BLAST TEM9

BLAST against nr ProteinDB

	BLAST against nr ProteinDB

BLASTP 2.1.1 [Aug-8-2000]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 
         (1331 letters)

Database: nr
           808,980 sequences; 257,180,598 total letters

Distribution of 184 Blast Hits on the Query Sequence


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

ref|NP_116166.2|  (NM_032777) tumor endothelial marker 5 pre...  2248  0.0
ref|NP_473385.1|  (NM_054044) RIKEN cDNA 9530074E10 [Mus mus...  1990  0.0
dbj|BAA96055.1|  (AB040964) KIAA1531 protein [Homo sapiens]      1772  0.0
ref|XP_039196.1|  (XM_039196) DKFZP434C211 protein [Homo sap...   794  0.0
pir||T14774  hypothetical protein DKFZp434C211.1 - human (fr...   466  e-129
ref|XP_039194.1|  (XM_039194) hypothetical protein FLJ14390 ...   265  5e-69
gb|AAF48247.1|  (AE003492) CG15744 gene product [Drosophila ...   253  1e-65
ref|XP_032373.2|  (XM_032373) hypothetical protein XP_032373...   228  5e-58
dbj|BAB47457.1|  (AB058731) KIAA1828 protein [Homo sapiens]       181  7e-44
ref|XP_039195.1|  (XM_039195) hypothetical protein XP_039195...   157  8e-37
ref|XP_033711.1|  (XM_033711) DKFZP586O1624 protein [Homo sa...   105  4e-21
gb|AAK62357.1|AF381545_1  (AF381545) membrane glycoprotein L...   105  4e-21
dbj|BAB40659.1|  (AB050468) membrane glycoprotein LIG-1 [Hom...   105  4e-21
ref|NP_032403.1|  (NM_008377) integral membrane glycoprotein...   104  9e-21
ref|NP_055628.1|  (NM_014813) KIAA0806 gene product [Homo sa...   102  4e-20
ref|NP_476729.1|  (NM_057381) sli-P2 [Drosophila melanogaster]    100  1e-19
ref|NP_476728.1|  (NM_057380) sli-P1 [Drosophila melanogaste...   100  1e-19
prf||1704200A  slit gene [Drosophila sp.]                         100  1e-19
pir||B36665  slit protein 2 precursor - fruit fly (Drosophil...   100  1e-19
sp|P24014|SLIT_DROME  SLIT PROTEIN PRECURSOR >gi|103391|pir|...   100  1e-19
gb|AAF58053.1|  (AE003808) CG8434 gene product [Drosophila m...   100  2e-19
gb|AAD44758.1|AF144627_1  (AF144627) SLIT1 [Mus musculus]          96  3e-18
ref|XP_039760.1|  (XM_039760) Melanoma associated gene [Homo...    95  6e-18
dbj|BAA13219.1|  (D86983) similar to D.melanogaster peroxida...    95  6e-18
ref|XP_047964.2|  (XM_047964) slit (Drosophila) homolog 3 [H...    94  1e-17
ref|NP_003053.1|  (NM_003062) slit (Drosophila) homolog 3; s...    94  1e-17
ref|NP_476727.1|  (NM_057379) sli-P3 [Drosophila melanogaste...    94  1e-17
gb|AAD26567.1|AF126540_1  (AF126540) slit protein [Drosophil...    94  1e-17
ref|NP_075242.1|  (NM_022953) Slit1 [Rattus norvegicus] >gi|...    94  2e-17
gb|AAL14445.1|AF387318_1  (AF387318) slit-3 [Gallus gallus]        93  2e-17
dbj|BAB31253.1|  (AK018522) putative [Mus musculus]                93  2e-17
gb|AAG36773.1|  (AF210321) Slit2 [Danio rerio]                     92  4e-17
gb|AAD25540.1|AF133730_1  (AF133730) Slit1 [Rattus norvegicus]     92  7e-17
ref|XP_050940.1|  (XM_050940) slit (Drosophila) homolog 1 [H...    91  9e-17
ref|NP_003052.1|  (NM_003061) slit (Drosophila) homolog 1; s...    91  9e-17
ref|XP_003557.4|  (XM_003557) hypothetical protein XP_003557...    91  1e-16
gb|AAG36772.1|AF210320_1  (AF210320) Slit3 [Danio rerio]           89  3e-16
gb|AAL14447.1|  (AF387320) slit-2 [Gallus gallus]                  89  5e-16
ref|NP_072154.1|  (NM_022632) slit (Drosophila) homolog 2 [R...    89  5e-16
gb|AAD25539.1|AF133270_1  (AF133270) SLIT2 [Homo sapiens]          89  6e-16
ref|NP_034016.1|  (NM_009886) cadherin EGF LAG seven-pass G-...    89  6e-16
ref|NP_112611.1|  (NM_031321) slit (Drosophila) homolog 3 [R...    89  6e-16
gb|AAD44760.1|AF144629_1  (AF144629) SLIT3 [Mus musculus]          88  8e-16
ref|NP_055061.1|  (NM_014246) cadherin EGF LAG seven-pass G-...    88  1e-15
emb|CAB38413.1|  (AL031588) dJ1163J1.1 (mostly supported by ...    88  1e-15
dbj|BAB23775.1|  (AK005049) putative [Mus musculus]                87  2e-15
gb|AAD44759.1|AF144628_1  (AF144628) SLIT2 [Mus musculus]          87  2e-15
gb|AAD04309.1|  (AF055585) neurogenic extracellular slit pro...    87  2e-15
ref|NP_004778.1|  (NM_004787) slit (Drosophila) homolog 2 [H...    87  2e-15
gb|AAL02123.1|  (AY046070) Slit [Xenopus laevis]                   86  3e-15

>ref|NP_116166.2| (NM_032777) tumor endothelial marker 5 precursor [Homo sapiens]
 gb|AAL11992.1|AF378755_1 (AF378755) tumor endothelial marker 5 precursor [Homo sapiens]
          Length = 1331

 Score = 2248 bits (5762), Expect = 0.0
 Identities = 1118/1302 (85%), Positives = 1118/1302 (85%)

Query: 30   CPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSXXXXXXXXXXXXXXNGTVTLLLSNNKI 89
            CPLSIRSCKCSGERPKGLSGGVPGPARRRVVCS              NGTVTLLLSNNKI
Sbjct: 30   CPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSGGDLPEPPEPGLLPNGTVTLLLSNNKI 89

Query: 90   TGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLP 149
            TGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLP
Sbjct: 90   TGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLP 149

Query: 150  RLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHT 209
            RLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHT
Sbjct: 150  RLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHT 209

Query: 210  LCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRLPFQCSASYLGND 269
            LCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRLPFQCSASYLGND
Sbjct: 210  LCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRLPFQCSASYLGND 269

Query: 270  TRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWASGEWECTVSMAQGN 329
            TRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWASGEWECTVSMAQGN
Sbjct: 270  TRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWASGEWECTVSMAQGN 329

Query: 330  ASKKVEIVVLETSASYCPAERVANNRGDFRWPRTLAGITAYQSCLQYPFTSVPLGGGAPG 389
            ASKKVEIVVLETSASYCPAERVANNRGDFRWPRTLAGITAYQSCLQYPFTSVPLGGGAPG
Sbjct: 330  ASKKVEIVVLETSASYCPAERVANNRGDFRWPRTLAGITAYQSCLQYPFTSVPLGGGAPG 389

Query: 390  TRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAAS 449
            TRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAAS
Sbjct: 390  TRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAAS 449

Query: 450  FSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKACSRIV 509
            FSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKACSRIV
Sbjct: 450  FSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKACSRIV 509

Query: 510  GALERIGGAALSPHAQHISVNARNVALEAYLIKPHSYVGLTCTAFQRREGGVPGTRPGSP 569
            GALERIGGAALSPHAQHISVNARNVALEAYLIKPHSYVGLTCTAFQRREGGVPGTRPGSP
Sbjct: 510  GALERIGGAALSPHAQHISVNARNVALEAYLIKPHSYVGLTCTAFQRREGGVPGTRPGSP 569

Query: 570  GQNXXXXXXXXADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQXXXXXXXXXXXXXXXX 629
            GQN        ADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQ                
Sbjct: 570  GQNPPPEPEPPADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQLPPSLFSSLPAALAPP 629

Query: 630  XXXDCTLQLLVFRNGRLFHSHSNTSXXXXXXXXXXXXVATPVIFAGTSGCGVGNLTEPVA 689
               DCTLQLLVFRNGRLFHSHSNTS            VATPVIFAGTSGCGVGNLTEPVA
Sbjct: 630  VPPDCTLQLLVFRNGRLFHSHSNTSRPGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVA 689

Query: 690  VSLRHWAEGAEPVAAWWSQEGPGEAGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMELS 749
            VSLRHWAEGAEPVAAWWSQEGPGEAGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMELS
Sbjct: 690  VSLRHWAEGAEPVAAWWSQEGPGEAGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMELS 749

Query: 750  AFPREVGGAGAGLHPVVYPXXXXXXXXXXXXXXTYILNHSSIRVSRKGWHMLLNLCFHIA 809
            AFPREVGGAGAGLHPVVYP              TYILNHSSIRVSRKGWHMLLNLCFHIA
Sbjct: 750  AFPREVGGAGAGLHPVVYPCTALLLLCLFATIITYILNHSSIRVSRKGWHMLLNLCFHIA 809

Query: 810  MTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDP 869
            MTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDP
Sbjct: 810  MTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDP 869

Query: 870  ALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALIL 929
            ALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALIL
Sbjct: 870  ALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALIL 929

Query: 930  LITWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGSTRLRXXXXXXXXXXXXXATG 989
            LITWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGSTRLR             ATG
Sbjct: 930  LITWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGSTRLRGSGPLLSDSGSLLATG 989

Query: 990  SARVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGV 1049
            SARVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGV
Sbjct: 990  SARVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGV 1049

Query: 1050 AASALGLFVFTHHCARRRDVRXXXXXXXXXXXXXXXXXXXXXXXXXXEDGSPVFXXXXXX 1109
            AASALGLFVFTHHCARRRDVR                          EDGSPVF      
Sbjct: 1050 AASALGLFVFTHHCARRRDVRASWRACCPPASPAAPHAPPRALPAAAEDGSPVFGEGPPS 1109

Query: 1110 XXXXXXXXXXXXXXXXXCKLTNLQLAQSQVCXXXXXXXXXXXXXXXXTRGNLAHRHPNNV 1169
                             CKLTNLQLAQSQVC                TRGNLAHRHPNNV
Sbjct: 1110 LKSSPSGSSGHPLALGPCKLTNLQLAQSQVCEAGAAAGGEGEPEPAGTRGNLAHRHPNNV 1169

Query: 1170 HHGRRAHKSRAKGHRAGEACGKNXXXXXXXXXXXXXXXXXXXXXXXHNSPTDSYLGSSRN 1229
            HHGRRAHKSRAKGHRAGEACGKN                       HNSPTDSYLGSSRN
Sbjct: 1170 HHGRRAHKSRAKGHRAGEACGKNRLKALRGGAAGALELLSSESGSLHNSPTDSYLGSSRN 1229

Query: 1230 SPGAGLQLEGEPMLTPSEGSDTSAAPLXXXXXXXXXXXXXXXXLKGGGALEKESHRRSYP 1289
            SPGAGLQLEGEPMLTPSEGSDTSAAPL                LKGGGALEKESHRRSYP
Sbjct: 1230 SPGAGLQLEGEPMLTPSEGSDTSAAPLSEAGRAGQRRSASRDSLKGGGALEKESHRRSYP 1289

Query: 1290 LNAASLNGAPKGGKYDDVTLMGAEVASGGCMKTGLWKSETTV 1331
            LNAASLNGAPKGGKYDDVTLMGAEVASGGCMKTGLWKSETTV
Sbjct: 1290 LNAASLNGAPKGGKYDDVTLMGAEVASGGCMKTGLWKSETTV 1331



>ref|NP_473385.1| (NM_054044) RIKEN cDNA 9530074E10 [Mus musculus]
 gb|AAL11996.1|AF378759_1 (AF378759) tumor endothelial marker 5 precursor [Mus musculus]
          Length = 1329

 Score = 1990 bits (5099), Expect = 0.0
 Identities = 999/1305 (76%), Positives = 1048/1305 (79%), Gaps = 8/1305 (0%)

Query: 30   CPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSXXXXXXXXXXXXXXNGTVTLLLSNNKI 89
            CP+ IR CKCSGERPKGLSGG   PARRRVVC               NGT+TLLLSNNKI
Sbjct: 30   CPVPIRGCKCSGERPKGLSGGAHNPARRRVVCGGGDLPEPPDPGLLPNGTITLLLSNNKI 89

Query: 90   TGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLP 149
            TGLRNGSFLGLSLLEKLDLR+N+ISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLP
Sbjct: 90   TGLRNGSFLGLSLLEKLDLRSNVISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLP 149

Query: 150  RLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHT 209
            RLLRLNISGNI+SSLQPGVFDELPALK+VD GTEFLTCDC LRWLLPWA+N SLQLSE T
Sbjct: 150  RLLRLNISGNIYSSLQPGVFDELPALKIVDFGTEFLTCDCRLRWLLPWARNHSLQLSERT 209

Query: 210  LCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRLPFQCSASYLGND 269
            LCAYPSALHA AL SLQE+QL CEGALELHTH+LIPSLRQVVFQGDRLPFQCSASYLGND
Sbjct: 210  LCAYPSALHAHALSSLQESQLRCEGALELHTHYLIPSLRQVVFQGDRLPFQCSASYLGND 269

Query: 270  TRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWASGEWECTVSMAQGN 329
            TRI WYHN AP+E DEQAGI+LAE+LIHDCTFITSELTLSHIGVWASGEWEC+VS  QGN
Sbjct: 270  TRIHWYHNGAPMESDEQAGIVLAENLIHDCTFITSELTLSHIGVWASGEWECSVSTVQGN 329

Query: 330  ASKKVEIVVLETSASYCPAERVANNRGDFRWPRTLAGITAYQSCLQYPFTSVPLGGGAPG 389
             SKKVEIVVLETSASYCPAERV NNRGDFRWPRTLAGITAYQSCLQYPFTSVPL GGAPG
Sbjct: 330  TSKKVEIVVLETSASYCPAERVTNNRGDFRWPRTLAGITAYQSCLQYPFTSVPLSGGAPG 389

Query: 390  TRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAAS 449
            TRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAAS
Sbjct: 390  TRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAAS 449

Query: 450  FSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKACSRIV 509
            FSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKACS IV
Sbjct: 450  FSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKACSGIV 509

Query: 510  GALERIGGAALSPHAQHISVNARNVALEAYLIKPHSYVGLTCTAFQRREGGVPGTRPGSP 569
            GALERIGGAALSPHAQHISVN+RNVALEAYLIKPHSYVGLTCTAFQRRE GV G +P S 
Sbjct: 510  GALERIGGAALSPHAQHISVNSRNVALEAYLIKPHSYVGLTCTAFQRREVGVSGAQPSSV 569

Query: 570  GQNXXXXXXXXADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQXXXXXXXXXXXXXXXX 629
            GQ+        ADQQLRFRCTTGRPN+SLSSFHIKNSVALASIQ                
Sbjct: 570  GQDAPVEPEPLADQQLRFRCTTGRPNISLSSFHIKNSVALASIQLPPSLFSTLPAALAPP 629

Query: 630  XXXDCTLQLLVFRNGRLFHSH-SNTSXXXXXXXXXXXXVATPVIFAGTSGCGVGNLTEPV 688
               DCTLQLLVFRNGRLF SH +NTS            VATPVIFAGTSGCGVGNLTEPV
Sbjct: 630  VPPDCTLQLLVFRNGRLFRSHGNNTSRPGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPV 689

Query: 689  AVSLRHWAEGAEPVAAWWSQEGPGEAGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMEL 748
            AVSLRHWAEGA+P+AAWW+Q+GP   GGW+SEGC+LR SQPNVS+L+CQHLGNVAVLMEL
Sbjct: 690  AVSLRHWAEGADPMAAWWNQDGP---GGWSSEGCRLRYSQPNVSSLYCQHLGNVAVLMEL 746

Query: 749  SAFPREVGGAGAGLHPVVYPXXXXXXXXXXXXXXTYILNHSSIRVSRKGWHMLLNLCFHI 808
            +AFPRE GG+GAGLHPVVYP              TYILNHSSI VSRKGWHMLLNLCFH+
Sbjct: 747  NAFPREAGGSGAGLHPVVYPCTALLLLCLFSTIITYILNHSSIHVSRKGWHMLLNLCFHM 806

Query: 809  AMTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGD 868
            AMTSAVF GG+TLTNYQMVCQAVGITLHYSSLS+LLWMGVKARVLHKEL+WRAPP +EG+
Sbjct: 807  AMTSAVFVGGVTLTNYQMVCQAVGITLHYSSLSSLLWMGVKARVLHKELSWRAPPLEEGE 866

Query: 869  PALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALI 928
             A P P PMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALI
Sbjct: 867  AAPPGPRPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALI 926

Query: 929  LLITWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGSTRLRXXXXXXXXXXXXXAT 988
            L ITWIYFLCAGL LR  +AQNPK GN R SLE GEELRGSTRLR             AT
Sbjct: 927  LPITWIYFLCAGLHLRSHVAQNPKQGN-RISLEPGEELRGSTRLRSSGVLLNDSGSLLAT 985

Query: 989  GSARVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYG 1048
             SA VGTP PPEDGD +YSPGVQLGAL+TTHFLYLAMWACGALAVSQRWLPRVVCSCLYG
Sbjct: 986  VSAGVGTPAPPEDGDGVYSPGVQLGALMTTHFLYLAMWACGALAVSQRWLPRVVCSCLYG 1045

Query: 1049 VAASALGLFVFTHHCARRRDVRXXXXXXXXXXXXXXXXXXXXXXXXXXEDGSPVFXXXXX 1108
            VAASALGLFVFTHHCARRRDVR                          EDGSPV      
Sbjct: 1046 VAASALGLFVFTHHCARRRDVRASWRACCPPASPSASHVPARALPTATEDGSPVL-GEGP 1104

Query: 1109 XXXXXXXXXXXXXXXXXXCKLTNLQLAQSQVCXXXXXXXXXXXXXXXXTRGNLAHRHPNN 1168
                              CKLTNLQ+AQSQVC                +RG+LA RH NN
Sbjct: 1105 ASLKSSPSGSSGRAPPPPCKLTNLQVAQSQVCEASVAARGDGEPEPTGSRGSLAPRHHNN 1164

Query: 1169 VHHGRRAHKSRAKGHRAGEACGKNXXXXXXXXXX-XXXXXXXXXXXXXHNSPTDSYLGSS 1227
            +HHGRR HKSRAKGHRAGE  GK+                        HNSP+DSY GSS
Sbjct: 1165 LHHGRRVHKSRAKGHRAGETGGKSRLKALRAGTSPGAPELLSSESGSLHNSPSDSYPGSS 1224

Query: 1228 RNSPGAGLQLEGEPMLTPSEGSDTSAAPLXXXXXXXXXXXXXXXXLKG-GGALEKESHRR 1286
            RNSPG GL LEGEPMLTPSEGSDTSAAP+                LKG G ALE+ES RR
Sbjct: 1225 RNSPGDGLPLEGEPMLTPSEGSDTSAAPIAETGRPGQRRSASRDNLKGSGSALERESKRR 1284

Query: 1287 SYPLNAASLNGAPKGGKYDDVTLMGAEVASGGCMKTGLWKSETTV 1331
            SYPLN  SLNGAPKGGKY+D ++ GAE  +GG MKTGLWKSETTV
Sbjct: 1285 SYPLNTTSLNGAPKGGKYEDASVTGAEAIAGGSMKTGLWKSETTV 1329



>dbj|BAA96055.1| (AB040964) KIAA1531 protein [Homo sapiens]
          Length = 1060

 Score = 1772 bits (4538), Expect = 0.0
 Identities = 890/1090 (81%), Positives = 890/1090 (81%), Gaps = 30/1090 (2%)

Query: 242  HLIPSLRQVVFQGDRLPFQCSASYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTF 301
            HLIPSLRQVVFQGDRLPFQCSASYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTF
Sbjct: 1    HLIPSLRQVVFQGDRLPFQCSASYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTF 60

Query: 302  ITSELTLSHIGVWASGEWECTVSMAQGNASKKVEIVVLETSASYCPAERVANNRGDFRWP 361
            ITSELTLSHIGVWASGEWECTVSMAQGNASKKVEIVVLETSASYCPAERVANNRGDFRWP
Sbjct: 61   ITSELTLSHIGVWASGEWECTVSMAQGNASKKVEIVVLETSASYCPAERVANNRGDFRWP 120

Query: 362  RTLAGITAYQSCLQYPFTSVPLGGGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLY 421
            RTLAGITAYQSCLQYPFTSVPLGGGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLY
Sbjct: 121  RTLAGITAYQSCLQYPFTSVPLGGGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLY 180

Query: 422  TFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMV 481
            TFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMV
Sbjct: 181  TFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMV 240

Query: 482  DMASNLMLVDEHLLWLAQREDKACSRIVGALERIGGAALSPHAQHISVNARNVALEAYLI 541
            DMASNLMLVDEHLLWLAQREDKACSRIVGALERIGGAALSPHAQHISVNARNVALEAYLI
Sbjct: 241  DMASNLMLVDEHLLWLAQREDKACSRIVGALERIGGAALSPHAQHISVNARNVALEAYLI 300

Query: 542  KPHSYVGLTCTAFQRREGGVPGTRPGSPGQNXXXXXXXXADQQLRFRCTTGRPNVSLSSF 601
            KPHSYVGLTCTAFQRREGGVPGTRPGSPGQN        ADQQLRFRCTTGRPNVSLSSF
Sbjct: 301  KPHSYVGLTCTAFQRREGGVPGTRPGSPGQNPPPEPEPPADQQLRFRCTTGRPNVSLSSF 360

Query: 602  HIKNSVALASIQXXXXXXXXXXXXXXXXXXXDCTLQLLVFRNGRLFHSHSNTSXXXXXXX 661
            HIKNSVALASIQ                   DCTLQLLVFRNGRLFHSHSNTS       
Sbjct: 361  HIKNSVALASIQLPPSLFSSLPAALAPPVPPDCTLQLLVFRNGRLFHSHSNTSRPGAAGP 420

Query: 662  XXXXXVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGAEPVAAWWSQEGPGEAGGWTSEG 721
                 VATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGAEPVAAWWSQEGPGEAGGWTSEG
Sbjct: 421  GKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGAEPVAAWWSQEGPGEAGGWTSEG 480

Query: 722  CQLRSSQPNVSALHCQHLGNVAVLMELSAFPREVGGAGAGLHPVVYPXXXXXXXXXXXXX 781
            CQLRSSQPNVSALHCQHLGNVAVLMELSAFPREVGGAGAGLHPVVYP             
Sbjct: 481  CQLRSSQPNVSALHCQHLGNVAVLMELSAFPREVGGAGAGLHPVVYPCTALLLLCLFATI 540

Query: 782  XTYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLS 841
             TYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLS
Sbjct: 541  ITYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLS 600

Query: 842  TLLWMGVKARVLHKELTWRAPPPQEGDPALPTPSPMLRFYLIAGGIPLIICGITAAVNIH 901
            TLLWMGVKARVLHKELTWRAPPPQEGDPALPTPSPMLR                      
Sbjct: 601  TLLWMGVKARVLHKELTWRAPPPQEGDPALPTPSPMLR---------------------- 638

Query: 902  NYRDHSPYCWLVWRPSLGAFYIPVALILLITWIYFLCAGLRLRGPLAQNPKAGNSRASLE 961
                    CWLVWRPSLGAFYIPVALILLITWIYFLCAGLRLRGPLAQNPKAGNSRASLE
Sbjct: 639  --------CWLVWRPSLGAFYIPVALILLITWIYFLCAGLRLRGPLAQNPKAGNSRASLE 690

Query: 962  AGEELRGSTRLRXXXXXXXXXXXXXATGSARVGTPGPPEDGDSLYSPGVQLGALVTTHFL 1021
            AGEELRGSTRLR             ATGSARVGTPGPPEDGDSLYSPGVQLGALVTTHFL
Sbjct: 691  AGEELRGSTRLRGSGPLLSDSGSLLATGSARVGTPGPPEDGDSLYSPGVQLGALVTTHFL 750

Query: 1022 YLAMWACGALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRXXXXXXXXXXX 1081
            YLAMWACGALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVR           
Sbjct: 751  YLAMWACGALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASWRACCPPAS 810

Query: 1082 XXXXXXXXXXXXXXXEDGSPVFXXXXXXXXXXXXXXXXXXXXXXXCKLTNLQLAQSQVCX 1141
                           EDGSPVF                       CKLTNLQLAQSQVC 
Sbjct: 811  PAAPHAPPRALPAAAEDGSPVFGEGPPSLKSSPSGSSGHPLALGPCKLTNLQLAQSQVCE 870

Query: 1142 XXXXXXXXXXXXXXXTRGNLAHRHPNNVHHGRRAHKSRAKGHRAGEACGKNXXXXXXXXX 1201
                           TRGNLAHRHPNNVHHGRRAHKSRAKGHRAGEACGKN         
Sbjct: 871  AGAAAGGEGEPEPAGTRGNLAHRHPNNVHHGRRAHKSRAKGHRAGEACGKNRLKALRGGA 930

Query: 1202 XXXXXXXXXXXXXXHNSPTDSYLGSSRNSPGAGLQLEGEPMLTPSEGSDTSAAPLXXXXX 1261
                          HNSPTDSYLGSSRNSPGAGLQLEGEPMLTPSEGSDTSAAPL     
Sbjct: 931  AGALELLSSESGSLHNSPTDSYLGSSRNSPGAGLQLEGEPMLTPSEGSDTSAAPLSEAGR 990

Query: 1262 XXXXXXXXXXXLKGGGALEKESHRRSYPLNAASLNGAPKGGKYDDVTLMGAEVASGGCMK 1321
                       LKGGGALEKESHRRSYPLNAASLNGAPKGGKYDDVTLMGAEVASGGCMK
Sbjct: 991  AGQRRSASRDSLKGGGALEKESHRRSYPLNAASLNGAPKGGKYDDVTLMGAEVASGGCMK 1050

Query: 1322 TGLWKSETTV 1331
            TGLWKSETTV
Sbjct: 1051 TGLWKSETTV 1060



>ref|XP_039196.1| (XM_039196) DKFZP434C211 protein [Homo sapiens]
          Length = 478

 Score =  794 bits (2029), Expect = 0.0
 Identities = 395/440 (89%), Positives = 397/440 (89%)

Query: 325 MAQGNASKKVEIVVLETSASYCPAERVANNRGDFRWPRTLAGITAYQSCLQYPFTSVPLG 384
           MAQGNASKKVEIVVLETSASYCPAERVANNRGDFRWPRTLAGITAYQSCLQYPFTSVPLG
Sbjct: 1   MAQGNASKKVEIVVLETSASYCPAERVANNRGDFRWPRTLAGITAYQSCLQYPFTSVPLG 60

Query: 385 GGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYT 444
           GGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYT
Sbjct: 61  GGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYT 120

Query: 445 AEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKA 504
           AEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDM SNLMLVDEHLLWLAQREDKA
Sbjct: 121 AEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMPSNLMLVDEHLLWLAQREDKA 180

Query: 505 CSRIVGALERIGGAALSPHAQHISVNARNVALEAYLIKPHSYVGLTCTAFQRREGGVPGT 564
           CSRIVGA+ERIGGAALSPHAQHISVNARNVALEAYLIKPHSYVGLTCTAFQRREGGVPGT
Sbjct: 181 CSRIVGAIERIGGAALSPHAQHISVNARNVALEAYLIKPHSYVGLTCTAFQRREGGVPGT 240

Query: 565 RPGSPGQNXXXXXXXXADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQXXXXXXXXXXX 624
           RPGSPGQN        ADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQ           
Sbjct: 241 RPGSPGQNPPPEPEPPADQQLRFRCTTGRPNVSLSSFHIKNSVALASIQLPPSLFSSLPA 300

Query: 625 XXXXXXXXDCTLQLLVFRNGRLFHSHSNTSXXXXXXXXXXXXVATPVIFAGTSGCGVGNL 684
                   DCTLQLLVFRNGRLFHSHSNTS            VATPVIFAGTSGCGVGNL
Sbjct: 301 ALAPPVPPDCTLQLLVFRNGRLFHSHSNTSRPGAAGPGKRRGVATPVIFAGTSGCGVGNL 360

Query: 685 TEPVAVSLRHWAEGAEPVAAWWSQEGPGEAGGWTSEGCQLRSSQPNVSALHCQHLGNVAV 744
           TEPVAVSLRHWAEGAEPVAAWWSQEGPGEAGGWTSEGCQLRSSQPNVSALHCQHLGNVAV
Sbjct: 361 TEPVAVSLRHWAEGAEPVAAWWSQEGPGEAGGWTSEGCQLRSSQPNVSALHCQHLGNVAV 420

Query: 745 LMELSAFPREVGGAGAGLHP 764
           LMELSAFPRE+GGAGA   P
Sbjct: 421 LMELSAFPRELGGAGARSAP 440



>pir||T14774 hypothetical protein DKFZp434C211.1 - human (fragment)
 emb|CAB53694.1| (AL110244) hypothetical protein [Homo sapiens]
          Length = 340

 Score =  466 bits (1186), Expect = e-129
 Identities = 236/340 (69%), Positives = 236/340 (69%)

Query: 992  RVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAA 1051
            RVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAA
Sbjct: 1    RVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAA 60

Query: 1052 SALGLFVFTHHCARRRDVRXXXXXXXXXXXXXXXXXXXXXXXXXXEDGSPVFXXXXXXXX 1111
            SALGLFVFTHHCARRRDVR                          EDGSPVF        
Sbjct: 61   SALGLFVFTHHCARRRDVRASWRACCPPASPAAPHAPPRALPAAAEDGSPVFGEGPPSLK 120

Query: 1112 XXXXXXXXXXXXXXXCKLTNLQLAQSQVCXXXXXXXXXXXXXXXXTRGNLAHRHPNNVHH 1171
                           CKLTNLQLAQSQVC                TRGNLAHRHPNNVHH
Sbjct: 121  SSPSGSSGHPLALGPCKLTNLQLAQSQVCEAGAAAGGEGEPEPAGTRGNLAHRHPNNVHH 180

Query: 1172 GRRAHKSRAKGHRAGEACGKNXXXXXXXXXXXXXXXXXXXXXXXHNSPTDSYLGSSRNSP 1231
            GRRAHKSRAKGHRAGEACGKN                       HNSPTDSYLGSSRNSP
Sbjct: 181  GRRAHKSRAKGHRAGEACGKNRLKALRGGAAGALELLSSESGSLHNSPTDSYLGSSRNSP 240

Query: 1232 GAGLQLEGEPMLTPSEGSDTSAAPLXXXXXXXXXXXXXXXXLKGGGALEKESHRRSYPLN 1291
            GAGLQLEGEPMLTPSEGSDTSAAPL                LKGGGALEKESHRRSYPLN
Sbjct: 241  GAGLQLEGEPMLTPSEGSDTSAAPLSEAGRAGQRRSASRDSLKGGGALEKESHRRSYPLN 300

Query: 1292 AASLNGAPKGGKYDDVTLMGAEVASGGCMKTGLWKSETTV 1331
            AASLNGAPKGGKYDDVTLMGAEVASGGCMKTGLWKSETTV
Sbjct: 301  AASLNGAPKGGKYDDVTLMGAEVASGGCMKTGLWKSETTV 340



>ref|XP_039194.1| (XM_039194) hypothetical protein FLJ14390 [Homo sapiens]
 dbj|BAB55022.1| (AK027296) unnamed protein product [Homo sapiens]
          Length = 185

 Score =  265 bits (669), Expect = 5e-69
 Identities = 135/149 (90%), Positives = 135/149 (90%)

Query: 30  CPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSXXXXXXXXXXXXXXNGTVTLLLSNNKI 89
           CPLSIRSCKCSGERPKGLSGGVPGPARRRVVCS              NGTVTLLLSNNKI
Sbjct: 37  CPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSGGDLPEPPEPGLLPNGTVTLLLSNNKI 96

Query: 90  TGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLP 149
           TGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLP
Sbjct: 97  TGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLP 156

Query: 150 RLLRLNISGNIFSSLQPGVFDELPALKVV 178
           RLLRLNISGNIFSSLQPGVFDELPALKVV
Sbjct: 157 RLLRLNISGNIFSSLQPGVFDELPALKVV 185



>gb|AAF48247.1| (AE003492) CG15744 gene product [Drosophila melanogaster]
          Length = 1797

 Score =  253 bits (640), Expect = 1e-65
 Identities = 226/904 (25%), Positives = 359/904 (39%), Gaps = 117/904 (12%)

Query: 106 LDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETF-QGLPRLLRLNISGNIFSSL 164
           ++   N I+ +    F    ELKRLDLS N +  L  +TF   L  L +L ++GN  S +
Sbjct: 88  INASKNSIALITAEDFRNFTELKRLDLSFNLLTELDKDTFGDSLAHLEKLKLAGNAISHI 147

Query: 165 QPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGS 224
             G FD++P LK++DL    L CDC L WL+ W+ +R ++L     C  P       L  
Sbjct: 148 YEGTFDQMPKLKLLDLSGNPLACDCGLIWLIAWSSSREVRLQPPPKCESPGNFRGMPLKK 207

Query: 225 LQEAQ-LCCEGALELHTHHLIPSLRQVVFQGDRLPFQCSASYLG---------------- 267
           L+  +   CE  L+     LIPS  QV F+GD L  +C A  +                 
Sbjct: 208 LRVGKDFHCETLLQ-PLLELIPSQNQVAFEGDELQLKCHAPRVAIGVPRESEDLPTKAYV 266

Query: 268 -----------NDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWAS 316
                      N T    Y +   V GD    + L      D   + S L ++ +    +
Sbjct: 267 FWGWSEKIRAKNSTEDIIYQDPTKVFGD----VNLETRHSTDSGILQSILRIASLTQNHT 322

Query: 317 GEWECTVSMAQGNASKKVEIVVLETSASYCPAERVANNRGDFRWPRTLAGITAYQSCLQY 376
           G W+CT+   Q N S+ + + V+     YC A  V  N+G + WPRT+ G T  Q C++ 
Sbjct: 323 GMWDCTLRSQQANLSQAIVLHVVAKGTLYCEARVVHTNKGTYHWPRTMRGETVLQECVEE 382

Query: 377 PFTSVPLGGGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFV---LMPINASNA 433
           P             RAS  C  +G W   D   C+Y ++ TR+L  F    L      NA
Sbjct: 383 P------SDATQARRASHECGPSGEWLNLDTESCVYVSETTRILEQFAKVNLTLTKGQNA 436

Query: 434 LTLAHQLRVYTAEAASFS---DMMDVVYVAQMIQKFLGYVD---QIKELVEVMVDMASNL 487
           L +A +L  +T      +   D MD+ Y+A+ + K+L  ++   Q +E+  +++D+ S L
Sbjct: 437 LEIARRLHNFTQAQTQLNRIRDPMDLEYIARTLVKYLDQLEQPQQQQEISHLLMDIVSQL 496

Query: 488 MLVDEHLLWLAQREDKACSRIVGALE--RIGGAALSPHAQHIS----------VNARNVA 535
           + +  HL   AQ E     R++  +E   +  A  S  A+ +              RN+ 
Sbjct: 497 LNLPAHLFRAAQSEQGTGQRLLHVVESSAMRLALASTQAEPLPAEMIPWRGSLAQQRNLF 556

Query: 536 LEAYLIKPHSYVGLTCTAFQRREGGVPGTRPGSPGQNXXXXXXXXADQQLRFRCTTGRPN 595
           +E + I   ++V L+C   ++   G                          F+C +    
Sbjct: 557 VEFFNISLDAFVSLSCVWLEQSPRG--------------------------FQCNSANDT 590

Query: 596 VSLSSFHIKNSVALASIQXXXXXXXXXXXXXXXXXXXDCTLQLLVFRNGRLF------HS 649
           + +   +    +  A                         L + + RNG+L       H+
Sbjct: 591 IPM---YEHGDIDAAIQLPYSVIGNSSTTLPATTTIRSLRLMISLHRNGKLLPNLRGSHN 647

Query: 650 HSNTSXXXXXXXXXXXXVATPVIFAGTSGCGVGNLTEPVAVSLR---HWAEGAEPVAAWW 706
            S +S             A                 + V V LR   +    + P  AWW
Sbjct: 648 ESLSSAIIGILAYSSDGEALQFRADNELDPEEDVYQQRVTVMLRAHPYHNPLSAPQPAWW 707

Query: 707 SQEGPGEAGGWTSEGCQLRSSQPNVSALHCQHLGNVAVLME---LSAFPREVGGAGAGLH 763
                 +   W +  CQ       +    C   G   +L     L+ F  E  GA    H
Sbjct: 708 D----ADEQRWETSVCQQHYQHRTLVMFSCSRTGYYGLLQRSQYLNDFRSEESGA-RFRH 762

Query: 764 P--VVYPXXXXXXXXXXXXXXTYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFAGGITL 821
           P   VY               T+ +   ++R++R   H L+N    +   +  F+ GI  
Sbjct: 763 PPAAVYAGCGLLFACCAFNAVTFAVFGRAVRINRVQRHALVNTWLALGALALAFSLGIYQ 822

Query: 822 TNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAP------PPQEGDPALPTP- 874
           T  Q  C+ +G+ +HY  L  LLW+ V    ++K LT          P Q+ +P      
Sbjct: 823 TASQPQCRLLGLLMHYLGLCVLLWVCVSLSSMYKRLTKTTTSGQGQCPGQDMEPQRERER 882

Query: 875 SPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALILLITWI 934
            P+L  YL+  GI L+ICGI++AVN+  Y  +  YC+L    +L A  +P  ++++   I
Sbjct: 883 KPILGIYLVGWGIALLICGISSAVNLAEYATYD-YCFLHSSTTLNALLVPAVILVIFCGI 941

Query: 935 YFLC 938
             LC
Sbjct: 942 LALC 945



>ref|XP_032373.2| (XM_032373) hypothetical protein XP_032373 [Homo sapiens]
          Length = 525

 Score =  228 bits (575), Expect = 5e-58
 Identities = 173/552 (31%), Positives = 234/552 (42%), Gaps = 47/552 (8%)

Query: 800  MLLNLCFHIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTW 859
            ML+NLCFHI +T  VF GGIT T    +CQAVGI LHYS+L+T+LW+GV AR ++K++T 
Sbjct: 1    MLVNLCFHIFLTCVVFVGGITQTRNASICQAVGIILHYSTLATVLWVGVTARNIYKQVTK 60

Query: 860  RAPPPQEGDPALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNY--RDHSPYCWLVWRPS 917
            +A   Q+ D   P P PMLRFYLI GGIP+I+CGITAA NI NY  R ++PYCW+ W PS
Sbjct: 61   KAKRCQDPDEPPPPPRPMLRFYLIGGGIPIIVCGITAAANIKNYGSRPNAPYCWMAWEPS 120

Query: 918  LGAFYIPVALILLITWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGSTRLRXXXX 977
            LGAFY P + I  +  +YFL   ++L+    ++P+        E  E      RL     
Sbjct: 121  LGAFYGPASFITFVNCMYFLSIFIQLK----RHPE-----RKYELKEPTEEQQRLAANEN 171

Query: 978  XXXXXXXXXATGSARVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRW 1037
                        S  + +    E+  + +S   QL     T  LY+A+W  GALAVS  +
Sbjct: 172  GEINHQDSM---SLSLISTSALENEHTFHS---QLLGASLTLLLYVALWMFGALAVSLYY 225

Query: 1038 LPRVVCSCLYGVAASALGLFVFTHHCARRRDVRXXXXXX--XXXXXXXXXXXXXXXXXXX 1095
               +V S ++G  + +   F   HHC  R DVR                           
Sbjct: 226  PLDLVFSFVFGATSLSFSAFFVVHHCVNREDVRLAWIMTCCPGRSSYSVQVNVQPPNSNG 285

Query: 1096 XEDGSPVFXXXXXXXXXXXXXXXXXXXXXXXCKLTNLQLAQSQVCXXXXXXXXXXXXXXX 1155
                +P                         CKLTNLQ A +Q                 
Sbjct: 286  TNGEAPKCPNSSAESSCTNKSASSFKNSSQGCKLTNLQAAAAQCHANSLPLNSTPQLDNS 345

Query: 1156 XTRGNL-----AHRHPNNVH-----HGRRAHKSRAKGHRAGEACGKNXXXXXXXXXXXXX 1205
             T  ++      H  P  V      H  R HK+R+KGHRA                    
Sbjct: 346  LTEHSMDNDIKMHVAPLEVQFRTNVHSSRHHKNRSKGHRASR---------LTVLREYAY 396

Query: 1206 XXXXXXXXXXHNSPTDSYLGSSR---NSPGAGLQLEGEPMLTPSEGSDTSAAPLXXXXXX 1262
                       N    S LG++     S  A L         P + S  + + L      
Sbjct: 397  DVPTSVEGSVQNGLPKSRLGNNEGHSRSRRAYLAYRERQYNPPQQDSSDACSTLPKSSRN 456

Query: 1263 X---XXXXXXXXXLKGGGALEKESHRRSYPLNAASLNGAPKGGKYDDVTLMGAEVASGGC 1319
                         L+    +E E+ ++SY LN A  NG  K    +   L+G +  S G 
Sbjct: 457  FEKPVSTTSKKDALRKPAVVELENQQKSYGLNLAIQNGPIKSNGQEG-PLLGTD--STGN 513

Query: 1320 MKTGLWKSETTV 1331
            ++TGLWK ETTV
Sbjct: 514  VRTGLWKHETTV 525



>dbj|BAB47457.1| (AB058731) KIAA1828 protein [Homo sapiens]
          Length = 496

 Score =  181 bits (454), Expect = 7e-44
 Identities = 107/252 (42%), Positives = 137/252 (53%), Gaps = 37/252 (14%)

Query: 831  VGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDPALPTPSPMLRFYLIAGGIPLI 890
            VGI LHYS+LST+LW+GV AR ++K++T +AP   + D       P+LRFYL++GG+P I
Sbjct: 22   VGIVLHYSTLSTMLWIGVTARNIYKQVTKKAPLCLDTDQPPYPRQPLLRFYLVSGGVPFI 81

Query: 891  ICGITAAVNIHNYR---DHSPYCWLVWRPSLGAFYIPVALILLITWIYFLCAGLRLRG-- 945
            ICG+TAA NI NY    + + YCW+ W PSLGAFY P A+I L+T +YFL   ++LR   
Sbjct: 82   ICGVTAATNIRNYGTEDEDTAYCWMAWEPSLGAFYGPAAIITLVTCVYFLGTYVQLRRHP 141

Query: 946  ----PLAQNPKAGNSRASLEAGEELRGSTRLRXXXXXXXXXXXXXATGSARVGTPGPPED 1001
                 L   P+     A+ E G  +R  T                         P     
Sbjct: 142  GRRYELRTQPEEQRRLATPEGGRGIRPGT------------------------PPAHDAP 177

Query: 1002 GDSL----YSPGVQLGALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAASALGLF 1057
            G S+    +S   QL A   T FL+ A WA GALAVSQ     +V SCLYG     LGLF
Sbjct: 178  GASVLQNEHSFQAQLRAAAFTLFLFTATWAFGALAVSQGHFLDMVFSCLYGAFCVTLGLF 237

Query: 1058 VFTHHCARRRDV 1069
            V  HHCA+R DV
Sbjct: 238  VLIHHCAKREDV 249



 Score = 39.1 bits (89), Expect = 0.46
 Identities = 31/91 (34%), Positives = 39/91 (42%), Gaps = 9/91 (9%)

Query: 1241 PMLTPSEGSDTSAAPLXXXXXXXXXXXXXXXXLKGGGALEKESHRRSYPLNAASLNGAPK 1300
            PM+T  EGSD S A                    G G LE     +S P    S NG PK
Sbjct: 415  PMVTQPEGSDGSPALYSCPTQPGREAAL------GPGHLEMLRRTQSLPFGGPSQNGLPK 468

Query: 1301 GGKYDDVTLMGAEVASGGCMKTGLWKSETTV 1331
            G   + +   G +    G ++TG WK+ETTV
Sbjct: 469  GKLLEGLP-FGTD--GTGNIRTGPWKNETTV 496



>ref|XP_039195.1| (XM_039195) hypothetical protein XP_039195 [Homo sapiens]
          Length = 246

 Score =  157 bits (394), Expect = 8e-37
 Identities = 77/94 (81%), Positives = 78/94 (82%)

Query: 1238 EGEPMLTPSEGSDTSAAPLXXXXXXXXXXXXXXXXLKGGGALEKESHRRSYPLNAASLNG 1297
            +GEPMLTPSEGSDTSAAPL                LKGGGALEKESHRRSYPLNAASLNG
Sbjct: 153  KGEPMLTPSEGSDTSAAPLSEAGRAGQRRSASRDSLKGGGALEKESHRRSYPLNAASLNG 212

Query: 1298 APKGGKYDDVTLMGAEVASGGCMKTGLWKSETTV 1331
            APKGGKYDDVTLMGAEVASGGCMKTGLWKSETTV
Sbjct: 213  APKGGKYDDVTLMGAEVASGGCMKTGLWKSETTV 246



>ref|XP_033711.1| (XM_033711) DKFZP586O1624 protein [Homo sapiens]
 ref|XP_033712.1| (XM_033712) DKFZP586O1624 protein [Homo sapiens]
          Length = 1093

 Score =  105 bits (260), Expect = 4e-21
 Identities = 75/262 (28%), Positives = 119/262 (44%), Gaps = 7/262 (2%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIIS-TVQP--GAFLGLGELKRLDLSNNRIG 138
           L LS+N I+ +  G+F GL  L  LDL +N IS T++   GAF GL  L +L L  N+I 
Sbjct: 336 LRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIK 395

Query: 139 CLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWA 198
            +    F GL  L  LN+ GN   S+Q   F ++  LK + + ++   CDC L+WL PW 
Sbjct: 396 SVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSDSFLCDCQLKWLPPWL 455

Query: 199 QNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRLP 258
             R LQ      CA+P +L  Q++ S+      C+  L+     +      +   G  + 
Sbjct: 456 IGRMLQAFVTATCAHPESLKGQSIFSVPPESFVCDDFLK--PQIITQPETTMAMVGKDIR 513

Query: 259 FQCS-ASYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWASG 317
           F CS AS   +     W  +   +   +    +   +   +    T+ L L  +     G
Sbjct: 514 FTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDGEVMEYTTILHLRQVTFGHEG 573

Query: 318 EWECTVSMAQGNA-SKKVEIVV 338
            ++C ++   G+  S K  + V
Sbjct: 574 RYQCVITNHFGSTYSHKARLTV 595



 Score = 51.2 bits (120), Expect = 1e-04
 Identities = 39/102 (38%), Positives = 51/102 (49%), Gaps = 2/102 (1%)

Query: 80  VTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           V+L L +NKI  +          LE LDL  N I+ V+   F     +K L+L+ NRIG 
Sbjct: 118 VSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGT 177

Query: 140 LTSETFQGLPR-LLRLNISGNIFSSLQPGVFDELPALKVVDL 180
           L    F GL R LL L +S N  + L    F +LP L  +DL
Sbjct: 178 LELGAFDGLSRSLLTLRLSKNRITQLPVRAF-KLPRLTQLDL 218



 Score = 50.0 bits (117), Expect = 2e-04
 Identities = 35/104 (33%), Positives = 50/104 (47%)

Query: 77  NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 136
           N    L L  N I+ L +G+F GLS +  L L  N +  V  G+  GL  L +L LSNN 
Sbjct: 235 NSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNS 294

Query: 137 IGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDL 180
           I  +  + +    +L  L +S N  + L      EL +L V+ L
Sbjct: 295 IARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRL 338



 Score = 47.6 bits (111), Expect = 0.001
 Identities = 40/121 (33%), Positives = 53/121 (43%), Gaps = 24/121 (19%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGE----------------- 126
           LS N IT +RN  F     +++L+L  N I T++ GAF GL                   
Sbjct: 146 LSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPV 205

Query: 127 -------LKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVD 179
                  L +LDL+ NRI  +   TFQGL  L  L +  N  S L  G F  L  + V+ 
Sbjct: 206 RAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLH 265

Query: 180 L 180
           L
Sbjct: 266 L 266



 Score = 45.7 bits (106), Expect = 0.005
 Identities = 28/76 (36%), Positives = 43/76 (55%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           L+ N+I  +   +F GL+ LE L L+ N IS +  GAF GL ++  L L  N +  + S 
Sbjct: 218 LNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSG 277

Query: 144 TFQGLPRLLRLNISGN 159
           +  GL  L +L++S N
Sbjct: 278 SLYGLTALHQLHLSNN 293



>gb|AAK62357.1|AF381545_1 (AF381545) membrane glycoprotein LIG-1 [Homo sapiens]
          Length = 1093

 Score =  105 bits (260), Expect = 4e-21
 Identities = 75/262 (28%), Positives = 119/262 (44%), Gaps = 7/262 (2%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIIS-TVQP--GAFLGLGELKRLDLSNNRIG 138
           L LS+N I+ +  G+F GL  L  LDL +N IS T++   GAF GL  L +L L  N+I 
Sbjct: 336 LRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIK 395

Query: 139 CLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWA 198
            +    F GL  L  LN+ GN   S+Q   F ++  LK + + ++   CDC L+WL PW 
Sbjct: 396 SVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSDSFLCDCQLKWLPPWL 455

Query: 199 QNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRLP 258
             R LQ      CA+P +L  Q++ S+      C+  L+     +      +   G  + 
Sbjct: 456 IGRMLQAFVTATCAHPESLKGQSIFSVPPESFVCDDFLK--PQIITQPETTMAMVGKDIR 513

Query: 259 FQCS-ASYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWASG 317
           F CS AS   +     W  +   +   +    +   +   +    T+ L L  +     G
Sbjct: 514 FTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDGEVMEYTTILHLRQVTFGHEG 573

Query: 318 EWECTVSMAQGNA-SKKVEIVV 338
            ++C ++   G+  S K  + V
Sbjct: 574 RYQCVITNHFGSTYSHKARLTV 595



 Score = 51.2 bits (120), Expect = 1e-04
 Identities = 39/102 (38%), Positives = 51/102 (49%), Gaps = 2/102 (1%)

Query: 80  VTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           V+L L +NKI  +          LE LDL  N I+ V+   F     +K L+L+ NRIG 
Sbjct: 118 VSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGT 177

Query: 140 LTSETFQGLPR-LLRLNISGNIFSSLQPGVFDELPALKVVDL 180
           L    F GL R LL L +S N  + L    F +LP L  +DL
Sbjct: 178 LELGAFDGLSRSLLTLRLSKNRITQLPVRAF-KLPRLTQLDL 218



 Score = 50.0 bits (117), Expect = 2e-04
 Identities = 35/104 (33%), Positives = 50/104 (47%)

Query: 77  NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 136
           N    L L  N I+ L +G+F GLS +  L L  N +  V  G+  GL  L +L LSNN 
Sbjct: 235 NSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNS 294

Query: 137 IGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDL 180
           I  +  + +    +L  L +S N  + L      EL +L V+ L
Sbjct: 295 IARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRL 338



 Score = 47.6 bits (111), Expect = 0.001
 Identities = 40/121 (33%), Positives = 53/121 (43%), Gaps = 24/121 (19%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGE----------------- 126
           LS N IT +RN  F     +++L+L  N I T++ GAF GL                   
Sbjct: 146 LSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPV 205

Query: 127 -------LKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVD 179
                  L +LDL+ NRI  +   TFQGL  L  L +  N  S L  G F  L  + V+ 
Sbjct: 206 RAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLH 265

Query: 180 L 180
           L
Sbjct: 266 L 266



 Score = 45.7 bits (106), Expect = 0.005
 Identities = 28/76 (36%), Positives = 43/76 (55%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           L+ N+I  +   +F GL+ LE L L+ N IS +  GAF GL ++  L L  N +  + S 
Sbjct: 218 LNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSG 277

Query: 144 TFQGLPRLLRLNISGN 159
           +  GL  L +L++S N
Sbjct: 278 SLYGLTALHQLHLSNN 293



>dbj|BAB40659.1| (AB050468) membrane glycoprotein LIG-1 [Homo sapiens]
          Length = 1094

 Score =  105 bits (260), Expect = 4e-21
 Identities = 75/262 (28%), Positives = 119/262 (44%), Gaps = 7/262 (2%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIIS-TVQP--GAFLGLGELKRLDLSNNRIG 138
           L LS+N I+ +  G+F GL  L  LDL +N IS T++   GAF GL  L +L L  N+I 
Sbjct: 336 LRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIK 395

Query: 139 CLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWA 198
            +    F GL  L  LN+ GN   S+Q   F ++  LK + + ++   CDC L+WL PW 
Sbjct: 396 SVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSDSFLCDCQLKWLPPWL 455

Query: 199 QNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRLP 258
             R LQ      CA+P +L  Q++ S+      C+  L+     +      +   G  + 
Sbjct: 456 IGRMLQAFVTATCAHPESLKGQSIFSVPPESFVCDDFLK--PQIITQPETTMAMVGKDIR 513

Query: 259 FQCS-ASYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWASG 317
           F CS AS   +     W  +   +   +    +   +   +    T+ L L  +     G
Sbjct: 514 FTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDGEVMEYTTILHLRQVTFGHEG 573

Query: 318 EWECTVSMAQGNA-SKKVEIVV 338
            ++C ++   G+  S K  + V
Sbjct: 574 RYQCVITNHFGSTYSHKARLTV 595



 Score = 51.2 bits (120), Expect = 1e-04
 Identities = 39/102 (38%), Positives = 51/102 (49%), Gaps = 2/102 (1%)

Query: 80  VTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           V+L L +NKI  +          LE LDL  N I+ V+   F     +K L+L+ NRIG 
Sbjct: 118 VSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGT 177

Query: 140 LTSETFQGLPR-LLRLNISGNIFSSLQPGVFDELPALKVVDL 180
           L    F GL R LL L +S N  + L    F +LP L  +DL
Sbjct: 178 LELGAFDGLSRSLLTLRLSKNRITQLPVRAF-KLPRLTQLDL 218



 Score = 50.0 bits (117), Expect = 2e-04
 Identities = 35/104 (33%), Positives = 50/104 (47%)

Query: 77  NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 136
           N    L L  N I+ L +G+F GLS +  L L  N +  V  G+  GL  L +L LSNN 
Sbjct: 235 NSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNS 294

Query: 137 IGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDL 180
           I  +  + +    +L  L +S N  + L      EL +L V+ L
Sbjct: 295 IARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRL 338



 Score = 47.6 bits (111), Expect = 0.001
 Identities = 40/121 (33%), Positives = 53/121 (43%), Gaps = 24/121 (19%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGE----------------- 126
           LS N IT +RN  F     +++L+L  N I T++ GAF GL                   
Sbjct: 146 LSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPV 205

Query: 127 -------LKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVD 179
                  L +LDL+ NRI  +   TFQGL  L  L +  N  S L  G F  L  + V+ 
Sbjct: 206 RAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLH 265

Query: 180 L 180
           L
Sbjct: 266 L 266



 Score = 45.7 bits (106), Expect = 0.005
 Identities = 28/76 (36%), Positives = 43/76 (55%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           L+ N+I  +   +F GL+ LE L L+ N IS +  GAF GL ++  L L  N +  + S 
Sbjct: 218 LNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSG 277

Query: 144 TFQGLPRLLRLNISGN 159
           +  GL  L +L++S N
Sbjct: 278 SLYGLTALHQLHLSNN 293



>ref|NP_032403.1| (NM_008377) integral membrane glycoprotein [Mus musculus]
 pir||A58532 glial cell membrane glycoprotein LIG-1 precursor - mouse
 dbj|BAA11416.1| (D78572) membrane glycoprotein [Mus musculus]
          Length = 1091

 Score =  104 bits (257), Expect = 9e-21
 Identities = 77/262 (29%), Positives = 118/262 (44%), Gaps = 7/262 (2%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIIS-TVQP--GAFLGLGELKRLDLSNNRIG 138
           L LS+N I+ +  G+F GL  L  LDL +N IS T++   GAF GL  L +L L  N+I 
Sbjct: 338 LRLSHNAISHIAEGAFKGLKSLRVLDLDHNEISGTIEDTSGAFTGLDNLSKLTLFGNKIK 397

Query: 139 CLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWA 198
            +    F GL  L  LN+  N   S+Q   F ++  LK + + +E   CDC L+WL PW 
Sbjct: 398 SVAKRAFSGLESLEHLNLGENAIRSVQFDAFAKMKNLKELYISSESFLCDCQLKWLPPWL 457

Query: 199 QNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRLP 258
             R LQ      CA+P +L  Q++ S+      C+   +        +   VV  G  + 
Sbjct: 458 MGRMLQAFVTATCAHPESLKGQSIFSVLPDSFVCDDFPKPQIITQPETTMAVV--GKDIR 515

Query: 259 FQCS-ASYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWASG 317
           F CS AS   +     W  +   +   +        +   +    T+ L L H+     G
Sbjct: 516 FTCSAASSSSSPMTFAWKKDNEVLANADMENFAHVRAQDGEVMEYTTILHLRHVTFGHEG 575

Query: 318 EWECTVSMAQGNA-SKKVEIVV 338
            ++C ++   G+  S K  + V
Sbjct: 576 RYQCIITNHFGSTYSHKARLTV 597



 Score = 54.7 bits (129), Expect = 9e-06
 Identities = 38/104 (36%), Positives = 54/104 (51%), Gaps = 2/104 (1%)

Query: 78  GTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRI 137
           G V+L L +NKI  +          LE LDL +N I+ ++   F     ++ L+L++NRI
Sbjct: 118 GVVSLFLQHNKILSVDGSQLKSYLSLEVLDLSSNNITEIRSSCFPNGLRIRELNLASNRI 177

Query: 138 GCLTSETFQGLPR-LLRLNISGNIFSSLQPGVFDELPALKVVDL 180
             L S  F GL R LL L +S N  + L    F +LP L  +DL
Sbjct: 178 SILESGAFDGLSRSLLTLRLSKNRITQLPVKAF-KLPRLTQLDL 220



 Score = 49.6 bits (116), Expect = 3e-04
 Identities = 40/100 (40%), Positives = 54/100 (54%), Gaps = 2/100 (2%)

Query: 82  LLLSNNKITGLRNGSFLGLSL-LEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 140
           L L++N+I+ L +G+F GLS  L  L L  N I+ +   AF  L  L +LDL+ NRI  +
Sbjct: 170 LNLASNRISILESGAFDGLSRSLLTLRLSKNRITQLPVKAFK-LPRLTQLDLNRNRIRLI 228

Query: 141 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDL 180
              TFQGL  L  L +  N  S L  G F  L  + V+ L
Sbjct: 229 EGLTFQGLDSLEVLRLQRNNISRLTDGAFWGLSKMHVLHL 268



 Score = 49.6 bits (116), Expect = 3e-04
 Identities = 40/123 (32%), Positives = 53/123 (42%), Gaps = 24/123 (19%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIG--- 138
           L L  N I+ L +G+F GLS +  L L  N +  V  G+  GL  L +L LSNN I    
Sbjct: 242 LRLQRNNISRLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSISRIQ 301

Query: 139 ------C---------------LTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKV 177
                 C               L  E+   L  L  L +S N  S +  G F  L +L+V
Sbjct: 302 RDGWSFCQKLHELILSFNNLTRLDEESLAELSSLSILRLSHNAISHIAEGAFKGLKSLRV 361

Query: 178 VDL 180
           +DL
Sbjct: 362 LDL 364



 Score = 48.0 bits (112), Expect = 0.001
 Identities = 30/82 (36%), Positives = 45/82 (54%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           L+ N+I  +   +F GL  LE L L+ N IS +  GAF GL ++  L L  N +  + S 
Sbjct: 220 LNRNRIRLIEGLTFQGLDSLEVLRLQRNNISRLTDGAFWGLSKMHVLHLEYNSLVEVNSG 279

Query: 144 TFQGLPRLLRLNISGNIFSSLQ 165
           +  GL  L +L++S N  S +Q
Sbjct: 280 SLYGLTALHQLHLSNNSISRIQ 301



>ref|NP_055628.1| (NM_014813) KIAA0806 gene product [Homo sapiens]
 ref|XP_001307.1| (XM_001307) KIAA0806 gene product [Homo sapiens]
 dbj|BAA34526.1| (AB018349) KIAA0806 protein [Homo sapiens]
          Length = 1065

 Score =  102 bits (252), Expect = 4e-20
 Identities = 82/267 (30%), Positives = 128/267 (47%), Gaps = 14/267 (5%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTV---QPGAFLGLGELKRLDLSNNRIG 138
           L L +N++T + +G F  LS L+ LDLRNN IS        AF GL  L +L L  N+I 
Sbjct: 340 LNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIK 399

Query: 139 CLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWA 198
            +T + F GL  L  L+++ N   S+Q   F +   LK + L T  L CDCHL+WLL W 
Sbjct: 400 SITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTH-LKELILNTSSLLCDCHLKWLLQWL 458

Query: 199 QNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGAL--ELHTH-HLIPSLRQVVFQGD 255
            + + Q S +  CA+P  L  Q++ ++      C+  L  ++ TH   I +LR     G 
Sbjct: 459 VDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQIRTHPETIIALR-----GM 513

Query: 256 RLPFQCSA-SYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVW 314
            +   C+A S   +     W  +   +   +    +       +    TS L L ++   
Sbjct: 514 NVTLTCTAVSSSDSPMSTVWRKDSEILYDVDTENFVRYWQQAGEALEYTSILHLFNVNFT 573

Query: 315 ASGEWECTVSMAQG-NASKKVEIVVLE 340
             G+++C V+   G N S+K ++ V E
Sbjct: 574 DEGKYQCIVTNHFGSNYSQKAKLTVNE 600



 Score = 58.6 bits (139), Expect = 6e-07
 Identities = 36/104 (34%), Positives = 52/104 (49%)

Query: 77  NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 136
           N    L L +N +T +  G   GL +L++L +  N I  + P A+     L  LDLS N+
Sbjct: 263 NNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQ 322

Query: 137 IGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDL 180
           +  L    F GL  L RLN+  N  + +  GVF  L  L+ +DL
Sbjct: 323 LTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDL 366



 Score = 56.2 bits (133), Expect = 3e-06
 Identities = 33/106 (31%), Positives = 61/106 (57%)

Query: 81  TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 140
           +L +  N I+ L++G+F GL+ +E+L+L +N ++ V  G   GL  L++L +S N I  +
Sbjct: 243 SLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERI 302

Query: 141 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLT 186
           + + ++   RL  L++S N  + L    F  L  L+ ++LG   +T
Sbjct: 303 SPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVT 348



 Score = 52.7 bits (124), Expect = 4e-05
 Identities = 32/105 (30%), Positives = 51/105 (48%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L  N+I  +   +F GL  L  L ++ N IS ++ GAF GL  ++ L+L +N +  + 
Sbjct: 220 LELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVN 279

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLT 186
                GL  L +L +S N    + P  ++    L  +DL    LT
Sbjct: 280 KGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLT 324



 Score = 51.5 bits (121), Expect = 8e-05
 Identities = 45/130 (34%), Positives = 64/130 (48%), Gaps = 3/130 (2%)

Query: 82  LLLSNNKITGLRNGSFLGLSL-LEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 140
           L LSNN+IT L  G F  LS  L  + L  N +S + P  F  L  L+ L+L  NRI  +
Sbjct: 172 LNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIV 230

Query: 141 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQN 200
              TFQGL  L  L +  N  S L+ G F  L  ++ ++L    LT   +  WL      
Sbjct: 231 EGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLT-RVNKGWLYGLRML 289

Query: 201 RSLQLSEHTL 210
           + L +S++ +
Sbjct: 290 QQLYVSQNAI 299



 Score = 47.6 bits (111), Expect = 0.001
 Identities = 38/103 (36%), Positives = 59/103 (56%), Gaps = 4/103 (3%)

Query: 80  VTLL-LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIG 138
           +TLL L +N I  +   +      LE LDL +NIIS ++  +F  + +LK L+LSNNRI 
Sbjct: 122 ITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRM-QLKYLNLSNNRIT 180

Query: 139 CLTSETFQGL-PRLLRLNISGNIFSSLQPGVFDELPALKVVDL 180
            L +  F  L   LL + ++ N  S + P +F +LP L+ ++L
Sbjct: 181 TLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIF-KLPHLQFLEL 222



>ref|NP_476729.1| (NM_057381) sli-P2 [Drosophila melanogaster]
          Length = 1469

 Score =  100 bits (247), Expect = 1e-19
 Identities = 56/156 (35%), Positives = 83/156 (52%), Gaps = 1/156 (0%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L++N+I  +   SF  L  LE+LD+ NN+I+TV    F G   L+ L L NN+I CL 
Sbjct: 129 LQLTDNQIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLD 188

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+GL  L  L ++ N  +SL   +F  L  L+ + L      CDCHL WL  + ++ 
Sbjct: 189 EHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRS- 247

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALE 237
           + +L+ +T C  PS L  Q +  L + +  C G  E
Sbjct: 248 ATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTE 283



 Score = 90.1 bits (220), Expect = 2e-16
 Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 1/149 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN I+ + + +  GL  L  L L  N I  +  G F GLG L+ L L+ N I C+  +
Sbjct: 353 LSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEISCIRKD 412

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            F+ L  L  L++  N   SL  G FD + ++K V L      CDC+LRWL  +     +
Sbjct: 413 AFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHLAKNPFICDCNLRWLADYLHKNPI 472

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCC 232
           + S    C  P  +H + + SL+E +  C
Sbjct: 473 ETS-GARCESPKRMHRRRIESLREEKFKC 500



 Score = 85.8 bits (209), Expect = 4e-15
 Identities = 47/155 (30%), Positives = 81/155 (51%), Gaps = 2/155 (1%)

Query: 79  TVTLLLSNNKITGLRNGSFLG-LSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRI 137
           T  LLL++N++  + +    G L  L KL+L+ N ++ ++P AF G   ++ L L  N+I
Sbjct: 548 TTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKI 607

Query: 138 GCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPW 197
             ++++ F GL +L  LN+  N  S + PG F+ L +L  ++L +    C+CHL W   W
Sbjct: 608 KEISNKMFLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEW 667

Query: 198 AQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCC 232
            + +SL       C  PS +    +  L  ++  C
Sbjct: 668 LRKKSLN-GGAARCGAPSKVRDVQIKDLPHSEFKC 701



 Score = 76.1 bits (184), Expect = 3e-12
 Identities = 50/158 (31%), Positives = 74/158 (46%), Gaps = 5/158 (3%)

Query: 79  TVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIG 138
           T  L L +N+I  +       L  L +LDL NN I+ +    F  L +L  L +S N++ 
Sbjct: 744 TSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQ 803

Query: 139 CLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWA 198
           CL      GL  L  L++ GN  S L  G F++L +L  + LG+  L CDC L+W   W 
Sbjct: 804 CLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWI 863

Query: 199 QNRSLQLSEHTL--CAYPSALHAQALGSLQEAQLCCEG 234
           +   L   E  +  CA P  +  + + S   +   C G
Sbjct: 864 K---LDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRG 898



>ref|NP_476728.1| (NM_057380) sli-P1 [Drosophila melanogaster]
 gb|AAF58098.1| (AE003809) sli gene product [alt 2] [Drosophila melanogaster]
          Length = 1480

 Score =  100 bits (247), Expect = 1e-19
 Identities = 56/156 (35%), Positives = 83/156 (52%), Gaps = 1/156 (0%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L++N+I  +   SF  L  LE+LD+ NN+I+TV    F G   L+ L L NN+I CL 
Sbjct: 129 LQLTDNQIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLD 188

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+GL  L  L ++ N  +SL   +F  L  L+ + L      CDCHL WL  + ++ 
Sbjct: 189 EHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRS- 247

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALE 237
           + +L+ +T C  PS L  Q +  L + +  C G  E
Sbjct: 248 ATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTE 283



 Score = 90.1 bits (220), Expect = 2e-16
 Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 1/149 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN I+ + + +  GL  L  L L  N I  +  G F GLG L+ L L+ N I C+  +
Sbjct: 353 LSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEISCIRKD 412

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            F+ L  L  L++  N   SL  G FD + ++K V L      CDC+LRWL  +     +
Sbjct: 413 AFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHLAKNPFICDCNLRWLADYLHKNPI 472

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCC 232
           + S    C  P  +H + + SL+E +  C
Sbjct: 473 ETS-GARCESPKRMHRRRIESLREEKFKC 500



 Score = 85.8 bits (209), Expect = 4e-15
 Identities = 47/155 (30%), Positives = 81/155 (51%), Gaps = 2/155 (1%)

Query: 79  TVTLLLSNNKITGLRNGSFLG-LSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRI 137
           T  LLL++N++  + +    G L  L KL+L+ N ++ ++P AF G   ++ L L  N+I
Sbjct: 548 TTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKI 607

Query: 138 GCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPW 197
             ++++ F GL +L  LN+  N  S + PG F+ L +L  ++L +    C+CHL W   W
Sbjct: 608 KEISNKMFLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEW 667

Query: 198 AQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCC 232
            + +SL       C  PS +    +  L  ++  C
Sbjct: 668 LRKKSLN-GGAARCGAPSKVRDVQIKDLPHSEFKC 701



 Score = 76.1 bits (184), Expect = 3e-12
 Identities = 50/158 (31%), Positives = 74/158 (46%), Gaps = 5/158 (3%)

Query: 79  TVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIG 138
           T  L L +N+I  +       L  L +LDL NN I+ +    F  L +L  L +S N++ 
Sbjct: 744 TSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQ 803

Query: 139 CLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWA 198
           CL      GL  L  L++ GN  S L  G F++L +L  + LG+  L CDC L+W   W 
Sbjct: 804 CLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWI 863

Query: 199 QNRSLQLSEHTL--CAYPSALHAQALGSLQEAQLCCEG 234
           +   L   E  +  CA P  +  + + S   +   C G
Sbjct: 864 K---LDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRG 898



>prf||1704200A slit gene [Drosophila sp.]
          Length = 1480

 Score =  100 bits (247), Expect = 1e-19
 Identities = 56/156 (35%), Positives = 83/156 (52%), Gaps = 1/156 (0%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L++N+I  +   SF  L  LE+LD+ NN+I+TV    F G   L+ L L NN+I CL 
Sbjct: 129 LQLTDNQIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLD 188

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+GL  L  L ++ N  +SL   +F  L  L+ + L      CDCHL WL  + ++ 
Sbjct: 189 EHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRS- 247

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALE 237
           + +L+ +T C  PS L  Q +  L + +  C G  E
Sbjct: 248 ATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTE 283



 Score = 91.7 bits (224), Expect = 7e-17
 Identities = 52/150 (34%), Positives = 76/150 (50%), Gaps = 1/150 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN I+ + + +  GL  L  L L  N I  +  G F GLG L+ L L+ N I C+  +
Sbjct: 353 LSNNNISRIAHDALSGLKQLTTLVLYGNKIFDLPSGVFKGLGSLRLLLLNANEISCIRKD 412

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            F+ L  L  L++  N   SL  G FD + ++K V L      CDC+LRWL  +     +
Sbjct: 413 AFRDLHSLSLLSLYDNNIQSLANGTFDAMKSMKTVHLAKNPFICDCNLRWLADYLHKNPI 472

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCE 233
           + S    C  P  +H + + SL+E +  CE
Sbjct: 473 ETS-GARCESPKRMHRRRIESLREEKFKCE 501



 Score = 80.8 bits (196), Expect = 1e-13
 Identities = 46/155 (29%), Positives = 80/155 (50%), Gaps = 2/155 (1%)

Query: 79  TVTLLLSNNKITGLRNGSFLG-LSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRI 137
           T  LLL++N++  + +    G L  L KL+L+ N ++ ++P AF G   ++ L L  N+I
Sbjct: 548 TTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKI 607

Query: 138 GCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPW 197
             ++++ F GL +L  LN+  N  S + PG F+ L +L  ++L +    C+CHL W    
Sbjct: 608 KEISNKMFLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEC 667

Query: 198 AQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCC 232
            + +SL       C  PS +    +  L  ++  C
Sbjct: 668 VRKKSLN-GGAARCGAPSKVRDVDIKDLPHSEFKC 701



 Score = 74.9 bits (181), Expect = 8e-12
 Identities = 49/158 (31%), Positives = 74/158 (46%), Gaps = 5/158 (3%)

Query: 79  TVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIG 138
           T  L L +N+I  +       L  L +LDL NN I+ +    F  L +L  L +S N++ 
Sbjct: 744 TSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQ 803

Query: 139 CLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWA 198
           CL      GL  L  +++ GN  S L  G F++L +L  + LG+  L CDC L+W   W 
Sbjct: 804 CLQRHALSGLNNLRVVSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWI 863

Query: 199 QNRSLQLSEHTL--CAYPSALHAQALGSLQEAQLCCEG 234
           +   L   E  +  CA P  +  + + S   +   C G
Sbjct: 864 K---LDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRG 898



>pir||B36665 slit protein 2 precursor - fruit fly (Drosophila melanogaster)
          Length = 1469

 Score =  100 bits (247), Expect = 1e-19
 Identities = 56/156 (35%), Positives = 83/156 (52%), Gaps = 1/156 (0%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L++N+I  +   SF  L  LE+LD+ NN+I+TV    F G   L+ L L NN+I CL 
Sbjct: 129 LQLTDNQIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLD 188

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+GL  L  L ++ N  +SL   +F  L  L+ + L      CDCHL WL  + ++ 
Sbjct: 189 EHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRS- 247

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALE 237
           + +L+ +T C  PS L  Q +  L + +  C G  E
Sbjct: 248 ATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTE 283



 Score = 90.5 bits (221), Expect = 2e-16
 Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 1/149 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN I+ + + +  GL  L  L L  N I  +  G F GLG L+ L L+ N I C+  +
Sbjct: 353 LSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLRLLLLNANEISCIRKD 412

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            F+ L  L  L++  N   SL  G FD + ++K V L      CDC+LRWL  +     +
Sbjct: 413 AFRDLHSLSLLSLYDNNIQSLANGTFDAMKSMKTVHLAKNPFICDCNLRWLADYLHKNPI 472

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCC 232
           + S    C  P  +H + + SL+E +  C
Sbjct: 473 ETS-GARCESPKRMHRRRIESLREEKFKC 500



 Score = 81.1 bits (197), Expect = 1e-13
 Identities = 46/155 (29%), Positives = 80/155 (50%), Gaps = 2/155 (1%)

Query: 79  TVTLLLSNNKITGLRNGSFLG-LSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRI 137
           T  LLL++N++  + +    G L  L KL+L+ N ++ ++P AF G   ++ L L  N+I
Sbjct: 548 TTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKI 607

Query: 138 GCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPW 197
             ++++ F GL +L  LN+  N  S + PG F+ L +L  ++L +    C+CHL W    
Sbjct: 608 KEISNKMFLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEC 667

Query: 198 AQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCC 232
            + +SL       C  PS +    +  L  ++  C
Sbjct: 668 VRKKSLN-GGAARCGAPSKVRDVQIKDLPHSEFKC 701



 Score = 74.9 bits (181), Expect = 8e-12
 Identities = 49/158 (31%), Positives = 74/158 (46%), Gaps = 5/158 (3%)

Query: 79  TVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIG 138
           T  L L +N+I  +       L  L +LDL NN I+ +    F  L +L  L +S N++ 
Sbjct: 744 TSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQ 803

Query: 139 CLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWA 198
           CL      GL  L  +++ GN  S L  G F++L +L  + LG+  L CDC L+W   W 
Sbjct: 804 CLQRHALSGLNNLRVVSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWI 863

Query: 199 QNRSLQLSEHTL--CAYPSALHAQALGSLQEAQLCCEG 234
           +   L   E  +  CA P  +  + + S   +   C G
Sbjct: 864 K---LDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRG 898



>sp|P24014|SLIT_DROME SLIT PROTEIN PRECURSOR
 pir||A36665 slit protein 1 precursor - fruit fly (Drosophila melanogaster)
 emb|CAA37910.1| (X53959) slit protein [Drosophila melanogaster]
          Length = 1480

 Score =  100 bits (247), Expect = 1e-19
 Identities = 56/156 (35%), Positives = 83/156 (52%), Gaps = 1/156 (0%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L++N+I  +   SF  L  LE+LD+ NN+I+TV    F G   L+ L L NN+I CL 
Sbjct: 129 LQLTDNQIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLD 188

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+GL  L  L ++ N  +SL   +F  L  L+ + L      CDCHL WL  + ++ 
Sbjct: 189 EHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRS- 247

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALE 237
           + +L+ +T C  PS L  Q +  L + +  C G  E
Sbjct: 248 ATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTE 283



 Score = 90.5 bits (221), Expect = 2e-16
 Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 1/149 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN I+ + + +  GL  L  L L  N I  +  G F GLG L+ L L+ N I C+  +
Sbjct: 353 LSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLRLLLLNANEISCIRKD 412

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            F+ L  L  L++  N   SL  G FD + ++K V L      CDC+LRWL  +     +
Sbjct: 413 AFRDLHSLSLLSLYDNNIQSLANGTFDAMKSMKTVHLAKNPFICDCNLRWLADYLHKNPI 472

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCC 232
           + S    C  P  +H + + SL+E +  C
Sbjct: 473 ETS-GARCESPKRMHRRRIESLREEKFKC 500



 Score = 81.1 bits (197), Expect = 1e-13
 Identities = 46/155 (29%), Positives = 80/155 (50%), Gaps = 2/155 (1%)

Query: 79  TVTLLLSNNKITGLRNGSFLG-LSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRI 137
           T  LLL++N++  + +    G L  L KL+L+ N ++ ++P AF G   ++ L L  N+I
Sbjct: 548 TTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKI 607

Query: 138 GCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPW 197
             ++++ F GL +L  LN+  N  S + PG F+ L +L  ++L +    C+CHL W    
Sbjct: 608 KEISNKMFLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEC 667

Query: 198 AQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCC 232
            + +SL       C  PS +    +  L  ++  C
Sbjct: 668 VRKKSLN-GGAARCGAPSKVRDVQIKDLPHSEFKC 701



 Score = 74.9 bits (181), Expect = 8e-12
 Identities = 49/158 (31%), Positives = 74/158 (46%), Gaps = 5/158 (3%)

Query: 79  TVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIG 138
           T  L L +N+I  +       L  L +LDL NN I+ +    F  L +L  L +S N++ 
Sbjct: 744 TSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQ 803

Query: 139 CLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWA 198
           CL      GL  L  +++ GN  S L  G F++L +L  + LG+  L CDC L+W   W 
Sbjct: 804 CLQRHALSGLNNLRVVSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWI 863

Query: 199 QNRSLQLSEHTL--CAYPSALHAQALGSLQEAQLCCEG 234
           +   L   E  +  CA P  +  + + S   +   C G
Sbjct: 864 K---LDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRG 898



>gb|AAF58053.1| (AE003808) CG8434 gene product [Drosophila melanogaster]
          Length = 1173

 Score =  100 bits (246), Expect = 2e-19
 Identities = 72/266 (27%), Positives = 122/266 (45%), Gaps = 20/266 (7%)

Query: 81  TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTV-----QPGAFLGLGELKRLDLSNN 135
           TL L++N++  L+  +F  +  LE+L+LR N +S +         F GL +L+RLDL  N
Sbjct: 516 TLNLAHNRLQYLQENTFDCVKNLEELNLRRNRLSWIIEDQSAAAPFKGLRKLRRLDLHGN 575

Query: 136 RIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLL 195
            +  ++++   GL  L  LN+  N  +S+Q   F+ +  L  +   +    CDC L W  
Sbjct: 576 NLKQISTKAMSGLNNLEILNLGSNALASIQVNAFEHMLRLNKLVFKSLNFICDCDLVWFQ 635

Query: 196 PWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGD 255
            W +NR  Q +EH +C YP  L  + L SL  ++L C  + +         +  V     
Sbjct: 636 QWLKNRFPQQAEHAVCGYPEHLLDRHLKSLSSSELVCVDSPKPRVEQEPDDMLAV--NAA 693

Query: 256 RLPFQCSAS-------YLGNDTRIRWYHN------RAPVEGDEQAGILLAESLIHDCTFI 302
            +  +C AS          ++ +I+W H+      R  V         +   L  + T I
Sbjct: 694 NITLECIASSPTAASLAAADELKIKWRHDNQHVQERPAVHDGASTETQIRHDLSTNQTSI 753

Query: 303 TSELTLSHIGVWASGEWECTVSMAQG 328
              L L+++   ++G ++C VS A G
Sbjct: 754 YGYLRLTNVTYESAGRYQCVVSNAFG 779



 Score = 62.8 bits (150), Expect = 3e-08
 Identities = 38/104 (36%), Positives = 59/104 (56%), Gaps = 1/104 (0%)

Query: 77  NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 136
           N  V L+LS N+IT +   SF  L+ L  L+L NN +ST+    F  L +LK+L L+ N+
Sbjct: 345 NNLVHLILSFNEITNVNEHSFATLNNLTDLELSNNRLSTLPIRVFKNLNQLKKLALNFNQ 404

Query: 137 IGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDL 180
           +  +   TF+GL  +  L +  N   +LQ GVF  +  ++ +DL
Sbjct: 405 LE-INWSTFRGLESMKNLQLKSNKIRALQDGVFYVMHKIETIDL 447



 Score = 54.7 bits (129), Expect = 9e-06
 Identities = 36/121 (29%), Positives = 62/121 (50%), Gaps = 7/121 (5%)

Query: 96  SFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLN 155
           +F GL  ++ L L++N I  +Q G F  + +++ +DL+ N+I  L+ +    L +L  LN
Sbjct: 411 TFRGLESMKNLQLKSNKIRALQDGVFYVMHKIETIDLAMNQISSLSRQGLFNLTKLRHLN 470

Query: 156 ISGNIFSSLQPGVFDELPALKVVDLGTEFLT------CDC-HLRWLLPWAQNRSLQLSEH 208
           +S N  S ++   ++   +L+V+DL    +        DC H    L  A NR   L E+
Sbjct: 471 LSFNAISRIEVDTWEFTQSLEVLDLSNNAINEFKPQHLDCLHRLKTLNLAHNRLQYLQEN 530

Query: 209 T 209
           T
Sbjct: 531 T 531



 Score = 53.5 bits (126), Expect = 2e-05
 Identities = 37/104 (35%), Positives = 51/104 (48%)

Query: 77  NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 136
           +G   L+L+NN IT + + S   L LL  LDL  N + T++  +F     L  L LS N 
Sbjct: 297 SGLKHLVLANNHITSISSESLAALPLLRTLDLSRNKLHTIELNSFPKSNNLVHLILSFNE 356

Query: 137 IGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDL 180
           I  +   +F  L  L  L +S N  S+L   VF  L  LK + L
Sbjct: 357 ITNVNEHSFATLNNLTDLELSNNRLSTLPIRVFKNLNQLKKLAL 400



 Score = 51.2 bits (120), Expect = 1e-04
 Identities = 32/99 (32%), Positives = 53/99 (53%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L +NKI  L++G F  +  +E +DL  N IS++       L +L+ L+LS N I  + 
Sbjct: 421 LQLKSNKIRALQDGVFYVMHKIETIDLAMNQISSLSRQGLFNLTKLRHLNLSFNAISRIE 480

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDL 180
            +T++    L  L++S N  +  +P   D L  LK ++L
Sbjct: 481 VDTWEFTQSLEVLDLSNNAINEFKPQHLDCLHRLKTLNL 519



 Score = 48.4 bits (113), Expect = 7e-04
 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 2/89 (2%)

Query: 81  TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 140
           TL L+NNK+          L  L K+ L+ N++  +    F+GL  LK L L+NN I  +
Sbjct: 255 TLHLANNKLNDTTVLEIRNLLNLTKVSLKRNLLEVIP--KFIGLSGLKHLVLANNHITSI 312

Query: 141 TSETFQGLPRLLRLNISGNIFSSLQPGVF 169
           +SE+   LP L  L++S N   +++   F
Sbjct: 313 SSESLAALPLLRTLDLSRNKLHTIELNSF 341



 Score = 45.3 bits (105), Expect = 0.006
 Identities = 32/100 (32%), Positives = 49/100 (49%)

Query: 81  TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 140
           T+ L+ N+I+ L       L+ L  L+L  N IS ++   +     L+ LDLSNN I   
Sbjct: 444 TIDLAMNQISSLSRQGLFNLTKLRHLNLSFNAISRIEVDTWEFTQSLEVLDLSNNAINEF 503

Query: 141 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDL 180
             +    L RL  LN++ N    LQ   FD +  L+ ++L
Sbjct: 504 KPQHLDCLHRLKTLNLAHNRLQYLQENTFDCVKNLEELNL 543



 Score = 40.6 bits (93), Expect = 0.16
 Identities = 32/109 (29%), Positives = 54/109 (49%), Gaps = 5/109 (4%)

Query: 83  LLSNNKITGLRN-----GSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRI 137
           LL+  K++  RN       F+GLS L+ L L NN I+++   +   L  L+ LDLS N++
Sbjct: 274 LLNLTKVSLKRNLLEVIPKFIGLSGLKHLVLANNHITSISSESLAALPLLRTLDLSRNKL 333

Query: 138 GCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLT 186
             +   +F     L+ L +S N  +++    F  L  L  ++L    L+
Sbjct: 334 HTIELNSFPKSNNLVHLILSFNEITNVNEHSFATLNNLTDLELSNNRLS 382



>gb|AAD44758.1|AF144627_1 (AF144627) SLIT1 [Mus musculus]
          Length = 1531

 Score = 96.3 bits (236), Expect = 3e-18
 Identities = 51/154 (33%), Positives = 83/154 (53%), Gaps = 1/154 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNNK++ + +G+F G + + +L L  N + +++ G F GL  L+ L L NNRI C+ ++
Sbjct: 572 LSNNKVSEIEDGTFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 631

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           +F GL  +  L++  N  +++ PG FD L AL  ++L      C+CHL WL  W + R +
Sbjct: 632 SFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTLNLLANPFNCNCHLSWLGDWLRKRKI 691

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEGALE 237
            ++ +  C  P  L    L  +      CE   E
Sbjct: 692 -VTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQE 724



 Score = 87.4 bits (213), Expect = 1e-15
 Identities = 48/153 (31%), Positives = 74/153 (47%), Gaps = 1/153 (0%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L+ N++  L    F     L +LDL  N +  V   AF G  +LK L L  NRI C+ 
Sbjct: 114 LRLNRNQLQVLPELLFQNNQALSRLDLSENFLQAVPRKAFRGATDLKNLQLDKNRISCIE 173

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+ L  L  L ++ N  +++    F+ +P L+   L +  L CDCHL WL  W + R
Sbjct: 174 EGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQR 233

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
              +   T C+ P++L    +  +Q+ +  C G
Sbjct: 234 P-TIGLFTQCSGPASLRGLNVAEVQKGEFSCSG 265



 Score = 81.1 bits (197), Expect = 1e-13
 Identities = 48/149 (32%), Positives = 75/149 (50%), Gaps = 1/149 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN+I  +   +F GL  L  L L  N I+ +  G F GL  L+ L L+ N+I C+  +
Sbjct: 340 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 399

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            FQ L  L  L++  N   SL  G F  L A++ + L      CDC+L+WL  + +   +
Sbjct: 400 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPI 459

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCC 232
           + +    CA P  L  + +G ++  +  C
Sbjct: 460 E-TTGARCASPRRLANKRIGQIKSKKFRC 487



 Score = 78.0 bits (189), Expect = 9e-13
 Identities = 49/153 (32%), Positives = 75/153 (48%), Gaps = 2/153 (1%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L  N+ T L  G       L+ +DL NN IS++   +F  + +L  L LS N + C+ 
Sbjct: 766 LYLDGNQFT-LVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIP 824

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              FQ L  L  L++ GN  S+LQ G+F ++ +L  + +G   L CDC LRWL  W +  
Sbjct: 825 PLAFQRLRSLRLLSLHGNDVSTLQEGIFADVTSLSHLAIGANPLYCDCRLRWLSSWVKT- 883

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
             +      CA P  +  + L +    +  C+G
Sbjct: 884 GYKEPGIARCAGPPEMEGKLLLTTPAKKFECQG 916



>ref|XP_039760.1| (XM_039760) Melanoma associated gene [Homo sapiens]
 ref|XP_056455.1| (XM_056455) Melanoma associated gene [Homo sapiens]
          Length = 1477

 Score = 95.2 bits (233), Expect = 6e-18
 Identities = 91/304 (29%), Positives = 141/304 (45%), Gaps = 41/304 (13%)

Query: 81  TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 140
           TLLL+NN+I  + +G+F  L  L+ L L  N I ++   AF GL  L++L L  N+I  L
Sbjct: 90  TLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETL 149

Query: 141 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLL----P 196
             ++FQ LP+L RL +  N  + L PG F+ L ++K + L +  L CDC + WL      
Sbjct: 150 DPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTLHCDCEILWLADLLKT 209

Query: 197 WAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQ--VVFQG 254
           +A++ + Q +   +C YP  +  +++ ++   +L CE          I S  Q   V  G
Sbjct: 210 YAESGNAQAA--AICEYPRRIQGRSVATITPEELNCE-------RPRITSEPQDADVTSG 260

Query: 255 DRLPFQCSASYLGN-DTRIRWY--HNRAPVEGDEQAGILLAESL-----------IHDC- 299
           + + F C A   GN    I W   +N   ++ D +  +L   +L           I+ C 
Sbjct: 261 NTVYFTCRAE--GNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCM 318

Query: 300 ------TFITSELTLSHIGVWASGEWECTVSMAQGNASKKVEIVVLETSASYCPAERVAN 353
                    T E+TL + G  A   +   V   Q       E V LE SA+  P  R++ 
Sbjct: 319 AKNVAGEVKTQEVTLRYFGSPARPTF---VIQPQNTEVLVGESVTLECSATGHPPPRISW 375

Query: 354 NRGD 357
            RGD
Sbjct: 376 TRGD 379



>dbj|BAA13219.1| (D86983) similar to D.melanogaster peroxidasin(U11052) [Homo
           sapiens]
 gb|AAF06354.1|AF200348_1 (AF200348) melanoma-associated antigen MG50 [Homo sapiens]
          Length = 1496

 Score = 95.2 bits (233), Expect = 6e-18
 Identities = 91/304 (29%), Positives = 141/304 (45%), Gaps = 41/304 (13%)

Query: 81  TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 140
           TLLL+NN+I  + +G+F  L  L+ L L  N I ++   AF GL  L++L L  N+I  L
Sbjct: 107 TLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETL 166

Query: 141 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLL----P 196
             ++FQ LP+L RL +  N  + L PG F+ L ++K + L +  L CDC + WL      
Sbjct: 167 DPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTLHCDCEILWLADLLKT 226

Query: 197 WAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQ--VVFQG 254
           +A++ + Q +   +C YP  +  +++ ++   +L CE          I S  Q   V  G
Sbjct: 227 YAESGNAQAA--AICEYPRRIQGRSVATITPEELNCE-------RPRITSEPQDADVTSG 277

Query: 255 DRLPFQCSASYLGN-DTRIRWY--HNRAPVEGDEQAGILLAESL-----------IHDC- 299
           + + F C A   GN    I W   +N   ++ D +  +L   +L           I+ C 
Sbjct: 278 NTVYFTCRAE--GNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCM 335

Query: 300 ------TFITSELTLSHIGVWASGEWECTVSMAQGNASKKVEIVVLETSASYCPAERVAN 353
                    T E+TL + G  A   +   V   Q       E V LE SA+  P  R++ 
Sbjct: 336 AKNVAGEVKTQEVTLRYFGSPARPTF---VIQPQNTEVLVGESVTLECSATGHPPPRISW 392

Query: 354 NRGD 357
            RGD
Sbjct: 393 TRGD 396



>ref|XP_047964.2| (XM_047964) slit (Drosophila) homolog 3 [Homo sapiens]
          Length = 1225

 Score = 94.4 bits (231), Expect = 1e-17
 Identities = 52/151 (34%), Positives = 82/151 (53%), Gaps = 1/151 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNNKI  +R G+F G + +++L L  N + TV    F GL  LK L L +N IGC++++
Sbjct: 266 LSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSND 325

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           TF GL  +  L++  N  +++ PG F  L +L  ++L +    C+CHL WL  W + R +
Sbjct: 326 TFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRI 385

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
            +S +  C  P  L    +  +      C+G
Sbjct: 386 -VSGNPRCQKPFFLKEIPIQDVAIQDFTCDG 415



 Score = 83.9 bits (204), Expect = 2e-14
 Identities = 47/152 (30%), Positives = 78/152 (50%), Gaps = 1/152 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           +S N+I+ +   +F GL  L  L L  N I+ +  G F GL  L+ L L+ N+I CL   
Sbjct: 40  ISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIVKGLFDGLVSLQLLLLNANKINCLRVN 99

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           TFQ L  L  L++  N   ++  G+F  L +++ + L      CDCHL+WL  + Q+  +
Sbjct: 100 TFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPI 159

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEGA 235
           + S    C+ P  L  + +  ++  +  C G+
Sbjct: 160 ETS-GARCSSPRRLANKRISQIKSKKFRCSGS 190



 Score = 76.5 bits (185), Expect = 3e-12
 Identities = 50/158 (31%), Positives = 75/158 (46%), Gaps = 2/158 (1%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L  N +T +       L  L  +DL NN IS +    F  +  L  L LS NR+ C+ 
Sbjct: 459 LYLEGNHLTAVPR-ELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIP 517

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F GL  L  L + GN  SS+  G F++L +L  + LGT  L CDC LRWL  W +  
Sbjct: 518 VHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVK-A 576

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELH 239
             +      C+ P  +  + L +    +  C+G ++++
Sbjct: 577 GYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDIN 614



 Score = 52.3 bits (123), Expect = 5e-05
 Identities = 37/112 (33%), Positives = 56/112 (49%), Gaps = 4/112 (3%)

Query: 77  NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 136
           +G  TL+L +N I  + N +F GLS +  L L +N I+T+ PGAF  L  L  ++L +N 
Sbjct: 307 SGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNP 366

Query: 137 IGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCD 188
             C     + G     R  +SGN     +P    E+P   + D+  +  TCD
Sbjct: 367 FNCNCHLAWLGKWLRKRRIVSGNP-RCQKPFFLKEIP---IQDVAIQDFTCD 414



 Score = 37.9 bits (86), Expect = 1.0
 Identities = 23/59 (38%), Positives = 31/59 (51%)

Query: 81  TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           TL+LS N++  +   +F GL  L  L L  N IS+V  G+F  L  L  L L  N + C
Sbjct: 505 TLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHC 563



>ref|NP_003053.1| (NM_003062) slit (Drosophila) homolog 3; slit2; slit (Drosophila)
           homolog 2 [Homo sapiens]
 dbj|BAA35186.1| (AB017169) Slit-3 protein [Homo sapiens]
          Length = 1523

 Score = 94.4 bits (231), Expect = 1e-17
 Identities = 52/151 (34%), Positives = 82/151 (53%), Gaps = 1/151 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNNKI  +R G+F G + +++L L  N + TV    F GL  LK L L +N IGC++++
Sbjct: 564 LSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSND 623

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           TF GL  +  L++  N  +++ PG F  L +L  ++L +    C+CHL WL  W + R +
Sbjct: 624 TFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRI 683

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
            +S +  C  P  L    +  +      C+G
Sbjct: 684 -VSGNPRCQKPFFLKEIPIQDVAIQDFTCDG 713



 Score = 85.0 bits (207), Expect = 7e-15
 Identities = 58/227 (25%), Positives = 91/227 (39%), Gaps = 25/227 (11%)

Query: 30  CPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSXXXXXXXXXXXXXXNGTVTLLLSNNKI 89
           C  S  S  C G   + +  G+P  A R  +                     L L +N++
Sbjct: 38  CTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQV 97

Query: 90  TGLRNGSFLGLSLLEKL------------------------DLRNNIISTVQPGAFLGLG 125
           + +  G+F  L  LE+L                        DL  N I  +   AF G+ 
Sbjct: 98  SVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGIT 157

Query: 126 ELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFL 185
           ++K L L NN I C+    F+ L  L  L ++ N  S +    F+ +P ++ + L +  L
Sbjct: 158 DVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217

Query: 186 TCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCC 232
            CDCHL WL  W + R   + + TLC  P  L    +  +Q+ +  C
Sbjct: 218 YCDCHLAWLSDWLRQRR-TVGQFTLCMAPVHLRGFNVADVQKKEYVC 263



 Score = 84.3 bits (205), Expect = 1e-14
 Identities = 47/152 (30%), Positives = 78/152 (50%), Gaps = 1/152 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           +S N+I+ +   +F GL  L  L L  N I+ +  G F GL  L+ L L+ N+I CL   
Sbjct: 338 ISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVN 397

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           TFQ L  L  L++  N   ++  G+F  L +++ + L      CDCHL+WL  + Q+  +
Sbjct: 398 TFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPI 457

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEGA 235
           + S    C+ P  L  + +  ++  +  C G+
Sbjct: 458 ETS-GARCSSPRRLANKRISQIKSKKFRCSGS 488



 Score = 76.5 bits (185), Expect = 3e-12
 Identities = 50/158 (31%), Positives = 75/158 (46%), Gaps = 2/158 (1%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L  N +T +       L  L  +DL NN IS +    F  +  L  L LS NR+ C+ 
Sbjct: 757 LYLEGNHLTAVPR-ELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIP 815

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F GL  L  L + GN  SS+  G F++L +L  + LGT  L CDC LRWL  W +  
Sbjct: 816 VHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVK-A 874

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELH 239
             +      C+ P  +  + L +    +  C+G ++++
Sbjct: 875 GYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDIN 912



 Score = 52.3 bits (123), Expect = 5e-05
 Identities = 37/112 (33%), Positives = 56/112 (49%), Gaps = 4/112 (3%)

Query: 77  NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 136
           +G  TL+L +N I  + N +F GLS +  L L +N I+T+ PGAF  L  L  ++L +N 
Sbjct: 605 SGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNP 664

Query: 137 IGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCD 188
             C     + G     R  +SGN     +P    E+P   + D+  +  TCD
Sbjct: 665 FNCNCHLAWLGKWLRKRRIVSGNP-RCQKPFFLKEIP---IQDVAIQDFTCD 712



 Score = 37.9 bits (86), Expect = 1.0
 Identities = 23/59 (38%), Positives = 31/59 (51%)

Query: 81  TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           TL+LS N++  +   +F GL  L  L L  N IS+V  G+F  L  L  L L  N + C
Sbjct: 803 TLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHC 861



>ref|NP_476727.1| (NM_057379) sli-P3 [Drosophila melanogaster]
 gb|AAF58097.1| (AE003809) sli gene product [alt 1] [Drosophila melanogaster]
          Length = 1504

 Score = 94.0 bits (230), Expect = 1e-17
 Identities = 52/156 (33%), Positives = 80/156 (50%), Gaps = 1/156 (0%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L+NN++  +        + L +LD+ NN+I+TV    F G   L+ L L NN+I CL 
Sbjct: 153 LRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLD 212

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+GL  L  L ++ N  +SL   +F  L  L+ + L      CDCHL WL  + ++ 
Sbjct: 213 EHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRS- 271

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALE 237
           + +L+ +T C  PS L  Q +  L + +  C G  E
Sbjct: 272 ATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTE 307



 Score = 90.1 bits (220), Expect = 2e-16
 Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 1/149 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN I+ + + +  GL  L  L L  N I  +  G F GLG L+ L L+ N I C+  +
Sbjct: 377 LSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEISCIRKD 436

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            F+ L  L  L++  N   SL  G FD + ++K V L      CDC+LRWL  +     +
Sbjct: 437 AFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHLAKNPFICDCNLRWLADYLHKNPI 496

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCC 232
           + S    C  P  +H + + SL+E +  C
Sbjct: 497 ETS-GARCESPKRMHRRRIESLREEKFKC 524



 Score = 85.8 bits (209), Expect = 4e-15
 Identities = 47/155 (30%), Positives = 81/155 (51%), Gaps = 2/155 (1%)

Query: 79  TVTLLLSNNKITGLRNGSFLG-LSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRI 137
           T  LLL++N++  + +    G L  L KL+L+ N ++ ++P AF G   ++ L L  N+I
Sbjct: 572 TTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKI 631

Query: 138 GCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPW 197
             ++++ F GL +L  LN+  N  S + PG F+ L +L  ++L +    C+CHL W   W
Sbjct: 632 KEISNKMFLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEW 691

Query: 198 AQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCC 232
            + +SL       C  PS +    +  L  ++  C
Sbjct: 692 LRKKSLN-GGAARCGAPSKVRDVQIKDLPHSEFKC 725



 Score = 76.1 bits (184), Expect = 3e-12
 Identities = 50/158 (31%), Positives = 74/158 (46%), Gaps = 5/158 (3%)

Query: 79  TVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIG 138
           T  L L +N+I  +       L  L +LDL NN I+ +    F  L +L  L +S N++ 
Sbjct: 768 TSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQ 827

Query: 139 CLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWA 198
           CL      GL  L  L++ GN  S L  G F++L +L  + LG+  L CDC L+W   W 
Sbjct: 828 CLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWI 887

Query: 199 QNRSLQLSEHTL--CAYPSALHAQALGSLQEAQLCCEG 234
           +   L   E  +  CA P  +  + + S   +   C G
Sbjct: 888 K---LDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRG 922



>gb|AAD26567.1|AF126540_1 (AF126540) slit protein [Drosophila melanogaster]
          Length = 1504

 Score = 94.0 bits (230), Expect = 1e-17
 Identities = 52/156 (33%), Positives = 80/156 (50%), Gaps = 1/156 (0%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L+NN++  +        + L +LD+ NN+I+TV    F G   L+ L L NN+I CL 
Sbjct: 153 LRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLD 212

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+GL  L  L ++ N  +SL   +F  L  L+ + L      CDCHL WL  + ++ 
Sbjct: 213 EHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRS- 271

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALE 237
           + +L+ +T C  PS L  Q +  L + +  C G  E
Sbjct: 272 ATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTE 307



 Score = 90.1 bits (220), Expect = 2e-16
 Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 1/149 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN I+ + + +  GL  L  L L  N I  +  G F GLG L+ L L+ N I C+  +
Sbjct: 377 LSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEISCIRKD 436

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            F+ L  L  L++  N   SL  G FD + ++K V L      CDC+LRWL  +     +
Sbjct: 437 AFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHLAKNPFICDCNLRWLADYLHKNPI 496

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCC 232
           + S    C  P  +H + + SL+E +  C
Sbjct: 497 ETS-GARCESPKRMHRRRIESLREEKFKC 524



 Score = 85.8 bits (209), Expect = 4e-15
 Identities = 47/155 (30%), Positives = 81/155 (51%), Gaps = 2/155 (1%)

Query: 79  TVTLLLSNNKITGLRNGSFLG-LSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRI 137
           T  LLL++N++  + +    G L  L KL+L+ N ++ ++P AF G   ++ L L  N+I
Sbjct: 572 TTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKI 631

Query: 138 GCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPW 197
             ++++ F GL +L  LN+  N  S + PG F+ L +L  ++L +    C+CHL W   W
Sbjct: 632 KEISNKMFLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEW 691

Query: 198 AQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCC 232
            + +SL       C  PS +    +  L  ++  C
Sbjct: 692 LRKKSLN-GGAARCGAPSKVRDVQIKDLPHSEFKC 725



 Score = 76.1 bits (184), Expect = 3e-12
 Identities = 50/158 (31%), Positives = 74/158 (46%), Gaps = 5/158 (3%)

Query: 79  TVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIG 138
           T  L L +N+I  +       L  L +LDL NN I+ +    F  L +L  L +S N++ 
Sbjct: 768 TSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQ 827

Query: 139 CLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWA 198
           CL      GL  L  L++ GN  S L  G F++L +L  + LG+  L CDC L+W   W 
Sbjct: 828 CLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWI 887

Query: 199 QNRSLQLSEHTL--CAYPSALHAQALGSLQEAQLCCEG 234
           +   L   E  +  CA P  +  + + S   +   C G
Sbjct: 888 K---LDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRG 922



>ref|NP_075242.1| (NM_022953) Slit1 [Rattus norvegicus]
 pir||T42218 slit-1 protein homolog - rat
 dbj|BAA32460.1| (AB011530) MEGF4 [Rattus norvegicus]
          Length = 1531

 Score = 93.6 bits (229), Expect = 2e-17
 Identities = 51/154 (33%), Positives = 82/154 (53%), Gaps = 1/154 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNNK++ + +G+F G + + +L L  N + +V+ G F GL  L+ L L NNRI C+ ++
Sbjct: 572 LSNNKVSEIEDGTFEGATSVSELHLTANQLESVRSGMFRGLDGLRTLMLRNNRISCIHND 631

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           +F GL  +  L++  N  +++ PG FD L AL  ++L      C+C L WL  W + R +
Sbjct: 632 SFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTLNLLANPFNCNCQLAWLGDWLRKRKI 691

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEGALE 237
            ++ +  C  P  L    L  +      CE   E
Sbjct: 692 -VTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQE 724



 Score = 85.4 bits (208), Expect = 5e-15
 Identities = 47/153 (30%), Positives = 75/153 (48%), Gaps = 1/153 (0%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L+ N++  L    F     L +LDL  N +  V   AF G  +LK L L  N+I C+ 
Sbjct: 114 LRLNRNQLQVLPELLFQNNQALSRLDLSENSLQAVPRKAFRGATDLKNLQLDKNQISCIE 173

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+ L  L  L ++ N  +++    F+ +P L+   L +  L CDCHL WL  W + R
Sbjct: 174 EGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQR 233

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
              +   T C+ P++L    +  +Q+++  C G
Sbjct: 234 P-TIGLFTQCSGPASLRGLNVAEVQKSEFSCSG 265



 Score = 84.3 bits (205), Expect = 1e-14
 Identities = 51/153 (33%), Positives = 77/153 (49%), Gaps = 2/153 (1%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L  N+ T L  G       L+ +DL NN IS++   +F  + +L  L LS N + C+ 
Sbjct: 766 LYLDGNQFT-LVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIP 824

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              FQGL  L  L++ GN  S+LQ G+F ++ +L  + +G   L CDCHLRWL  W +  
Sbjct: 825 PLAFQGLRSLRLLSLHGNDVSTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSWVKT- 883

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
             +      CA P  +  + L +    +  C+G
Sbjct: 884 GYKEPGIARCAGPPEMEGKLLLTTPAKKFECQG 916



 Score = 81.1 bits (197), Expect = 1e-13
 Identities = 48/149 (32%), Positives = 75/149 (50%), Gaps = 1/149 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN+I  +   +F GL  L  L L  N I+ +  G F GL  L+ L L+ N+I C+  +
Sbjct: 340 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 399

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            FQ L  L  L++  N   SL  G F  L A++ + L      CDC+L+WL  + +   +
Sbjct: 400 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPI 459

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCC 232
           + +    CA P  L  + +G ++  +  C
Sbjct: 460 E-TTGARCASPRRLANKRIGQIKSKKFRC 487



 Score = 49.6 bits (116), Expect = 3e-04
 Identities = 27/63 (42%), Positives = 37/63 (57%)

Query: 77  NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 136
           +G  TL+L NN+I+ + N SF GL  +  L L +N I+T+ PGAF  L  L  L+L  N 
Sbjct: 613 DGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTLNLLANP 672

Query: 137 IGC 139
             C
Sbjct: 673 FNC 675



>gb|AAL14445.1|AF387318_1 (AF387318) slit-3 [Gallus gallus]
          Length = 1095

 Score = 93.2 bits (228), Expect = 2e-17
 Identities = 52/151 (34%), Positives = 79/151 (51%), Gaps = 1/151 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNNKI  +R G+F G S +++L L  N + +V    F GL  LK L L +N I C+ ++
Sbjct: 135 LSNNKIKEIREGTFDGASGVQELILTENQLESVHGRMFRGLTGLKTLMLRSNSISCINND 194

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           TF GL  +  L++  N  S++ PG F  L +L  ++L      C+CHL WL  W + + +
Sbjct: 195 TFAGLSSVRLLSLYDNHISTITPGAFSTLVSLSTINLLANSFNCNCHLAWLGKWLRKKRI 254

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
            +S +  C  P  L    +  +      CEG
Sbjct: 255 -VSGNPRCLKPFFLKDIPIQDVDAQDFTCEG 284



 Score = 77.6 bits (188), Expect = 1e-12
 Identities = 47/120 (39%), Positives = 65/120 (54%), Gaps = 5/120 (4%)

Query: 82  LLLSNNKITGLRNG--SFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           L L  N +T +  G  +F  L+L+   DL NN IS +    F  + +L  L LS NR+ C
Sbjct: 328 LYLEGNHLTAVPKGLSAFRHLTLI---DLSNNSISVLANYTFSNMTQLSTLILSYNRLRC 384

Query: 140 LTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQ 199
           +    F GL  L  L + GN  SS+  G F++L +L  + LGT  L CDC+LRWL  W +
Sbjct: 385 IPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLVSLSHLALGTNPLHCDCNLRWLSEWVK 444



 Score = 37.5 bits (85), Expect = 1.4
 Identities = 23/59 (38%), Positives = 31/59 (51%)

Query: 81  TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           TL+LS N++  +   +F GL  L  L L  N IS+V  G+F  L  L  L L  N + C
Sbjct: 374 TLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLVSLSHLALGTNPLHC 432



 Score = 35.2 bits (79), Expect = 6.9
 Identities = 14/49 (28%), Positives = 26/49 (52%), Gaps = 1/49 (2%)

Query: 187 CDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGA 235
           CDCHL+WL  + Q+  ++ S    C+ P  L  + +  ++  +  C G+
Sbjct: 12  CDCHLKWLADYLQDNPIETS-GARCSNPRRLANKRISQIKSKKFRCSGS 59



>dbj|BAB31253.1| (AK018522) putative [Mus musculus]
          Length = 740

 Score = 93.2 bits (228), Expect = 2e-17
 Identities = 60/222 (27%), Positives = 102/222 (45%), Gaps = 4/222 (1%)

Query: 119 GAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVV 178
           GAF GL  L++L L  NRI  +T + F GL  L  L++SGN   SLQ   F ++  L+ +
Sbjct: 3   GAFSGLDRLRQLILQGNRIRSITKKAFAGLDTLEHLDLSGNAIMSLQSNAFSQMKKLQQL 62

Query: 179 DLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALEL 238
            L T  L CDC LRWL  W    + Q   +  CA+P  L  +++ ++      C+   + 
Sbjct: 63  HLNTSSLLCDCQLRWLPQWVAENNFQSFVNASCAHPQLLKGRSIFTVSPDGFVCDDFPK- 121

Query: 239 HTHHLIPSLRQVVFQGDRLPFQCS-ASYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIH 297
                +    Q   +G  + F CS AS   +     W  +   ++  E        +   
Sbjct: 122 -PQITVQPETQSAIKGSDVSFTCSAASSSDSPMTFAWKKDNEALQDAEMENYAHLRAQGG 180

Query: 298 DCTFITSELTLSHIGVWASGEWECTVSMAQGNA-SKKVEIVV 338
           +    T+ L L ++   + G+++C +S   G++ S K ++ +
Sbjct: 181 ELMEYTTILRLRNVEFTSEGKYQCVISNHFGSSYSVKAKLTI 222



>gb|AAG36773.1| (AF210321) Slit2 [Danio rerio]
          Length = 1512

 Score = 92.4 bits (226), Expect = 4e-17
 Identities = 53/151 (35%), Positives = 79/151 (52%), Gaps = 1/151 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN+IT L + SF GL  L  L L  N I+ +  G F GL  L+ L L+ N+I CL  +
Sbjct: 322 LSNNQITELASDSFQGLRSLNSLVLYGNKITELPKGLFDGLFSLQLLLLNANKINCLRVD 381

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           +FQ L  L  L++  N   ++  G F  L A++ + L      CDCHL+WL  + Q+  +
Sbjct: 382 SFQDLQNLNLLSLYDNKLQTIAKGTFSSLRAIQTLHLAQNPFMCDCHLKWLADYLQDNPI 441

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
           + S    C  P  L  + +G ++  +  C G
Sbjct: 442 ETS-GARCTSPRRLANKRIGQIKSKKFRCSG 471



 Score = 91.3 bits (223), Expect = 9e-17
 Identities = 50/150 (33%), Positives = 79/150 (52%), Gaps = 1/150 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNNKIT +  G+F G S + +L L +N +  V      GLG L+ L L +NRI C+ + 
Sbjct: 548 LSNNKITDIEEGTFEGASGVNELILTSNRLEGVHYSMLKGLGGLRTLMLRSNRISCVNNG 607

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           +F GL  +  L++  N+ +S+ PG FD L +L  ++L      C+CHL WL  W + + +
Sbjct: 608 SFTGLSSVRLLSLYDNLITSMSPGAFDTLHSLSTLNLLANPFNCNCHLAWLGEWLRKKRI 667

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCE 233
            ++ +  C  P  L    +  +      CE
Sbjct: 668 -VTGNPRCQSPYFLKEIPIQDVAVQDFACE 696



 Score = 86.6 bits (211), Expect = 2e-15
 Identities = 50/153 (32%), Positives = 75/153 (48%), Gaps = 1/153 (0%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L+ N +  L    FLG + L +LDL  N I  +   AF G  E+K L L  N+I C+ 
Sbjct: 101 LRLNRNNLQVLPELLFLGTTKLFRLDLSENQIQGIPRKAFRGSTEIKNLQLDYNQISCIE 160

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+ L  L  L ++ N  S L    F+ +P L+   L +  L CDC++ WL  W + R
Sbjct: 161 DGAFRALGDLEVLTLNNNNISRLSVASFNHMPKLRTFRLHSNNLLCDCNVAWLSDWLRQR 220

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
             +L  +T C  P +L    +  +Q+ +  C G
Sbjct: 221 P-RLGLYTQCMAPPSLRGHNIAEVQKKEFMCTG 252



 Score = 77.6 bits (188), Expect = 1e-12
 Identities = 43/136 (31%), Positives = 70/136 (50%), Gaps = 1/136 (0%)

Query: 103 LEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFS 162
           L  +DL NN IST+   +F  + EL  L LS NR+ C+ ++ F GL  L  L++ GN  +
Sbjct: 762 LTLIDLSNNQISTLSNHSFSNMSELLTLILSYNRLRCIPAKAFDGLKSLRLLSLHGNDIA 821

Query: 163 SLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQAL 222
            +  G F +L +L  + LG   L CDCH++WL  W ++   +      C  P  +  + L
Sbjct: 822 VIPDGAFKDLSSLSHLALGANPLYCDCHMQWLSDWVKS-GYKEPGIARCTGPGDMTDKLL 880

Query: 223 GSLQEAQLCCEGALEL 238
            +    +  C G +++
Sbjct: 881 LTTPSKKFTCTGPVDV 896



 Score = 51.9 bits (122), Expect = 6e-05
 Identities = 27/62 (43%), Positives = 39/62 (62%)

Query: 78  GTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRI 137
           G  TL+L +N+I+ + NGSF GLS +  L L +N+I+++ PGAF  L  L  L+L  N  
Sbjct: 590 GLRTLMLRSNRISCVNNGSFTGLSSVRLLSLYDNLITSMSPGAFDTLHSLSTLNLLANPF 649

Query: 138 GC 139
            C
Sbjct: 650 NC 651



 Score = 38.3 bits (87), Expect = 0.79
 Identities = 22/60 (36%), Positives = 31/60 (51%)

Query: 80  VTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           +TL+LS N++  +   +F GL  L  L L  N I+ +  GAF  L  L  L L  N + C
Sbjct: 787 LTLILSYNRLRCIPAKAFDGLKSLRLLSLHGNDIAVIPDGAFKDLSSLSHLALGANPLYC 846



>gb|AAD25540.1|AF133730_1 (AF133730) Slit1 [Rattus norvegicus]
          Length = 1530

 Score = 91.7 bits (224), Expect = 7e-17
 Identities = 51/154 (33%), Positives = 81/154 (52%), Gaps = 1/154 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNNK++ + +G+F G + + +L L  N + +V+ G F GL  L  L L NNRI C+ ++
Sbjct: 572 LSNNKVSEIEDGTFEGATSVSELHLTANQLESVRSGMFRGLDGLWSLMLRNNRISCIHND 631

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           +F GL  +  L++  N  +++ PG FD L AL  ++L      C+C L WL  W + R +
Sbjct: 632 SFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTLNLLANPFNCNCQLAWLGDWLRKRKI 691

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEGALE 237
            ++ +  C  P  L    L  +      CE   E
Sbjct: 692 -VTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQE 724



 Score = 84.7 bits (206), Expect = 9e-15
 Identities = 46/151 (30%), Positives = 74/151 (48%), Gaps = 1/151 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           L+ N++  L    F     L +LDL  N +  V   AF G  +LK L L  N+I C+   
Sbjct: 116 LNRNQLQMLPELLFQNNQALSRLDLSENSLQAVPRKAFRGATDLKNLQLDKNQISCIEEG 175

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            F+ L  L  L ++ N  +++    F+ +P L+   L +  L CDCHL WL  W + R  
Sbjct: 176 AFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRP- 234

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
            +   T C+ P++L    +  +Q+++  C G
Sbjct: 235 TIGLFTQCSGPASLRGLNVAEVQKSEFSCSG 265



 Score = 84.3 bits (205), Expect = 1e-14
 Identities = 51/153 (33%), Positives = 77/153 (49%), Gaps = 2/153 (1%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L  N+ T L  G       L+ +DL NN IS++   +F  + +L  L LS N + C+ 
Sbjct: 765 LYLDGNQFT-LVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIP 823

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              FQGL  L  L++ GN  S+LQ G+F ++ +L  + +G   L CDCHLRWL  W +  
Sbjct: 824 PLAFQGLRSLRLLSLHGNDVSTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSWVKT- 882

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
             +      CA P  +  + L +    +  C+G
Sbjct: 883 GYKEPGIARCAGPPEMEGKLLLTTPAKKFECQG 915



 Score = 81.1 bits (197), Expect = 1e-13
 Identities = 48/149 (32%), Positives = 75/149 (50%), Gaps = 1/149 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN+I  +   +F GL  L  L L  N I+ +  G F GL  L+ L L+ N+I C+  +
Sbjct: 340 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 399

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            FQ L  L  L++  N   SL  G F  L A++ + L      CDC+L+WL  + +   +
Sbjct: 400 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPI 459

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCC 232
           + +    CA P  L  + +G ++  +  C
Sbjct: 460 E-TTGARCASPRRLANKRIGQIKSKKFRC 487



 Score = 48.0 bits (112), Expect = 0.001
 Identities = 26/63 (41%), Positives = 37/63 (58%)

Query: 77  NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 136
           +G  +L+L NN+I+ + N SF GL  +  L L +N I+T+ PGAF  L  L  L+L  N 
Sbjct: 613 DGLWSLMLRNNRISCIHNDSFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTLNLLANP 672

Query: 137 IGC 139
             C
Sbjct: 673 FNC 675



>ref|XP_050940.1| (XM_050940) slit (Drosophila) homolog 1 [Homo sapiens]
          Length = 1331

 Score = 91.3 bits (223), Expect = 9e-17
 Identities = 49/154 (31%), Positives = 82/154 (52%), Gaps = 1/154 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNNK++ + +G+F G + + +L L  N + +++ G F GL  L+ L L NNRI C+ ++
Sbjct: 369 LSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 428

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           +F GL  +  L++  N  +++ PG FD L +L  ++L      C+C L WL  W + R +
Sbjct: 429 SFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKI 488

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEGALE 237
            ++ +  C  P  L    L  +      CE   E
Sbjct: 489 -VTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQE 521



 Score = 84.7 bits (206), Expect = 9e-15
 Identities = 51/153 (33%), Positives = 77/153 (49%), Gaps = 2/153 (1%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L  N+ T L  G       L+ +DL NN IS++   +F  + +L  L LS N + C+ 
Sbjct: 563 LYLDGNQFT-LVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIP 621

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              FQGL  L  L++ GN  S+LQ G+F ++ +L  + +G   L CDCHLRWL  W +  
Sbjct: 622 PLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSWVKT- 680

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
             +      CA P  +  + L +    +  C+G
Sbjct: 681 GYKEPGIARCAGPQDMEGKLLLTTPAKKFECQG 713



 Score = 82.3 bits (200), Expect = 4e-14
 Identities = 49/149 (32%), Positives = 75/149 (49%), Gaps = 1/149 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN+I  +   +F GL  L  L L  N I+ +  G F GL  L+ L L+ N+I C+  +
Sbjct: 137 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 196

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            FQ L  L  L++  N   SL  G F  L A++ + L      CDC+L+WL  + +   +
Sbjct: 197 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPI 256

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCC 232
           + S    CA P  L  + +G ++  +  C
Sbjct: 257 ETS-GARCASPRRLANKRIGQIKSKKFRC 284



 Score = 50.4 bits (118), Expect = 2e-04
 Identities = 28/63 (44%), Positives = 37/63 (58%)

Query: 77  NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 136
           +G  TL+L NN+I+ + N SF GL  +  L L +N I+TV PGAF  L  L  L+L  N 
Sbjct: 410 DGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 469

Query: 137 IGC 139
             C
Sbjct: 470 FNC 472



 Score = 45.7 bits (106), Expect = 0.005
 Identities = 20/63 (31%), Positives = 33/63 (51%), Gaps = 1/63 (1%)

Query: 172 LPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLC 231
           +P L+   L +  L CDCHL WL  W + R   +   T C+ P++L    +  +Q+++  
Sbjct: 1   MPKLRTFRLHSNHLFCDCHLAWLSQWLRQRP-TIGLFTQCSGPASLRGLNVAEVQKSEFS 59

Query: 232 CEG 234
           C G
Sbjct: 60  CSG 62



>ref|NP_003052.1| (NM_003061) slit (Drosophila) homolog 1; slit1 [Homo sapiens]
 dbj|BAA35184.1| (AB017167) Slit-1 protein [Homo sapiens]
          Length = 1534

 Score = 91.3 bits (223), Expect = 9e-17
 Identities = 49/154 (31%), Positives = 82/154 (52%), Gaps = 1/154 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNNK++ + +G+F G + + +L L  N + +++ G F GL  L+ L L NNRI C+ ++
Sbjct: 572 LSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 631

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           +F GL  +  L++  N  +++ PG FD L +L  ++L      C+C L WL  W + R +
Sbjct: 632 SFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKI 691

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEGALE 237
            ++ +  C  P  L    L  +      CE   E
Sbjct: 692 -VTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQE 724



 Score = 85.0 bits (207), Expect = 7e-15
 Identities = 47/153 (30%), Positives = 75/153 (48%), Gaps = 1/153 (0%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L+ N++  L    F     L +LDL  N I  +   AF G  +LK L L  N+I C+ 
Sbjct: 114 LRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIE 173

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+ L  L  L ++ N  +++    F+ +P L+   L +  L CDCHL WL  W + R
Sbjct: 174 EGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQR 233

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
              +   T C+ P++L    +  +Q+++  C G
Sbjct: 234 P-TIGLFTQCSGPASLRGLNVAEVQKSEFSCSG 265



 Score = 84.7 bits (206), Expect = 9e-15
 Identities = 51/153 (33%), Positives = 77/153 (49%), Gaps = 2/153 (1%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L  N+ T L  G       L+ +DL NN IS++   +F  + +L  L LS N + C+ 
Sbjct: 766 LYLDGNQFT-LVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIP 824

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              FQGL  L  L++ GN  S+LQ G+F ++ +L  + +G   L CDCHLRWL  W +  
Sbjct: 825 PLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSWVKT- 883

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
             +      CA P  +  + L +    +  C+G
Sbjct: 884 GYKEPGIARCAGPQDMEGKLLLTTPAKKFECQG 916



 Score = 82.3 bits (200), Expect = 4e-14
 Identities = 49/149 (32%), Positives = 75/149 (49%), Gaps = 1/149 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN+I  +   +F GL  L  L L  N I+ +  G F GL  L+ L L+ N+I C+  +
Sbjct: 340 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 399

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            FQ L  L  L++  N   SL  G F  L A++ + L      CDC+L+WL  + +   +
Sbjct: 400 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPI 459

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCC 232
           + S    CA P  L  + +G ++  +  C
Sbjct: 460 ETS-GARCASPRRLANKRIGQIKSKKFRC 487



 Score = 50.4 bits (118), Expect = 2e-04
 Identities = 28/63 (44%), Positives = 37/63 (58%)

Query: 77  NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 136
           +G  TL+L NN+I+ + N SF GL  +  L L +N I+TV PGAF  L  L  L+L  N 
Sbjct: 613 DGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 672

Query: 137 IGC 139
             C
Sbjct: 673 FNC 675



>ref|XP_003557.4| (XM_003557) hypothetical protein XP_003557 [Homo sapiens]
          Length = 1525

 Score = 90.9 bits (222), Expect = 1e-16
 Identities = 53/165 (32%), Positives = 79/165 (47%), Gaps = 1/165 (0%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L+ N +       FLG + L +LDL  N I  +   AF G  ++K L L  N+I C+ 
Sbjct: 108 LRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 167

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+ L  L  L ++ N  + L    F+ +P L+   L +  L CDCHL WL  W + R
Sbjct: 168 DGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQR 227

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPS 246
             ++  +T C  PS L    +  +Q+ +  C G  E H   + PS
Sbjct: 228 P-RVGLYTQCMGPSHLRGHNVAEVQKREFVCSGKGEGHQSFMAPS 271



 Score = 83.5 bits (203), Expect = 2e-14
 Identities = 43/119 (36%), Positives = 69/119 (57%)

Query: 85  SNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSET 144
           SNNKIT +  G+F G S + ++ L +N +  VQ   F GL  LK L L +NRI C+ +++
Sbjct: 562 SNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDS 621

Query: 145 FQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           F GL  +  L++  N  +++ PG FD L +L  ++L      C+C+L WL  W + + +
Sbjct: 622 FIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRI 680



 Score = 83.1 bits (202), Expect = 3e-14
 Identities = 49/151 (32%), Positives = 74/151 (48%), Gaps = 1/151 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN+I+ L   +F GL  L  L L  N I+ +    F GL  L+ L L+ N+I CL  +
Sbjct: 335 LSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVD 394

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            FQ L  L  L++  N   ++  G F  L A++ + L      CDCHL+WL  +     +
Sbjct: 395 AFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPI 454

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
           + S    C  P  L  + +G ++  +  C G
Sbjct: 455 ETS-GARCTSPRRLANKRIGQIKSKKFRCSG 484



 Score = 79.6 bits (193), Expect = 3e-13
 Identities = 44/137 (32%), Positives = 73/137 (53%), Gaps = 1/137 (0%)

Query: 103 LEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFS 162
           L  +DL NN IST+   +F  + +L  L LS NR+ C+   TF GL  L  L++ GN  S
Sbjct: 775 LTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDIS 834

Query: 163 SLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQAL 222
            +  G F++L AL  + +G   L CDC+++WL  W ++   +      CA P  +  + L
Sbjct: 835 VVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKE-PGIARCAGPGEMADKLL 893

Query: 223 GSLQEAQLCCEGALELH 239
            +    +  C+G ++++
Sbjct: 894 LTTPSKKFTCQGPVDVN 910



 Score = 53.1 bits (125), Expect = 3e-05
 Identities = 38/108 (35%), Positives = 56/108 (51%), Gaps = 4/108 (3%)

Query: 81  TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 140
           TL+L +N+IT + N SF+GLS +  L L +N I+TV PGAF  L  L  L+L  N   C 
Sbjct: 606 TLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCN 665

Query: 141 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCD 188
               + G     +  ++GN     +P    E+P   + D+  +  TCD
Sbjct: 666 CYLAWLGEWLRKKRIVTGNP-RCQKPYFLKEIP---IQDVAIQDFTCD 709



 Score = 38.3 bits (87), Expect = 0.79
 Identities = 23/60 (38%), Positives = 31/60 (51%)

Query: 80  VTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           +TL+LS N++  +   +F GL  L  L L  N IS V  GAF  L  L  L +  N + C
Sbjct: 800 LTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYC 859



>gb|AAG36772.1|AF210320_1 (AF210320) Slit3 [Danio rerio]
          Length = 1515

 Score = 89.3 bits (218), Expect = 3e-16
 Identities = 63/240 (26%), Positives = 95/240 (39%), Gaps = 25/240 (10%)

Query: 30  CPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSXXXXXXXXXXXXXXNGTVTLLLSNNKI 89
           C  S     C G+  K +  G+P  A R  +                     L L NN+I
Sbjct: 28  CSCSGSHVDCQGQAFKTVPRGIPRNAERLDLDRNNITRITKVDFSGLKNLRVLHLENNQI 87

Query: 90  TGLRNGSFLGLSLLEK------------------------LDLRNNIISTVQPGAFLGLG 125
           + +  G+F GL  LE+                        LDL  N I  V   AF G+ 
Sbjct: 88  SVIERGAFEGLKQLERIRLNRNRLQVLPELLFQSTTKLSRLDLSENQIQAVPRKAFRGIT 147

Query: 126 ELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFL 185
            +K L L +N I C+    F+ L  L  L ++ N  + +    F+ +P L+ + L +  L
Sbjct: 148 TVKNLQLDSNHISCIEDGAFRALRDLEILTLNNNNITLIPLSSFNHMPKLRTLRLHSNNL 207

Query: 186 TCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIP 245
            CDCHL WL  W + R   L+  T C  P+ +    +  +Q+ +  C G +E       P
Sbjct: 208 HCDCHLSWLSDWLRQRR-GLAPFTQCMAPAHMRGLNVPDVQKREFVCTGPVETEPRSCAP 266



 Score = 89.3 bits (218), Expect = 3e-16
 Identities = 52/154 (33%), Positives = 83/154 (53%), Gaps = 1/154 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNNK+  +R G+F G   + +L L  N + +V    F GL  LK L L +N+I C+ + 
Sbjct: 555 LSNNKLRDIREGAFDGAGGVLELLLTGNKLQSVSGRMFKGLIGLKTLMLRSNQISCVDNA 614

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           TF GL  +  L++  N  S++ PG F+ L +L  ++L +    CDCHL WL  W + ++ 
Sbjct: 615 TFTGLSSVRLLSLHDNRISTIAPGAFNTLHSLSTINLLSNPYVCDCHLAWLGLWLK-KTR 673

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEGALE 237
            +S +  C  P+ L    +  +   +  C+GA E
Sbjct: 674 VVSGNPRCQKPAFLKEIPIQDVAMPEFSCDGAEE 707



 Score = 83.5 bits (203), Expect = 2e-14
 Identities = 49/152 (32%), Positives = 78/152 (51%), Gaps = 1/152 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LS N+I+ +   +F GL  L  L L  N I+ +  G F GL  L+ L L+ N+I CL   
Sbjct: 329 LSKNQISEIAEDAFSGLRSLTSLVLYGNKIAEIPKGLFDGLVSLQLLLLNANKINCLRVN 388

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           TF+ L  L  L++  N   ++  G+F  L A+K + L      CDCHL+WL  +  +  +
Sbjct: 389 TFKDLQNLNLLSLYDNKLQTISKGLFAPLRAIKTLHLAQNPFMCDCHLKWLADYLFDNPI 448

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEGA 235
           + S    C++P  L  + +  ++  +  C GA
Sbjct: 449 ETS-GARCSHPRRLANKRISQVKGKKFRCTGA 479



 Score = 76.5 bits (185), Expect = 3e-12
 Identities = 46/121 (38%), Positives = 60/121 (49%), Gaps = 1/121 (0%)

Query: 79  TVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIG 138
           T  L L  N +T +       L  L  LDL NN IS + P  F  + +L  L LS N+I 
Sbjct: 746 TTELYLEGNLLTSVPK-ELPNLKQLTLLDLSNNSISHLAPLTFSNMTQLATLILSYNQIR 804

Query: 139 CLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWA 198
           C+    F GL  L  L + GN  S++  G F+ L +L  + LG   L CDC LRWL  W 
Sbjct: 805 CVPVHAFDGLRSLRLLTLHGNDLSTVPEGAFNHLTSLSHLALGANPLYCDCELRWLSQWV 864

Query: 199 Q 199
           +
Sbjct: 865 K 865



>gb|AAL14447.1| (AF387320) slit-2 [Gallus gallus]
          Length = 783

 Score = 88.9 bits (217), Expect = 5e-16
 Identities = 45/120 (37%), Positives = 71/120 (58%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNNKIT +  G+F G S + +L L +N + TV+   F GL  LK L L +NR+ C+ ++
Sbjct: 23  LSNNKITDIEEGAFDGASGVNELLLTSNRLETVRDKMFKGLESLKTLMLRSNRVSCVGND 82

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           +F GL  +  L++  N  +++ PG FD L +L  ++L      C+CHL WL  W + + +
Sbjct: 83  SFTGLSSVRLLSLYDNQITTVAPGSFDTLHSLSTLNLLANPFNCNCHLAWLGDWLRKKRI 142



 Score = 80.4 bits (195), Expect = 2e-13
 Identities = 44/137 (32%), Positives = 74/137 (53%), Gaps = 1/137 (0%)

Query: 103 LEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFS 162
           L  +DL NN IST+   +F  + +L  L LS NR+ C+ + TF GL  L  L++ GN  S
Sbjct: 237 LTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPARTFDGLKSLRLLSLHGNDIS 296

Query: 163 SLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQAL 222
            +  G F++L AL  + +G   L CDC+++WL  W ++   +      CA P  +  + L
Sbjct: 297 VVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKE-PGIARCAGPGEMADKLL 355

Query: 223 GSLQEAQLCCEGALELH 239
            +    +  C+G ++++
Sbjct: 356 LTTPSKKFTCQGPVDVN 372



 Score = 38.3 bits (87), Expect = 0.79
 Identities = 23/60 (38%), Positives = 31/60 (51%)

Query: 80  VTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           +TL+LS N++  +   +F GL  L  L L  N IS V  GAF  L  L  L +  N + C
Sbjct: 262 LTLILSYNRLRCIPARTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYC 321



>ref|NP_072154.1| (NM_022632) slit (Drosophila) homolog 2 [Rattus norvegicus]
 gb|AAD38940.2| (AF141386) SLIT-2 [Rattus norvegicus]
          Length = 796

 Score = 88.9 bits (217), Expect = 5e-16
 Identities = 52/165 (31%), Positives = 78/165 (46%), Gaps = 1/165 (0%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L+ N +       FLG + L +LDL  N I  +   AF G  ++K L L  N+I C+ 
Sbjct: 108 LRLNRNNLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 167

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+ L  L  L ++ N  + L    F+ +P L+   L +  L CDCHL WL  W + R
Sbjct: 168 DGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQR 227

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPS 246
             ++  +T C  PS L    +  +Q+ +  C    E H   + PS
Sbjct: 228 P-RVGLYTQCMGPSHLRGHNVAEVQKREFVCSDEEEGHQSFMAPS 271



 Score = 85.8 bits (209), Expect = 4e-15
 Identities = 44/120 (36%), Positives = 69/120 (56%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNNKIT +  G+F G S + ++ L +N +  VQ   F GL  LK L L +NRI C+ ++
Sbjct: 561 LSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGND 620

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           +F GL  +  L++  N  +++ PG F  L +L  ++L      C+CHL WL  W + + +
Sbjct: 621 SFTGLGSVRLLSLYDNQITTVAPGAFGTLHSLSTLNLLANPFNCNCHLAWLGEWLRRKRI 680



 Score = 82.7 bits (201), Expect = 3e-14
 Identities = 49/151 (32%), Positives = 74/151 (48%), Gaps = 1/151 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN+I+ L   +F GL  L  L L  N I+ +    F GL  L+ L L+ N+I CL  +
Sbjct: 335 LSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVD 394

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            FQ L  L  L++  N   ++  G F  L A++ + L      CDCHL+WL  +     +
Sbjct: 395 AFQDLHNLNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWLADYLHTNPI 454

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
           + S    C  P  L  + +G ++  +  C G
Sbjct: 455 ETS-GARCTSPRRLANKRIGQIKSKKFRCSG 484



>gb|AAD25539.1|AF133270_1 (AF133270) SLIT2 [Homo sapiens]
          Length = 1525

 Score = 88.5 bits (216), Expect = 6e-16
 Identities = 52/165 (31%), Positives = 78/165 (46%), Gaps = 1/165 (0%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L+ N +       FLG + L +LDL  N I  +   AF G  ++K L L  N+I C+ 
Sbjct: 108 LRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 167

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+ L  L  L ++ N  + L    F+ +P L+   L +  L CDCHL WL  W + R
Sbjct: 168 DGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRKR 227

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPS 246
             ++  +T C  PS L    +  +Q+ +  C    E H   + PS
Sbjct: 228 P-RVGLYTQCMGPSHLRGHNVAEVQKREFVCSDEEEGHQSFMAPS 271



 Score = 83.5 bits (203), Expect = 2e-14
 Identities = 43/119 (36%), Positives = 69/119 (57%)

Query: 85  SNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSET 144
           SNNKIT +  G+F G S + ++ L +N +  VQ   F GL  LK L L +NRI C+ +++
Sbjct: 562 SNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDS 621

Query: 145 FQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           F GL  +  L++  N  +++ PG FD L +L  ++L      C+C+L WL  W + + +
Sbjct: 622 FIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRI 680



 Score = 83.1 bits (202), Expect = 3e-14
 Identities = 49/151 (32%), Positives = 74/151 (48%), Gaps = 1/151 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN+I+ L   +F GL  L  L L  N I+ +    F GL  L+ L L+ N+I CL  +
Sbjct: 335 LSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVD 394

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            FQ L  L  L++  N   ++  G F  L A++ + L      CDCHL+WL  +     +
Sbjct: 395 AFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPI 454

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
           + S    C  P  L  + +G ++  +  C G
Sbjct: 455 ETS-GARCTSPRRLANKRIGQIKSKKFRCSG 484



 Score = 79.6 bits (193), Expect = 3e-13
 Identities = 44/137 (32%), Positives = 73/137 (53%), Gaps = 1/137 (0%)

Query: 103 LEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFS 162
           L  +DL NN IST+   +F  + +L  L LS NR+ C+   TF GL  L  L++ GN  S
Sbjct: 775 LTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDIS 834

Query: 163 SLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQAL 222
            +  G F++L AL  + +G   L CDC+++WL  W ++   +      CA P  +  + L
Sbjct: 835 VVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKE-PGIARCAGPGEMADKLL 893

Query: 223 GSLQEAQLCCEGALELH 239
            +    +  C+G ++++
Sbjct: 894 LTTPSKKFTCQGPVDVN 910



 Score = 53.1 bits (125), Expect = 3e-05
 Identities = 38/108 (35%), Positives = 56/108 (51%), Gaps = 4/108 (3%)

Query: 81  TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 140
           TL+L +N+IT + N SF+GLS +  L L +N I+TV PGAF  L  L  L+L  N   C 
Sbjct: 606 TLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCN 665

Query: 141 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCD 188
               + G     +  ++GN     +P    E+P   + D+  +  TCD
Sbjct: 666 CYLAWLGEWLRKKRIVTGNP-RCQKPYFLKEIP---IQDVAIQDFTCD 709



 Score = 38.3 bits (87), Expect = 0.79
 Identities = 23/60 (38%), Positives = 31/60 (51%)

Query: 80  VTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           +TL+LS N++  +   +F GL  L  L L  N IS V  GAF  L  L  L +  N + C
Sbjct: 800 LTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYC 859



>ref|NP_034016.1| (NM_009886) cadherin EGF LAG seven-pass G-type receptor [Mus
            musculus]
 pir||T14119 seven-pass transmembrane receptor protein precursor - mouse
 gb|AAC68836.1| (AF031572) seven-pass transmembrane receptor precursor [Mus musculus]
          Length = 3034

 Score = 88.5 bits (216), Expect = 6e-16
 Identities = 73/279 (26%), Positives = 121/279 (43%), Gaps = 25/279 (8%)

Query: 667  VATPVIFAGTSGCGV---GNLTEPVAV--SLRHWAEGAEPVAAWWSQE-GPGEAGGWTSE 720
            + TPV+ A     G     +L  P+ V  SL    E ++PV  +W+     G  GGW+++
Sbjct: 2385 INTPVVSAMVYSEGTPLPSSLQRPILVEFSLLETEERSKPVCVFWNHSLDTGGTGGWSAK 2444

Query: 721  GCQLRSSQPNVSALHCQHLGNVAVLMELSAFPREVGGAGAGLHPVVYPXXXXXXXXXXXX 780
            GC+L S         C H  + AVLM++S   R   G    L  + Y             
Sbjct: 2445 GCELLSRNRTHVTCQCSHSASCAVLMDIS---RREHGEVLPLKIITY---AALSLSLVAL 2498

Query: 781  XXTYILNHSSIRVSRKGWHML-LNLCFHIAMTSAVFAGGITLTNYQMVCQAVGITLHYSS 839
               ++L  S +R  R   H +  NL   +  +  +F  GI  T    +C  V I LHY S
Sbjct: 2499 LVAFVL-LSLVRTLRSNLHSIHKNLIAALFFSQLIFMVGINQTENPFLCTVVAILLHYVS 2557

Query: 840  LSTLLWMGVKARVLHKELTWRAPPPQEGDPALPTPSPMLRFYLIAGGIPLIICGITAAVN 899
            + T  W  V+   +++ LT         +       PM  ++++  GIP I+ G+   ++
Sbjct: 2558 MGTFAWTLVENLHVYRMLT---------EVRNIDTGPMRFYHVVGWGIPAIVTGLAVGLD 2608

Query: 900  IHNYRDHSPYCWLVWRPSL-GAFYIPVALILLITWIYFL 937
               Y  +  +CWL  + +L  +F  PV  +++I  + F+
Sbjct: 2609 PQGY-GNPDFCWLSLQDTLIWSFAGPVGTVIIINTVIFV 2646



>ref|NP_112611.1| (NM_031321) slit (Drosophila) homolog 3 [Rattus norvegicus]
 pir||T13953 MEGF5 protein - rat
 dbj|BAA32461.1| (AB011531) MEGF5 [Rattus norvegicus]
          Length = 1523

 Score = 88.5 bits (216), Expect = 6e-16
 Identities = 49/151 (32%), Positives = 80/151 (52%), Gaps = 1/151 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN+I  +R G+F G + +++L L  N + T+    F GL  LK L L +N I C+ ++
Sbjct: 564 LSNNRIKEVREGAFDGAAGVQELMLTGNQLETMHGRMFRGLSGLKTLMLRSNLISCVNND 623

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           TF GL  +  L++  N  +++ PG F  L +L  ++L +    C+CH+ WL  W + R +
Sbjct: 624 TFAGLSSVRLLSLYDNRITTISPGAFTTLVSLSTINLLSNPFNCNCHMAWLGRWLRKRRI 683

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
            +S +  C  P  L    +  +      CEG
Sbjct: 684 -VSGNPRCQKPFFLKEIPIQDVAIQDFTCEG 713



 Score = 86.6 bits (211), Expect = 2e-15
 Identities = 59/229 (25%), Positives = 92/229 (39%), Gaps = 25/229 (10%)

Query: 30  CPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSXXXXXXXXXXXXXXNGTVTLLLSNNKI 89
           C  S  S  C G   + +  G+P  A R  +                     L L +N++
Sbjct: 38  CTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFTGLKNLRVLHLEDNQV 97

Query: 90  TGLRNGSFLGLSLLEKL------------------------DLRNNIISTVQPGAFLGLG 125
           + +  G+F  L  LE+L                        DL  N I  +   AF G+ 
Sbjct: 98  SVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGVT 157

Query: 126 ELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFL 185
            +K L L NN I C+    F+ L  L  L ++ N  S +    F+ +P ++ + L +  L
Sbjct: 158 GVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217

Query: 186 TCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
            CDCHL WL  W + R   + + TLC  P  L   ++  +Q+ +  C G
Sbjct: 218 YCDCHLAWLSDWLRQRR-TIGQFTLCMAPVHLRGFSVADVQKKEYVCPG 265



 Score = 84.3 bits (205), Expect = 1e-14
 Identities = 47/152 (30%), Positives = 78/152 (50%), Gaps = 1/152 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           +S N+I+ +   +F GL  L  L L  N I+ +  G F GL  L+ L L+ N+I CL   
Sbjct: 338 ISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIPKGLFDGLVSLQLLLLNANKINCLRVN 397

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           TFQ L  L  L++  N   ++  G+F  L +++ + L      CDCHL+WL  + Q+  +
Sbjct: 398 TFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPI 457

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEGA 235
           + S    C+ P  L  + +  ++  +  C G+
Sbjct: 458 ETS-GARCSSPRRLANKRISQIKSKKFRCSGS 488



 Score = 74.1 bits (179), Expect = 1e-11
 Identities = 50/160 (31%), Positives = 78/160 (48%), Gaps = 6/160 (3%)

Query: 82  LLLSNNKITGLRN--GSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           L L  N +T +     +F  L+L+   DL NN IS +    F  +  L  L LS NR+ C
Sbjct: 757 LYLEGNHLTAVPKELSTFRQLTLI---DLSNNSISMLTNHTFSNMSHLSTLILSYNRLRC 813

Query: 140 LTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQ 199
           +    F GL  L  L + GN  SS+  G F++L +L  + LG   L CDC LRWL  W +
Sbjct: 814 IPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGINPLHCDCSLRWLSEWIK 873

Query: 200 NRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELH 239
               +      C+ P ++  + L +    +  C+G ++++
Sbjct: 874 -AGYKEPGIARCSSPESMADRLLLTTPTHRFQCKGPVDIN 912



 Score = 53.1 bits (125), Expect = 3e-05
 Identities = 36/112 (32%), Positives = 57/112 (50%), Gaps = 4/112 (3%)

Query: 77  NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 136
           +G  TL+L +N I+ + N +F GLS +  L L +N I+T+ PGAF  L  L  ++L +N 
Sbjct: 605 SGLKTLMLRSNLISCVNNDTFAGLSSVRLLSLYDNRITTISPGAFTTLVSLSTINLLSNP 664

Query: 137 IGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCD 188
             C     + G     R  +SGN     +P    E+P   + D+  +  TC+
Sbjct: 665 FNCNCHMAWLGRWLRKRRIVSGNP-RCQKPFFLKEIP---IQDVAIQDFTCE 712



 Score = 36.7 bits (83), Expect = 2.3
 Identities = 23/59 (38%), Positives = 31/59 (51%)

Query: 81  TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           TL+LS N++  +   +F GL  L  L L  N IS+V  G+F  L  L  L L  N + C
Sbjct: 803 TLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGINPLHC 861



>gb|AAD44760.1|AF144629_1 (AF144629) SLIT3 [Mus musculus]
          Length = 1523

 Score = 88.2 bits (215), Expect = 8e-16
 Identities = 48/151 (31%), Positives = 81/151 (52%), Gaps = 1/151 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN+I  +R G+F G + +++L L  N + T+    F GL  LK L L +N I C++++
Sbjct: 564 LSNNRIKEVREGAFDGAASVQELMLTGNQLETMHGRMFRGLSGLKTLMLRSNLISCVSND 623

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           TF GL  +  L++  N  +++ PG F  L +L  ++L +    C+CH+ WL  W + R +
Sbjct: 624 TFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHMAWLGRWLRKRRI 683

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
            +S +  C  P  L    +  +      C+G
Sbjct: 684 -VSGNPRCQKPFFLKEIPIQDVAIQDFTCDG 713



 Score = 86.2 bits (210), Expect = 3e-15
 Identities = 59/229 (25%), Positives = 92/229 (39%), Gaps = 25/229 (10%)

Query: 30  CPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSXXXXXXXXXXXXXXNGTVTLLLSNNKI 89
           C  S  S  C G   + +  G+P  A R  +                     L L +N++
Sbjct: 38  CTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQV 97

Query: 90  TGLRNGSFLGLSLLEKL------------------------DLRNNIISTVQPGAFLGLG 125
           + +  G+F  L  LE+L                        DL  N I  +   AF G+ 
Sbjct: 98  SIIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGVT 157

Query: 126 ELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFL 185
            +K L L NN I C+    F+ L  L  L ++ N  S +    F+ +P ++ + L +  L
Sbjct: 158 GVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217

Query: 186 TCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
            CDCHL WL  W + R   + + TLC  P  L   ++  +Q+ +  C G
Sbjct: 218 YCDCHLAWLSDWLRQRR-TIGQFTLCMAPVHLRGFSVADVQKKEYVCPG 265



 Score = 83.9 bits (204), Expect = 2e-14
 Identities = 47/152 (30%), Positives = 78/152 (50%), Gaps = 1/152 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           +S N+I+ +   +F GL  L  L L  N I+ +  G F GL  L+ L L+ N+I CL   
Sbjct: 338 ISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIPKGLFDGLVSLQLLLLNANKINCLRVN 397

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           TFQ L  L  L++  N   ++  G+F  L +++ + L      CDCHL+WL  + Q+  +
Sbjct: 398 TFQDLQNLNLLSLYDNKLQTISKGLFVPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPI 457

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEGA 235
           + S    C+ P  L  + +  ++  +  C G+
Sbjct: 458 ETS-GARCSSPRRLANKRISQIKSKKFRCSGS 488



 Score = 76.9 bits (186), Expect = 2e-12
 Identities = 51/160 (31%), Positives = 79/160 (48%), Gaps = 6/160 (3%)

Query: 82  LLLSNNKITGLRN--GSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           L L  N +T +     +F  L+L+   DL NN IS +    F  +  L  L LS NR+ C
Sbjct: 757 LYLEGNHLTAVPKELSAFRQLTLI---DLSNNSISMLTNHTFSNMSHLSTLILSYNRLRC 813

Query: 140 LTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQ 199
           +    F GL  L  L + GN  SS+  G F++L +L  + LGT  L CDC LRWL  W +
Sbjct: 814 IPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVK 873

Query: 200 NRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELH 239
               +      C+ P ++  + L +    +  C+G ++++
Sbjct: 874 -AGYKEPGIARCSSPESMADRLLLTTPTHRFQCKGPVDIN 912



 Score = 53.9 bits (127), Expect = 2e-05
 Identities = 37/112 (33%), Positives = 57/112 (50%), Gaps = 4/112 (3%)

Query: 77  NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNR 136
           +G  TL+L +N I+ + N +F GLS +  L L +N I+T+ PGAF  L  L  ++L +N 
Sbjct: 605 SGLKTLMLRSNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNP 664

Query: 137 IGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCD 188
             C     + G     R  +SGN     +P    E+P   + D+  +  TCD
Sbjct: 665 FNCNCHMAWLGRWLRKRRIVSGNP-RCQKPFFLKEIP---IQDVAIQDFTCD 712



 Score = 37.9 bits (86), Expect = 1.0
 Identities = 23/59 (38%), Positives = 31/59 (51%)

Query: 81  TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           TL+LS N++  +   +F GL  L  L L  N IS+V  G+F  L  L  L L  N + C
Sbjct: 803 TLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHC 861



>ref|NP_055061.1| (NM_014246) cadherin EGF LAG seven-pass G-type receptor 1; cadherin
            EGF LAG seven-pass G-type receptor 1, flamingo
            (Drosophila) homolog; protocadherin flamingo 2 [Homo
            sapiens]
 ref|XP_010054.1| (XM_010054) cadherin EGF LAG seven-pass G-type receptor 1 [Homo
            sapiens]
 gb|AAF61930.1|AF231024_1 (AF231024) protocadherin Flamingo 2 [Homo sapiens]
          Length = 3014

 Score = 87.8 bits (214), Expect = 1e-15
 Identities = 69/256 (26%), Positives = 113/256 (43%), Gaps = 22/256 (8%)

Query: 684  LTEPVAV--SLRHWAEGAEPVAAWWSQE-GPGEAGGWTSEGCQLRSSQPNVSALHCQHLG 740
            L  PV V  +L    E  +PV  +W+     G  GGW++ GC+L S      A  C H  
Sbjct: 2390 LERPVLVEFALLEVEERTKPVCVFWNHSLAVGGTGGWSARGCELLSRNRTHVACQCSHTA 2449

Query: 741  NVAVLMELSAFPREVGGAGAGLHPVVYPXXXXXXXXXXXXXXTYILNHSSIRVSRKGWHM 800
            + AVLM++S   R   G    L  V Y                ++L  S +R+ R   H 
Sbjct: 2450 SFAVLMDIS---RRENGEVLPLKIVTY---AAVSLSLAALLVAFVL-LSLVRMLRSNLHS 2502

Query: 801  L-LNLCFHIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTW 859
            +  +L   + ++  VF  GI  T    +C  V I LHY  +ST  W  V++  +++ LT 
Sbjct: 2503 IHKHLAVALFLSQLVFVIGINQTENPFLCTVVAILLHYIYMSTFAWTLVESLHVYRMLT- 2561

Query: 860  RAPPPQEGDPALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSL- 918
                    +       PM  +Y++  GIP I+ G+   ++   Y  +  +CWL  + +L 
Sbjct: 2562 --------EVRNIDTGPMRFYYVVGWGIPAIVTGLAVGLDPQGY-GNPDFCWLSLQDTLI 2612

Query: 919  GAFYIPVALILLITWI 934
             +F  P+  +++I  +
Sbjct: 2613 WSFAGPIGAVIIINTV 2628



>emb|CAB38413.1| (AL031588) dJ1163J1.1 (mostly supported by GENSCAN, FGENES and
            GENEWISE) [Homo sapiens]
          Length = 1477

 Score = 87.8 bits (214), Expect = 1e-15
 Identities = 69/256 (26%), Positives = 113/256 (43%), Gaps = 22/256 (8%)

Query: 684  LTEPVAV--SLRHWAEGAEPVAAWWSQE-GPGEAGGWTSEGCQLRSSQPNVSALHCQHLG 740
            L  PV V  +L    E  +PV  +W+     G  GGW++ GC+L S      A  C H  
Sbjct: 853  LERPVLVEFALLEVEERTKPVCVFWNHSLAVGGTGGWSARGCELLSRNRTHVACQCSHTA 912

Query: 741  NVAVLMELSAFPREVGGAGAGLHPVVYPXXXXXXXXXXXXXXTYILNHSSIRVSRKGWHM 800
            + AVLM++S   R   G    L  V Y                ++L  S +R+ R   H 
Sbjct: 913  SFAVLMDIS---RRENGEVLPLKIVTY---AAVSLSLAALLVAFVL-LSLVRMLRSNLHS 965

Query: 801  L-LNLCFHIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTW 859
            +  +L   + ++  VF  GI  T    +C  V I LHY  +ST  W  V++  +++ LT 
Sbjct: 966  IHKHLAVALFLSQLVFVIGINQTENPFLCTVVAILLHYIYMSTFAWTLVESLHVYRMLT- 1024

Query: 860  RAPPPQEGDPALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSL- 918
                    +       PM  +Y++  GIP I+ G+   ++   Y  +  +CWL  + +L 
Sbjct: 1025 --------EVRNIDTGPMRFYYVVGWGIPAIVTGLAVGLDPQGY-GNPDFCWLSLQDTLI 1075

Query: 919  GAFYIPVALILLITWI 934
             +F  P+  +++I  +
Sbjct: 1076 WSFAGPIGAVIIINTV 1091



>dbj|BAB23775.1| (AK005049) putative [Mus musculus]
          Length = 570

 Score = 87.0 bits (212), Expect = 2e-15
 Identities = 55/156 (35%), Positives = 81/156 (51%), Gaps = 1/156 (0%)

Query: 78  GTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRI 137
           G + L LS N++  +  G+F  LS L  L L +N I+ +    F  L +L +L L +N +
Sbjct: 313 GLLHLSLSYNQLETIPEGAFTNLSRLVSLTLSHNAITDLPEHVFRNLEQLVKLSLDSNNL 372

Query: 138 GCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPW 197
             L    F  L RL  LN+S N  ++L  G+FD    L  + L      CDCHL +L  W
Sbjct: 373 TALHPALFHNLSRLQLLNLSRNQLTTLPGGIFDTNYDLFNLALLGNPWQCDCHLSYLTSW 432

Query: 198 AQNRSLQLSE-HTLCAYPSALHAQALGSLQEAQLCC 232
            +  + Q+S  HT CA P+ L  Q + +L++ QL C
Sbjct: 433 LRLYNNQISNTHTFCAGPAYLKGQLVPNLKQEQLIC 468



 Score = 52.7 bits (124), Expect = 4e-05
 Identities = 44/147 (29%), Positives = 67/147 (44%), Gaps = 5/147 (3%)

Query: 81  TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 140
           +L L  N++  L    F  L  L  L+L  N+++ +  GAF  L  L+ L LSNN +  L
Sbjct: 172 SLQLQGNQLRTLPGRLFQSLRDLRTLNLAQNLLTQLPKGAFQSLTGLQMLKLSNNMLARL 231

Query: 141 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQN 200
                  L  L  L + GN  + L P +F +L +L+++ L    +   CHL   L  + +
Sbjct: 232 PEGALGSLSSLQELFLDGNAITELSPHLFSQLFSLEMLWLQHNAI---CHLPVSLFSSLH 288

Query: 201 R--SLQLSEHTLCAYPSALHAQALGSL 225
               L L ++ L   P  L A   G L
Sbjct: 289 NLTFLSLKDNALRTLPEGLFAHNQGLL 315



 Score = 47.6 bits (111), Expect = 0.001
 Identities = 30/104 (28%), Positives = 50/104 (47%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L ++ + ++ L    F  LS LEKL L  + ++ +    F  +  L+ L L  N++  L 
Sbjct: 125 LEITGSPVSNLSAHIFSNLSSLEKLTLDFDRLAGLPEDLFCHMDILESLQLQGNQLRTLP 184

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFL 185
              FQ L  L  LN++ N+ + L  G F  L  L+++ L    L
Sbjct: 185 GRLFQSLRDLRTLNLAQNLLTQLPKGAFQSLTGLQMLKLSNNML 228



 Score = 43.4 bits (100), Expect = 0.024
 Identities = 38/122 (31%), Positives = 57/122 (46%), Gaps = 12/122 (9%)

Query: 114 STVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELP 173
           +TV+  AF G   L ++   N ++  L  + F GLPRL  L I+G+  S+L   +F  L 
Sbjct: 85  TTVRTRAFSGSPNLTKVVFLNTQVRHLEPDAFGGLPRLQDLEITGSPVSNLSAHIFSNLS 144

Query: 174 ALKVVDLGTEFLT-----CDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEA 228
           +L+ + L  + L        CH+  L       SLQL  + L   P  L  Q+L  L+  
Sbjct: 145 SLEKLTLDFDRLAGLPEDLFCHMDIL------ESLQLQGNQLRTLPGRLF-QSLRDLRTL 197

Query: 229 QL 230
            L
Sbjct: 198 NL 199



>gb|AAD44759.1|AF144628_1 (AF144628) SLIT2 [Mus musculus]
          Length = 1521

 Score = 87.0 bits (212), Expect = 2e-15
 Identities = 52/165 (31%), Positives = 78/165 (46%), Gaps = 5/165 (3%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L+ N +       FLG + L +LDL  N I  +   AF G  ++K L L  N+I C+ 
Sbjct: 108 LRLNRNNLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 167

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+ L  L  L ++ N  + L    F+ +P L+   L +  L CDCHL WL  W + R
Sbjct: 168 DGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQR 227

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPS 246
             ++  +T C  PS L    +  +Q+ +  C G    H   + PS
Sbjct: 228 P-RVGLYTQCMGPSHLRGHNVAEVQKREFVCSG----HQSFMAPS 267



 Score = 86.6 bits (211), Expect = 2e-15
 Identities = 44/119 (36%), Positives = 69/119 (57%)

Query: 85  SNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSET 144
           SNNKIT +  G+F G S + ++ L +N +  VQ   F GL  LK L L +NRI C+ +++
Sbjct: 558 SNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDS 617

Query: 145 FQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           F GL  +  L++  N  +++ PG FD L +L  ++L      C+CHL WL  W + + +
Sbjct: 618 FIGLGSVRLLSLYDNQITTVAPGAFDSLHSLSTLNLLANPFNCNCHLAWLGEWLRRKRI 676



 Score = 82.7 bits (201), Expect = 3e-14
 Identities = 49/151 (32%), Positives = 74/151 (48%), Gaps = 1/151 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN+I+ L   +F GL  L  L L  N I+ +    F GL  L+ L L+ N+I CL  +
Sbjct: 331 LSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVD 390

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            FQ L  L  L++  N   ++  G F  L A++ + L      CDCHL+WL  +     +
Sbjct: 391 AFQDLHNLNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWLADYLHTNPI 450

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
           + S    C  P  L  + +G ++  +  C G
Sbjct: 451 ETS-GARCTSPRRLANKRIGQIKSKKFRCSG 480



 Score = 79.6 bits (193), Expect = 3e-13
 Identities = 44/136 (32%), Positives = 72/136 (52%), Gaps = 1/136 (0%)

Query: 103 LEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFS 162
           L  +DL NN IST+   +F  + +L  L LS NR+ C+   TF GL  L  L++ GN  S
Sbjct: 771 LTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDIS 830

Query: 163 SLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQAL 222
            +  G F++L AL  + +G   L CDC+++WL  W ++   +      CA P  +  + L
Sbjct: 831 VVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKE-PGIARCAGPGEMADKLL 889

Query: 223 GSLQEAQLCCEGALEL 238
            +    +  C+G +++
Sbjct: 890 LTTPSKKFTCQGPVDI 905



 Score = 38.3 bits (87), Expect = 0.79
 Identities = 23/60 (38%), Positives = 31/60 (51%)

Query: 80  VTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           +TL+LS N++  +   +F GL  L  L L  N IS V  GAF  L  L  L +  N + C
Sbjct: 796 LTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYC 855



>gb|AAD04309.1| (AF055585) neurogenic extracellular slit protein Slit2 [Homo
           sapiens]
          Length = 1521

 Score = 86.6 bits (211), Expect = 2e-15
 Identities = 52/165 (31%), Positives = 78/165 (46%), Gaps = 5/165 (3%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L+ N +       FLG + L +LDL  N I  +   AF G  ++K L L  N+I C+ 
Sbjct: 108 LRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 167

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+ L  L  L ++ N  + L    F+ +P L+   L +  L CDCHL WL  W + R
Sbjct: 168 DGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQR 227

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPS 246
             ++  +T C  PS L    +  +Q+ +  C G    H   + PS
Sbjct: 228 P-RVGLYTQCMGPSHLRGHNVAEVQKREFVCSG----HQSFMAPS 267



 Score = 83.1 bits (202), Expect = 3e-14
 Identities = 49/151 (32%), Positives = 74/151 (48%), Gaps = 1/151 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN+I+ L   +F GL  L  L L  N I+ +    F GL  L+ L L+ N+I CL  +
Sbjct: 331 LSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVD 390

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            FQ L  L  L++  N   ++  G F  L A++ + L      CDCHL+WL  +     +
Sbjct: 391 AFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPI 450

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
           + S    C  P  L  + +G ++  +  C G
Sbjct: 451 ETS-GARCTSPRRLANKRIGQIKSKKFRCSG 480



 Score = 80.4 bits (195), Expect = 2e-13
 Identities = 41/119 (34%), Positives = 69/119 (57%)

Query: 85  SNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSET 144
           SNNKIT +  G+F G S + ++ L +N +  VQ   F GL + + L L +NRI C+ +++
Sbjct: 558 SNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLEKPQNLMLRSNRITCVGNDS 617

Query: 145 FQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           F GL  +  L++  N  +++ PG FD L +L  ++L      C+C+L WL  W + + +
Sbjct: 618 FIGLSSVRMLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRI 676



 Score = 79.6 bits (193), Expect = 3e-13
 Identities = 44/137 (32%), Positives = 73/137 (53%), Gaps = 1/137 (0%)

Query: 103 LEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFS 162
           L  +DL NN IST+   +F  + +L  L LS NR+ C+   TF GL  L  L++ GN  S
Sbjct: 771 LTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDIS 830

Query: 163 SLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQAL 222
            +  G F++L AL  + +G   L CDC+++WL  W ++   +      CA P  +  + L
Sbjct: 831 VVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKE-PGIARCAGPGEMADKLL 889

Query: 223 GSLQEAQLCCEGALELH 239
            +    +  C+G ++++
Sbjct: 890 LTTPSKKFTCQGPVDVN 906



 Score = 51.5 bits (121), Expect = 8e-05
 Identities = 37/107 (34%), Positives = 55/107 (50%), Gaps = 4/107 (3%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L+L +N+IT + N SF+GLS +  L L +N I+TV PGAF  L  L  L+L  N   C  
Sbjct: 603 LMLRSNRITCVGNDSFIGLSSVRMLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNC 662

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCD 188
              + G     +  ++GN     +P    E+P   + D+  +  TCD
Sbjct: 663 YLAWLGEWLRKKRIVTGNP-RCQKPYFLKEIP---IQDVAIQDFTCD 705



 Score = 38.3 bits (87), Expect = 0.79
 Identities = 23/60 (38%), Positives = 31/60 (51%)

Query: 80  VTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           +TL+LS N++  +   +F GL  L  L L  N IS V  GAF  L  L  L +  N + C
Sbjct: 796 LTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYC 855



>ref|NP_004778.1| (NM_004787) slit (Drosophila) homolog 2 [Homo sapiens]
 ref|XP_039646.1| (XM_039646) slit (Drosophila) homolog 2 [Homo sapiens]
 dbj|BAA35185.1| (AB017168) Slit-2 protein [Homo sapiens]
          Length = 1529

 Score = 86.6 bits (211), Expect = 2e-15
 Identities = 52/165 (31%), Positives = 78/165 (46%), Gaps = 5/165 (3%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L+ N +       FLG + L +LDL  N I  +   AF G  ++K L L  N+I C+ 
Sbjct: 108 LRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 167

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
              F+ L  L  L ++ N  + L    F+ +P L+   L +  L CDCHL WL  W + R
Sbjct: 168 DGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQR 227

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPS 246
             ++  +T C  PS L    +  +Q+ +  C G    H   + PS
Sbjct: 228 P-RVGLYTQCMGPSHLRGHNVAEVQKREFVCSG----HQSFMAPS 267



 Score = 83.5 bits (203), Expect = 2e-14
 Identities = 43/119 (36%), Positives = 69/119 (57%)

Query: 85  SNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSET 144
           SNNKIT +  G+F G S + ++ L +N +  VQ   F GL  LK L L +NRI C+ +++
Sbjct: 566 SNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDS 625

Query: 145 FQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           F GL  +  L++  N  +++ PG FD L +L  ++L      C+C+L WL  W + + +
Sbjct: 626 FIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRI 684



 Score = 80.8 bits (196), Expect = 1e-13
 Identities = 48/149 (32%), Positives = 73/149 (48%), Gaps = 1/149 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN+I+ L   +F GL  L  L L  N I+ +    F GL  L+ L L+ N+I CL  +
Sbjct: 331 LSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVD 390

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
            FQ L  L  L++  N   ++  G F  L A++ + L      CDCHL+WL  +     +
Sbjct: 391 AFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPI 450

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCC 232
           + S    C  P  L  + +G ++  +  C
Sbjct: 451 ETS-GARCTSPRRLANKRIGQIKSKKFRC 478



 Score = 79.6 bits (193), Expect = 3e-13
 Identities = 44/137 (32%), Positives = 73/137 (53%), Gaps = 1/137 (0%)

Query: 103 LEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFS 162
           L  +DL NN IST+   +F  + +L  L LS NR+ C+   TF GL  L  L++ GN  S
Sbjct: 779 LTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDIS 838

Query: 163 SLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQAL 222
            +  G F++L AL  + +G   L CDC+++WL  W ++   +      CA P  +  + L
Sbjct: 839 VVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKE-PGIARCAGPGEMADKLL 897

Query: 223 GSLQEAQLCCEGALELH 239
            +    +  C+G ++++
Sbjct: 898 LTTPSKKFTCQGPVDVN 914



 Score = 53.1 bits (125), Expect = 3e-05
 Identities = 38/108 (35%), Positives = 56/108 (51%), Gaps = 4/108 (3%)

Query: 81  TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 140
           TL+L +N+IT + N SF+GLS +  L L +N I+TV PGAF  L  L  L+L  N   C 
Sbjct: 610 TLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCN 669

Query: 141 TSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCD 188
               + G     +  ++GN     +P    E+P   + D+  +  TCD
Sbjct: 670 CYLAWLGEWLRKKRIVTGNP-RCQKPYFLKEIP---IQDVAIQDFTCD 713



 Score = 38.3 bits (87), Expect = 0.79
 Identities = 23/60 (38%), Positives = 31/60 (51%)

Query: 80  VTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           +TL+LS N++  +   +F GL  L  L L  N IS V  GAF  L  L  L +  N + C
Sbjct: 804 LTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYC 863



>gb|AAL02123.1| (AY046070) Slit [Xenopus laevis]
          Length = 1530

 Score = 86.2 bits (210), Expect = 3e-15
 Identities = 50/160 (31%), Positives = 74/160 (46%), Gaps = 1/160 (0%)

Query: 82  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 141
           L L+ N +       FLG   L +LDL  N I  +   AF G  ++K L L  N+I C+ 
Sbjct: 117 LRLNRNNLQVFPELLFLGTPKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 176

Query: 142 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNR 201
             TF+ L  L  L ++ N  + L    F+ +P L+   L +  L CDCHL WL  W + R
Sbjct: 177 DGTFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQR 236

Query: 202 SLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTH 241
             ++  +T C  P  L    +  +Q+ +  C G      H
Sbjct: 237 P-RVGLYTQCMGPIHLRGHNVAEVQKREFSCTGQQSFMVH 275



 Score = 85.0 bits (207), Expect = 7e-15
 Identities = 49/151 (32%), Positives = 76/151 (49%), Gaps = 1/151 (0%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNN+I+ +   +F GL  L  L L  N I+ +  G F GL  L+ L L+ N+I CL  +
Sbjct: 340 LSNNQISEIAADAFQGLRSLNSLVLYGNKITELPKGLFEGLFSLQLLLLNANKINCLRVD 399

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           +FQ L  L  L++  N   ++  G F  L A++ + L      CDCHL+WL  +     +
Sbjct: 400 SFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTLHLAQNPFICDCHLKWLADYLHTNPI 459

Query: 204 QLSEHTLCAYPSALHAQALGSLQEAQLCCEG 234
           + S    C  P  L  + +G ++  +  C G
Sbjct: 460 ETS-GARCTSPRRLANKRIGQIKSKKFRCSG 489



 Score = 84.7 bits (206), Expect = 9e-15
 Identities = 43/120 (35%), Positives = 69/120 (56%)

Query: 84  LSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSE 143
           LSNNKIT +  G+F G + + +L L +N +  V+   F GL  LK L L +N I C+ ++
Sbjct: 566 LSNNKITDIEEGAFEGANGVNELLLTSNRMENVRHKMFKGLEGLKTLMLRSNHISCVNND 625

Query: 144 TFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSL 203
           +F GL  +  L++  N  +++ PG FD L +L  ++L      C+CHL WL  W + + +
Sbjct: 626 SFTGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCHLAWLGDWLRKKRI 685



 Score = 71.4 bits (172), Expect = 9e-11
 Identities = 41/137 (29%), Positives = 68/137 (48%), Gaps = 1/137 (0%)

Query: 103 LEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFS 162
           L  +DL NN IST+   +F  +  L  L LS NR+ C+    F  L  L  L++ GN  S
Sbjct: 780 LTLIDLSNNQISTLSNHSFSNMTHLLTLILSYNRLRCIPLRAFDRLKSLKLLSLHGNDVS 839

Query: 163 SLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQAL 222
           ++  G F +L AL  + +G   L CDC ++WL  W ++   +      C+ P  +  + L
Sbjct: 840 AIPEGAFSDLSALSHLAIGANPLYCDCKMQWLSDWVKSEYKE-PGIARCSGPGEMADKLL 898

Query: 223 GSLQEAQLCCEGALELH 239
            +    +  C G ++++
Sbjct: 899 LTTPSKKFSCNGPVDVN 915



 Score = 34.8 bits (78), Expect = 9.0
 Identities = 20/60 (33%), Positives = 31/60 (51%)

Query: 80  VTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGC 139
           +TL+LS N++  +   +F  L  L+ L L  N +S +  GAF  L  L  L +  N + C
Sbjct: 805 LTLILSYNRLRCIPLRAFDRLKSLKLLSLHGNDVSAIPEGAFSDLSALSHLAIGANPLYC 864



  Database: nr
    Posted date:  Jan 6, 2002  7:56 PM
  Number of letters in database: 257,180,598
  Number of sequences in database:  808,980
  
Lambda     K      H
   0.320    0.136    0.425 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 596749400
Number of Sequences: 808980
Number of extensions: 23264191
Number of successful extensions: 62111
Number of sequences better than 10.0: 1225
Number of HSP's better than 10.0 without gapping: 863
Number of HSP's successfully gapped in prelim test: 378
Number of HSP's that attempted gapping in prelim test: 53530
Number of HSP's gapped (non-prelim): 6427
length of query: 1331
length of database: 257,180,598
effective HSP length: 57
effective length of query: 1274
effective length of database: 211,068,738
effective search space: 268901572212
effective search space used: 268901572212
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 78 (34.8 bits)








  
 
    Home  
     Initium  
     Angiogenesis
 
        
      
 
    
   
       
      
   
       
 
   
       
FAQ