Score E
Sequences producing significant alignments: (bits) Value
sp|P08253|COG2_HUMAN 72 KD TYPE IV COLLAGENASE PRECURSOR (7... 1356 0.0
gb|AAA35701.1| (J03210) collagenase type IV precursor [Homo... 1336 0.0
pdb|1CK7|A Chain A, Gelatinase A (Full-Length) 1334 0.0
ref|NP_032636.1| matrix metalloproteinase 2; gelatinase A; ... 1316 0.0
sp|P33436|COG2_RAT 72 KD TYPE IV COLLAGENASE PRECURSOR (72 ... 1313 0.0
gb|AAB41692.1| (U65656) gelatinase A [Rattus norvegicus] 1310 0.0
gb|AAF67517.1|AF177217_1 (AF177217) matrix metalloproteinas... 1307 0.0
sp|P50757|COG2_RABIT 72 KD TYPE IV COLLAGENASE PRECURSOR (7... 1306 0.0
gb|AAG28169.1|AF290428_1 (AF290428) matrix metalloprotease ... 1299 0.0
sp|Q90611|COG2_CHICK 72 KD TYPE IV COLLAGENASE PRECURSOR (7... 1181 0.0
dbj|BAA85769.2| (AB033754) gelatinase A [Oryzias latipes] 1042 0.0
dbj|BAA78479.1| (AB021698) matrix metalloproteinase-2 [Onco... 1039 0.0
emb|CAB46656.1| (AJ243311) matrix metalloproteinase-2 [Equu... 782 0.0
dbj|BAA85770.1| (AB033755) gelatinase B [Oryzias latipes] 671 0.0
gb|AAD41624.1|AF072455_1 (AF072455) gelatinase B [Xenopus l... 658 0.0
dbj|BAA11523.1| (D82052) gelatinase-b [Cynops pyrrhogaster] 650 0.0
sp|P41246|COG9_RABIT 92 KDA TYPE IV COLLAGENASE PRECURSOR (... 549 e-155
emb|CAC10459.1| (AL162458) bA465L10.4 (matrix metalloprotei... 540 e-152
pir||A34458 gelatinase B (EC 3.4.24.35) precursor - human 540 e-152
ref|NP_004985.1| matrix metalloproteinase 9 (gelatinase B, ... 540 e-152
gb|AAD50275.1| (AF169244) matrix metalloproteinase-9 [Canis... 533 e-150
dbj|BAA22087.3| (AB006421) matrix metalloproteinase-9 [Cani... 532 e-150
gb|AAB81681.1| (U89842) gelatinase B [Canis familiaris] 531 e-149
pir||I52580 gelatinase B (EC 3.4.24.35) precursor - mouse >... 529 e-149
ref|NP_038627.1| matrix metalloproteinase 9; Gel B; gelatin... 529 e-149
sp|P41245|COG9_MOUSE 92 KDA TYPE IV COLLAGENASE PRECURSOR (... 529 e-149
pir||JC1456 gelatinase B (EC 3.4.24.35) precursor - mouse >... 529 e-149
sp|O18733|COG9_CANFA 92 KDA TYPE IV COLLAGENASE PRECURSOR (... 527 e-148
sp|P52176|COG9_BOVIN 92 KDA TYPE IV COLLAGENASE PRECURSOR (... 525 e-148
pir||JC4364 gelatinase B (EC 3.4.24.35) precursor - rat >gi... 524 e-147
pir||S62907 gelatinase A (EC 3.4.24.24) precursor - rat 517 e-145
sp|P50282|COG9_RAT 92 KDA TYPE IV COLLAGENASE PRECURSOR (92... 517 e-145
emb|CAA51315.1| (X72795) gelatinase b [Mus musculus] 467 e-130
pdb|1GEN| C-Terminal Domain Of Gelatinase A 430 e-119
pdb|1RTG| C-Terminal Domain (Haemopexin-Like Domain) Of H... 415 e-115
dbj|BAA96389.1| (AB043996) MMP-9 [Bos taurus] 342 6e-93
dbj|BAA96387.1| (AB043994) MMP-2 [Bos taurus] 342 7e-93
gb|AAD26635.1| (AF111100) matrix metalloproteinase-2 precur... 332 8e-90
gb|AAD30283.1| (AF135231) MMP-2 protein [Bos taurus] 324 2e-87
gb|AAD27837.1|AF123396_1 (AF123396) gelatinase B [Canis fam... 285 1e-75
emb|CAA09079.1| (AJ010314) matrix metalloproteinase-2 [Equu... 244 3e-63
pdb|1QIB|A Chain A, Crystal Structure Of Gelatinase A Catal... 229 1e-58
sp|P07152|COGX_RAT STROMELYSIN-2 PRECURSOR (MATRIX METALLOP... 224 3e-57
ref|NP_062344.1| matrix metalloproteinase 10; stromelysin 2... 221 2e-56
gb|AAC34604.1| (AF070478) matrix metalloproteinase-13 [Gall... 219 1e-55
gb|AAF17559.1|AF201729_1 (AF201729) matrix metalloproteinas... 217 4e-55
sp|P28053|COG1_BOVIN INTERSTITIAL COLLAGENASE PRECURSOR (MA... 214 2e-54
ref|NP_002418.1| matrix metalloproteinase 13 (collagenase 3... 214 3e-54
sp|P28862|COG3_MOUSE STROMELYSIN-1 PRECURSOR (MATRIX METALL... 214 3e-54
ref|NP_034939.1| matrix metalloproteinase 3; progelatinase;... 214 3e-54
>sp|P08253|COG2_HUMAN 72 KD TYPE IV COLLAGENASE PRECURSOR (72 KD GELATINASE) (MATRIX
METALLOPROTEINASE-2) (MMP-2) (GELATINASE A) (TBE-1)
pir||A28153 gelatinase A (EC 3.4.24.24) precursor - human
gb|AAA52028.1| (M55593) type IV collagenase [Homo sapiens]
Length = 660
Score = 1356 bits (3471), Expect = 0.0
Identities = 629/660 (95%), Positives = 629/660 (95%)
Query: 1 MEALMARGALTGPXXXXXXXXXXXXXXXXXPSPIIKFPGDVAPKTDKELAVQYLNTFYGC 60
MEALMARGALTGP PSPIIKFPGDVAPKTDKELAVQYLNTFYGC
Sbjct: 1 MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGC 60
Query: 61 PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD 120
PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD
Sbjct: 61 PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD 120
Query: 121 KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD 180
KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
Sbjct: 121 KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD 180
Query: 181 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN 240
GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
Sbjct: 181 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN 240
Query: 241 GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT 300
GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT
Sbjct: 241 GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT 300
Query: 301 SYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY 360
SYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY
Sbjct: 301 SYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY 360
Query: 361 ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL 420
ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
Sbjct: 361 ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL 420
Query: 421 MAPIYTYTKNFRLSQDDIKGIQELYGASPDIDXXXXXXXXXXXXXXEICKQDIVFDGIAQ 480
MAPIYTYTKNFRLSQDDIKGIQELYGASPDID EICKQDIVFDGIAQ
Sbjct: 421 MAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQ 480
Query: 481 IRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEY 540
IRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEY
Sbjct: 481 IRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEY 540
Query: 541 WIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDP 600
WIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDP
Sbjct: 541 WIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDP 600
Query: 601 GFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
GFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
Sbjct: 601 GFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
>gb|AAA35701.1| (J03210) collagenase type IV precursor [Homo sapiens]
Length = 644
Score = 1336 bits (3420), Expect = 0.0
Identities = 616/630 (97%), Positives = 616/630 (97%)
Query: 31 PSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLD 90
PSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLD
Sbjct: 15 PSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLD 74
Query: 91 QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV 150
QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV
Sbjct: 75 QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV 134
Query: 151 WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD 210
WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD
Sbjct: 135 WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD 194
Query: 211 ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK 270
ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK
Sbjct: 195 ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK 254
Query: 271 YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG 330
YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG
Sbjct: 255 YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG 314
Query: 331 FCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFC 390
FCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFC
Sbjct: 315 FCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFC 374
Query: 391 PDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD 450
PDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD
Sbjct: 375 PDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD 434
Query: 451 IDXXXXXXXXXXXXXXEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVA 510
ID EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVA
Sbjct: 435 IDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVA 494
Query: 511 TFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDA 570
TFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDA
Sbjct: 495 TFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDA 554
Query: 571 AFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSY 630
AFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSY
Sbjct: 555 AFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSY 614
Query: 631 FFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
FFKGAYYLKLENQSLKSVKFGSIKSDWLGC
Sbjct: 615 FFKGAYYLKLENQSLKSVKFGSIKSDWLGC 644
>pdb|1CK7|A Chain A, Gelatinase A (Full-Length)
Length = 631
Score = 1334 bits (3414), Expect = 0.0
Identities = 615/630 (97%), Positives = 615/630 (97%)
Query: 31 PSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLD 90
PSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLD
Sbjct: 2 PSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLD 61
Query: 91 QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV 150
QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV
Sbjct: 62 QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV 121
Query: 151 WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD 210
WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD
Sbjct: 122 WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD 181
Query: 211 ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK 270
ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK
Sbjct: 182 ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK 241
Query: 271 YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG 330
YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG
Sbjct: 242 YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG 301
Query: 331 FCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFC 390
FCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFC
Sbjct: 302 FCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFC 361
Query: 391 PDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD 450
PDQGYSLFLVAAH FGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD
Sbjct: 362 PDQGYSLFLVAAHAFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD 421
Query: 451 IDXXXXXXXXXXXXXXEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVA 510
ID EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVA
Sbjct: 422 IDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVA 481
Query: 511 TFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDA 570
TFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDA
Sbjct: 482 TFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDA 541
Query: 571 AFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSY 630
AFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSY
Sbjct: 542 AFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSY 601
Query: 631 FFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
FFKGAYYLKLENQSLKSVKFGSIKSDWLGC
Sbjct: 602 FFKGAYYLKLENQSLKSVKFGSIKSDWLGC 631
>ref|NP_032636.1| matrix metalloproteinase 2; gelatinase A; 72kD gelatinase; 72kD
type IV collagenase [Mus musculus]
sp|P33434|COG2_MOUSE 72 KD TYPE IV COLLAGENASE PRECURSOR (72 KD GELATINASE) (MATRIX
METALLOPROTEINASE-2) (MMP-2) (GELATINASE A)
pir||A42496 gelatinase A (EC 3.4.24.24) precursor - mouse
gb|AAA39338.1| (M84324) type IV collagenase [Mus musculus]
Length = 662
Score = 1316 bits (3368), Expect = 0.0
Identities = 609/662 (91%), Positives = 620/662 (92%), Gaps = 2/662 (0%)
Query: 1 MEALMARGALTGPXXXXXXXXXXXXXXXXXPSPIIKFPGDVAPKTDKELAVQYLNTFYGC 60
MEA +A GAL GP PSPIIKFPGDVAPKTDKELAVQYLNTFYGC
Sbjct: 1 MEARVAWGALAGPLRVLCVLCCLLGRAIAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGC 60
Query: 61 PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD 120
PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD
Sbjct: 61 PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD 120
Query: 121 KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD 180
KNQITYRIIGYTPDLDPETVDDAFARA +VWSDVTPLRFSRIHDGEADIMINFGRWEHGD
Sbjct: 121 KNQITYRIIGYTPDLDPETVDDAFARALKVWSDVTPLRFSRIHDGEADIMINFGRWEHGD 180
Query: 181 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN 240
GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
Sbjct: 181 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN 240
Query: 241 GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT 300
G+EY+SCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA+GQPCKFPFRFQGT
Sbjct: 241 GREYSSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNADGQPCKFPFRFQGT 300
Query: 301 SYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY 360
SY+SCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY
Sbjct: 301 SYNSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY 360
Query: 361 ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL 420
ESCTSAGR+DGK+WCATT NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
Sbjct: 361 ESCTSAGRNDGKVWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL 420
Query: 421 MAPIYTYTKNFRLSQDDIKGIQELYGASPDIDXXXXX--XXXXXXXXXEICKQDIVFDGI 478
MAPIYTYTKNFRLS DDIKGIQELYG SPD D EICKQDIVFDGI
Sbjct: 421 MAPIYTYTKNFRLSHDDIKGIQELYGPSPDADTDTGTGPTPTLGPVTPEICKQDIVFDGI 480
Query: 479 AQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGN 538
AQIRGEIFFFKDRFIWRTVTPRDKP GPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGN
Sbjct: 481 AQIRGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGN 540
Query: 539 EYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKM 598
EYW+YSASTLERGYPKPLTSLGLPPDVQ+VDAAFNWSKNKKTYIFAGDKFWRYNEVKKKM
Sbjct: 541 EYWVYSASTLERGYPKPLTSLGLPPDVQQVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKM 600
Query: 599 DPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWL 658
DPGFPKLIAD+WNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWL
Sbjct: 601 DPGFPKLIADSWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWL 660
Query: 659 GC 660
GC
Sbjct: 661 GC 662
>sp|P33436|COG2_RAT 72 KD TYPE IV COLLAGENASE PRECURSOR (72 KD GELATINASE) (MATRIX
METALLOPROTEINASE-2) (MMP-2) (GELATINASE A)
pir||S34780 gelatinase A (EC 3.4.24.24) precursor - rat
emb|CAA50583.1| (X71466) type IV collagenase [Rattus norvegicus]
Length = 662
Score = 1313 bits (3361), Expect = 0.0
Identities = 607/662 (91%), Positives = 618/662 (92%), Gaps = 2/662 (0%)
Query: 1 MEALMARGALTGPXXXXXXXXXXXXXXXXXPSPIIKFPGDVAPKTDKELAVQYLNTFYGC 60
MEA + G L GP PSPIIKFPGDVAPKTDKELAVQYLNTFYGC
Sbjct: 1 MEARLVWGVLVGPLRVLCVLCCLLGHAIAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGC 60
Query: 61 PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD 120
PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD
Sbjct: 61 PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD 120
Query: 121 KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD 180
KNQITYRIIGYTPDLDPETVDDAFARA +VWSDVTPLRFSRIHDGEADIMINFGRWEHGD
Sbjct: 121 KNQITYRIIGYTPDLDPETVDDAFARALKVWSDVTPLRFSRIHDGEADIMINFGRWEHGD 180
Query: 181 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN 240
GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
Sbjct: 181 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN 240
Query: 241 GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT 300
G+EY+SCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA+GQPCKFPFRFQGT
Sbjct: 241 GREYSSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNADGQPCKFPFRFQGT 300
Query: 301 SYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY 360
SY+SCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY
Sbjct: 301 SYNSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY 360
Query: 361 ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL 420
ESCTSAGR+DGK+WCATT NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
Sbjct: 361 ESCTSAGRNDGKVWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL 420
Query: 421 MAPIYTYTKNFRLSQDDIKGIQELYGASPDIDXXXXX--XXXXXXXXXEICKQDIVFDGI 478
MAPIYTYTKNFRLS DDIKGIQELYG SPD D EICKQDIVFDGI
Sbjct: 421 MAPIYTYTKNFRLSHDDIKGIQELYGPSPDADTDTGTGPTPTLGPVTPEICKQDIVFDGI 480
Query: 479 AQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGN 538
AQIRGEIFFFKDRFIWRTVTPRDKP GPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGN
Sbjct: 481 AQIRGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGN 540
Query: 539 EYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKM 598
EYW+YSASTLERGYPKPLTSLGLPPDVQ+VDAAFNWSKNKKTYIFAGDKFWRYNEVKKKM
Sbjct: 541 EYWVYSASTLERGYPKPLTSLGLPPDVQQVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKM 600
Query: 599 DPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWL 658
DPGFPKLIAD+WNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWL
Sbjct: 601 DPGFPKLIADSWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWL 660
Query: 659 GC 660
GC
Sbjct: 661 GC 662
>gb|AAB41692.1| (U65656) gelatinase A [Rattus norvegicus]
Length = 662
Score = 1310 bits (3354), Expect = 0.0
Identities = 605/662 (91%), Positives = 617/662 (92%), Gaps = 2/662 (0%)
Query: 1 MEALMARGALTGPXXXXXXXXXXXXXXXXXPSPIIKFPGDVAPKTDKELAVQYLNTFYGC 60
MEA + G L GP PSPIIKFPGDV+PKTDKELAVQYLNTFYGC
Sbjct: 1 MEARLVWGVLVGPLRVLCVLCCLLGHAIAAPSPIIKFPGDVSPKTDKELAVQYLNTFYGC 60
Query: 61 PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD 120
PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD
Sbjct: 61 PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD 120
Query: 121 KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD 180
KNQITYRIIGYTPDLDPETVDDAFARA +VWSDVTPLRFSRIHDGEADIMINFGRWEHGD
Sbjct: 121 KNQITYRIIGYTPDLDPETVDDAFARALKVWSDVTPLRFSRIHDGEADIMINFGRWEHGD 180
Query: 181 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN 240
GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
Sbjct: 181 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN 240
Query: 241 GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT 300
G+EY+SCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGN +GQPCKFPFRFQGT
Sbjct: 241 GREYSSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNGDGQPCKFPFRFQGT 300
Query: 301 SYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY 360
SY+SCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY
Sbjct: 301 SYNSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY 360
Query: 361 ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL 420
ESCTSAGRSDGK+WCATT NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
Sbjct: 361 ESCTSAGRSDGKVWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL 420
Query: 421 MAPIYTYTKNFRLSQDDIKGIQELYGASPDIDXXXXX--XXXXXXXXXEICKQDIVFDGI 478
MAPIYTYTKNFRLS DDIKGIQELYG SPD D EICKQDIVFDGI
Sbjct: 421 MAPIYTYTKNFRLSNDDIKGIQELYGPSPDADTDTGTGPTPTLGPVTPEICKQDIVFDGI 480
Query: 479 AQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGN 538
AQIRGEIFFFKDRFIWRTVTPRDKP GPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGN
Sbjct: 481 AQIRGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGN 540
Query: 539 EYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKM 598
EYW+YSASTLERGYPKPLTSLGLPPDVQ+VDAAFNWSKNKKTYIF+GDKFWRYNEVKKKM
Sbjct: 541 EYWVYSASTLERGYPKPLTSLGLPPDVQQVDAAFNWSKNKKTYIFSGDKFWRYNEVKKKM 600
Query: 599 DPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWL 658
DPGFPKLIAD+WNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWL
Sbjct: 601 DPGFPKLIADSWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWL 660
Query: 659 GC 660
GC
Sbjct: 661 GC 662
>gb|AAF67517.1|AF177217_1 (AF177217) matrix metalloproteinase-2 [Canis familiaris]
Length = 632
Score = 1307 bits (3346), Expect = 0.0
Identities = 598/630 (94%), Positives = 610/630 (95%)
Query: 31 PSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLD 90
PSPIIKFPGDVAPKTDKELAVQYLNT+YGCPKE CNLFVLKDTLKKMQKFFGLPQTG+LD
Sbjct: 3 PSPIIKFPGDVAPKTDKELAVQYLNTYYGCPKERCNLFVLKDTLKKMQKFFGLPQTGELD 62
Query: 91 QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV 150
Q+TIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV
Sbjct: 63 QSTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV 122
Query: 151 WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD 210
WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPG GVGGDSHFDDD
Sbjct: 123 WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGPGVGGDSHFDDD 182
Query: 211 ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK 270
ELWTLGEGQVVRVKYGNADGEYCKFPFLFNG+EY SCTDTGRSDGFLWCSTTYNFEKDGK
Sbjct: 183 ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGREYTSCTDTGRSDGFLWCSTTYNFEKDGK 242
Query: 271 YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG 330
YGFCPHEALFTMGGNA+GQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG
Sbjct: 243 YGFCPHEALFTMGGNADGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG 302
Query: 331 FCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFC 390
FCPETAMST+GGNSEGAPCVFPFTFLGNK+ESCTSAGRSDGK+WCATTANYDDDRKWGFC
Sbjct: 303 FCPETAMSTIGGNSEGAPCVFPFTFLGNKHESCTSAGRSDGKVWCATTANYDDDRKWGFC 362
Query: 391 PDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD 450
PDQGYSLFLVAAHEFGHAMGLEHS+DPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD
Sbjct: 363 PDQGYSLFLVAAHEFGHAMGLEHSEDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD 422
Query: 451 IDXXXXXXXXXXXXXXEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVA 510
EICKQDIVFDGI+QIRGEIFFFKDRFIWRTVTPR+KPMGPLLVA
Sbjct: 423 AGTGTGPTPTLGPVTPEICKQDIVFDGISQIRGEIFFFKDRFIWRTVTPRNKPMGPLLVA 482
Query: 511 TFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDA 570
TFWPELPEKIDAVYEAPQEEKAVFFAGNEYW+YSASTLERGYPKPLTSLGLPPDVQRVDA
Sbjct: 483 TFWPELPEKIDAVYEAPQEEKAVFFAGNEYWVYSASTLERGYPKPLTSLGLPPDVQRVDA 542
Query: 571 AFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSY 630
AFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQG GHSY
Sbjct: 543 AFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGSGHSY 602
Query: 631 FFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
FFKGAYYLKLENQSLKSVKFGSIKSDWLGC
Sbjct: 603 FFKGAYYLKLENQSLKSVKFGSIKSDWLGC 632
>sp|P50757|COG2_RABIT 72 KD TYPE IV COLLAGENASE PRECURSOR (72 KD GELATINASE) (MATRIX
METALLOPROTEINASE-2) (MMP-2) (GELATINASE A)
pir||S70365 gelatinase A (EC 3.4.24.24) precursor - rabbit
dbj|BAA09796.1| (D63579) matrix metalloproteinase-2 [Oryctolagus cuniculus]
Length = 662
Score = 1306 bits (3343), Expect = 0.0
Identities = 605/662 (91%), Positives = 617/662 (92%), Gaps = 2/662 (0%)
Query: 1 MEALMARGALTGPXXXXXXXXXXXXXXXXXPSPIIKFPGDVAPKTDKELAVQYLNTFYGC 60
MEAL ARGAL G PSP+IKFPGDVAPKTDKELAVQYLNTFYGC
Sbjct: 1 MEALGARGALAGFLRALCVLGCLLGRATAPPSPVIKFPGDVAPKTDKELAVQYLNTFYGC 60
Query: 61 PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD 120
PK+SCNLFVLKDTLKKMQKFFGLPQTG+LDQ+TIETMRKPRCGNPDVANYNFFPRKPKWD
Sbjct: 61 PKDSCNLFVLKDTLKKMQKFFGLPQTGELDQSTIETMRKPRCGNPDVANYNFFPRKPKWD 120
Query: 121 KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD 180
KNQITYRIIGYTPDLDPETVDDAFARAFQVWS+VTPLRFSRIHDGEADIMINFGRWEHGD
Sbjct: 121 KNQITYRIIGYTPDLDPETVDDAFARAFQVWSNVTPLRFSRIHDGEADIMINFGRWEHGD 180
Query: 181 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN 240
GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
Sbjct: 181 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN 240
Query: 241 GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT 300
GKEY SCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA+GQPCKFPFRFQGT
Sbjct: 241 GKEYTSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNADGQPCKFPFRFQGT 300
Query: 301 SYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY 360
SY SCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMST+GGNSEGAPCVFPFTFLGNKY
Sbjct: 301 SYSSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTIGGNSEGAPCVFPFTFLGNKY 360
Query: 361 ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL 420
ESCTSAGRSDGKMWCAT+ NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
Sbjct: 361 ESCTSAGRSDGKMWCATSTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL 420
Query: 421 MAPIYTYTKNFRLSQDDIKGIQELYGASPD--IDXXXXXXXXXXXXXXEICKQDIVFDGI 478
MAPIYTYTKNFRLSQDDIKGIQELYGASPD D EIC QDIVFDGI
Sbjct: 421 MAPIYTYTKNFRLSQDDIKGIQELYGASPDAGTDAGTGPTPTLGPVTPEICTQDIVFDGI 480
Query: 479 AQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGN 538
AQIRGEIFFFKDRFIWRTVTP DKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGN
Sbjct: 481 AQIRGEIFFFKDRFIWRTVTPGDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGN 540
Query: 539 EYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKM 598
EYW+YSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKM
Sbjct: 541 EYWVYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKM 600
Query: 599 DPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWL 658
DPGFP+LIADAWNAIPD+LDAVVDLQG GHSYFFKG YYLKLENQSLKSVK GSIK+DWL
Sbjct: 601 DPGFPRLIADAWNAIPDHLDAVVDLQGSGHSYFFKGTYYLKLENQSLKSVKVGSIKTDWL 660
Query: 659 GC 660
GC
Sbjct: 661 GC 662
>gb|AAG28169.1|AF290428_1 (AF290428) matrix metalloprotease 2 [Bos taurus]
Length = 661
Score = 1299 bits (3325), Expect = 0.0
Identities = 599/659 (90%), Positives = 615/659 (92%)
Query: 2 EALMARGALTGPXXXXXXXXXXXXXXXXXPSPIIKFPGDVAPKTDKELAVQYLNTFYGCP 61
EA ++RGAL PSPIIKFPGDVAPKTDKELAVQYLNTFYGCP
Sbjct: 3 EARVSRGALAALLRALCALGCLLGRAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCP 62
Query: 62 KESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDK 121
KESCNLFVLKDTLKKMQKFFGLPQTG+LDQ+TIETMRKPRCGNPDVANYNFFPRKPKWDK
Sbjct: 63 KESCNLFVLKDTLKKMQKFFGLPQTGELDQSTIETMRKPRCGNPDVANYNFFPRKPKWDK 122
Query: 122 NQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDG 181
NQITYRIIGYTPDLDP+TVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDG
Sbjct: 123 NQITYRIIGYTPDLDPQTVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDG 182
Query: 182 YPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNG 241
YPFDGKDGLLAHAFAPG GVGGDSHFDDDEL TLGEGQVVRVKYGNADGEYCKFPF FNG
Sbjct: 183 YPFDGKDGLLAHAFAPGPGVGGDSHFDDDELRTLGEGQVVRVKYGNADGEYCKFPFRFNG 242
Query: 242 KEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTS 301
KEY SCTDTGRSDGFLWCSTTYNF+KDGKYGFCPHEALFTMGGNA+GQPCKFPFRFQGTS
Sbjct: 243 KEYTSCTDTGRSDGFLWCSTTYNFDKDGKYGFCPHEALFTMGGNADGQPCKFPFRFQGTS 302
Query: 302 YDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYE 361
YDSCTTEGRTDGYRWCGTTEDYDRDK+YGFCPETAMSTVGGNSEGAPCV PFTFLGNK+E
Sbjct: 303 YDSCTTEGRTDGYRWCGTTEDYDRDKEYGFCPETAMSTVGGNSEGAPCVLPFTFLGNKHE 362
Query: 362 SCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALM 421
SCTSAGRSDGK+WCATT+NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALM
Sbjct: 363 SCTSAGRSDGKLWCATTSNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALM 422
Query: 422 APIYTYTKNFRLSQDDIKGIQELYGASPDIDXXXXXXXXXXXXXXEICKQDIVFDGIAQI 481
APIYTYTKNFRLS DDI+GIQELYGASPDID E+CKQDIVFDGI+QI
Sbjct: 423 APIYTYTKNFRLSHDDIQGIQELYGASPDIDTGTGPTPTLGPVTPELCKQDIVFDGISQI 482
Query: 482 RGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYW 541
RGEIFFFKDRFIWRTVTPRDKP GPLLVATFWPELPEKIDAVYE PQEEKAVFFAGNEYW
Sbjct: 483 RGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEDPQEEKAVFFAGNEYW 542
Query: 542 IYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPG 601
+YSASTLERGYPKPLTSLGLPP VQ+VDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPG
Sbjct: 543 VYSASTLERGYPKPLTSLGLPPGVQKVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPG 602
Query: 602 FPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
FPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
Sbjct: 603 FPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 661
>sp|Q90611|COG2_CHICK 72 KD TYPE IV COLLAGENASE PRECURSOR (72 KD GELATINASE) (MATRIX
METALLOPROTEINASE-2) (MMP-2) (GELATINASE A)
pir||S46492 gelatinase A (EC 3.4.24.24) precursor - chicken
gb|AAA19596.1| (U07775) prepro-72kDa matrix metalloproteinase [Gallus gallus]
Length = 663
Score = 1181 bits (3021), Expect = 0.0
Identities = 528/636 (83%), Positives = 578/636 (90%), Gaps = 6/636 (0%)
Query: 31 PSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLD 90
PSPIIKFPGD PKTDKELAVQYLN +YGCPK++CNLFVLKDTLKKMQKFFGLP+TGDLD
Sbjct: 28 PSPIIKFPGDSTPKTDKELAVQYLNKYYGCPKDNCNLFVLKDTLKKMQKFFGLPETGDLD 87
Query: 91 QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV 150
QNTIETM+KPRCGNPDVANYNFFPRKPKW+KN ITYRIIGYTPDLDPETVDDAFARAF+V
Sbjct: 88 QNTIETMKKPRCGNPDVANYNFFPRKPKWEKNHITYRIIGYTPDLDPETVDDAFARAFKV 147
Query: 151 WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD 210
WSDVTPLRF+RI+DGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPG G+GGDSHFDDD
Sbjct: 148 WSDVTPLRFNRINDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGPGIGGDSHFDDD 207
Query: 211 ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK 270
ELWTLGEGQVVRVKYGNADGEYCKFPF FNGKEYNSCTD GR+DGFLWCSTT +F+ DGK
Sbjct: 208 ELWTLGEGQVVRVKYGNADGEYCKFPFWFNGKEYNSCTDAGRNDGFLWCSTTKDFDADGK 267
Query: 271 YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG 330
YGFCPHE+LFTMGGN +GQPCKFPF+FQG SYD CTTEGRTDGYRWCGTTEDYDRDKKYG
Sbjct: 268 YGFCPHESLFTMGGNGDGQPCKFPFKFQGQSYDQCTTEGRTDGYRWCGTTEDYDRDKKYG 327
Query: 331 FCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFC 390
FCPETAMSTVGGNSEGAPCVFPF FLGNKY+SCTSAGR+DGK+WCA+T++YDDDRKWGFC
Sbjct: 328 FCPETAMSTVGGNSEGAPCVFPFIFLGNKYDSCTSAGRNDGKLWCASTSSYDDDRKWGFC 387
Query: 391 PDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD 450
PDQGYSLFLVAAHEFGHAMGLEHS+DPGALMAPIYTYTKNFRLSQDDIKGIQELY SPD
Sbjct: 388 PDQGYSLFLVAAHEFGHAMGLEHSEDPGALMAPIYTYTKNFRLSQDDIKGIQELYEVSPD 447
Query: 451 ID------XXXXXXXXXXXXXXEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPM 504
++ E+CK DIVFDG+AQIRGEIFFFKDRF+WRTV PR KP
Sbjct: 448 VEPGPGPGPGPGPRPTLGPVTPELCKHDIVFDGVAQIRGEIFFFKDRFMWRTVNPRGKPT 507
Query: 505 GPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPD 564
GPLLVATFWP+LPEKIDAVYE+PQ+EKAVFFAGNEYW+Y+AS L+RGYPK LTSLGLPPD
Sbjct: 508 GPLLVATFWPDLPEKIDAVYESPQDEKAVFFAGNEYWVYTASNLDRGYPKKLTSLGLPPD 567
Query: 565 VQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQ 624
VQR+DAAFNW +NKKTYIF+GD++W+YNE KKKM+ PK IAD+WN +PDNLDAV+ L
Sbjct: 568 VQRIDAAFNWGRNKKTYIFSGDRYWKYNEEKKKMELATPKFIADSWNGVPDNLDAVLGLT 627
Query: 625 GGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
G++YFFK YYL++E++SLK VK G I SDWLGC
Sbjct: 628 DSGYTYFFKDQYYLQMEDKSLKIVKIGKISSDWLGC 663
>dbj|BAA85769.2| (AB033754) gelatinase A [Oryzias latipes]
Length = 657
Score = 1042 bits (2664), Expect = 0.0
Identities = 465/630 (73%), Positives = 530/630 (83%), Gaps = 3/630 (0%)
Query: 31 PSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLD 90
PSPII+FPGD PKTDKE+A+ YLN FYGCP++SCNL VLKDTLK MQKFF LP+TG++D
Sbjct: 31 PSPIIRFPGDDTPKTDKEVALDYLNKFYGCPQDSCNLMVLKDTLKTMQKFFTLPETGEID 90
Query: 91 QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV 150
T+ M+KPRCG PDVANYNFF KPKW K ITYRI+GY+PDLD E ++DAF RAF+V
Sbjct: 91 AQTVAIMKKPRCGVPDVANYNFFHNKPKWQKKDITYRILGYSPDLDEEVINDAFYRAFKV 150
Query: 151 WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD 210
WSDVTPL F+RI DGEADIMINFGR EHGDGYPFDGKDGLLAHAFAPG G+GGDSHFDDD
Sbjct: 151 WSDVTPLSFTRIMDGEADIMINFGRNEHGDGYPFDGKDGLLAHAFAPGGGIGGDSHFDDD 210
Query: 211 ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK 270
E WTLGEGQVV+ K+GNADGE+CKFPFLF G EY SCT GR DGFLWCSTTYNF++DGK
Sbjct: 211 EQWTLGEGQVVKAKFGNADGEFCKFPFLFMGTEYKSCTAQGRDDGFLWCSTTYNFDEDGK 270
Query: 271 YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG 330
YGFCPHE LFT+GGN +G PCKFPF FQG YDSCTTEGR DGYRWC TTEDYDRD YG
Sbjct: 271 YGFCPHELLFTLGGNGDGAPCKFPFTFQGKQYDSCTTEGRDDGYRWCATTEDYDRDTSYG 330
Query: 331 FCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFC 390
FCPETAMSTVGGN EG+PCVFPFTFLG+ YESCT++GRSDGKMWCATT +YDDDRKWGFC
Sbjct: 331 FCPETAMSTVGGNGEGSPCVFPFTFLGDTYESCTTSGRSDGKMWCATTKSYDDDRKWGFC 390
Query: 391 PDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD 450
PDQGYSLFLVAAHEFGHA+GLEHSQDPGALMAP+YT+TK+FRL QDDI+GIQELYG D
Sbjct: 391 PDQGYSLFLVAAHEFGHALGLEHSQDPGALMAPVYTFTKDFRLPQDDIQGIQELYGVPTD 450
Query: 451 IDXXXXXXXXXXXXXXEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVA 510
+ICK+ IVFD +AQIRGE FFFKDRF++R+V R KP GPLLVA
Sbjct: 451 ---KPLPPTQGPVTPMDICKESIVFDAVAQIRGETFFFKDRFLFRSVNFRSKPKGPLLVA 507
Query: 511 TFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDA 570
T+WP+LP KIDA YE P EEK VFFAGN++W+Y A L+ GYP+ L++L LP DVQR+DA
Sbjct: 508 TYWPDLPAKIDAAYENPAEEKTVFFAGNQFWVYRADELQSGYPRRLSNLDLPDDVQRIDA 567
Query: 571 AFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSY 630
AFN+ +N+KTY+F+GDKFWRY+E +K MDPGFPKLIAD+WN IPD+LD+ L G +SY
Sbjct: 568 AFNFRRNRKTYLFSGDKFWRYDEDRKTMDPGFPKLIADSWNGIPDDLDSAFSLNGIDYSY 627
Query: 631 FFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
FFKG +Y KLE+ +LK VK G IK+DWLGC
Sbjct: 628 FFKGNHYFKLEDNTLKIVKLGEIKTDWLGC 657
>dbj|BAA78479.1| (AB021698) matrix metalloproteinase-2 [Oncorhynchus mykiss]
Length = 655
Score = 1039 bits (2658), Expect = 0.0
Identities = 461/630 (73%), Positives = 535/630 (84%), Gaps = 3/630 (0%)
Query: 31 PSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLD 90
PSPIIKFPGD +PKTDKE+A+ YLN FYGCP++ CNL VLKDTLKKMQKFF L +TG++D
Sbjct: 28 PSPIIKFPGDDSPKTDKEVALHYLNKFYGCPQDRCNLMVLKDTLKKMQKFFSLQETGEID 87
Query: 91 QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV 150
T+E M+KPRCG PDVA YNFF RKPKW +N ITYRI+G++PDLD ET+DDAF RAF+V
Sbjct: 88 PKTVEIMKKPRCGVPDVAQYNFFHRKPKWQQNAITYRILGHSPDLDEETIDDAFLRAFKV 147
Query: 151 WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD 210
WSDVTPL+F+R+ DGEADIMINFGR EHGDGYPFDGKDGLLAHAFAPG G GGDSHFDDD
Sbjct: 148 WSDVTPLKFTRLMDGEADIMINFGRNEHGDGYPFDGKDGLLAHAFAPGPGTGGDSHFDDD 207
Query: 211 ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK 270
E WTLGEGQVV+VK+GNA+GE+CKFPF+F GKEYNSCT+ GR DGFLWCSTTYNF+ DGK
Sbjct: 208 EQWTLGEGQVVKVKFGNAEGEFCKFPFMFMGKEYNSCTNQGRDDGFLWCSTTYNFDDDGK 267
Query: 271 YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG 330
YGFCPHE LFT+GGNA+G PCKFPF FQG +YD CTT+GR DGYRWC TTE+YD DK YG
Sbjct: 268 YGFCPHELLFTLGGNADGAPCKFPFTFQGENYDGCTTQGRDDGYRWCATTENYDNDKSYG 327
Query: 331 FCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFC 390
FCPETAMSTVGGNSEG+PCVFPFTFLG+ Y+SCT++GRSDGKMWCA+T +YDDDRKWGFC
Sbjct: 328 FCPETAMSTVGGNSEGSPCVFPFTFLGDTYDSCTASGRSDGKMWCASTKSYDDDRKWGFC 387
Query: 391 PDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD 450
PDQGYSLFLVAAHEFGHA+GLEHSQDPGALMAP+YT+TKNFRLS DDIKGIQELYGA D
Sbjct: 388 PDQGYSLFLVAAHEFGHALGLEHSQDPGALMAPMYTFTKNFRLSNDDIKGIQELYGAGTD 447
Query: 451 IDXXXXXXXXXXXXXXEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVA 510
+IC + +VFD +AQIRGE FFFKDRFI+R+ R KP GP+LVA
Sbjct: 448 ---KPVPPTQGPVTPMDICNEPVVFDAVAQIRGETFFFKDRFIFRSTNFRGKPSGPMLVA 504
Query: 511 TFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDA 570
T+WPELP IDA YE P EEK VFFAGNE WI++A +E+GYPK ++S+GLP D++ +DA
Sbjct: 505 TYWPELPVTIDAAYENPLEEKTVFFAGNEMWIFNADQIEKGYPKRISSIGLPTDLKGIDA 564
Query: 571 AFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSY 630
AF++ K++KTY+FAGD+FWRYNE KKKMD GFPKLIAD+WN IPD +D+ L G ++Y
Sbjct: 565 AFSFGKSQKTYLFAGDQFWRYNEAKKKMDLGFPKLIADSWNGIPDGIDSAFSLNGIDYTY 624
Query: 631 FFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
FFKGA+Y K+++ SLK VK G I DWLGC
Sbjct: 625 FFKGAHYFKMDDSSLKIVKLGEITKDWLGC 654
>emb|CAB46656.1| (AJ243311) matrix metalloproteinase-2 [Equus caballus]
Length = 385
Score = 782 bits (1997), Expect = 0.0
Identities = 355/385 (92%), Positives = 362/385 (93%), Gaps = 2/385 (0%)
Query: 109 NYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEAD 168
NYNFFPRKPKW+K QITYRIIGYTPDLDPETVDDAFARAF+VWSDVTPLRFSRIHDGEAD
Sbjct: 1 NYNFFPRKPKWEKTQITYRIIGYTPDLDPETVDDAFARAFRVWSDVTPLRFSRIHDGEAD 60
Query: 169 IMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNA 228
IMINFGRWEHGDGYPFDGKDGLLAHAFAPG GVGGDSHFDDDELWTLGEGQVVRVKYGNA
Sbjct: 61 IMINFGRWEHGDGYPFDGKDGLLAHAFAPGPGVGGDSHFDDDELWTLGEGQVVRVKYGNA 120
Query: 229 DGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEG 288
DGEYCKFPFLFNGKEY SCTDTGRSDGFLWCSTTYNF+KDGKYGFCPHEALFTMGGNA+G
Sbjct: 121 DGEYCKFPFLFNGKEYTSCTDTGRSDGFLWCSTTYNFDKDGKYGFCPHEALFTMGGNADG 180
Query: 289 QPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAP 348
QPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAP
Sbjct: 181 QPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAP 240
Query: 349 CVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHA 408
CVFPFTFLGNK+E CTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHA
Sbjct: 241 CVFPFTFLGNKHEGCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHA 300
Query: 409 MGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD--IDXXXXXXXXXXXXXX 466
MGLEHSQDPGALMAPIYTYTK+FRLS DDIKGIQELYG SPD D
Sbjct: 301 MGLEHSQDPGALMAPIYTYTKHFRLSHDDIKGIQELYGGSPDTGTDAGTGPTPTLGPVTP 360
Query: 467 EICKQDIVFDGIAQIRGEIFFFKDR 491
EICKQDIVFDGI+QIRGEIFFFKDR
Sbjct: 361 EICKQDIVFDGISQIRGEIFFFKDR 385
>dbj|BAA85770.1| (AB033755) gelatinase B [Oryzias latipes]
Length = 690
Score = 671 bits (1712), Expect = 0.0
Identities = 330/665 (49%), Positives = 424/665 (63%), Gaps = 43/665 (6%)
Query: 32 SPIIKFPGDVAPK-TDKELAVQYLNTF-YGCPKESCNLFVLKDT---LKKMQKFFGLPQT 86
S + FPGDV +D +LA YL F Y + L T LK+MQ+ GL +T
Sbjct: 26 SVFVTFPGDVIKNMSDTDLAESYLRKFGYMDTFQRSGFQSLASTSKALKRMQRQLGLDET 85
Query: 87 GDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFAR 146
G LD T+E M++PRCG PDVANY F KWD +TYRI+ Y+PDLD DDAFAR
Sbjct: 86 GQLDMQTLEAMKQPRCGVPDVANYKTFDGDLKWDHGDVTYRILNYSPDLDSSVTDDAFAR 145
Query: 147 AFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSH 206
AF+VWSDVTPL F+R+ DG ADIMI+FG+ +HGD YPFDGKDGLLAHA+ PG G+ GD+H
Sbjct: 146 AFKVWSDVTPLTFTRLFDGTADIMISFGKKDHGDLYPFDGKDGLLAHAYPPGEGIQGDAH 205
Query: 207 FDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFE 266
FDDDE WTLG+G VV+ YGNADG C FPF+F GK Y SCT GR+D WCSTT +++
Sbjct: 206 FDDDEFWTLGKGPVVKTYYGNADGAMCHFPFVFGGKTYTSCTSEGRADKLPWCSTTDDYD 265
Query: 267 KDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRD 326
+DGKYGFCP E L+T+GGN++G C FPF F G YDSCTTEGR DGYRWC TT +YD+D
Sbjct: 266 RDGKYGFCPSELLYTIGGNSDGAKCVFPFVFLGDEYDSCTTEGRRDGYRWCATTSNYDQD 325
Query: 327 KKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRK 386
KKYGFCP T +T+GGN+EG PC FPF FLG +Y+SCTS GR DGK+WC TTA+YDDD+K
Sbjct: 326 KKYGFCPNTDTTTIGGNAEGEPCHFPFEFLGKEYDSCTSEGRGDGKLWCGTTASYDDDKK 385
Query: 387 WGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYG 446
WGFCPDQGYSLFLVAAHEFGHA+GL+HS ALM P+Y+Y ++F L +DDI+GIQ LYG
Sbjct: 386 WGFCPDQGYSLFLVAAHEFGHALGLDHSNIRDALMYPMYSYVEDFSLHEDDIEGIQYLYG 445
Query: 447 ------------------ASPDIDXX------------XXXXXXXXXXXXEICKQDIVFD 476
A+PD D + CK FD
Sbjct: 446 SKTDPKPTVPQPKPPTTTATPDPDVTDSTDEPEPTNRPATTTLNPLDPTKDACKV-TKFD 504
Query: 477 GIAQIRGEIFFFKDRFIWRTVTPRDKPM-GPLLVATFWPELPEKIDAVYEAPQEEKAVFF 535
I I G+++FFKD WR D + P+L++ WP LP ID+ +E +K FF
Sbjct: 505 TITVIGGDLYFFKDGHFWRKSRKGDAALESPMLISERWPALPAVIDSAFEDILTKKLYFF 564
Query: 536 AGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVK 595
+G ++W+Y+ + P+ + LGLP VQ+V+ A K+ K +F+G+ FWR +
Sbjct: 565 SGTKFWVYTGKNVLG--PRSIEKLGLPDSVQKVEGALQKGKD-KVLLFSGENFWRLDVKT 621
Query: 596 KKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKS 655
+K+D G+PK I + +P +DA G ++F + +Y ++ N + + G +K
Sbjct: 622 QKIDKGYPKYIDVVFGGVP--IDAHDVFLYEGRTFFCRDQFYWRM-NSRRQVDRVGYVKY 678
Query: 656 DWLGC 660
D L C
Sbjct: 679 DLLKC 683
>gb|AAD41624.1|AF072455_1 (AF072455) gelatinase B [Xenopus laevis]
Length = 671
Score = 658 bits (1680), Expect = 0.0
Identities = 321/650 (49%), Positives = 423/650 (64%), Gaps = 28/650 (4%)
Query: 32 SPI-IKFPGDV-APKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDL 89
SP+ I FPGD+ + TD ELA YL F +E + L++ L MQ+ GL +TG L
Sbjct: 26 SPLTILFPGDIQSGTTDMELAESYLLQFGYLIQEQGSNATLQNALTIMQQKLGLKETGVL 85
Query: 90 DQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQ 149
D T+E M++PRCG PD+ +N F KWD N ITYRI+ Y+PDLDPE +DDAFARAF+
Sbjct: 86 DAETLEAMKRPRCGVPDIGQFNTFEGDLKWDHNDITYRILNYSPDLDPEVIDDAFARAFK 145
Query: 150 VWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDD 209
VWSDVTPL F+RI+ GE DI I FG +HGD YPFD KDGLLAHA+ PG GV GD+HFDD
Sbjct: 146 VWSDVTPLSFTRIYSGEPDINILFGTEDHGDPYPFDRKDGLLAHAYPPGPGVQGDAHFDD 205
Query: 210 DELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDG 269
DE WTLG G VV+ ++GNA+G C+FPF F+G+ +++CT GRSDG WCSTT N+++D
Sbjct: 206 DEFWTLGTGTVVKTRFGNAEGALCRFPFTFDGQSFSTCTTAGRSDGLPWCSTTPNYDQDK 265
Query: 270 KYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKY 329
KYGFCP E L+T GGN+ GQPC PF F G SY+ CT EGR DGYRWC TT ++D+DKKY
Sbjct: 266 KYGFCPSEMLYTYGGNSNGQPCVLPFIFDGVSYNGCTKEGRQDGYRWCSTTANFDQDKKY 325
Query: 330 GFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGF 389
GFCP S +GGNS+G PCVFPFTFLG + SCT+ GR D K+WCATT+NYD D KWGF
Sbjct: 326 GFCPNRDTSVIGGNSQGEPCVFPFTFLGKIHNSCTTDGRDDRKLWCATTSNYDLDSKWGF 385
Query: 390 CPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELY---- 445
CPDQGYSLFLVAAHEFGHA+GL+HS ALM P+Y+Y K+F+L QDD++GIQ LY
Sbjct: 386 CPDQGYSLFLVAAHEFGHALGLDHSDVQDALMYPMYSYVKDFQLHQDDVRGIQFLYGTGS 445
Query: 446 GASPDIDXXXXXXXXXXXXXXEICKQDI-------------VFDGIAQIRGEIFFFKDRF 492
GA P+ + + + +FD IA ++G + FFKD
Sbjct: 446 GAPPNPNPPKPTKKPLATKRPRTTTRPVPPVNPAQDACNVEMFDAIADLQGALHFFKDGL 505
Query: 493 IWRTVTPRDK--PMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLER 550
W T+TPR K P PL ++ WP LP KID ++ P + FF+G+++W Y+ ++
Sbjct: 506 YW-TLTPRSKNSPQSPLRISDTWPALPSKIDTAFQDPTSKSIFFFSGSKFWQYTGTSAIG 564
Query: 551 GYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAW 610
P+ + LGL DV+ + +F N K +F G+++WR N +D G+P+ AD +
Sbjct: 565 --PRSIEKLGLSKDVEAIMGSFA-RDNGKALLFNGEQYWRLNLKTLTIDNGYPRQTADNY 621
Query: 611 NAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
+P + V Q G+ YF + Y+ ++ ++ + + G + D L C
Sbjct: 622 PGVPGDSHDVFLYQ--GNYYFCQDQYFWRVTSRKQQDM-VGYVSYDLLRC 668
>dbj|BAA11523.1| (D82052) gelatinase-b [Cynops pyrrhogaster]
Length = 679
Score = 650 bits (1659), Expect = 0.0
Identities = 318/658 (48%), Positives = 419/658 (63%), Gaps = 35/658 (5%)
Query: 31 PSPIIKFPGD-VAPKTDKELAVQYLNTFYGCPKE--SCNLFVLKDTLKKMQKFFGLPQTG 87
P + FPG+ V+ +D ELA YL F K S L L +MQK GL +TG
Sbjct: 26 PQVRVTFPGELVSGISDDELAESYLERFGYISKRARSSTHVSLSKALLQMQKKLGLNETG 85
Query: 88 DLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARA 147
+LDQ+T+E M+ PRCG PDV N+ F KWD N IT+R++ Y+PDLD + ++DAF RA
Sbjct: 86 ELDQSTLEAMKTPRCGVPDVGNFQTFDGDLKWDHNDITFRVLNYSPDLDGDVIEDAFRRA 145
Query: 148 FQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHF 207
F+VWSDV+PL F++I+ GEADIMI FG +HGD YPFDGKDGLLAHA+ PG GV GD+HF
Sbjct: 146 FKVWSDVSPLTFTQIYSGEADIMILFGSDDHGDPYPFDGKDGLLAHAYPPGEGVQGDAHF 205
Query: 208 DDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEK 267
DDDE WTLG G VV+ ++GNA+G CKFPF FNG Y+SCT GR+DG LWCSTT +++K
Sbjct: 206 DDDEFWTLGTGVVVKTRFGNANGAACKFPFKFNGNSYSSCTSEGRTDGLLWCSTTTDYDK 265
Query: 268 DGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDK 327
D KYGFCP E L+T GGN++G C FPF F G SYD+CT EGR+DGYRWC TT+++D+DK
Sbjct: 266 DKKYGFCPSELLYTYGGNSDGDKCVFPFIFDGDSYDACTKEGRSDGYRWCATTDNFDKDK 325
Query: 328 KYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKW 387
KYGFCP + +GGNS+G PCVFPF FL Y SCTS GR D K+WCATT++YD DRKW
Sbjct: 326 KYGFCPNRDTAVIGGNSQGDPCVFPFVFLEKTYHSCTSDGRGDRKLWCATTSSYDSDRKW 385
Query: 388 GFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGA 447
GFCPDQGYSLFLV AHEFGHA+GLEHS ALM P++ Y + F+L QDDI+G+Q LYG+
Sbjct: 386 GFCPDQGYSLFLVGAHEFGHAIGLEHSTVRDALMYPMFRYIEGFQLHQDDIEGVQYLYGS 445
Query: 448 --------------SPDIDXXXXXXXXXXXX----------XXEICKQDIVFDGIAQIRG 483
SPD+ + CK FD I +I G
Sbjct: 446 GTGPHPSPPMPTTKSPDVSGKTTTTVTTSPTTTTELVPVDPTTDACKVK-AFDAITEIEG 504
Query: 484 EIFFFKDRFIWRTVTPRDKPM-GPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWI 542
++ FFKD W+ + R + GP+ ++ WP LP ID+ +E +K FF+G +W+
Sbjct: 505 QLHFFKDGKYWKASSARPGAIKGPVKISDTWPALPAIIDSAFEDLLTKKIFFFSGRRFWV 564
Query: 543 YSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGF 602
Y+ +T+ P+ L LG+ DV+++ + + K +F GDK+WR + + +D G+
Sbjct: 565 YTGTTVLG--PRGLEKLGIGKDVEKIVGSLQRGRG-KVLLFNGDKYWRLDVKTQVVDKGY 621
Query: 603 PKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
P+ DA+ +P N V Q H F K +Y ++ + + + G +K D L C
Sbjct: 622 PRDTEDAFAGVPINAHDVFLYQENIH--FCKDQFYWRMTPRR-QVDQVGYVKYDILNC 676
>sp|P41246|COG9_RABIT 92 KDA TYPE IV COLLAGENASE PRECURSOR (92 KDA GELATINASE) (MATRIX
METALLOPROTEINASE-9) (MMP-9) (GELATINASE B) (GELB)
pir||A53796 gelatinase B (EC 3.4.24.35) precursor - rabbit
dbj|BAA05520.1| (D26514) matrix metalloproteinase 9 [Oryctolagus cuniculus]
Length = 707
Score = 549 bits (1400), Expect = e-155
Identities = 288/684 (42%), Positives = 392/684 (57%), Gaps = 64/684 (9%)
Query: 34 IIKFPGDVAPK-TDKELAVQYLNTFYGCPKESC---NLFVLKDTLKKMQKFFGLPQTGDL 89
++ FPG++ + TD++LA +YL YG + + + L+ L +QK LP+TG+L
Sbjct: 28 LVVFPGELRTRLTDRQLAEEYLFR-YGYTRVASMHGDSQSLRLPLLLLQKHLSLPETGEL 86
Query: 90 DQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQ 149
D T+E MR PRCG PDV + F KW + ITY I Y+ DL + +DDAFARAF
Sbjct: 87 DNATLEAMRAPRCGVPDVGKFQTFEGDLKWHHHNITYWIQNYSEDLPRDVIDDAFARAFA 146
Query: 150 VWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDD 209
+WS VTPL F+R++ +ADI+I FG EHGDGYPFDGKDGLLAHAF PG G+ GD+HFDD
Sbjct: 147 LWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDD 206
Query: 210 DELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDG 269
+ELW+LG+G VV +GNADG C FPF F G+ Y +CT GRSDG WCSTT +++ D
Sbjct: 207 EELWSLGKGVVVPTYFGNADGAPCHFPFTFEGRSYTACTTDGRSDGMAWCSTTADYDTDR 266
Query: 270 KYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKY 329
++GFCP E L+T GNA+G+PC+FPF FQG +Y +CTT+GR+DG+RWC TT YD+DK Y
Sbjct: 267 RFGFCPSERLYTQDGNADGKPCEFPFIFQGRTYSACTTDGRSDGHRWCATTASYDKDKLY 326
Query: 330 GFCPETAMSTV-GGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWG 388
GFCP A STV GGNS G CVFPF FLG +Y SCTS GR DG++WCATT+N+D D+KWG
Sbjct: 327 GFCPTRADSTVVGGNSAGELCVFPFVFLGKEYSSCTSEGRRDGRLWCATTSNFDSDKKWG 386
Query: 389 FCPDQGYSLFLVAAHEFGHAM------------------------------GLEHSQDPG 418
FCPD+GYSLFLVAAHEFGHA+ G++H P
Sbjct: 387 FCPDKGYSLFLVAAHEFGHALGLDHSSVPERLMYPMYRYLEGSPLHEDDVRGIQHLYGPN 446
Query: 419 ALMAPIYTYTKN----------------FRLSQDDIK---GIQELYGASPDIDXXXXXXX 459
P T T R S+ G P
Sbjct: 447 PNPQPPATTTPEPQPTAPPTACPTWPATVRPSEHPTTSPTGAPSAGPTGPPTASPSAAPT 506
Query: 460 XXXXXXXEICKQDIVFDGIAQIRGEIFFFKDRFIWR-TVTPRDKPMGPLLVATFWPELPE 518
++C + VFD IA+I ++ FKD WR + +P GP L+A WP LP
Sbjct: 507 ASLDPAEDVCNVN-VFDAIAEIGNKLHVFKDGRYWRFSEGSGRRPQGPFLIADTWPALPA 565
Query: 519 KIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNK 578
K+D+ +E P +K FF+G + W+Y+ +++ P+ L LGL P+V V A
Sbjct: 566 KLDSAFEEPLTKKLFFFSGRQVWVYTGASVLG--PRRLDKLGLGPEVPHVTGALP-RAGG 622
Query: 579 KTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYL 638
K +F +FWR++ + +D + + +P N V Q +YF + ++
Sbjct: 623 KVLLFGAQRFWRFDVKTQTVDSRSGAPVDQMFPGVPLNTHDV--FQYREKAYFCQDRFFW 680
Query: 639 KLENQSLKSV--KFGSIKSDWLGC 660
++ ++ ++ + G + D L C
Sbjct: 681 RVSTRNEVNLVDQVGYVSFDILHC 704
>emb|CAC10459.1| (AL162458) bA465L10.4 (matrix metalloproteinase 9 (gelatinase B,
92kD gelatinase, 92kD type IV collagenase) (CLG4B))
[Homo sapiens]
Length = 707
Score = 540 bits (1376), Expect = e-152
Identities = 280/581 (48%), Positives = 360/581 (61%), Gaps = 37/581 (6%)
Query: 32 SPIIKFPGDVAPK-TDKELAVQYLNTFYGCPK------ESCNLFVLKDTLKKMQKFFGLP 84
S ++ FPGD+ TD++LA +YL YG + ES +L L +QK LP
Sbjct: 26 STLVLFPGDLRTNLTDRQLAEEYLYR-YGYTRVAEMRGESKSL---GPALLLLQKQLSLP 81
Query: 85 QTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAF 144
+TG+LD T++ MR PRCG PD+ + F KW + ITY I Y+ DL +DDAF
Sbjct: 82 ETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAF 141
Query: 145 ARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGD 204
ARAF +WS VTPL F+R++ +ADI+I FG EHGDGYPFDGKDGLLAHAF PG G+ GD
Sbjct: 142 ARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGD 201
Query: 205 SHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYN 264
+HFDDDELW+LG+G VV ++GNADG C FPF+F G+ Y++CT GRSDG WCSTT N
Sbjct: 202 AHFDDDELWSLGKGVVVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTAN 261
Query: 265 FEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYD 324
++ D ++GFCP E L+T GNA+G+PC+FPF FQG SY +CTT+GR+DGYRWC TT +YD
Sbjct: 262 YDTDDRFGFCPSERLYTQDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYD 321
Query: 325 RDKKYGFCPETAMSTV-GGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDD 383
RDK +GFCP A STV GGNS G CVFPFTFLG +Y +CTS GR DG++WCATT+N+D
Sbjct: 322 RDKLFGFCPTRADSTVMGGNSAGELCVFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDS 381
Query: 384 DRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQE 443
D+KWGFCPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y +T+ L +DD+ GI+
Sbjct: 382 DKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRH 441
Query: 444 LYGASPDID-XXXXXXXXXXXXXXEICK--QDIVFDGIAQIRGEIFFFKDRFIWRTVTPR 500
LYG P+ + +C V G T P
Sbjct: 442 LYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGP-----------TGPPS 490
Query: 501 DKPMGPLL----VATFWPELPEKIDA----VYEAPQE--EKAVFFAGNEYWIYSASTLER 550
P GP AT P P DA +++A E + F +YW +S R
Sbjct: 491 AGPTGPPTAGPSTATTVPLSPVD-DACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSR 549
Query: 551 GYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRY 591
L + P +++D+ F +KK + F+G + W Y
Sbjct: 550 PQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVY 590
Score = 99.1 bits (243), Expect = 1e-19
Identities = 61/190 (32%), Positives = 100/190 (52%), Gaps = 8/190 (4%)
Query: 474 VFDGIAQIRGEIFFFKDRFIWRTVTPR-DKPMGPLLVATFWPELPEKIDAVYEAPQEEKA 532
+FD IA+I +++ FKD WR R +P GP L+A WP LP K+D+V+E +K
Sbjct: 520 IFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQGPFLIADKWPALPRKLDSVFEERLSKKL 579
Query: 533 VFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYN 592
FF+G + W+Y+ +++ P+ L LGL DV +V A S K +F+G + WR++
Sbjct: 580 FFFSGRQVWVYTGASVLG--PRRLDKLGLGADVAQVTGALR-SGRGKMLLFSGRRLWRFD 636
Query: 593 EVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQS-LKSV-KF 650
+ +DP + + +P LD Q +YF + +Y ++ ++S L V +
Sbjct: 637 VKAQMVDPRSASEVDRMFPGVP--LDTHDVFQYREKAYFCQDRFYWRVSSRSELNQVDQV 694
Query: 651 GSIKSDWLGC 660
G + D L C
Sbjct: 695 GYVTYDILQC 704
>pir||A34458 gelatinase B (EC 3.4.24.35) precursor - human
Length = 707
Score = 540 bits (1375), Expect = e-152
Identities = 280/581 (48%), Positives = 360/581 (61%), Gaps = 37/581 (6%)
Query: 32 SPIIKFPGDVAPK-TDKELAVQYLNTFYGCPK------ESCNLFVLKDTLKKMQKFFGLP 84
S ++ FPGD+ TD++LA +YL YG + ES +L L +QK LP
Sbjct: 26 STLVLFPGDLRTNLTDRQLAEEYLYR-YGYTRVAEMRGESKSL---GPALLLLQKQLSLP 81
Query: 85 QTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAF 144
+TG+LD T++ MR PRCG PD+ + F KW + ITY I Y+ DL +DDAF
Sbjct: 82 ETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAF 141
Query: 145 ARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGD 204
ARAF +WS VTPL F+R++ +ADI+I FG EHGDGYPFDGKDGLLAHAF PG G+ GD
Sbjct: 142 ARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGD 201
Query: 205 SHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYN 264
+HFDDDELW+LG+G VV ++GNADG C FPF+F G+ Y++CT GRSDG WCSTT N
Sbjct: 202 AHFDDDELWSLGKGVVVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTAN 261
Query: 265 FEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYD 324
++ D ++GFCP E L+T GNA+G+PC+FPF FQG SY +CTT+GR+DGYRWC TT +YD
Sbjct: 262 YDTDDRFGFCPSERLYTRDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYD 321
Query: 325 RDKKYGFCPETAMSTV-GGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDD 383
RDK +GFCP A STV GGNS G CVFPFTFLG +Y +CTS GR DG++WCATT+N+D
Sbjct: 322 RDKLFGFCPTRADSTVMGGNSAGELCVFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDS 381
Query: 384 DRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQE 443
D+KWGFCPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y +T+ L +DD+ GI+
Sbjct: 382 DKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRH 441
Query: 444 LYGASPDID-XXXXXXXXXXXXXXEICK--QDIVFDGIAQIRGEIFFFKDRFIWRTVTPR 500
LYG P+ + +C V G T P
Sbjct: 442 LYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGP-----------TGPPS 490
Query: 501 DKPMGPLL----VATFWPELPEKIDA----VYEAPQE--EKAVFFAGNEYWIYSASTLER 550
P GP AT P P DA +++A E + F +YW +S R
Sbjct: 491 AGPTGPPTAGPSTATTVPLSPVD-DACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSR 549
Query: 551 GYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRY 591
L + P +++D+ F +KK + F+G + W Y
Sbjct: 550 PQGPFLIADKWPALPRKLDSVFEEPLSKKLFFFSGRQVWVY 590
Score = 102 bits (252), Expect = 1e-20
Identities = 62/190 (32%), Positives = 101/190 (52%), Gaps = 8/190 (4%)
Query: 474 VFDGIAQIRGEIFFFKDRFIWRTVTPR-DKPMGPLLVATFWPELPEKIDAVYEAPQEEKA 532
+FD IA+I +++ FKD WR R +P GP L+A WP LP K+D+V+E P +K
Sbjct: 520 IFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQGPFLIADKWPALPRKLDSVFEEPLSKKL 579
Query: 533 VFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYN 592
FF+G + W+Y+ +++ P+ L LGL DV +V A S K +F+G + WR++
Sbjct: 580 FFFSGRQVWVYTGASVLG--PRRLDKLGLGADVAQVTGALR-SGRGKMLLFSGRRLWRFD 636
Query: 593 EVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQS-LKSV-KF 650
+ +DP + + +P LD Q +YF + +Y ++ ++S L V +
Sbjct: 637 VKAQMVDPRSASEVDRMFPGVP--LDTHDVFQYQEKAYFCQDRFYWRVSSRSELNQVDQV 694
Query: 651 GSIKSDWLGC 660
G + D L C
Sbjct: 695 GYVTYDILQC 704
>ref|NP_004985.1| matrix metalloproteinase 9 (gelatinase B, 92kD gelatinase, 92kD
type IV collagenase); Matrix metalloproteinase 9
(gelatinase B, 92kD type IV collagenase) [Homo sapiens]
sp|P14780|COG9_HUMAN 92 KDA TYPE IV COLLAGENASE PRECURSOR (92 KDA GELATINASE) (MATRIX
METALLOPROTEINASE-9) (MMP-9) (GELATINASE B) (GELB)
gb|AAA51539.1| (J05070) 92 kDa type IV collagenase [Homo sapiens]
Length = 707
Score = 540 bits (1375), Expect = e-152
Identities = 280/581 (48%), Positives = 360/581 (61%), Gaps = 37/581 (6%)
Query: 32 SPIIKFPGDVAPK-TDKELAVQYLNTFYGCPK------ESCNLFVLKDTLKKMQKFFGLP 84
S ++ FPGD+ TD++LA +YL YG + ES +L L +QK LP
Sbjct: 26 STLVLFPGDLRTNLTDRQLAEEYLYR-YGYTRVAEMRGESKSL---GPALLLLQKQLSLP 81
Query: 85 QTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAF 144
+TG+LD T++ MR PRCG PD+ + F KW + ITY I Y+ DL +DDAF
Sbjct: 82 ETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAF 141
Query: 145 ARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGD 204
ARAF +WS VTPL F+R++ +ADI+I FG EHGDGYPFDGKDGLLAHAF PG G+ GD
Sbjct: 142 ARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGD 201
Query: 205 SHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYN 264
+HFDDDELW+LG+G VV ++GNADG C FPF+F G+ Y++CT GRSDG WCSTT N
Sbjct: 202 AHFDDDELWSLGKGVVVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTAN 261
Query: 265 FEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYD 324
++ D ++GFCP E L+T GNA+G+PC+FPF FQG SY +CTT+GR+DGYRWC TT +YD
Sbjct: 262 YDTDDRFGFCPSERLYTRDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYD 321
Query: 325 RDKKYGFCPETAMSTV-GGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDD 383
RDK +GFCP A STV GGNS G CVFPFTFLG +Y +CTS GR DG++WCATT+N+D
Sbjct: 322 RDKLFGFCPTRADSTVMGGNSAGELCVFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDS 381
Query: 384 DRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQE 443
D+KWGFCPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y +T+ L +DD+ GI+
Sbjct: 382 DKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRH 441
Query: 444 LYGASPDID-XXXXXXXXXXXXXXEICK--QDIVFDGIAQIRGEIFFFKDRFIWRTVTPR 500
LYG P+ + +C V G T P
Sbjct: 442 LYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGP-----------TGPPS 490
Query: 501 DKPMGPLL----VATFWPELPEKIDA----VYEAPQE--EKAVFFAGNEYWIYSASTLER 550
P GP AT P P DA +++A E + F +YW +S R
Sbjct: 491 AGPTGPPTAGPSTATTVPLSPVD-DACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSR 549
Query: 551 GYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRY 591
L + P +++D+ F +KK + F+G + W Y
Sbjct: 550 PQGPFLIADKWPALPRKLDSVFEEPLSKKLFFFSGRQVWVY 590
Score = 102 bits (252), Expect = 1e-20
Identities = 62/190 (32%), Positives = 101/190 (52%), Gaps = 8/190 (4%)
Query: 474 VFDGIAQIRGEIFFFKDRFIWRTVTPR-DKPMGPLLVATFWPELPEKIDAVYEAPQEEKA 532
+FD IA+I +++ FKD WR R +P GP L+A WP LP K+D+V+E P +K
Sbjct: 520 IFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQGPFLIADKWPALPRKLDSVFEEPLSKKL 579
Query: 533 VFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYN 592
FF+G + W+Y+ +++ P+ L LGL DV +V A S K +F+G + WR++
Sbjct: 580 FFFSGRQVWVYTGASVLG--PRRLDKLGLGADVAQVTGALR-SGRGKMLLFSGRRLWRFD 636
Query: 593 EVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQS-LKSV-KF 650
+ +DP + + +P LD Q +YF + +Y ++ ++S L V +
Sbjct: 637 VKAQMVDPRSASEVDRMFPGVP--LDTHDVFQYREKAYFCQDRFYWRVSSRSELNQVDQV 694
Query: 651 GSIKSDWLGC 660
G + D L C
Sbjct: 695 GYVTYDILQC 704
>gb|AAD50275.1| (AF169244) matrix metalloproteinase-9 [Canis familiaris]
Length = 704
Score = 533 bits (1359), Expect = e-150
Identities = 245/421 (58%), Positives = 306/421 (72%), Gaps = 4/421 (0%)
Query: 34 IIKFPGDVAPK-TDKELAVQYLNTF-YGCPKE-SCNLFVLKDTLKKMQKFFGLPQTGDLD 90
++ FPGD+ TDK+LA +YL + Y E S + L L+ +Q+ LP+TG+LD
Sbjct: 28 VVVFPGDLRTNLTDKQLAEEYLFRYGYTQVAELSDDKQSLSRGLRLLQRRLALPETGELD 87
Query: 91 QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV 150
+ T+E MR PRCG PD+ + F KW N ITY I Y+ DL + +DDAFARAF V
Sbjct: 88 KTTLEAMRAPRCGVPDLGKFQTFEGDLKWHHNDITYWIQNYSEDLPRDVIDDAFARAFAV 147
Query: 151 WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD 210
WS VTPL F+R++ EADI+I FG EHGDGYPFDGK+GLLAHAF PG G+ GD+HFDD+
Sbjct: 148 WSAVTPLTFTRVYGPEADIIIQFGVREHGDGYPFDGKNGLLAHAFPPGPGIQGDAHFDDE 207
Query: 211 ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK 270
ELWTLG+G VV +GNADG C FPF F G+ Y++CT GRSD WCSTT +++ D +
Sbjct: 208 ELWTLGKGVVVPTHFGNADGAPCHFPFTFEGRSYSACTTDGRSDDTPWCSTTADYDTDRR 267
Query: 271 YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG 330
+GFCP E L+T GN +G+PC FPF F+G SY +CTT+GR+DGYRWC TT DYD+DK YG
Sbjct: 268 FGFCPSEKLYTQDGNGDGKPCVFPFTFEGRSYSTCTTDGRSDGYRWCSTTGDYDQDKLYG 327
Query: 331 FCPETAMSTV-GGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGF 389
FCP S V GGNS G PCVFPF FLG +Y +CT GR DG +WCATT+N+D D+KWGF
Sbjct: 328 FCPTRVDSAVTGGNSAGEPCVFPFIFLGKQYSTCTREGRGDGHLWCATTSNFDRDKKWGF 387
Query: 390 CPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASP 449
CPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y++T+ L +DD++GIQ LYG P
Sbjct: 388 CPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYSFTEGPPLHEDDVRGIQHLYGPRP 447
Query: 450 D 450
+
Sbjct: 448 E 448
Score = 93.2 bits (228), Expect = 8e-18
Identities = 57/197 (28%), Positives = 100/197 (49%), Gaps = 9/197 (4%)
Query: 467 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPM-GPLLVATFWPELPEKIDAVYE 525
+ICK +I FD IA+IR + FFK+ WR + + + GP L+ WP LP K+D+ +E
Sbjct: 511 DICKVNI-FDAIAEIRNYLHFFKEGKYWRFSKGKGRRVQGPFLITDTWPALPRKLDSAFE 569
Query: 526 APQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAG 585
+K FF+G + W+Y+ +++ P+ L LGL P+V +V A K +F+
Sbjct: 570 DGLTKKTFFFSGRQVWVYTGTSVVG--PRRLDKLGLGPEVTQVTGALP-QGGGKVLLFSR 626
Query: 586 DKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKL--ENQ 643
+FW ++ + +DP + + +P N + Q +YF + +Y ++ N+
Sbjct: 627 QRFWSFDVKTQTVDPRSAGSVEQMYPGVPLNTHDIFQYQ--EKAYFCQDRFYWRVNSRNE 684
Query: 644 SLKSVKFGSIKSDWLGC 660
+ + G + D L C
Sbjct: 685 VNQVDEVGYVTFDILQC 701
>dbj|BAA22087.3| (AB006421) matrix metalloproteinase-9 [Canis familiaris]
Length = 704
Score = 532 bits (1356), Expect = e-150
Identities = 244/421 (57%), Positives = 304/421 (71%), Gaps = 4/421 (0%)
Query: 34 IIKFPGDVAPK-TDKELAVQYLNTF-YGCPKESCN-LFVLKDTLKKMQKFFGLPQTGDLD 90
++ FPGD+ TDK+LA +YL + Y E N L L+ +Q+ LP+TG+LD
Sbjct: 28 VVVFPGDLRTNLTDKQLAEEYLFRYGYTQVAELSNDKQSLSRGLRLLQRRLALPETGELD 87
Query: 91 QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV 150
+ T+E MR PRCG PD+ + F KW N ITY I Y+ DL + +DDAFARAF V
Sbjct: 88 KTTLEAMRAPRCGVPDLGKFQTFEGDLKWHHNDITYWIQNYSEDLPRDVIDDAFARAFAV 147
Query: 151 WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD 210
WS VTPL F+R++ EADI+I FG EHGDGYPFDGK+GLLAHAF PG G+ GD+HFDD+
Sbjct: 148 WSAVTPLTFTRVYGPEADIIIQFGVREHGDGYPFDGKNGLLAHAFPPGPGIQGDAHFDDE 207
Query: 211 ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK 270
ELWTLG+G VV +GNADG C FPF F G+ Y++CT GRSD WCSTT +++ D +
Sbjct: 208 ELWTLGKGVVVPTHFGNADGAPCHFPFTFEGRSYSACTTDGRSDDTPWCSTTADYDTDRR 267
Query: 271 YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG 330
+GFCP E L+ GN +G+PC FPF F+G SY +CTT+GR+DGYRWC TT DYD+DK YG
Sbjct: 268 FGFCPSEKLYAQDGNGDGKPCVFPFTFEGRSYSTCTTDGRSDGYRWCSTTADYDQDKLYG 327
Query: 331 FCPETAMSTV-GGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGF 389
FCP S V GGNS G PCVFPF FLG +Y +CT GR DG +WCATT+N+D D+KWGF
Sbjct: 328 FCPTRVDSAVTGGNSAGEPCVFPFIFLGKQYSTCTREGRGDGHLWCATTSNFDRDKKWGF 387
Query: 390 CPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASP 449
CPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y++T+ L +DD++GIQ LYG P
Sbjct: 388 CPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYSFTEGPPLHEDDVRGIQHLYGPRP 447
Query: 450 D 450
+
Sbjct: 448 E 448
Score = 91.7 bits (224), Expect = 2e-17
Identities = 57/197 (28%), Positives = 100/197 (49%), Gaps = 9/197 (4%)
Query: 467 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPM-GPLLVATFWPELPEKIDAVYE 525
+ICK +I FD IA+IR + FFK+ WR + + + GP L + WP LP K+D+ +E
Sbjct: 511 DICKVNI-FDAIAEIRNYLHFFKEGKYWRFSKGKGRRVQGPFLSPSTWPALPRKLDSAFE 569
Query: 526 APQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAG 585
+K FF+G + W+Y+ +++ P+ L LGL P+V +V A K +F+
Sbjct: 570 DGLTKKTFFFSGRQVWVYTGTSVVG--PRRLDKLGLGPEVTQVTGALP-QGGGKVLLFSR 626
Query: 586 DKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKL--ENQ 643
+FW ++ + +DP + + +P N + Q +YF + +Y ++ N+
Sbjct: 627 QRFWSFDVKTQTVDPRSAGSVEQMYPGVPLNTHDIFQYQ--EKAYFCQDRFYWRVNSRNE 684
Query: 644 SLKSVKFGSIKSDWLGC 660
+ + G + D L C
Sbjct: 685 VNQVDEVGYVTFDILQC 701
>gb|AAB81681.1| (U89842) gelatinase B [Canis familiaris]
Length = 704
Score = 531 bits (1353), Expect = e-149
Identities = 243/421 (57%), Positives = 304/421 (71%), Gaps = 4/421 (0%)
Query: 34 IIKFPGDVAPK-TDKELAVQYLNTF-YGCPKESCN-LFVLKDTLKKMQKFFGLPQTGDLD 90
++ FPGD+ TDK+LA +YL + Y E N L L+ +Q+ LP+TG+LD
Sbjct: 28 VVVFPGDLRTNLTDKQLAEEYLFRYGYTQVAELSNDKQSLSRGLRLLQRRLALPETGELD 87
Query: 91 QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV 150
+ T+E MR PRCG PD+ + F KW N ITY I Y+ +L + +DDAFARAF V
Sbjct: 88 KTTLEAMRAPRCGVPDLGKFQTFEGDLKWHHNDITYWIQNYSEELPRDVIDDAFARAFAV 147
Query: 151 WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD 210
WS VTPL F+R++ EADI+I FG EHGDGYPFDGK+GLLAHAF PG G+ GD+HFDD+
Sbjct: 148 WSAVTPLTFTRVYGPEADIIIQFGVREHGDGYPFDGKNGLLAHAFPPGPGIQGDAHFDDE 207
Query: 211 ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK 270
ELWTLG+G VV +GNADG C FPF F G+ Y++CT GRSD WCSTT +++ D +
Sbjct: 208 ELWTLGKGVVVPTHFGNADGAPCHFPFTFEGRSYSACTTDGRSDDTPWCSTTADYDTDRR 267
Query: 271 YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG 330
+GFCP E +T GN +G+PC FPF F+G SY +CTT+GR+DGYRWC TT DYD+DK YG
Sbjct: 268 FGFCPSEKFYTQDGNGDGKPCVFPFTFEGRSYSTCTTDGRSDGYRWCSTTADYDQDKLYG 327
Query: 331 FCPETAMSTV-GGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGF 389
FCP S V GGNS G PCVFPF FLG +Y +CT GR DG +WCATT+N+D D+KWGF
Sbjct: 328 FCPTRVDSAVTGGNSAGEPCVFPFIFLGKQYSTCTREGRGDGHLWCATTSNFDRDKKWGF 387
Query: 390 CPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASP 449
CPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y++T+ L +DD++GIQ LYG P
Sbjct: 388 CPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYSFTEGPPLHEDDVRGIQHLYGPRP 447
Query: 450 D 450
+
Sbjct: 448 E 448
Score = 93.2 bits (228), Expect = 8e-18
Identities = 57/197 (28%), Positives = 100/197 (49%), Gaps = 9/197 (4%)
Query: 467 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPM-GPLLVATFWPELPEKIDAVYE 525
+ICK +I FD IA+IR + FFK+ WR + + + GP L+ WP LP K+D+ +E
Sbjct: 511 DICKVNI-FDAIAEIRNYLHFFKEGKYWRFSKGKGRRVQGPFLITDTWPALPRKLDSAFE 569
Query: 526 APQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAG 585
+K FF+G + W+Y+ +++ P+ L LGL P+V +V A K +F+
Sbjct: 570 DGLTKKTFFFSGRQVWVYTGTSVVG--PRRLDKLGLGPEVTQVTGALP-QGGGKVLLFSR 626
Query: 586 DKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKL--ENQ 643
+FW ++ + +DP + + +P N + Q +YF + +Y ++ N+
Sbjct: 627 QRFWSFDVKTQTVDPRSAGSVEQMYPGVPLNTHDIFQYQ--EKAYFCQDRFYWRVNSRNE 684
Query: 644 SLKSVKFGSIKSDWLGC 660
+ + G + D L C
Sbjct: 685 VNQVDEVGYVTFDILQC 701
>pir||I52580 gelatinase B (EC 3.4.24.35) precursor - mouse
gb|AAB28942.1| (S67830) type IV collagenase, gelatinase=matrix metalloproteinase
[mice, macrophage 32D C13 cells, Peptide, 730 aa] [Mus
sp.]
Length = 730
Score = 529 bits (1347), Expect = e-149
Identities = 248/424 (58%), Positives = 308/424 (72%), Gaps = 10/424 (2%)
Query: 35 IKFPGDVAPK--TDKELAVQYLNTFYGCPKESCNLFV---LKDTLKKMQKFFGLPQTGDL 89
+ FP D+ TD +LA YL YG + + + L+ L +QK LPQTG+L
Sbjct: 29 VVFPKDLKTSNLTDTQLAEAYLYR-YGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGEL 87
Query: 90 DQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQ 149
D T++ +R PRCG PDV + F + KWD + ITY I Y+ DL + +DDAFARAF
Sbjct: 88 DSQTLKAIRTPRCGVPDVGRFQTF-KGLKWDHHNITYWIQNYSEDLPRDMIDDAFARAFA 146
Query: 150 VWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDD 209
VW +V PL F+R++ EADI+I FG EHGDGYPFDGKDGLLAHAF PG GV GD+HFDD
Sbjct: 147 VWGEVAPLTFTRVYGPEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGAGVQGDAHFDD 206
Query: 210 DELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDG 269
DELW+LG+G V+ YGN++G C FPF F G+ Y++CT GR+DG WCSTT +++KDG
Sbjct: 207 DELWSLGKGVVIPTYYGNSNGAPCHFPFTFEGRSYSACTTDGRNDGTPWCSTTADYDKDG 266
Query: 270 KYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKY 329
K+GFCP E L+T GN EG+PC FPF F+G SY +CTT+GR+DGYRWC TT +YD+DK Y
Sbjct: 267 KFGFCPSERLYTEHGNGEGKPCVFPFIFEGRSYSACTTKGRSDGYRWCATTANYDQDKLY 326
Query: 330 GFCPETAMST-VGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWG 388
GFCP +T VGGNS G CVFPF FLG +Y SCTS GR DG++WCATT+N+D D+KWG
Sbjct: 327 GFCPTRVDATVVGGNSAGELCVFPFVFLGKQYSSCTSDGRRDGRLWCATTSNFDTDKKWG 386
Query: 389 FCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELY--G 446
FCPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y+Y + F L++DDI GIQ LY G
Sbjct: 387 FCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPLYSYLEGFPLNKDDIDGIQYLYGRG 446
Query: 447 ASPD 450
+ PD
Sbjct: 447 SKPD 450
Score = 102 bits (253), Expect = 9e-21
Identities = 56/177 (31%), Positives = 94/177 (52%), Gaps = 7/177 (3%)
Query: 469 CKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPM-GPLLVATFWPELPEKIDAVYEAP 527
C D VFD IA+I+G + FFKD + W+ + R P+ GP L A WP LP +D+ +E P
Sbjct: 534 CNVD-VFDAIAEIQGALHFFKDGWYWKFLNHRGSPLQGPFLTARTWPALPATLDSAFEDP 592
Query: 528 QEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDK 587
Q ++ FF+G + W+Y+ T+ P+ L LGL P+V V + K +F+ +
Sbjct: 593 QTKRVFFFSGRQMWVYTGKTVLG--PRSLDKLGLGPEVTHVSGLLP-RRPGKALLFSKGR 649
Query: 588 FWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQS 644
WR++ +K+DP + ++ +P N + Q +YF G ++ ++ Q+
Sbjct: 650 VWRFDLKSQKVDPQSVIRVDKEFSGVPWNSHDIFQYQ--DKAYFCHGKFFWRVSFQN 704
>ref|NP_038627.1| matrix metalloproteinase 9; Gel B; gelatinase B; 92kD gelatinase;
92kD type IV collagenase [Mus musculus]
emb|CAA51314.1| (X72794) gelatinase b [Mus musculus]
Length = 730
Score = 529 bits (1347), Expect = e-149
Identities = 248/424 (58%), Positives = 308/424 (72%), Gaps = 10/424 (2%)
Query: 35 IKFPGDVAPK--TDKELAVQYLNTFYGCPKESCNLFV---LKDTLKKMQKFFGLPQTGDL 89
+ FP D+ TD +LA YL YG + + + L+ L +QK LPQTG+L
Sbjct: 29 VVFPKDLKTSNLTDTQLAEAYLYR-YGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGEL 87
Query: 90 DQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQ 149
D T++ +R PRCG PDV + F + KWD + ITY I Y+ DL + +DDAFARAF
Sbjct: 88 DSQTLKAIRTPRCGVPDVGRFQTF-KGLKWDHHNITYWIQNYSEDLPRDMIDDAFARAFA 146
Query: 150 VWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDD 209
VW +V PL F+R++ EADI+I FG EHGDGYPFDGKDGLLAHAF PG GV GD+HFDD
Sbjct: 147 VWGEVAPLTFTRVYGPEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGAGVQGDAHFDD 206
Query: 210 DELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDG 269
DELW+LG+G V+ YGN++G C FPF F G+ Y++CT GR+DG WCSTT +++KDG
Sbjct: 207 DELWSLGKGVVIPTYYGNSNGAPCHFPFTFEGRSYSACTTDGRNDGTPWCSTTADYDKDG 266
Query: 270 KYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKY 329
K+GFCP E L+T GN EG+PC FPF F+G SY +CTT+GR+DGYRWC TT +YD+DK Y
Sbjct: 267 KFGFCPSERLYTEHGNGEGKPCVFPFIFEGRSYSACTTKGRSDGYRWCATTANYDQDKLY 326
Query: 330 GFCPETAMST-VGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWG 388
GFCP +T VGGNS G CVFPF FLG +Y SCTS GR DG++WCATT+N+D D+KWG
Sbjct: 327 GFCPTRVDATVVGGNSAGELCVFPFVFLGKQYSSCTSDGRRDGRLWCATTSNFDTDKKWG 386
Query: 389 FCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELY--G 446
FCPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y+Y + F L++DDI GIQ LY G
Sbjct: 387 FCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPLYSYLEGFPLNKDDIDGIQYLYGRG 446
Query: 447 ASPD 450
+ PD
Sbjct: 447 SKPD 450
>sp|P41245|COG9_MOUSE 92 KDA TYPE IV COLLAGENASE PRECURSOR (92 KDA GELATINASE) (MATRIX
METALLOPROTEINASE-9) (MMP-9) (GELATINASE B) (GELB)
emb|CAA81745.1| (Z27231) CLG4B [Mus musculus]
Length = 730
Score = 529 bits (1347), Expect = e-149
Identities = 248/424 (58%), Positives = 308/424 (72%), Gaps = 10/424 (2%)
Query: 35 IKFPGDVAPK--TDKELAVQYLNTFYGCPKESCNLFV---LKDTLKKMQKFFGLPQTGDL 89
+ FP D+ TD +LA YL YG + + + L+ L +QK LPQTG+L
Sbjct: 29 VVFPKDLKTSNLTDTQLAEAYLYR-YGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGEL 87
Query: 90 DQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQ 149
D T++ +R PRCG PDV + F + KWD + ITY I Y+ DL + +DDAFARAF
Sbjct: 88 DSQTLKAIRTPRCGVPDVGRFQTF-KGLKWDHHNITYWIQNYSEDLPRDMIDDAFARAFA 146
Query: 150 VWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDD 209
VW +V PL F+R++ EADI+I FG EHGDGYPFDGKDGLLAHAF PG GV GD+HFDD
Sbjct: 147 VWGEVAPLTFTRVYGPEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGAGVQGDAHFDD 206
Query: 210 DELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDG 269
DELW+LG+G V+ YGN++G C FPF F G+ Y++CT GR+DG WCSTT +++KDG
Sbjct: 207 DELWSLGKGVVIPTYYGNSNGAPCHFPFTFEGRSYSACTTDGRNDGTPWCSTTADYDKDG 266
Query: 270 KYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKY 329
K+GFCP E L+T GN EG+PC FPF F+G SY +CTT+GR+DGYRWC TT +YD+DK Y
Sbjct: 267 KFGFCPSERLYTEHGNGEGKPCVFPFIFEGRSYSACTTKGRSDGYRWCATTANYDQDKLY 326
Query: 330 GFCPETAMST-VGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWG 388
GFCP +T VGGNS G CVFPF FLG +Y SCTS GR DG++WCATT+N+D D+KWG
Sbjct: 327 GFCPTRVDATVVGGNSAGELCVFPFVFLGKQYSSCTSDGRRDGRLWCATTSNFDTDKKWG 386
Query: 389 FCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELY--G 446
FCPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y+Y + F L++DDI GIQ LY G
Sbjct: 387 FCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPLYSYLEGFPLNKDDIDGIQYLYGRG 446
Query: 447 ASPD 450
+ PD
Sbjct: 447 SKPD 450
Score = 102 bits (253), Expect = 9e-21
Identities = 56/177 (31%), Positives = 94/177 (52%), Gaps = 7/177 (3%)
Query: 469 CKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPM-GPLLVATFWPELPEKIDAVYEAP 527
C D VFD IA+I+G + FFKD + W+ + R P+ GP L A WP LP +D+ +E P
Sbjct: 534 CNVD-VFDAIAEIQGALHFFKDGWYWKFLNHRGSPLQGPFLTARTWPALPATLDSAFEDP 592
Query: 528 QEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDK 587
Q ++ FF+G + W+Y+ T+ P+ L LGL P+V V + K +F+ +
Sbjct: 593 QTKRVFFFSGRQMWVYTGKTVLG--PRSLDKLGLGPEVTHVSGLLP-RRPGKALLFSKGR 649
Query: 588 FWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQS 644
WR++ +K+DP + ++ +P N + Q +YF G ++ ++ Q+
Sbjct: 650 VWRFDLKSQKVDPQSVIRVDKEFSGVPWNSHDIFQYQ--DKAYFCHGKFFWRVSFQN 704
>pir||JC1456 gelatinase B (EC 3.4.24.35) precursor - mouse
dbj|BAA02208.1| (D12712) gelatinase [Mus musculus]
Length = 730
Score = 529 bits (1347), Expect = e-149
Identities = 248/424 (58%), Positives = 308/424 (72%), Gaps = 10/424 (2%)
Query: 35 IKFPGDVAPK--TDKELAVQYLNTFYGCPKESCNLFV---LKDTLKKMQKFFGLPQTGDL 89
+ FP D+ TD +LA YL YG + + + L+ L +QK LPQTG+L
Sbjct: 29 VVFPKDLKTSNLTDTQLAEAYLYR-YGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGEL 87
Query: 90 DQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQ 149
D T++ +R PRCG PDV + F + KWD + ITY I Y+ DL + +DDAFARAF
Sbjct: 88 DSQTLKAIRTPRCGVPDVGRFQTF-KGLKWDHHNITYWIQNYSEDLPRDMIDDAFARAFA 146
Query: 150 VWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDD 209
VW +V PL F+R++ EADI+I FG EHGDGYPFDGKDGLLAHAF PG GV GD+HFDD
Sbjct: 147 VWGEVAPLTFTRVYGPEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGAGVQGDAHFDD 206
Query: 210 DELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDG 269
DELW+LG+G V+ YGN++G C FPF F G+ Y++CT GR+DG WCSTT +++KDG
Sbjct: 207 DELWSLGKGVVIPTYYGNSNGAPCHFPFTFEGRSYSACTTDGRNDGTPWCSTTADYDKDG 266
Query: 270 KYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKY 329
K+GFCP E L+T GN EG+PC FPF F+G SY +CTT+GR+DGYRWC TT +YD+DK Y
Sbjct: 267 KFGFCPSERLYTEHGNGEGKPCVFPFIFEGRSYSACTTKGRSDGYRWCATTANYDQDKLY 326
Query: 330 GFCPETAMST-VGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWG 388
GFCP +T VGGNS G CVFPF FLG +Y SCTS GR DG++WCATT+N+D D+KWG
Sbjct: 327 GFCPTRVDATVVGGNSAGELCVFPFVFLGKQYSSCTSDGRRDGRLWCATTSNFDTDKKWG 386
Query: 389 FCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELY--G 446
FCPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y+Y + F L++DDI GIQ LY G
Sbjct: 387 FCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPLYSYLEGFPLNKDDIDGIQYLYGRG 446
Query: 447 ASPD 450
+ PD
Sbjct: 447 SKPD 450
>sp|O18733|COG9_CANFA 92 KDA TYPE IV COLLAGENASE PRECURSOR (92 KDA GELATINASE) (MATRIX
METALLOPROTEINASE-9) (MMP-9) (GELATINASE B) (GELB)
Length = 704
Score = 527 bits (1343), Expect = e-148
Identities = 243/421 (57%), Positives = 303/421 (71%), Gaps = 4/421 (0%)
Query: 34 IIKFPGDVAPK-TDKELAVQYLNTF-YGCPKESCN-LFVLKDTLKKMQKFFGLPQTGDLD 90
++ FPGD+ TDK+LA +YL + Y E N L L+ +Q+ LP+TG+LD
Sbjct: 28 VVVFPGDLRTNLTDKQLAEEYLFRYGYTQVAELSNDKQSLSRGLRLLQRRLALPETGELD 87
Query: 91 QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV 150
+ T+E MR PR PD+ + F KW N ITY I Y+ DL + +DDAFARAF V
Sbjct: 88 KTTLEAMRAPRWAFPDLGKFQTFEGDLKWHHNDITYWIQNYSEDLPRDVIDDAFARAFAV 147
Query: 151 WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD 210
WS VTPL F+R++ EADI+I FG EHGDGYPFDGK+GLLAHAFAPG + GD+HFDD+
Sbjct: 148 WSAVTPLTFTRVYGPEADIIIQFGVREHGDGYPFDGKNGLLAHAFAPGPAIQGDAHFDDE 207
Query: 211 ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK 270
ELWTLG+G VV +GNADG C FPF F G+ Y++CT GRSD WCSTT +++ D +
Sbjct: 208 ELWTLGKGVVVPTHFGNADGAPCHFPFTFEGRSYSACTTDGRSDDTPWCSTTADYDTDRR 267
Query: 271 YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG 330
+GFCP E L+T GN +G+PC FPF F+G SY +CTT+GR+DGYRWC TT DYD+DK YG
Sbjct: 268 FGFCPSEKLYTQDGNGDGKPCVFPFTFEGRSYSTCTTDGRSDGYRWCSTTADYDQDKLYG 327
Query: 331 FCPETAMSTV-GGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGF 389
FCP S V GGNS G PCVFPF FLG +Y +CT GR DG +WCATT+N+D D+KWGF
Sbjct: 328 FCPTRVDSAVTGGNSAGEPCVFPFIFLGKQYSTCTREGRGDGHLWCATTSNFDRDKKWGF 387
Query: 390 CPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASP 449
CPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y++T+ L +DD++GIQ LYG P
Sbjct: 388 CPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYSFTEGPPLHEDDVRGIQHLYGPRP 447
Query: 450 D 450
+
Sbjct: 448 E 448
Score = 92.1 bits (225), Expect = 2e-17
Identities = 57/197 (28%), Positives = 100/197 (49%), Gaps = 9/197 (4%)
Query: 467 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPM-GPLLVATFWPELPEKIDAVYE 525
+ICK +I FD IA+IR + FFK+ WR + + + GP L + WP LP K+D+ +E
Sbjct: 511 DICKVNI-FDAIAEIRNYLHFFKEGKYWRFSKGKGRRVQGPFLSPSTWPALPRKLDSAFE 569
Query: 526 APQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAG 585
+K FF+G + W+Y+ +++ P+ L LGL P+V +V A K +F+
Sbjct: 570 DGLTKKTFFFSGRQVWVYTGTSVVG--PRRLDKLGLGPEVTQVTGALP-QAGGKVLLFSR 626
Query: 586 DKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKL--ENQ 643
+FW ++ + +DP + + +P N + Q +YF + +Y ++ N+
Sbjct: 627 QRFWSFDVKTQTVDPRSAGSVEQMYPGVPLNTHDIFQYQ--EKAYFCQDRFYWRVNSRNE 684
Query: 644 SLKSVKFGSIKSDWLGC 660
+ + G + D L C
Sbjct: 685 VNQVDEVGYVTFDILQC 701
>sp|P52176|COG9_BOVIN 92 KDA TYPE IV COLLAGENASE PRECURSOR (92 KDA GELATINASE) (MATRIX
METALLOPROTEINASE-9) (MMP-9) (GELATINASE B) (GELB)
pir||S43112 gelatinase B (EC 3.4.24.35) - bovine
pir||I46031 gelatinase B (EC 3.4.24.35) - bovine
emb|CAA55127.1| (X78324) matrix metalloproteinase 9 [Bos taurus]
Length = 712
Score = 525 bits (1338), Expect = e-148
Identities = 264/574 (45%), Positives = 351/574 (60%), Gaps = 22/574 (3%)
Query: 34 IIKFPGDVAPK-TDKELAVQYLNTFYGCP--KESCNLFVLKDTLKKMQKFFGLPQTGDLD 90
++ FPG+ T+++LA +YL + P + S + L+ L + Q+ LP+TG+LD
Sbjct: 28 VVVFPGEPRTNLTNRQLAEEYLYRYGYTPGAELSEDGQSLQRALLRFQRRLSLPETGELD 87
Query: 91 QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV 150
T+ MR PRCG PDV + F + KW + ITY I Y+ DL +DDAFARAF +
Sbjct: 88 STTLNAMRAPRCGVPDVGRFQTFEGELKWHHHNITYWIQNYSEDLPRAVIDDAFARAFAL 147
Query: 151 WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD 210
WS VTPL F+R++ EADI+I FG EHGDGYPFDGK+GLLAHAF PG G+ GD+HFDD+
Sbjct: 148 WSAVTPLTFTRVYGPEADIVIQFGVREHGDGYPFDGKNGLLAHAFPPGKGIQGDAHFDDE 207
Query: 211 ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK 270
ELW+LG+G V+ +GNA G C FPF F G+ Y++CT GRSD LWCSTT +++ D +
Sbjct: 208 ELWSLGKGVVIPTYFGNAKGAACHFPFTFEGRSYSACTTDGRSDDMLWCSTTADYDADRQ 267
Query: 271 YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYG 330
+GFCP E L+T GNA+G+PC FPF FQG +Y +CT++GR+DGYRWC TT +YD+DK YG
Sbjct: 268 FGFCPSERLYTQDGNADGKPCVFPFTFQGRTYSACTSDGRSDGYRWCATTANYDQDKLYG 327
Query: 331 FCPETAMSTV-GGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGF 389
FCP +TV GGN+ G CVFPFTFLG +Y +CT GR+DG +WCATT+N+D D+KWGF
Sbjct: 328 FCPTRVDATVTGGNAAGELCVFPFTFLGKEYSACTREGRNDGHLWCATTSNFDKDKKWGF 387
Query: 390 CPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASP 449
CPDQGYSLFLVAAHEFGHA+GL+H+ P ALM P+Y +T+ L +DD++GIQ LYG P
Sbjct: 388 CPDQGYSLFLVAAHEFGHALGLDHTSVPEALMYPMYRFTEEHPLHRDDVQGIQHLYGPRP 447
Query: 450 DIDXXXXXXXXXXXXXXE-ICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKP----- 503
+ + + + G R + T P P
Sbjct: 448 EPEPRPPTTTTTTTTEPQPTAPPTVCVTGPPTARPS----EGPTTGPTGPPAAGPTGPPT 503
Query: 504 MGPLLVATFWPELPEKI------DAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLT 557
GP T P+ E + DA+ E + FF +YW S R L
Sbjct: 504 AGPSAAPTESPDPAEDVCNVDIFDAIAEI--RNRLHFFKAGKYWRLSEGGGRRVQGPFLV 561
Query: 558 SLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRY 591
P +++D+AF KK + F+G + W Y
Sbjct: 562 KSKWPALPRKLDSAFEDPLTKKIFFFSGRQVWVY 595
Score = 101 bits (249), Expect = 3e-20
Identities = 62/197 (31%), Positives = 104/197 (52%), Gaps = 9/197 (4%)
Query: 467 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPM-GPLLVATFWPELPEKIDAVYE 525
++C DI FD IA+IR + FFK WR + + GP LV + WP LP K+D+ +E
Sbjct: 519 DVCNVDI-FDAIAEIRNRLHFFKAGKYWRLSEGGGRRVQGPFLVKSKWPALPRKLDSAFE 577
Query: 526 APQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAG 585
P +K FF+G + W+Y+ ++L P+ L LGL P+V +V A + K +F+G
Sbjct: 578 DPLTKKIFFFSGRQVWVYTGASLLG--PRRLDKLGLGPEVAQVTGALPRPEG-KVLLFSG 634
Query: 586 DKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQS- 644
FWR++ +K+DP + + +P + + Q +YF + +Y ++ +Q+
Sbjct: 635 QSFWRFDVKTQKVDPQSVTPVDQMFPGVPISTHDIFQYQ--EKAYFCQDHFYWRVSSQNE 692
Query: 645 LKSVKF-GSIKSDWLGC 660
+ V + G + D L C
Sbjct: 693 VNQVDYVGYVTFDLLKC 709
>pir||JC4364 gelatinase B (EC 3.4.24.35) precursor - rat
gb|AAA90911.1| (U24441) gelatinase B [Rattus norvegicus]
Length = 708
Score = 524 bits (1336), Expect = e-147
Identities = 279/580 (48%), Positives = 351/580 (60%), Gaps = 38/580 (6%)
Query: 35 IKFPGDVAPK--TDKELAVQYLNTFYGCPKESCNLFV---LKDTLKKMQKFFGLPQTGDL 89
+ FP D+ TD +LA YL YG + + + L+ L +QK LPQTG+L
Sbjct: 29 VVFPRDLKTSNLTDTQLAEDYLYR-YGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGEL 87
Query: 90 DQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQ 149
D T++ +R PRCG PDV + F KW + ITY I YT DL + +DD+FARAF
Sbjct: 88 DSETLKAIRSPRCGVPDVGKFQTFEGDLKWHHHNITYWIQSYTEDLPRDVIDDSFARAFA 147
Query: 150 VWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDD 209
VWS VTPL F+R++ EADI+I FG EHGDGYPFDGKDGLLAHAF PG G+ GD+HFDD
Sbjct: 148 VWSAVTPLTFTRVYGLEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDD 207
Query: 210 DELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDG 269
DELW+LG+G VV +GNA+G C FPF F G+ Y SCT GR+DG WC TT +++ D
Sbjct: 208 DELWSLGKGAVVPTYFGNANGAPCHFPFTFEGRSYLSCTTDGRNDGKPWCGTTADYDTDR 267
Query: 270 KYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKY 329
KYGFCP E L+T GN +G+PC FPF F+G SY +CTT+GR+DGYRWC TT +YD+DK Y
Sbjct: 268 KYGFCPSENLYTEHGNGDGKPCVFPFIFEGHSYSACTTKGRSDGYRWCATTANYDQDKLY 327
Query: 330 GFCPETAMSTV-GGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWG 388
GFCP A TV GGNS G CVFPF FLG +Y +CT GRSDG++WCATT+N+D D+KWG
Sbjct: 328 GFCPTRADVTVTGGNSAGEMCVFPFVFLGKQYSTCTGEGRSDGRLWCATTSNFDADKKWG 387
Query: 389 FCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGAS 448
FCPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y Y ++ L +DDIKGIQ LYG
Sbjct: 388 FCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYHYHEDSPLHEDDIKGIQHLYGRG 447
Query: 449 PDIDXXXXXXXXXXXXXXEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPM-GPL 507
D +A G TV P P GP
Sbjct: 448 SKPDPRPPATTAAEPQPTAPPTMCPTAPPMAYPTG----------GPTVAPTGAPSPGPT 497
Query: 508 LVATFWP-----------ELPEKIDAVYEAPQEEKAV--FFAGNEYWIYS---ASTLERG 551
T P + P +D V++A + + FF YW +S S L+
Sbjct: 498 GPPTAGPSEAPTESSTPVDNPCNVD-VFDAIADIQGALHFFKDGRYWKFSNHGGSQLQGP 556
Query: 552 YPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRY 591
+ T LP ++++AF ++KK + F+G K W Y
Sbjct: 557 FLIARTWPALP---AKLNSAFEDPQSKKIFFFSGRKMWVY 593
Score = 89.3 bits (218), Expect = 1e-16
Identities = 52/173 (30%), Positives = 88/173 (50%), Gaps = 7/173 (4%)
Query: 469 CKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPM-GPLLVATFWPELPEKIDAVYEAP 527
C D VFD IA I+G + FFKD W+ + GP L+A WP LP K+++ +E P
Sbjct: 519 CNVD-VFDAIADIQGALHFFKDGRYWKFSNHGGSQLQGPFLIARTWPALPAKLNSAFEDP 577
Query: 528 QEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDK 587
Q +K FF+G + W+Y+ T+ P+ L LGL +V V + K + + ++
Sbjct: 578 QSKKIFFFSGRKMWVYTGQTVLG--PRSLDKLGLGSEVTLVTGLLP-RRGGKALLISRER 634
Query: 588 FWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKL 640
W+++ +K+DP + + ++ +P N V Q +YF Y+ ++
Sbjct: 635 IWKFDLKSQKVDPQSVTRLDNEFSGVPWNSHNVFHYQ--DKAYFCHDKYFWRV 685
>pir||S62907 gelatinase A (EC 3.4.24.24) precursor - rat
Length = 708
Score = 517 bits (1318), Expect = e-145
Identities = 246/424 (58%), Positives = 301/424 (70%), Gaps = 9/424 (2%)
Query: 35 IKFPGDVAPK--TDKELAVQYLNTFYGCPKESCNLFV---LKDTLKKMQKFFGLPQTGDL 89
+ FP D+ TD +LA YL YG + + + L+ L +QK LPQTG+L
Sbjct: 29 VVFPRDLKTSNLTDTQLAEDYLYR-YGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGEL 87
Query: 90 DQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQ 149
D T++ +R PRCG PDV + F KW + ITY I YT DL + +DD+FARAF
Sbjct: 88 DSETLKAIRSPRCGVPDVGKFQTFDGDLKWHHHNITYWIQNYTEDLPRDVIDDSFARAFA 147
Query: 150 VWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDD 209
VWS VTPL F+R++ EADI+I FG EHGDGYPFDGKDGLLAHAF PG G+ GD+HFDD
Sbjct: 148 VWSAVTPLTFTRVYGLEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDD 207
Query: 210 DELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDG 269
DELW+LG+G VV +GNA+G C FPF F G+ Y SCT GR+DG WC TT +++ D
Sbjct: 208 DELWSLGKGAVVPTYFGNANGAPCHFPFTFEGRSYLSCTTDGRNDGKPWCGTTADYDTDR 267
Query: 270 KYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKY 329
KYGFCP E L+T GN +G+PC FPF F+G SY +CTT+GR+DGYRWC TT +YD+DK
Sbjct: 268 KYGFCPSENLYTEHGNGDGKPCVFPFIFEGHSYSACTTKGRSDGYRWCATTANYDQDKAD 327
Query: 330 GFCPETAMSTV-GGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWG 388
GFCP A TV GGNS G CVFPF FLG +Y +CTS GRSDG++WCATT+N+D D+KWG
Sbjct: 328 GFCPTRADVTVTGGNSAGEMCVFPFVFLGKQYSTCTSEGRSDGRLWCATTSNFDADKKWG 387
Query: 389 FCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELY--G 446
FCPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y Y ++ L +DDIKGI LY G
Sbjct: 388 FCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYHYHEDSPLHEDDIKGIHHLYGRG 447
Query: 447 ASPD 450
+ PD
Sbjct: 448 SKPD 451
Score = 82.3 bits (200), Expect = 2e-14
Identities = 49/173 (28%), Positives = 85/173 (48%), Gaps = 7/173 (4%)
Query: 469 CKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPM-GPLLVATFWPELPEKIDAVYEAP 527
C D VFD IA I+G + FFKD W+ + GP L+A WP P K+++ +E P
Sbjct: 519 CNVD-VFDAIADIQGALHFFKDGRYWKFSNHGGNQLQGPFLIARTWPAFPSKLNSAFEDP 577
Query: 528 QEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDK 587
Q +K FF + W+Y+ ++ P+ L LGL +V V + K + + ++
Sbjct: 578 QPKKIFFFLWAQMWVYTGQSVLG--PRSLDKLGLGSEVTLVTGLLP-RRGGKALLISRER 634
Query: 588 FWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKL 640
W+++ +K+DP + + ++ +P N V Q +YF Y+ ++
Sbjct: 635 IWKFDLKSQKVDPQSVTRLDNEFSGVPWNSHNVFQYQ--DKAYFCHDKYFWRV 685
>sp|P50282|COG9_RAT 92 KDA TYPE IV COLLAGENASE PRECURSOR (92 KDA GELATINASE) (MATRIX
METALLOPROTEINASE-9) (MMP-9) (GELATINASE B) (GELB)
pir||S72371 collagenase type IV, 92K, precursor - rat
gb|AAB01721.1| (U36476) 92-kDa type IV collagenase [Rattus norvegicus]
Length = 708
Score = 517 bits (1318), Expect = e-145
Identities = 246/424 (58%), Positives = 301/424 (70%), Gaps = 9/424 (2%)
Query: 35 IKFPGDVAPK--TDKELAVQYLNTFYGCPKESCNLFV---LKDTLKKMQKFFGLPQTGDL 89
+ FP D+ TD +LA YL YG + + + L+ L +QK LPQTG+L
Sbjct: 29 VVFPRDLKTSNLTDTQLAEDYLYR-YGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGEL 87
Query: 90 DQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQ 149
D T++ +R PRCG PDV + F KW + ITY I YT DL + +DD+FARAF
Sbjct: 88 DSETLKAIRSPRCGVPDVGKFQTFDGDLKWHHHNITYWIQSYTEDLPRDVIDDSFARAFA 147
Query: 150 VWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDD 209
VWS VTPL F+R++ EADI+I FG EHGDGYPFDGKDGLLAHAF PG G+ GD+HFDD
Sbjct: 148 VWSAVTPLTFTRVYGLEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDD 207
Query: 210 DELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDG 269
DELW+LG+G VV +GNA+G C FPF F G+ Y SCT GR+DG WC TT +++ D
Sbjct: 208 DELWSLGKGAVVPTYFGNANGAPCHFPFTFEGRSYLSCTTDGRNDGKPWCGTTADYDTDR 267
Query: 270 KYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKY 329
KYGFCP E L+T GN +G+PC FPF F+G SY +CTT+GR+DGYRWC TT +YD+DK
Sbjct: 268 KYGFCPSENLYTEHGNGDGKPCVFPFIFEGHSYSACTTKGRSDGYRWCATTANYDQDKAD 327
Query: 330 GFCPETAMSTV-GGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWG 388
GFCP A TV GGNS G CVFPF FLG +Y +CTS GRSDG++WCATT+N+D D+KWG
Sbjct: 328 GFCPTRADVTVTGGNSAGEMCVFPFVFLGKQYSTCTSEGRSDGRLWCATTSNFDADKKWG 387
Query: 389 FCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELY--G 446
FCPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y Y ++ L +DDIKGI LY G
Sbjct: 388 FCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYHYHEDSPLHEDDIKGIHHLYGRG 447
Query: 447 ASPD 450
+ PD
Sbjct: 448 SKPD 451
Score = 82.3 bits (200), Expect = 2e-14
Identities = 49/173 (28%), Positives = 85/173 (48%), Gaps = 7/173 (4%)
Query: 469 CKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPM-GPLLVATFWPELPEKIDAVYEAP 527
C D VFD IA I+G + FFKD W+ + GP L+A WP P K+++ +E P
Sbjct: 519 CNVD-VFDAIADIQGALHFFKDGRYWKFSNHGGNQLQGPFLIARTWPAFPSKLNSAFEDP 577
Query: 528 QEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDK 587
Q +K FF + W+Y+ ++ P+ L LGL +V V + K + + ++
Sbjct: 578 QPKKIFFFLWAQMWVYTGQSVLG--PRSLDKLGLGSEVTLVTGLLP-RRGGKALLISRER 634
Query: 588 FWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKL 640
W+++ +K+DP + + ++ +P N V Q +YF Y+ ++
Sbjct: 635 IWKFDLKSQKVDPQSVTRLDNEFSGVPWNSHNVFQYQ--DKAYFCHDKYFWRV 685
>emb|CAA51315.1| (X72795) gelatinase b [Mus musculus]
Length = 598
Score = 467 bits (1190), Expect = e-130
Identities = 206/316 (65%), Positives = 250/316 (78%), Gaps = 3/316 (0%)
Query: 138 ETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAP 197
+ +DDAFARAF VW +V PL F+R++ EADI+I FG EHGDGYPFDGKDGLLAHAF P
Sbjct: 3 DMIDDAFARAFAVWGEVAPLTFTRVYGPEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPP 62
Query: 198 GTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFL 257
G GV GD+HFDDDELW+LG+G V+ YGN++G C FPF F G+ Y++CT GR+DG
Sbjct: 63 GAGVQGDAHFDDDELWSLGKGVVIPTYYGNSNGAPCHFPFTFEGRSYSACTTDGRNDGTP 122
Query: 258 WCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWC 317
WCSTT +++KDGK+GFCP E L+T GN EG+PC FPF F+G SY +CTT+GR+DGYRWC
Sbjct: 123 WCSTTADYDKDGKFGFCPSERLYTEHGNGEGKPCVFPFIFEGRSYSACTTKGRSDGYRWC 182
Query: 318 GTTEDYDRDKKYGFCPETAMST-VGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCA 376
TT +YD+DK YGFCP +T VGGNS G CVFPF FLG +Y SCTS GR DG++WCA
Sbjct: 183 ATTANYDQDKLYGFCPTRVDATVVGGNSAGELCVFPFVFLGKQYSSCTSDGRRDGRLWCA 242
Query: 377 TTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQD 436
TT+N+D D+KWGFCPDQGYSLFLVAAHEFGHA+GL+HS P ALM P+Y+Y + F L++D
Sbjct: 243 TTSNFDTDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPLYSYLEGFPLNKD 302
Query: 437 DIKGIQELY--GASPD 450
DI GIQ LY G+ PD
Sbjct: 303 DIDGIQYLYGRGSKPD 318
Score = 102 bits (253), Expect = 9e-21
Identities = 56/177 (31%), Positives = 94/177 (52%), Gaps = 7/177 (3%)
Query: 469 CKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPM-GPLLVATFWPELPEKIDAVYEAP 527
C D VFD IA+I+G + FFKD + W+ + R P+ GP L A WP LP +D+ +E P
Sbjct: 402 CNVD-VFDAIAEIQGALHFFKDGWYWKFLNHRGSPLQGPFLTARTWPALPATLDSAFEDP 460
Query: 528 QEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDK 587
Q ++ FF+G + W+Y+ T+ P+ L LGL P+V V + K +F+ +
Sbjct: 461 QTKRVFFFSGRQMWVYTGKTVLG--PRSLDKLGLGPEVTHVSGLLP-RRPGKALLFSKGR 517
Query: 588 FWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQS 644
WR++ +K+DP + ++ +P N + Q +YF G ++ ++ Q+
Sbjct: 518 VWRFDLKSQKVDPQSVIRVDKEFSGVPWNSHDIFQYQ--DKAYFCHGKFFWRVSFQN 572
>pdb|1GEN| C-Terminal Domain Of Gelatinase A
Length = 218
Score = 430 bits (1095), Expect = e-119
Identities = 204/218 (93%), Positives = 204/218 (93%)
Query: 443 ELYGASPDIDXXXXXXXXXXXXXXEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDK 502
ELYGASPDID EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDK
Sbjct: 1 ELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDK 60
Query: 503 PMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLP 562
PMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLP
Sbjct: 61 PMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLP 120
Query: 563 PDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVD 622
PDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVD
Sbjct: 121 PDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVD 180
Query: 623 LQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
LQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
Sbjct: 181 LQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 218
>pdb|1RTG| C-Terminal Domain (Haemopexin-Like Domain) Of Human Matrix
Metalloproteinase-2
Length = 210
Score = 415 bits (1056), Expect = e-115
Identities = 194/194 (100%), Positives = 194/194 (100%)
Query: 467 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA 526
EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA
Sbjct: 17 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA 76
Query: 527 PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD 586
PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD
Sbjct: 77 PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD 136
Query: 587 KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK 646
KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK
Sbjct: 137 KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK 196
Query: 647 SVKFGSIKSDWLGC 660
SVKFGSIKSDWLGC
Sbjct: 197 SVKFGSIKSDWLGC 210
Score = 33.6 bits (75), Expect = 7.1
Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
Query: 555 PLTSLG-LPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAI 613
P +LG + P++ + D F+ + IF + + V + P P L+A W +
Sbjct: 7 PTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPEL 66
Query: 614 PDNLDAVVDLQGGGHSYFFKGAYY 637
P+ +DAV + + FF G Y
Sbjct: 67 PEKIDAVYEAPQEEKAVFFAGNEY 90
>dbj|BAA96389.1| (AB043996) MMP-9 [Bos taurus]
Length = 324
Score = 342 bits (869), Expect = 6e-93
Identities = 156/297 (52%), Positives = 208/297 (69%), Gaps = 3/297 (1%)
Query: 34 IIKFPGDVAPK-TDKELAVQYLNTFYGCP--KESCNLFVLKDTLKKMQKFFGLPQTGDLD 90
++ FPG+ T+++LA +YL + P + S + L+ L + Q+ LP+TG+LD
Sbjct: 28 VVVFPGEPRTNLTNRQLAEEYLYRYGYTPGAELSEDGQSLQRALLRFQRRLSLPETGELD 87
Query: 91 QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQV 150
T+ MR PRCG PDV + F + KW + ITY I Y+ DL +DDAFARAF +
Sbjct: 88 STTLNAMRAPRCGVPDVGRFQTFEGELKWHHHNITYWIQNYSEDLPRAVIDDAFARAFAL 147
Query: 151 WSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD 210
WS VTPL F+R++ EADI+I FG EHGDGYPFDGK+GLLAHAF PG G+ GD+HFDD+
Sbjct: 148 WSAVTPLTFTRVYGPEADIVIQFGVREHGDGYPFDGKNGLLAHAFPPGKGIQGDAHFDDE 207
Query: 211 ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK 270
+LW+LG+G V+ +GNA G C FPF F G+ Y++CT GRSD LWCSTT +++ D +
Sbjct: 208 KLWSLGKGVVIPTYFGNAKGAACHFPFTFEGRSYSACTTDGRSDDMLWCSTTADYDADRQ 267
Query: 271 YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDK 327
+GFCP E L+T GNA+G+PC FPF FQG +Y +CT++GR+DGYRWC TT +YDRDK
Sbjct: 268 FGFCPSERLYTQDGNADGKPCVFPFTFQGRTYSACTSDGRSDGYRWCATTANYDRDK 324
Score = 152 bits (379), Expect = 2e-35
Identities = 63/105 (60%), Positives = 76/105 (72%)
Query: 281 TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTV 340
T GNA+G C FPF F+G SY +CTT+GR+D WC TT DYD D+++GFCP + T
Sbjct: 220 TYFGNAKGAACHFPFTFEGRSYSACTTDGRSDDMLWCSTTADYDADRQFGFCPSERLYTQ 279
Query: 341 GGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDR 385
GN++G PCVFPFTF G Y +CTS GRSDG WCATTANYD D+
Sbjct: 280 DGNADGKPCVFPFTFQGRTYSACTSDGRSDGYRWCATTANYDRDK 324
Score = 83.5 bits (203), Expect = 7e-15
Identities = 34/71 (47%), Positives = 48/71 (66%)
Query: 323 YDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYD 382
+D +K + + T GN++GA C FPFTF G Y +CT+ GRSD +WC+TTA+YD
Sbjct: 204 FDDEKLWSLGKGVVIPTYFGNAKGAACHFPFTFEGRSYSACTTDGRSDDMLWCSTTADYD 263
Query: 383 DDRKWGFCPDQ 393
DR++GFCP +
Sbjct: 264 ADRQFGFCPSE 274
>dbj|BAA96387.1| (AB043994) MMP-2 [Bos taurus]
Length = 162
Score = 342 bits (868), Expect = 7e-93
Identities = 158/162 (97%), Positives = 160/162 (98%)
Query: 499 PRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTS 558
PRDKPMGPLLVATFWPELPEKIDAVYE PQEEKAVFFAGNEYW+YSASTLERGYPKPLTS
Sbjct: 1 PRDKPMGPLLVATFWPELPEKIDAVYEDPQEEKAVFFAGNEYWVYSASTLERGYPKPLTS 60
Query: 559 LGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLD 618
LGLPP VQ+VDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLD
Sbjct: 61 LGLPPGVQKVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLD 120
Query: 619 AVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
AVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
Sbjct: 121 AVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 162
>gb|AAD26635.1| (AF111100) matrix metalloproteinase-2 precursor [Canis familiaris]
Length = 152
Score = 332 bits (842), Expect = 8e-90
Identities = 149/152 (98%), Positives = 150/152 (98%)
Query: 120 DKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHG 179
DKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHG
Sbjct: 1 DKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHG 60
Query: 180 DGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLF 239
DGYPFDGKDGLLAHAFAPG GVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLF
Sbjct: 61 DGYPFDGKDGLLAHAFAPGPGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLF 120
Query: 240 NGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKY 271
NG+EY SCTDTGRSDGFLWCSTTYNFEKDGKY
Sbjct: 121 NGREYTSCTDTGRSDGFLWCSTTYNFEKDGKY 152
Score = 68.3 bits (164), Expect = 3e-10
Identities = 26/46 (56%), Positives = 34/46 (73%)
Query: 284 GNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKY 329
GNA+G+ CKFPF F G Y SCT GR+DG+ WC TT ++++D KY
Sbjct: 107 GNADGEYCKFPFLFNGREYTSCTDTGRSDGFLWCSTTYNFEKDGKY 152
Score = 64.4 bits (154), Expect = 4e-09
Identities = 28/70 (40%), Positives = 40/70 (57%)
Query: 318 GTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCAT 377
G +D D+ + + GN++G C FPF F G +Y SCT GRSDG +WC+T
Sbjct: 83 GGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGREYTSCTDTGRSDGFLWCST 142
Query: 378 TANYDDDRKW 387
T N++ D K+
Sbjct: 143 TYNFEKDGKY 152
>gb|AAD30283.1| (AF135231) MMP-2 protein [Bos taurus]
Length = 153
Score = 324 bits (821), Expect = 2e-87
Identities = 145/151 (96%), Positives = 147/151 (97%)
Query: 121 KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD 180
K QITYRIIGYTPDLDP+TVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
Sbjct: 1 KEQITYRIIGYTPDLDPQTVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD 60
Query: 181 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN 240
GYPFDGKDGLLAHAFAPG GVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPF FN
Sbjct: 61 GYPFDGKDGLLAHAFAPGPGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFRFN 120
Query: 241 GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKY 271
GKEY SCTDTGRSDGFLWCSTTYNF+KDGKY
Sbjct: 121 GKEYTSCTDTGRSDGFLWCSTTYNFDKDGKY 151
Score = 72.6 bits (175), Expect = 1e-11
Identities = 28/46 (60%), Positives = 35/46 (75%)
Query: 284 GNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKY 329
GNA+G+ CKFPFRF G Y SCT GR+DG+ WC TT ++D+D KY
Sbjct: 106 GNADGEYCKFPFRFNGKEYTSCTDTGRSDGFLWCSTTYNFDKDGKY 151
Score = 66.0 bits (158), Expect = 1e-09
Identities = 29/70 (41%), Positives = 40/70 (56%)
Query: 318 GTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCAT 377
G +D D+ + + GN++G C FPF F G +Y SCT GRSDG +WC+T
Sbjct: 82 GGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFRFNGKEYTSCTDTGRSDGFLWCST 141
Query: 378 TANYDDDRKW 387
T N+D D K+
Sbjct: 142 TYNFDKDGKY 151
>gb|AAD27837.1|AF123396_1 (AF123396) gelatinase B [Canis familiaris]
Length = 208
Score = 285 bits (721), Expect = 1e-75
Identities = 126/207 (60%), Positives = 155/207 (74%), Gaps = 4/207 (1%)
Query: 154 VTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELW 213
VTPL F+R++ EADI+I FG EHGDGYPFDGK+GLLAHAF PG G+ GD+HFDD+ELW
Sbjct: 2 VTPLTFTRVYGPEADIIIQFGVREHGDGYPFDGKNGLLAHAFPPGPGIQGDAHFDDEELW 61
Query: 214 TLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGF 273
TLG+G VV +GNADG C FPF F G+ Y++CT GRSD WCSTT +++ D ++GF
Sbjct: 62 TLGKGVVVPTHFGNADGAPCHFPFTFEGRSYSACTTDGRSDDTPWCSTTADYDTDRRFGF 121
Query: 274 CPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCP 333
CP E L+T GN +G+PC FPF F+G SY +CTT+GR+DGYRWC TT DYD+DK YGF P
Sbjct: 122 CPSEKLYTQDGNGDGKPCVFPFTFEGRSYSTCTTDGRSDGYRWCSTTGDYDQDKLYGFWP 181
Query: 334 ETAMSTVGGNSE---GAPCVFPFTFLG 357
T + G + G+PCVFPF FLG
Sbjct: 182 -TRVEFRGDRGQLPPGSPCVFPFIFLG 207
Score = 157 bits (392), Expect = 5e-37
Identities = 66/124 (53%), Positives = 84/124 (67%), Gaps = 9/124 (7%)
Query: 277 EALFTMG---------GNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDK 327
E L+T+G GNA+G PC FPF F+G SY +CTT+GR+D WC TT DYD D+
Sbjct: 58 EELWTLGKGVVVPTHFGNADGAPCHFPFTFEGRSYSACTTDGRSDDTPWCSTTADYDTDR 117
Query: 328 KYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKW 387
++GFCP + T GN +G PCVFPFTF G Y +CT+ GRSDG WC+TT +YD D+ +
Sbjct: 118 RFGFCPSEKLYTQDGNGDGKPCVFPFTFEGRSYSTCTTDGRSDGYRWCSTTGDYDQDKLY 177
Query: 388 GFCP 391
GF P
Sbjct: 178 GFWP 181
Score = 83.1 bits (202), Expect = 9e-15
Identities = 34/71 (47%), Positives = 48/71 (66%)
Query: 323 YDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYD 382
+D ++ + + T GN++GAPC FPFTF G Y +CT+ GRSD WC+TTA+YD
Sbjct: 55 FDDEELWTLGKGVVVPTHFGNADGAPCHFPFTFEGRSYSACTTDGRSDDTPWCSTTADYD 114
Query: 383 DDRKWGFCPDQ 393
DR++GFCP +
Sbjct: 115 TDRRFGFCPSE 125
>emb|CAA09079.1| (AJ010314) matrix metalloproteinase-2 [Equus caballus]
Length = 114
Score = 244 bits (616), Expect = 3e-63
Identities = 110/114 (96%), Positives = 112/114 (97%)
Query: 116 KPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGR 175
KPKW+K QITYRIIGYTPDLDPETVDDAFARAF+VWSDVTPLRFSRIHDGEADIMINFGR
Sbjct: 1 KPKWEKTQITYRIIGYTPDLDPETVDDAFARAFRVWSDVTPLRFSRIHDGEADIMINFGR 60
Query: 176 WEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNAD 229
WEHGDGYPFDGKDGLLAHAFAPG GVGGDSHFDDDELWTLGEGQVVRVKYGNAD
Sbjct: 61 WEHGDGYPFDGKDGLLAHAFAPGPGVGGDSHFDDDELWTLGEGQVVRVKYGNAD 114
>pdb|1QIB|A Chain A, Crystal Structure Of Gelatinase A Catalytic Domain
Length = 161
Score = 229 bits (577), Expect = 1e-58
Identities = 102/104 (98%), Positives = 104/104 (99%)
Query: 115 RKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFG 174
RKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFG
Sbjct: 1 RKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFG 60
Query: 175 RWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEG 218
RWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELW+LG+G
Sbjct: 61 RWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWSLGKG 104
Score = 129 bits (321), Expect = 1e-28
Identities = 60/71 (84%), Positives = 63/71 (88%)
Query: 379 ANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDI 438
+++DDD W GYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDI
Sbjct: 91 SHFDDDELWSLGKGVGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDI 150
Query: 439 KGIQELYGASP 449
KGIQELYGASP
Sbjct: 151 KGIQELYGASP 161
>sp|P07152|COGX_RAT STROMELYSIN-2 PRECURSOR (MATRIX METALLOPROTEINASE-10) (MMP-10)
(TRANSIN-2) (SL-2) (TRANSFORMATION-ASSOCIATED PROTEIN
34A)
pir||KCRTS2 stromelysin 2 (EC 3.4.24.22) precursor - rat
emb|CAA28739.1| (X05083) transin-2 (AA 1-476) [Rattus norvegicus]
gb|AAA42202.1| (M65253) transformation-associated protein [Rattus norvegicus]
Length = 476
Score = 224 bits (564), Expect = 3e-57
Identities = 118/287 (41%), Positives = 166/287 (57%), Gaps = 10/287 (3%)
Query: 379 ANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTK---NFRLSQ 435
A++DDD KW P G +LFLVAAHE GH++GL HS + +LM P+Y ++ N RLSQ
Sbjct: 195 AHFDDDEKWSLGPS-GTNLFLVAAHELGHSLGLFHSNNKESLMYPVYRFSTSQANIRLSQ 253
Query: 436 DDIKGIQELYGASPDIDXXXXXXXXXXXXXXEICKQD--IVFDGIAQIRGEIFFFKDRFI 493
DDI+GIQ LYGA P D K D + FD + +RGE FFKDR
Sbjct: 254 DDIEGIQSLYGARPSSDATVVPVPSVSPKPETPVKCDPALSFDAVTMLRGEFLFFKDRHF 313
Query: 494 WRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYP 553
WR +P L+ A FWP LP +DA YEA +++ + F G+++W + ++ GYP
Sbjct: 314 WRRTQWNPEPEFHLISA-FWPSLPSGLDAAYEANNKDRVLIFKGSQFWAVRGNEVQAGYP 372
Query: 554 KPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAI 613
K + +LG PP V+++DAA + KKTY F GDK+WR++E ++ MD GFP+LI D + I
Sbjct: 373 KRIHTLGFPPTVKKIDAAVFEKEKKKTYFFVGDKYWRFDETRQLMDKGFPRLITDDFPGI 432
Query: 614 PDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
+DAV L G YFF G+ + + + ++V + WL C
Sbjct: 433 EPQVDAV--LHAFGFFYFFCGSSQFEFD-PNARTVTHTLKSNSWLLC 476
Score = 203 bits (510), Expect = 7e-51
Identities = 98/175 (56%), Positives = 117/175 (66%), Gaps = 6/175 (3%)
Query: 48 ELAVQYLNTFYGCPKESCNLFVLKDT------LKKMQKFFGLPQTGDLDQNTIETMRKPR 101
+LA QYL +Y K F KD+ +++MQKF GL TG LD NT+E M KPR
Sbjct: 32 DLAQQYLEKYYNFRKNEKQFFKRKDSSPVVKKIEEMQKFLGLEMTGKLDSNTVEMMHKPR 91
Query: 102 CGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSR 161
CG PDV ++ FP PKW KN I+YRI+ YT DL E+VD A RA +VW +VTPL FSR
Sbjct: 92 CGVPDVGGFSTFPGSPKWRKNHISYRIVNYTLDLPRESVDSAIERALKVWEEVTPLTFSR 151
Query: 162 IHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLG 216
I +GEADIMI+F EHGD YPFDG LAHA+ PG G GD+HFDDDE W+LG
Sbjct: 152 ISEGEADIMISFAVGEHGDFYPFDGVGQSLAHAYPPGPGFYGDAHFDDDEKWSLG 206
>ref|NP_062344.1| matrix metalloproteinase 10; stromelysin 2 [Mus musculus]
pir||JC6505 stromelysin 2 (EC 3.4.24.22) precursor - mouse
emb|CAA73641.1| (Y13185) stromelysin 2 [Mus musculus]
Length = 476
Score = 221 bits (557), Expect = 2e-56
Identities = 115/286 (40%), Positives = 164/286 (57%), Gaps = 10/286 (3%)
Query: 380 NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTK---NFRLSQD 436
++DDD KW P G +LFLVAAHE GH++GL HS +LM P+Y ++ NF LSQD
Sbjct: 196 HFDDDEKWTLAPS-GTNLFLVAAHELGHSLGLFHSDKKESLMYPVYRFSTSPANFHLSQD 254
Query: 437 DIKGIQELYGASPDIDXXXXXXXXXXXX--XXEICKQDIVFDGIAQIRGEIFFFKDRFIW 494
DI+GIQ LYGA P D + C + FD ++ +RGE+ FFKDR+ W
Sbjct: 255 DIEGIQSLYGAGPSSDATVVPVLSVSPRPETPDKCDPALSFDSVSTLRGEVLFFKDRYFW 314
Query: 495 RTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPK 554
R +P L+ A FWP LP +DA YEA + + F G+++W + ++ GYPK
Sbjct: 315 RRSHWNPEPEFHLISA-FWPTLPSDLDAAYEAHNTDSVLIFKGSQFWAVRGNEVQAGYPK 373
Query: 555 PLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIP 614
+ +LG PP V+++DAA + KKTY F GDK+WR++E + MD GFP+ I D + I
Sbjct: 374 GIHTLGFPPTVKKIDAAVFEKEKKKTYFFVGDKYWRFDETRHVMDKGFPRQITDDFPGIE 433
Query: 615 DNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
+DAV L G YFF+G+ + + + ++V + WL C
Sbjct: 434 PQVDAV--LHEFGFFYFFRGSSQFEFD-PNARTVTHILKSNSWLLC 476
Score = 203 bits (510), Expect = 7e-51
Identities = 97/174 (55%), Positives = 117/174 (66%), Gaps = 6/174 (3%)
Query: 48 ELAVQYLNTFYGCPKESCNLFVLKDT------LKKMQKFFGLPQTGDLDQNTIETMRKPR 101
+LA QYL +Y K +F KD+ +++MQKF GL TG LD NT+E M KPR
Sbjct: 32 DLAQQYLEKYYNFKKNEKQIFKRKDSSPVVKKIQEMQKFLGLEMTGKLDSNTMELMHKPR 91
Query: 102 CGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSR 161
CG PDV ++ FP PKW K+ ITYRI+ YTPDL ++VD A +A +VW +VTPL FSR
Sbjct: 92 CGVPDVGGFSTFPGSPKWRKSHITYRIVNYTPDLPRQSVDSAIEKALKVWEEVTPLTFSR 151
Query: 162 IHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTL 215
I +GEADIMI+F EHGD YPFDG LAHA+ PG G GD HFDDDE WTL
Sbjct: 152 ISEGEADIMISFAVGEHGDFYPFDGPGQSLAHAYPPGPGFYGDVHFDDDEKWTL 205
>gb|AAC34604.1| (AF070478) matrix metalloproteinase-13 [Gallus gallus]
Length = 378
Score = 219 bits (551), Expect = 1e-55
Identities = 114/258 (44%), Positives = 154/258 (59%), Gaps = 12/258 (4%)
Query: 379 ANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYT--KNFRLSQD 436
A++DDD W +GY+LFLVAAHEFGH++GLEHS+DPGALM PIYTYT F L D
Sbjct: 106 AHFDDDETWSD-DSRGYNLFLVAAHEFGHSLGLEHSRDPGALMFPIYTYTGKSGFVLPDD 164
Query: 437 DIKGIQELYGASPDIDXXXXXXXXXXXXXXEICKQDIVFDGIAQIRGEIFFFKDRFIWRT 496
D++GIQELYGA D D E C D+ D I ++RGE+ FKDRF WR
Sbjct: 165 DVQGIQELYGAG-DRDPNPKHPKTP-----EKCAADLSIDAITKLRGEMLVFKDRFFWR- 217
Query: 497 VTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPL 556
+ P+ +L+ +FWPELP KIDA YE P ++ F G + W + + G+PK +
Sbjct: 218 LHPQMVEAELVLIKSFWPELPNKIDAAYENPIKDLVFMFKGKKVWAMNGYDIVEGFPKKI 277
Query: 557 TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDN 616
+G P +++++DA + KT F G+K+W Y+E + MD G+PK I D + I D
Sbjct: 278 YEMGFPKEMKKIDAVVHIDDTGKTLFFTGNKYWSYDEETEVMDTGYPKFIEDEFAGIGDR 337
Query: 617 LDAVVDLQGGGHSYFFKG 634
+DAV G+ YFF G
Sbjct: 338 VDAV--YHRNGYLYFFNG 353
Score = 168 bits (421), Expect = 2e-40
Identities = 76/115 (66%), Positives = 84/115 (72%)
Query: 100 PRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRF 159
PRCG PDV Y FFPRK KW +TYRI+ YT DL V+ AF RAF+VWSDVTPL F
Sbjct: 1 PRCGVPDVGEYKFFPRKLKWSNTNLTYRIMSYTSDLRRAEVERAFKRAFKVWSDVTPLNF 60
Query: 160 SRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWT 214
+RI G ADIMI+FG EHGD YPFDG GLLAHAF PG GGD+HFDDDE W+
Sbjct: 61 TRIRSGTADIMISFGTKEHGDFYPFDGPSGLLAHAFPPGPDYGGDAHFDDDETWS 115
>gb|AAF17559.1|AF201729_1 (AF201729) matrix metalloproteinase-13 [Canis familiaris]
Length = 452
Score = 217 bits (546), Expect = 4e-55
Identities = 105/181 (58%), Positives = 125/181 (69%), Gaps = 7/181 (3%)
Query: 40 DVAPKTDKELAVQYLNTFY------GCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNT 93
D + D +LA +YL ++Y G K+S V D L++MQ FFGL TG LD NT
Sbjct: 21 DDLSEEDFQLAERYLKSYYYPLNPAGILKKSAAGSVA-DRLREMQSFFGLEVTGKLDDNT 79
Query: 94 IETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSD 153
++ M+KPRCG PDV YN FPR KW K +TYRI+ YTPDL V+ AF +AF+VWSD
Sbjct: 80 LDIMKKPRCGVPDVGEYNVFPRTLKWSKTNLTYRIVNYTPDLTHSEVEKAFKKAFKVWSD 139
Query: 154 VTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELW 213
VTPL F+R+HDG ADIMI+FG EHGD YPFDG GLLAHAF PG GGD+HFDDDE W
Sbjct: 140 VTPLNFTRLHDGTADIMISFGTKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETW 199
Query: 214 T 214
T
Sbjct: 200 T 200
Score = 210 bits (529), Expect = 4e-53
Identities = 105/258 (40%), Positives = 150/258 (57%), Gaps = 12/258 (4%)
Query: 379 ANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYT--KNFRLSQD 436
A++DDD W +GY+LFLVAAHEFGH++GL+HS+DPGALM PIYTYT +F L D
Sbjct: 191 AHFDDDETWT-SSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDD 249
Query: 437 DIKGIQELYGASPDIDXXXXXXXXXXXXXXEICKQDIVFDGIAQIRGEIFFFKDRFIWRT 496
D++GIQ LYG + + C + D I +RGE FKDRF WR
Sbjct: 250 DVQGIQSLYGPGDE------DPNPRHPKTPDKCDPSLSLDAITSLRGETMIFKDRFFWR- 302
Query: 497 VTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPL 556
+ P+ L +FWPELP +IDA YE P + F G +YW + + GYP+ +
Sbjct: 303 LHPQQVDAELFLTKSFWPELPNRIDAAYEHPSRDLIFIFRGRKYWALNGYDILEGYPQKI 362
Query: 557 TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDN 616
+ LG P +V+++ AA ++ KT F+G++ W Y++ + MD +P+LI + + I D
Sbjct: 363 SELGFPKEVKKISAAVHFEDTGKTLFFSGNQVWSYDDTNQIMDKDYPRLIEEDFPGIGDK 422
Query: 617 LDAVVDLQGGGHSYFFKG 634
+DAV + G+ YFF G
Sbjct: 423 VDAV--YEKNGYIYFFNG 438
>sp|P28053|COG1_BOVIN INTERSTITIAL COLLAGENASE PRECURSOR (MATRIX METALLOPROTEINASE-1)
(MMP-1) (FIBROBLAST COLLAGENASE)
pir||KCBOI interstitial collagenase (EC 3.4.24.7) precursor - bovine
emb|CAA41210.1| (X58256) preprocollagenase [Bos taurus]
Length = 469
Score = 214 bits (540), Expect = 2e-54
Identities = 116/283 (40%), Positives = 159/283 (55%), Gaps = 12/283 (4%)
Query: 379 ANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDI 438
A++DDD +W Q Y+L+ VAAHEFGH++GL HS D GALM P YT++ + +LSQDDI
Sbjct: 195 AHFDDD-EWWTSNFQDYNLYRVAAHEFGHSLGLAHSTDIGALMYPSYTFSGDVQLSQDDI 253
Query: 439 KGIQELYGASPDIDXXXXXXXXXXXXXXEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVT 498
GIQ +YG S + E+C + FD I IRGE+ FFKDRF RT
Sbjct: 254 DGIQAIYGPSQN------PTQPVGPQTPEVCDSKLTFDAITTIRGEVMFFKDRFYMRT-N 306
Query: 499 PRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPL-T 557
P + ++ FWP+LP + A YE ++ FF GN+YW + RGYP+ +
Sbjct: 307 PLYPEVELNFISVFWPQLPNGLQAAYEVADRDEVRFFKGNKYWAVKGQDVLRGYPRDIYR 366
Query: 558 SLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNL 617
S G P V+ +DAA + KTY F +K WRY+E K+ MD G+PK+IA+ + I + +
Sbjct: 367 SFGFPRTVKSIDAAVSEEDTGKTYFFVANKCWRYDEYKQSMDAGYPKMIAEDFPGIGNKV 426
Query: 618 DAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
DAV Q GG YFF G K + Q+ + + S W C
Sbjct: 427 DAV--FQKGGFFYFFHGRRQYKFDPQTKRILTLLKANS-WFNC 466
Score = 181 bits (455), Expect = 2e-44
Identities = 87/175 (49%), Positives = 112/175 (63%), Gaps = 6/175 (3%)
Query: 46 DKELAVQYLNTFYGCP------KESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRK 99
D E +YL +Y + N ++ + LK+MQKFFGL TG D T+ M++
Sbjct: 30 DVETVKKYLENYYNLNSNGKKVERQRNGGLITEKLKQMQKFFGLRVTGKPDAETLNVMKQ 89
Query: 100 PRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRF 159
PRCG PDVA + P K W+ +TYRI YTPDL VD A +AFQ+WS+VTPL F
Sbjct: 90 PRCGVPDVAPFVLTPGKSCWENTNLTYRIENYTPDLSRADVDQAIEKAFQLWSNVTPLTF 149
Query: 160 SRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWT 214
+++ +G+ADIMI+F R +H D PFDG G LAHAF PG G+GGD+HFDDDE WT
Sbjct: 150 TKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGAGIGGDAHFDDDEWWT 204
>ref|NP_002418.1| matrix metalloproteinase 13 (collagenase 3) [Homo sapiens]
sp|P45452|COGZ_HUMAN COLLAGENASE 3 PRECURSOR (MATRIX METALLOPROTEINASE-13) (MMP-13)
pir||A53711 collagenase 3 (EC 3.4.24.-) - human
emb|CAA53056.1| (X75308) collagenase 3 [Homo sapiens]
emb|CAA57108.1| (X81334) collagenase-3 [Homo sapiens]
Length = 471
Score = 214 bits (539), Expect = 3e-54
Identities = 107/258 (41%), Positives = 152/258 (58%), Gaps = 12/258 (4%)
Query: 379 ANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYT--KNFRLSQD 436
A++DDD W +GY+LFLVAAHEFGH++GL+HS+DPGALM PIYTYT +F L D
Sbjct: 199 AHFDDDETWT-SSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDD 257
Query: 437 DIKGIQELYGASPDIDXXXXXXXXXXXXXXEICKQDIVFDGIAQIRGEIFFFKDRFIWRT 496
D++GIQ LYG + + C + D I +RGE FKDRF WR
Sbjct: 258 DVQGIQSLYGPGDE------DPNPKHPKTPDKCDPSLSLDAITSLRGETMIFKDRFFWR- 310
Query: 497 VTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPL 556
+ P+ L +FWPELP +IDA YE P + F G ++W + + GYPK +
Sbjct: 311 LHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKI 370
Query: 557 TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDN 616
+ LGLP +V+++ AA ++ KT +F+G++ WRY++ MD +P+LI + + I D
Sbjct: 371 SELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLIEEDFPGIGDK 430
Query: 617 LDAVVDLQGGGHSYFFKG 634
+DAV + G+ YFF G
Sbjct: 431 VDAV--YEKNGYIYFFNG 446
Score = 212 bits (534), Expect = 1e-53
Identities = 101/181 (55%), Positives = 124/181 (67%), Gaps = 7/181 (3%)
Query: 40 DVAPKTDKELAVQYLNTFY------GCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNT 93
D + D + A +YL ++Y G KE+ + + L++MQ FFGL TG LD NT
Sbjct: 29 DDLSEEDLQFAERYLRSYYHPTNLAGILKENA-ASSMTERLREMQSFFGLEVTGKLDDNT 87
Query: 94 IETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSD 153
++ M+KPRCG PDV YN FPR KW K +TYRI+ YTPD+ V+ AF +AF+VWSD
Sbjct: 88 LDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSD 147
Query: 154 VTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELW 213
VTPL F+R+HDG ADIMI+FG EHGD YPFDG GLLAHAF PG GGD+HFDDDE W
Sbjct: 148 VTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETW 207
Query: 214 T 214
T
Sbjct: 208 T 208
>sp|P28862|COG3_MOUSE STROMELYSIN-1 PRECURSOR (MATRIX METALLOPROTEINASE-3) (MMP-3)
(TRANSIN-1) (SL-1)
pir||KCMSS1 stromelysin 1 (EC 3.4.24.17) precursor - mouse
emb|CAA47029.1| (X66402) stromelysin-i [Mus musculus]
Length = 477
Score = 214 bits (539), Expect = 3e-54
Identities = 112/288 (38%), Positives = 159/288 (54%), Gaps = 11/288 (3%)
Query: 379 ANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIY---TYTKNFRLSQ 435
A++DDD +W G +LFLVAAHE GH++GL HS ALM P+Y T F LSQ
Sbjct: 195 AHFDDDERWTE-DVTGTNLFLVAAHELGHSLGLYHSAKAEALMYPVYKSSTDLSRFHLSQ 253
Query: 436 DDIKGIQELYG---ASPDIDXXXXXXXXXXXXXXEICKQDIVFDGIAQIRGEIFFFKDRF 492
DD+ GIQ LYG ASPD+ +C + FD ++ +RGE+ FFKDR
Sbjct: 254 DDVDGIQSLYGTPTASPDVLVVPTKSNSLEPETSPMCSSTLFFDAVSTLRGEVLFFKDRH 313
Query: 493 IWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGY 552
WR +P L+++FWP LP +DA YE + F GN++W GY
Sbjct: 314 FWRKSLRTPEPEF-YLISSFWPSLPSNMDAAYEVTNRDTVFIFKGNQFWAIRGHEELAGY 372
Query: 553 PKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNA 612
PK + +LGLP V+++DAA + + +KTY F DK+WR++E K+ M+PGFP+ IA+ +
Sbjct: 373 PKSIHTLGLPATVKKIDAAISNKEKRKTYFFVEDKYWRFDEKKQSMEPGFPRKIAEDFPG 432
Query: 613 IPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
+ +DAV + G YFF G+ L+ + + K V + W C
Sbjct: 433 VDSRVDAV--FEAFGFLYFFSGSSQLEFD-PNAKKVTHILKSNSWFNC 477
Score = 203 bits (510), Expect = 7e-51
Identities = 95/173 (54%), Positives = 118/173 (67%), Gaps = 6/173 (3%)
Query: 48 ELAVQYLNTFYGCPKESCNLFVLKDT------LKKMQKFFGLPQTGDLDQNTIETMRKPR 101
EL +YL +YG K+ KD+ +++MQKF GL TG LD NT+E M KPR
Sbjct: 32 ELLQKYLENYYGLAKDVKQFIKKKDSSLIVKKIQEMQKFLGLEMTGKLDSNTMELMHKPR 91
Query: 102 CGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSR 161
CG PDV ++ FP PKW K+ ITYRI+ YTPDL ++VD A +A +VW +VTPL FSR
Sbjct: 92 CGVPDVGGFSTFPGSPKWRKSHITYRIVNYTPDLPRQSVDSAIEKALKVWEEVTPLTFSR 151
Query: 162 IHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWT 214
I +GEADIMI+F EHGD PFDG +LAHA+APG G+ GD+HFDDDE WT
Sbjct: 152 ISEGEADIMISFAVGEHGDFVPFDGPGTVLAHAYAPGPGINGDAHFDDDERWT 204
>ref|NP_034939.1| matrix metalloproteinase 3; progelatinase; stromelysin 1 [Mus
musculus]
emb|CAA44860.1| (X63162) transin-1 [Mus musculus]
Length = 479
Score = 214 bits (539), Expect = 3e-54
Identities = 112/288 (38%), Positives = 159/288 (54%), Gaps = 11/288 (3%)
Query: 379 ANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIY---TYTKNFRLSQ 435
A++DDD +W G +LFLVAAHE GH++GL HS ALM P+Y T F LSQ
Sbjct: 197 AHFDDDERWTE-DVTGTNLFLVAAHELGHSLGLYHSAKAEALMYPVYKSSTDLSRFHLSQ 255
Query: 436 DDIKGIQELYG---ASPDIDXXXXXXXXXXXXXXEICKQDIVFDGIAQIRGEIFFFKDRF 492
DD+ GIQ LYG ASPD+ +C + FD ++ +RGE+ FFKDR
Sbjct: 256 DDVDGIQSLYGTPTASPDVLVVPTKSNSLEPETSPMCSSTLFFDAVSTLRGEVLFFKDRH 315
Query: 493 IWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGY 552
WR +P L+++FWP LP +DA YE + F GN++W GY
Sbjct: 316 FWRKSLRTPEPEF-YLISSFWPSLPSNMDAAYEVTNRDTVFIFKGNQFWAIRGHEELAGY 374
Query: 553 PKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNA 612
PK + +LGLP V+++DAA + + +KTY F DK+WR++E K+ M+PGFP+ IA+ +
Sbjct: 375 PKSIHTLGLPATVKKIDAAISNKEKRKTYFFVEDKYWRFDEKKQSMEPGFPRKIAEDFPG 434
Query: 613 IPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 660
+ +DAV + G YFF G+ L+ + + K V + W C
Sbjct: 435 VDSRVDAV--FEAFGFLYFFSGSSQLEFD-PNAKKVTHILKSNSWFNC 479
Score = 203 bits (510), Expect = 7e-51
Identities = 95/173 (54%), Positives = 118/173 (67%), Gaps = 6/173 (3%)
Query: 48 ELAVQYLNTFYGCPKESCNLFVLKDT------LKKMQKFFGLPQTGDLDQNTIETMRKPR 101
EL +YL +YG K+ KD+ +++MQKF GL TG LD NT+E M KPR
Sbjct: 34 ELLQKYLENYYGLAKDVKQFIKKKDSSLIVKKIQEMQKFLGLEMTGKLDSNTMELMHKPR 93
Query: 102 CGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSR 161
CG PDV ++ FP PKW K+ ITYRI+ YTPDL ++VD A +A +VW +VTPL FSR
Sbjct: 94 CGVPDVGGFSTFPGSPKWRKSHITYRIVNYTPDLPRQSVDSAIEKALKVWEEVTPLTFSR 153
Query: 162 IHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWT 214
I +GEADIMI+F EHGD PFDG +LAHA+APG G+ GD+HFDDDE WT
Sbjct: 154 ISEGEADIMISFAVGEHGDFVPFDGPGTVLAHAYAPGPGINGDAHFDDDERWT 206
Database: nr
Number of letters in database: 182,691,300
Number of sequences in database: 580,189
Lambda K H
0.320 0.141 0.458
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 273039751
Number of Sequences: 580189
Number of extensions: 13102067
Number of successful extensions: 26909
Number of sequences better than 10.0: 390
Number of HSP's better than 10.0 without gapping: 339
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 24230
Number of HSP's gapped (non-prelim): 1079
length of query: 660
length of database: 182,691,300
effective HSP length: 50
effective length of query: 610
effective length of database: 153,681,850
effective search space: 93745928500
effective search space used: 93745928500
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 74 (33.2 bits)
