Score E
Sequences producing significant alignments: (bits) Value
ref|NP_003230.1| transforming growth factor, beta 3 [Homo s... 812 0.0
emb|CAA33024.1| (X14885) ransforming growth factor-beta 3 [... 808 0.0
ref|NP_037306.1| transforming growth factor, beta 3 [Rattus... 795 0.0
pir||A55706 transforming growth factor beta-3 precursor - rat 792 0.0
ref|NP_033394.1| transforming growth factor, beta 3 [Mus mu... 790 0.0
sp|P15203|TGF3_PIG TRANSFORMING GROWTH FACTOR BETA 3 PRECUR... 736 0.0
sp|P16047|TGF3_CHICK TRANSFORMING GROWTH FACTOR BETA 3 PREC... 735 0.0
emb|CAA41128.2| (X58127) transforming growth factor-beta3 [... 726 0.0
pir||S36124 transforming growth factor beta-3 - chicken 480 e-134
ref|NP_033393.1| transforming growth factor, beta 2 [Mus mu... 438 e-122
ref|NP_003229.1| transforming growth factor, beta 2 [Homo s... 436 e-121
sp|P09858|TGF2_PIG TRANSFORMING GROWTH FACTOR BETA 2 PRECUR... 435 e-121
gb|AAB03850.1| (L08375) transforming growth factor beta 2 [... 435 e-121
sp|P30371|TGF2_CHICK TRANSFORMING GROWTH FACTOR BETA 2 PREC... 433 e-120
gb|AAD34160.1|AF153013_1 (AF153013) TGF-beta 2 short form p... 432 e-120
gb|AAA50405.1| (M19154) transforming growth factor beta 2 [... 432 e-120
gb|AAD24484.1|AF135598_1 (AF135598) transforming growth fac... 430 e-119
emb|CAB42003.1| (AJ132718) TGF-beta2 protein [Rattus norveg... 428 e-119
pir||B31249 transforming growth factor beta-2 precursor, lo... 426 e-118
gb|AAD34159.1|AF153012_1 (AF153012) TGF-beta 2 long form pr... 424 e-117
sp|P17247|TGF2_XENLA TRANSFORMING GROWTH FACTOR BETA 2 PREC... 422 e-117
emb|CAA36117.1| (X51817) pro-TGF-beta2 [Xenopus laevis] 419 e-116
gb|AAG02247.1| (AY007214) transforming growth factor-beta 2... 417 e-115
gb|AAB62983.1| (U66874) transforming growth factor-beta 2 [... 384 e-106
ref|NP_067589.1| transforming growth factor beta-1 gene [Ra... 311 1e-83
ref|NP_035707.1| transforming growth factor, beta 1; TGF-be... 308 7e-83
pir||A27512 transforming growth factor beta-1 precursor - p... 307 2e-82
sp|P07200|TGF1_PIG TRANSFORMING GROWTH FACTOR BETA 1 PRECUR... 306 3e-82
sp|P54831|TGF1_CANFA TRANSFORMING GROWTH FACTOR BETA 1 PREC... 304 1e-81
gb|AAD49431.1| (AF175709) transforming growth factor beta 1... 303 2e-81
sp|P01137|TGF1_HUMAN TRANSFORMING GROWTH FACTOR BETA 1 PREC... 303 3e-81
pir||S01413 transforming growth factor beta-1 precursor - c... 303 3e-81
sp|O19011|TGF1_HORSE TRANSFORMING GROWTH FACTOR BETA 1 PREC... 302 7e-81
sp|P09533|TGF1_CERAE TRANSFORMING GROWTH FACTOR BETA 1 PREC... 302 7e-81
ref|NP_000651.1| transforming growth factor, beta 1; diaphy... 301 9e-81
sp|P50414|TGF1_SHEEP TRANSFORMING GROWTH FACTOR BETA 1 PREC... 299 4e-80
gb|AAF02780.1|AF191297_1 (AF191297) transforming growth fac... 293 3e-78
sp|P09531|TGF1_CHICK TRANSFORMING GROWTH FACTOR BETA 1 PREC... 292 4e-78
sp|P16176|TGF1_XENLA TRANSFORMING GROWTH FACTOR BETA 1 PREC... 290 2e-77
sp|P18341|TGF1_BOVIN TRANSFORMING GROWTH FACTOR BETA 1 PREC... 270 2e-71
gb|AAD46997.1|AF140363_1 (AF140363) transforming growth fac... 266 4e-70
emb|CAA07707.1| (AJ007836) transforming growth factor-beta ... 257 2e-67
gb|AAF22573.1|AF136947_1 (AF136947) transforming growth fac... 253 3e-66
pdb|1TGJ| Human Transforming Growth Factor-Beta 3, Crysta... 250 2e-65
pir||A34941 transforming growth factor beta-4 precursor - c... 248 1e-64
sp|P21214|TGF2_BOVIN TRANSFORMING GROWTH FACTOR BETA 2 (TGF... 212 5e-54
pdb|1KLA|A Chain A, Solution Structure Of Tgf-B1, Nmr, Mode... 199 6e-50
pir||I48196 transforming growth factor beta-1 precursor - g... 198 8e-50
gb|AAA31526.1| (L36038) transforming growth factor-beta 1 [... 196 5e-49
emb|CAA67685.1| (X99303) TGF [Oncorhynchus mykiss] 192 5e-48
>ref|NP_003230.1| transforming growth factor, beta 3 [Homo sapiens]
sp|P10600|TGF3_HUMAN TRANSFORMING GROWTH FACTOR BETA 3 PRECURSOR (TGF-BETA 3)
pir||A36169 transforming growth factor beta-3 precursor - human
emb|CAA32362.1| (X14149) TGF-beta 3 (AA 1-412) [Homo sapiens]
gb|AAA61161.1| (J03241) transforming growth factor-beta3 [Homo sapiens]
gb|AAC79727.1| (AF107885) transforming growth factor-beta 3 [Homo sapiens]
Length = 412
Score = 812 bits (2074), Expect = 0.0
Identities = 388/412 (94%), Positives = 388/412 (94%)
Query: 1 MKMHLQRALVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEPT 60
MKMHLQRALVVLALLNFATV DFGHIKKKRVEAIRGQILSKLRLTSPPEPT
Sbjct: 1 MKMHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPT 60
Query: 61 VMTHVPYQVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNEL 120
VMTHVPYQVLALYNST CTQENTESEYYAKEIHKFDMIQGLAEHNEL
Sbjct: 61 VMTHVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNEL 120
Query: 121 AVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHI 180
AVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHI
Sbjct: 121 AVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHI 180
Query: 181 AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE 240
AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE
Sbjct: 181 AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE 240
Query: 241 NIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR 300
NIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR
Sbjct: 241 NIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR 300
Query: 301 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST 360
ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST
Sbjct: 301 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST 360
Query: 361 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
Sbjct: 361 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
>emb|CAA33024.1| (X14885) ransforming growth factor-beta 3 [Homo sapiens]
Length = 410
Score = 808 bits (2064), Expect = 0.0
Identities = 386/410 (94%), Positives = 386/410 (94%)
Query: 3 MHLQRALVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEPTVM 62
MHLQRALVVLALLNFATV DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVM
Sbjct: 1 MHLQRALVVLALLNFATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPTVM 60
Query: 63 THVPYQVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAV 122
THVPYQVLALYNST CTQENTESEYYAKEIHKFDMIQGLAEHNELAV
Sbjct: 61 THVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNELAV 120
Query: 123 CPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK 182
CPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK
Sbjct: 121 CPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK 180
Query: 183 QRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENI 242
QRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENI
Sbjct: 181 QRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENI 240
Query: 243 HEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRAL 302
HEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRAL
Sbjct: 241 HEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRAL 300
Query: 303 DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVL 362
DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVL
Sbjct: 301 DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVL 360
Query: 363 GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
Sbjct: 361 GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 410
>ref|NP_037306.1| transforming growth factor, beta 3 [Rattus norvegicus]
sp|Q07258|TGF3_RAT TRANSFORMING GROWTH FACTOR BETA 3 PRECURSOR (TGF-BETA 3)
gb|AAA67915.1| (U03491) transforming growth factor beta-3 [Rattus norvegicus]
Length = 412
Score = 795 bits (2032), Expect = 0.0
Identities = 379/412 (91%), Positives = 384/412 (92%)
Query: 1 MKMHLQRALVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEPT 60
MKMHLQRALVVLALLN ATV DFGHIKKKRVEAIRGQILSKLRLTSPPEP+
Sbjct: 1 MKMHLQRALVVLALLNLATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPS 60
Query: 61 VMTHVPYQVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNEL 120
VMTHVPYQVLALYNST CTQE +ESEYYAKEIHKFDMIQGLAEHNEL
Sbjct: 61 VMTHVPYQVLALYNSTRELLEEMHGEREEGCTQETSESEYYAKEIHKFDMIQGLAEHNEL 120
Query: 121 AVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHI 180
AVCPKGITSKVFRFNVSSVEKN TNLFRAEFRVLRVPNPSSKR EQRIELFQILRPDEHI
Sbjct: 121 AVCPKGITSKVFRFNVSSVEKNGTNLFRAEFRVLRVPNPSSKRTEQRIELFQILRPDEHI 180
Query: 181 AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE 240
AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE
Sbjct: 181 AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE 240
Query: 241 NIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR 300
N+HEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLD+PGQGGQRKKR
Sbjct: 241 NVHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDSPGQGGQRKKR 300
Query: 301 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST 360
ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRS+DTTHST
Sbjct: 301 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSSDTTHST 360
Query: 361 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
Sbjct: 361 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
>pir||A55706 transforming growth factor beta-3 precursor - rat
Length = 410
Score = 792 bits (2022), Expect = 0.0
Identities = 377/410 (91%), Positives = 382/410 (92%)
Query: 3 MHLQRALVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEPTVM 62
MHLQRALVVLALLN ATV DFGHIKKKRVEAIRGQILSKLRLTSPPEP+VM
Sbjct: 1 MHLQRALVVLALLNLATVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPSVM 60
Query: 63 THVPYQVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAV 122
THVPYQVLALYNST CTQE +ESEYYAKEIHKFDMIQGLAEHNELAV
Sbjct: 61 THVPYQVLALYNSTRELLEEMHGEREEGCTQETSESEYYAKEIHKFDMIQGLAEHNELAV 120
Query: 123 CPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK 182
CPKGITSKVFRFNVSSVEKN TNLFRAEFRVLRVPNPSSKR EQRIELFQILRPDEHIAK
Sbjct: 121 CPKGITSKVFRFNVSSVEKNGTNLFRAEFRVLRVPNPSSKRTEQRIELFQILRPDEHIAK 180
Query: 183 QRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENI 242
QRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILEN+
Sbjct: 181 QRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENV 240
Query: 243 HEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRAL 302
HEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLD+PGQGGQRKKRAL
Sbjct: 241 HEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDSPGQGGQRKKRAL 300
Query: 303 DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVL 362
DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRS+DTTHSTVL
Sbjct: 301 DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSSDTTHSTVL 360
Query: 363 GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
Sbjct: 361 GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 410
>ref|NP_033394.1| transforming growth factor, beta 3 [Mus musculus]
sp|P17125|TGF3_MOUSE TRANSFORMING GROWTH FACTOR BETA 3 PRECURSOR (TGF-BETA 3)
pir||A41397 transforming growth factor beta-3 precursor - mouse
gb|AAA40422.1| (M32745) transforming growth factor beta-3 (TGF beta-3) precursor
(start site 611 could be 368 or 477) [Mus musculus]
Length = 410
Score = 790 bits (2018), Expect = 0.0
Identities = 376/410 (91%), Positives = 381/410 (92%)
Query: 3 MHLQRALVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEPTVM 62
MHLQRALVVLALLN AT+ DFGHIKKKRVEAIRGQILSKLRLTSPPEP+VM
Sbjct: 1 MHLQRALVVLALLNLATISLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPSVM 60
Query: 63 THVPYQVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAV 122
THVPYQVLALYNST CTQE +ESEYYAKEIHKFDMIQGLAEHNELAV
Sbjct: 61 THVPYQVLALYNSTRELLEEMHGEREEGCTQETSESEYYAKEIHKFDMIQGLAEHNELAV 120
Query: 123 CPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK 182
CPKGITSKVFRFNVSSVEKN TNLFRAEFRVLRVPNPSSKR EQRIELFQILRPDEHIAK
Sbjct: 121 CPKGITSKVFRFNVSSVEKNGTNLFRAEFRVLRVPNPSSKRTEQRIELFQILRPDEHIAK 180
Query: 183 QRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENI 242
QRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILEN+
Sbjct: 181 QRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENV 240
Query: 243 HEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRAL 302
HEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLD+PGQG QRKKRAL
Sbjct: 241 HEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDSPGQGSQRKKRAL 300
Query: 303 DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVL 362
DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVL
Sbjct: 301 DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVL 360
Query: 363 GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
Sbjct: 361 GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 410
>sp|P15203|TGF3_PIG TRANSFORMING GROWTH FACTOR BETA 3 PRECURSOR (TGF-BETA 3)
pir||S01825 transforming growth factor beta-3 precursor - pig
emb|CAA32363.1| (X14150) TGF-beta 3 (AA 1-409) [Sus scrofa]
Length = 409
Score = 736 bits (1879), Expect = 0.0
Identities = 353/410 (86%), Positives = 371/410 (90%), Gaps = 1/410 (0%)
Query: 3 MHLQRALVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEPTVM 62
MHLQRALVVLALLNFATV DF HIK+KRVEAIRGQILSKLRLTSPP+P+++
Sbjct: 1 MHLQRALVVLALLNFATVSLSMSTCTTLDFDHIKRKRVEAIRGQILSKLRLTSPPDPSML 60
Query: 63 THVPYQVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAV 122
++P QVL LYNST CTQENTESEYYAKEI+KFDMIQGL EHN+LAV
Sbjct: 61 ANIPTQVLDLYNSTRELLEEVHGERGDDCTQENTESEYYAKEIYKFDMIQGLEEHNDLAV 120
Query: 123 CPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK 182
CPKGITSK+FRFNVSSVEKN TNLFRAEFRVLR+PNPSSKR+EQRIELFQIL+PDEHIAK
Sbjct: 121 CPKGITSKIFRFNVSSVEKNETNLFRAEFRVLRMPNPSSKRSEQRIELFQILQPDEHIAK 180
Query: 183 QRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENI 242
QRYI GKNLPTRG AEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENI
Sbjct: 181 QRYIDGKNLPTRGAAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENI 240
Query: 243 HEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRAL 302
EVMEIKFKGVD+EDD GRGDLGRLKK+K+ H+PHLILMMIPP RLDNPG G QRKKRAL
Sbjct: 241 QEVMEIKFKGVDSEDDPGRGDLGRLKKKKE-HSPHLILMMIPPDRLDNPGLGAQRKKRAL 299
Query: 303 DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVL 362
DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHS+VL
Sbjct: 300 DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSSVL 359
Query: 363 GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
GLYNTLNPEASASPCCVPQDLEPLTILYYVGRT KVEQLSNMVVKSCKCS
Sbjct: 360 GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTAKVEQLSNMVVKSCKCS 409
>sp|P16047|TGF3_CHICK TRANSFORMING GROWTH FACTOR BETA 3 PRECURSOR (TGF-BETA 3)
pir||A34939 transforming growth factor beta-3 precursor - chicken
gb|AAA49089.1| (M31154) transforming growth factor beta precursor [Gallus gallus]
Length = 412
Score = 735 bits (1877), Expect = 0.0
Identities = 346/412 (83%), Positives = 368/412 (88%)
Query: 1 MKMHLQRALVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEPT 60
MKM+ QRALV+L+LL+FATV D HIKKKRVEAIRGQILSKLRLTSPPE
Sbjct: 1 MKMYAQRALVLLSLLSFATVSLALSSCTTLDLEHIKKKRVEAIRGQILSKLRLTSPPESV 60
Query: 61 VMTHVPYQVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNEL 120
HVPYQ+LALYNST C+QENTESEYYAKEIHKFDMIQGL EHNEL
Sbjct: 61 GPAHVPYQILALYNSTRELLEEMEEEKEESCSQENTESEYYAKEIHKFDMIQGLPEHNEL 120
Query: 121 AVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHI 180
+CPKG+TS VFRFNVSS EKN TNLFRAEFRVLRVPNPSSKR+EQRIELFQILRPDEHI
Sbjct: 121 GICPKGVTSNVFRFNVSSAEKNSTNLFRAEFRVLRVPNPSSKRSEQRIELFQILRPDEHI 180
Query: 181 AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE 240
AKQRY+ G+N+ TRG+ EWLSFDVTDTVREWLL RESNLGLEISIHCPCHTFQPNGDILE
Sbjct: 181 AKQRYLSGRNVQTRGSPEWLSFDVTDTVREWLLHRESNLGLEISIHCPCHTFQPNGDILE 240
Query: 241 NIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR 300
N+HEV+EIKFKG+D+EDD+GRGDLGRLKKQKD HNPHLILMM+PPHRL++P GGQRKKR
Sbjct: 241 NLHEVLEIKFKGIDSEDDYGRGDLGRLKKQKDLHNPHLILMMLPPHRLESPTLGGQRKKR 300
Query: 301 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST 360
ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGY+ANFCSGPCPYLRSADTTHST
Sbjct: 301 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYFANFCSGPCPYLRSADTTHST 360
Query: 361 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
Sbjct: 361 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
>emb|CAA41128.2| (X58127) transforming growth factor-beta3 [Gallus gallus]
Length = 412
Score = 726 bits (1854), Expect = 0.0
Identities = 342/412 (83%), Positives = 365/412 (88%)
Query: 1 MKMHLQRALVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEPT 60
MKM+ QRALV+L+LL+FATV D HIKKKRVEAIRGQILSKLRLTSPPE
Sbjct: 1 MKMYAQRALVLLSLLSFATVSLALSSCTTLDLEHIKKKRVEAIRGQILSKLRLTSPPESV 60
Query: 61 VMTHVPYQVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNEL 120
HVPYQ+LALYNST C+QENTESEYYAKEIHKFDMIQGL EHNEL
Sbjct: 61 GPAHVPYQILALYNSTRELLEEMEEEKEESCSQENTESEYYAKEIHKFDMIQGLPEHNEL 120
Query: 121 AVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHI 180
+CPKG+TS VFRFNVSS EKN TNLFRAEFRVLRVPNPSSKR+EQRIELFQILRPDEHI
Sbjct: 121 GICPKGVTSNVFRFNVSSAEKNSTNLFRAEFRVLRVPNPSSKRSEQRIELFQILRPDEHI 180
Query: 181 AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE 240
AKQRY+ G+N+ TRG+ EWLSFDVTDTVREWLL RESNLGLEISIHCPCHTFQPNGDILE
Sbjct: 181 AKQRYLSGRNVQTRGSPEWLSFDVTDTVREWLLHRESNLGLEISIHCPCHTFQPNGDILE 240
Query: 241 NIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR 300
N+HEV+EIKFKG+D+EDD+GRGDLGRLKKQKD HNPHLILMM+PPHRL++P GGQRKKR
Sbjct: 241 NLHEVLEIKFKGIDSEDDYGRGDLGRLKKQKDLHNPHLILMMLPPHRLESPTLGGQRKKR 300
Query: 301 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST 360
ALDTNYCFRNLEENCCVRPLYI+ DLGWKWVHEPKGY+ANFCSGPCPYLRSADTTHST
Sbjct: 301 ALDTNYCFRNLEENCCVRPLYIELPTDLGWKWVHEPKGYFANFCSGPCPYLRSADTTHST 360
Query: 361 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
Sbjct: 361 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
>pir||S36124 transforming growth factor beta-3 - chicken
Length = 240
Score = 480 bits (1221), Expect = e-134
Identities = 216/240 (90%), Positives = 230/240 (95%)
Query: 173 ILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTF 232
ILRPDEHIAKQRY+ G+N+ TRG+ EWLSFDVTDTVREWLL RESNLGLEISIHCPCHTF
Sbjct: 1 ILRPDEHIAKQRYLSGRNVQTRGSPEWLSFDVTDTVREWLLHRESNLGLEISIHCPCHTF 60
Query: 233 QPNGDILENIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPG 292
QPNGDILEN+HEV+EIKFKG+D+EDD+GRGDLGRLKKQKD HNPHLILMM+PPHRL++P
Sbjct: 61 QPNGDILENLHEVLEIKFKGIDSEDDYGRGDLGRLKKQKDLHNPHLILMMLPPHRLESPT 120
Query: 293 QGGQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLR 352
GGQRKKRALDTNYCFRNLEENCCVRPLYI+ DLGWKWVHEPKGY+ANFCSGPCPYLR
Sbjct: 121 LGGQRKKRALDTNYCFRNLEENCCVRPLYIELPTDLGWKWVHEPKGYFANFCSGPCPYLR 180
Query: 353 SADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
SADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
Sbjct: 181 SADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 240
>ref|NP_033393.1| transforming growth factor, beta 2 [Mus musculus]
sp|P27090|TGF2_MOUSE TRANSFORMING GROWTH FACTOR BETA 2 PRECURSOR (TGF-BETA 2)
pir||WFMSB2 transforming growth factor beta-2 precursor - mouse
emb|CAA40672.1| (X57413) transforming growth factor-beta2 precurser [Mus musculus]
Length = 414
Score = 438 bits (1114), Expect = e-122
Identities = 216/410 (52%), Positives = 277/410 (66%), Gaps = 7/410 (1%)
Query: 9 LVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEP-TVMTHVPY 67
L LL+ V D +KR+EAIRGQILSKL+LTSPPE VP
Sbjct: 6 LSTFLLLHLVPVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPDEVPP 65
Query: 68 QVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGI 127
+V+++YNST C +E +E EYYAKE++K DM L N +
Sbjct: 66 EVISIYNSTRDLLQEKASRRAAACERERSEQEYYAKEVYKIDMPSHLPSENAIPPTFYRP 125
Query: 128 TSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK-QRYI 186
++ RF+VS++EKN +NL +AEFRV R+ NP ++ EQRIEL+QIL+ + + QRYI
Sbjct: 126 YFRIVRFDVSTMEKNASNLVKAEFRVFRLQNPKARVAEQRIELYQILKSKDLTSPTQRYI 185
Query: 187 GGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQP-NGDILENIHEV 245
K + TR EWLSFDVTD V+EWL ++ NLG +IS+HCPC TF P N I+ N E
Sbjct: 186 DSKVVKTRAEGEWLSFDVTDAVQEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEE 245
Query: 246 MEIKFKGVDNEDDHGRGDLGRLK---KQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRAL 302
+E +F G+D + GD +K K+ PHL+LM++P +RL++ Q +RKKRAL
Sbjct: 246 LEARFAGIDGTSTYASGDQKTIKSTRKKTSGKTPHLLLMLLPSYRLESQ-QSSRRKKRAL 304
Query: 303 DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVL 362
D YCFRN+++NCC+RPLYIDF++DLGWKW+HEPKGY ANFC+G CPYL S+DT H+ VL
Sbjct: 305 DAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHTKVL 364
Query: 363 GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
LYNT+NPEASASPCCV QDLEPLTILYY+G TPK+EQLSNM+VKSCKCS
Sbjct: 365 SLYNTINPEASASPCCVSQDLEPLTILYYIGNTPKIEQLSNMIVKSCKCS 414
>ref|NP_003229.1| transforming growth factor, beta 2 [Homo sapiens]
sp|P08112|TGF2_HUMAN TRANSFORMING GROWTH FACTOR BETA 2 PRECURSOR (TGF-BETA 2)
(GLIOBLASTOMA -DERIVED T-CELL SUPPRESSOR FACTOR) (G-TSF)
(BSC-1 CELL GROWTH INHIBITOR) (POLYERGIN) (CETERMIN)
pir||WFMKB2 transforming growth factor beta-2 precursor, short form - green
monkey
pir||A31249 transforming growth factor beta-2 precursor, short form - human
emb|CAA68279.1| (Y00083) G-Tsf precursor [Homo sapiens]
gb|AAA35358.1| (J03585) polyergin precursor [Cercopithecus aethiops]
Length = 414
Score = 436 bits (1110), Expect = e-121
Identities = 215/410 (52%), Positives = 277/410 (67%), Gaps = 7/410 (1%)
Query: 9 LVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEP-TVMTHVPY 67
L +L+ TV D +KR+EAIRGQILSKL+LTSPPE VP
Sbjct: 6 LSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPEEVPP 65
Query: 68 QVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGI 127
+V+++YNST C +E ++ EYYAKE++K DM N +
Sbjct: 66 EVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSENAIPPTFYRP 125
Query: 128 TSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK-QRYI 186
++ RF+VS++EKN +NL +AEFRV R+ NP ++ EQRIEL+QIL+ + + QRYI
Sbjct: 126 YFRIVRFDVSAMEKNASNLVKAEFRVFRLQNPKARVPEQRIELYQILKSKDLTSPTQRYI 185
Query: 187 GGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQP-NGDILENIHEV 245
K + TR EWLSFDVTD V EWL ++ NLG +IS+HCPC TF P N I+ N E
Sbjct: 186 DSKVVKTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEE 245
Query: 246 MEIKFKGVDNEDDHGRGDLGRLK---KQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRAL 302
+E +F G+D + GD +K K+ PHL+LM++P +RL++ Q +RKKRAL
Sbjct: 246 LEARFAGIDGTSTYTSGDQKTIKSTRKKNSGKTPHLLLMLLPSYRLESQ-QTNRRKKRAL 304
Query: 303 DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVL 362
D YCFRN+++NCC+RPLYIDF++DLGWKW+HEPKGY ANFC+G CPYL S+DT HS VL
Sbjct: 305 DAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHSRVL 364
Query: 363 GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
LYNT+NPEASASPCCV QDLEPLTILYY+G+TPK+EQLSNM+VKSCKCS
Sbjct: 365 SLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMIVKSCKCS 414
>sp|P09858|TGF2_PIG TRANSFORMING GROWTH FACTOR BETA 2 PRECURSOR (TGF-BETA 2)
Length = 435
Score = 435 bits (1107), Expect = e-121
Identities = 215/410 (52%), Positives = 276/410 (66%), Gaps = 7/410 (1%)
Query: 9 LVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEP-TVMTHVPY 67
L LL+ TV D +KR+EAIRGQILSKL+LTSPPE VP
Sbjct: 6 LSAFLLLHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPEEVPP 65
Query: 68 QVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGI 127
+V+++YNST C +E ++ EYYAKE++K DM N +
Sbjct: 66 EVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSENAIPPTFYRP 125
Query: 128 TSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK-QRYI 186
++ RF+VS++EKN +NL +AEFRV R+ NP ++ EQRIEL+QIL+ + + QRYI
Sbjct: 126 YFRIVRFDVSAMEKNASNLVKAEFRVFRLQNPKARVAEQRIELYQILKSKDLTSPTQRYI 185
Query: 187 GGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQP-NGDILENIHEV 245
K + TR EWLSFDVTD V EWL ++ NLG +IS+HCPC TF P N I+ N E
Sbjct: 186 DSKVVKTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEE 245
Query: 246 MEIKFKGVDNEDDHGRGDLGRLK---KQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRAL 302
+E +F G+D + GD +K K+ PHL+LM++P + L++ Q +RKKRAL
Sbjct: 246 LEARFAGIDGTSTYTSGDQKTIKSTRKKNSGKTPHLLLMLLPSYGLESQ-QSNRRKKRAL 304
Query: 303 DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVL 362
D YCFRN+++NCC+RPLYIDF++DLGWKW+HEPKGY ANFC+G CPYL S+DT HS VL
Sbjct: 305 DAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHSRVL 364
Query: 363 GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
LYNT+NPEASASPCCV QDLEPLTILYY+G+TPK+EQLSNM+VKSCKCS
Sbjct: 365 SLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMIVKSCKCS 414
>gb|AAB03850.1| (L08375) transforming growth factor beta 2 [Sus scrofa]
Length = 434
Score = 435 bits (1107), Expect = e-121
Identities = 215/410 (52%), Positives = 276/410 (66%), Gaps = 7/410 (1%)
Query: 9 LVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEP-TVMTHVPY 67
L LL+ TV D +KR+EAIRGQILSKL+LTSPPE VP
Sbjct: 5 LSAFLLLHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPEEVPP 64
Query: 68 QVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGI 127
+V+++YNST C +E ++ EYYAKE++K DM N +
Sbjct: 65 EVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSENAIPPTFYRP 124
Query: 128 TSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK-QRYI 186
++ RF+VS++EKN +NL +AEFRV R+ NP ++ EQRIEL+QIL+ + + QRYI
Sbjct: 125 YFRIVRFDVSAMEKNASNLVKAEFRVFRLQNPKARVAEQRIELYQILKSKDLTSPTQRYI 184
Query: 187 GGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQP-NGDILENIHEV 245
K + TR EWLSFDVTD V EWL ++ NLG +IS+HCPC TF P N I+ N E
Sbjct: 185 DSKVVKTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEE 244
Query: 246 MEIKFKGVDNEDDHGRGDLGRLK---KQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRAL 302
+E +F G+D + GD +K K+ PHL+LM++P + L++ Q +RKKRAL
Sbjct: 245 LEARFAGIDGTSTYTSGDQKTIKSTRKKNSGKTPHLLLMLLPSYGLESQ-QSNRRKKRAL 303
Query: 303 DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVL 362
D YCFRN+++NCC+RPLYIDF++DLGWKW+HEPKGY ANFC+G CPYL S+DT HS VL
Sbjct: 304 DAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHSRVL 363
Query: 363 GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
LYNT+NPEASASPCCV QDLEPLTILYY+G+TPK+EQLSNM+VKSCKCS
Sbjct: 364 SLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMIVKSCKCS 413
>sp|P30371|TGF2_CHICK TRANSFORMING GROWTH FACTOR BETA 2 PRECURSOR (TGF-BETA 2)
pir||A39489 transforming growth factor beta-2 precursor - chicken
emb|CAA41101.1| (X58071) transforming growth factor-beta2 [Gallus gallus]
Length = 412
Score = 433 bits (1101), Expect = e-120
Identities = 216/410 (52%), Positives = 282/410 (68%), Gaps = 9/410 (2%)
Query: 9 LVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPP-EPTVMTHVPY 67
L V L+ A V D +KR+EAIRGQILSKL+LTSPP E VP
Sbjct: 6 LSVFLTLDLAAVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPDEYPEPEEVPP 65
Query: 68 QVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGI 127
+V+++YNST C +E ++ EYYAKE++K DM Q N + +
Sbjct: 66 EVISIYNSTRDLLQEKANHRAATCERERSDEEYYAKEVYKIDM-QPFYPENAIPPSYYSL 124
Query: 128 TSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK-QRYI 186
++ RF+VS++EKN +NL +AEFRV R+ N ++ +EQRIEL+Q+L+ E + QRYI
Sbjct: 125 YFRIVRFDVSAMEKNASNLVKAEFRVFRLQNSKARVSEQRIELYQVLKSKELSSPGQRYI 184
Query: 187 GGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQP-NGDILENIHEV 245
K + TR EWLSFDVT+ V EWL R+ NLG +IS+HCPC TF P N I+ N E
Sbjct: 185 DSKVVKTRAEGEWLSFDVTEAVHEWLHHRDRNLGFKISLHCPCCTFVPSNNYIIPNKSEE 244
Query: 246 MEIKFKGVDNEDDHGRGDLGRLKKQKDHHN---PHLILMMIPPHRLDNPGQGGQRKKRAL 302
E +F G+D+ + GD+ LK + ++ PHL+LM++P +RL++ Q +RKKRAL
Sbjct: 245 PEARFAGIDDYT-YSSGDVKALKSNRKKYSGKTPHLLLMLLPSYRLESQ-QPSRRKKRAL 302
Query: 303 DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVL 362
D YCFRN+++NCC+RPLYIDF++DLGWKW+HEPKGY+ANFC+G CPYL S+DT HS VL
Sbjct: 303 DAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYHANFCAGACPYLWSSDTQHSRVL 362
Query: 363 GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
LYNT+NPEASASPCCV QDLEPLTILYY+G+TPK+EQLSNM+VKSCKCS
Sbjct: 363 SLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMIVKSCKCS 412
>gb|AAD34160.1|AF153013_1 (AF153013) TGF-beta 2 short form precursor [Rattus norvegicus]
Length = 414
Score = 432 bits (1099), Expect = e-120
Identities = 211/405 (52%), Positives = 274/405 (67%), Gaps = 7/405 (1%)
Query: 14 LLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEP-TVMTHVPYQVLAL 72
LL+ V D +KR+EAIRGQILSKL+LTSPPE VP +V+++
Sbjct: 11 LLHLVPVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPDEVPPEVISI 70
Query: 73 YNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVF 132
YNST C +E ++ EYYAKE++K DM N + ++
Sbjct: 71 YNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPSHFPSENAIPPTFYRPYFRIV 130
Query: 133 RFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK-QRYIGGKNL 191
RF+VS++EKN +NL +AEFRV R+ NP ++ EQRIEL+QIL+ + + QRYI K +
Sbjct: 131 RFDVSTMEKNASNLVKAEFRVFRLQNPKARVAEQRIELYQILKSKDLTSPTQRYIDSKVV 190
Query: 192 PTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQP-NGDILENIHEVMEIKF 250
TR EWLSFDVTD V EWL ++ NLG +IS+HCPC TF P N I+ N + +E +F
Sbjct: 191 KTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFIPSNNYIIPNKSQELEARF 250
Query: 251 KGVDNEDDHGRGDLGRLK---KQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYC 307
G+D + GD +K K+ PHL+LM++P +RL++ Q +R+KRALD YC
Sbjct: 251 AGIDGTSTYASGDQKTIKSTRKKSSGKTPHLLLMLLPSYRLESQ-QSSRRRKRALDAAYC 309
Query: 308 FRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNT 367
FRN+++NCC+RPLYIDF++DLGWKW+HEPKGY ANFC+G CPYL S+DT H+ VL LYNT
Sbjct: 310 FRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHTKVLSLYNT 369
Query: 368 LNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
+NPEASASPCCV QDLEPLTILYY+G TPK+EQLSNM+VKSCKCS
Sbjct: 370 INPEASASPCCVSQDLEPLTILYYIGNTPKIEQLSNMIVKSCKCS 414
>gb|AAA50405.1| (M19154) transforming growth factor beta 2 [Homo sapiens]
Length = 413
Score = 432 bits (1099), Expect = e-120
Identities = 216/412 (52%), Positives = 278/412 (67%), Gaps = 12/412 (2%)
Query: 9 LVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEP-TVMTHVPY 67
L +L+ TV D +KR+EAIRGQILSKL+LTSPPE VP
Sbjct: 6 LSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPEEVPP 65
Query: 68 QVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGI 127
+V+++YNST C +E ++ EYYAKE++K DM A+ P
Sbjct: 66 EVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSE---AIPPTFY 122
Query: 128 TS--KVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK-QR 184
++ RF+VS++EKN +NL +AEFRV R+ NP ++ EQRIEL+QIL+ + + QR
Sbjct: 123 RPYFRIVRFDVSAMEKNASNLVKAEFRVFRLQNPKARVPEQRIELYQILKSKDLTSPTQR 182
Query: 185 YIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQP-NGDILENIH 243
YI K + TR EWLSFDVTD V EWL ++ NLG +IS+HCPC TF P N I+ N
Sbjct: 183 YIDSKVVKTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKS 242
Query: 244 EVMEIKFKGVDNEDDHGRGDLGRLK---KQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR 300
E +E +F G+D + GD +K K+ PHL+LM++P +RL++ Q +RKKR
Sbjct: 243 EELEARFAGIDGTSTYTSGDQKTIKSTRKKNSGKTPHLLLMLLPSYRLESQ-QTNRRKKR 301
Query: 301 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST 360
ALD YCFRN+++NCC+RPLYIDF++DLGWKW+HEPKGY ANFC+G CPYL S+DT HS
Sbjct: 302 ALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHSR 361
Query: 361 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
VL LYNT+NPEASASPCCV QDLEPLTILYY+G+TPK+EQLSNM+VKSCKCS
Sbjct: 362 VLSLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMIVKSCKCS 413
>gb|AAD24484.1|AF135598_1 (AF135598) transforming growth factor beta 2 precursor [Rattus
norvegicus]
Length = 414
Score = 430 bits (1094), Expect = e-119
Identities = 211/405 (52%), Positives = 273/405 (67%), Gaps = 7/405 (1%)
Query: 14 LLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEP-TVMTHVPYQVLAL 72
LL+ V D +KR+EAIRGQILSKL+LTSPPE VP +V+++
Sbjct: 11 LLHLVPVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPDEVPPEVISI 70
Query: 73 YNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVF 132
YNST C +E ++ EYYAKE++K DM N + ++
Sbjct: 71 YNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPSHFPSENAIPPTFYRPYFRIV 130
Query: 133 RFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK-QRYIGGKNL 191
RF+VS++EKN +NL +AEFRV R+ NP ++ EQRIEL+QIL+ + + QRYI K +
Sbjct: 131 RFDVSTMEKNASNLVKAEFRVFRLQNPKARVAEQRIELYQILKSKDLTSPTQRYIDSKVV 190
Query: 192 PTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQP-NGDILENIHEVMEIKF 250
TR EWLSFDVTD V EWL ++ NLG +IS+HCPC TF P N I+ N + +E +F
Sbjct: 191 KTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFIPSNNYIIPNKSQELEARF 250
Query: 251 KGVDNEDDHGRGDLGRLK---KQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYC 307
G+D + GD +K K+ PHL LM++P +RL++ Q +R+KRALD YC
Sbjct: 251 AGIDGTSTYASGDQKTIKSTRKKSSGKTPHLPLMLLPSYRLESQ-QSSRRRKRALDAAYC 309
Query: 308 FRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNT 367
FRN+++NCC+RPLYIDF++DLGWKW+HEPKGY ANFC+G CPYL S+DT H+ VL LYNT
Sbjct: 310 FRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHTKVLSLYNT 369
Query: 368 LNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
+NPEASASPCCV QDLEPLTILYY+G TPK+EQLSNM+VKSCKCS
Sbjct: 370 INPEASASPCCVSQDLEPLTILYYIGNTPKIEQLSNMIVKSCKCS 414
>emb|CAB42003.1| (AJ132718) TGF-beta2 protein [Rattus norvegicus]
Length = 414
Score = 428 bits (1088), Expect = e-119
Identities = 210/405 (51%), Positives = 272/405 (66%), Gaps = 7/405 (1%)
Query: 14 LLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEP-TVMTHVPYQVLAL 72
LL+ V D +KR+EAIRGQILSKL+LTSPPE VP +V+++
Sbjct: 11 LLHLVPVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPDEVPPEVISI 70
Query: 73 YNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVF 132
YNST C +E ++ EY AKE++K DM N + ++
Sbjct: 71 YNSTRDLLQEKASRRAAACERERSDEEYCAKEVYKIDMPSHFPSENAIPPTFYRPYFRIV 130
Query: 133 RFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK-QRYIGGKNL 191
RF+VS++EKN +NL +AEFRV R+ NP ++ EQRIEL+QIL+ + + QRYI K +
Sbjct: 131 RFDVSTMEKNASNLVKAEFRVFRLQNPKARVAEQRIELYQILKSKDLTSPTQRYIDSKVV 190
Query: 192 PTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQP-NGDILENIHEVMEIKF 250
TR EWLSFDVTD V EWL ++ NLG +IS+HCPC TF P N I+ N + +E +F
Sbjct: 191 KTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFIPSNNYIIPNKSQELEARF 250
Query: 251 KGVDNEDDHGRGDLGRLK---KQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYC 307
G+D + GD +K K+ PHL+LM++P +RL++ Q +R+KRALD YC
Sbjct: 251 AGIDGTSTYASGDQKTIKSTRKKSSGKTPHLLLMLLPSYRLESQ-QSSRRRKRALDAAYC 309
Query: 308 FRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNT 367
FRN++ NCC+RPLYIDF++DLGWKW+HEPKGY ANFC+G CPYL S+DT H+ VL LYNT
Sbjct: 310 FRNVQHNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHTKVLSLYNT 369
Query: 368 LNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
+NPEASASPCCV QDLEPLTILYY+G TPK+EQLSNM+VKSCKCS
Sbjct: 370 INPEASASPCCVSQDLEPLTILYYIGNTPKIEQLSNMIVKSCKCS 414
>pir||B31249 transforming growth factor beta-2 precursor, long form - human
gb|AAA50404.1| (M19154) transforming growth factor-beta-2 precursor [Homo sapiens]
Length = 442
Score = 426 bits (1084), Expect = e-118
Identities = 219/441 (49%), Positives = 278/441 (62%), Gaps = 41/441 (9%)
Query: 9 LVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEP-TVMTHVPY 67
L +L+ TV D +KR+EAIRGQILSKL+LTSPPE VP
Sbjct: 6 LSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPEEVPP 65
Query: 68 QVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGI 127
+V+++YNST C +E ++ EYYAKE++K DM VCP
Sbjct: 66 EVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSE---TVCPVVT 122
Query: 128 TS-------------------------------KVFRFNVSSVEKNRTNLFRAEFRVLRV 156
T ++ RF+VS++EKN +NL +AEFRV R+
Sbjct: 123 TPSGSVGSLCSRQSQVLCGYLDAIPPTFYRPYFRIVRFDVSAMEKNASNLVKAEFRVFRL 182
Query: 157 PNPSSKRNEQRIELFQILR-PDEHIAKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRR 215
NP ++ EQRIEL+QIL+ D QRYI K + TR EWLSFDVTD V EWL +
Sbjct: 183 QNPKARVPEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVHEWLHHK 242
Query: 216 ESNLGLEISIHCPCHTFQP-NGDILENIHEVMEIKFKGVDNEDDHGRGDLGRLK---KQK 271
+ NLG +IS+HCPC TF P N I+ N E +E +F G+D + GD +K K+
Sbjct: 243 DRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDGTSTYTSGDQKTIKSTRKKN 302
Query: 272 DHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGWK 331
PHL+LM++P +RL++ Q +RKKRALD YCFRN+++NCC+RPLYIDF++DLGWK
Sbjct: 303 SGKTPHLLLMLLPSYRLESQ-QTNRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWK 361
Query: 332 WVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYY 391
W+HEPKGY ANFC+G CPYL S+DT HS VL LYNT+NPEASASPCCV QDLEPLTILYY
Sbjct: 362 WIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILYY 421
Query: 392 VGRTPKVEQLSNMVVKSCKCS 412
+G+TPK+EQLSNM+VKSCKCS
Sbjct: 422 IGKTPKIEQLSNMIVKSCKCS 442
>gb|AAD34159.1|AF153012_1 (AF153012) TGF-beta 2 long form precursor [Rattus norvegicus]
Length = 442
Score = 424 bits (1078), Expect = e-117
Identities = 216/436 (49%), Positives = 276/436 (62%), Gaps = 41/436 (9%)
Query: 14 LLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEP-TVMTHVPYQVLAL 72
LL+ V D +KR+EAIRGQILSKL+LTSPPE VP +V+++
Sbjct: 11 LLHLVPVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPDEVPPEVISI 70
Query: 73 YNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITS--- 129
YNST C +E ++ EYYAKE++K DM VCP TS
Sbjct: 71 YNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPSHFPSE---TVCPVVTTSSGS 127
Query: 130 ----------------------------KVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSS 161
++ RF+VS++EKN +NL +AEFRV R+ NP +
Sbjct: 128 VGSFCSIQSQVLCGYLDAIPPTFYRPYFRIVRFDVSTMEKNASNLVKAEFRVFRLQNPKA 187
Query: 162 KRNEQRIELFQILR-PDEHIAKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLG 220
+ EQRIEL+QIL+ D QRYI K + TR EWLSFDVTD V EWL ++ NLG
Sbjct: 188 RVAEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVHEWLHHKDRNLG 247
Query: 221 LEISIHCPCHTFQP-NGDILENIHEVMEIKFKGVDNEDDHGRGDLGRLK---KQKDHHNP 276
+IS+HCPC TF P N I+ N + +E +F G+D + GD +K K+ P
Sbjct: 248 FKISLHCPCCTFIPSNNYIIPNKSQELEARFAGIDGTSTYASGDQKTIKSTRKKSSGKTP 307
Query: 277 HLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEP 336
HL+LM++P +RL++ Q +R+KRALD YCFRN+++NCC+RPLYIDF++DLGWKW+HEP
Sbjct: 308 HLLLMLLPSYRLESQ-QSSRRRKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEP 366
Query: 337 KGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTP 396
KGY ANFC+G CPYL S+DT H+ VL LYNT+NPEASASPCCV QDLEPLTILYY+G TP
Sbjct: 367 KGYNANFCAGACPYLWSSDTQHTKVLSLYNTINPEASASPCCVSQDLEPLTILYYIGNTP 426
Query: 397 KVEQLSNMVVKSCKCS 412
K+EQLSNM+VKSCKCS
Sbjct: 427 KIEQLSNMIVKSCKCS 442
>sp|P17247|TGF2_XENLA TRANSFORMING GROWTH FACTOR BETA 2 PRECURSOR (TGF-BETA 2)
pir||WFXLB2 transforming growth factor beta-2 precursor - African clawed frog
emb|CAA36116.1| (X51817) prepro-polypeptide [Xenopus laevis]
Length = 413
Score = 422 bits (1074), Expect = e-117
Identities = 214/412 (51%), Positives = 273/412 (65%), Gaps = 12/412 (2%)
Query: 9 LVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMT-HVPY 67
L L+ A V D +KR+EAIRGQILSKL+L SPPE V
Sbjct: 6 LFTFLTLDLAPVALSLSTCSALDMDQFMRKRIEAIRGQILSKLKLNSPPEDYPEPGEVSQ 65
Query: 68 QVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGI 127
V+++YNST C +E +E EYYAKE++K DM+ N V P
Sbjct: 66 DVISIYNSTRDLLQEKANERATSCERERSEDEYYAKEVYKIDMLPYYTSEN---VIPPSY 122
Query: 128 TSKVFR---FNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK-Q 183
T+ FR F+VSS+EKN +NL +AEFRV R+ N ++ +EQRIEL+QIL+ + + Q
Sbjct: 123 TTPYFRIVRFDVSSMEKNASNLVKAEFRVFRLMNTKARVSEQRIELYQILKSKDLASPTQ 182
Query: 184 RYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQP-NGDILENI 242
RYI K + TR EWLSFDVT+ V EWL ++ NLG +IS+HCPC TF P N I+ N
Sbjct: 183 RYIDSKVVKTRAEGEWLSFDVTEAVNEWLHHKDRNLGFKISLHCPCCTFIPSNNYIIPNK 242
Query: 243 HEVMEIKFKGVDNEDDHGRGDLGRLKKQKDH--HNPHLILMMIPPHRLDNPGQGGQRKKR 300
E +E +F G+D+ + GD +K H PHL+LM++P +RL++ Q +RKKR
Sbjct: 243 SEELETRFAGIDDAYMYAGGDSKSKTGRKKHTGRTPHLLLMLLPSYRLESQ-QSSRRKKR 301
Query: 301 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST 360
ALD YCFRN+++NCC+RPLYIDF++DLGWKW+HEPKGY ANFC+G CPYL S+DT HS
Sbjct: 302 ALDAAYCFRNVQDNCCLRPLYIDFKKDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHSR 361
Query: 361 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
VL LYNT+NPEASASPCCV QDL+ LTILYY+G PK+EQLSNM+VKSCKCS
Sbjct: 362 VLSLYNTINPEASASPCCVSQDLDSLTILYYIGNKPKIEQLSNMIVKSCKCS 413
>emb|CAA36117.1| (X51817) pro-TGF-beta2 [Xenopus laevis]
Length = 394
Score = 419 bits (1066), Expect = e-116
Identities = 210/390 (53%), Positives = 268/390 (67%), Gaps = 12/390 (3%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMT-HVPYQVLALYNSTXXXXXXXXXXXXX 89
D +KR+EAIRGQILSKL+L SPPE V V+++YNST
Sbjct: 9 DMDQFMRKRIEAIRGQILSKLKLNSPPEDYPEPGEVSQDVISIYNSTRDLLQEKANERAT 68
Query: 90 XCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFR---FNVSSVEKNRTNL 146
C +E +E EYYAKE++K DM+ N V P T+ FR F+VSS+EKN +NL
Sbjct: 69 SCERERSEDEYYAKEVYKIDMLPYYTSEN---VIPPSYTTPYFRIVRFDVSSMEKNASNL 125
Query: 147 FRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK-QRYIGGKNLPTRGTAEWLSFDVT 205
+AEFRV R+ N ++ +EQRIEL+QIL+ + + QRYI K + TR EWLSFDVT
Sbjct: 126 VKAEFRVFRLMNTKARVSEQRIELYQILKSKDLASPTQRYIDSKVVKTRAEGEWLSFDVT 185
Query: 206 DTVREWLLRRESNLGLEISIHCPCHTFQP-NGDILENIHEVMEIKFKGVDNEDDHGRGDL 264
+ V EWL ++ NLG +IS+HCPC TF P N I+ N E +E +F G+D+ + GD
Sbjct: 186 EAVNEWLHHKDRNLGFKISLHCPCCTFIPSNNYIIPNKSEELETRFAGIDDAYMYAGGDS 245
Query: 265 GRLKKQKDH--HNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYI 322
+K H PHL+LM++P +RL++ Q +RKKRALD YCFRN+++NCC+RPLYI
Sbjct: 246 KSKTGRKKHTGRTPHLLLMLLPSYRLESQ-QSSRRKKRALDAAYCFRNVQDNCCLRPLYI 304
Query: 323 DFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQD 382
DF++DLGWKW+HEPKGY ANFC+G CPYL S+DT HS VL LYNT+NPEASASPCCV QD
Sbjct: 305 DFKKDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQD 364
Query: 383 LEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
L+ LTILYY+G PK+EQLSNM+VKSCKCS
Sbjct: 365 LDSLTILYYIGNKPKIEQLSNMIVKSCKCS 394
>gb|AAG02247.1| (AY007214) transforming growth factor-beta 2 [Mesocricetus auratus]
Length = 399
Score = 417 bits (1060), Expect = e-115
Identities = 205/397 (51%), Positives = 264/397 (65%), Gaps = 7/397 (1%)
Query: 14 LLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEP-TVMTHVPYQVLAL 72
LL+ V D +KR+EAIRGQILSKL+LTSPPE VP +V+++
Sbjct: 4 LLHLVPVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPDEVPPEVISI 63
Query: 73 YNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVF 132
YNST C +E ++ EYYAKE++K DM N + ++
Sbjct: 64 YNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPSHFPSENAIPPTFYRPYFRIV 123
Query: 133 RFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAK-QRYIGGKNL 191
RF+VS +EKN +NL +AEFRV R+ NP ++ EQRIEL+QIL+ + + QRYI K +
Sbjct: 124 RFDVSMMEKNASNLVKAEFRVFRLQNPKARVAEQRIELYQILKSKDLTSPTQRYIDSKVV 183
Query: 192 PTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQP-NGDILENIHEVMEIKF 250
TR EWLSFDVTD V EWL ++ NLG +IS+HCPC TF P N +I+ N E +E +F
Sbjct: 184 KTRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFVPFNNNIIPNKSEELEARF 243
Query: 251 KGVDNEDDHGRGDLGRLK---KQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYC 307
G+D H G +K K+ PHL+LM++P +RL++ Q +RKKRALD YC
Sbjct: 244 AGIDGTSQHSSGHQETIKSTRKKNSGKTPHLLLMLLPSYRLESQ-QSNRRKKRALDAAYC 302
Query: 308 FRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNT 367
FRN+++NCC+RPLYIDF++DLGWKW+HEPKGY ANFC+G CPYL S+DT H+ VL LYNT
Sbjct: 303 FRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHTKVLSLYNT 362
Query: 368 LNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNM 404
+NPEASASPCCV DLEPLTILYY+G TPK+EQLSNM
Sbjct: 363 INPEASASPCCVSHDLEPLTILYYIGNTPKIEQLSNM 399
>gb|AAB62983.1| (U66874) transforming growth factor-beta 2 [Cyprinus carpio]
Length = 361
Score = 384 bits (977), Expect = e-106
Identities = 193/363 (53%), Positives = 248/363 (68%), Gaps = 6/363 (1%)
Query: 46 QILSKLRLTSPPEP-TVMTHVPYQVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKE 104
QIL KL+L+ PPE V ++A+YNST C ++ T EYYAKE
Sbjct: 1 QILCKLKLSCPPEIYPEPEEVSRDIIAIYNSTRDLLQEKANERAATCERQRTGEEYYAKE 60
Query: 105 IHKFDMIQGLAEHNELAVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRN 164
+HK DM N + + RF+VSS+EKN +NL +AE R+ R+ NP ++ +
Sbjct: 61 VHKIDMQPFYPAENVIPTKHYNPYFRRLRFDVSSMEKNASNLVKAELRIFRLQNPKARVS 120
Query: 165 EQRIELFQIL-RPDEHIAKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEI 223
EQRIEL+QIL D QRYI K + TR EWLSFDVT+ V EWLL R+ N G +I
Sbjct: 121 EQRIELYQILGHKDLTSPTQRYIDSKVVRTRTEGEWLSFDVTEAVSEWLLHRDRNNGFKI 180
Query: 224 SIHCPCHTFQP-NGDILENIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDH-HNPHLILM 281
S+HCPC TF P N I+ N E +E +F G+D+ HG GDL KK++ +PHL+LM
Sbjct: 181 SLHCPCCTFVPSNNYIIPNKSEELEARFAGIDDSFVHG-GDLKMFKKRRHSGQSPHLLLM 239
Query: 282 MIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYA 341
++P +RL++ + R+KRALD +CFRN+++NCC+R LYIDF++DLGWKW+HEPKGY A
Sbjct: 240 LLPSYRLESQHKS-HRQKRALDAAFCFRNVQDNCCLRSLYIDFKKDLGWKWIHEPKGYNA 298
Query: 342 NFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQL 401
NFC+G CPYL SADT HS +LGLYNT+NPEASASPCCV QDLEPLTILYY+G+TPK+EQL
Sbjct: 299 NFCAGACPYLWSADTQHSNILGLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQL 358
Query: 402 SNM 404
SNM
Sbjct: 359 SNM 361
>ref|NP_067589.1| transforming growth factor beta-1 gene [Rattus norvegicus]
sp|P17246|TGF1_RAT TRANSFORMING GROWTH FACTOR BETA 1 PRECURSOR (TGF-BETA 1)
pir||S10219 transforming growth factor beta-1 precursor - rat
emb|CAA36741.1| (X52498) prepro-TGF-beta 1 (AA -23 to 367) [Rattus norvegicus]
Length = 390
Score = 311 bits (788), Expect = 1e-83
Identities = 179/388 (46%), Positives = 228/388 (58%), Gaps = 40/388 (10%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTH--VPYQVLALYNSTXXXXXXXXXXXX 88
D +K+KR+EAIRGQILSKLRL SPP + +P VLALYNST
Sbjct: 37 DMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAD-- 94
Query: 89 XXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFRF-NVSSVEKNRTN-- 145
+ E++YYAKE+ + M+ +N + K IT ++ F N S + +
Sbjct: 95 ---PEPEPEADYYAKEVTRVLMVD---RNNAIYDKTKDITHSIYMFFNTSDIREAVPEPP 148
Query: 146 -LFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDV 204
L RAE R+ R + EQ +EL+Q + RY+G + L T EWLSFDV
Sbjct: 149 LLSRAELRLQRFKSTV----EQHVELYQKYSNNSW----RYLGNRLLTPTDTPEWLSFDV 200
Query: 205 TDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDL 264
T VR+WL + + G S HC C ++ V+ ++ G+ + RGDL
Sbjct: 201 TGVVRQWLNQGDGIQGFRFSAHCSC----------DSKDNVLHVEINGISPKR---RGDL 247
Query: 265 GRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDF 324
G + D + P L+LM P R + R +RALDTNYCF + E+NCCVR LYIDF
Sbjct: 248 GTIH---DMNRPFLLLMATPLERAQH--LHSSRHRRALDTNYCFSSTEKNCCVRQLYIDF 302
Query: 325 RQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLE 384
R+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S VL LYN NP ASASPCCVPQ LE
Sbjct: 303 RKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASASPCCVPQALE 362
Query: 385 PLTILYYVGRTPKVEQLSNMVVKSCKCS 412
PL I+YYVGR PKVEQLSNM+V+SCKCS
Sbjct: 363 PLPIVYYVGRKPKVEQLSNMIVRSCKCS 390
>ref|NP_035707.1| transforming growth factor, beta 1; TGF-beta 1 [Mus musculus]
sp|P04202|TGF1_MOUSE TRANSFORMING GROWTH FACTOR BETA 1 PRECURSOR (TGF-BETA 1)
pir||WFMS2 transforming growth factor beta-1 precursor - mouse
gb|AAA40423.1| (M13177) TGF-beta precursor [Mus musculus]
gb|AAB00138.1| (L42462) TGF-1 gene product [Mus musculus]
emb|CAA08900.1| (AJ009862) transforming growth factor-beta 1 [Mus musculus]
Length = 390
Score = 308 bits (781), Expect = 7e-83
Identities = 177/388 (45%), Positives = 228/388 (58%), Gaps = 40/388 (10%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTH--VPYQVLALYNSTXXXXXXXXXXXX 88
D +K+KR+EAIRGQILSKLRL SPP + +P VLALYNST
Sbjct: 37 DMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAD-- 94
Query: 89 XXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFRF-NVSSVEKNRTN-- 145
+ E++YYAKE+ + M+ +N + K I+ ++ F N S + +
Sbjct: 95 ---PEPEPEADYYAKEVTRVLMVD---RNNAIYEKTKDISHSIYMFFNTSDIREAVPEPP 148
Query: 146 -LFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDV 204
L RAE R+ R+ + EQ +EL+Q + RY+G + L T EWLSFDV
Sbjct: 149 LLSRAELRLQRLKSSV----EQHVELYQKYSNNSW----RYLGNRLLTPTDTPEWLSFDV 200
Query: 205 TDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDL 264
T VR+WL + + G S HC C ++ + ++ G+ + RGDL
Sbjct: 201 TGVVRQWLNQGDGIQGFRFSAHCSC----------DSKDNKLHVEINGISPKR---RGDL 247
Query: 265 GRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDF 324
G + D + P L+LM P R + R +RALDTNYCF + E+NCCVR LYIDF
Sbjct: 248 GTIH---DMNRPFLLLMATPLERAQH--LHSSRHRRALDTNYCFSSTEKNCCVRQLYIDF 302
Query: 325 RQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLE 384
R+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S VL LYN NP ASASPCCVPQ LE
Sbjct: 303 RKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASASPCCVPQALE 362
Query: 385 PLTILYYVGRTPKVEQLSNMVVKSCKCS 412
PL I+YYVGR PKVEQLSNM+V+SCKCS
Sbjct: 363 PLPIVYYVGRKPKVEQLSNMIVRSCKCS 390
>pir||A27512 transforming growth factor beta-1 precursor - pig
gb|AAA64616.1| (M23703) transforming growth factor-beta-1 [Sus scrofa]
Length = 390
Score = 307 bits (777), Expect = 2e-82
Identities = 177/388 (45%), Positives = 229/388 (58%), Gaps = 40/388 (10%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTH--VPYQVLALYNSTXXXXXXXXXXXX 88
D +K+KR+EAIRGQILSKLRL SPP + +P VLALYNST
Sbjct: 37 DMELVKRKRIEAIRGQILSKLRLASPPSQGDVPPGPLPEAVLALYNSTRDRVAGESVE-- 94
Query: 89 XXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFR-FNVSSVEK---NRT 144
+ E++YYAKE+ + M++ N++ KG ++ FN S + +
Sbjct: 95 ---PEPEPEADYYAKEVTRVLMVES---GNQIYDKFKGTPHSLYMLFNTSELREAVPEPV 148
Query: 145 NLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDV 204
L RAE R+LR+ + EQ +EL+Q D RY+ + L + EWLSFDV
Sbjct: 149 LLSRAELRLLRL----KLKVEQHVELYQKYSNDSW----RYLSNRLLAPSDSPEWLSFDV 200
Query: 205 TDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDL 264
T VR+WL RRE+ G +S HC C ++ + ++ G ++ RGDL
Sbjct: 201 TGVVRQWLTRREAIEGFRLSAHCSC----------DSKDNTLHVEINGFNSGR---RGDL 247
Query: 265 GRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDF 324
+ + P L+LM P R + R +RALDTNYCF + E+NCCVR LYIDF
Sbjct: 248 ATIHGM---NRPFLLLMATPLERAQH--LHSSRHRRALDTNYCFSSTEKNCCVRQLYIDF 302
Query: 325 RQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLE 384
R+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S VL LYN NP ASA+PCCVPQ LE
Sbjct: 303 RKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALE 362
Query: 385 PLTILYYVGRTPKVEQLSNMVVKSCKCS 412
PL I+YYVGR PKVEQLSNM+V+SCKCS
Sbjct: 363 PLPIVYYVGRKPKVEQLSNMIVRSCKCS 390
>sp|P07200|TGF1_PIG TRANSFORMING GROWTH FACTOR BETA 1 PRECURSOR (TGF-BETA 1)
emb|CAA68291.1| (Y00111) TFG-beta precursor (AA 1-390) [Sus scrofa]
Length = 390
Score = 306 bits (776), Expect = 3e-82
Identities = 177/388 (45%), Positives = 229/388 (58%), Gaps = 40/388 (10%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTH--VPYQVLALYNSTXXXXXXXXXXXX 88
D +K+KR+EAIRGQILSKLRL SPP + +P VLALYNST
Sbjct: 37 DMELVKRKRIEAIRGQILSKLRLASPPSQGDVPPGPLPEAVLALYNSTRDRVAGESVE-- 94
Query: 89 XXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFR-FNVSSVEK---NRT 144
+ E++YYAKE+ + M++ N++ KG ++ FN S + +
Sbjct: 95 ---PEPEPEADYYAKEVTRVLMLES---GNQIYDKFKGTPHSLYMLFNTSELREAVPEPV 148
Query: 145 NLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDV 204
L RAE R+LR+ + EQ +EL+Q D RY+ + L + EWLSFDV
Sbjct: 149 LLSRAELRLLRL----KLKVEQHVELYQKYSNDSW----RYLSNRLLAPSDSPEWLSFDV 200
Query: 205 TDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDL 264
T VR+WL RRE+ G +S HC C ++ + ++ G ++ RGDL
Sbjct: 201 TGVVRQWLTRREAIEGFRLSAHCSC----------DSKDNTLHVEINGFNSGR---RGDL 247
Query: 265 GRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDF 324
+ + P L+LM P R + R +RALDTNYCF + E+NCCVR LYIDF
Sbjct: 248 ATIHGM---NRPFLLLMATPLERAQH--LHSSRHRRALDTNYCFSSTEKNCCVRQLYIDF 302
Query: 325 RQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLE 384
R+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S VL LYN NP ASA+PCCVPQ LE
Sbjct: 303 RKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALE 362
Query: 385 PLTILYYVGRTPKVEQLSNMVVKSCKCS 412
PL I+YYVGR PKVEQLSNM+V+SCKCS
Sbjct: 363 PLPIVYYVGRKPKVEQLSNMIVRSCKCS 390
>sp|P54831|TGF1_CANFA TRANSFORMING GROWTH FACTOR BETA 1 PRECURSOR (TGF-BETA 1)
pir||JC4023 transforming growth factor beta-1 - dog
gb|AAA51458.1| (L34956) transforming growth factor-beta 1 [Canis familiaris]
Length = 390
Score = 304 bits (770), Expect = 1e-81
Identities = 176/387 (45%), Positives = 223/387 (57%), Gaps = 38/387 (9%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTHVPYQ--VLALYNSTXXXXXXXXXXXX 88
D +K+KR+EAIRGQILSKLRL+SPP + VP VLALYNST
Sbjct: 37 DMELVKRKRIEAIRGQILSKLRLSSPPSQGEVPPVPLPEAVLALYNSTRDRVAGESAE-- 94
Query: 89 XXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFRFNVSSVEK---NRTN 145
+ E++YYAKE+ + M++ + E K S FN S + +
Sbjct: 95 ---PEPEPEADYYAKEVTRVLMVENTNKIYEKV--KKSPHSIYMLFNTSELREAVPEPVL 149
Query: 146 LFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDVT 205
L RAE R+LR+ + EQ +EL+Q D RY+ + L T EWLSFDVT
Sbjct: 150 LSRAELRLLRL----KLKAEQHVELYQKYSNDSW----RYLSNRLLAPSDTPEWLSFDVT 201
Query: 206 DTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDLG 265
VR+WL G +S HC C ++ +++ G + RGDL
Sbjct: 202 GVVRQWLSHGGEVEGFRLSAHCSC----------DSKDNTLQVDINGFSSSR---RGDLA 248
Query: 266 RLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDFR 325
+ + P L+LM P R + R++RALDTNYCF + E+NCCVR LYIDFR
Sbjct: 249 TIHGM---NRPFLLLMATPLERAQH--LHSSRQRRALDTNYCFSSTEKNCCVRQLYIDFR 303
Query: 326 QDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEP 385
+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S VL LYN NP ASA+PCCVPQ LEP
Sbjct: 304 KDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEP 363
Query: 386 LTILYYVGRTPKVEQLSNMVVKSCKCS 412
L I+YYVGR PKVEQLSNM+V+SCKCS
Sbjct: 364 LPIVYYVGRKPKVEQLSNMIVRSCKCS 390
>gb|AAD49431.1| (AF175709) transforming growth factor beta 1 [Equus caballus]
Length = 390
Score = 303 bits (768), Expect = 2e-81
Identities = 179/388 (46%), Positives = 225/388 (57%), Gaps = 40/388 (10%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTH--VPYQVLALYNSTXXXXXXXXXXXX 88
D +K+KR+EAIRGQILSKLRL SPP + +P VLALYNST
Sbjct: 37 DMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRAQVAGESAE-- 94
Query: 89 XXCTQENTESEYYAKEIHKFDMIQGLAEHNEL-AVCPKGITSKVFRFNVSSVEKNRTN-- 145
T+ E++YYAKE+ + M++ + NE+ G S FN S + +
Sbjct: 95 ---TEPEPEADYYAKEVTRVLMVE---KENEIYKTVETGSHSIYMFFNASELRAAVPDPM 148
Query: 146 -LFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDV 204
L RAE R+LR+ EQ +EL+Q + RY+ + L + EWLSFDV
Sbjct: 149 LLSRAELRLLRL----KLSVEQHVELYQKYSNNSW----RYLSNRLLTPSDSPEWLSFDV 200
Query: 205 TDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDL 264
T VR+WL + + GL +S HCPC D +N V G++ RGDL
Sbjct: 201 TGVVRQWLSQGGAMEGLRLSAHCPC-------DSKDNTLRV------GINGFSSSRRGDL 247
Query: 265 GRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDF 324
+ + P L+LM P R R +RALDTNYC + E+NCCVR LYIDF
Sbjct: 248 ATIDGM---NRPFLLLMATPLERAQQ--LHSSRHRRALDTNYCSSSTEKNCCVRQLYIDF 302
Query: 325 RQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLE 384
R+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S VL LYN NP ASA+PCCVPQ LE
Sbjct: 303 RKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQVLE 362
Query: 385 PLTILYYVGRTPKVEQLSNMVVKSCKCS 412
PL I+YYVGR PKVEQLSNM+V+SCKCS
Sbjct: 363 PLPIVYYVGRKPKVEQLSNMIVRSCKCS 390
>sp|P01137|TGF1_HUMAN TRANSFORMING GROWTH FACTOR BETA 1 PRECURSOR (TGF-BETA 1)
pir||WFHU2 transforming growth factor beta-1 precursor - human
emb|CAA29283.1| (X05839) transforming growth factor beta 1 precursor [Homo sapiens]
Length = 390
Score = 303 bits (767), Expect = 3e-81
Identities = 178/388 (45%), Positives = 226/388 (57%), Gaps = 40/388 (10%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTH--VPYQVLALYNSTXXXXXXXXXXXX 88
D +K+KR+EAIRGQILSKLRL SPP + +P VLALYNST
Sbjct: 37 DMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAE-- 94
Query: 89 XXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFRF-NVSSVEK---NRT 144
+ E++YYAKE+ + M++ HNE+ K T ++ F N S + +
Sbjct: 95 ---PEPEPEADYYAKEVTRVLMVE---THNEIYDKFKQSTHSIYMFFNTSELREAVPEPV 148
Query: 145 NLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDV 204
L RAE R+LR+ + EQ +EL+Q + RY+ + L + EWLSFDV
Sbjct: 149 LLSRAELRLLRL----KLKVEQHVELYQKYSNNSW----RYLSNRLLAPSDSPEWLSFDV 200
Query: 205 TDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDL 264
T VR+WL R G +S HC C D +N +V ++ RGDL
Sbjct: 201 TGVVRQWLSRGGEIEGFRLSAHCSC-------DSRDNTLQV------DINGFTTGRRGDL 247
Query: 265 GRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDF 324
+ + P L+LM P R + R +RALDTNYCF + E+NCCVR LYIDF
Sbjct: 248 ATIHGM---NRPFLLLMATPLERAQH--LQSSRHRRALDTNYCFSSTEKNCCVRQLYIDF 302
Query: 325 RQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLE 384
R+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S VL LYN NP ASA+PCCVPQ LE
Sbjct: 303 RKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALE 362
Query: 385 PLTILYYVGRTPKVEQLSNMVVKSCKCS 412
PL I+YYVGR PKVEQLSNM+V+SCKCS
Sbjct: 363 PLPIVYYVGRKPKVEQLSNMIVRSCKCS 390
>pir||S01413 transforming growth factor beta-1 precursor - chicken
emb|CAA30933.1| (X12373) transforming growth factor [Sus scrofa]
Length = 391
Score = 303 bits (767), Expect = 3e-81
Identities = 177/388 (45%), Positives = 226/388 (57%), Gaps = 39/388 (10%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTH--VPYQVLALYNSTXXXXXXXXXXXX 88
D +K+KR+EAIRGQILSKLRL SPP + +P VLALYNST
Sbjct: 37 DMELVKRKRIEAIRGQILSKLRLASPPSQGDVPPGPLPEAVLALYNSTRDRVAGESVE-- 94
Query: 89 XXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFR-FNVSSVEK---NRT 144
+ E++YYAKE+ + M++ N++ KG ++ FN S + +
Sbjct: 95 ---PEPEPEADYYAKEVTRVLMVES---GNQIYDKFKGTPHSLYMLFNTSELREAVPEPV 148
Query: 145 NLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDV 204
L RAE R+LR+ + EQ +EL+Q D Y+ + L + EWLSFDV
Sbjct: 149 LLSRAELRLLRL----KLKVEQHVELYQKYSNDSW----GYLSNRLLAPSDSPEWLSFDV 200
Query: 205 TDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDL 264
T VR+WL RRE+ G +S HC C + +H + F + RGDL
Sbjct: 201 TGVVRQWLTRREAIEGFRLSAHCSCDSKD------NTLHVEINAGF------NSGRRGDL 248
Query: 265 GRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDF 324
+ + P L+LM P R + R +RALDTNYCF + E+NCCVR LYIDF
Sbjct: 249 ATIHGM---NRPFLLLMATPLERAQH--LHSSRHRRALDTNYCFSSTEKNCCVRQLYIDF 303
Query: 325 RQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLE 384
R+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S VL LYN NP ASA+PCCVPQ LE
Sbjct: 304 RKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALE 363
Query: 385 PLTILYYVGRTPKVEQLSNMVVKSCKCS 412
PL I+YYVGR PKVEQLSNM+V+SCKCS
Sbjct: 364 PLPIVYYVGRKPKVEQLSNMIVRSCKCS 391
>sp|O19011|TGF1_HORSE TRANSFORMING GROWTH FACTOR BETA 1 PRECURSOR (TGF-BETA 1)
emb|CAA67801.1| (X99438) transforming growth factor-beta 1 [Equus caballus]
Length = 390
Score = 302 bits (764), Expect = 7e-81
Identities = 178/388 (45%), Positives = 224/388 (56%), Gaps = 40/388 (10%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTH--VPYQVLALYNSTXXXXXXXXXXXX 88
D +K+KR+EAIRGQILSKLRL SPP + +P VLALYNST
Sbjct: 37 DMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRAQVAGESAE-- 94
Query: 89 XXCTQENTESEYYAKEIHKFDMIQGLAEHNEL-AVCPKGITSKVFRFNVSSVEKNRTN-- 145
T+ E++YYAKE+ + M++ + NE+ G S FN S + +
Sbjct: 95 ---TEPEPEADYYAKEVTRVLMVE---KENEIYKTVETGSHSIYMFFNTSELRAAVPDPM 148
Query: 146 -LFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDV 204
L RAE R+LR+ EQ +EL+Q + RY+ + L + EWLSFDV
Sbjct: 149 LLSRAELRLLRL----KLSVEQHVELYQKYSNNSW----RYLSNRLLTPSDSPEWLSFDV 200
Query: 205 TDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDL 264
T VR+WL + + G +S HC C D +N V G++ RGDL
Sbjct: 201 TGVVRQWLSQGGAMEGFRLSAHCSC-------DSKDNTLRV------GINGFSSSRRGDL 247
Query: 265 GRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDF 324
+ + P L+LM P R R +RALDTNYCF + E+NCCVR LYIDF
Sbjct: 248 ATIDGM---NRPFLLLMATPLERAQQ--LHSSRHRRALDTNYCFSSTEKNCCVRQLYIDF 302
Query: 325 RQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLE 384
R+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S VL LYN NP ASA+PCCVPQ LE
Sbjct: 303 RKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQVLE 362
Query: 385 PLTILYYVGRTPKVEQLSNMVVKSCKCS 412
PL I+YYVGR PKVEQLSNM+V+SCKCS
Sbjct: 363 PLPIVYYVGRKPKVEQLSNMIVRSCKCS 390
>sp|P09533|TGF1_CERAE TRANSFORMING GROWTH FACTOR BETA 1 PRECURSOR (TGF-BETA 1)
pir||A26960 transforming growth factor beta-1 precursor - green monkey
gb|AAA35369.1| (M16658) transforming growth factor-beta precursor [Cercopithecus
aethiops]
Length = 390
Score = 302 bits (764), Expect = 7e-81
Identities = 177/388 (45%), Positives = 225/388 (57%), Gaps = 40/388 (10%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTH--VPYQVLALYNSTXXXXXXXXXXXX 88
D +K+KR+E IRGQILSKLRL SPP + +P VLALYNST
Sbjct: 37 DMELVKRKRIETIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAE-- 94
Query: 89 XXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFRF-NVSSVEK---NRT 144
+ E++YYAKE+ + M++ HNE+ K T ++ F N S + +
Sbjct: 95 ---PEPEPEADYYAKEVTRVLMVE---THNEIYDKFKQSTHSIYMFFNTSELREAVPEPV 148
Query: 145 NLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDV 204
L RAE R+LR+ + EQ +EL+Q + RY+ + L + EWLSFDV
Sbjct: 149 LLSRAELRLLRL----KLKVEQHVELYQKYSNNSW----RYLSNRLLAPSNSPEWLSFDV 200
Query: 205 TDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDL 264
T VR+WL R G +S HC C D +N +V ++ RGDL
Sbjct: 201 TGVVRQWLSRGGEIEGFRLSAHCSC-------DSKDNTLQV------DINGFTTGRRGDL 247
Query: 265 GRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDF 324
+ + P L+LM P R + R +RALDTNYCF + E+NCCVR LYIDF
Sbjct: 248 ATIHGM---NRPFLLLMATPLERAQH--LQSSRHRRALDTNYCFSSTEKNCCVRQLYIDF 302
Query: 325 RQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLE 384
R+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S VL LYN NP ASA+PCCVPQ LE
Sbjct: 303 RKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALE 362
Query: 385 PLTILYYVGRTPKVEQLSNMVVKSCKCS 412
PL I+YYVGR PKVEQLSNM+V+SCKCS
Sbjct: 363 PLPIVYYVGRKPKVEQLSNMIVRSCKCS 390
>ref|NP_000651.1| transforming growth factor, beta 1; diaphyseal dysplasia 1,
progressive (Camurati-Engelmann disease) [Homo sapiens]
emb|CAA26580.1| (X02812) TGF-beta precursor [Homo sapiens]
prf||1109243A transforming growth factor beta [Homo sapiens]
Length = 391
Score = 301 bits (763), Expect = 9e-81
Identities = 178/388 (45%), Positives = 225/388 (57%), Gaps = 39/388 (10%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTH--VPYQVLALYNSTXXXXXXXXXXXX 88
D +K+KR+EAIRGQILSKLRL SPP + +P VLALYNST
Sbjct: 37 DMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAE-- 94
Query: 89 XXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFRF-NVSSVEK---NRT 144
+ E++YYAKE+ + M++ HNE+ K T ++ F N S + +
Sbjct: 95 ---PEPEPEADYYAKEVTRVLMVE---THNEIYDKFKQSTHSIYMFFNTSELREAVPEPV 148
Query: 145 NLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDV 204
L RAE R+LR + EQ +EL+Q + RY+ + L + EWLSFDV
Sbjct: 149 LLSRAELRLLR---RLKLKVEQHVELYQKYSNNSW----RYLSNRLLAPSDSPEWLSFDV 201
Query: 205 TDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDL 264
T VR+WL R G +S HC C D +N +V ++ RGDL
Sbjct: 202 TGVVRQWLSRGGEIEGFRLSAHCSC-------DSRDNTLQV------DINGFTTGRRGDL 248
Query: 265 GRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDF 324
+ + P L+LM P R + R +RALDTNYCF + E+NCCVR LYIDF
Sbjct: 249 ATIHGM---NRPFLLLMATPLERAQH--LQSSRHRRALDTNYCFSSTEKNCCVRQLYIDF 303
Query: 325 RQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLE 384
R+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S VL LYN NP ASA+PCCVPQ LE
Sbjct: 304 RKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALE 363
Query: 385 PLTILYYVGRTPKVEQLSNMVVKSCKCS 412
PL I+YYVGR PKVEQLSNM+V+SCKCS
Sbjct: 364 PLPIVYYVGRKPKVEQLSNMIVRSCKCS 391
>sp|P50414|TGF1_SHEEP TRANSFORMING GROWTH FACTOR BETA 1 PRECURSOR (TGF-BETA 1)
pir||S45115 transforming growth factor-beta 1 - sheep
pir||I46463 transforming growth factor beta-1 - sheep
emb|CAA54242.1| (X76916) transforming growth factor-beta 1 [Ovis aries]
Length = 390
Score = 299 bits (757), Expect = 4e-80
Identities = 174/388 (44%), Positives = 226/388 (57%), Gaps = 40/388 (10%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTH--VPYQVLALYNSTXXXXXXXXXXXX 88
D +K+K +EAIRGQILSKLRL SPP + +P +LALYNST
Sbjct: 37 DMELVKRKGIEAIRGQILSKLRLASPPSQGDVPPGPLPEAILALYNSTRDRVAGESAE-- 94
Query: 89 XXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFRF-NVSSVEK---NRT 144
T+ E++YYAKE+ + M++ N++ K + ++ F N S + +
Sbjct: 95 ---TEPEPEADYYAKEVTRVLMVE---YGNKIYDKMKSSSHSIYMFFNTSELREAVPEPV 148
Query: 145 NLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDV 204
L RA+ R+LR+ + EQ +EL+Q + RY+ + L + EWLSFDV
Sbjct: 149 LLSRADVRLLRL----KLKVEQHVELYQKYSNNSW----RYLSNRLLAPSDSPEWLSFDV 200
Query: 205 TDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDL 264
T VR+WL RE G +S HC C D +N +V ++ RGDL
Sbjct: 201 TGVVRQWLTHREEIEGFRLSAHCSC-------DSKDNTLQV------DINGFSSGRRGDL 247
Query: 265 GRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDF 324
+ + P L+LM P R + R +RALDTNYCF + E+NCCVR LYIDF
Sbjct: 248 ATIHGM---NRPFLLLMATPLERAQH--LHSSRHRRALDTNYCFSSTEKNCCVRQLYIDF 302
Query: 325 RQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLE 384
R+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S VL LYN NP ASA+PCCVPQ LE
Sbjct: 303 RKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALE 362
Query: 385 PLTILYYVGRTPKVEQLSNMVVKSCKCS 412
PL I+YYVGR PKVEQLSNM+V+SCKCS
Sbjct: 363 PLPIVYYVGRKPKVEQLSNMIVRSCKCS 390
>gb|AAF02780.1|AF191297_1 (AF191297) transforming growth factor-beta [Cavia porcellus]
Length = 390
Score = 293 bits (741), Expect = 3e-78
Identities = 174/388 (44%), Positives = 219/388 (55%), Gaps = 40/388 (10%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVMTH--VPYQVLALYNSTXXXXXXXXXXXX 88
D +K+KR+EAIRGQILSKLRL SPP + +P VLALYNST
Sbjct: 37 DMELVKRKRIEAIRGQILSKLRLASPPSQGDVPPGPLPEAVLALYNSTRDRVAGESAE-- 94
Query: 89 XXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFRFNVSSVEKNRTN--- 145
+ E +YYAKE+ + M+ HN S FN S + + +
Sbjct: 95 ---PEPEPEPDYYAKEVTRVLMVDN--SHNIYKSIETVAHSIYMFFNTSELREAVPDPLL 149
Query: 146 LFRAEFRVLRVPNPSSKRN-EQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDV 204
L RAE R+ R+ K N EQ +EL+Q + RY+ + L T EWLSFDV
Sbjct: 150 LSRAELRMQRL-----KLNVEQHVELYQKYSNNSW----RYLSNQLLTPSDTPEWLSFDV 200
Query: 205 TDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDL 264
T VR+WL + E G S HC C ++ + ++ G+ + RGDL
Sbjct: 201 TGVVRQWLSQGEELEGFRFSAHCSC----------DSKDNTLRVEINGIGPKR---RGDL 247
Query: 265 GRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDF 324
+ + P L+LM P R + R +R LDTNYCF + E+NCCVR LYIDF
Sbjct: 248 AAIHGM---NRPFLLLMATPLERAQH--LHSSRHRRGLDTNYCFSSTEKNCCVRQLYIDF 302
Query: 325 RQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLE 384
R+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S VL LYN NP ASA+PCCVPQ LE
Sbjct: 303 RKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALE 362
Query: 385 PLTILYYVGRTPKVEQLSNMVVKSCKCS 412
PL I+YYVGR KVEQLSNM+V+SCKCS
Sbjct: 363 PLPIVYYVGRKAKVEQLSNMIVRSCKCS 390
>sp|P09531|TGF1_CHICK TRANSFORMING GROWTH FACTOR BETA 1 PRECURSOR (TGF-BETA 1) (TGF-BETA
4)
pir||A41918 transforming growth factor beta-4 precursor - chicken (fragment)
gb|AAB05637.1| (M31160) transforming growth factor beta 4 precursor [Gallus
gallus]
Length = 373
Score = 292 bits (740), Expect = 4e-78
Identities = 178/392 (45%), Positives = 227/392 (57%), Gaps = 37/392 (9%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPP--EPTVMTHVPYQVLALYNSTXXXXXXXXXXXX 88
D KKKR+EA+RGQILSKLRLT+PP T +P V ALYNST
Sbjct: 9 DLEAAKKKRIEAVRGQILSKLRLTAPPPASETPPRPLPDDVRALYNSTQELLKQRARLR- 67
Query: 89 XXCTQENTESEYYAKEIHKFDMI---QGLAEHNELAVCPKGITSKVFRFNVSSVEKNR-- 143
+ EY+AKE+ + M G EH + P+ S F FNVS +
Sbjct: 68 ---PPPDGPDEYWAKELRRIPMETTWDGAMEHWQ----PQS-HSIFFVFNVSRARRGGRP 119
Query: 144 TNLFRAEFRVLRVPNPS-SKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSF 202
T L RAE R+LR + S EQR+EL+Q A RY+ G+++ EWLSF
Sbjct: 120 TLLHRAELRMLRQKAAADSAGTEQRLELYQ----GYGNASWRYLHGRSVRATADDEWLSF 175
Query: 203 DVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRG 262
DVTD V +WL E ++S+HCPC + E M I +G + + RG
Sbjct: 176 DVTDAVHQWLSGSELLGVFKLSVHCPCEMGPGHA-------EEMRISIEGFEQQ----RG 224
Query: 263 DLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFR--NLEENCCVRPL 320
D+ + K K P+++ M +P R + R++R LDT+YCF E+NCCVRPL
Sbjct: 225 DMQSIAK-KHRRVPYVLAMALPAERANELHSA--RRRRDLDTDYCFGPGTDEKNCCVRPL 281
Query: 321 YIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVP 380
YIDFR+DL WKW+HEPKGY ANFC GPCPY+ SADT ++ VL LYN NP ASA+PCCVP
Sbjct: 282 YIDFRKDLQWKWIHEPKGYMANFCMGPCPYIWSADTQYTKVLALYNQHNPGASAAPCCVP 341
Query: 381 QDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
Q L+PL I+YYVGR +VEQLSNMVV++CKCS
Sbjct: 342 QTLDPLPIIYYVGRNVRVEQLSNMVVRACKCS 373
>sp|P16176|TGF1_XENLA TRANSFORMING GROWTH FACTOR BETA 1 PRECURSOR (TGF-BETA 1) (TGF-BETA
5)
pir||B61036 transforming growth factor beta-5 precursor - African clawed frog
gb|AAA49968.1| (J05180) transforming growth factor-beta (TGF-beta 5) precursor
[Xenopus laevis]
gb|AAB64441.1| (AF009335) transforming growth factor-beta5 [Xenopus laevis]
Length = 382
Score = 290 bits (735), Expect = 2e-77
Identities = 166/408 (40%), Positives = 222/408 (53%), Gaps = 36/408 (8%)
Query: 9 LVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPE-PTVMTHVPY 67
L+VL +L+ +++ D ++K+R+EAIRGQILSKL+L P+ + VP
Sbjct: 7 LLVLLVLHLSSLAMSLSTCKAVDMEEVRKRRIEAIRGQILSKLKLDKTPDVDSEKMTVPS 66
Query: 68 QVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGI 127
+ + LYNST + +YYAK++++F+ I L +H
Sbjct: 67 EAIFLYNSTLEVIREKATREEEHVGHDQNIQDYYAKQVYRFESITELEDHEFK------- 119
Query: 128 TSKVFRFNVSSVEKN---RTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQR 184
F+FN S V +N + L AE R+ + + K +QR+ELF + + R
Sbjct: 120 ----FKFNASHVRENVGMNSLLHHAELRMYK--KQTDKNMDQRMELFWKYQ-ENGTTHSR 172
Query: 185 YIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHE 244
Y+ K + EW+SFDVT TV EWL R E N + C C T Q +E
Sbjct: 173 YLESKYITPVTDDEWMSFDVTKTVNEWLKRAEENEQFGLQPACKCPTPQAKDIDIEGFPA 232
Query: 245 VMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDT 304
+ RGDL L K++ P+L++ +P R+D RKKR +
Sbjct: 233 L---------------RGDLASLSS-KENTKPYLMITSMPAERIDTVTSS--RKKRGVGQ 274
Query: 305 NYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGL 364
YCF N NCCV+PLYI+FR+DLGWKW+HEPKGY AN+C G CPY+ S DT +S VL L
Sbjct: 275 EYCFGNNGPNCCVKPLYINFRKDLGWKWIHEPKGYEANYCLGNCPYIWSMDTQYSKVLSL 334
Query: 365 YNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
YN NP AS SPCCVP LEPL I+YYVGRT KVEQLSNMVV+SC CS
Sbjct: 335 YNQNNPGASISPCCVPDVLEPLPIIYYVGRTAKVEQLSNMVVRSCNCS 382
>sp|P18341|TGF1_BOVIN TRANSFORMING GROWTH FACTOR BETA 1 PRECURSOR (TGF-BETA 1)
pir||A40057 transforming growth factor beta-1 precursor - bovine (fragment)
gb|AAA30778.1| (M36271) transforming growth factor-beta-1 precursor [Bos taurus]
Length = 315
Score = 270 bits (684), Expect = 2e-71
Identities = 155/348 (44%), Positives = 202/348 (57%), Gaps = 38/348 (10%)
Query: 69 VLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGIT 128
+LALYNST T+ E++YYAKE+ + M++ N++ K +
Sbjct: 2 ILALYNSTRDRVAGESAE-----TEPEPEADYYAKEVTRVLMVE---YGNKIYDKMKSSS 53
Query: 129 SKVFRF-NVSSVEK---NRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQR 184
++ F N S + + L RA+ R+LR+ + EQ +EL+Q + R
Sbjct: 54 HSIYMFFNTSELREAVPEPVLLSRADVRLLRL----KLKVEQHVELYQKYSNNSW----R 105
Query: 185 YIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHE 244
Y+ + L + EWLSFDVT VR+WL RRE G +S HC C D +N +
Sbjct: 106 YLSNRLLAPSDSPEWLSFDVTGVVRQWLTRREEIEGFRLSAHCSC-------DSKDNTLQ 158
Query: 245 VMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDT 304
V ++ RGDL + + P L+LM P R + R +RALDT
Sbjct: 159 V------DINGFSSGRRGDLATIHGM---NRPFLLLMATPLERAQH--LHSSRHRRALDT 207
Query: 305 NYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGL 364
NYCF + E+NCCVR LYIDFR+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S VL L
Sbjct: 208 NYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLAL 267
Query: 365 YNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
YN NP ASA+PCCVPQ LEPL I+YYVGR PKVEQLSNM+V+SCKCS
Sbjct: 268 YNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS 315
>gb|AAD46997.1|AF140363_1 (AF140363) transforming growth factor-beta precursor [Morone
chrysops x Morone saxatilis]
Length = 382
Score = 266 bits (672), Expect = 4e-70
Identities = 160/388 (41%), Positives = 213/388 (54%), Gaps = 38/388 (9%)
Query: 31 DFGHIKKKRVEAIRGQILSKLRLTSPPEPTVM---THVPYQVLALYNSTXXXXXXXXXXX 87
D +KKKR+EAIR QILSKLRL PEP +P +L+LYNST
Sbjct: 27 DLEMVKKKRIEAIRSQILSKLRLPKEPEPDQAGDEEEIPTPLLSLYNSTKEMLKEQQTEV 86
Query: 88 XXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPKGITSKVFRFNVSSVEKNRTN-- 145
+ E E EY+AK +HKF+M + ++N T K+F FN+S + ++ +
Sbjct: 87 QTDISTEQEEEEYFAKVLHKFNMTR---KNNT------DTTKKMF-FNISEIRESVGDYR 136
Query: 146 -LFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDV 204
L AE R+L ++ +EQR+EL+ L RY+ + + + +WLSFDV
Sbjct: 137 LLTSAELRMLI--KKTTIYDEQRVELYSGLGDSP-----RYLASRFITNKWKDKWLSFDV 189
Query: 205 TDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDL 264
T T+++WL + G ++ + C C+ I FK + D GRGD
Sbjct: 190 TKTLQDWLKGTDDEQGFQLRLFCECNKVSAGETI-----------FKFGISGIDPGRGDT 238
Query: 265 GRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDF 324
G + Q P IL M P + +P RKKR+ +T E CCVR LYIDF
Sbjct: 239 GPM--QLLTQQPPYILTMSIPQNISSPSTS--RKKRSTETKDVCTAQTETCCVRSLYIDF 294
Query: 325 RQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLE 384
R+DLGWKW+H+P GY AN+C G C Y+ +A+ +S +L LY NP ASA PCCVPQ LE
Sbjct: 295 RKDLGWKWIHKPTGYNANYCMGSCTYIWNAENKYSQILALYKHHNPGASAQPCCVPQALE 354
Query: 385 PLTILYYVGRTPKVEQLSNMVVKSCKCS 412
PL ILYYVGR KVEQLSNM+VKSCKCS
Sbjct: 355 PLPILYYVGRQHKVEQLSNMIVKSCKCS 382
>emb|CAA07707.1| (AJ007836) transforming growth factor-beta [Oncorhynchus mykiss]
Length = 382
Score = 257 bits (649), Expect = 2e-67
Identities = 161/412 (39%), Positives = 213/412 (51%), Gaps = 45/412 (10%)
Query: 9 LVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPEPTV-----MT 63
L L +L + D +K+KR+EAIRGQILSKLRL P EP +
Sbjct: 8 LTALLMLEYVCRSDTMSTCKSLDLELVKRKRIEAIRGQILSKLRL--PKEPEIDQEGDTE 65
Query: 64 HVPYQVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVC 123
VP ++++YNST TQ+ E Y+AKE+HKF+M Q
Sbjct: 66 EVPASLMSIYNSTVELSEEQVHTYIPS-TQDAEEEAYFAKEVHKFNMKQS---------- 114
Query: 124 PKGITSKVFRFNVS---SVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHI 180
+ + FN+S SV L +AE R+L + +EQR+EL++ +
Sbjct: 115 -ENTSKHQILFNMSEMRSVLGTDRLLSQAELRLLIKNHGLLDDSEQRLELYRGVGD---- 169
Query: 181 AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE 240
K RY+ + W+SFDVT T+ EWL G ++ + C C G +E
Sbjct: 170 -KARYLKSHFVSKEWANRWVSFDVTQTLNEWLQGAGEEQGFQLKLPCDC------GKPME 222
Query: 241 NIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR 300
K G++ RG+ L K PH++LM +P R Q RKKR
Sbjct: 223 EFR----FKISGMNKL----RGNTETLA-MKMPSKPHILLMSLPVER---HSQLSSRKKR 270
Query: 301 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST 360
T + E+CCVR LYIDFR+DLGWKW+HEP GY+AN+C GPC Y+ + + +S
Sbjct: 271 QTTTEEICSDKSESCCVRKLYIDFRKDLGWKWIHEPTGYFANYCIGPCTYIWNTENKYSQ 330
Query: 361 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
VL LY NP ASA PCCVPQ LEPL I+YYVGR KVEQLSNM+VKSC+CS
Sbjct: 331 VLALYKHHNPGASAQPCCVPQVLEPLPIIYYVGRQHKVEQLSNMIVKSCRCS 382
>gb|AAF22573.1|AF136947_1 (AF136947) transforming growth factor beta 1 [Cyprinus carpio]
Length = 376
Score = 253 bits (639), Expect = 3e-66
Identities = 155/410 (37%), Positives = 219/410 (52%), Gaps = 49/410 (11%)
Query: 9 LVVLALLNFATVXXXXXXXXXXDFGHIKKKRVEAIRGQILSKLRLTSPPE---PTVMTHV 65
L + LL F D IK+KR+EAIRGQILSKLRL+ PE ++
Sbjct: 8 LALQCLLGFVHYSGALSTCSPLDLELIKRKRIEAIRGQILSKLRLSKEPEVDEEKESQNI 67
Query: 66 PYQVLALYNSTXXXXXXXXXXXXXXCTQENTESEYYAKEIHKFDMIQGLAEHNELAVCPK 125
P +++++YNST ++ E EYYAKE+HKF + L E N
Sbjct: 68 PAELISVYNSTVELNEEQAAPPEQP-KEDPVEEEYYAKEVHKFTI--KLMEKNP------ 118
Query: 126 GITSKVFRFNVSSVEK----NRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHIA 181
K FN++ + + NR + + E R+L P +EQR+EL+Q++
Sbjct: 119 ---DKFLWFNITDISQTLGLNRI-ISQVELRLLITTFPDG--SEQRLELYQVIGN----- 167
Query: 182 KQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILEN 241
K RY+ + +P + +WLSFDVT T+++WL R E+ G ++ + C
Sbjct: 168 KSRYLESRFIPNQ--RKWLSFDVTQTLKDWLQRSEAEQGFQLKMADNCDP---------- 215
Query: 242 IHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRA 301
+ ++K G+ RGD L PH+++M +P LD R+KR
Sbjct: 216 -QKTFQLKIPGLVLV----RGDTETLAVNMPR--PHILVMSLP---LDGNNSSKSRRKRQ 265
Query: 302 LDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTV 361
+T+ + + CCVR LYIDFR+DLGWKW+HEP GYYAN+C+G C ++ +++ +S V
Sbjct: 266 TETDQVCTDKSDGCCVRSLYIDFRKDLGWKWIHEPSGYYANYCTGSCSFVWTSENKYSQV 325
Query: 362 LGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKC 411
L LY NP ASA PC VPQ L PL I YYVGR KVEQLSNM+VK+CKC
Sbjct: 326 LALYKHHNPGASAQPCRVPQVLNPLPIFYYVGRQHKVEQLSNMIVKTCKC 375
>pdb|1TGJ| Human Transforming Growth Factor-Beta 3, Crystallized From Dioxane
pdb|1TGK| Human Transforming Growth Factor Beta 3, Crystallized From Peg
4000
Length = 112
Score = 250 bits (633), Expect = 2e-65
Identities = 112/112 (100%), Positives = 112/112 (100%)
Query: 301 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST 360
ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST
Sbjct: 1 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST 60
Query: 361 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
Sbjct: 61 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 112
>pir||A34941 transforming growth factor beta-4 precursor - chicken
Length = 304
Score = 248 bits (626), Expect = 1e-64
Identities = 133/273 (48%), Positives = 171/273 (61%), Gaps = 21/273 (7%)
Query: 143 RTNLFRAEFRVLRVPNPS-SKRNEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLS 201
R L RAE R+LR + S EQR+EL+Q A RY+ G+++ EWLS
Sbjct: 50 RALLHRAELRMLRQKAAADSAGTEQRLELYQ----GYGNASWRYLHGRSVRATADDEWLS 105
Query: 202 FDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGR 261
FDVTD V +WL E ++S+HCPC + D M I +G + + R
Sbjct: 106 FDVTDAVHQWLSGSELLGVFKLSVHCPCEMGPGHAD-------EMRISIEGFEQQ----R 154
Query: 262 GDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFR--NLEENCCVRP 319
GD+ + K K P+++ M +P R + R++R LDT+YCF E+NCCVRP
Sbjct: 155 GDMQSIAK-KHRRVPYVLAMALPAERANELHSA--RRRRDLDTDYCFGPGTDEKNCCVRP 211
Query: 320 LYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCV 379
LYIDFR+DL WKW+HEPKGY ANFC GPCPY+ SADT ++ VL LYN NP ASA+PCCV
Sbjct: 212 LYIDFRKDLQWKWIHEPKGYMANFCMGPCPYIWSADTQYTKVLALYNQHNPGASAAPCCV 271
Query: 380 PQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
PQ L+PL I+YYVGR +VEQLSNMVV++CKCS
Sbjct: 272 PQTLDPLPIIYYVGRNVRVEQLSNMVVRACKCS 304
>sp|P21214|TGF2_BOVIN TRANSFORMING GROWTH FACTOR BETA 2 (TGF-BETA 2) (MILK GROWTH FACTOR)
(MGF)
pir||A61439 transforming growth factor beta-2 - bovine
pdb|2TGI| Transforming Growth Factor-Beta Two (Tgf-B2)
pdb|1TFG| Transforming Growth Factor Type Beta 2 (Tgf-B2)
Length = 112
Score = 212 bits (535), Expect = 5e-54
Identities = 89/112 (79%), Positives = 103/112 (91%)
Query: 301 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST 360
ALD YCFRN+++NCC+RPLYIDF++DLGWKW+HEPKGY ANFC+G CPYL S+DT HS
Sbjct: 1 ALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHSR 60
Query: 361 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
VL LYNT+NPEASASPCCV QDLEPLTILYY+G+TPK+EQLSNM+VKSCKCS
Sbjct: 61 VLSLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMIVKSCKCS 112
>pdb|1KLA|A Chain A, Solution Structure Of Tgf-B1, Nmr, Models 1-17 Of 33
Structures
pdb|1KLA|B Chain B, Solution Structure Of Tgf-B1, Nmr, Models 1-17 Of 33
Structures
pdb|1KLC|A Chain A, Solution Structure Of Tgf-B1, Nmr, Minimized Average
Structure
pdb|1KLC|B Chain B, Solution Structure Of Tgf-B1, Nmr, Minimized Average
Structure
pdb|1KLD|A Chain A, Solution Structure Of Tgf-B1, Nmr, Models 18-33 Of 33
Structures
pdb|1KLD|B Chain B, Solution Structure Of Tgf-B1, Nmr, Models 18-33 Of 33
Structures
gb|AAA36735.1| (M38449) transforming growth factor-beta [Homo sapiens]
gb|AAB53806.1| (AF000133) transforming growth factor beta-1 [Oryctolagus
cuniculus]
Length = 112
Score = 199 bits (500), Expect = 6e-50
Identities = 86/112 (76%), Positives = 97/112 (85%)
Query: 301 ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST 360
ALDTNYCF + E+NCCVR LYIDFR+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S
Sbjct: 1 ALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSK 60
Query: 361 VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
VL LYN NP ASA+PCCVPQ LEPL I+YYVGR PKVEQLSNM+V+SCKCS
Sbjct: 61 VLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS 112
>pir||I48196 transforming growth factor beta-1 precursor - golden hamster
(fragment)
emb|CAA42838.1| (X60296) transforming growth factor-beta 1 [Mesocricetus auratus]
Length = 130
Score = 198 bits (499), Expect = 8e-50
Identities = 87/116 (75%), Positives = 98/116 (84%)
Query: 297 RKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADT 356
R +RALDTNYCF + E+NCCVR LYIDFR+DLGWKW+HEPKGY+ANFC GPCPY+ S DT
Sbjct: 15 RHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDT 74
Query: 357 THSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
+S VL LYN NP ASA PCCVPQ LEPL I+YYVGR PKVEQLSNM+V+S KCS
Sbjct: 75 QYSKVLALYNQHNPGASAGPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSYKCS 130
>gb|AAA31526.1| (L36038) transforming growth factor-beta 1 [Ovis aries]
Length = 110
Score = 196 bits (492), Expect = 5e-49
Identities = 84/110 (76%), Positives = 95/110 (86%)
Query: 303 DTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVL 362
DTNYCF + E+NCCVR LYIDFR+DLGWKW+HEPKGY+ANFC GPCPY+ S DT +S VL
Sbjct: 1 DTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVL 60
Query: 363 GLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
LYN NP ASA+PCCVPQ LEPL I+YYVGR PKVEQLSNM+V+SCKCS
Sbjct: 61 ALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS 110
>emb|CAA67685.1| (X99303) TGF [Oncorhynchus mykiss]
Length = 202
Score = 192 bits (484), Expect = 5e-48
Identities = 100/214 (46%), Positives = 125/214 (57%), Gaps = 18/214 (8%)
Query: 199 WLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDD 258
W+SFDVT T+ EWL G ++ + C C G +E K G++
Sbjct: 7 WVSFDVTQTLNEWLQGAGEEQGFQLKLPCDC------GKPMEEFR----FKISGMNKL-- 54
Query: 259 HGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVR 318
RGD L K PH++LM +P R Q RKKR T + E+CCVR
Sbjct: 55 --RGDTETLA-MKMPSKPHILLMSLPVER---HSQLSSRKKRQTTTEEICSDKSESCCVR 108
Query: 319 PLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCC 378
LYIDFR+DLGWKW+HEP GY+AN+C GPC Y+ + + +S VL LY NP ASA PCC
Sbjct: 109 KLYIDFRKDLGWKWIHEPTGYFANYCIGPCTYIWNTENKYSQVLALYKHHNPGASAHPCC 168
Query: 379 VPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS 412
VPQ LEPL I+YYVGR KVEQ+ NM+V SC+CS
Sbjct: 169 VPQVLEPLPIIYYVGRQHKVEQVPNMIVMSCRCS 202
Database: nr
Number of letters in database: 183,345,511
Number of sequences in database: 582,290
Lambda K H
0.321 0.138 0.427
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 148911983
Number of Sequences: 582290
Number of extensions: 6293193
Number of successful extensions: 12679
Number of sequences better than 10.0: 403
Number of HSP's better than 10.0 without gapping: 314
Number of HSP's successfully gapped in prelim test: 89
Number of HSP's that attempted gapping in prelim test: 11673
Number of HSP's gapped (non-prelim): 535
length of query: 412
length of database: 183,345,511
effective HSP length: 53
effective length of query: 359
effective length of database: 152,484,141
effective search space: 54741806619
effective search space used: 54741806619
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 72 (32.5 bits)
