Score E
Sequences producing significant alignments: (bits) Value
sp|P51884|LUM_HUMAN LUMICAN PRECURSOR (LUM) (KERATAN SULFAT... 653 0.0
ref|NP_002336.1| lumican [Homo sapiens] >gi|699577|gb|AAA91... 648 0.0
sp|Q05443|LUM_BOVIN LUMICAN PRECURSOR (LUM) (KERATAN SULFAT... 587 e-167
ref|NP_032550.1| lumican [Mus sp.] >gi|1708879|sp|P51885|LU... 577 e-164
sp|P51886|LUM_RAT LUMICAN PRECURSOR (LUM) (KERATAN SULFATE ... 573 e-162
sp|P51890|LUM_CHICK LUMICAN PRECURSOR (LUM) (KERATAN SULFAT... 462 e-129
gb|AAC39517.1| (AF020292) lumican [Oryctolagus cuniculus] 346 3e-94
ref|NP_067330.1| fibromodulin [Mus musculus] >gi|1706876|sp... 288 5e-77
sp|P13605|FMOD_BOVIN FIBROMODULIN PRECURSOR (FM) (COLLAGEN-... 286 2e-76
sp|P50609|FMOD_RAT FIBROMODULIN PRECURSOR (FM) >gi|602884|e... 286 3e-76
sp|P51887|FMOD_CHICK FIBROMODULIN PRECURSOR (FM) >gi|213433... 285 6e-76
sp|Q06828|FMOD_HUMAN FIBROMODULIN PRECURSOR (FM) (COLLAGEN-... 283 2e-75
ref|NP_002014.1| fibromodulin precursor [Homo sapiens] >gi|... 281 6e-75
gb|AAC48568.1| (U48360) keratan sulfate proteoglycan core p... 231 9e-60
gb|AAC69272.1| (AF036962) corneal keratan sulfate proteogly... 230 2e-59
gb|AAG23724.1|AF163569_1 (AF163569) proline arginine-rich e... 227 2e-58
ref|NP_032464.1| keratocan [Mus musculus] >gi|2570493|gb|AA... 226 3e-58
ref|NP_008966.1| keratocan; cornea plana 2 (autosomal reces... 223 2e-57
ref|NP_002716.1| proline arginine-rich end leucine-rich rep... 222 3e-57
gb|AAF72994.1|AF261888_1 (AF261888) PRELP [Mus musculus] 222 4e-57
gb|AAC15506.1| (AF022890) keratan sulfate proteoglycan [Gal... 222 4e-57
gb|AAG23723.1|AF163568_1 (AF163568) proline arginine-rich e... 219 3e-56
ref|NP_005005.1| osteomodulin [Homo sapiens] >gi|1769800|db... 216 2e-55
gb|AAD04570.1| (AF104362) osteoadherin [Rattus norvegicus] 209 3e-53
gb|AAC39259.1| (U67279) osteoadherin [Bos taurus] 208 7e-53
ref|NP_036180.1| osteomodulin; osteoadherin [Mus musculus] ... 203 2e-51
gb|AAC39516.1| (AF020291) fibromodulin [Oryctolagus cuniculus] 156 4e-37
gb|AAF19154.1| (AF159383) fibromodulin [Sus scrofa] 154 1e-36
ref|NP_031859.1| decorin [Mus musculus] >gi|129952|sp|P2865... 141 1e-32
sp|P28675|PGS2_CHICK BONE PROTEOGLYCAN II PRECURSOR (PG-S2)... 136 5e-31
ref|NP_001911.1| decorin [Homo sapiens] >gi|129951|sp|P0758... 134 2e-30
sp|Q01129|PGS2_RAT BONE PROTEOGLYCAN II PRECURSOR (PG-S2) (... 131 9e-30
emb|CAA42519.1| (X59859) decorin [Rattus norvegicus] 131 9e-30
gb|AAA52301.1| (L01131) decorin [Homo sapiens] 131 2e-29
sp|Q9XSD9|PGS2_PIG BONE PROTEOGLYCAN II PRECURSOR (PG-S2) (... 129 5e-29
sp|P21793|PGS2_BOVIN BONE PROTEOGLYCAN II PRECURSOR (PG-S2)... 129 5e-29
gb|AAF00585.1|AF125041_1 (AF125041) decorin [Ovis aries] 129 6e-29
sp|Q28888|PGS2_RABIT BONE PROTEOGLYCAN II PRECURSOR (PG-S2)... 129 6e-29
gb|AAC04315.1| (U03394) decorin [Oryctolagus cuniculus] 129 6e-29
dbj|BAA90246.1| (AB037269) biglycan [Xenopus laevis] 126 4e-28
sp|O46542|PGS2_HORSE BONE PROTEOGLYCAN II PRECURSOR (PG-S2)... 125 5e-28
sp|Q29393|PGS2_CANFA BONE PROTEOGLYCAN II PRECURSOR (PG-S2)... 125 7e-28
gb|AAD33862.1|AF140270_1 (AF140270) decorin [Sus scrofa] 123 3e-27
ref|NP_001384.1| extracellular matrix protein 2 [Homo sapie... 122 8e-27
ref|NP_001702.1| biglycan [Homo sapiens] >gi|266762|sp|P218... 120 2e-26
sp|O46390|PGS1_SHEEP BONE/CARTILAGE PROTEOGLYCAN I PRECURSO... 119 4e-26
pir||S32559 biglycan precursor - bovine 119 4e-26
sp|P21809|PGS1_BOVIN BONE/CARTILAGE PROTEOGLYCAN I PRECURSO... 118 7e-26
sp|O46403|PGS1_HORSE BONE/CARTILAGE PROTEOGLYCAN I PRECURSO... 118 7e-26
ref|NP_058783.1| small proteoglycan I (biglycan), bone (BSP... 117 2e-25
>sp|P51884|LUM_HUMAN LUMICAN PRECURSOR (LUM) (KERATAN SULFATE PROTEOGLYCAN)
gb|AAA85268.1| (U18728) lumican [Homo sapiens]
Length = 338
Score = 653 bits (1666), Expect = 0.0
Identities = 322/338 (95%), Positives = 322/338 (95%)
Query: 1 MSLSAFTLFLALIGGTSGQYYDYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKS 60
MSLSAFTLFLALIGGTSGQYYDYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKS
Sbjct: 1 MSLSAFTLFLALIGGTSGQYYDYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKS 60
Query: 61 VPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKK 120
VPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKK
Sbjct: 61 VPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKK 120
Query: 121 LHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAF 180
LHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAF
Sbjct: 121 LHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAF 180
Query: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNE 240
KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNE
Sbjct: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNE 240
Query: 241 LADSGIPGNSFNVSSLVELDLSYNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFCKILGP 300
LADSGIPGNSFNVSSLVELDLSYNKLKNIPT KFDIKSFCKILGP
Sbjct: 241 LADSGIPGNSFNVSSLVELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGP 300
Query: 301 LSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN 338
LSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN
Sbjct: 301 LSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN 338
>ref|NP_002336.1| lumican [Homo sapiens]
gb|AAA91639.1| (U21128) lumican [Homo sapiens]
Length = 338
Score = 648 bits (1653), Expect = 0.0
Identities = 320/338 (94%), Positives = 321/338 (94%)
Query: 1 MSLSAFTLFLALIGGTSGQYYDYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKS 60
MSLSAFTLFLALIGGTSGQYYDYDFP SIYGQSSPNCAPECNCPESYPSAMYCDELKLKS
Sbjct: 1 MSLSAFTLFLALIGGTSGQYYDYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKS 60
Query: 61 VPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKK 120
VPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHN+LENSKIKGRVFSKLKQLKK
Sbjct: 61 VPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKK 120
Query: 121 LHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAF 180
LHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAF
Sbjct: 121 LHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAF 180
Query: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNE 240
KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNE
Sbjct: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNE 240
Query: 241 LADSGIPGNSFNVSSLVELDLSYNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFCKILGP 300
LADSGIPGNSFNVSSLVELDLSYNKLKNIPT KFDIKSFCKILGP
Sbjct: 241 LADSGIPGNSFNVSSLVELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGP 300
Query: 301 LSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN 338
LSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN
Sbjct: 301 LSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN 338
>sp|Q05443|LUM_BOVIN LUMICAN PRECURSOR (LUM) (KERATAN SULFATE PROTEOGLYCAN) (KSPG)
(PROTEIN 37B)
pir||A46743 lumican precursor - bovine
gb|AAA30608.1| (L11063) lumican precursor protein [Bos taurus]
Length = 342
Score = 587 bits (1498), Expect = e-167
Identities = 286/342 (83%), Positives = 309/342 (89%), Gaps = 4/342 (1%)
Query: 1 MSLSAFTLFLALIGGTSGQYYDY----DFPPSIYGQSSPNCAPECNCPESYPSAMYCDEL 56
M+L F L LALIGG S Y DY DFP ++YG+SSPNCAPECNCPESYPSAMYCDEL
Sbjct: 1 MNLGVFPLLLALIGGASSTYPDYYEYYDFPQALYGRSSPNCAPECNCPESYPSAMYCDEL 60
Query: 57 KLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLK 116
KLKSVPMVPPGIKYLYLRNNQIDHID+KAFENVTDLQWLILDHN+LENSKIKG+VFSKLK
Sbjct: 61 KLKSVPMVPPGIKYLYLRNNQIDHIDDKAFENVTDLQWLILDHNLLENSKIKGKVFSKLK 120
Query: 117 QLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAV 176
QLKKLHIN+NNLTESVGPLPKSL DLQLT+NKI+KLGSF+GLVNLTFIHLQHN+LKEDAV
Sbjct: 121 QLKKLHINYNNLTESVGPLPKSLVDLQLTNNKISKLGSFDGLVNLTFIHLQHNQLKEDAV 180
Query: 177 SAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRL 236
SAA KGLKSLEYLDLSFNQ+ +LPSGLPVSLLTLYLDNNKISNIPDEYFKRF+ALQYLRL
Sbjct: 181 SAALKGLKSLEYLDLSFNQMTKLPSGLPVSLLTLYLDNNKISNIPDEYFKRFSALQYLRL 240
Query: 237 SHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFCK 296
SHNELADSG+PGNSFNVSSL+ELDLSYNKLK+IPT KFD+KSFCK
Sbjct: 241 SHNELADSGVPGNSFNVSSLLELDLSYNKLKSIPTVNENLENYYLEVNELEKFDVKSFCK 300
Query: 297 ILGPLSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN 338
ILGPLSYSKIKHLRLDGN I++TSLPPDMYECLRVANE+T+N
Sbjct: 301 ILGPLSYSKIKHLRLDGNHITQTSLPPDMYECLRVANEITVN 342
>ref|NP_032550.1| lumican [Mus sp.]
sp|P51885|LUM_MOUSE LUMICAN PRECURSOR (LUM) (KERATAN SULFATE PROTEOGLYCAN)
gb|AAB35361.1| (S79461) lumican [mice, cornea, Peptide, 338 aa] [Mus sp.]
gb|AAB87767.1| (AF013262) lumican [Mus musculus]
Length = 338
Score = 577 bits (1470), Expect = e-164
Identities = 274/338 (81%), Positives = 307/338 (90%)
Query: 1 MSLSAFTLFLALIGGTSGQYYDYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKS 60
M++ AF+L LAL+G SGQYYDYD P +YGQ SPNCAPECNCP SYP+AMYCD+LKLKS
Sbjct: 1 MNVCAFSLALALVGSVSGQYYDYDIPLFMYGQISPNCAPECNCPHSYPTAMYCDDLKLKS 60
Query: 61 VPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKK 120
VPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHN+LENSKIK +VFSKLKQLKK
Sbjct: 61 VPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKEKVFSKLKQLKK 120
Query: 121 LHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAF 180
LHIN+NNLTESVGPLPKSL+DLQLT+NKI+KLGSF+GLVNLTFI+LQHN+LKEDAVSA+
Sbjct: 121 LHINYNNLTESVGPLPKSLQDLQLTNNKISKLGSFDGLVNLTFIYLQHNQLKEDAVSASL 180
Query: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNE 240
KGLKSLEYLDLSFNQ+++LP+GLP SLLTLYLDNNKISNIPDEYFKRF LQYLRLSHNE
Sbjct: 181 KGLKSLEYLDLSFNQMSKLPAGLPTSLLTLYLDNNKISNIPDEYFKRFTGLQYLRLSHNE 240
Query: 241 LADSGIPGNSFNVSSLVELDLSYNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFCKILGP 300
LADSG+PGNSFN+SSL+ELDLSYNKLK+IPT KFD+K+FCKILGP
Sbjct: 241 LADSGVPGNSFNISSLLELDLSYNKLKSIPTVNENLENYYLEVNELEKFDVKTFCKILGP 300
Query: 301 LSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN 338
LSYSKIKHLRLDGN ++++SLPPDMYECLRVANE+T+N
Sbjct: 301 LSYSKIKHLRLDGNPLTQSSLPPDMYECLRVANEITVN 338
>sp|P51886|LUM_RAT LUMICAN PRECURSOR (LUM) (KERATAN SULFATE PROTEOGLYCAN)
pir||S52284 lumicon, secretory intersticial proteoglycan precursor - rat
emb|CAA58858.1| (X84039) lumican, secretory intersticial proteoglycan [Rattus
norvegicus]
Length = 338
Score = 573 bits (1460), Expect = e-162
Identities = 271/338 (80%), Positives = 305/338 (90%)
Query: 1 MSLSAFTLFLALIGGTSGQYYDYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKS 60
M++ FTL LAL+G SGQYYDYD P +YG+ SPNCAPECNCP SYP+AMYCD+LKLKS
Sbjct: 1 MNVCTFTLVLALVGSVSGQYYDYDAPLFMYGELSPNCAPECNCPHSYPTAMYCDDLKLKS 60
Query: 61 VPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKK 120
VPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHN+LENSKIKG+VFSKLKQLKK
Sbjct: 61 VPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGKVFSKLKQLKK 120
Query: 121 LHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAF 180
LHIN+NNLTESVGPLPKSL+DLQL +NKI+KLGSF+GLVNLTFI+LQHN+LKE+AVSA+
Sbjct: 121 LHINYNNLTESVGPLPKSLQDLQLANNKISKLGSFDGLVNLTFIYLQHNQLKEEAVSASL 180
Query: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNE 240
KGLKSLEYLDLSFNQ+++LP+GLP SLLTLYLDNNKI+NIPDEYF RF LQYLRLSHNE
Sbjct: 181 KGLKSLEYLDLSFNQMSKLPAGLPTSLLTLYLDNNKITNIPDEYFNRFTGLQYLRLSHNE 240
Query: 241 LADSGIPGNSFNVSSLVELDLSYNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFCKILGP 300
LADSG+PGNSFN+SSL+ELDLSYNKLK+IPT KFD+KSFCKILGP
Sbjct: 241 LADSGVPGNSFNISSLLELDLSYNKLKSIPTVNENLENYYLEVNKLEKFDVKSFCKILGP 300
Query: 301 LSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN 338
LSYSKIKHLRLDGN ++++SLPPDMYECLRVANE+T+N
Sbjct: 301 LSYSKIKHLRLDGNPLTQSSLPPDMYECLRVANEITVN 338
>sp|P51890|LUM_CHICK LUMICAN PRECURSOR (LUM) (KERATAN SULFATE PROTEOGLYCAN)
pir||A41748 lumican precursor - chicken
Length = 343
Score = 462 bits (1175), Expect = e-129
Identities = 226/344 (65%), Positives = 272/344 (78%), Gaps = 9/344 (2%)
Query: 1 MSLSAFTLFLALIGGTSGQYY-----DYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDE 55
M+L++ +FL LI G QY DY + P +G S+ CAPECNCP SYP+AMYCD
Sbjct: 1 MTLNSLPIFLVLISGIFCQYDYGPADDYGYDP--FGPSTAVCAPECNCPLSYPTAMYCDN 58
Query: 56 LKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKL 115
LKLK++P+VP GIKYLYLRNN I+ I+E F+NVTDLQWLILDHN LENSKIKGRVFSKL
Sbjct: 59 LKLKTIPIVPSGIKYLYLRNNMIEAIEENTFDNVTDLQWLILDHNHLENSKIKGRVFSKL 118
Query: 116 KQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKE 173
K LKKLHIN+NNLTE+VGPLPK+L+DLQL+HNKITK+ G+ EGLVNLT IHLQ+N+LK
Sbjct: 119 KNLKKLHINYNNLTEAVGPLPKTLDDLQLSHNKITKVNPGALEGLVNLTVIHLQNNQLKT 178
Query: 174 DAVSAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQY 233
D++S AFKGL SL YLDLSFNQ+ +LP+GLP SLL LY DNN+ISNIPDEYF+ F LQY
Sbjct: 179 DSISGAFKGLNSLLYLDLSFNQLTKLPTGLPHSLLMLYFDNNQISNIPDEYFQGFKTLQY 238
Query: 234 LRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTXXXXXXXXXXXXXXXXKFDIKS 293
LRLSHN+L DSGIPGN FN++SLVELDLS+N+LK+IPT KF + S
Sbjct: 239 LRLSHNKLTDSGIPGNVFNITSLVELDLSFNQLKSIPTVSENLENFYLQVNKINKFPLSS 298
Query: 294 FCKILGPLSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTL 337
FCK++GPL+YSKI HLRLDGN ++ LP +MY CLRVA +++L
Sbjct: 299 FCKVVGPLTYSKITHLRLDGNNLTRADLPQEMYNCLRVAADISL 342
>gb|AAC39517.1| (AF020292) lumican [Oryctolagus cuniculus]
Length = 192
Score = 346 bits (877), Expect = 3e-94
Identities = 167/180 (92%), Positives = 178/180 (98%)
Query: 92 LQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITK 151
LQWLILDHN+LENSKIKG+VFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITK
Sbjct: 1 LQWLILDHNLLENSKIKGKVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITK 60
Query: 152 LGSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLY 211
LGSF+GL+NLTF+HLQHN+LKEDAVSAAFKGLKSLEYLDLSFNQ+++LPSGLP SLLTLY
Sbjct: 61 LGSFDGLLNLTFVHLQHNQLKEDAVSAAFKGLKSLEYLDLSFNQMSKLPSGLPASLLTLY 120
Query: 212 LDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPT 271
LDNNKIS+IPDEYFKRFN LQYLRLSHNELADSGIPGNSFN+SSLVELDLSYNKLKNIPT
Sbjct: 121 LDNNKISDIPDEYFKRFNGLQYLRLSHNELADSGIPGNSFNISSLVELDLSYNKLKNIPT 180
Score = 45.3 bits (105), Expect = 0.001
Identities = 27/81 (33%), Positives = 48/81 (58%), Gaps = 2/81 (2%)
Query: 64 VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHI 123
+P + LYL NN+I I ++ F+ LQ+L L HN L +S I G F+ + L +L +
Sbjct: 112 LPASLLTLYLDNNKISDIPDEYFKRFNGLQYLRLSHNELADSGIPGNSFN-ISSLVELDL 170
Query: 124 NHNNLTESVGPLPKSLEDLQL 144
++N L +++ + ++LE+ L
Sbjct: 171 SYNKL-KNIPTVNENLENYYL 190
>ref|NP_067330.1| fibromodulin [Mus musculus]
sp|P50608|FMOD_MOUSE FIBROMODULIN PRECURSOR (FM)
emb|CAA64454.1| (X94998) fibromodulin [Mus musculus]
Length = 376
Score = 288 bits (730), Expect = 5e-77
Identities = 142/326 (43%), Positives = 209/326 (63%), Gaps = 7/326 (2%)
Query: 14 GGTSGQYYDYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYL 73
G G Y Y PP +C EC+CP ++P+AMYCD LK +P VP +KY+Y
Sbjct: 56 GVEEGPAYAYGAPPP---PEPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYF 112
Query: 74 RNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVG 133
+NNQI I E F+N T L W+ L N + + K+ +VFSKL+ L++L+++HNNLT G
Sbjct: 113 QNNQISAIQEGVFDNATGLLWVALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPG 172
Query: 134 PLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDL 191
PLP+SL +L L HN+I+++ + EGL NLT ++L HN ++E V ++ +GL+SL LDL
Sbjct: 173 PLPRSLRELHLDHNQISRVPNNALEGLENLTALYLHHNEIQE--VGSSMRGLRSLILLDL 230
Query: 192 SFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSF 251
S+N + R+P GLP +L LYL++N + +PD YF+ L Y+RLSHN L ++G+ N+F
Sbjct: 231 SYNHLRRVPDGLPSALEQLYLEHNNVYTVPDSYFRGSPKLLYVRLSHNSLTNNGLATNTF 290
Query: 252 NVSSLVELDLSYNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFCKILGPLSYSKIKHLRL 311
N SSL+ELDLSYN+L+ IP +F I SFC ++ +++SK++ LRL
Sbjct: 291 NSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVMNFSKLQVLRL 350
Query: 312 DGNRISETSLPPDMYECLRVANEVTL 337
DGN I +++P D CLR+AN + +
Sbjct: 351 DGNEIKRSAMPVDAPLCLRLANLIEI 376
>sp|P13605|FMOD_BOVIN FIBROMODULIN PRECURSOR (FM) (COLLAGEN-BINDING 59 KD PROTEIN)
pir||S05390 fibromodulin precursor - bovine
emb|CAA34503.1| (X16485) fibromodulin [Bos taurus]
Length = 375
Score = 286 bits (725), Expect = 2e-76
Identities = 141/326 (43%), Positives = 210/326 (64%), Gaps = 9/326 (2%)
Query: 15 GTSGQYYDYDFPPSIYGQSSP-NCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYL 73
G G Y Y PP Q P +C EC+CP ++P+AMYCD LK +P VP +KY+Y
Sbjct: 56 GEEGPAYAYGSPP----QPEPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYF 111
Query: 74 RNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVG 133
+NNQI I E F+N T L W+ L N + + K+ +VFSKL+ L++L+++HNNLT
Sbjct: 112 QNNQISSIQEGVFDNATGLLWIALHGNQITSDKVGKKVFSKLRHLERLYLDHNNLTRIPS 171
Query: 134 PLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDL 191
PLP+SL +L L HN+I+++ + EGL NLT ++L HN ++E V ++ KGL+SL LDL
Sbjct: 172 PLPRSLRELHLDHNQISRVPNNALEGLENLTALYLHHNEIQE--VGSSMKGLRSLILLDL 229
Query: 192 SFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSF 251
S+N + ++P GLP +L LYL++N + ++PD YF+ L Y+RLSHN L ++G+ N+F
Sbjct: 230 SYNHLRKVPDGLPSALEQLYLEHNNVFSVPDSYFRGSPKLLYVRLSHNSLTNNGLASNTF 289
Query: 252 NVSSLVELDLSYNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFCKILGPLSYSKIKHLRL 311
N SSL+ELDLSYN+L+ IP +F I SFC ++ +++SK++ RL
Sbjct: 290 NSSSLLELDLSYNQLQKIPPVSTNLENLYLQGNRINEFSISSFCTVVDVMNFSKLQVQRL 349
Query: 312 DGNRISETSLPPDMYECLRVANEVTL 337
DGN I +++P D CLR+A+ + +
Sbjct: 350 DGNEIKRSAMPADAPLCLRLASLIEI 375
>sp|P50609|FMOD_RAT FIBROMODULIN PRECURSOR (FM)
emb|CAA57648.1| (X82152) fibromodulin [Rattus norvegicus]
Length = 376
Score = 286 bits (723), Expect = 3e-76
Identities = 141/322 (43%), Positives = 208/322 (63%), Gaps = 7/322 (2%)
Query: 18 GQYYDYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQ 77
G Y Y PP +C EC+CP ++P+AMYCD LK +P VP +KY+Y +NNQ
Sbjct: 60 GPAYAYGAPPP---PEPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQ 116
Query: 78 IDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPK 137
I I E F+N T L W+ L N + + KI +VFSKL+ L++L+++HNNLT GPLP+
Sbjct: 117 IAAIQEGVFDNATGLLWIALHGNQITSDKIGRKVFSKLRHLERLYLDHNNLTRMPGPLPR 176
Query: 138 SLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQ 195
SL +L L HN+I+++ + EGL NLT ++L HN ++E V ++ +GL+SL LDLS+N
Sbjct: 177 SLRELHLDHNQISRVPNNALEGLENLTALYLHHNEIQE--VGSSMRGLRSLILLDLSYNH 234
Query: 196 IARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSS 255
+ R+P GLP +L LYL++N + +PD YF+ L Y+RLSHN L ++G+ N+FN SS
Sbjct: 235 LRRVPDGLPSALEQLYLEHNNVYTVPDSYFRGSPKLLYVRLSHNSLTNNGLATNTFNSSS 294
Query: 256 LVELDLSYNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFCKILGPLSYSKIKHLRLDGNR 315
L+ELDLSYN+L+ IP +F I SFC ++ +++SK++ LRLDGN
Sbjct: 295 LLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVMNFSKLQVLRLDGNE 354
Query: 316 ISETSLPPDMYECLRVANEVTL 337
I +++P D CLR+A+ + +
Sbjct: 355 IKRSAMPVDAPLCLRLASLIEI 376
>sp|P51887|FMOD_CHICK FIBROMODULIN PRECURSOR (FM)
pir||S71876 fibromodulin - chicken
gb|AAC60016.1| (U34977) fibromodulin [Gallus gallus]
Length = 380
Score = 285 bits (721), Expect = 6e-76
Identities = 142/313 (45%), Positives = 206/313 (65%), Gaps = 4/313 (1%)
Query: 27 PSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAF 86
P SS C EC+CP ++ SAMYCD L+ +P VP +KY+Y +NNQI I E AF
Sbjct: 70 PEAQQASSWQCPQECDCPPNFSSAMYCDTRNLRYLPFVPTRMKYVYFQNNQITAIQEGAF 129
Query: 87 ENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTH 146
+N T+L+WL L +N + + K+ RVF+KLK L++L++N+NNLT+ PLP+SL +L L++
Sbjct: 130 DNATELEWLALHNNQISSEKMGKRVFAKLKNLERLYMNNNNLTKMPSPLPRSLRELHLSY 189
Query: 147 NKITKLGS--FEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLPSGLP 204
N+I+K+ S EGL NLT ++L HN + E + A+ KGLKSL DLS+N + ++P GLP
Sbjct: 190 NQISKVPSNALEGLENLTALYLSHNYIFE--MGASLKGLKSLILADLSYNHLRKVPDGLP 247
Query: 205 VSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYN 264
++L LYL+ N I+ IPD+YFK L Y+R+SHN L + G+ N+FN SS++ELDLSYN
Sbjct: 248 MALEQLYLEYNYINAIPDDYFKVSPKLLYVRMSHNSLTNQGLSTNTFNSSSILELDLSYN 307
Query: 265 KLKNIPTXXXXXXXXXXXXXXXXKFDIKSFCKILGPLSYSKIKHLRLDGNRISETSLPPD 324
+L+ IP +F I SFC ++ ++YS+++ LRLDGN I ++PPD
Sbjct: 308 RLQKIPRVSTNLENLYLQGNQINEFSISSFCTVVDVMNYSRLQVLRLDGNEIKRNAMPPD 367
Query: 325 MYECLRVANEVTL 337
CLR A + +
Sbjct: 368 APLCLRRATVIEI 380
>sp|Q06828|FMOD_HUMAN FIBROMODULIN PRECURSOR (FM) (COLLAGEN-BINDING 59 KD PROTEIN)
emb|CAA51418.1| (X72913) fibromodulin [Homo sapiens]
Length = 376
Score = 283 bits (717), Expect = 2e-75
Identities = 135/318 (42%), Positives = 209/318 (65%), Gaps = 8/318 (2%)
Query: 26 PPSIYGQSSP----NCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHI 81
P YG SP +C EC+CP ++P+AMYCD LK +P VP +KY+Y +NNQI I
Sbjct: 61 PAYTYGSPSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSI 120
Query: 82 DEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLED 141
E F+N T L W+ L N + + K+ +VFSKL+ L++L+++HNNLT GPLP+SL +
Sbjct: 121 QEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRE 180
Query: 142 LQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARL 199
L L HN+I+++ + EGL NLT ++LQHN ++E V ++ +GL+SL LDLS+N + ++
Sbjct: 181 LHLDHNQISRVPNNALEGLENLTALYLQHNEIQE--VGSSMRGLRSLYLLDLSYNHLRKV 238
Query: 200 PSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVEL 259
P GLP +L LY+++N + +PD YF+ L Y+RLSHN L ++G+ N+FN SSL+EL
Sbjct: 239 PDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLEL 298
Query: 260 DLSYNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFCKILGPLSYSKIKHLRLDGNRISET 319
DLSYN+L+ IP +F I SFC ++ +++S+++ +RLDGN + +
Sbjct: 299 DLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSQLQVVRLDGNEMKRS 358
Query: 320 SLPPDMYECLRVANEVTL 337
++P + CLR+A+ + +
Sbjct: 359 AMPAEAPLCLRLASLIEI 376
>ref|NP_002014.1| fibromodulin precursor [Homo sapiens]
pir||S55275 fibromodulin precursor - human
emb|CAA53233.1| (X75546) fibromodulin [Homo sapiens]
Length = 376
Score = 281 bits (712), Expect = 6e-75
Identities = 136/318 (42%), Positives = 208/318 (64%), Gaps = 8/318 (2%)
Query: 26 PPSIYGQSSP----NCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHI 81
P YG SP +C EC+CP ++ +AMYCD LK +P VP +KY+Y +NNQI I
Sbjct: 61 PAYTYGSPSPPDPRDCPQECDCPPNFLTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSI 120
Query: 82 DEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLED 141
E F+N T L W+ L N + + K+ +VFSKL+ L++L+++HNNLT GPLP+SL +
Sbjct: 121 QEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRE 180
Query: 142 LQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARL 199
L L HN+I+++ + EGL NLT ++LQH+ ++E V ++ +GL+SL LDLS+N + ++
Sbjct: 181 LHLDHNQISRVPNNALEGLENLTALYLQHDEIQE--VGSSMRGLRSLILLDLSYNHLRKV 238
Query: 200 PSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVEL 259
P GLP +L LY+++N + +PD YF+ L Y+RLSHN L ++G+ N+FN SSL+EL
Sbjct: 239 PDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLEL 298
Query: 260 DLSYNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFCKILGPLSYSKIKHLRLDGNRISET 319
DLSYN+L+ IP +F I SFC ++ +++SK++ +RLDGN I +
Sbjct: 299 DLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVVRLDGNEIKRS 358
Query: 320 SLPPDMYECLRVANEVTL 337
++P D CLR+A+ + +
Sbjct: 359 AMPADAPLCLRLASLIEI 376
>gb|AAC48568.1| (U48360) keratan sulfate proteoglycan core protein 37A [Bos taurus]
prf||2211353A keratocan [Bos taurus]
Length = 352
Score = 231 bits (583), Expect = 9e-60
Identities = 121/313 (38%), Positives = 183/313 (57%), Gaps = 12/313 (3%)
Query: 36 NCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWL 95
+C EC CP S+P+A+YC+ LK +P +P I YLYL NN I+ I EK FEN T L+W+
Sbjct: 41 DCPRECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLENNLIETIPEKPFENATQLRWI 100
Query: 96 ILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL--G 153
L+ N + N I+ S+LK+L L + N L E PLP+SLE LQL NK++++ G
Sbjct: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
Query: 154 SFEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYL 212
+F L NLT + LQHN+L ++A FKGLK+L L+++ N + +P LP + + ++L
Sbjct: 161 TFSNLENLTLLDLQHNKLLDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQVFL 220
Query: 213 DNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTX 272
DNN I IP+ YF + +LRL+HN+L+D+G+P + FNVSS+++L LS+N+L +P
Sbjct: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDAGLPSSGFNVSSILDLQLSHNQLTKVPKI 280
Query: 273 XXXXXXXXXXXXXXXKFDIKSFC-------KILGPLSYS-KIKHLRLDGNRISETSLPPD 324
++ C + SY +++LRLDGN I + +P D
Sbjct: 281 SAHLQHLHLDHNKIRNVNVSVICPSTPTTLPVEDSFSYGPHLRYLRLDGNEI-KPPIPMD 339
Query: 325 MYECLRVANEVTL 337
+ C R+ V +
Sbjct: 340 LMTCFRLLQAVII 352
>gb|AAC69272.1| (AF036962) corneal keratan sulfate proteoglycan core protein 37A
[Bos taurus]
Length = 352
Score = 230 bits (580), Expect = 2e-59
Identities = 120/313 (38%), Positives = 183/313 (58%), Gaps = 12/313 (3%)
Query: 36 NCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWL 95
+C EC CP S+P+A+YC+ LK +P +P I YLYL NN I+ I EK FEN T L+W+
Sbjct: 41 DCPRECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLENNLIETIPEKPFENATQLRWI 100
Query: 96 ILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL--G 153
L+ N + N I+ S+LK+L L + N L E PLP+SLE LQL NK++++ G
Sbjct: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
Query: 154 SFEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYL 212
+F L NLT + LQHN+L ++A F+GLK+L L+++ N + +P LP + + ++L
Sbjct: 161 TFSNLENLTLLDLQHNKLLDNAFQRDTFRGLKNLMQLNMAKNALRNMPPRLPANTMQVFL 220
Query: 213 DNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTX 272
DNN I IP+ YF + +LRL+HN+L+D+G+P + FNVSS+++L LS+N+L +P
Sbjct: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDAGLPSSGFNVSSILDLQLSHNQLTKVPKI 280
Query: 273 XXXXXXXXXXXXXXXKFDIKSFC-------KILGPLSYS-KIKHLRLDGNRISETSLPPD 324
++ C + SY +++LRLDGN I + +P D
Sbjct: 281 SAHLQHLHLDHNKIRNVNVSVICPSTPTTLPVEDSFSYGPHLRYLRLDGNEI-KPPIPMD 339
Query: 325 MYECLRVANEVTL 337
+ C R+ V +
Sbjct: 340 LMTCFRLLQAVII 352
>gb|AAG23724.1|AF163569_1 (AF163569) proline arginine-rich end leucine-rich repeat protein
[Rattus norvegicus]
Length = 377
Score = 227 bits (572), Expect = 2e-58
Identities = 124/324 (38%), Positives = 191/324 (58%), Gaps = 19/324 (5%)
Query: 26 PPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKA 85
PPS++ P+C EC CP +PSA+YCD L+ VP++PP I YLYL+NN I + ++
Sbjct: 61 PPSVF----PDCPRECYCPPDFPSALYCDSRNLRKVPIIPPRIHYLYLQNNFITELPVES 116
Query: 86 FENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLT 145
F+N T L+W+ LD+N + K+ RV KL L L+++ N L E LP++LE L+L+
Sbjct: 117 FKNATGLRWINLDNNRIR--KVDQRVLEKLPGLAFLYMDKNQLEEVPSALPRNLEQLRLS 174
Query: 146 HNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSG 202
N I+++ G F L NL + LQHNRL + A F+GLK+L L+L+ N + R+P
Sbjct: 175 QNLISRIPPGVFSKLENLLLLDLQHNRLSDGVFKADTFQGLKNLMQLNLAHNILRRMPPK 234
Query: 203 LPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLS 262
+P ++ LYLD+NKI IP YFK F L ++R+++N+L+D G+P NSFN+S+L+ L LS
Sbjct: 235 VPPAIHQLYLDSNKIETIPSGYFKDFPNLAFIRMNYNKLSDRGLPKNSFNISNLLVLHLS 294
Query: 263 YNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFC--KILGPLSYSK-------IKHLRLDG 313
+NK+ N+P K + C ++ +S +++LRLDG
Sbjct: 295 HNKISNVPAISNKLEHLYLNNNSIEKINGTQICPSNLVAFHDFSSDLENVPHLRYLRLDG 354
Query: 314 NRISETSLPPDMYECLRVANEVTL 337
N + + +P D+ C R+ V +
Sbjct: 355 NFL-KPPIPLDLMMCFRLLQSVVI 377
>ref|NP_032464.1| keratocan [Mus musculus]
gb|AAC15505.1| (AF022256) corneal proteoglycan, keratocan [Mus musculus]
gb|AAC61257.1| (AF057301) keratocan [Mus musculus]
Length = 351
Score = 226 bits (570), Expect = 3e-58
Identities = 121/308 (39%), Positives = 178/308 (57%), Gaps = 18/308 (5%)
Query: 37 CAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLI 96
C EC CP S+P+A+YC+ L +P +P I YLYL NN I+ I EK FEN T L+W+
Sbjct: 43 CPRECFCPPSFPTALYCENRGLTEIPPIPSRIWYLYLENNLIESIPEKPFENATQLRWIN 102
Query: 97 LDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL--GS 154
L+ N + N I+ S+LK+L L + N L E PLP+SLE LQL NK++++ G+
Sbjct: 103 LNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGT 162
Query: 155 FEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLD 213
F L NLT + LQHN+L ++A FKGLK+L L+++ N + +P LP + + L+LD
Sbjct: 163 FSNLENLTLLDLQHNKLLDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLD 222
Query: 214 NNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTXX 273
NN I IP+ YF + +LRL+HN+L+D+G+P F+VSS+++L LSYN+L N P
Sbjct: 223 NNSIEGIPENYFNVIPKVAFLRLNHNKLSDAGLPSRGFDVSSILDLQLSYNQLTNFPRIN 282
Query: 274 XXXXXXXXXXXXXXKFDIKSFCK----------ILGPLSYSKIKHLRLDGNRISETSLPP 323
++ C I GP ++ +LRLDGN I + +P
Sbjct: 283 ANLQHLHLDHNKIKNVNMSVICPTTLRAEQDAFIHGP----QLSYLRLDGNEI-KPPIPI 337
Query: 324 DMYECLRV 331
D+ C ++
Sbjct: 338 DLVACFKL 345
>ref|NP_008966.1| keratocan; cornea plana 2 (autosomal recessive) [Homo sapiens]
gb|AAC16390.1| (AF063301) keratan sulfate proteoglycan [Homo sapiens]
gb|AAC17741.1| (AF065988) keratocan; kera; corneal keratan sulfate proteoglycan
[Homo sapiens]
gb|AAF69126.1| (AF205403) keratocan [Homo sapiens]
Length = 352
Score = 223 bits (563), Expect = 2e-57
Identities = 120/312 (38%), Positives = 181/312 (57%), Gaps = 12/312 (3%)
Query: 37 CAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLI 96
C EC CP S+P+A+YC+ LK +P +P I YLYL+NN I+ I EK FEN T L+W+
Sbjct: 42 CPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWIN 101
Query: 97 LDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL--GS 154
L+ N + N I+ S+LK+L L + N L E PLP+SLE LQL NK++++ G+
Sbjct: 102 LNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGT 161
Query: 155 FEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLD 213
F L NLT + LQ+N+L ++A FKGLK+L L+++ N + +P LP + + L+LD
Sbjct: 162 FSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLD 221
Query: 214 NNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTXX 273
NN I IP+ YF + +LRL+HN+L+D G+P F+VSS+++L LS+N+L +P
Sbjct: 222 NNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRIS 281
Query: 274 XXXXXXXXXXXXXXKFDIKSFCKILGPL-----SYS---KIKHLRLDGNRISETSLPPDM 325
++ C L S+S +++LRLDGN I + +P +
Sbjct: 282 AHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEI-KPPIPMAL 340
Query: 326 YECLRVANEVTL 337
C R+ V +
Sbjct: 341 MTCFRLLQAVII 352
>ref|NP_002716.1| proline arginine-rich end leucine-rich repeat protein [Homo
sapiens]
sp|P51888|PARG_HUMAN PROLARGIN PRECURSOR (PROLINE-ARGININE-RICH END LEUCINE-RICH REPEAT
PROTEIN)
pir||I39068 proline- arginine-rich end leucine-rich repeat protein PRELP
precursor - human
gb|AAC50230.1| (U29089) proline- arginine-rich end leucine-rich repeat protein
[Homo sapiens]
gb|AAC18782.1| (U41344) prolargin [Homo sapiens]
Length = 382
Score = 222 bits (561), Expect = 3e-57
Identities = 124/324 (38%), Positives = 188/324 (57%), Gaps = 19/324 (5%)
Query: 26 PPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKA 85
PPSI+ P+C EC CP +PSA+YCD L+ VP++PP I YLYL+NN I + ++
Sbjct: 66 PPSIF----PDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVES 121
Query: 86 FENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLT 145
F+N T L+W+ LD+N + KI RV KL L L++ N L E LP++LE L+L+
Sbjct: 122 FQNATGLRWINLDNNRIR--KIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLS 179
Query: 146 HNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSG 202
N I+++ G F L NL + LQHNRL + F GLK+L L+L+ N + ++P
Sbjct: 180 QNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPR 239
Query: 203 LPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLS 262
+P ++ LYLD+NKI IP+ YFK F L ++RL++N+L D G+P NSFN+S+L+ L LS
Sbjct: 240 VPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLS 299
Query: 263 YNKLKNIPTXXXXXXXXXXXXXXXXKF--------DIKSFCKILGPL-SYSKIKHLRLDG 313
+N++ ++P K D+ +F L + +++LRLDG
Sbjct: 300 HNRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDG 359
Query: 314 NRISETSLPPDMYECLRVANEVTL 337
N + + +P D+ C R+ V +
Sbjct: 360 NYL-KPPIPLDLMMCFRLLQSVVI 382
>gb|AAF72994.1|AF261888_1 (AF261888) PRELP [Mus musculus]
Length = 378
Score = 222 bits (560), Expect = 4e-57
Identities = 122/324 (37%), Positives = 191/324 (58%), Gaps = 19/324 (5%)
Query: 26 PPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKA 85
PPS++ P+C EC CP +PSA+YCD L+ VP++PP I YLYL+NN I + ++
Sbjct: 62 PPSVF----PDCPRECYCPPDFPSALYCDSRNLRRVPVIPPRIHYLYLQNNFITELPLES 117
Query: 86 FENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLT 145
F+N T L+W+ LD+N + K+ RV KL L L++ N L E LP++LE L+L+
Sbjct: 118 FQNATGLRWVNLDNNRIR--KVDQRVLGKLPSLAFLYMEKNQLEEVPSALPRNLEQLRLS 175
Query: 146 HNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSG 202
N I+++ G F L NL + LQHNRL + A F+GLK+L L+L+ N + ++P
Sbjct: 176 QNLISRIPPGVFSKLENLLLLDLQHNRLSDGVFKADTFQGLKNLMQLNLAHNILRKMPPK 235
Query: 203 LPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLS 262
+P ++ LYLD+NKI IP+ YFK F L ++R+++N+L+D G+P NSFN+S+L+ L LS
Sbjct: 236 VPQAIHQLYLDSNKIETIPNGYFKDFPNLAFIRMNYNKLSDRGLPKNSFNISNLLVLHLS 295
Query: 263 YNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFC--KILGPLSYSK-------IKHLRLDG 313
+NK+ N+P K + C ++ +S +++LRLDG
Sbjct: 296 HNKISNVPAISNKLEHLYLNNNSIEKINGTQICPNNLVAFHDFSSDLENVPHLRYLRLDG 355
Query: 314 NRISETSLPPDMYECLRVANEVTL 337
N + + +P D+ +R+ V +
Sbjct: 356 NFL-KPPIPLDLMMLVRLLQSVVI 378
>gb|AAC15506.1| (AF022890) keratan sulfate proteoglycan [Gallus gallus]
Length = 353
Score = 222 bits (560), Expect = 4e-57
Identities = 124/333 (37%), Positives = 186/333 (55%), Gaps = 13/333 (3%)
Query: 16 TSGQYYDYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRN 75
T Q Y+ + P + + C EC CP S+P+A+YCD LK +P +P I YLYL+N
Sbjct: 23 TVRQVYN-ELDPEHWSHYTFECPQECFCPPSFPNALYCDNKGLKEIPAIPARIWYLYLQN 81
Query: 76 NQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPL 135
N I+ I EK F N T L+W+ L+ N + N+ I+ V SKLK+L L + N L E PL
Sbjct: 82 NLIETISEKPFVNATHLRWINLNKNKITNNGIESGVLSKLKRLLYLFLEDNELEEVPAPL 141
Query: 136 PKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLS 192
P LE L+L NKI+++ G F L NLT + L N L + A+ S F+GL SL L+++
Sbjct: 142 PVGLEQLRLARNKISRIPEGVFSNLENLTMLDLHQNNLLDSALQSDTFQGLNSLMQLNIA 201
Query: 193 FNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFN 252
N + ++P +P + L L+LDNN I IP+ YF + +LRL++N+L+D GIP N FN
Sbjct: 202 KNSLKKMPLSIPANTLQLFLDNNSIEVIPENYFSAIPKVTFLRLNYNKLSDDGIPPNGFN 261
Query: 253 VSSLVELDLSYNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFCKILGPL--------SYS 304
VSS+++L LS+N+L IP + C + + +
Sbjct: 262 VSSILDLQLSHNQLTKIPPINAHLEHLHLDHNRIKSVNGTQICPVSIAVAEDYGLYGNIP 321
Query: 305 KIKHLRLDGNRISETSLPPDMYECLRVANEVTL 337
++++LRLDGN I + +P D+ C ++ V +
Sbjct: 322 RLRYLRLDGNEI-QPPIPLDIMICFQLLQAVVI 353
>gb|AAG23723.1|AF163568_1 (AF163568) proline arginine-rich end leucine-rich repeat protein
[Bos taurus]
Length = 381
Score = 219 bits (553), Expect = 3e-56
Identities = 119/324 (36%), Positives = 189/324 (57%), Gaps = 19/324 (5%)
Query: 26 PPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKA 85
PPS++ P+C EC CP +PSA+YCD L+ VP++P I YLYL+NN I + ++
Sbjct: 65 PPSVF----PDCPRECYCPPDFPSALYCDSRNLRKVPVIPSRIHYLYLQNNFITELPVES 120
Query: 86 FENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLT 145
F+N T L+W+ LD+N + K+ RV KL L L++ N L E LP++LE L+L+
Sbjct: 121 FKNATGLRWINLDNNRIR--KVDQRVLEKLPSLVFLYLEKNQLEEVPAALPRNLEQLRLS 178
Query: 146 HNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSG 202
N+I+++ G F L NL + LQHN+L + F+GLK+L L+L+ N + ++P
Sbjct: 179 QNQISRIPPGVFSKLENLLLLDLQHNKLSDGVFKPDTFQGLKNLMQLNLAHNTLRKMPPK 238
Query: 203 LPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLS 262
+P ++ LYLD+N+I IP YFK F L ++RL++N+L+D G+P NSFN+S+L+ L LS
Sbjct: 239 VPSAIHQLYLDSNRIEAIPSGYFKGFPNLAFIRLNYNQLSDRGLPKNSFNISNLLVLHLS 298
Query: 263 YNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFC--KILGPLSYSK-------IKHLRLDG 313
+N++ ++P K + C I+ +S +++LRLDG
Sbjct: 299 HNRISSVPAISSRLEHLYLNNNSIEKINGTQICPNNIVAFHDFSSDLEHVPHLRYLRLDG 358
Query: 314 NRISETSLPPDMYECLRVANEVTL 337
N + + +P D+ C R+ V +
Sbjct: 359 NYL-KPPIPLDLMMCFRLLQSVVI 381
>ref|NP_005005.1| osteomodulin [Homo sapiens]
dbj|BAA19055.1| (AB000114) osteomodulin [Homo sapiens]
dbj|BAA23982.1| (AB009589) Osteomodulin [Homo sapiens]
Length = 421
Score = 216 bits (545), Expect = 2e-55
Identities = 120/303 (39%), Positives = 179/303 (58%), Gaps = 8/303 (2%)
Query: 19 QYYDYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQI 78
Q DY P + Q + C EC CP ++PS+MYCD KLK++P +P I+ LYL+ N+I
Sbjct: 47 QNVDYGVP---FHQYTLGCVSECFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEI 103
Query: 79 DHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKS 138
+ + +F N T L+ + L HN +++ KI VF+KL L +LH+ HNNL E PLPKS
Sbjct: 104 EAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKS 163
Query: 139 LEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQ 195
LE L L +N+I+KL + +GLVNLT + L +N L + + F ++ L L+L N+
Sbjct: 164 LERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNR 223
Query: 196 IARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSS 255
+ +P GLP SL+ L L+NN IS+IP++YF + L LR+SHN+L D IP N FN+ +
Sbjct: 224 LESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQD--IPYNIFNLPN 281
Query: 256 LVELDLSYNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFCKILGPLSYSKIKHLRLDGNR 315
+VEL + +NKLK K ++ C + PL Y + ++R+D N+
Sbjct: 282 IVELSVGHNKLKQAFYIPRNLEHLYLQNNEIEKMNLTVMCPSIDPLHYHHLTYIRVDQNK 341
Query: 316 ISE 318
+ E
Sbjct: 342 LKE 344
Score = 46.5 bits (108), Expect = 4e-04
Identities = 44/187 (23%), Positives = 85/187 (44%), Gaps = 41/187 (21%)
Query: 57 KLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKL 115
+L+S+P +P + YL L NN I I EK F+ + L L + HN L++ I +F+ L
Sbjct: 223 RLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQD--IPYNIFN-L 279
Query: 116 KQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDA 175
+ +L + HN L ++ +P++LE L +LQ+N +++
Sbjct: 280 PNIVELSVGHNKLKQAFY-IPRNLEHL----------------------YLQNNEIEKMN 316
Query: 176 VSAAFKGLKSLEYLDLSFNQIARLPSGLPVS---------LLTLYLDNNKISN-----IP 221
++ + L Y L++ ++ + P+S + T+Y + +N +
Sbjct: 317 LTVMCPSIDPLHYHHLTYIRVDQNKLKEPISSYIFFCFPHIHTIYYGEQRSTNGQTIQLK 376
Query: 222 DEYFKRF 228
+ F+RF
Sbjct: 377 TQVFRRF 383
>gb|AAD04570.1| (AF104362) osteoadherin [Rattus norvegicus]
Length = 423
Score = 209 bits (527), Expect = 3e-53
Identities = 123/339 (36%), Positives = 189/339 (55%), Gaps = 28/339 (8%)
Query: 6 FTLFLALIGGTSGQYYDY------------DFPPSI-------YG----QSSPNCAPECN 42
+ LF + GQY Y D+ P YG Q+ CA EC
Sbjct: 8 YVLFFCFVVRVYGQYEAYQWDEDYEQEPSEDYEPEFQFHQNIEYGAPFYQNILGCAKECF 67
Query: 43 CPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVL 102
CP ++P++MYCD KLK++P +P I+ L L+ N I+ + +F N T L+ + L HN +
Sbjct: 68 CPTNFPTSMYCDNRKLKTIPDIPMHIQQLNLQFNDIEAVTADSFINATHLKEINLSHNKI 127
Query: 103 ENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL--GSFEGLVN 160
++ KI VF+KL L++LH++HNNL E PLPKSLE L L +N+I+ L + +GLVN
Sbjct: 128 KSQKIDYGVFAKLSNLQQLHLDHNNLEEFPFPLPKSLERLLLGYNEISTLPTHAMDGLVN 187
Query: 161 LTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISN 219
+T + L +N L + + L+ L L+L N++ +P GLP+SL+ L L+NN IS+
Sbjct: 188 VTMLDLCYNHLSDSTLKGKILSKLEKLMQLNLCNNRLESMPPGLPLSLMYLSLENNSISS 247
Query: 220 IPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTXXXXXXXX 279
IP++YF++ L LR+SHN+L D IP + FN+S+L+EL++ +NKLK
Sbjct: 248 IPEDYFQKLPKLHALRISHNKLED--IPYDIFNLSNLIELNVGHNKLKQAFYIPRNLEHL 305
Query: 280 XXXXXXXXKFDIKSFCKILGPLSYSKIKHLRLDGNRISE 318
++ C L PL + + +LR+D N++ E
Sbjct: 306 YLQNNEIQSINVTMMCPSLDPLHHHHLTYLRVDQNKLKE 344
Score = 56.2 bits (133), Expect = 5e-07
Identities = 44/133 (33%), Positives = 72/133 (54%), Gaps = 13/133 (9%)
Query: 57 KLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKL 115
+L+S+P +P + YL L NN I I E F+ + L L + HN LE+ I +F+ L
Sbjct: 223 RLESMPPGLPLSLMYLSLENNSISSIPEDYFQKLPKLHALRISHNKLED--IPYDIFN-L 279
Query: 116 KQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLG------SFEGLVN--LTFIHLQ 167
L +L++ HN L ++ +P++LE L L +N+I + S + L + LT++ +
Sbjct: 280 SNLIELNVGHNKLKQAFY-IPRNLEHLYLQNNEIQSINVTMMCPSLDPLHHHHLTYLRVD 338
Query: 168 HNRLKEDAVSAAF 180
N+LKE S F
Sbjct: 339 QNKLKEPISSYIF 351
Score = 45.7 bits (106), Expect = 7e-04
Identities = 45/202 (22%), Positives = 88/202 (43%), Gaps = 46/202 (22%)
Query: 51 MYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKG 109
++ D L+ P +P ++ L L N+I + A + + ++ L L +N L +S +KG
Sbjct: 146 LHLDHNNLEEFPFPLPKSLERLLLGYNEISTLPTHAMDGLVNVTMLDLCYNHLSDSTLKG 205
Query: 110 RVFSKLKQLKKLHINHNNLTESVGPLPKSL--------------ED----------LQLT 145
++ SKL++L +L++ +N L LP SL ED L+++
Sbjct: 206 KILSKLEKLMQLNLCNNRLESMPPGLPLSLMYLSLENNSISSIPEDYFQKLPKLHALRIS 265
Query: 146 HNKITKLG----SFEGLV-----------------NLTFIHLQHNRLKEDAVSAAFKGLK 184
HNK+ + + L+ NL ++LQ+N ++ V+ L
Sbjct: 266 HNKLEDIPYDIFNLSNLIELNVGHNKLKQAFYIPRNLEHLYLQNNEIQSINVTMMCPSLD 325
Query: 185 SLEYLDLSFNQIARLPSGLPVS 206
L + L++ ++ + P+S
Sbjct: 326 PLHHHHLTYLRVDQNKLKEPIS 347
>gb|AAC39259.1| (U67279) osteoadherin [Bos taurus]
Length = 422
Score = 208 bits (524), Expect = 7e-53
Identities = 113/301 (37%), Positives = 177/301 (58%), Gaps = 8/301 (2%)
Query: 19 QYYDYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQI 78
Q +Y+ P + Q + CA EC CP ++PS+MYCD KLK++P +P I+ +YL+ N+I
Sbjct: 47 QNINYEAP---FHQHTLGCASECFCPPNFPSSMYCDNRKLKTIPNIPAHIQQVYLQFNEI 103
Query: 79 DHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKS 138
+ + +F N T L+ + L HN +++ KI VF+ L L +LH+ HNNL + PLPKS
Sbjct: 104 EAVTADSFINATHLKEINLSHNKIKSQKIDHGVFATLPNLLQLHLQHNNLEDFPFPLPKS 163
Query: 139 LEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQ 195
LE + L +N+I++L + GLVNLT + L N++ + + ++ L L+L N+
Sbjct: 164 LERIFLGYNEISRLQTNAVNGLVNLTMLDLCFNKIDDSVLQEKVLAKMEKLMQLNLCNNR 223
Query: 196 IARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSS 255
+ +P GLP SL+ L L+NN IS+IP+ YF + L LR+SHN+L D IP N FN+S+
Sbjct: 224 LESMPPGLPSSLMYLSLENNSISSIPENYFNKLPKLHALRISHNKLQD--IPYNIFNLSN 281
Query: 256 LVELDLSYNKLKNIPTXXXXXXXXXXXXXXXXKFDIKSFCKILGPLSYSKIKHLRLDGNR 315
L+EL++ +NKLK ++ C + PL Y + H+R+D N+
Sbjct: 282 LIELNVGHNKLKQAFYIPRNLEHLYLENNEIENVNVTVMCPSVDPLHYHHLTHIRIDQNK 341
Query: 316 I 316
+
Sbjct: 342 L 342
>ref|NP_036180.1| osteomodulin; osteoadherin [Mus musculus]
dbj|BAA22790.1| (AB007848) osteomodulin [Mus musculus]
Length = 423
Score = 203 bits (511), Expect = 2e-51
Identities = 110/285 (38%), Positives = 170/285 (59%), Gaps = 5/285 (1%)
Query: 37 CAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLI 96
CA EC CP ++P++MYCD KLK++P++P I+ L L+ N I+ + +F N T L+ +
Sbjct: 62 CAKECFCPTNFPTSMYCDNRKLKTIPIIPMHIQQLNLQFNDIEAVTANSFINATHLKEIN 121
Query: 97 LDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL--GS 154
L HN +++ KI VF+KL L++LH+ HNNL E PLPKSLE L L +N+I+ L +
Sbjct: 122 LSHNKIKSQKIDYGVFAKLSNLQQLHLEHNNLEEFPFPLPKSLERLLLGYNEISILPTNA 181
Query: 155 FEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLD 213
+GLVN+T + L +N L + + ++ L L+L N++ +P GLP SL+ L L+
Sbjct: 182 MDGLVNVTMLDLCYNHLSDSMLKEKTLSKMEKLMQLNLCNNRLESMPLGLPSSLMYLSLE 241
Query: 214 NNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTXX 273
NN IS+IPD YF + L LR+SHN+L D IP + FN+S+L+EL++ +NKLK
Sbjct: 242 NNSISSIPDNYFDKLPKLHALRISHNKLED--IPYDIFNLSNLIELNVGHNKLKQAFYIP 299
Query: 274 XXXXXXXXXXXXXXKFDIKSFCKILGPLSYSKIKHLRLDGNRISE 318
++ C P+ + + +LR+D N++ E
Sbjct: 300 RNLEHLYLQNNEIESINVTMICPSPDPVHHHHLTYLRVDQNKLKE 344
Score = 55.0 bits (130), Expect = 1e-06
Identities = 41/133 (30%), Positives = 70/133 (51%), Gaps = 13/133 (9%)
Query: 57 KLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKL 115
+L+S+P+ +P + YL L NN I I + F+ + L L + HN LE+ I +F+ L
Sbjct: 223 RLESMPLGLPSSLMYLSLENNSISSIPDNYFDKLPKLHALRISHNKLED--IPYDIFN-L 279
Query: 116 KQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVN--------LTFIHLQ 167
L +L++ HN L ++ +P++LE L L +N+I + + LT++ +
Sbjct: 280 SNLIELNVGHNKLKQAFY-IPRNLEHLYLQNNEIESINVTMICPSPDPVHHHHLTYLRVD 338
Query: 168 HNRLKEDAVSAAF 180
N+LKE S F
Sbjct: 339 QNKLKEPISSYIF 351
>gb|AAC39516.1| (AF020291) fibromodulin [Oryctolagus cuniculus]
Length = 147
Score = 156 bits (390), Expect = 4e-37
Identities = 76/149 (51%), Positives = 109/149 (73%), Gaps = 4/149 (2%)
Query: 123 INHNNLTESVGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAF 180
++HNNLT GPLP+SL +L L HN+I+++ + EGL NLT ++LQHN ++E V ++
Sbjct: 1 LDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQE--VGSSM 58
Query: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNE 240
+GL+SL LDLS+N + R+P GLP +L LYL++N + +PD YF+ L Y+RLSHN
Sbjct: 59 RGLRSLILLDLSYNHLRRVPDGLPSALEQLYLEHNNVYTVPDSYFRGSPKLLYVRLSHNS 118
Query: 241 LADSGIPGNSFNVSSLVELDLSYNKLKNI 269
L +SG+ N+FN SSL+ELDLSYN+L+ I
Sbjct: 119 LTNSGLASNTFNSSSLLELDLSYNQLQKI 147
Score = 68.7 bits (165), Expect = 9e-11
Identities = 42/138 (30%), Positives = 69/138 (49%), Gaps = 5/138 (3%)
Query: 64 VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHI 123
+P ++ L+L +NQI + A E + +L L L HN ++ G L+ L L +
Sbjct: 13 LPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQE---VGSSMRGLRSLILLDL 69
Query: 124 NHNNLTESVGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFK 181
++N+L LP +LE L L HN + + F G L ++ L HN L +++
Sbjct: 70 SYNHLRRVPDGLPSALEQLYLEHNNVYTVPDSYFRGSPKLLYVRLSHNSLTNSGLASNTF 129
Query: 182 GLKSLEYLDLSFNQIARL 199
SL LDLS+NQ+ ++
Sbjct: 130 NSSSLLELDLSYNQLQKI 147
Score = 60.9 bits (145), Expect = 2e-08
Identities = 32/80 (40%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Query: 191 LSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNS 250
L N + R+P LP SL L+LD+N+IS +P+ + L L L HNE+ + G +
Sbjct: 1 LDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG--SSM 58
Query: 251 FNVSSLVELDLSYNKLKNIP 270
+ SL+ LDLSYN L+ +P
Sbjct: 59 RGLRSLILLDLSYNHLRRVP 78
Score = 35.6 bits (80), Expect = 0.83
Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Query: 58 LKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLK 116
L+ VP +P ++ LYL +N + + + F L ++ L HN L NS + F+
Sbjct: 74 LRRVPDGLPSALEQLYLEHNNVYTVPDSYFRGSPKLLYVRLSHNSLTNSGLASNTFNS-S 132
Query: 117 QLKKLHINHNNL 128
L +L +++N L
Sbjct: 133 SLLELDLSYNQL 144
>gb|AAF19154.1| (AF159383) fibromodulin [Sus scrofa]
Length = 147
Score = 154 bits (385), Expect = 1e-36
Identities = 74/149 (49%), Positives = 110/149 (73%), Gaps = 4/149 (2%)
Query: 123 INHNNLTESVGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAF 180
++HNNLT GPLP+SL +L L HN+I+++ + EGL NLT ++LQHN ++E V ++
Sbjct: 1 LDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQE--VGSSM 58
Query: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNE 240
+GL+SL LDLS+N + ++P GLP +L LYL++N + ++PD YF+ L Y+RLSHN
Sbjct: 59 RGLRSLILLDLSYNHLRKVPDGLPSALEQLYLEHNNVYSVPDSYFRGSPKLLYVRLSHNS 118
Query: 241 LADSGIPGNSFNVSSLVELDLSYNKLKNI 269
L ++G+ N+FN SSL+ELDLSYN+L+ I
Sbjct: 119 LTNNGLASNTFNSSSLLELDLSYNQLQKI 147
Score = 69.9 bits (168), Expect = 4e-11
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 5/138 (3%)
Query: 64 VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHI 123
+P ++ L+L +NQI + A E + +L L L HN ++ G L+ L L +
Sbjct: 13 LPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQE---VGSSMRGLRSLILLDL 69
Query: 124 NHNNLTESVGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFK 181
++N+L + LP +LE L L HN + + F G L ++ L HN L + +++
Sbjct: 70 SYNHLRKVPDGLPSALEQLYLEHNNVYSVPDSYFRGSPKLLYVRLSHNSLTNNGLASNTF 129
Query: 182 GLKSLEYLDLSFNQIARL 199
SL LDLS+NQ+ ++
Sbjct: 130 NSSSLLELDLSYNQLQKI 147
Score = 60.9 bits (145), Expect = 2e-08
Identities = 32/80 (40%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Query: 191 LSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNS 250
L N + R+P LP SL L+LD+N+IS +P+ + L L L HNE+ + G +
Sbjct: 1 LDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVG--SSM 58
Query: 251 FNVSSLVELDLSYNKLKNIP 270
+ SL+ LDLSYN L+ +P
Sbjct: 59 RGLRSLILLDLSYNHLRKVP 78
Score = 35.2 bits (79), Expect = 1.1
Identities = 20/72 (27%), Positives = 37/72 (50%), Gaps = 2/72 (2%)
Query: 58 LKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLK 116
L+ VP +P ++ LYL +N + + + F L ++ L HN L N+ + F+
Sbjct: 74 LRKVPDGLPSALEQLYLEHNNVYSVPDSYFRGSPKLLYVRLSHNSLTNNGLASNTFNS-S 132
Query: 117 QLKKLHINHNNL 128
L +L +++N L
Sbjct: 133 SLLELDLSYNQL 144
>ref|NP_031859.1| decorin [Mus musculus]
sp|P28654|PGS2_MOUSE BONE PROTEOGLYCAN II PRECURSOR (PG-S2) (DECORIN) (PG40)
pir||A55454 decorin precursor - mouse
emb|CAA37876.1| (X53929) decorin (PGII) [Mus musculus]
Length = 354
Score = 141 bits (351), Expect = 1e-32
Identities = 101/308 (32%), Positives = 148/308 (47%), Gaps = 13/308 (4%)
Query: 37 CAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWL 95
C C C + + C +L L VP PP L L+NN+I I E AF+N+ DL L
Sbjct: 49 CPYRCQC---HLRVVQCSDLGLDKVPWDFPPDTTLLDLQNNKITEIKEGAFKNLKDLHTL 105
Query: 96 ILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL--G 153
IL +N + SKI F L +L++L+++ N L E +P++L++L++ N+ITKL
Sbjct: 106 ILVNNKI--SKISPEAFKPLVKLERLYLSKNQLKELPEKMPRTLQELRVHENEITKLRKS 163
Query: 154 SFEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYL 212
F GL N+ I L N LK + + AF+GLKSL Y+ +S I +P GLP SL ++L
Sbjct: 164 DFNGLNNVLVIELGGNPLKNSGIENGAFQGLKSLSYIRISDTNITAIPQGLPTSLTEVHL 223
Query: 213 DNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTX 272
D NKI+ + K L L LS N + G+ NV L EL L NKL +P
Sbjct: 224 DGNKITKVDAPSLKGLINLSKLGLSFNSITVME-NGSLANVPHLRELHLDNNKLLRVPAG 282
Query: 273 XXXXXXXXXXXXXXXKFDI---KSFCKILGPLSYSKIKHLRLDGNRISETSLPPDMYECL 329
FC+ P + + L GN + + P+ + C+
Sbjct: 283 LAQHKYIQVVYLHNNNISAVGQNDFCRAGHPSRKASYSAVSLYGNPVRYWEIFPNTFRCV 342
Query: 330 RVANEVTL 337
V + + L
Sbjct: 343 YVRSAIQL 350
>sp|P28675|PGS2_CHICK BONE PROTEOGLYCAN II PRECURSOR (PG-S2) (DECORIN)
pir||S24317 decorin precursor - chicken
emb|CAA45318.1| (X63797) decorin [Gallus gallus]
Length = 357
Score = 136 bits (338), Expect = 5e-31
Identities = 103/314 (32%), Positives = 155/314 (48%), Gaps = 21/314 (6%)
Query: 35 PNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQ 93
P C C C + + C +L L+ VP +PP L L+NN+I I E F+N+ +L
Sbjct: 50 PVCPFRCQC---HLRVVQCSDLGLERVPKDLPPDTTLLDLQNNKITEIKEGDFKNLKNLH 106
Query: 94 WLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLG 153
LIL +N + SKI F+ LK+L++L+++ NNL E +PKSL++++ N+I+KL
Sbjct: 107 ALILVNNKI--SKISPAAFAPLKKLERLYLSKNNLKELPENMPKSLQEIRAHENEISKLR 164
Query: 154 S--FEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTL 210
F GL + + L N LK + + AF+G+K L Y+ ++ I +P GLP SL L
Sbjct: 165 KAVFNGLNQVIVLELGTNPLKSSGIENGAFQGMKRLSYIRIADTNITSIPKGLPPSLTEL 224
Query: 211 YLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIP 270
+LD NKIS I E L L LS N ++ S G+ NV L EL L+ N+L +P
Sbjct: 225 HLDGNKISKIDAEGLSGLTNLAKLGLSFNSIS-SVENGSLNNVPHLRELHLNNNELVRVP 283
Query: 271 TXXXXXXXXXXXXXXXXK---FDIKSFCKILGPLSYSKIK----HLRLDGNRISETSLPP 323
+ K I FC PL Y+ K + L N + + P
Sbjct: 284 SGLGEHKYIQVVYLHNNKIASIGINDFC----PLGYNTKKATYSGVSLFSNPVQYWEIQP 339
Query: 324 DMYECLRVANEVTL 337
+ C+ + V +
Sbjct: 340 SAFRCIHERSAVQI 353
>ref|NP_001911.1| decorin [Homo sapiens]
sp|P07585|PGS2_HUMAN BONE PROTEOGLYCAN II PRECURSOR (PG-S2) (DECORIN) (PG40)
pir||NBHUC8 decorin precursor - human
gb|AAB00774.1| (M14219) proteoglycan core protein [Homo sapiens]
gb|AAD44713.1| (AF138300) decorin variant A [Homo sapiens]
Length = 359
Score = 134 bits (333), Expect = 2e-30
Identities = 99/323 (30%), Positives = 153/323 (46%), Gaps = 17/323 (5%)
Query: 22 DYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDH 80
D DF PS+ P C C C + + C +L L VP +PP L L+NN+I
Sbjct: 43 DRDFEPSL----GPVCPFRCQC---HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITE 95
Query: 81 IDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLE 140
I + F+N+ +L LIL +N + SK+ F+ L +L++L+++ N L E +PK+L+
Sbjct: 96 IKDGDFKNLKNLHALILVNNKI--SKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQ 153
Query: 141 DLQLTHNKITKLG--SFEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIA 197
+L+ N+ITK+ +F GL + I L N LK + + AF+G+K L Y+ ++ I
Sbjct: 154 ELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNIT 213
Query: 198 RLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLV 257
+P GLP SL L+LD NKIS + K N L L LS N ++ + G+ N L
Sbjct: 214 SIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSIS-AVDNGSLANTPHLR 272
Query: 258 ELDLSYNKLKNIPTXXXXXXXXXXXXXXXXKFDI---KSFCKILGPLSYSKIKHLRLDGN 314
EL L NKL +P + FC + + L N
Sbjct: 273 ELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSN 332
Query: 315 RISETSLPPDMYECLRVANEVTL 337
+ + P + C+ V + + L
Sbjct: 333 PVQYWEIQPSTFRCVYVRSAIQL 355
>sp|Q01129|PGS2_RAT BONE PROTEOGLYCAN II PRECURSOR (PG-S2) (DECORIN) (PG40) (DERMATAN
SULFATE PROTEOGLYCAN-II) (DSPG)
pir||S29145 decorin precursor - rat
emb|CAA78170.1| (Z12298) dermatan sulfate proteoglycan-II (decorin) [Rattus rattus]
Length = 354
Score = 131 bits (327), Expect = 9e-30
Identities = 90/238 (37%), Positives = 127/238 (52%), Gaps = 10/238 (4%)
Query: 37 CAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWL 95
C C C + + C +L L VP PP L L+NN+I I E AF+N+ DL L
Sbjct: 49 CPYRCQC---HLRVVQCSDLGLDKVPWEFPPDTTLLDLQNNKITEIKEGAFKNLKDLHTL 105
Query: 96 ILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGS- 154
IL +N + SKI F L +L++L+++ N+L E LPK+L++L+L N+ITKL
Sbjct: 106 ILVNNKI--SKISPEAFKPLVKLERLYLSKNHLKELPEKLPKTLQELRLHDNEITKLKKS 163
Query: 155 -FEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYL 212
F GL + I L N LK + + A +G+K L Y+ +S I +P GLP S+ L+L
Sbjct: 164 VFNGLNRMIVIELGGNPLKNSGIENGALQGMKGLGYIRISDTNITAIPQGLPTSISELHL 223
Query: 213 DNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIP 270
D NKI+ + K + L L LS N + G+ NV L EL L NKL +P
Sbjct: 224 DGNKIAKVDAASLKGMSNLSKLGLSFNSITVVE-NGSLANVPHLRELHLDNNKLLRVP 280
>emb|CAA42519.1| (X59859) decorin [Rattus norvegicus]
Length = 344
Score = 131 bits (327), Expect = 9e-30
Identities = 90/238 (37%), Positives = 127/238 (52%), Gaps = 10/238 (4%)
Query: 37 CAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWL 95
C C C + + C +L L VP PP L L+NN+I I E AF+N+ DL L
Sbjct: 39 CPYRCQC---HLRVVQCSDLGLDKVPWEFPPDTTLLDLQNNKITEIKEGAFKNLKDLHTL 95
Query: 96 ILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGS- 154
IL +N + SKI F L +L++L+++ N+L E LPK+L++L+L N+ITKL
Sbjct: 96 ILVNNKI--SKISPEAFKPLVKLERLYLSKNHLKELPEKLPKTLQELRLHDNEITKLKKS 153
Query: 155 -FEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYL 212
F GL + I L N LK + + A +G+K L Y+ +S I +P GLP S+ L+L
Sbjct: 154 VFNGLNRMIVIELGGNPLKNSGIENGALQGMKGLGYIRISDTNITAIPQGLPTSISELHL 213
Query: 213 DNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIP 270
D NKI+ + K + L L LS N + G+ NV L EL L NKL +P
Sbjct: 214 DGNKIAKVDAASLKGMSNLSKLGLSFNSITVVE-NGSLANVPHLRELHLDNNKLLRVP 270
>gb|AAA52301.1| (L01131) decorin [Homo sapiens]
Length = 347
Score = 131 bits (325), Expect = 2e-29
Identities = 90/252 (35%), Positives = 135/252 (52%), Gaps = 14/252 (5%)
Query: 22 DYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDH 80
D DF PS+ P C C C + + C +L L VP +PP L L+NN+I
Sbjct: 43 DRDFEPSL----GPVCPFRCQC---HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITE 95
Query: 81 IDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLE 140
I + F+N+ +L LIL +N + SK+ F+ L +L++L+++ N L E +PK+L+
Sbjct: 96 IKDGDFKNLKNLHALILVNNKI--SKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQ 153
Query: 141 DLQLTHNKITKLG--SFEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIA 197
+L+ N+ITK+ +F GL + I L N LK + + AF+G+K L Y+ ++ I
Sbjct: 154 ELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNIT 213
Query: 198 RLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLV 257
+P GLP SL L+LD NKIS + K N L L LS N ++ + G+ N L
Sbjct: 214 SIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSIS-AVDNGSLANTPHLR 272
Query: 258 ELDLSYNKLKNI 269
EL L NKL +
Sbjct: 273 ELHLDNNKLTRV 284
>sp|Q9XSD9|PGS2_PIG BONE PROTEOGLYCAN II PRECURSOR (PG-S2) (DECORIN)
gb|AAD23578.1|AF125537_1 (AF125537) decorin [Sus scrofa]
Length = 360
Score = 129 bits (321), Expect = 5e-29
Identities = 85/240 (35%), Positives = 129/240 (53%), Gaps = 10/240 (4%)
Query: 35 PNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQ 93
P C C C + + C +L L VP +PP L L+NN+I I + F+N+ +L
Sbjct: 53 PMCPFRCQC---HLRVVQCSDLGLDKVPKDLPPDTALLDLQNNKITEIKDGDFKNLKNLH 109
Query: 94 WLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLG 153
LIL +N + SKI F+ L +L++L+++ N L E +PK+L++L++ N+ITK+
Sbjct: 110 TLILINNKI--SKISPGAFAPLVKLERLYLSKNQLKELPEKMPKTLQELRVHENEITKVR 167
Query: 154 S--FEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTL 210
F GL + + L N LK + + AF+G+K L Y+ ++ I +P GLP SL L
Sbjct: 168 KAVFNGLNQMIVVELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITTIPQGLPPSLTEL 227
Query: 211 YLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIP 270
+LD NKIS + K N L L L N ++ G+ N L EL L+ NKL +P
Sbjct: 228 HLDGNKISKVDAASLKGLNNLAKLGLGFNSISTVD-NGSLANTPHLRELHLNNNKLNKVP 286
Score = 41.8 bits (96), Expect = 0.011
Identities = 27/103 (26%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
Query: 55 ELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFS 113
+ + ++P +PP + L+L N+I +D + + + +L L L N + S + +
Sbjct: 210 DTNITTIPQGLPPSLTELHLDGNKISKVDAASLKGLNNLAKLGLGFNSI--STVDNGSLA 267
Query: 114 KLKQLKKLHINHNNLTESVGPLP--KSLEDLQLTHNKITKLGS 154
L++LH+N+N L + G L K ++ + L +N I+ +GS
Sbjct: 268 NTPHLRELHLNNNKLNKVPGGLAEHKYIQVVYLHNNNISAVGS 310
>sp|P21793|PGS2_BOVIN BONE PROTEOGLYCAN II PRECURSOR (PG-S2) (DECORIN)
pir||S06280 decorin precursor - bovine
emb|CAA68702.1| (Y00712) precursor polypeptide (AA -30 to 330) [Bos taurus]
Length = 360
Score = 129 bits (321), Expect = 5e-29
Identities = 85/240 (35%), Positives = 132/240 (54%), Gaps = 10/240 (4%)
Query: 35 PNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQ 93
P C C C + + C +L L+ VP +PP L L+NN+I I + F+N+ +L
Sbjct: 53 PVCPFRCQC---HLRVVQCSDLGLEKVPKDLPPDTALLDLQNNKITEIKDGDFKNLKNLH 109
Query: 94 WLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLG 153
LIL +N + SKI F+ L +L++L+++ N L E +PK+L++L++ N+ITK+
Sbjct: 110 TLILINNKI--SKISPGAFAPLVKLERLYLSKNQLKELPEKMPKTLQELRVHENEITKVR 167
Query: 154 S--FEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTL 210
F GL + + L N LK + + AF+G+K L Y+ ++ I +P GLP SL L
Sbjct: 168 KSVFNGLNQMIVVELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITTIPQGLPPSLTEL 227
Query: 211 YLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIP 270
+LD NKI+ + K N L L LS N ++ + G+ N L EL L+ NKL +P
Sbjct: 228 HLDGNKITKVDAASLKGLNNLAKLGLSFNSIS-AVDNGSLANTPHLRELHLNNNKLAKVP 286
Score = 41.0 bits (94), Expect = 0.019
Identities = 26/103 (25%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
Query: 55 ELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFS 113
+ + ++P +PP + L+L N+I +D + + + +L L L N + S + +
Sbjct: 210 DTNITTIPQGLPPSLTELHLDGNKITKVDAASLKGLNNLAKLGLSFNSI--SAVDNGSLA 267
Query: 114 KLKQLKKLHINHNNLTESVGPLP--KSLEDLQLTHNKITKLGS 154
L++LH+N+N L + G + K ++ + L +N I+ +GS
Sbjct: 268 NTPHLRELHLNNNKLAKVPGGVADHKYIQVVYLHNNNISAIGS 310
>gb|AAF00585.1|AF125041_1 (AF125041) decorin [Ovis aries]
Length = 360
Score = 129 bits (320), Expect = 6e-29
Identities = 85/240 (35%), Positives = 132/240 (54%), Gaps = 10/240 (4%)
Query: 35 PNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQ 93
P C C C + + C +L L+ VP +PP L L+NN+I I + F+N+ +L
Sbjct: 53 PVCPFRCQC---HLRVVQCSDLGLEKVPKDLPPDTALLDLQNNKITEIKDGDFKNLKNLH 109
Query: 94 WLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLG 153
LIL +N + SKI F+ L +L++L+++ N L E +PK+L++L++ N+ITK+
Sbjct: 110 TLILINNKI--SKISPGAFAPLVKLERLYLSKNQLKELPEKMPKTLQELRVHENEITKVR 167
Query: 154 S--FEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTL 210
F GL + + L N LK + + AF+G+K L Y+ ++ I +P GLP SL L
Sbjct: 168 KSVFNGLNQMIVVELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITTIPQGLPPSLTEL 227
Query: 211 YLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIP 270
+LD NKI+ + K N L L LS N ++ + G+ N L EL L+ NKL +P
Sbjct: 228 HLDGNKITKVDAASLKGLNNLAKLGLSFNSIS-AVDNGSLANTPHLRELHLNNNKLVKVP 286
Score = 42.2 bits (97), Expect = 0.008
Identities = 27/103 (26%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
Query: 55 ELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFS 113
+ + ++P +PP + L+L N+I +D + + + +L L L N + S + +
Sbjct: 210 DTNITTIPQGLPPSLTELHLDGNKITKVDAASLKGLNNLAKLGLSFNSI--SAVDNGSLA 267
Query: 114 KLKQLKKLHINHNNLTESVGPLP--KSLEDLQLTHNKITKLGS 154
L++LH+N+N L + G L K ++ + L +N I+ +GS
Sbjct: 268 NTPHLRELHLNNNKLVKVPGGLADHKYIQVVYLHNNNISAIGS 310
>sp|Q28888|PGS2_RABIT BONE PROTEOGLYCAN II PRECURSOR (PG-S2) (DECORIN)
pir||I47020 decorin - rabbit
gb|AAB33083.1| (S76584) decorin=proteoglycan [rabbits, corneal stromal cells,
Peptide, 360 aa] [Oryctolagus cuniculus]
Length = 360
Score = 129 bits (320), Expect = 6e-29
Identities = 87/240 (36%), Positives = 131/240 (54%), Gaps = 10/240 (4%)
Query: 35 PNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQ 93
P C C C + + C +L L VP +PP L L+NN+I I + F+N+ +L
Sbjct: 53 PVCPFRCQC---HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLH 109
Query: 94 WLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLG 153
LIL +N + SKI F+ L +L++L+++ N+L E +PKSL++L+ N+ITK+
Sbjct: 110 ALILVNNKI--SKISPGAFTPLVKLERLYLSKNHLKELPEKMPKSLQELRAHENEITKVR 167
Query: 154 S--FEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTL 210
F G+ + I L N LK + + AF+G+K L Y+ ++ I +P GLP SL L
Sbjct: 168 KSVFSGMNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITTIPQGLPPSLTEL 227
Query: 211 YLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIP 270
+LD NKI+ I K N L L LS N+++ + G+ N L EL L NKL +P
Sbjct: 228 HLDGNKITKIDASSLKGLNNLAKLGLSFNDIS-AVDNGSLANAPHLRELHLDNNKLIRVP 286
>gb|AAC04315.1| (U03394) decorin [Oryctolagus cuniculus]
Length = 321
Score = 129 bits (320), Expect = 6e-29
Identities = 87/240 (36%), Positives = 131/240 (54%), Gaps = 10/240 (4%)
Query: 35 PNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQ 93
P C C C + + C +L L VP +PP L L+NN+I I + F+N+ +L
Sbjct: 16 PVCPFRCQC---HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLH 72
Query: 94 WLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLG 153
LIL +N + SKI F+ L +L++L+++ N+L E +PKSL++L+ N+ITK+
Sbjct: 73 ALILVNNKI--SKISPGAFTPLVKLERLYLSKNHLKELPEKMPKSLQELRAHENEITKVR 130
Query: 154 S--FEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTL 210
F G+ + I L N LK + + AF+G+K L Y+ ++ I +P GLP SL L
Sbjct: 131 KSVFSGMNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITTIPQGLPPSLTEL 190
Query: 211 YLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIP 270
+LD NKI+ I K N L L LS N+++ + G+ N L EL L NKL +P
Sbjct: 191 HLDGNKITKIDASSLKGLNNLAKLGLSFNDIS-AVDNGSLANAPHLRELHLDNNKLIRVP 249
>dbj|BAA90246.1| (AB037269) biglycan [Xenopus laevis]
Length = 368
Score = 126 bits (313), Expect = 4e-28
Identities = 89/238 (37%), Positives = 132/238 (55%), Gaps = 11/238 (4%)
Query: 37 CAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWL 95
C C C + + C +L L S+P +P L L+NN+I I + F+ +T+L L
Sbjct: 63 CPFGCQC---HLRVVQCSDLGLTSIPKNLPKDTTLLDLQNNKITEIKKDDFKGLTNLYAL 119
Query: 96 ILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL--G 153
++ +N + SKI + F L++++KL+I+ NNL E LPKSL +L++ NKI K+ G
Sbjct: 120 VIVNNKI--SKINEKAFEPLQKMQKLYISKNNLEEIPKNLPKSLVELRIHENKIKKVPKG 177
Query: 154 SFEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYL 212
F GL N+ I + N L+ + A AF GLK L YL +S +++ +P GLP +L L+L
Sbjct: 178 VFSGLKNMNCIEMGGNPLENGGIEAGAFDGLK-LNYLRVSEAKLSGIPKGLPSTLNELHL 236
Query: 213 DNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIP 270
DNNKI I E ++ +L L L HN + SF + L EL L NKL +P
Sbjct: 237 DNNKIQAIEKEDLSQYASLYRLGLGHNNIRMIENGSLSF-MPVLRELHLDNNKLSKVP 293
>sp|O46542|PGS2_HORSE BONE PROTEOGLYCAN II PRECURSOR (PG-S2) (DECORIN) (DERMATAN SULFATE
PROTEOGLYCAN II) (DS-PGII)
gb|AAB92652.1| (AF038127) dermatan sulfate proteoglycan II [Equus caballus]
Length = 360
Score = 125 bits (312), Expect = 5e-28
Identities = 84/240 (35%), Positives = 131/240 (54%), Gaps = 10/240 (4%)
Query: 35 PNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQ 93
P C C C + + C +L L VP +PP L L+NN+I I + F+N+ +L
Sbjct: 53 PVCPFRCQC---HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLH 109
Query: 94 WLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLG 153
LIL +N + SKI F+ L +L++L+++ N+L E +PK+L++L++ N+ITK+
Sbjct: 110 ALILVNNKI--SKISPGAFTPLVKLERLYLSKNHLKELPEKMPKTLQELRVHENEITKVR 167
Query: 154 S--FEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTL 210
F GL + + L N LK + + AF+G+K L Y+ ++ I +P GLP SL L
Sbjct: 168 KAVFNGLNQMIVVELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITTIPPGLPPSLTEL 227
Query: 211 YLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIP 270
+LD NKI+ + + N L L LS N ++ + G+ N L EL L NKL +P
Sbjct: 228 HLDGNKITKVDAASLRGLNNLAKLGLSFNSIS-AVDNGSLANTPHLRELHLDNNKLIKVP 286
>sp|Q29393|PGS2_CANFA BONE PROTEOGLYCAN II PRECURSOR (PG-S2) (DECORIN)
gb|AAB51245.1| (U83141) decorin [Canis familiaris]
Length = 360
Score = 125 bits (311), Expect = 7e-28
Identities = 84/240 (35%), Positives = 129/240 (53%), Gaps = 10/240 (4%)
Query: 35 PNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQ 93
P C C C + + C +L L VP +PP L L+NN+I I + F+N+ +L
Sbjct: 53 PVCPFRCQC---HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLH 109
Query: 94 WLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLG 153
LIL +N + SKI F+ L +L++L+++ N+L E +PK+L++L+ N+ITK+
Sbjct: 110 TLILVNNKI--SKISPGAFTPLLKLERLYLSKNHLKELPEKMPKTLQELRAHENEITKVR 167
Query: 154 S--FEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTL 210
F GL + + L N LK + + AF+G+K L Y+ ++ I +P GLP SL L
Sbjct: 168 KAVFNGLNQMIVVELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITTIPQGLPPSLTEL 227
Query: 211 YLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIP 270
+L+ NKI+ + K N L L LS N ++ + G N L EL L NKL +P
Sbjct: 228 HLEGNKITKVDASSLKGLNNLAKLGLSFNSIS-AVDNGTLANTPHLRELHLDNNKLIRVP 286
>gb|AAD33862.1|AF140270_1 (AF140270) decorin [Sus scrofa]
Length = 322
Score = 123 bits (306), Expect = 3e-27
Identities = 83/237 (35%), Positives = 126/237 (53%), Gaps = 10/237 (4%)
Query: 35 PNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQ 93
P C C C + + C +L L VP +PP L L+NN+I I + F+N+ +L
Sbjct: 53 PMCPFRCQC---HLRVVQCSDLGLDKVPKDLPPDTALLDLQNNKITEIKDGDFKNLKNLH 109
Query: 94 WLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLG 153
LIL +N + SKI F+ L +L++L+++ N L E +PK+L++L++ N+ITK+
Sbjct: 110 TLILINNKI--SKISPGAFAPLVKLERLYLSKNQLKELPEKMPKTLQELRVHENEITKVR 167
Query: 154 S--FEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTL 210
F GL + + L N LK + + AF+G+K L Y+ ++ I +P GLP SL L
Sbjct: 168 KAVFNGLNQMIVVELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITTIPQGLPPSLTEL 227
Query: 211 YLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLK 267
+LD NKIS + K N L L L N ++ G+ N L EL L+ N K
Sbjct: 228 HLDGNKISKVDAASLKGLNNLAKLGLGFNSISTVD-NGSLANTPHLRELHLNNNNTK 283
>ref|NP_001384.1| extracellular matrix protein 2 [Homo sapiens]
dbj|BAA33958.1| (AB011792) extracellular matrix protein [Homo sapiens]
Length = 699
Score = 122 bits (302), Expect = 8e-27
Identities = 79/233 (33%), Positives = 125/233 (52%), Gaps = 4/233 (1%)
Query: 43 CPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVL 102
C SY + + + + P+ P I L L N I I ++AF + +L+ L L N +
Sbjct: 320 CSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNI 379
Query: 103 ENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLG--SFEGLVN 160
+S I + F LK+L +L+++ NNL + LP +LE+L++ N + + S L
Sbjct: 380 TSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQ 439
Query: 161 LTFIHLQHNRLKEDAVS-AAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISN 219
L + L+ N L E V+ AFK LKSL YL L N+ +P GLP S+ LYL+NN+I
Sbjct: 440 LVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEE 499
Query: 220 IPDEYFKRFNALQYLRLSHNELADSGI-PGNSFNVSSLVELDLSYNKLKNIPT 271
I + F + + L +N++ ++ I P N +L +DLSYNKL ++P+
Sbjct: 500 ITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPS 552
Score = 78.8 bits (191), Expect = 8e-14
Identities = 61/209 (29%), Positives = 105/209 (50%), Gaps = 13/209 (6%)
Query: 57 KLKSVPMVPPG-IKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKL 115
K + +P PG I+ LYL NNQI+ I E F + + ++L +N +E ++I +
Sbjct: 475 KFRIIPQGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQ 534
Query: 116 KQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSF---EGLVNLTFIHLQHNRLK 172
+ L+ + +++N L LPKSL L L N+I ++ + L +++L N+L
Sbjct: 535 ENLESIDLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLA 594
Query: 173 EDAVS--AAFKGLKSLEYLDLSFNQIARLPSGLP--VSLLTLYLDNNKISNI-PDEYFKR 227
+D + + + SL L L N + +P G+ +L L L+NNKI NI P+E
Sbjct: 595 DDGMDRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEICNA 654
Query: 228 ----FNALQYLRLSHNELADSGIPGNSFN 252
+ L++L L +N + IP +F+
Sbjct: 655 EEDDDSNLEHLHLENNYIKIREIPSYTFS 683
Score = 42.6 bits (98), Expect = 0.006
Identities = 40/156 (25%), Positives = 66/156 (41%), Gaps = 29/156 (18%)
Query: 198 RLPSGLPVS---------------------LLTLYLDNNKISNIPDEYFKRFNALQYLRL 236
RLPSG +S + +L L N I++IPDE F L+ L L
Sbjct: 315 RLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDL 374
Query: 237 SHNELADSGIPGNSFN-VSSLVELDLSYNKLKNIPTXXXXXXXXXXXXXXXXK-FDIKSF 294
S N + SGI +F + L+ L++ N L IP+ + D +S
Sbjct: 375 SKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESL 434
Query: 295 CKILGPLSYSKIKHLRLDGNRISETSLPPDMYECLR 330
+ +++ L L+GN +SE ++ P ++ L+
Sbjct: 435 SDL------NQLVTLELEGNNLSEANVNPLAFKPLK 464
>ref|NP_001702.1| biglycan [Homo sapiens]
sp|P21810|PGS1_HUMAN BONE/CARTILAGE PROTEOGLYCAN I PRECURSOR (BIGLYCAN) (PG-S1)
pir||BGHUN biglycan precursor - human
gb|AAA36009.1| (J04599) proteoglycan I precursor [Homo sapiens]
gb|AAF33530.1|U82695_3 (U82695) biglycan [Homo sapiens]
Length = 368
Score = 120 bits (299), Expect = 2e-26
Identities = 90/250 (36%), Positives = 134/250 (53%), Gaps = 11/250 (4%)
Query: 26 PPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEK 84
P S+ S C C+C + + C +L LKSVP + P L L+NN I + +
Sbjct: 52 PDSVTPTYSAMCPFGCHC---HLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKD 108
Query: 85 AFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQL 144
F+ + L L+L +N + SKI + FS L++L+KL+I+ N+L E LP SL +L++
Sbjct: 109 DFKGLQHLYALVLVNNKI--SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRI 166
Query: 145 THNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVS-AAFKGLKSLEYLDLSFNQIARLPS 201
N+I K+ G F GL N+ I + N L+ AF GLK L YL +S ++ +P
Sbjct: 167 HDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPK 225
Query: 202 GLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDL 261
LP +L L+LD+NKI I E R++ L L L HN++ SF + +L EL L
Sbjct: 226 DLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF-LPTLRELHL 284
Query: 262 SYNKLKNIPT 271
NKL +P+
Sbjct: 285 DNNKLARVPS 294
>sp|O46390|PGS1_SHEEP BONE/CARTILAGE PROTEOGLYCAN I PRECURSOR (BIGLYCAN) (PG-S1)
gb|AAB87988.1| (AF034842) biglycan precursor [Ovis aries]
Length = 369
Score = 119 bits (296), Expect = 4e-26
Identities = 98/315 (31%), Positives = 150/315 (47%), Gaps = 17/315 (5%)
Query: 22 DYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDH 80
D D P Y S C C+C + + C +L LK+VP + P L L+NN I
Sbjct: 52 DLDSLPPTY---SAMCPFGCHC---HLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISE 105
Query: 81 IDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLE 140
+ + F+ + L L+L +N + SKI + FS L++L+KL+I+ N+L E LP SL
Sbjct: 106 LRKDDFKGLQHLYALVLVNNKI--SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLV 163
Query: 141 DLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVS-AAFKGLKSLEYLDLSFNQIA 197
+L++ N+I K+ G F GL N+ I + N L+ AF GLK L YL +S ++
Sbjct: 164 ELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLT 222
Query: 198 RLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLV 257
+P LP +L L+LD+NKI I E R++ L L L HN++ SF + +L
Sbjct: 223 GIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF-LPTLR 281
Query: 258 ELDLSYNKLKNIPT---XXXXXXXXXXXXXXXXKFDIKSFCKILGPLSYSKIKHLRLDGN 314
EL L NKL +P K + FC + + + + L N
Sbjct: 282 ELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNN 341
Query: 315 RISETSLPPDMYECL 329
+ + P + C+
Sbjct: 342 PVPYWEVQPATFRCV 356
>pir||S32559 biglycan precursor - bovine
Length = 369
Score = 119 bits (296), Expect = 4e-26
Identities = 98/315 (31%), Positives = 150/315 (47%), Gaps = 17/315 (5%)
Query: 22 DYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDH 80
D D P Y S C C+C + + C +L LK+VP + P L L+NN I
Sbjct: 52 DLDSLPPTY---SAMCPFGCHC---HLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISE 105
Query: 81 IDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLE 140
+ + F+ + L L+L +N + SKI + FS L++L+KL+I+ N+L E LP SL
Sbjct: 106 LRKDDFKGLQHLYALVLVNNKI--SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLV 163
Query: 141 DLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVS-AAFKGLKSLEYLDLSFNQIA 197
+L++ N+I K+ G F GL N+ I + N L+ AF GLK L YL +S ++
Sbjct: 164 ELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLT 222
Query: 198 RLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLV 257
+P LP +L L+LD+NKI I E R++ L L L HN++ SF + +L
Sbjct: 223 GIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF-LPTLR 281
Query: 258 ELDLSYNKLKNIPT---XXXXXXXXXXXXXXXXKFDIKSFCKILGPLSYSKIKHLRLDGN 314
EL L NKL +P K + FC + + + + L N
Sbjct: 282 ELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNN 341
Query: 315 RISETSLPPDMYECL 329
+ + P + C+
Sbjct: 342 PVPYWEVQPATFRCV 356
>sp|P21809|PGS1_BOVIN BONE/CARTILAGE PROTEOGLYCAN I PRECURSOR (BIGLYCAN) (LEUCINE-RICH PG
I) (PG-S1)
gb|AAB46746.2| (S82652) biglycan core protein precursor [Bos taurus]
Length = 369
Score = 118 bits (294), Expect = 7e-26
Identities = 98/315 (31%), Positives = 150/315 (47%), Gaps = 17/315 (5%)
Query: 22 DYDFPPSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDH 80
D D P Y S C C+C + + C +L LK+VP + P L L+NN I
Sbjct: 52 DLDSLPPTY---SAMCPFGCHC---HLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISE 105
Query: 81 IDEKAFENVTDLQWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLE 140
+ + F+ + L L+L +N + SKI + FS L++L+KL+I+ N+L E LP SL
Sbjct: 106 LRKDDFKGLQHLYALVLVNNKI--SKIHEKAFSPLRKLQKLYISKNHLCEIPPNLPSSLV 163
Query: 141 DLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVS-AAFKGLKSLEYLDLSFNQIA 197
+L++ N+I K+ G F GL N+ I + N L+ AF GLK L YL +S ++
Sbjct: 164 ELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLT 222
Query: 198 RLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLV 257
+P LP +L L+LD+NKI I E R++ L L L HN++ SF + +L
Sbjct: 223 GIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF-LPTLR 281
Query: 258 ELDLSYNKLKNIPT---XXXXXXXXXXXXXXXXKFDIKSFCKILGPLSYSKIKHLRLDGN 314
EL L NKL +P K + FC + + + + L N
Sbjct: 282 ELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNN 341
Query: 315 RISETSLPPDMYECL 329
+ + P + C+
Sbjct: 342 PVPYWEVQPATFACV 356
>sp|O46403|PGS1_HORSE BONE/CARTILAGE PROTEOGLYCAN I PRECURSOR (BIGLYCAN) (PG-S1)
gb|AAB88305.1| (AF035934) biglycan [Equus caballus]
Length = 372
Score = 118 bits (294), Expect = 7e-26
Identities = 94/303 (31%), Positives = 147/303 (48%), Gaps = 14/303 (4%)
Query: 34 SPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDL 92
S C C+C + + C +L LK+VP + P L L+NN+I + + F+ + L
Sbjct: 64 SAMCPFGCHC---HLRVVQCSDLGLKAVPKEISPDTTLLDLQNNEISELRKDDFKGLQHL 120
Query: 93 QWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL 152
L+L +N + SKI + FS L++L+KL+I+ N+L E LP SL +L++ N+I K+
Sbjct: 121 YALVLVNNKI--SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKV 178
Query: 153 --GSFEGLVNLTFIHLQHNRLKEDAVS-AAFKGLKSLEYLDLSFNQIARLPSGLPVSLLT 209
G F GL N+ I + N L+ AF GLK L YL +S ++ +P LP +L
Sbjct: 179 PKGVFSGLRNMNCIEMGGNPLENSGFQPGAFDGLK-LNYLRISEAKLTGIPKDLPETLNE 237
Query: 210 LYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNI 269
L+LD+NKI I E R++ L L L HN++ SF + +L EL L NKL +
Sbjct: 238 LHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF-LPTLRELHLDNNKLSRV 296
Query: 270 PT---XXXXXXXXXXXXXXXXKFDIKSFCKILGPLSYSKIKHLRLDGNRISETSLPPDMY 326
P K + FC + + + + L N + + P +
Sbjct: 297 PAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPYWEVQPATF 356
Query: 327 ECL 329
C+
Sbjct: 357 RCV 359
>ref|NP_058783.1| small proteoglycan I (biglycan), bone (BSPG1) (bone/cartilage
proteclycan 1 precursor) [Rattus norvegicus]
sp|P47853|PGS1_RAT BONE/CARTILAGE PROTEOGLYCAN I PRECURSOR (BIGLYCAN) (PG-S1)
pir||S32793 biglycan precursor - rat
gb|AAA58797.1| (U17834) biglycan [Rattus norvegicus]
Length = 369
Score = 117 bits (291), Expect = 2e-25
Identities = 95/303 (31%), Positives = 146/303 (47%), Gaps = 14/303 (4%)
Query: 34 SPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDL 92
S C C+C + + C +L LK+VP + P L L+NN I + + F+ + L
Sbjct: 61 SAMCPFGCHC---HLRVVQCSDLGLKTVPKEISPDTTLLDLQNNDISELRKDDFKGLQHL 117
Query: 93 QWLILDHNVLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL 152
L+L +N + SKI + FS L++L+KL+I+ N+L E LP SL +L++ N+I K+
Sbjct: 118 YALVLVNNKI--SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKV 175
Query: 153 --GSFEGLVNLTFIHLQHNRLKEDAVS-AAFKGLKSLEYLDLSFNQIARLPSGLPVSLLT 209
G F GL N+ I + N L+ AF GLK L YL +S ++ +P LP +L
Sbjct: 176 PKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPETLNE 234
Query: 210 LYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNI 269
L+LD+NKI I E R++ L L L HN++ SF + +L EL L NKL +
Sbjct: 235 LHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF-LPTLRELHLDNNKLSRV 293
Query: 270 PT---XXXXXXXXXXXXXXXXKFDIKSFCKILGPLSYSKIKHLRLDGNRISETSLPPDMY 326
P K I FC + + + + L N + + P +
Sbjct: 294 PAGLPDLKLLQVVYLHSNNITKVGINDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATF 353
Query: 327 ECL 329
C+
Sbjct: 354 RCV 356
Database: nr
Number of letters in database: 183,345,511
Number of sequences in database: 582,290
Lambda K H
0.318 0.137 0.401
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 120353951
Number of Sequences: 582290
Number of extensions: 4918443
Number of successful extensions: 19853
Number of sequences better than 10.0: 1063
Number of HSP's better than 10.0 without gapping: 281
Number of HSP's successfully gapped in prelim test: 788
Number of HSP's that attempted gapping in prelim test: 12899
Number of HSP's gapped (non-prelim): 3600
length of query: 338
length of database: 183,345,511
effective HSP length: 56
effective length of query: 282
effective length of database: 150,737,271
effective search space: 42507910422
effective search space used: 42507910422
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 71 (32.1 bits)
