Legend:
Sequences with E-value BETTER than threshold 298 3e-80
298 3e-80
288 3e-77
285 2e-76
256 1e-67
250 6e-66
234 4e-61
234 4e-61
230 8e-60
229 2e-59
229 2e-59
229 2e-59
228 3e-59
228 3e-59
227 5e-59
227 6e-59
227 7e-59
226 1e-58
226 1e-58
226 1e-58
226 1e-58
226 2e-58
226 2e-58
226 2e-58
226 2e-58
226 2e-58
226 2e-58
225 3e-58
225 3e-58
224 4e-58
224 4e-58
224 5e-58
224 5e-58
222 1e-57
222 3e-57
222 3e-57
220 1e-56
219 1e-56
215 3e-55
213 1e-54
209 1e-53
209 2e-53
208 3e-53
208 3e-53
208 3e-53
207 5e-53
206 9e-53
204 4e-52
202 3e-51
197 4e-50
Alignments
>ref|XP_008288.1| KIAA0672 gene product [Homo sapiens]
Length = 818
Score = 298 bits (757), Expect = 3e-80
Identities = 180/180 (100%), Positives = 180/180 (100%)
Query: 1 PSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCV 60
PSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCV
Sbjct: 251 PSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCV 310
Query: 61 VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL 120
VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL
Sbjct: 311 VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL 370
Query: 121 PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQI 180
PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQI
Sbjct: 371 PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQI 430
>ref|NP_055674.1| KIAA0672 gene product [Homo sapiens]
dbj|BAA31647.1| (AB014572) KIAA0672 protein [Homo sapiens]
Length = 818
Score = 298 bits (756), Expect = 3e-80
Identities = 180/180 (100%), Positives = 180/180 (100%)
Query: 1 PSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCV 60
PSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCV
Sbjct: 251 PSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCV 310
Query: 61 VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL 120
VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL
Sbjct: 311 VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL 370
Query: 121 PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQI 180
PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQI
Sbjct: 371 PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQI 430
>dbj|BAB14506.1| (AK023281) unnamed protein product [Homo sapiens]
Length = 726
Score = 288 bits (732), Expect = 3e-77
Identities = 121/180 (67%), Positives = 142/180 (78%)
Query: 1 PSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCV 60
P+FG PL EHL SGREIA PIEACV +LLE GM+EEGLFR+ ASKLKKLKAALDC
Sbjct: 171 PAFGTPLAEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCST 230
Query: 61 VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL 120
+ E+ +DPHA+AGALKSYLRELPEPLMTF LY+EW Q ++VQ+QDKKLQ LW C+KL
Sbjct: 231 SHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKL 290
Query: 121 PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQI 180
P N N RYLIKFL+KL++ DVNKMTPSN+AIVLGPNLLW + EG + EM S+ +
Sbjct: 291 PPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATSVHV 350
>ref|NP_071580.1| nadrin; neuron-specific GTPase activating protein [Rattus
norvegicus]
dbj|BAB12426.1| (AB042827) Nadrin [Rattus norvegicus]
Length = 780
Score = 285 bits (724), Expect = 2e-76
Identities = 121/180 (67%), Positives = 143/180 (79%)
Query: 1 PSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCV 60
P+FG PLEEHL SGREIA PIEACV +LLE GM+EEGLFR+ ASKLKKLKAALDC
Sbjct: 248 PAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCST 307
Query: 61 VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL 120
+ E+ +DPHA+AGALKSYLRELPEPLMTF LY+EW Q ++VQ+QDKKLQ LW C+KL
Sbjct: 308 SHLDEFYSDPHAVAGALKSYLRELPEPLMTFSLYEEWTQVASVQDQDKKLQYLWTTCQKL 367
Query: 121 PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQI 180
P N N RYLIKFL+KL++ DVNKMTPSN+AIVLGPNLLW + EG + E+ S+ +
Sbjct: 368 PPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWAKQEGTLAEIAAATSVHV 427
>ref|NP_061830.1| SH3-domain binding protein 1 [Homo sapiens]
emb|CAB42896.1| (Z83844) dJ37E16.2 (SH3-domain binding protein 1) [Homo sapiens]
Length = 616
Score = 256 bits (649), Expect = 1e-67
Identities = 103/183 (56%), Positives = 137/183 (74%), Gaps = 4/183 (2%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEE-GLFRVAPSASKLKKLKAALDCCV 60
+G L HL GREIA PIEACV MLL GM+EE GLFR+A AS LK+LK +
Sbjct: 193 VYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEVGLFRLAAGASVLKRLKQTMASDP 252
Query: 61 VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL 120
++E+ +DPHA+AGALKSYLRELPEPLMTF+LYD+W++A++++E +LQAL C +L
Sbjct: 253 HSLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSRL 312
Query: 121 PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLW-PQAEGNITEMMTT--VS 177
P N +N+RYL+KFL++L+E Q+VNKMTPSN+AIVLGPNLLW P+ EG+ ++ S
Sbjct: 313 PPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVSS 372
Query: 178 LQI 180
+Q+
Sbjct: 373 IQV 375
>ref|NP_033190.1| SH3-domain binding protein 1 [Mus musculus]
sp|P55194|3BP1_MOUSE SH3-BINDING PROTEIN 3BP-1
pir||S56144 SH3 domain binding protein - mouse
emb|CAA61011.1| (X87671) SH3 domain binding protein [Mus musculus]
Length = 601
Score = 250 bits (635), Expect = 6e-66
Identities = 101/183 (55%), Positives = 136/183 (74%), Gaps = 4/183 (2%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQ-EEGLFRVAPSASKLKKLKAALDCCV 60
+G L HL GR+IA PIEACV +LL GMQ EEGLFR+A AS LK+LK +
Sbjct: 193 VYGVSLRTHLQDLGRDIALPIEACVLLLLSEGMQEEEGLFRLAAGASVLKRLKQTMASDP 252
Query: 61 VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL 120
++E+ + PHA+AGALKSYLRELPEPLMT +LYD+W++A++++E +L+AL + C +L
Sbjct: 253 HSLEEFCSGPHAVAGALKSYLRELPEPLMTSDLYDDWMRAASLKEPGARLEALHDVCSRL 312
Query: 121 PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLW-PQAEGNITEMMTT--VS 177
P+ N NN+RYL+KFL+ L+E QDVNKMTPSN+AIVLGPNLLW P+ EG+ ++ S
Sbjct: 313 PQENFNNLRYLMKFLALLAEEQDVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVSS 372
Query: 178 LQI 180
+Q+
Sbjct: 373 IQV 375
>gb|AAB82943.1| (AF029913) GTPase activating protein homolog [Cochliobolus
heterostrophus]
Length = 714
Score = 234 bits (594), Expect = 4e-61
Identities = 46/171 (26%), Positives = 95/171 (54%), Gaps = 5/171 (2%)
Query: 1 PSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCV 60
P FG LEE G + + C+ + G++ EG++R+ ++S ++++KA +
Sbjct: 527 PIFGVTLEELFRRDGSPVPIIVYQCIQAVDLYGLEVEGIYRIPGTSSHIQQMKA-----L 581
Query: 61 VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL 120
D + + D +++AG LK + RELP+PL+T E Y ++I+A+ + + + ++ L
Sbjct: 582 FDSESFQHDVNSVAGLLKQFFRELPDPLLTREFYGKYIEAARIDDDTMRRDSMHALINAL 641
Query: 121 PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITE 171
P N+ +R L L ++ + ++N+M+ +N+AI P+++ P N+ +
Sbjct: 642 PDPNYATLRALALHLHRVQQSSEINRMSTANLAICWAPSIMGPHKGNNMAD 692
>gb|AAB84002.1| (AF027687) GTPase activating protein homolog [Cochliobolus
heterostrophus]
Length = 714
Score = 234 bits (594), Expect = 4e-61
Identities = 46/171 (26%), Positives = 95/171 (54%), Gaps = 5/171 (2%)
Query: 1 PSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCV 60
P FG LEE G + + C+ + G++ EG++R+ ++S ++++KA +
Sbjct: 527 PIFGVTLEELFRRDGSPVPIIVYQCIQAVDLYGLEVEGIYRIPGTSSHIQQMKA-----L 581
Query: 61 VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL 120
D + + D +++AG LK + RELP+PL+T E Y ++I+A+ + + + ++ L
Sbjct: 582 FDSESFQHDVNSVAGLLKQFFRELPDPLLTREFYGKYIEAARIDDDTMRRDSMHALINAL 641
Query: 121 PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITE 171
P N+ +R L L ++ + ++N+M+ +N+AI P+++ P N+ +
Sbjct: 642 PDPNYATLRALALHLHRVQQSSEINRMSTANLAICWAPSIMGPHKGNNMAD 692
>gb|AAF55715.1| (AE003728) CG4755 gene product [Drosophila melanogaster]
Length = 740
Score = 230 bits (582), Expect = 8e-60
Identities = 71/166 (42%), Positives = 108/166 (64%), Gaps = 2/166 (1%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 62
FG L+EHLT + REI++ +E C LLE G++EEGL RV +++KL+++K AL+ V
Sbjct: 249 FGTSLKEHLTSTNREISYIVELCCCCLLEHGLEEEGLLRVGCASTKLRRMKHALEAQHVK 308
Query: 63 --VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL 120
+ DPH I LK YLRELPEPL+T+ LY ++I+ + + ++ + KL
Sbjct: 309 TPLPLDYQDPHVIGSILKLYLRELPEPLLTYNLYKDFIRIAERHSEAERKTEIKAILTKL 368
Query: 121 PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAE 166
PK N+ N+RYL +FLS + + +NKM+ N+AIV+ PN+LWP+ +
Sbjct: 369 PKENYANLRYLTRFLSIVQQRSALNKMSSQNLAIVMSPNMLWPRID 414
>ref|NP_067585.1| breakpoint cluster region, isoform 2 [Homo sapiens]
emb|CAA68676.1| (Y00661) bcr polypeptide [Homo sapiens]
Length = 1227
Score = 229 bits (580), Expect = 2e-59
Identities = 57/164 (34%), Positives = 86/164 (51%), Gaps = 2/164 (1%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVV 61
FG + ++ + + CV + GM+E G++RV+ A+ ++ LKAA D
Sbjct: 1007 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 1066
Query: 62 DVQEYSA--DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEK 119
DV + D +AIAG LK Y RELPEPL T E Y + + + + K + N
Sbjct: 1067 DVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLS 1126
Query: 120 LPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP 163
LP+AN +L+ L +++E + VNKM+ N+A V GP LL P
Sbjct: 1127 LPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRP 1170
>ref|XP_009870.1| breakpoint cluster region, isoform 1 [Homo sapiens]
gb|AAB60388.1| (U07000) breakpoint cluster region protein [Homo sapiens]
Length = 1271
Score = 229 bits (579), Expect = 2e-59
Identities = 57/164 (34%), Positives = 86/164 (51%), Gaps = 2/164 (1%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVV 61
FG + ++ + + CV + GM+E G++RV+ A+ ++ LKAA D
Sbjct: 1051 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 1110
Query: 62 DVQEYSA--DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEK 119
DV + D +AIAG LK Y RELPEPL T E Y + + + + K + N
Sbjct: 1111 DVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLS 1170
Query: 120 LPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP 163
LP+AN +L+ L +++E + VNKM+ N+A V GP LL P
Sbjct: 1171 LPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRP 1214
>ref|NP_004318.2| breakpoint cluster region, isoform 1 [Homo sapiens]
sp|P11274|BCR_HUMAN BREAKPOINT CLUSTER REGION PROTEIN
pir||TVHUBR bcr (breakpoint cluster region) protein, splice form 1 - human
emb|CAA26441.1| (X02596) bcr [Homo sapiens]
Length = 1271
Score = 229 bits (579), Expect = 2e-59
Identities = 57/164 (34%), Positives = 86/164 (51%), Gaps = 2/164 (1%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVV 61
FG + ++ + + CV + GM+E G++RV+ A+ ++ LKAA D
Sbjct: 1051 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 1110
Query: 62 DVQEYSA--DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEK 119
DV + D +AIAG LK Y RELPEPL T E Y + + + + K + N
Sbjct: 1111 DVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLS 1170
Query: 120 LPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP 163
LP+AN +L+ L +++E + VNKM+ N+A V GP LL P
Sbjct: 1171 LPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRP 1214
>gb|AAF80386.1|AF159851_1 (AF159851) Rho GAP p190-A [Homo sapiens]
Length = 1514
Score = 228 bits (577), Expect = 3e-59
Identities = 53/162 (32%), Positives = 91/162 (55%), Gaps = 2/162 (1%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCC-VV 61
FG PL +T I IE C+ + G+ EG++RV+ + S+++ L+ D +
Sbjct: 1248 FGVPLTTVVTPEK-PIPIFIERCIEYIEATGLSTEGIYRVSGNKSEIESLQRQFDQDHNL 1306
Query: 62 DVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLP 121
D+ E + +AGA+KS+ ELP+PL+ + + + ++A + ++++KL AL +K P
Sbjct: 1307 DLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFP 1366
Query: 122 KANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP 163
K NH +Y+I L+K+S VN MT N++I P L+ P
Sbjct: 1367 KENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRP 1408
>pir||T46354 hypothetical protein DKFZp434F1016.1 - human (fragment)
emb|CAB70679.1| (AL137287) hypothetical protein [Homo sapiens]
Length = 1397
Score = 228 bits (577), Expect = 3e-59
Identities = 52/175 (29%), Positives = 97/175 (54%), Gaps = 1/175 (0%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 62
FG L LT R + +E + + G+ EG++R + S +K+K+L+ LD
Sbjct: 910 FGVELSR-LTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAES 968
Query: 63 VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPK 122
V + H IA K +LR+LP PLMTFELY+E+++A +QE+ + ++ +++ ++L +
Sbjct: 969 VNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSR 1028
Query: 123 ANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVS 177
+ N + LI L +++ +D N+M+ + +AIV P +L + + + +S
Sbjct: 1029 THLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDIS 1083
>dbj|BAA91979.1| (AK001923) unnamed protein product [Homo sapiens]
Length = 526
Score = 227 bits (576), Expect = 5e-59
Identities = 52/175 (29%), Positives = 97/175 (54%), Gaps = 1/175 (0%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 62
FG L LT R + +E + + G+ EG++R + S +K+K+L+ LD
Sbjct: 39 FGVELSR-LTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAES 97
Query: 63 VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPK 122
V + H IA K +LR+LP PLMTFELY+E+++A +QE+ + ++ +++ ++L +
Sbjct: 98 VNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSR 157
Query: 123 ANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVS 177
+ N + LI L +++ +D N+M+ + +AIV P +L + + + +S
Sbjct: 158 THLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDIS 212
>ref|NP_008832.1| myosin IXA [Homo sapiens]
gb|AAD49195.1|AF117888_1 (AF117888) myosin-IXa [Homo sapiens]
Length = 2548
Score = 227 bits (575), Expect = 6e-59
Identities = 52/175 (29%), Positives = 97/175 (54%), Gaps = 1/175 (0%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 62
FG L LT R + +E + + G+ EG++R + S +K+K+L+ LD
Sbjct: 2061 FGVELSR-LTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAES 2119
Query: 63 VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPK 122
V + H IA K +LR+LP PLMTFELY+E+++A +QE+ + ++ +++ ++L +
Sbjct: 2120 VNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSR 2179
Query: 123 ANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVS 177
+ N + LI L +++ +D N+M+ + +AIV P +L + + + +S
Sbjct: 2180 THLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDIS 2234
>ref|NP_004136.1| myosin IXB [Homo sapiens]
pir||A59256 myosin-IXb [similarity] - human
gb|AAC50402.1| (U42391) myosin-IXb [Homo sapiens]
Length = 2022
Score = 227 bits (575), Expect = 7e-59
Identities = 61/171 (35%), Positives = 100/171 (57%), Gaps = 2/171 (1%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 62
FG ++ LT + +E + + G+ EGL+R + +A++ ++L+ AL
Sbjct: 1698 FGVCVD-SLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAA 1756
Query: 63 VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPK 122
V+ + HAI G LK +LRELPEPLMTF Y ++++A + E+ ++L A++ E LP+
Sbjct: 1757 VKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPE 1816
Query: 123 ANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLW-PQAEGNITEM 172
ANHN++ LI L K++ +DVN+M+P +AI+ P LL P +T M
Sbjct: 1817 ANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSM 1867
>gb|AAA18934.1| (U02289) GTPase-activating protein [Caenorhabditis elegans]
Length = 1439
Score = 226 bits (573), Expect = 1e-58
Identities = 57/189 (30%), Positives = 106/189 (55%), Gaps = 11/189 (5%)
Query: 1 PSFGKPLEEHLTISGRE-IAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCC 59
P G + + T S + + ++ACV ++ GM G++R+ + + + LK +L
Sbjct: 778 PVLGVRIADCPTGSCEDHVPMIVQACVCVIETYGMDTVGIYRIPGNTAAVNALKESLSNR 837
Query: 60 VVDVQEYSA---------DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKL 110
D + S D + ++ LK +LR+LPEPL+T +LY +I A+ + +L
Sbjct: 838 GFDSVDLSKVESLDPRWRDVNVVSSLLKMFLRKLPEPLLTDKLYPFFIDANRISTHHNRL 897
Query: 111 QALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNIT 170
L N KLP+ +++ +R+LI LS+++++ DVNKM N+A++ GP+++ P ++ N+
Sbjct: 898 HKLRNLLRKLPRPHYDTLRFLIVHLSEITKHSDVNKMECRNLALMFGPSIVRP-SDDNMA 956
Query: 171 EMMTTVSLQ 179
M+T +S Q
Sbjct: 957 TMVTHMSDQ 965
>dbj|BAA86518.1| (AB033030) KIAA1204 protein [Homo sapiens]
Length = 1445
Score = 226 bits (573), Expect = 1e-58
Identities = 46/164 (28%), Positives = 93/164 (56%), Gaps = 4/164 (2%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAAL---DC 58
+FG L E+L SG+++ + +++C + G+ +G++R++ S +++L+ C
Sbjct: 19 AFGCDLTEYLESSGQDVPYVLKSCAEFIETHGI-VDGIYRLSGVTSNIQRLRQEFGSDQC 77
Query: 59 CVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACE 118
+ + Y D H + K Y RELP PL+T+ELY+++ +A + ++ +L + N +
Sbjct: 78 PDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLARIQNVIQ 137
Query: 119 KLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLW 162
+LP +++ + YLI+ L+ ++ + M N+A+V PNLL
Sbjct: 138 ELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLR 181
>ref|XP_009038.1| glucocorticoid receptor DNA binding factor 1 [Homo sapiens]
Length = 1074
Score = 226 bits (572), Expect = 1e-58
Identities = 53/162 (32%), Positives = 91/162 (55%), Gaps = 2/162 (1%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCC-VV 61
FG PL +T I IE C+ + G+ EG++RV+ + S+++ L+ D +
Sbjct: 871 FGVPLTTVVTPEK-PIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNL 929
Query: 62 DVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLP 121
D+ E + +AGA+KS+ ELP+PL+ + + + ++A + ++++KL AL +K P
Sbjct: 930 DLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFP 989
Query: 122 KANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP 163
K NH +Y+I L+K+S VN MT N++I P L+ P
Sbjct: 990 KENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRP 1031
>pir||T31099 myosin-RhoGAP protein, Myr 7 - rat
emb|CAA04946.1| (AJ001713) myosin-RhoGAP protein, Myr 7 [Rattus norvegicus]
Length = 2626
Score = 226 bits (572), Expect = 1e-58
Identities = 51/175 (29%), Positives = 97/175 (55%), Gaps = 1/175 (0%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 62
FG L LT R + +E + + G+ EG++R + S +K+K+L+ LD
Sbjct: 2129 FGVELSR-LTSEDRAVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAES 2187
Query: 63 VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPK 122
V + H IA K +LR+LP PLMTFELY+E+++A +QE+ + ++ +++ ++L +
Sbjct: 2188 VNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSR 2247
Query: 123 ANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVS 177
+ + + LI L +++ +D N+M+ + +AIV P +L + + + +S
Sbjct: 2248 THLSTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDIS 2302
>ref|XP_008854.1| myosin IXB [Homo sapiens]
Length = 1713
Score = 226 bits (571), Expect = 2e-58
Identities = 61/171 (35%), Positives = 100/171 (57%), Gaps = 2/171 (1%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 62
FG ++ LT + +E + + G+ EGL+R + +A++ ++L+ AL
Sbjct: 1482 FGVCVD-SLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAA 1540
Query: 63 VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPK 122
V+ + HAI G LK +LRELPEPLMTF Y ++++A + E+ ++L A++ E LP+
Sbjct: 1541 VKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPE 1600
Query: 123 ANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLW-PQAEGNITEM 172
ANHN++ LI L K++ +DVN+M+P +AI+ P LL P +T M
Sbjct: 1601 ANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSM 1651
>gb|AAB60390.1| (U07000) breakpoint cluster region protein [Homo sapiens]
Length = 936
Score = 226 bits (571), Expect = 2e-58
Identities = 57/164 (34%), Positives = 86/164 (51%), Gaps = 2/164 (1%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVV 61
FG + ++ + + CV + GM+E G++RV+ A+ ++ LKAA D
Sbjct: 716 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 775
Query: 62 DVQEYSA--DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEK 119
DV + D +AIAG LK Y RELPEPL T E Y + + + + K + N
Sbjct: 776 DVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLS 835
Query: 120 LPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP 163
LP+AN +L+ L +++E + VNKM+ N+A V GP LL P
Sbjct: 836 LPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRP 879
>gb|AAF53844.1| (AE003664) CdGAPr gene product [Drosophila melanogaster]
Length = 1817
Score = 226 bits (571), Expect = 2e-58
Identities = 59/169 (34%), Positives = 95/169 (55%), Gaps = 6/169 (3%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALD-CCV 60
F L EHL SG++I + +C + G+ +G++R++ S +++L+ A D V
Sbjct: 421 VFNCDLSEHLLNSGQDIPMVLRSCAEFIENYGVI-DGIYRLSGITSNIQRLRRAFDEERV 479
Query: 61 VDV--QEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNV--QEQDKKLQALWNA 116
D+ E D HA++ LK Y RELP PL T++LYD +++A V E D++L+ +
Sbjct: 480 PDLGNPEMKQDIHAVSSLLKMYFRELPNPLCTYQLYDNFVEAIQVKADEADERLRLMKET 539
Query: 117 CEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQA 165
KLP ++ ++YL + L K+S++ MT N+AIV PNLL A
Sbjct: 540 VLKLPPPHYRTLKYLAEHLYKVSQHHGRTGMTDKNLAIVWAPNLLRSPA 588
>gb|AAF44627.1| (AF218776) GTPase activating protein [Drosophila melanogaster]
Length = 1843
Score = 226 bits (571), Expect = 2e-58
Identities = 59/169 (34%), Positives = 95/169 (55%), Gaps = 6/169 (3%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALD-CCV 60
F L EHL SG++I + +C + G+ +G++R++ S +++L+ A D V
Sbjct: 421 VFNCDLSEHLLNSGQDIPMVLRSCAEFIENYGVI-DGIYRLSGITSNIQRLRRAFDEERV 479
Query: 61 VDV--QEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNV--QEQDKKLQALWNA 116
D+ E D HA++ LK Y RELP PL T++LYD +++A V E D++L+ +
Sbjct: 480 PDLGNPEMKQDIHAVSSLLKMYFRELPNPLCTYQLYDNFVEAIQVKADEADERLRLMKET 539
Query: 117 CEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQA 165
KLP ++ ++YL + L K+S++ MT N+AIV PNLL A
Sbjct: 540 VLKLPPPHYRTLKYLAEHLYKVSQHHGRTGMTDKNLAIVWAPNLLRSPA 588
>sp|P34588|YN54_CAEEL HYPOTHETICAL 80.8 KD PROTEIN ZC21.4 IN CHROMOSOME III
Length = 747
Score = 226 bits (571), Expect = 2e-58
Identities = 57/189 (30%), Positives = 106/189 (55%), Gaps = 11/189 (5%)
Query: 1 PSFGKPLEEHLTISGRE-IAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCC 59
P G + + T S + + ++ACV ++ GM G++R+ + + + LK +L
Sbjct: 86 PVLGVRIADCPTGSCEDHVPMIVQACVCVIETYGMDTVGIYRIPGNTAAVNALKESLSNR 145
Query: 60 VVDVQEYSA---------DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKL 110
D + S D + ++ LK +LR+LPEPL+T +LY +I A+ + +L
Sbjct: 146 GFDSVDLSKVESLDPRWRDVNVVSSLLKMFLRKLPEPLLTDKLYPFFIDANRISTHHNRL 205
Query: 111 QALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNIT 170
L N KLP+ +++ +R+LI LS+++++ DVNKM N+A++ GP+++ P ++ N+
Sbjct: 206 HKLRNLLRKLPRPHYDTLRFLIVHLSEITKHSDVNKMECRNLALMFGPSIVRP-SDDNMA 264
Query: 171 EMMTTVSLQ 179
M+T +S Q
Sbjct: 265 TMVTHMSDQ 273
>pir||S44876 ZC21.4 protein - Caenorhabditis elegans
gb|AAA28171.1| (L16685) homology with breakpoint cluster region protein; putative
[Caenorhabditis elegans]
Length = 733
Score = 226 bits (571), Expect = 2e-58
Identities = 57/189 (30%), Positives = 106/189 (55%), Gaps = 11/189 (5%)
Query: 1 PSFGKPLEEHLTISGRE-IAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCC 59
P G + + T S + + ++ACV ++ GM G++R+ + + + LK +L
Sbjct: 72 PVLGVRIADCPTGSCEDHVPMIVQACVCVIETYGMDTVGIYRIPGNTAAVNALKESLSNR 131
Query: 60 VVDVQEYSA---------DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKL 110
D + S D + ++ LK +LR+LPEPL+T +LY +I A+ + +L
Sbjct: 132 GFDSVDLSKVESLDPRWRDVNVVSSLLKMFLRKLPEPLLTDKLYPFFIDANRISTHHNRL 191
Query: 111 QALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNIT 170
L N KLP+ +++ +R+LI LS+++++ DVNKM N+A++ GP+++ P ++ N+
Sbjct: 192 HKLRNLLRKLPRPHYDTLRFLIVHLSEITKHSDVNKMECRNLALMFGPSIVRP-SDDNMA 250
Query: 171 EMMTTVSLQ 179
M+T +S Q
Sbjct: 251 TMVTHMSDQ 259
>gb|AAB60389.1| (U07000) breakpoint cluster region protein [Homo sapiens]
Length = 889
Score = 225 bits (570), Expect = 3e-58
Identities = 57/164 (34%), Positives = 86/164 (51%), Gaps = 2/164 (1%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVV 61
FG + ++ + + CV + GM+E G++RV+ A+ ++ LKAA D
Sbjct: 669 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 728
Query: 62 DVQEYSA--DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEK 119
DV + D +AIAG LK Y RELPEPL T E Y + + + + K + N
Sbjct: 729 DVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLS 788
Query: 120 LPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP 163
LP+AN +L+ L +++E + VNKM+ N+A V GP LL P
Sbjct: 789 LPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRP 832
>ref|NP_056557.1| myosin IXb [Mus musculus]
gb|AAF00118.1|AF143683_1 (AF143683) unconventional myosin 9bc [Mus musculus]
Length = 1961
Score = 225 bits (569), Expect = 3e-58
Identities = 59/171 (34%), Positives = 98/171 (56%), Gaps = 2/171 (1%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 62
FG ++ LT + +E + + G+ EGL+R + +A++ ++L+ AL
Sbjct: 1656 FGVCVD-SLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAA 1714
Query: 63 VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPK 122
V+ HAI G LK +LRELPEPLMTF Y ++++A + E+ ++L A++ + LP+
Sbjct: 1715 VKLEDFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLSAIYAVLDHLPE 1774
Query: 123 ANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLW-PQAEGNITEM 172
ANH ++ LI L K++ +DVN+M+P +AI+ P LL P +T M
Sbjct: 1775 ANHTSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSM 1825
>gb|AAF59636.1| (AC024755) contains similarity to TR:O75160 [Caenorhabditis
elegans]
Length = 604
Score = 224 bits (568), Expect = 4e-58
Identities = 66/162 (40%), Positives = 100/162 (60%), Gaps = 3/162 (1%)
Query: 1 PSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCV 60
P FG PL+EHL+I I+ + C L + GM E G+FRV+ +ASK+K+++AALD
Sbjct: 237 PVFGVPLDEHLSIQKERISGVLTKCCDFLRQNGMNERGIFRVSGNASKIKRIRAALDAGQ 296
Query: 61 VDVQE--YSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACE 118
D E Y+ DPHA+A LK+YLRELP+PL L +W++A N+ E +++ A+ +
Sbjct: 297 FDADEKHYNNDPHAVASTLKAYLRELPDPLTMDSLQSDWVEAINL-EGEERFSAIDRCLK 355
Query: 119 KLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNL 160
K+ + + N+ YL+KFL L ++ M SN+AIV P +
Sbjct: 356 KMTRGHRQNLIYLMKFLCDLEAKREETSMNASNLAIVFAPTM 397
>ref|NP_064656.1| Cdc42 GTPase-activating protein [Mus musculus]
gb|AAD38043.1|AF151363_1 (AF151363) Cdc42 GTPase-activating protein [Mus musculus]
Length = 820
Score = 224 bits (568), Expect = 4e-58
Identities = 46/167 (27%), Positives = 93/167 (55%), Gaps = 4/167 (2%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAAL---DC 58
+FG L E+L SG+++ + +++C + G+ +G++R++ S +++L+ C
Sbjct: 18 AFGCDLTEYLESSGQDVPYVLKSCAEFIETHGI-VDGIYRLSGITSNIQRLRQEFGSDQC 76
Query: 59 CVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACE 118
+ + Y D H + K Y RELP PL+T+ELY+++ +A + + ++ +L + N
Sbjct: 77 PDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHRPEEGQLARIQNVIL 136
Query: 119 KLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQA 165
+LP ++ + YLI+ L+ ++ + M N+A+V PNLL +
Sbjct: 137 ELPPPHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKK 183
>prf||1107276A gene bcr [Homo sapiens]
Length = 589
Score = 224 bits (567), Expect = 5e-58
Identities = 57/164 (34%), Positives = 86/164 (51%), Gaps = 2/164 (1%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVV 61
FG + ++ + + CV + GM+E G++RV+ A+ ++ LKAA D
Sbjct: 369 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 428
Query: 62 DVQEYSA--DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEK 119
DV + D +AIAG LK Y RELPEPL T E Y + + + + K + N
Sbjct: 429 DVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLS 488
Query: 120 LPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP 163
LP+AN +L+ L +++E + VNKM+ N+A V GP LL P
Sbjct: 489 LPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRP 532
>ref|NP_037116.1| unconventional myosin from rat 3 [Rattus norvegicus]
pir||S54307 myosin heavy chain - rat
emb|CAA54700.1| (X77609) myosin heavy chain [Rattus norvegicus]
Length = 1980
Score = 224 bits (567), Expect = 5e-58
Identities = 59/171 (34%), Positives = 98/171 (56%), Gaps = 2/171 (1%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 62
FG ++ LT + +E + + G+ EGL+R + +A++ ++L+ AL
Sbjct: 1658 FGVCVD-SLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAT 1716
Query: 63 VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPK 122
V+ HAI G LK +LRELPEPLMTF Y ++++A + E+ ++L A++ + LP+
Sbjct: 1717 VKLEDFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLDHLPE 1776
Query: 123 ANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLW-PQAEGNITEM 172
ANH ++ LI L K++ +DVN+M+P +AI+ P LL P +T M
Sbjct: 1777 ANHTSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSM 1827
>pir||T39954 probable gtpase activating protein homolog - fission yeast
(Schizosaccharomyces pombe)
emb|CAA22624.1| (AL035065) putative gtpase activating protein homolog
[Schizosaccharomyces pombe]
Length = 695
Score = 222 bits (563), Expect = 1e-57
Identities = 53/182 (29%), Positives = 97/182 (53%), Gaps = 4/182 (2%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDC---- 58
FG L+ + I + C + + G+ +G++RV S++++ L++ +
Sbjct: 504 FGARLDAIILREHSNIPNIVMQCTSQVENFGLNLQGIYRVPSSSARVNMLRSQFENNPLL 563
Query: 59 CVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACE 118
+ ++Y D HA+A LK + REL EPL+ ++I A NV+++ ++ A+ A
Sbjct: 564 QLHTPEDYENDVHAVADLLKIFFRELREPLIPDNHQRDFIDAGNVEDESRRRDAVHRAIN 623
Query: 119 KLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSL 178
LP AN++ IR+L L+K+ E DVNKM+ +N+AI+ GP ++ I+ T+ +
Sbjct: 624 DLPDANYSTIRHLTIHLAKIKENSDVNKMSTNNLAIIWGPTIIKQATIPEISSFSRTIEI 683
Query: 179 QI 180
I
Sbjct: 684 LI 685
>pir||T27959 hypothetical protein ZK669.1b - Caenorhabditis elegans
emb|CAA85469.1| (Z37093) alternative splicing in ZK669.1a, contains similarity to
Pfam domain: PF00620 (RhoGAP domain), Score=149.9,
E-value=1.5e-41, N=1~cDNA EST yk36g1.5 comes from this
gene [Caenorhabditis elegans]
emb|CAA86848.1| (Z46812) alternative splicing in ZK669.1a, contains similarity to
Pfam domain: PF00620 (RhoGAP domain), Score=149.9,
E-value=1.5e-41, N=1~cDNA EST yk36g1.5 comes from this
gene [Caenorhabditis elegans]
Length = 634
Score = 222 bits (561), Expect = 3e-57
Identities = 56/187 (29%), Positives = 105/187 (55%), Gaps = 13/187 (6%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVV 61
FG PL+ L R I IE + L G++ +G++R SK++++ A +
Sbjct: 176 IFGVPLKGLLEHQNRHIPLIIEKSIDQLQRRGLRAKGIYRTCGVKSKIEEICNAFERSSS 235
Query: 62 D--VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQ---------ASNVQEQDKKL 110
D V + +P +A +K YLR+LPEPL+TFELYD++++ AS +++++
Sbjct: 236 DDEVCLDNENPMNLASVVKLYLRKLPEPLLTFELYDDFVRLGTECCSAQASGSNCEEERV 295
Query: 111 QALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLW--PQAEGN 168
+ L KLP N+ +++++ L+++S + +VN M+ SN++ V+ P+L+W P+ +
Sbjct: 296 EQLRQLARKLPVHNYETLKFIMLHLNRVSWFHEVNLMSTSNLSTVIAPSLIWMSPKRIDH 355
Query: 169 ITEMMTT 175
+ +M T
Sbjct: 356 TSAIMHT 362
>gb|AAF46047.1| (AE003434) CG3208 gene product [Drosophila melanogaster]
Length = 494
Score = 222 bits (561), Expect = 3e-57
Identities = 62/184 (33%), Positives = 102/184 (54%), Gaps = 5/184 (2%)
Query: 2 SFGKPLEEHLTIS-GREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDC-- 58
FG L + + +I F + CV + GM +EG++RV+ A +++ LK ALD
Sbjct: 301 VFGTDLTTMVQLEPHHQIPFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDREG 360
Query: 59 CVVDVQEY-SADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNAC 117
D+ E + + IAG LK YLR LP PL+TF+ Y ++ A +Q ++ Q + A
Sbjct: 361 EKTDMSETAYGNVNVIAGTLKLYLRLLPVPLITFQAYPSFMAAGRTGKQAEQRQLMAEAV 420
Query: 118 EKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLL-WPQAEGNITEMMTTV 176
+LP A+H+ ++Y+++ L +++ + VNKM N+A V P L+ PQ N+TE + +
Sbjct: 421 RRLPPAHHSCLQYMLEHLKRVASHYAVNKMNEHNLATVFAPTLIATPQHMTNLTEEIFML 480
Query: 177 SLQI 180
S I
Sbjct: 481 SSLI 484
>gb|AAF49953.1| (AE003542) CG6811 gene product [Drosophila melanogaster]
Length = 476
Score = 220 bits (556), Expect = 1e-56
Identities = 62/178 (34%), Positives = 101/178 (55%), Gaps = 4/178 (2%)
Query: 3 FGKPLEEHLTISGR--EIAFPIEACVTMLLECG-MQEEGLFRVAPSASKLKKLKAALDCC 59
FG PL+ + S I + CV L G + EG+FR + + S++ LK ++
Sbjct: 274 FGVPLKFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRG 333
Query: 60 VVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEK 119
DV S + H IAG LKS+LR+L EPL+TFELY++ + ++++ EK
Sbjct: 334 -EDVDLKSVNVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIREK 392
Query: 120 LPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVS 177
LP+ N+ +Y+++FL ++ + +D+NKMT SN+AIV GPN LW ++ E + ++
Sbjct: 393 LPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSRSTSTSLEEIAPIN 450
>pir||T27958 hypothetical protein ZK669.1a - Caenorhabditis elegans
emb|CAA85468.1| (Z37093) alternative splicing in ZK669.1b, contains similarity to
Pfam domain: PF00620 (RhoGAP domain), Score=149.9,
E-value=1.5e-41, N=1~cDNA EST yk39b7.5 comes from this
gene~cDNA EST yk50c2.5 comes from this gene~cDNA EST
yk39b7.3 comes from this ge>
emb|CAA86847.1| (Z46812) alternative splicing in ZK669.1b, contains similarity to
Pfam domain: PF00620 (RhoGAP domain), Score=149.9,
E-value=1.5e-41, N=1~cDNA EST yk39b7.5 comes from this
gene~cDNA EST yk50c2.5 comes from this gene~cDNA EST
yk39b7.3 comes from this ge>
Length = 863
Score = 219 bits (555), Expect = 1e-56
Identities = 56/187 (29%), Positives = 105/187 (55%), Gaps = 13/187 (6%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVV 61
FG PL+ L R I IE + L G++ +G++R SK++++ A +
Sbjct: 405 IFGVPLKGLLEHQNRHIPLIIEKSIDQLQRRGLRAKGIYRTCGVKSKIEEICNAFERSSS 464
Query: 62 D--VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQ---------ASNVQEQDKKL 110
D V + +P +A +K YLR+LPEPL+TFELYD++++ AS +++++
Sbjct: 465 DDEVCLDNENPMNLASVVKLYLRKLPEPLLTFELYDDFVRLGTECCSAQASGSNCEEERV 524
Query: 111 QALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLW--PQAEGN 168
+ L KLP N+ +++++ L+++S + +VN M+ SN++ V+ P+L+W P+ +
Sbjct: 525 EQLRQLARKLPVHNYETLKFIMLHLNRVSWFHEVNLMSTSNLSTVIAPSLIWMSPKRIDH 584
Query: 169 ITEMMTT 175
+ +M T
Sbjct: 585 TSAIMHT 591
>pir||A38218 GAP-associated protein p190 - rat
Length = 1493
Score = 215 bits (543), Expect = 3e-55
Identities = 50/162 (30%), Positives = 89/162 (54%), Gaps = 2/162 (1%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCC-VV 61
FG PL +T I IE C+ + G+ EG++RV+ + S+++ L+ D +
Sbjct: 1227 FGVPLTTVVTPEK-PIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNL 1285
Query: 62 DVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLP 121
D+ E + +AGA+KS+ EL + L+ + + + ++A + ++++KL AL +K P
Sbjct: 1286 DLAEKDFTVNTVAGAMKSFFSELRDRLVRYSMQIDLVEAHKINDREQKLHALKEVLKKFP 1345
Query: 122 KANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP 163
K NH +Y+I L+++S VN MT N++I P L+ P
Sbjct: 1346 KENHEVFKYVISHLNRVSHNNKVNLMTSENLSICFWPTLMRP 1387
>sp|Q12979|ABR_HUMAN ACTIVE BREAKPOINT CLUSTER REGION-RELATED PROTEIN
pir||A49307 98K GTPase-activating protein ABR, brain - human
gb|AAC50063.1| (U01147) guanine nucleotide regulatory protein [Homo sapiens]
Length = 859
Score = 213 bits (539), Expect = 1e-54
Identities = 50/164 (30%), Positives = 87/164 (52%), Gaps = 2/164 (1%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVV 61
FG + ++ + + CV + + G++E G++R++ A+ ++ LKA D
Sbjct: 644 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 703
Query: 62 DVQEYSA--DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEK 119
D+ + D +AIAG LK Y RELPEPL+T LY +++ + + K + +
Sbjct: 704 DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRS 763
Query: 120 LPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP 163
LP N +L++ L +++E + +NKM+ N+A V GP LL P
Sbjct: 764 LPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRP 807
>gb|AAF22154.1|AF133093_9 (AF133093) protein with characteristics of a rhoGAP [Mus musculus]
Length = 955
Score = 209 bits (529), Expect = 1e-53
Identities = 53/187 (28%), Positives = 102/187 (54%), Gaps = 11/187 (5%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 62
FG LE+ + SG+ + +E+C+ + G+Q EG+FRV+ + +++ +++ A + D
Sbjct: 516 FGGDLEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQARISEIRDAFERG-ED 574
Query: 63 VQEYSADPH---AIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEK 119
E H ++AG LK Y R L PL ++++E + ++ ++ ++++ + + K
Sbjct: 575 PLEKGCTVHDLDSVAGVLKLYFRSLEPPLFPLDMFNELLASAELEVVGERVEPVSHLLFK 634
Query: 120 LPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQA-------EGNITEM 172
LP+ +RYL FL+ L++Y D N M N+A+ GP LL A +G + ++
Sbjct: 635 LPRPVLVVLRYLFTFLNHLAQYSDENMMDSYNLAVCFGPTLLPVPAGQDPVALQGRVNQL 694
Query: 173 MTTVSLQ 179
+ T+ LQ
Sbjct: 695 VQTLILQ 701
>ref|XP_010255.1| similar to oligophrenin 1 (H. sapiens) [Homo sapiens]
Length = 643
Score = 209 bits (529), Expect = 2e-53
Identities = 57/178 (32%), Positives = 93/178 (52%), Gaps = 6/178 (3%)
Query: 1 PSFGKPLEEHLTISGREIAF-PIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAAL--D 57
P + P+ + + E+ F + C+ ++ G++ EGL+R S +++KL A
Sbjct: 209 PIYHSPITKQQEMELNEVGFKFVRKCINIIETKGIKTEGLYRTVGSNIQVQKLLNAFFDP 268
Query: 58 CCVVDVQEYSA--DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWN 115
C DV +++ D I +LK YLR L EP+MT+ L+ E + A+ D +L A+ +
Sbjct: 269 KCPGDVDFHNSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHS 328
Query: 116 ACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMM 173
KLP+ N + LI+ L + E+ N MTPSNM ++ GP L+ Q E + MM
Sbjct: 329 LVYKLPEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQ-EDTVAAMM 385
>pir||B47485 ABR protein 2 - human
Length = 813
Score = 208 bits (527), Expect = 3e-53
Identities = 50/164 (30%), Positives = 86/164 (51%), Gaps = 2/164 (1%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVV 61
FG + + + + CV + + G++E G++R++ A+ ++ LKA D
Sbjct: 598 VFGVKISVVTKREVQGAPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 657
Query: 62 DVQEYSA--DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEK 119
D+ + D +AIAG LK Y RELPEPL+T LY +++ + + K + +
Sbjct: 658 DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLVRS 717
Query: 120 LPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP 163
LP N +L++ L +++E + +NKM+ N+A V GP LL P
Sbjct: 718 LPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRP 761
>pir||T18289 racGAP protein - slime mold (Dictyostelium discoideum)
emb|CAA71241.1| (Y10159) racGAP [Dictyostelium discoideum]
Length = 1335
Score = 208 bits (527), Expect = 3e-53
Identities = 58/179 (32%), Positives = 96/179 (53%), Gaps = 8/179 (4%)
Query: 2 SFGKPLEEHLTISGR-----EIAFPIEACVTMLLE-CGMQEEGLFRVAPSASKLKKLKAA 55
FG LE +T + E+ + + L + + EEG+FR+ + ++++K +
Sbjct: 6 IFGIDLETIVTTQNQAAFISEVPKIVAQVIEWLDKFNAVNEEGIFRIPGNGVTIQEIKKS 65
Query: 56 LDCCVVDVQEYS-ADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALW 114
D D+ +++ +D H++AG LK YLRELPEPL + Y +I+ + ++ L
Sbjct: 66 FDEGKGDLSKFNSSDIHSVAGVLKLYLRELPEPLFIWRYYSTFIKVIKNPDHLQRALHLR 125
Query: 115 NACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMM 173
C LPK N + + L+ FL+K+S VNKMT N+A V PN+L PQ E + ++M
Sbjct: 126 MLCYGLPKVNRDLVLSLMVFLNKISLNNRVNKMTSQNLATVFAPNILRPQKE-TLNQIM 183
>ref|NP_002538.1| oligophrenin 1, Rho-GTPase acivating protein [Homo sapiens]
emb|CAA04579.1| (AJ001189) oligophrenin 1 [Homo sapiens]
emb|CAB96181.1| (AJ248245) oligophrenin-1 [Homo sapiens]
Length = 802
Score = 208 bits (526), Expect = 3e-53
Identities = 57/178 (32%), Positives = 93/178 (52%), Gaps = 6/178 (3%)
Query: 1 PSFGKPLEEHLTISGREIAF-PIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAAL--D 57
P + P+ + + E+ F + C+ ++ G++ EGL+R S +++KL A
Sbjct: 368 PIYHSPITKQQEMELNEVGFKFVRKCINIIETKGIKTEGLYRTVGSNIQVQKLLNAFFDP 427
Query: 58 CCVVDVQEYSA--DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWN 115
C DV +++ D I +LK YLR L EP+MT+ L+ E + A+ D +L A+ +
Sbjct: 428 KCPGDVDFHNSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHS 487
Query: 116 ACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMM 173
KLP+ N + LI+ L + E+ N MTPSNM ++ GP L+ Q E + MM
Sbjct: 488 LVYKLPEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQ-EDTVAAMM 544
>ref|NP_001083.1| active BCR-related gene [Homo sapiens]
pir||A47485 ABR protein 1 - human
gb|AAC37519.1| (L19704) alternative first exon [Homo sapiens]
Length = 822
Score = 207 bits (524), Expect = 5e-53
Identities = 50/164 (30%), Positives = 86/164 (51%), Gaps = 2/164 (1%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVV 61
FG + + + + CV + + G++E G++R++ A+ ++ LKA D
Sbjct: 607 VFGVKISVVTKREVQGAPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 666
Query: 62 DVQEYSA--DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEK 119
D+ + D +AIAG LK Y RELPEPL+T LY +++ + + K + +
Sbjct: 667 DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLVRS 726
Query: 120 LPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP 163
LP N +L++ L +++E + +NKM+ N+A V GP LL P
Sbjct: 727 LPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRP 770
>gb|AAF45386.1| (AE002567) EG:23E12.2 gene product [Drosophila melanogaster]
Length = 718
Score = 206 bits (522), Expect = 9e-53
Identities = 61/173 (35%), Positives = 92/173 (52%), Gaps = 12/173 (6%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCC--- 59
FG + + L R+I F I AC+ + GM E G +RV+ SAS L KLK A +
Sbjct: 510 FGAKMSQVLKREKRDIPFIIGACIREVERRGMLEVGCYRVSGSASDLAKLKKAFESGEYM 569
Query: 60 -VVDVQE-----YSADPHAIAGALKSYLRELPEPLMTFELYDEWIQ---ASNVQEQDKKL 110
++D E D H++ G LK++LRELPE L T +LY + A + + ++
Sbjct: 570 ALMDAYEAEQLLREVDIHSVTGILKTFLRELPEALFTDQLYPRFFDTFSAFSNNNESTRI 629
Query: 111 QALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP 163
L E+LP+AN +I ++ L ++ E + NKM+ N+A+V GP LL P
Sbjct: 630 NELLKVFEELPQANKASITSILDHLIRVHEKETDNKMSLHNLAMVFGPTLLRP 682
>dbj|BAA96025.1| (AB040934) KIAA1501 protein [Homo sapiens]
Length = 735
Score = 204 bits (517), Expect = 4e-52
Identities = 50/179 (27%), Positives = 101/179 (55%), Gaps = 5/179 (2%)
Query: 2 SFGKPLEEHL-TISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCV 60
+FG LEE + + + AC ++ G++ G++RV + + + L+ L+
Sbjct: 493 AFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGP 552
Query: 61 VDV---QEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNAC 117
D+ E D + I+ LKS+ R+LPEPL T + Y+++I+A+ +++ ++++ L
Sbjct: 553 GDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLI 612
Query: 118 EKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTV 176
LP + +++L+ L ++++ + NKM P N+A+V GP L+ +E N+T+M+T +
Sbjct: 613 RDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVR-TSEDNMTDMVTHM 670
>sp|P98171|RHG4_HUMAN RHO-GTPASE-ACTIVATING PROTEIN 4 (RHO-GAP HEMATOPOIETIC PROTEIN C1)
(P115) (KIAA0131)
pir||I38100 rho-GTPase-activating protein 4 [accepted] - human
emb|CAA55394.1| (X78817) p115 [Homo sapiens]
Length = 946
Score = 202 bits (510), Expect = 3e-51
Identities = 52/186 (27%), Positives = 101/186 (53%), Gaps = 9/186 (4%)
Query: 3 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 62
FG +E+ + SG+ + +E+C+ + G+Q EG+FRV+ + ++ +++ A +
Sbjct: 505 FGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRVSEIRDAFERGEDP 564
Query: 63 VQE--YSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL 120
+ E + D ++AG LK Y R L PL +L+ E + +S +++ ++++ + +L
Sbjct: 565 LVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEDTAERVEHVSRLLWRL 624
Query: 121 PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQA-------EGNITEMM 173
P +RYL FL+ L++Y D N M P N+A+ GP LL A +G + +++
Sbjct: 625 PAPVLVVLRYLFTFLNHLAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLV 684
Query: 174 TTVSLQ 179
T+ +Q
Sbjct: 685 QTLIVQ 690
>pir||B53764 beta2-chimerin, cerebellar - rat (fragment)
Length = 443
Score = 197 bits (499), Expect = 4e-50
Identities = 47/174 (27%), Positives = 89/174 (51%), Gaps = 3/174 (1%)
Query: 2 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVV 61
+ L + + ++ C+ + G++ EGL+RV+ ++ +K A D
Sbjct: 249 VYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGE 308
Query: 62 DVQEYSA---DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACE 118
+ D + I GALK Y R+LP P++T++ Y ++I+A+ + D++L+A+
Sbjct: 309 KADISANIYPDINIITGALKLYFRDLPIPIITYDTYSKFIEAAKISNADERLEAVHEVLM 368
Query: 119 KLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEM 172
LP A++ +RYL+ L K++ + N M N+ IV GP L+ P + +T +
Sbjct: 369 LLPPAHYETLRYLMIHLKKVTMNEKDNLMNAENLGIVFGPTLMRPPEDSTLTTL 422
CPU time: 45.77 user secs. 1.59 sys. secs 47.36 total secs.
Database: nr
Posted date: Dec 10, 2000 7:21 PM
Number of letters in database: 188,047,558
Number of sequences in database: 594,795
Lambda K H
0.314 0.194 0.588
Gapped
Lambda K H
0.270 0.0681 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 107070958
Number of Sequences: 594795
Number of extensions: 6411145
Number of successful extensions: 11745
Number of sequences better than 10.0: 278
Number of HSP's better than 10.0 without gapping: 255
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 11123
Number of HSP's gapped (non-prelim): 285
length of query: 180
length of database: 188,047,558
effective HSP length: 55
effective length of query: 125
effective length of database: 155,333,833
effective search space: 19416729125
effective search space used: 19416729125
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (20.9 bits)
S2: 70 (31.1 bits)