Figure 1. TGF-beta: structure, latency, activation, and receptors LAP indicates latency-associated peptide; LTBP, latent TGF-beta binding protein; M6P/IGFII-R, mannose-6-phosphate/type II insulin-like growth factor receptor; PLg, plasminogen; PL, plasmin; Smad, TGF-beta signal transduction proteins; Anti-Smad, antagonistic Smad; Co-Smad, common-partner Smad; R-Smad, receptor-regulated Smad; TGase, transglutaminase; TbetaR-I, -II, -III, TGF-beta receptor type I, II, III; TSP, thrombospondin; uPA, urokinase plasminogen activator; and uPA-R, uPA receptor.

PubMed:10979943

Transforming growth factor-beta: pleiotropic role in the regulation of hematopoiesis. Fortunel NO, Hatzfeld A, Hatzfeld JA. Blood. 2000 Sep 15;96(6):2022-36. Review.