAA1 - like protein [Oryza sativa (japonica
           cultivar-group)]
          Length = 718

 Score =  355 bits (902), Expect = 3e-96
 Identities = 90/471 (19%), Positives = 174/471 (36%), Gaps = 98/471 (20%)

Query: 223 KSGALQGGLAIEYPFDHRFENLHIIY---DGVNGQLPNLDLFNTAVSIAGGQMGIGTRLQ 279
           ++G +   L  +     ++ +   +    +  NGQ+PNLDL N    +A  + G    ++
Sbjct: 268 RAGTMAAALIFKVGETRKYGDRDSVTMYAEASNGQMPNLDLLNVVHYLAVHRQGFRVNVE 327

Query: 280 ---------------EMWDHNGSYEKRLQT-----------------MLRGMVKQGLGYA 307
                          E++ + GS  +++                   +   M  Q LG  
Sbjct: 328 TFNSLLSSSWLRVIAEVFQNLGSLLRKINPDWKLDVTVPDYVEGTANLASSMYNQALGVP 387

Query: 308 AGAHSSFMPYHIDAITLQ------TQGNGWQDEMAL--GRTVESLCRSLNNLLEHLHQSF 359
            G+H +F  Y +DA++L+       +    +    L  GR  E + RS+NNLLE  HQSF
Sbjct: 388 TGSHGAFRDYQVDAVSLEFAPAFHLKNENAKSSFLLRGGRLTEGVVRSVNNLLEKFHQSF 447

Query: 360 FFYLLMQTHRFVSIGTYLPSAMLIAGNFTIMAIALWLRTGYYKDSTQAATVSARLVRDEN 419
           F Y L    +F+S+G Y+    L+     I+A AL                         
Sbjct: 448 FLYFLTAPSKFISVGVYMIPFALLLAPLPIVAAAL------------------------- 482

Query: 420 ITTSESEKAQLASKDRNETAPTTGNPATKAAERQLALPLTLIIGLHL----IGLIPLYIF 475
              +   K +   +D  +T     +   +    +      +++ +      + L+P Y  
Sbjct: 483 ---AGGSKTKGKLEDECKTKGNADDLQMEGGSWKWLKSARVLLIIQFWAVLVSLLP-YYI 538

Query: 476 NNISHDKYTLATYTSIAINAILPICLSFILSRITTPTQISHQLHLIKSLSLLPLGLFLST 535
           + I      +      A+ +I  + +  + +   +P++   +  L+K+  +  + + +  
Sbjct: 539 SQIP-GAMPIQYAVIWAVLSITILII--LYAMFGSPSRAGVEWKLLKATMITSITIGMGL 595

Query: 536 LATLNFSLSFMTGLLCTPLS-FMHIFDA-KTKPFVRYT-LSAFGMAFLNVISPPVVLL-- 590
           ++ +NF+ + +  L+  P+  F     A     F+  T L A  +    +  PP   L  
Sbjct: 596 MSIINFATAQLGALILIPMCLFSRPLRAQLEMNFLPRTVLLASNILLTVLGFPPAAFLIM 655

Query: 591 -------------VGFLTEAAFGWDVWGMWTQVVVWCVWWPAWVVGGVVLG 628
                          F     F W+ W   T + V+ V  P W++   VL 
Sbjct: 656 KGLSKGSWTVDIVGDFWLWMEFLWE-WSSATYLYVFLVHLPCWLLCIHVLL 705
 Score =  178 bits (448), Expect = 5e-43
 Identities = 62/231 (26%), Positives = 100/231 (42%), Gaps = 27/231 (11%)

Query: 5   SSLRNLRNNPYFLFVRLPYLL-------SFLCIVSGVIWLFLLPLDDYSRKTYISENALL 57
           SS +        L VRL   L       S +C  +G+I L  LP    ++ TY+SENAL+
Sbjct: 3   SSAKEEAKPKPRLIVRLGVFLASHHILFSAVCCTAGIIALLFLP--SLAKNTYLSENALI 60

Query: 58  PGQVHAYFAGSEQNVFRGYKKELEGLLD-GHGSDGEKKK--SEERTQVISEKIQSILMAS 114
           PG  +  F+  +      + K +E  +    G   E  K  +++   + +E      +  
Sbjct: 61  PGSANTLFSTEDVQEANRFAKGIEAAIGESRGGTTEIPKFIAQQTKNLGAEVYYHEFLPD 120

Query: 115 G--------LKVATQGYEYKSSGI-THQGENIYAIIQAPRGDATEAIVLVAAWKTIDGQL 165
                        T     K +G  T+ G N   II+APRGD  EAIVLV  + +     
Sbjct: 121 SKCFHPLKFFTSMTNNMAAKPNGTYTNFGINTVGIIRAPRGDGKEAIVLVTPYNSQKVTP 180

Query: 166 NL-NGVSLALTLARYFKRWSLWSKDIIFVFPPDSKSG----TQAWVDAYHD 211
           N    ++L  ++     R +  SKDI+++   DS+ G      +W++ YH+
Sbjct: 181 NELLSLALGFSVFSLLSRAAWLSKDIVWL-SADSQFGEYSAVSSWLNQYHN 230
>gb|EAA16082.1| hypothetical protein [Plasmodium yoelii yoelii]
          Length = 489

 Score =  335 bits (852), Expect = 2e-90
 Identities = 71/404 (17%), Positives = 129/404 (31%), Gaps = 72/404 (17%)

Query: 11  RNNPYF------LFVRLPYLLSFLCIVSGVIWLFLLPLDDYSRK--------TYISENAL 56
             NP F      +  R   +   L I   + + +   +D   +K             N+ 
Sbjct: 4   SENPTFYLLIDKIIRRSKIIGLTLSI---IGFFYFCVIDKIDKKAELDARSFAQFPGNST 60

Query: 57  LPGQVHAYFAGSEQNVFRGYKKELEGLLDGHGSDGEKKKSEERTQVISE-KIQSILMASG 115
           L  +    F    +  F  YK E    +     D  K+ S        E KI   +    
Sbjct: 61  L-TKDDEDFLNETKYYFENYKYEEREHVIDIVHDYIKRMSSLVDTKKCEIKINDKVKDY- 118

Query: 116 LKVATQGYEYKSSGITHQGENIYAIIQAPRGDATEAIVLVAAWKTIDGQLNLNGVSLALT 175
                      + G                 +  E +++V  +   + +   + + + LT
Sbjct: 119 -------ILISNVGCKF-------------CNNIENLIVVINFDYKERKY-FHSLVVGLT 157

Query: 176 LARYFKRWSLWSKDIIFVFPPDSK---SGTQAWVDAYHDMQPPTVQPLPLKSGALQGGLA 232
           L  YF   +  SKDIIF+F         G + +++ Y+       + L       +  + 
Sbjct: 158 LINYFLNANYMSKDIIFLFTNKELLYSLGVKNFIEHYYYGNTENRKVL------TRSSII 211

Query: 233 IEYPFDHRFENLHIIYDGVNGQLPNLDLFNTAVSIAGGQMGIGTRLQEMWDHNGSYEKRL 292
           IE+       N+ I Y+ +NG LPN DL                 L+   +H      + 
Sbjct: 212 IEFES-IYPSNIEINYESLNGMLPNQDLILL--------------LRNELNHYNIPM-KT 255

Query: 293 QTMLRGMVKQGLGYA-AGAHSSFMPYHIDAITLQTQGN-----GWQDEMALGRTVESLCR 346
             +   ++   L       H  F+  +I + T+             +     ++++S  R
Sbjct: 256 DPVYHAILNVALEKKYEKGHIYFLRENIPSFTITGVSKVPLKRKMINLFNFTKSLQSFLR 315

Query: 347 SLNNLLEHLHQSFFFYLLMQTHRFVSIGTYLPSAMLIAGNFTIM 390
           S +N  E    S  FY      ++V I  Y+    LI     + 
Sbjct: 316 SQSNTHEGFCHSTNFYFFNTIKKYVPISLYVFCVYLICSYCILK 359
>ref|NP_705572.1| hypothetical protein [Plasmodium falciparum 3D7]
 emb|CAD52809.1| hypothetical protein [Plasmodium falciparum 3D7]
          Length = 810

 Score =  330 bits (840), Expect = 5e-89
 Identities = 73/418 (17%), Positives = 131/418 (30%), Gaps = 83/418 (19%)

Query: 11  RNNPYF------LFVRLPYLLSFLCIVSGVIWLFLLPLDDYSRK--------TYISENAL 56
             NP F      L  +   +  FL I   +  +F L  + +++         T    N++
Sbjct: 4   SENPKFCLLINKLIKKSKVIGVFLSI---IGVIFFLVFNKFNKNAELDARTFTQFVGNSV 60

Query: 57  LPGQVHAYFAGSEQNVFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQSILMASGL 116
           L  + +  F     + F  Y  E +  +     D        R  ++      ++     
Sbjct: 61  L-NKKNEKFYNDTNSYFMNYTYEGKEDIIKLIYD------YIRKNILVNVENEMVKIKLT 113

Query: 117 KVATQGYEYKSSGITHQGENIYAIIQAPRGDATEAIVLVAAWKTIDGQLNLNGVSLALTL 176
               Q     + G  +              +  E++V+V  +   + +   + V + LTL
Sbjct: 114 DRIEQNILISNVGCKY-------------CNNMESLVVVINFDFKERKY-FHSVIIGLTL 159

Query: 177 ARYFKRWSLWSKDIIFVFPPDSK---SGTQAWVDAYHDMQPPTVQPLPLKSGALQGGLAI 233
             +F + +  SKD+ F+F         G Q ++  Y       +    ++S  +     I
Sbjct: 160 MEHFSKCNYMSKDVTFLFTNKELLYSLGVQEFIQKYFYNNTNRIGKKIIRSSTI-----I 214

Query: 234 EYPFDHRFENLHIIYDGVNGQLPNLDLFNTAVSIAGGQMGIGTRLQEMWDHNGSYEKRLQ 293
           E+        + I Y+G+NG LPN DL                 L            +++
Sbjct: 215 EFDS-IYPSYIKINYEGLNGMLPNQDLILL--------------LTNELHFYSIPI-KME 258

Query: 294 TMLRGMVKQGLGYA-AGAHSSFMPY---------------HIDAITLQT-----QGNGWQ 332
                +    L       H  F+ Y               +I A T          N   
Sbjct: 259 LTHGSIFDMALEKNYENGHIYFLRYKKKYEYIRDDNDEIKNIPAFTATGGSKVPIRNKMI 318

Query: 333 DEMALGRTVESLCRSLNNLLEHLHQSFFFYLLMQTHRFVSIGTYLPSAMLIAGNFTIM 390
           +   L + ++S  RS +N  E    S  FY      R + I  Y  S  LI     + 
Sbjct: 319 NLFNLTKALQSYLRSQSNTHEGFCHSSNFYFFNTFRRHIPISIYCYSVYLICAYSIMK 376
>ref|NP_197414.2| GPAA1 - like protein [Arabidopsis thaliana]
          Length = 699

 Score =  311 bits (791), Expect = 3e-83
 Identities = 78/400 (19%), Positives = 139/400 (34%), Gaps = 71/400 (17%)

Query: 263 TAVSIAGGQMGIGTRLQEMWD---HNGSYEKRLQTMLRGMVKQGLGYAAGAHSSFMPYHI 319
               I      +   L   W+       Y +   T+   +  Q LG   G H +F  Y +
Sbjct: 332 IFGEIFEAVGKLAHMLNPDWNFGIPAADYLEGSATLASSLYSQALGIPTGPHGAFRDYQV 391

Query: 320 DAITLQTQ------GNGWQDEMAL--GRTVESLCRSLNNLLEHLHQSFFFYLLMQTHRFV 371
           DAITL+            Q +  L   R +E   RS+NNLLE  HQSFF Y+L    +F+
Sbjct: 392 DAITLKVSPRFPPDSKTRQHDFFLRGARLLEGTIRSVNNLLEKFHQSFFLYMLTSPSKFI 451

Query: 372 SIGTYLPSAMLIAGNFTIMAIALWLRTGYYKDSTQAATVSARLVRDENITTSESEKAQLA 431
           S+G Y+ +  L+     ++A +L++                + + +     +E+ K+   
Sbjct: 452 SVGVYMIAFALLVAPLPMVAASLYI-------------DGCKSLTNSTHNPTENFKSWKW 498

Query: 432 SKDRNETAPTTGNPATKAAERQLALPLTLIIGLHLIGLIPLYIFNNISHDKYTL--ATYT 489
                +                       ++G  +  L   Y    +         +   
Sbjct: 499 LDAAKQVFTL------------------HLLGFIVTLLP--YFICQVPGQHSPTNRSIMW 538

Query: 490 SIAINAILPICLSFILSRITTP---TQISHQLHLIKSLSLLPLGLFLSTLATLNFSLSFM 546
               +++L I  +F+     +P           ++KS+++    + L  ++ +NF+ + +
Sbjct: 539 GTTSSSLLLI--TFVTMPGCSPFSSRLHGTNWAILKSVTISAAFIGLCLMSIINFATAEI 596

Query: 547 TGLLCTPLSFMH--IFDAKTKPFVRYTLSAFGMAFLNVISPPVVLLVG------------ 592
             LL  P   M   I  A     ++  L AF    L  I  PV+                
Sbjct: 597 GALLLVPTCLMAQPIKPALRSRRLKSLLGAFCSIVLLTIGFPVMFFAISKGLLGEGLVGL 656

Query: 593 -----FLTEAAFGWDVWGMWTQVVVWCVWWPAWVVGGVVL 627
                F T     W  W   T + +  V  P W++   +L
Sbjct: 657 SLGGEFWTWLESLW-AWKSATYLYIGMVHLPCWLLCLCIL 695
 Score =  234 bits (592), Expect = 6e-60
 Identities = 77/321 (23%), Positives = 130/321 (39%), Gaps = 44/321 (13%)

Query: 6   SLRNLRNNPYFLFVRLPYLLSFLCIVSGVIWLFLLPLDDYSRKTYISENALLPGQVHAYF 65
             R +     FL    P    F  + S    L LL L   ++ TYISENAL+PG   +  
Sbjct: 22  KPRPIVRLGIFLIAHSPV---FSVVFSAAGVLALLLLPLLAKNTYISENALMPGSARSML 78

Query: 66  AGSEQN--------------VFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQSIL 111
           +  + +                 G   E++ L+  + SD   + S ++      +   + 
Sbjct: 79  SNRDVSDGSKLVKDIKNFRLNHEGQGVEVQKLIGKYMSDMGAEVSYQKFHPEGNQFHPLH 138

Query: 112 MASGLKVATQGYEYKSSGITHQGENIYAIIQAPRGDATEAIVLVAAWKTID-GQLNLNGV 170
             SG    T     ++      G N+  II+APRGD  E+IVLV  +  I+ G      +
Sbjct: 139 FFSGPDSYT---LLENVSCASYGVNVAGIIRAPRGDGKESIVLVTPYDFINGGDYEDLSL 195

Query: 171 SLALTLARYFKRWSLWSKDIIFVFPPDSKSG----TQAWVDAYHDMQPPTVQPLPL---- 222
            +  +L     R +  SKDII++   DS+ G      AW+  YH    P+ +   L    
Sbjct: 196 GIVSSLFSLLSRVTWLSKDIIWLV-ADSRYGDYRPVAAWLTEYHS---PSFKVSDLLKCD 251

Query: 223 ---------KSGALQGGLAIEYP--FDHRFENLHIIYDGVNGQLPNLDLFNTAVSIAGGQ 271
                    ++G +   L ++     +   + L I  +  NGQ+PNLDL N    +A  +
Sbjct: 252 EQNTADNFRRAGTMAAALVLKVDGRSEKFEDTLSIYAEASNGQMPNLDLINVVNYLAVHR 311

Query: 272 MGIGTRLQEMWDHNGSYEKRL 292
            G   +++++     S   ++
Sbjct: 312 QGFYVKVEKVVSLLSSSWLKI 332
>gb|AAO00773.1| GPAA1 - like protein [Arabidopsis thaliana]
          Length = 699

 Score =  311 bits (791), Expect = 3e-83
 Identities = 76/382 (19%), Positives = 136/382 (34%), Gaps = 71/382 (18%)

Query: 281 MWD---HNGSYEKRLQTMLRGMVKQGLGYAAGAHSSFMPYHIDAITLQTQ------GNGW 331
            W+       Y +   T+   +  Q LG   G H +F  Y +DAITL+            
Sbjct: 350 DWNFGIPAADYLEGSATLASSLYSQALGIPTGPHGAFRDYQVDAITLKVSPRFPPDSKTR 409

Query: 332 QDEMAL--GRTVESLCRSLNNLLEHLHQSFFFYLLMQTHRFVSIGTYLPSAMLIAGNFTI 389
           Q +  L   R +E   RS+NNLLE  HQSFF Y+L    +F+S+G Y+ +  L+     +
Sbjct: 410 QHDFFLRGARLLEGTIRSVNNLLEKFHQSFFLYMLTSPSKFISVGVYMIAFALLVAPLPM 469

Query: 390 MAIALWLRTGYYKDSTQAATVSARLVRDENITTSESEKAQLASKDRNETAPTTGNPATKA 449
           +A +L++                + + +     +E+ K+        +            
Sbjct: 470 VAASLYI-------------DGCKSLTNSTHNPTENFKSWKWLDAAKQVFTL-------- 508

Query: 450 AERQLALPLTLIIGLHLIGLIPLYIFNNISHDKYTL--ATYTSIAINAILPICLSFILSR 507
                      ++G  +  L   Y    +         +       +++L I  +F+   
Sbjct: 509 ----------HLLGFIVTLLP--YFICQVPGQHSPTNRSIMWGTTSSSLLLI--TFVTMP 554

Query: 508 ITTP---TQISHQLHLIKSLSLLPLGLFLSTLATLNFSLSFMTGLLCTPLSFMH--IFDA 562
             +P           ++KS+++    + L  ++ +NF+ + +  LL  P   M   I  A
Sbjct: 555 GCSPFSSRLHGTNWAILKSVTISAAFIGLCLMSIINFATAEIGALLLVPTCLMAQPIKPA 614

Query: 563 KTKPFVRYTLSAFGMAFLNVISPPVVLLVG-----------------FLTEAAFGWDVWG 605
                ++  L AF    L  I  PV+                     F T     W  W 
Sbjct: 615 LRSRRLKSLLGAFCSIVLLTIGFPVMFFAISKGLLGEGLVGLSLGGEFWTWLESLW-AWK 673

Query: 606 MWTQVVVWCVWWPAWVVGGVVL 627
             T + +  V  P W++   +L
Sbjct: 674 SATYLYIGMVHLPCWLLCLCIL 695
 Score =  234 bits (592), Expect = 6e-60
 Identities = 77/321 (23%), Positives = 130/321 (39%), Gaps = 44/321 (13%)

Query: 6   SLRNLRNNPYFLFVRLPYLLSFLCIVSGVIWLFLLPLDDYSRKTYISENALLPGQVHAYF 65
             R +     FL    P    F  + S    L LL L   ++ TYISENAL+PG   +  
Sbjct: 22  KPRPIVRLGIFLIAHSPV---FSVVFSAAGVLALLLLPLLAKNTYISENALMPGSARSML 78

Query: 66  AGSEQN--------------VFRGYKKELEGLLDGHGSDGEKKKSEERTQVISEKIQSIL 111
           +  + +                 G   E++ L+  + SD   + S ++      +   + 
Sbjct: 79  SNRDVSDGSKLVKDIKNFRLNHEGQGVEVQKLIGKYMSDMGAEVSYQKFHPEGNQFHPLH 138

Query: 112 MASGLKVATQGYEYKSSGITHQGENIYAIIQAPRGDATEAIVLVAAWKTID-GQLNLNGV 170
             SG    T     ++      G N+  II+APRGD  E+IVLV  +  I+ G      +
Sbjct: 139 FFSGPDSYT---LLENVSCASYGVNVAGIIRAPRGDGKESIVLVTPYDFINGGDYEDLSL 195

Query: 171 SLALTLARYFKRWSLWSKDIIFVFPPDSKSG----TQAWVDAYHDMQPPTVQPLPL---- 222
            +  +L     R +  SKDII++   DS+ G      AW+  YH    P+ +   L    
Sbjct: 196 GIVSSLFSLLSRVTWLSKDIIWLV-ADSRYGDYRPVAAWLTEYHS---PSFKVSDLLKCD 251

Query: 223 ---------KSGALQGGLAIEYP--FDHRFENLHIIYDGVNGQLPNLDLFNTAVSIAGGQ 271
                    ++G +   L ++     +   + L I  +  NGQ+PNLDL N    +A  +
Sbjct: 252 EQNTADNFRRAGTMAAALVLKVDGRSEKFEDTLSIYAEASNGQMPNLDLINVVNYLAVHR 311

Query: 272 MGIGTRLQEMWDHNGSYEKRL 292
            G   +++++     S   ++
Sbjct: 312 QGFYVKVEKVVSLLSSSWLKI 332
>dbj|BAC81736.1| GPI transamidase component GAA1 [Trypanosoma brucei brucei]
          Length = 461

 Score =  278 bits (706), Expect = 3e-73
 Identities = 65/343 (18%), Positives = 108/343 (30%), Gaps = 44/343 (12%)

Query: 140 IIQAPRGDATEAIVLVAAWKTIDGQLNLNGVSLALTLARYFKRWSLWSKDIIFVFPPDSK 199
           +++  R   +E+I +               V LA  L    +     + D  F F  D  
Sbjct: 74  VVRGRRSVGSESIAVYVNAAF------EPSVVLANHLIYVLREKENMACDTNFYFFND-- 125

Query: 200 SGTQAWVDAYHDMQPPTVQPLPLKSGALQGGLAIEYPFDHRFENLHIIYDGVNGQLPNLD 259
                           T +  P+    ++  + I     H   NL     G NG  PN D
Sbjct: 126 ----------------TSKDWPIPDSFVRAAIVINVTSFHT-NNLCFNVFGANGMQPNQD 168

Query: 260 LFNTAVSIAGG-QMGIGTRLQE----MWDHNGSYEKR---LQTMLRGMVKQGLGYAAGAH 311
           LFN AV+IA   +  I    Q            YE     LQT L   ++    Y   + 
Sbjct: 169 LFNLAVAIAEKWRFNIDVLCQNPYISFSTSRPIYEHYFLALQTALVAPLRYQPWYKMRSR 228

Query: 312 S-SFMPYHIDAITLQTQGNGWQDEMALGRTVESLCRSLNNLLEHLHQSFFFYLLMQTHRF 370
             S +    +    +T+ +   +  A     E L  +L+ L E  H S   ++ +   ++
Sbjct: 229 GISLLAISTEKSERRTKSSYGYNMAA---AHEQLIATLSYLHERFHHSTSVWIPLSVDQY 285

Query: 371 VSIGTYLPSAMLIAGNFTIMAIALWLRTGYYKDSTQA---ATVSARLVRDENITTSESEK 427
           V       + +L   +      +++   G+      A   AT  A LV   N  T+    
Sbjct: 286 VEYDVIQFATILFVASLLSTCYSIYEVEGFSFSPCAALVSATGLAALVSTLNFGTAGFFV 345

Query: 428 AQLASKDRNETAPTTGNPATKAAERQLALPLTLIIGLHLIGLI 470
           +                           +   LII   + GL+
Sbjct: 346 SSGVLT----VGLGAFAWDMSWGAINAVVLCLLIILQPVAGLV 384
>emb|CAB86709.1| hypothetical protein L3640.14 [Leishmania major]
          Length = 464

 Score =  265 bits (673), Expect = 2e-69
 Identities = 54/349 (15%), Positives = 93/349 (26%), Gaps = 56/349 (16%)

Query: 141 IQAPRGDATEAIVLVAAWKTIDGQLNLNGVSLALTLARYFKRWSLWSKDIIFVFPPDSKS 200
           ++  R   +E   +               VSLA  L    +R    + D+ F F   S  
Sbjct: 74  VRGRRSPGSEIAAVYVNTDYP------ASVSLANALIEVIRRRKSLACDVQFYFVNSS-- 125

Query: 201 GTQAWVDAYHDMQPPTVQPLPLKSGALQGGLAIEYPFDHRFENLHIIYDGVNGQLPNLDL 260
                            +  P+     +  L +         ++ I   G NG  PN D 
Sbjct: 126 -----------------EEWPVPQAYTRAALVLNL-STLYNRHICIDTLGGNGIQPNQDY 167

Query: 261 FNTAVSIAGGQMGIGTRLQEMWDHNGS--------YEKRLQTMLRGMVKQGLGYAAGAHS 312
            N AV +A     + + L +    +          Y   L+  ++   +    +    HS
Sbjct: 168 TNIAVQLAAANQFLPSYLCQRRHRSTDDAHAGFWHYWAYLEASVQLPTRPQPWHIIPTHS 227

Query: 313 SFMPYHIDAITLQTQGNGWQDEM----------ALGRTVESLCRSLNNLLEHLHQSFFFY 362
                     T+    +                A  + V  +  SLN L E  H S F +
Sbjct: 228 I--------NTIAISSDPLYSASSVFPHSQLPDAFAQLVLKIIVSLNGLEEKFHHSTFVW 279

Query: 363 LLMQTHRFVSIGTYLPSAMLIAGNFTIMAIALWLRTGYYKDSTQAATVSARLVRDENITT 422
           L +   R+V         +L   +      + +   G          +   +        
Sbjct: 280 LPVSLWRYVEYDHAQFCIILFVASIFSTTYSEYQLRGISITPLFVTLLLTPVAAAAAFQV 339

Query: 423 SESEKAQLASKDRNETAPTTGNPATKAAERQLALPLTLIIGLHLIGLIP 471
           +       A    +             A   + L    I    LI L P
Sbjct: 340 AG----WWAVVSASAAFSLLFRLLMGHANSGMLLSFNAIALCLLIILQP 384
>ref|XP_290985.3| similar to LIM and senescent cell antigen-like domains 1 [Homo
           sapiens]
          Length = 883

 Score =  245 bits (620), Expect = 3e-63
 Identities = 62/287 (21%), Positives = 103/287 (35%), Gaps = 37/287 (12%)

Query: 263 TAVSIAGGQMGIGTRLQ-EMWDHNGSYEKRLQTMLRGMVKQGLGYAAGAHSSFMPYHIDA 321
           T     G    +  +LQ + W       + LQT+L  ++ Q           F+ YH++A
Sbjct: 590 TFCQKVGLLCTLQGKLQPQDWTLLDELLQGLQTLLLMILWQAS------RGLFLHYHVEA 643

Query: 322 ITLQTQGNGWQ---DEMALGRTVESLCRSLNNLLEHLHQSFFFYLLMQTHRFVSIGTYLP 378
           +TL+   +  Q   D +A G+ +E +   LN+LLEH HQ FF YLL    RFVSIG Y+P
Sbjct: 644 LTLRRISSFRQYKYDLVAAGKALEGMFCKLNHLLEHPHQLFFLYLLPTLSRFVSIGLYMP 703

Query: 379 SAMLIAGNFTIMAIALWLRTGYYKDSTQAATVSARLVRDENITTSESEKAQLASKDRNET 438
           +   +       A+ LW++                   +  +   E       S    + 
Sbjct: 704 ATSFLLLVLGFKALQLWMQL-----------------HEAGVGLEELRGVPDPSVPLPQH 746

Query: 439 APT-TGNPATKAAERQLALPLTLI--IGLHLIG------LIPLYIFNNISHDKYTLATYT 489
               T  P       +L   + LI  +G   +       L+   +   +    +   T  
Sbjct: 747 RMVSTQVPDRGWMALKLVALIYLILQLGCIALTNFXLDFLLAATMVLPLCRRAFGPWTLC 806

Query: 490 SIAINAILPICLSFILSRITTPTQISHQLHLIKSLSLLPLGLFLSTL 536
           ++ +  +     + + S           L L K   L    L    L
Sbjct: 807 AV-LLVLTSPAATLLGSPFLWRELQEAPLSLAKGWQLFLAALAQGAL 852
 Score =  103 bits (257), Expect = 1e-20
 Identities = 21/98 (21%), Positives = 32/98 (32%), Gaps = 15/98 (15%)

Query: 507 RITTPTQISHQ-----LHLIKSLSLLPLGLFLSTLATLNFSLSFMTGLLCTPLSFMHIFD 561
            +     +S Q        +K ++L+ L L L  +A  NF L F+               
Sbjct: 742 PLPQHRMVSTQVPDRGWMALKLVALIYLILQLGCIALTNFXLDFLLAATMV-------LP 794

Query: 562 AKTKPFVRYTLSAFGMAFLNVISPPVVLLVGFLTEAAF 599
              + F  +TL A     L + SP   LL         
Sbjct: 795 LCRRAFGPWTLCAV---LLVLTSPAATLLGSPFLWREL 829
>ref|NP_491701.1| gaa1-like, GPI transamidase component (1G434) [Caenorhabditis
           elegans]
 pir||T32772 hypothetical protein F33D11.9a - Caenorhabditis elegans
 gb|AAB96702.1| Hypothetical protein F33D11.9a [Caenorhabditis elegans]
          Length = 229

 Score =  152 bits (383), Expect = 2e-35
 Identities = 32/234 (13%), Positives = 65/234 (27%), Gaps = 56/234 (23%)

Query: 375 TYLPSAMLIAGNFTIMAIALWLRTGYYKDSTQAATVSARLVRDENITTSESEKAQLASKD 434
            Y+    ++     I A   W +   ++           +V              +A+  
Sbjct: 1   MYIIPLTILVSPLVISAYFEWTKIQEFQFP---------VVHLAFHVL--GFFYYIATTY 49

Query: 435 RNETAPTTGNPATKAAERQLALPLTLIIGLHLIGLIPLYIFNNISHDKYTLATYTSIAIN 494
             +T  TT        +               +G+            ++T +     +  
Sbjct: 50  VFQTIGTTFVLQ--WMQWP------------FVGIDG-------CDGQFTPSWSLINSFL 88

Query: 495 AILPICLSFILSRITTPTQISHQLHLIKSLSLLPLGLFLSTLATLN--FSLSFMTGLLCT 552
               I L                   +K+ S+       S LA LN    L+F+   +  
Sbjct: 89  IFFMIPL--------------GPYVFLKTRSIFRS----SVLAILNPISVLAFV--AINI 128

Query: 553 PLSFMHIFDAKTKPFVRYTLSAFGMAFLNVISPPVVLLVGFLTEAAFGWDVWGM 606
           P  F  +F   ++    +  +A  +A   +       +  F     FG+ +W M
Sbjct: 129 PGMFGQLFPTISQD--SWLAAAQSIALTAIREDVEFKVNHFFLLCCFGYPIWNM 180
CPU time:   286.34 user secs.	    4.79 sys. secs	  291.13 total secs.

  Database: nr
    Posted date:  Nov 22, 2003  1:30 PM
  Number of letters in database: 504,497,942
  Number of sequences in database:  1,543,518
  
Lambda     K      H
   0.315    0.174    0.477 

Gapped
Lambda     K      H
   0.270   0.0612    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 772797812
Number of Sequences: 1543518
Number of extensions: 41572036
Number of successful extensions: 128638
Number of sequences better than 10.0: 866
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 847
Number of HSP's that attempted gapping in prelim test: 127978
Number of HSP's gapped (non-prelim): 1209
length of query: 633
length of database: 504,497,942
effective HSP length: 57
effective length of query: 576
effective length of database: 416,517,416
effective search space: 239914031616
effective search space used: 239914031616
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.2 bits)
S2: 79 (34.8 bits)