Score E
Sequences producing significant alignments: (bits) Value
ref|NP_055674.1| KIAA0672 gene product [Homo sapiens] >gi|3... 1648 0.0
ref|XP_008288.1| KIAA0672 gene product [Homo sapiens] 1645 0.0
pir||T12533 hypothetical protein DKFZp434B034.1 - human (fr... 838 0.0
ref|NP_071580.1| nadrin; neuron-specific GTPase activating ... 656 0.0
dbj|BAB14506.1| (AK023281) unnamed protein product [Homo sa... 552 e-156
ref|NP_061830.1| SH3-domain binding protein 1 [Homo sapiens... 375 e-102
ref|NP_033190.1| SH3-domain binding protein 1 [Mus musculus... 363 5e-99
gb|AAF55715.1| (AE003728) CG4755 gene product [Drosophila m... 242 2e-62
dbj|BAB14683.1| (AK023797) unnamed protein product [Homo sa... 213 4e-54
gb|AAB22808.1| 3BP-1=Bcr/guanosine triphosphatase-activatin... 195 1e-48
gb|AAF59636.1| (AC024755) contains similarity to TR:O75160 ... 171 2e-41
pir||T46916 hypothetical protein DKFZp762E117.1 - human (fr... 165 2e-39
ref|NP_004136.1| myosin IXB [Homo sapiens] >gi|11276964|pir... 111 3e-23
ref|XP_008854.1| myosin IXB [Homo sapiens] 108 2e-22
dbj|BAA96025.1| (AB040934) KIAA1501 protein [Homo sapiens] 106 8e-22
dbj|BAA92662.1| (AB037845) KIAA1424 protein [Homo sapiens] 106 1e-21
gb|AAF80386.1|AF159851_1 (AF159851) Rho GAP p190-A [Homo sa... 105 2e-21
ref|NP_056557.1| myosin IXb [Mus musculus] >gi|6002741|gb|A... 105 2e-21
ref|NP_037116.1| unconventional myosin from rat 3 [Rattus n... 105 2e-21
ref|XP_009038.1| glucocorticoid receptor DNA binding factor... 104 5e-21
gb|AAF49953.1| (AE003542) CG6811 gene product [Drosophila m... 104 5e-21
sp|P34588|YN54_CAEEL HYPOTHETICAL 80.8 KD PROTEIN ZC21.4 IN... 104 5e-21
gb|AAA18934.1| (U02289) GTPase-activating protein [Caenorha... 104 5e-21
pir||S44876 ZC21.4 protein - Caenorhabditis elegans >gi|289... 104 5e-21
gb|AAF53844.1| (AE003664) CdGAPr gene product [Drosophila m... 100 8e-20
gb|AAF44627.1| (AF218776) GTPase activating protein [Drosop... 100 8e-20
ref|XP_010255.1| similar to oligophrenin 1 (H. sapiens) [Ho... 99 1e-19
ref|NP_002538.1| oligophrenin 1, Rho-GTPase acivating prote... 99 1e-19
gb|AAB84002.1| (AF027687) GTPase activating protein homolog... 99 2e-19
gb|AAB82943.1| (AF029913) GTPase activating protein homolog... 99 2e-19
ref|NP_064656.1| Cdc42 GTPase-activating protein [Mus muscu... 99 2e-19
pir||T27959 hypothetical protein ZK669.1b - Caenorhabditis ... 99 2e-19
pir||T27958 hypothetical protein ZK669.1a - Caenorhabditis ... 99 2e-19
ref|XP_007473.1| Rho GTPase activating protein 5 [Homo sapi... 98 3e-19
gb|AAF46047.1| (AE003434) CG3208 gene product [Drosophila m... 98 3e-19
dbj|BAA86518.1| (AB033030) KIAA1204 protein [Homo sapiens] 98 3e-19
dbj|BAA91979.1| (AK001923) unnamed protein product [Homo sa... 98 4e-19
pir||T46354 hypothetical protein DKFZp434F1016.1 - human (f... 98 4e-19
ref|NP_008832.1| myosin IXA [Homo sapiens] >gi|5732618|gb|A... 98 4e-19
ref|NP_033836.1| rho GTPase activating protein 5 [Mus muscu... 98 4e-19
pir||A38218 GAP-associated protein p190 - rat 98 4e-19
pir||T46471 hypothetical protein DKFZp434L0130.1 - human >g... 96 1e-18
pir||T31099 myosin-RhoGAP protein, Myr 7 - rat >gi|3955026|... 96 1e-18
gb|AAF22154.1|AF133093_9 (AF133093) protein with characteri... 96 2e-18
emb|CAA71414.2| (Y10388) Graf protein [Homo sapiens] 96 2e-18
pir||T39954 probable gtpase activating protein homolog - fi... 95 3e-18
pir||T20802 hypothetical protein F12F6.5 - Caenorhabditis e... 95 3e-18
gb|AAB60390.1| (U07000) breakpoint cluster region protein [... 95 3e-18
gb|AAB60389.1| (U07000) breakpoint cluster region protein [... 95 3e-18
ref|XP_009870.1| breakpoint cluster region, isoform 1 [Homo... 95 3e-18
>ref|NP_055674.1| KIAA0672 gene product [Homo sapiens]
dbj|BAA31647.1| (AB014572) KIAA0672 protein [Homo sapiens]
Length = 818
Score = 1648 bits (4220), Expect = 0.0
Identities = 818/818 (100%), Positives = 818/818 (100%)
Query: 1 MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGA 60
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGA
Sbjct: 1 MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGA 60
Query: 61 EADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDV 120
EADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDV
Sbjct: 61 EADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDV 120
Query: 121 IEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGAKADALR 180
IEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGAKADALR
Sbjct: 121 IEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGAKADALR 180
Query: 181 EEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQI 240
EEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQI
Sbjct: 181 EEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQI 240
Query: 241 KAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLK 300
KAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLK
Sbjct: 241 KAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLK 300
Query: 301 KLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKL 360
KLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKL
Sbjct: 301 KLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKL 360
Query: 361 QALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNIT 420
QALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNIT
Sbjct: 361 QALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNIT 420
Query: 421 EMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSPDMDPA 480
EMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSPDMDPA
Sbjct: 421 EMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSPDMDPA 480
Query: 481 DRRQPEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAGRKVSCAP 540
DRRQPEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAGRKVSCAP
Sbjct: 481 DRRQPEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAGRKVSCAP 540
Query: 541 PSMQPPAPPAELAAPLPSPLPEQPLDSPAAPALSPSGLGLQPGPERTSTTKSKELSPGSA 600
PSMQPPAPPAELAAPLPSPLPEQPLDSPAAPALSPSGLGLQPGPERTSTTKSKELSPGSA
Sbjct: 541 PSMQPPAPPAELAAPLPSPLPEQPLDSPAAPALSPSGLGLQPGPERTSTTKSKELSPGSA 600
Query: 601 QKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKLAPIPPKVPF 660
QKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKLAPIPPKVPF
Sbjct: 601 QKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKLAPIPPKVPF 660
Query: 661 GQPGAMADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVFT 720
GQPGAMADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVFT
Sbjct: 661 GQPGAMADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVFT 720
Query: 721 STLSKSRPTPKPRQRPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPGESMSTDLVHFDIP 780
STLSKSRPTPKPRQRPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPGESMSTDLVHFDIP
Sbjct: 721 STLSKSRPTPKPRQRPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPGESMSTDLVHFDIP 780
Query: 781 SIHIELGSTLRLSPLEHMRRHSVTDKRDSEEESESTAL 818
SIHIELGSTLRLSPLEHMRRHSVTDKRDSEEESESTAL
Sbjct: 781 SIHIELGSTLRLSPLEHMRRHSVTDKRDSEEESESTAL 818
>ref|XP_008288.1| KIAA0672 gene product [Homo sapiens]
Length = 818
Score = 1645 bits (4213), Expect = 0.0
Identities = 817/818 (99%), Positives = 817/818 (99%)
Query: 1 MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGA 60
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGA
Sbjct: 1 MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGA 60
Query: 61 EADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDV 120
EADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDV
Sbjct: 61 EADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDV 120
Query: 121 IEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGAKADALR 180
IEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGAKADALR
Sbjct: 121 IEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGAKADALR 180
Query: 181 EEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQI 240
EEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQI
Sbjct: 181 EEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQI 240
Query: 241 KAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLK 300
KAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLK
Sbjct: 241 KAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLK 300
Query: 301 KLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKL 360
KLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKL
Sbjct: 301 KLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKL 360
Query: 361 QALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNIT 420
QALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNIT
Sbjct: 361 QALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNIT 420
Query: 421 EMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSPDMDPA 480
EMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSPDMDPA
Sbjct: 421 EMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSPDMDPA 480
Query: 481 DRRQPEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAGRKVSCAP 540
DRRQPEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAGRKVSCAP
Sbjct: 481 DRRQPEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAGRKVSCAP 540
Query: 541 PSMQPPAPPAELAAPLPSPLPEQPLDSPAAPALSPSGLGLQPGPERTSTTKSKELSPGSA 600
PSMQPPAPPAELAAPLPSPLPEQPLDSPAAPALSPSGLGLQPGPERTSTTKSKELSPGSA
Sbjct: 541 PSMQPPAPPAELAAPLPSPLPEQPLDSPAAPALSPSGLGLQPGPERTSTTKSKELSPGSA 600
Query: 601 QKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKLAPIPPKVPF 660
QKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKLAPIPPKVPF
Sbjct: 601 QKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKLAPIPPKVPF 660
Query: 661 GQPGAMADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVFT 720
GQPGAMADQSAGQ SPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVFT
Sbjct: 661 GQPGAMADQSAGQPSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVFT 720
Query: 721 STLSKSRPTPKPRQRPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPGESMSTDLVHFDIP 780
STLSKSRPTPKPRQRPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPGESMSTDLVHFDIP
Sbjct: 721 STLSKSRPTPKPRQRPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPGESMSTDLVHFDIP 780
Query: 781 SIHIELGSTLRLSPLEHMRRHSVTDKRDSEEESESTAL 818
SIHIELGSTLRLSPLEHMRRHSVTDKRDSEEESESTAL
Sbjct: 781 SIHIELGSTLRLSPLEHMRRHSVTDKRDSEEESESTAL 818
>pir||T12533 hypothetical protein DKFZp434B034.1 - human (fragment)
emb|CAB46376.1| (AL096728) hypothetical protein [Homo sapiens]
Length = 413
Score = 838 bits (2140), Expect = 0.0
Identities = 409/417 (98%), Positives = 409/417 (98%), Gaps = 6/417 (1%)
Query: 356 QDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQA 415
QDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQA
Sbjct: 1 QDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQA 60
Query: 416 EGNITEMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSP 475
EGNITEMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSP
Sbjct: 61 EGNITEMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSP 120
Query: 476 DMDPADRRQPEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAGRK 535
DMDPADRRQPEQARRPLSVATDNMMLEFYKKDG MGV VMDTNWVARRGSSAGRK
Sbjct: 121 DMDPADRRQPEQARRPLSVATDNMMLEFYKKDG------MGVMVMDTNWVARRGSSAGRK 174
Query: 536 VSCAPPSMQPPAPPAELAAPLPSPLPEQPLDSPAAPALSPSGLGLQPGPERTSTTKSKEL 595
VSCAPPSMQPPAPPAELAAPLPSPLPEQPLDSPAAPALSPSGLGLQPGPERTSTTKSKEL
Sbjct: 175 VSCAPPSMQPPAPPAELAAPLPSPLPEQPLDSPAAPALSPSGLGLQPGPERTSTTKSKEL 234
Query: 596 SPGSAQKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKLAPIP 655
SPGSAQKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKLAPIP
Sbjct: 235 SPGSAQKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKLAPIP 294
Query: 656 PKVPFGQPGAMADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLAS 715
PKVPFGQPGAMADQSAGQ SPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLAS
Sbjct: 295 PKVPFGQPGAMADQSAGQPSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLAS 354
Query: 716 PSVFTSTLSKSRPTPKPRQRPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPGESMST 772
PSVFTSTLSKSRPTPKPRQRPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPGESMST
Sbjct: 355 PSVFTSTLSKSRPTPKPRQRPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPGESMST 411
>ref|NP_071580.1| nadrin; neuron-specific GTPase activating protein [Rattus
norvegicus]
dbj|BAB12426.1| (AB042827) Nadrin [Rattus norvegicus]
Length = 780
Score = 656 bits (1674), Expect = 0.0
Identities = 384/842 (45%), Positives = 502/842 (59%), Gaps = 86/842 (10%)
Query: 1 MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGA 60
MKKQFNRM+QLANQTVGRAEKTEVLSEDLLQ+E+RL+ V+ + H +HK+L AC QGQ G
Sbjct: 1 MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLIACFQGQHGT 60
Query: 61 EADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDV 120
+A++R KKLPLT LAQ + E SA L +++LLGKML+ CG+ E++LA EL E+ VE+++
Sbjct: 61 DAERRHKKLPLTALAQNMQEASAQL-EESLLGKMLETCGDAENQLAFELSQHEVFVEKEI 119
Query: 121 IEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGAKADALR 180
++PL+ +AEVEIPNIQKQRK LA+LVLD DS R RW Q KSSG ++ Q +K D L+
Sbjct: 120 MDPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSG--TNFQGLPSKIDTLK 177
Query: 181 EEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQI 240
EEM+EA N+VE C+DQL+ADMY+F+AKE +Y +F TL+E QA+YHRK+L +L+ LP++
Sbjct: 178 EEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKALPEM 237
Query: 241 KAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLK 300
+A Q+ W EKP+FG PLEEHL SGREIA PIEACV +LLE GM+EEGLFR+ ASKLK
Sbjct: 238 RAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLK 297
Query: 301 KLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKL 360
KLKAALDC + E+ +DPHA+AGALKSYLRELPEPLMTF LY+EW Q ++VQ+QDKKL
Sbjct: 298 KLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFSLYEEWTQVASVQDQDKKL 357
Query: 361 QALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNIT 420
Q LW C+KLP N N RYLIKFL+KL++ DVNKMTPSN+AIVLGPNLLW + EG +
Sbjct: 358 QYLWTTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWAKQEGTLA 417
Query: 421 EMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSPDMDPA 480
E+ S+ +V +IEPIIQHADWFFPGE+EFN++ + P+ N+N+SS D D
Sbjct: 418 EIAAATSVHVVAVIEPIIQHADWFFPGEVEFNVSEAF-VPL-ATPNSNHSSHTGNDSDSG 475
Query: 481 DRRQPEQARRPLSVATDNMMLEFYKKDGLRK----------IQSMGVRVMDT--NWVARR 528
+ +RP S+A M + KK+ K + + T N
Sbjct: 476 TL----ERKRPASMAV--MEGDLVKKESPPKPKDSVSAAAPVAGRNSNQITTVPNQAQTG 529
Query: 529 GSSAGRKVSCAPPSMQPPAPPAELAAPLPSPLPEQPLDSPAAPALSPSGLGLQPGPERTS 588
G+S V A + P A P+P P +P + P P G Q P +
Sbjct: 530 GNSHQLSVGTAHSAAGPSPHTLRRAVKKPAPAPPKPGNPP------PGHPGGQSSPGTGT 583
Query: 589 TTKSKELSPGSAQKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVS 648
+ K SP Q+ Q Q Q Q Q +R+ S
Sbjct: 584 SPKPSTRSPSPPQQQQQQQQQ-----------QQQQQQQQQQQQQQQQQQQQTPGMRRCS 632
Query: 649 KKLAPI-----PPKVPFGQPGAMADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGYSLASG 703
L PI PP P QP G+ P PTPP TP+P
Sbjct: 633 SSLPPIQAPNHPPPQPPTQP------RLGEQGP-EPGPTPPQTPTP-------------- 671
Query: 704 QLSPAAAPPL---ASPSVFT---STLSKSRPTPKPRQRPTL-PPPQPPTVNLSASSPQST 756
P+ PP +S S T TL + RP PKPR RP++ PPP PP ++ +
Sbjct: 672 ---PSTPPPAKQNSSQSETTQLHGTLPRPRPVPKPRNRPSVPPPPNPPGTHMGDGGLTPS 728
Query: 757 EAPMLDGMSPGESMSTDLVHFDIPSIHIELGSTLRLSPLEHMRRHSVTDKRDSEEESEST 816
++ S ++ + P IH +L S + + H + D + ++EST
Sbjct: 729 VPTASRIVTDTNSRVSESLRNIFPEIHSDLAS-------KEVPGHILL---DIDNDTEST 778
Query: 817 AL 818
AL
Sbjct: 779 AL 780
>dbj|BAB14506.1| (AK023281) unnamed protein product [Homo sapiens]
Length = 726
Score = 552 bits (1407), Expect = e-156
Identities = 329/733 (44%), Positives = 427/733 (57%), Gaps = 66/733 (9%)
Query: 87 DDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLV 146
+D+LLGKML+ CG+ E++LA EL E+ VE+++++PL+ +AEVEIPNIQKQRK LA+LV
Sbjct: 9 EDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLARLV 68
Query: 147 LDMDSSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRDQLSADMYSFVA 206
LD DS R RW Q KSSG ++ Q +K D L+EEM+EA N+VE C+DQL+ADMY+F+A
Sbjct: 69 LDWDSVRARWNQAHKSSG--TNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMA 126
Query: 207 KEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQIKAQQEAWVEKPSFGKPLEEHLTISGR 266
KE +Y +F TL+E QA+YHRK+L +L+ LP+++A Q+ W EKP+FG PL EHL SGR
Sbjct: 127 KEGEYGKFFVTLLEAQADYHRKALAVLEKTLPEMRAHQDKWAEKPAFGTPLAEHLKRSGR 186
Query: 267 EIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSADPHAIAGA 326
EIA PIEACV +LLE GM+EEGLFR+ ASKLKKLKAALDC + E+ +DPHA+AGA
Sbjct: 187 EIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGA 246
Query: 327 LKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLS 386
LKSYLRELPEPLMTF LY+EW Q ++VQ+QDKKLQ LW C+KLP N N RYLIKFL+
Sbjct: 247 LKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLA 306
Query: 387 KLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQIVGIIEPIIQHADWFFP 446
KL++ DVNKMTPSN+AIVLGPNLLW + EG + EM S+ +V +IEPIIQHADWFFP
Sbjct: 307 KLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATSVHVVAVIEPIIQHADWFFP 366
Query: 447 GEIEFNITGNYGSPVHVNHNANYSSMPSPDMDPADRRQPEQARRPLSVATDNMMLEFYKK 506
E+EFN++ + + N ++ + D +R +RP S+A M + KK
Sbjct: 367 EEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLER------KRPASMAV--MEGDLVKK 418
Query: 507 DGLRKIQ---SMGVRVMDTNWVARRGSSAGRKVSCAPPSMQPPAPPAELAAPLPSPL--- 560
+ K + S V N ++ S + + A P A P P L
Sbjct: 419 ESPPKPKDPVSAAVPAPGRN-NSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRA 477
Query: 561 PEQPLDSPAAPALSPSGLGLQPGPERTSTTKSKELSPGSAQKGSPGSSQGTACAGTQPGA 620
++P +P P P G PG + +S T P S P S TQ
Sbjct: 478 VKKPAPAPPKPGNPPPG---HPGGQSSSGTSQ---HPPSLSPKPPTRSPSPP---TQHTG 528
Query: 621 QPGAQPGASPSPSQPPADQSPHTLRKVSKKLAPI-PPKVPFGQPGAMA-------DQSAG 672
QP QP A S P R+ S L+PI P P QP A S G
Sbjct: 529 QPPGQPSAPSQLSAP---------RRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQG 579
Query: 673 QLSPVSL---------------SPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPS 717
+P++L +PTPPSTP P G P SL + Q P A P
Sbjct: 580 PPNPMALPSEHGLEQPSHTPPQTPTPPSTP-PLGKQNP---SLPAPQTLAGGNPETAQP- 634
Query: 718 VFTSTLSKSRPTPKPRQRPTL-PPPQPPTVNLSASSPQSTEAPMLDGMSPGESMSTDLVH 776
TL + RP PKPR RP++ PPPQPP V+ + S + AP + + H
Sbjct: 635 -HAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDSNSRVSEPH 693
Query: 777 FDI-PSIHIELGS 788
I P +H + S
Sbjct: 694 RSIFPEMHSDSAS 706
>ref|NP_061830.1| SH3-domain binding protein 1 [Homo sapiens]
emb|CAB42896.1| (Z83844) dJ37E16.2 (SH3-domain binding protein 1) [Homo sapiens]
Length = 616
Score = 375 bits (953), Expect = e-102
Identities = 249/653 (38%), Positives = 352/653 (53%), Gaps = 82/653 (12%)
Query: 85 LGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAK 144
L D+ +GK L++ +++LA+ L FE+ +ERDV++PL L+E E+P I K +K L K
Sbjct: 8 LDPDSSMGKALEMSCAIQNQLARILAEFEMTLERDVLQPLSRLSEEELPAILKHKKSLQK 67
Query: 145 LVLDMDSSRTRWQQTSKSSGLSSSLQPAGA---------KADALREEMEEAANRVEICRD 195
LV D ++ ++R Q +K+SG S L + K + L+EE EE +VE CRD
Sbjct: 68 LVSDWNTLKSRLSQATKNSGSSQGLGGSPGSHSHTTMANKVETLKEEEEELKRKVEQCRD 127
Query: 196 QLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQIKAQQEAWVEKPS--- 252
+ AD+Y FV KE YANYF L+E+QA+YHR+SL+ L L +++ PS
Sbjct: 128 EYLADLYHFVTKEDSYANYFIRLLEIQADYHRRSLSSLDTALAELRENHGQADHSPSMTA 187
Query: 253 ------FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEE-GLFRVAPSASKLKKLKAA 305
+G L HL GREIA PIEACV MLL GM+EE GLFR+A AS LK+LK
Sbjct: 188 THFPRVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEVGLFRLAAGASVLKRLKQT 247
Query: 306 LDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWN 365
+ ++E+ +DPHA+AGALKSYLRELPEPLMTF+LYD+W++A++++E +LQAL
Sbjct: 248 MASDPHSLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQE 307
Query: 366 ACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLW-PQAEGNITEM-- 422
C +LP N +N+RYL+KFL++L+E Q+VNKMTPSN+AIVLGPNLLW P+ EG+ ++
Sbjct: 308 VCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDA 367
Query: 423 MTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYG--------SPVHVNHNANYSSMPS 474
+ S+Q+VG++E +IQ AD FPG+I FN++G + S + +++P+
Sbjct: 368 ASVSSIQVVGVVEALIQSADTLFPGDINFNVSGLFSAVTLQDTVSDRLASEELPSTAVPT 427
Query: 475 PDMDPADRRQPEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAGR 534
P PA P A P + S + + V R +S
Sbjct: 428 PATTPAPAPAPAPAPAP-------------------ALASAATKERTESEVPPRPASP-- 466
Query: 535 KVSCAPPSMQPPAPPAELA----APLPSPLPEQPLDSPAAPALSPSGLGLQPGPERTSTT 590
KV+ +PP + AP ++A +P P SP AP L P G T
Sbjct: 467 KVTRSPP--ETAAPVEDMARRTRPTMPPPQVSGSRSSPPAPPLPPGS-----GSPGTPQA 519
Query: 591 KSKELSPGSAQKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQP-PADQSPHTLRKVSK 649
+ L S + +P QP + + ASPSP+ P PA SP +L
Sbjct: 520 LPRRLVGSSLR--APTVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSN--- 574
Query: 650 KLAPIPPKVPFGQPGAMADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGYSLAS 702
P +V G A G +S PTPP+ P P+ SLAS
Sbjct: 575 -----PAQVDLG----AATAEGGAPEAISGVPTPPAIP-----PQPRPRSLAS 613
Score = 44.5 bits (103), Expect = 0.004
Identities = 38/109 (34%), Positives = 53/109 (47%), Gaps = 11/109 (10%)
Query: 666 MADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGY----SLASGQLSPAAAPPL-ASPSVFT 720
++D+ A + P + PTP +TP+P P S A+ + + + PP ASP V
Sbjct: 411 VSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTR 470
Query: 721 STLSKSRPTPKP--RQRPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPG 767
S + P R RPT+PPPQ V+ S SSP + P G SPG
Sbjct: 471 SPPETAAPVEDMARRTRPTMPPPQ---VSGSRSSPPAPPLPPGSG-SPG 515
Score = 41.0 bits (94), Expect = 0.051
Identities = 47/181 (25%), Positives = 69/181 (37%), Gaps = 28/181 (15%)
Query: 569 AAPALSPSGLGLQPGPERTSTTKSKELSPGSAQKGSPGSSQGTACAGTQPGAQPGAQPGA 628
+A L P + ++ T +S A + P ++ T P P P
Sbjct: 385 SADTLFPGDINFNVSGLFSAVTLQDTVSDRLASEELPSTAVPT------PATTPAPAPAP 438
Query: 629 SPSPSQPPADQSPHTLRKVSKKLAPIP--PKVPFGQPGAMADQSAGQLSPVSLSPTPPST 686
+P+P+ PA S T + ++ P P PKV P ++A + ++ T P+
Sbjct: 439 APAPA--PALASAATKERTESEVPPRPASPKVTRSPP-----ETAAPVEDMARR-TRPTM 490
Query: 687 PSPYGLSYPQGYSLASGQLSPAAAPPL--ASPSVFTSTLSKSRPTPKPRQRPTLPPPQPP 744
P P SG S APPL S S T R + PT+PPP PP
Sbjct: 491 PPPQ----------VSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPP 540
Query: 745 T 745
T
Sbjct: 541 T 541
>ref|NP_033190.1| SH3-domain binding protein 1 [Mus musculus]
sp|P55194|3BP1_MOUSE SH3-BINDING PROTEIN 3BP-1
pir||S56144 SH3 domain binding protein - mouse
emb|CAA61011.1| (X87671) SH3 domain binding protein [Mus musculus]
Length = 601
Score = 363 bits (921), Expect = 5e-99
Identities = 226/590 (38%), Positives = 323/590 (54%), Gaps = 41/590 (6%)
Query: 85 LGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAK 144
L D+ +GK L++ +++LA+ L FE+ +ERDV++ L+E E+P I K +K L K
Sbjct: 8 LDPDSSMGKALEMTCAIQNQLARILAEFEMTLERDVLQRSGRLSEEELPAILKHKKSLQK 67
Query: 145 LVLDMDSSRTRWQQTSKSSGLSSSLQPAGA---------KADALREEMEEAANRVEICRD 195
LV D ++ ++R Q +K+SG + L A K + L+EE EE +VE C+D
Sbjct: 68 LVSDWNTLKSRLSQAAKNSGSNQGLGGASGSHTHTTTANKVEMLKEEEEELKKKVEQCKD 127
Query: 196 QLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQIKAQQEAWVEKPS--- 252
+ AD+Y F KE YANYF L+E+QA+YHRKSLT L L +++ P
Sbjct: 128 EYLADLYHFSTKEDSYANYFIHLLEIQADYHRKSLTSLDTALAELRDNHNQADHSPLTTA 187
Query: 253 ------FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEE-GLFRVAPSASKLKKLKAA 305
+G L HL GR+IA PIEACV +LL GMQEE GLFR+A AS LK+LK
Sbjct: 188 APFSRVYGVSLRTHLQDLGRDIALPIEACVLLLLSEGMQEEEGLFRLAAGASVLKRLKQT 247
Query: 306 LDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWN 365
+ ++E+ + PHA+AGALKSYLRELPEPLMT +LYD+W++A++++E +L+AL +
Sbjct: 248 MASDPHSLEEFCSGPHAVAGALKSYLRELPEPLMTSDLYDDWMRAASLKEPGARLEALHD 307
Query: 366 ACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLW-PQAEGNITEM-- 422
C +LP+ N NN+RYL+KFL+ L+E QDVNKMTPSN+AIVLGPNLLW P+ EG+ ++
Sbjct: 308 VCSRLPQENFNNLRYLMKFLALLAEEQDVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDA 367
Query: 423 MTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYG--SPVHVNHNANYSSMPSPDMDPA 480
+ S+Q+VG++E +IQ+AD FPG+I FN++G + +P + S P PA
Sbjct: 368 ASVSSIQVVGVVEALIQNADTLFPGDINFNVSGIFPGLAPQEKVSSQQVSEELPPVTVPA 427
Query: 481 DRRQPEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAGRKVSCAP 540
P P S+A K K+ +T A + ++ + A
Sbjct: 428 PATTPAPTLAPASMAVRERTEADLPKPTSPKVSR---NPTETAASAEDMTRKTKRPAPAR 484
Query: 541 PSMQPPAPPAELAAPLPSPLPEQPLDSPAAPALSPSGL------------GLQPGPERTS 588
P+M PP P + ++P LP + SP P P L L P P + +
Sbjct: 485 PTMPPPQPSSTRSSPPAPSLPPGSV-SPGTPQALPRRLVGTSLRAPTMPPPLPPVPPQPA 543
Query: 589 TTKSKELSPGSAQKGSPGS-SQGTACAGTQPGAQPGAQPGASPSPSQPPA 637
+S+ L P QG A + G P P QPPA
Sbjct: 544 RRQSRRLPASPVISNMPAQVDQGVATEDREGPEAVGGHPPPPALPPQPPA 593
Score = 49.6 bits (116), Expect = 1e-04
Identities = 42/172 (24%), Positives = 67/172 (38%), Gaps = 10/172 (5%)
Query: 548 PPAELAAPLPSPLPEQPLDSPAAPALSPSGLGLQPGPERTSTTKSKELSPGSAQKGSPGS 607
PP + AP +P P +PA+ A+ P P +++ + SA+ + +
Sbjct: 421 PPVTVPAPATTPAPTL---APASMAVRERTEADLPKPTSPKVSRNPTETAASAEDMTRKT 477
Query: 608 SQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKL------AP-IPPKVPF 660
+ T P QP + + P+PS PP SP T + + ++L AP +PP +P
Sbjct: 478 KRPAPARPTMPPPQPSSTRSSPPAPSLPPGSVSPGTPQALPRRLVGTSLRAPTMPPPLPP 537
Query: 661 GQPGAMADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPP 712
P QS + +S P +G G P A PP
Sbjct: 538 VPPQPARRQSRRLPASPVISNMPAQVDQGVATEDREGPEAVGGHPPPPALPP 589
Score = 39.9 bits (91), Expect = 0.11
Identities = 32/121 (26%), Positives = 44/121 (35%), Gaps = 13/121 (10%)
Query: 626 PGASPSPSQPPADQS--PHTLRKVSKKLAPIPPKVPFGQPGAMADQSAGQLSPVSLSPTP 683
P +P+P+ PA + T + K +P + P + D + P PT
Sbjct: 428 PATTPAPTLAPASMAVRERTEADLPKPTSPKVSRNPTETAASAEDMTRKTKRPAPARPTM 487
Query: 684 PSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVFTSTLSKSRPTPKPRQRPTLPPPQP 743
P S P SL G +SP L V TS + PT+PPP P
Sbjct: 488 PPPQPSSTRSSPPAPSLPPGSVSPGTPQALPRRLVGTSL-----------RAPTMPPPLP 536
Query: 744 P 744
P
Sbjct: 537 P 537
Score = 39.1 bits (89), Expect = 0.20
Identities = 36/114 (31%), Positives = 53/114 (45%), Gaps = 17/114 (14%)
Query: 662 QPGAMADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVF-- 719
Q + Q + +L PV++ P P +TP+P S+A + + A P SP V
Sbjct: 408 QEKVSSQQVSEELPPVTV-PAPATTPAPTLAPA----SMAVRERTEADLPKPTSPKVSRN 462
Query: 720 -----TSTLSKSRPTPKPRQ-RPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPG 767
S +R T +P RPT+PPPQP + + SSP + P +SPG
Sbjct: 463 PTETAASAEDMTRKTKRPAPARPTMPPPQPSS---TRSSPPAPSLPP-GSVSPG 512
>gb|AAF55715.1| (AE003728) CG4755 gene product [Drosophila melanogaster]
Length = 740
Score = 242 bits (610), Expect = 2e-62
Identities = 215/792 (27%), Positives = 356/792 (44%), Gaps = 105/792 (13%)
Query: 1 MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGA 60
MK+QF +++ +A + + R+ K++ +L +E++++ + +KL A L G G+
Sbjct: 1 MKRQFAKIK-IAAENLSRSSKSDSKDSELEAIERQVDRYRDTIEKIVRKLPA-LSGGGGS 58
Query: 61 ------EADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFEL 114
E DKR+KK +AQ L E + L D L K+L CGE E +A+ +I EL
Sbjct: 59 GSGSSEEQDKRTKKNSHYKIAQALDESAKELPKDMPLQKVLANCGELEKTMAECIIESEL 118
Query: 115 QVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGA 174
+ E V+ L + + EI I ++++++ + + S + +S + L+ A
Sbjct: 119 ETEAKVVRRLKNILDKEIQEISTLKRNVSRTLQEYTSLK-------RSHEAAIRLEEPAA 171
Query: 175 KADALREEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQ 234
K + ++ + EE ++E RD +A M +AKE + + + + Q YH ++L +
Sbjct: 172 KVNHIKSQQEECELKLEKERDAWAAQMLELIAKEDEIVSCIRDYVLNQRNYHERALQHVN 231
Query: 235 AVLPQIKAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAP 294
A L +I+ + EK FG L+EHLT + REI++ +E C LLE G++EEGL RV
Sbjct: 232 ASLARIQDTIQG-TEKSRFGTSLKEHLTSTNREISYIVELCCCCLLEHGLEEEGLLRVGC 290
Query: 295 SASKLKKLKAALDCCVVDVQ---EYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQAS 351
+++KL+++K AL+ V +Y DPH I LK YLRELPEPL+T+ LY ++I+ +
Sbjct: 291 ASTKLRRMKHALEAQHVKTPLPLDYQ-DPHVIGSILKLYLRELPEPLLTYNLYKDFIRIA 349
Query: 352 NVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLL 411
+ ++ + KLPK N+ N+RYL +FLS + + +NKM+ N+AIV+ PN+L
Sbjct: 350 ERHSEAERKTEIKAILTKLPKENYANLRYLTRFLSIVQQRSALNKMSSQNLAIVMSPNML 409
Query: 412 WPQAEGN-------ITEMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVN 464
WP+ + + I ++ ++ + I I+E +I D+FF GE+EF +T
Sbjct: 410 WPRIDKSSNAPADYIGQVNSSSAANI--IVELLISQWDYFFIGEVEFYLTLQKQKLFVEG 467
Query: 465 HNANYSSMPSPDMDPAD----------RRQPEQARRPLSVATDNMMLEFYKKDGLRKIQS 514
+ + SS + D + ++ RRQ A P + + +
Sbjct: 468 KSKSNSSNENLDRNDSEVMESPRYGTLRRQKANAPSPPTTNGNGI--------------- 512
Query: 515 MGVRVMDTNWVARRGSSAGRKVSCAPPSMQPPA-PPAELAAPLPSPLPEQPLDSPAAPAL 573
+M T+ + R + P + PA PP SP QP + P
Sbjct: 513 ----IMTTSQTSHRPHAKELFPQQTPEKQEKPAKPPLPNLPQFQSPAASQPTQTQLEPLP 568
Query: 574 SPS---------------GLGLQPGP----ERTSTTKSKELSPGSAQKGSPGSSQGTACA 614
P GL P P + T + S +L P QK
Sbjct: 569 PPPVTPAKPVPMTRTQFFGLDNLPSPTADRKSTDSIGSFKLKPDVPQKPLLPKRPTVLGV 628
Query: 615 GTQPGAQPGAQPGASPSPSQPPADQSPHTLR-KVSKKLAPIPPKVPFGQPGAMADQSAGQ 673
G P A + +P+Q D ++R K L + + G+ + S+
Sbjct: 629 GV-PKADGKSDDEGGTTPTQATIDNGNGSVRFKTEHFLDKL--RQENGETNGTREVSS-T 684
Query: 674 LSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVFTSTLSKSRPTPKPR 733
+ + PP+T + A P V T S TPK
Sbjct: 685 TKENNHNHDPPATAADQNQQQ-------------------AQPQVTTPISPNSFQTPK-- 723
Query: 734 QRPTLPPPQPPT 745
RPT+P P PPT
Sbjct: 724 -RPTVPAPPPPT 734
>dbj|BAB14683.1| (AK023797) unnamed protein product [Homo sapiens]
Length = 121
Score = 213 bits (538), Expect = 4e-54
Identities = 105/107 (98%), Positives = 105/107 (98%)
Query: 666 MADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVFTSTLSK 725
MADQSAGQ SPVSLSPT PSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVFTSTLSK
Sbjct: 1 MADQSAGQPSPVSLSPTQPSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVFTSTLSK 60
Query: 726 SRPTPKPRQRPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPGESMST 772
SRPTPKPRQRPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPGESMST
Sbjct: 61 SRPTPKPRQRPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPGESMST 107
>gb|AAB22808.1| 3BP-1=Bcr/guanosine triphosphatase-activating protein-rho homolog
[mice, pre-B cells, Peptide, 339 aa]
Length = 339
Score = 195 bits (491), Expect = 1e-48
Identities = 125/334 (37%), Positives = 179/334 (53%), Gaps = 25/334 (7%)
Query: 321 HAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRY 380
HA+AGALKSYLRELPEPLMT +LYD+W++A++++E +L+AL + C +LP+ N NN+RY
Sbjct: 1 HAVAGALKSYLRELPEPLMTSDLYDDWMRAASLKEPGARLEALHDVCSRLPQENFNNLRY 60
Query: 381 LIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLW-PQAEGNITEM--MTTVSLQIVGIIEPI 437
L+KFL+ L+E QDVNKMTPSN+AIVLGPNLLW P+ EG+ ++ + S+Q+VG++E +
Sbjct: 61 LMKFLALLAEEQDVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEAL 120
Query: 438 IQHADWFFPGEIEFNITGNYG--SPVHVNHNANYSSMPSPDMDPADRRQPEQARRPLSVA 495
IQ+AD FPG+I FN++G + +P + S P PA P P S+A
Sbjct: 121 IQNADTLFPGDINFNVSGIFPGLAPQEKVSSQQVSEELPPVTVPAPATTPAPTLAPASMA 180
Query: 496 TDNMMLEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAGRKVSCAPPSMQPPAPPAELAAP 555
K K+ +T A + ++ + A P+M PP P + ++P
Sbjct: 181 VRERTEADLPKPTSPKVSR---NPTETAASAEDMTRKTKRPAPARPTMPPPQPSSTRSSP 237
Query: 556 LPSPLPEQPLDSPAAPALSPSGL------------GLQPGPERTSTTKSKELSPGSAQKG 603
LP + SP P P L L P P + + +S+ L
Sbjct: 238 PAPSLPPGSV-SPGTPQALPRRLVGTSLRAPTMPPPLPPVPPQPARRQSRRLPASPVISN 296
Query: 604 SPGS-SQGTACAGTQPGAQPGAQPGASPSPSQPP 636
P QG A T+ P A G P P+ PP
Sbjct: 297 MPAQVDQGVA---TEDREGPEAVGGHPPPPALPP 327
Score = 50.8 bits (119), Expect = 6e-05
Identities = 43/176 (24%), Positives = 68/176 (38%), Gaps = 10/176 (5%)
Query: 548 PPAELAAPLPSPLPEQPLDSPAAPALSPSGLGLQPGPERTSTTKSKELSPGSAQKGSPGS 607
PP + AP +P P +PA+ A+ P P +++ + SA+ + +
Sbjct: 159 PPVTVPAPATTPAPTL---APASMAVRERTEADLPKPTSPKVSRNPTETAASAEDMTRKT 215
Query: 608 SQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKL------AP-IPPKVPF 660
+ T P QP + + P+PS PP SP T + + ++L AP +PP +P
Sbjct: 216 KRPAPARPTMPPPQPSSTRSSPPAPSLPPGSVSPGTPQALPRRLVGTSLRAPTMPPPLPP 275
Query: 661 GQPGAMADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLASP 716
P QS + +S P +G G P A PP P
Sbjct: 276 VPPQPARRQSRRLPASPVISNMPAQVDQGVATEDREGPEAVGGHPPPPALPPQPRP 331
Score = 39.9 bits (91), Expect = 0.11
Identities = 32/121 (26%), Positives = 44/121 (35%), Gaps = 13/121 (10%)
Query: 626 PGASPSPSQPPADQS--PHTLRKVSKKLAPIPPKVPFGQPGAMADQSAGQLSPVSLSPTP 683
P +P+P+ PA + T + K +P + P + D + P PT
Sbjct: 166 PATTPAPTLAPASMAVRERTEADLPKPTSPKVSRNPTETAASAEDMTRKTKRPAPARPTM 225
Query: 684 PSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVFTSTLSKSRPTPKPRQRPTLPPPQP 743
P S P SL G +SP L V TS + PT+PPP P
Sbjct: 226 PPPQPSSTRSSPPAPSLPPGSVSPGTPQALPRRLVGTSL-----------RAPTMPPPLP 274
Query: 744 P 744
P
Sbjct: 275 P 275
Score = 39.1 bits (89), Expect = 0.20
Identities = 36/114 (31%), Positives = 53/114 (45%), Gaps = 17/114 (14%)
Query: 662 QPGAMADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAAPPLASPSVF-- 719
Q + Q + +L PV++ P P +TP+P S+A + + A P SP V
Sbjct: 146 QEKVSSQQVSEELPPVTV-PAPATTPAPTLAPA----SMAVRERTEADLPKPTSPKVSRN 200
Query: 720 -----TSTLSKSRPTPKPRQ-RPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPG 767
S +R T +P RPT+PPPQP + + SSP + P +SPG
Sbjct: 201 PTETAASAEDMTRKTKRPAPARPTMPPPQPSS---TRSSPPAPSLPP-GSVSPG 250
>gb|AAF59636.1| (AC024755) contains similarity to TR:O75160 [Caenorhabditis
elegans]
Length = 604
Score = 171 bits (430), Expect = 2e-41
Identities = 113/386 (29%), Positives = 196/386 (50%), Gaps = 28/386 (7%)
Query: 56 GQQGAEADKRSKKLPLTTLAQCLMEGSAILG--DDTLLGKMLKLCGETEDKLAQELIHFE 113
G + DKR KK+ T+AQ L E S L + L +++ G E + E
Sbjct: 55 GFKEENVDKRKKKVEELTMAQNLREASVDLDYFQTSCLHRVINAYGTVLHAEVDEKVKLE 114
Query: 114 LQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAG 173
+ +ER V E L +E E N+ K + L + D++ ++ + K + ++
Sbjct: 115 MAMERRVYEELAPFSEYE-KNVNKLKDKLNLVSTDLEIAQ---KDLEKENSMTH------ 164
Query: 174 AKADALREEMEEAANRVEICRDQLSADMY-SFVAKEIDYANYFQTLIEVQAEYHRKSLTL 232
+E ++ + E +D L D++ S V+KE + T + ++ +Y +K +
Sbjct: 165 ------QESLDAIQMKYEGMKDALVTDIFASSVSKEFQLNEHMLTSMNLKRDYFKKMYEM 218
Query: 233 LQAVLPQIKAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRV 292
+ +P+++ + +P FG PL+EHL+I I+ + C L + GM E G+FRV
Sbjct: 219 YEKAIPEVERMIATALPRPVFGVPLDEHLSIQKERISGVLTKCCDFLRQNGMNERGIFRV 278
Query: 293 APSASKLKKLKAALDCCVVDVQE--YSADPHAIAGALKSYLRELPEPLMTFELYDEWIQA 350
+ +ASK+K+++AALD D E Y+ DPHA+A LK+YLRELP+PL L +W++A
Sbjct: 279 SGNASKIKRIRAALDAGQFDADEKHYNNDPHAVASTLKAYLRELPDPLTMDSLQSDWVEA 338
Query: 351 SNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNL 410
N+ E +++ A+ +K+ + + N+ YL+KFL L ++ M SN+AIV P +
Sbjct: 339 INL-EGEERFSAIDRCLKKMTRGHRQNLIYLMKFLCDLEAKREETSMNASNLAIVFAPTM 397
Query: 411 LWPQAEG------NITEMMTTVSLQI 430
+G +TE M + ++I
Sbjct: 398 TGMIYDGMNTHGVKLTEFMISNGVRI 423
>pir||T46916 hypothetical protein DKFZp762E117.1 - human (fragment)
emb|CAB75671.1| (AL157480) hypothetical protein [Homo sapiens]
Length = 346
Score = 165 bits (414), Expect = 2e-39
Identities = 123/379 (32%), Positives = 183/379 (47%), Gaps = 55/379 (14%)
Query: 339 MTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMT 398
MTF+LYD+W++A++++E +LQAL C +LP N +N+RYL+KFL++L+E Q+VNKMT
Sbjct: 5 MTFDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMT 64
Query: 399 PSNMAIVLGPNLLW-PQAEGNITEM--MTTVSLQIVGIIEPIIQHADWFFPGEIEFNITG 455
PSN+AIVLGPNLLW P+ EG+ ++ + S+Q+VG++E +IQ AD FPG+I FN++G
Sbjct: 65 PSNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFPGDINFNVSG 124
Query: 456 NYG--------SPVHVNHNANYSSMPSPDMDPADRRQPEQARRPLSVATDNMMLEFYKKD 507
+ S + +++P+P PA P A P
Sbjct: 125 LFSAVTLQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAP---------------- 168
Query: 508 GLRKIQSMGVRVMDTNWVARRGSSAGRKVSCAPPSMQPPAPPAELAAPLPSPLPEQPLDS 567
+ S + + V R +S KV+ +PP + AP ++A P P +P
Sbjct: 169 ---ALASAATKERTESEVPPRPASP--KVTRSPP--ETAAPVEDMARRTKRPAPARPTMP 221
Query: 568 P---AAPALSPSGLGLQPGPERTSTTKSKELSPGSAQKGSPGSSQGTACAGTQPGAQPGA 624
P + SP L PG T ++ + +P QP +
Sbjct: 222 PPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSR 281
Query: 625 QPGASPSPSQP-PADQSPHTLRKVSKKLAPIPPKVPFGQPGAMADQSAGQLSPVSLSPTP 683
+ ASPSP+ P PA SP +L P +V G A G +S PTP
Sbjct: 282 RSPASPSPASPGPASPSPVSLSN--------PAQVDLG----AATAEGGAPEAISGVPTP 329
Query: 684 PSTPSPYGLSYPQGYSLAS 702
P+ P P+ SLAS
Sbjct: 330 PAIP-----PQPRPRSLAS 343
Score = 44.1 bits (102), Expect = 0.006
Identities = 47/181 (25%), Positives = 65/181 (34%), Gaps = 22/181 (12%)
Query: 569 AAPALSPSGLGLQPGPERTSTTKSKELSPGSAQKGSPGSSQGTACAGTQPGAQPGAQPGA 628
+A L P + ++ T +S A + P ++ T P P P
Sbjct: 109 SADTLFPGDINFNVSGLFSAVTLQDTVSDRLASEELPSTAVPT------PATTPAPAPAP 162
Query: 629 SPSPSQPPADQSPHTLRKVSKKLAPIP--PKVPFGQPGAMADQSAGQLSPVSLSPTPPST 686
+P+P+ PA S T + ++ P P PKV P A +P P+
Sbjct: 163 APAPA--PALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRTKRPAPARPTM 220
Query: 687 PSPYGLSYPQGYSLASGQLSPAAAPPL--ASPSVFTSTLSKSRPTPKPRQRPTLPPPQPP 744
P P SG S APPL S S T R + PT+PPP PP
Sbjct: 221 PPPQ----------VSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPP 270
Query: 745 T 745
T
Sbjct: 271 T 271
Score = 42.2 bits (97), Expect = 0.023
Identities = 39/115 (33%), Positives = 55/115 (46%), Gaps = 17/115 (14%)
Query: 666 MADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGY----SLASGQLSPAAAPPL-ASPSVFT 720
++D+ A + P + PTP +TP+P P S A+ + + + PP ASP V
Sbjct: 135 VSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTR 194
Query: 721 STLSKSRP-------TPKPRQ-RPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPG 767
S + P T +P RPT+PPPQ V+ S SSP + P G SPG
Sbjct: 195 SPPETAAPVEDMARRTKRPAPARPTMPPPQ---VSGSRSSPPAPPLPPGSG-SPG 245
>ref|NP_004136.1| myosin IXB [Homo sapiens]
pir||A59256 myosin-IXb [similarity] - human
gb|AAC50402.1| (U42391) myosin-IXb [Homo sapiens]
Length = 2022
Score = 111 bits (275), Expect = 3e-23
Identities = 92/328 (28%), Positives = 153/328 (46%), Gaps = 22/328 (6%)
Query: 259 EHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSA 318
+ LT + +E + + G+ EGL+R + +A++ ++L+ AL V+ +
Sbjct: 1703 DSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENF 1762
Query: 319 DPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNI 378
HAI G LK +LRELPEPLMTF Y ++++A + E+ ++L A++ E LP+ANHN++
Sbjct: 1763 PIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSL 1822
Query: 379 RYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLL-WPQAEGNITEMMTTVSLQIVGIIEPI 437
LI L K++ +DVN+M+P +AI+ P LL P +T M L+I +E +
Sbjct: 1823 ERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDV--LKITTCVEML 1880
Query: 438 IQHADWFFP------GEIEFNITGNYGSPVHVNHNANYSSMPSPDMDPADRRQPEQARRP 491
I+ + ++E + + + NAN S A R P
Sbjct: 1881 IKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNANKSPKTREPAGGAGRLLTTSRVSP 1940
Query: 492 LSVATDNMMLEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAGRKVSCAPPSMQPPAPP-- 549
S +T N+ L ++ S +R T AR G + + P+ + PA P
Sbjct: 1941 -SPSTRNLALGSWR--------SAALRTRGTGRPARPGRARALRRRPPRPARESPAQPPR 1991
Query: 550 --AELAAPLPSPLPEQPLDSPAAPALSP 575
+ PSPL P S + ++P
Sbjct: 1992 SRPRVRTETPSPLSSGPPPSRSNTGMAP 2019
>ref|XP_008854.1| myosin IXB [Homo sapiens]
Length = 1713
Score = 108 bits (268), Expect = 2e-22
Identities = 68/196 (34%), Positives = 111/196 (55%), Gaps = 4/196 (2%)
Query: 245 EAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKA 304
E VE FG ++ LT + +E + + G+ EGL+R + +A++ ++L+
Sbjct: 1474 EPGVEPGHFGVCVDS-LTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQ 1532
Query: 305 ALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALW 364
AL V+ + HAI G LK +LRELPEPLMTF Y ++++A + E+ ++L A++
Sbjct: 1533 ALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIY 1592
Query: 365 NACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLL-WPQAEGNITEMM 423
E LP+ANHN++ LI L K++ +DVN+M+P +AI+ P LL P +T M
Sbjct: 1593 AVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMK 1652
Query: 424 TTVSLQIVGIIEPIIQ 439
L+I +E +I+
Sbjct: 1653 DV--LKITTCVEMLIK 1666
>dbj|BAA96025.1| (AB040934) KIAA1501 protein [Homo sapiens]
Length = 735
Score = 106 bits (263), Expect = 8e-22
Identities = 60/201 (29%), Positives = 114/201 (55%), Gaps = 6/201 (2%)
Query: 252 SFGKPLEE-HLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCV 310
+FG LEE + + + AC ++ G++ G++RV + + + L+ L+
Sbjct: 493 AFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGP 552
Query: 311 VDVQ---EYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNAC 367
D+ E D + I+ LKS+ R+LPEPL T + Y+++I+A+ +++ ++++ L
Sbjct: 553 GDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLI 612
Query: 368 EKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVS 427
LP + +++L+ L ++++ + NKM P N+A+V GP L+ +E N+T+M+T +
Sbjct: 613 RDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLV-RTSEDNMTDMVTHMP 671
Query: 428 LQIVGIIEPIIQHADWFFPGE 448
I+E +IQH+DWFF E
Sbjct: 672 -DRYKIVETLIQHSDWFFSDE 691
>dbj|BAA92662.1| (AB037845) KIAA1424 protein [Homo sapiens]
Length = 1286
Score = 106 bits (261), Expect = 1e-21
Identities = 65/218 (29%), Positives = 116/218 (52%), Gaps = 11/218 (5%)
Query: 264 SGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQ---EYSADP 320
+ R I ++ C ++ E G++ G++RV + + + ++ L+ + D+ + D
Sbjct: 485 TNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDL 544
Query: 321 HAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRY 380
+ I+ LKS+ R+LPEPL T + Y ++I+A+ ++ +L+ L LP+ ++ +++
Sbjct: 545 NVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETLKF 604
Query: 381 LIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQIVGIIEPIIQH 440
L L ++E + NKM P N+AIV GP L+ +E N+T M+T + Q I+E +IQH
Sbjct: 605 LSAHLKTVAENSEKNKMEPRNLAIVFGPTLV-RTSEDNMTHMVTHMPDQ-YKIVETLIQH 662
Query: 441 ADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSPDMD 478
DWFF E G V + S P P++D
Sbjct: 663 HDWFFTEE------GAEEPLTTVQEESTVDSQPVPNID 694
>gb|AAF80386.1|AF159851_1 (AF159851) Rho GAP p190-A [Homo sapiens]
Length = 1514
Score = 105 bits (260), Expect = 2e-21
Identities = 76/263 (28%), Positives = 124/263 (46%), Gaps = 15/263 (5%)
Query: 238 PQIKAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSAS 297
P+ + W E FG PL +T + I IE C+ + G+ EG++RV+ + S
Sbjct: 1234 PRPSITKATW-ESNYFGVPLTTVVTPE-KPIPIFIERCIEYIEATGLSTEGIYRVSGNKS 1291
Query: 298 KLKKLKAALDCCV-VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQ 356
+++ L+ D +D+ E + +AGA+KS+ ELP+PL+ + + + ++A + ++
Sbjct: 1292 EIESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDR 1351
Query: 357 DKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAE 416
++KL AL +K PK NH +Y+I L+K+S VN MT N++I P L+ P
Sbjct: 1352 EQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFS 1411
Query: 417 GNITEMMTTVSLQIVGIIEPIIQHADWFF-------PGEIEFNITGNYGSPVHVNHNANY 469
T T + IIE IQ +FF P + S V +
Sbjct: 1412 ---TMDALTATRTYQTIIELFIQQCPFFFYNRPITEPPGARPSSPSAVASTVPFLTSTPV 1468
Query: 470 SSMPSPDMDPADRRQPEQARRPL 492
+S PSP P P+ +PL
Sbjct: 1469 TSQPSPPQSPPP--TPQSPMQPL 1489
>ref|NP_056557.1| myosin IXb [Mus musculus]
gb|AAF00118.1|AF143683_1 (AF143683) unconventional myosin 9bc [Mus musculus]
Length = 1961
Score = 105 bits (259), Expect = 2e-21
Identities = 68/216 (31%), Positives = 117/216 (53%), Gaps = 5/216 (2%)
Query: 226 HRKSLTLLQAVLPQI-KAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGM 284
H+K + +Q+ + + E E FG ++ LT + +E + + G+
Sbjct: 1628 HKKCVHKIQSYCSYTGRRKSELGAEPGHFGVCVDS-LTSDKASVPIVLEKLLEHVEMHGL 1686
Query: 285 QEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELY 344
EGL+R + +A++ ++L+ AL V+ HAI G LK +LRELPEPLMTF Y
Sbjct: 1687 YTEGLYRKSGAANRTRELRQALQTDPAAVKLEDFPIHAITGVLKQWLRELPEPLMTFAQY 1746
Query: 345 DEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAI 404
++++A + E+ ++L A++ + LP+ANH ++ LI L K++ +DVN+M+P +AI
Sbjct: 1747 GDFLRAVELPEKQEQLSAIYAVLDHLPEANHTSLERLIFHLVKVALLEDVNRMSPGALAI 1806
Query: 405 VLGPNLL-WPQAEGNITEMMTTVSLQIVGIIEPIIQ 439
+ P LL P +T M L+I +E +I+
Sbjct: 1807 IFAPCLLRCPDNSDPLTSMKDV--LKITTCVEMLIK 1840
>ref|NP_037116.1| unconventional myosin from rat 3 [Rattus norvegicus]
pir||S54307 myosin heavy chain - rat
emb|CAA54700.1| (X77609) myosin heavy chain [Rattus norvegicus]
Length = 1980
Score = 105 bits (259), Expect = 2e-21
Identities = 68/216 (31%), Positives = 117/216 (53%), Gaps = 5/216 (2%)
Query: 226 HRKSLTLLQAVLPQI-KAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGM 284
H+K + +Q+ + + E E FG ++ LT + +E + + G+
Sbjct: 1630 HKKCVHKIQSYCSYTGRRKSELGAEPGHFGVCVDS-LTSDKASVPIVLEKLLEHVEMHGL 1688
Query: 285 QEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELY 344
EGL+R + +A++ ++L+ AL V+ HAI G LK +LRELPEPLMTF Y
Sbjct: 1689 YTEGLYRKSGAANRTRELRQALQTDPATVKLEDFPIHAITGVLKQWLRELPEPLMTFAQY 1748
Query: 345 DEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAI 404
++++A + E+ ++L A++ + LP+ANH ++ LI L K++ +DVN+M+P +AI
Sbjct: 1749 GDFLRAVELPEKQEQLAAIYAVLDHLPEANHTSLERLIFHLVKVALLEDVNRMSPGALAI 1808
Query: 405 VLGPNLL-WPQAEGNITEMMTTVSLQIVGIIEPIIQ 439
+ P LL P +T M L+I +E +I+
Sbjct: 1809 IFAPCLLRCPDNSDPLTSMKDV--LKITTCVEMLIK 1842
>ref|XP_009038.1| glucocorticoid receptor DNA binding factor 1 [Homo sapiens]
Length = 1074
Score = 104 bits (256), Expect = 5e-21
Identities = 65/209 (31%), Positives = 108/209 (51%), Gaps = 6/209 (2%)
Query: 238 PQIKAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSAS 297
P+ + W E FG PL +T + I IE C+ + G+ EG++RV+ + S
Sbjct: 857 PRPSITKATW-ESNYFGVPLTTVVTPE-KPIPIFIERCIEYIEATGLSTEGIYRVSGNKS 914
Query: 298 KLKKLKAALDCCV-VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQ 356
+++ L+ D +D+ E + +AGA+KS+ ELP+PL+ + + + ++A + ++
Sbjct: 915 EMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDR 974
Query: 357 DKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAE 416
++KL AL +K PK NH +Y+I L+K+S VN MT N++I P L+ P
Sbjct: 975 EQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFS 1034
Query: 417 GNITEMMTTVSLQIVGIIEPIIQHADWFF 445
T T + IIE IQ +FF
Sbjct: 1035 ---TMDALTATRTYQTIIELFIQQCPFFF 1060
>gb|AAF49953.1| (AE003542) CG6811 gene product [Drosophila melanogaster]
Length = 476
Score = 104 bits (256), Expect = 5e-21
Identities = 64/190 (33%), Positives = 106/190 (55%), Gaps = 4/190 (2%)
Query: 241 KAQQEAWVEKPSFGKPLEEHLTISGREIAFP--IEACVTMLLECGMQE-EGLFRVAPSAS 297
+ QQ FG PL+ + S + P + CV L G+ + EG+FR + + S
Sbjct: 262 RQQQHKMATTHQFGVPLKFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHS 321
Query: 298 KLKKLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQD 357
++ LK ++ DV S + H IAG LKS+LR+L EPL+TFELY++ + +++
Sbjct: 322 EIMALKERVNRGE-DVDLKSVNVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEE 380
Query: 358 KKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEG 417
+ EKLP+ N+ +Y+++FL ++ + +D+NKMT SN+AIV GPN LW ++
Sbjct: 381 RSRNVTQLIREKLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSRSTS 440
Query: 418 NITEMMTTVS 427
E + ++
Sbjct: 441 TSLEEIAPIN 450
>sp|P34588|YN54_CAEEL HYPOTHETICAL 80.8 KD PROTEIN ZC21.4 IN CHROMOSOME III
Length = 747
Score = 104 bits (256), Expect = 5e-21
Identities = 59/183 (32%), Positives = 106/183 (57%), Gaps = 11/183 (6%)
Query: 272 IEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSA---------DPHA 322
++ACV ++ GM G++R+ + + + LK +L D + S D +
Sbjct: 108 VQACVCVIETYGMDTVGIYRIPGNTAAVNALKESLSNRGFDSVDLSKVESLDPRWRDVNV 167
Query: 323 IAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLI 382
++ LK +LR+LPEPL+T +LY +I A+ + +L L N KLP+ +++ +R+LI
Sbjct: 168 VSSLLKMFLRKLPEPLLTDKLYPFFIDANRISTHHNRLHKLRNLLRKLPRPHYDTLRFLI 227
Query: 383 KFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQIVGIIEPIIQHAD 442
LS+++++ DVNKM N+A++ GP+++ P ++ N+ M+T +S Q IIE +I +
Sbjct: 228 VHLSEITKHSDVNKMECRNLALMFGPSIVRP-SDDNMATMVTHMSDQ-CKIIETLIHYNL 285
Query: 443 WFF 445
W F
Sbjct: 286 WMF 288
>gb|AAA18934.1| (U02289) GTPase-activating protein [Caenorhabditis elegans]
Length = 1439
Score = 104 bits (256), Expect = 5e-21
Identities = 59/183 (32%), Positives = 106/183 (57%), Gaps = 11/183 (6%)
Query: 272 IEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSA---------DPHA 322
++ACV ++ GM G++R+ + + + LK +L D + S D +
Sbjct: 800 VQACVCVIETYGMDTVGIYRIPGNTAAVNALKESLSNRGFDSVDLSKVESLDPRWRDVNV 859
Query: 323 IAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLI 382
++ LK +LR+LPEPL+T +LY +I A+ + +L L N KLP+ +++ +R+LI
Sbjct: 860 VSSLLKMFLRKLPEPLLTDKLYPFFIDANRISTHHNRLHKLRNLLRKLPRPHYDTLRFLI 919
Query: 383 KFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQIVGIIEPIIQHAD 442
LS+++++ DVNKM N+A++ GP+++ P ++ N+ M+T +S Q IIE +I +
Sbjct: 920 VHLSEITKHSDVNKMECRNLALMFGPSIVRP-SDDNMATMVTHMSDQ-CKIIETLIHYNL 977
Query: 443 WFF 445
W F
Sbjct: 978 WMF 980
>pir||S44876 ZC21.4 protein - Caenorhabditis elegans
gb|AAA28171.1| (L16685) homology with breakpoint cluster region protein; putative
[Caenorhabditis elegans]
Length = 733
Score = 104 bits (256), Expect = 5e-21
Identities = 59/183 (32%), Positives = 106/183 (57%), Gaps = 11/183 (6%)
Query: 272 IEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSA---------DPHA 322
++ACV ++ GM G++R+ + + + LK +L D + S D +
Sbjct: 94 VQACVCVIETYGMDTVGIYRIPGNTAAVNALKESLSNRGFDSVDLSKVESLDPRWRDVNV 153
Query: 323 IAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLI 382
++ LK +LR+LPEPL+T +LY +I A+ + +L L N KLP+ +++ +R+LI
Sbjct: 154 VSSLLKMFLRKLPEPLLTDKLYPFFIDANRISTHHNRLHKLRNLLRKLPRPHYDTLRFLI 213
Query: 383 KFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQIVGIIEPIIQHAD 442
LS+++++ DVNKM N+A++ GP+++ P ++ N+ M+T +S Q IIE +I +
Sbjct: 214 VHLSEITKHSDVNKMECRNLALMFGPSIVRP-SDDNMATMVTHMSDQ-CKIIETLIHYNL 271
Query: 443 WFF 445
W F
Sbjct: 272 WMF 274
>gb|AAF53844.1| (AE003664) CdGAPr gene product [Drosophila melanogaster]
Length = 1817
Score = 100 bits (246), Expect = 8e-20
Identities = 66/199 (33%), Positives = 109/199 (54%), Gaps = 8/199 (4%)
Query: 253 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDC-CVV 311
F L EHL SG++I + +C + G+ + G++R++ S +++L+ A D V
Sbjct: 422 FNCDLSEHLLNSGQDIPMVLRSCAEFIENYGVID-GIYRLSGITSNIQRLRRAFDEERVP 480
Query: 312 DV--QEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQ--EQDKKLQALWNAC 367
D+ E D HA++ LK Y RELP PL T++LYD +++A V+ E D++L+ +
Sbjct: 481 DLGNPEMKQDIHAVSSLLKMYFRELPNPLCTYQLYDNFVEAIQVKADEADERLRLMKETV 540
Query: 368 EKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLL-WPQAEGNITEMMTTV 426
KLP ++ ++YL + L K+S++ MT N+AIV PNLL P E + V
Sbjct: 541 LKLPPPHYRTLKYLAEHLYKVSQHHGRTGMTDKNLAIVWAPNLLRSPALESGGVAALRGV 600
Query: 427 SLQIVGIIEPIIQHADWFF 445
+Q V + E +I++ F
Sbjct: 601 GVQAV-VTEYLIRNCHNIF 618
>gb|AAF44627.1| (AF218776) GTPase activating protein [Drosophila melanogaster]
Length = 1843
Score = 100 bits (246), Expect = 8e-20
Identities = 66/199 (33%), Positives = 109/199 (54%), Gaps = 8/199 (4%)
Query: 253 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDC-CVV 311
F L EHL SG++I + +C + G+ + G++R++ S +++L+ A D V
Sbjct: 422 FNCDLSEHLLNSGQDIPMVLRSCAEFIENYGVID-GIYRLSGITSNIQRLRRAFDEERVP 480
Query: 312 DV--QEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQ--EQDKKLQALWNAC 367
D+ E D HA++ LK Y RELP PL T++LYD +++A V+ E D++L+ +
Sbjct: 481 DLGNPEMKQDIHAVSSLLKMYFRELPNPLCTYQLYDNFVEAIQVKADEADERLRLMKETV 540
Query: 368 EKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLL-WPQAEGNITEMMTTV 426
KLP ++ ++YL + L K+S++ MT N+AIV PNLL P E + V
Sbjct: 541 LKLPPPHYRTLKYLAEHLYKVSQHHGRTGMTDKNLAIVWAPNLLRSPALESGGVAALRGV 600
Query: 427 SLQIVGIIEPIIQHADWFF 445
+Q V + E +I++ F
Sbjct: 601 GVQAV-VTEYLIRNCHNIF 618
>ref|XP_010255.1| similar to oligophrenin 1 (H. sapiens) [Homo sapiens]
Length = 643
Score = 99.5 bits (244), Expect = 1e-19
Identities = 64/220 (29%), Positives = 113/220 (51%), Gaps = 13/220 (5%)
Query: 241 KAQQEAWVE-----KPSFGKPLEEHLTISGREIAFP-IEACVTMLLECGMQEEGLFRVAP 294
+A + W+E +P + P+ + + E+ F + C+ ++ G++ EGL+R
Sbjct: 194 EANRRLWMEAMDGKEPIYHSPITKQQEMELNEVGFKFVRKCINIIETKGIKTEGLYRTVG 253
Query: 295 SASKLKKLKAAL--DCCVVDVQEYSAD--PHAIAGALKSYLRELPEPLMTFELYDEWIQA 350
S +++KL A C DV +++D I +LK YLR L EP+MT+ L+ E + A
Sbjct: 254 SNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELVSA 313
Query: 351 SNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNL 410
+ D +L A+ + KLP+ N + LI+ L + E+ N MTPSNM ++ GP L
Sbjct: 314 AKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTL 373
Query: 411 LWPQAEGNITEMMTTVSLQIVGIIEPIIQHADWFFPGEIE 450
+ +A+ + M + Q + ++E +I+H + G E
Sbjct: 374 M--RAQEDTVAAMMNIKFQNI-VVEILIEHFGKIYLGPPE 410
>ref|NP_002538.1| oligophrenin 1, Rho-GTPase acivating protein [Homo sapiens]
emb|CAA04579.1| (AJ001189) oligophrenin 1 [Homo sapiens]
emb|CAB96181.1| (AJ248245) oligophrenin-1 [Homo sapiens]
Length = 802
Score = 99.5 bits (244), Expect = 1e-19
Identities = 64/220 (29%), Positives = 113/220 (51%), Gaps = 13/220 (5%)
Query: 241 KAQQEAWVE-----KPSFGKPLEEHLTISGREIAFP-IEACVTMLLECGMQEEGLFRVAP 294
+A + W+E +P + P+ + + E+ F + C+ ++ G++ EGL+R
Sbjct: 353 EANRRLWMEAMDGKEPIYHSPITKQQEMELNEVGFKFVRKCINIIETKGIKTEGLYRTVG 412
Query: 295 SASKLKKLKAAL--DCCVVDVQEYSAD--PHAIAGALKSYLRELPEPLMTFELYDEWIQA 350
S +++KL A C DV +++D I +LK YLR L EP+MT+ L+ E + A
Sbjct: 413 SNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELVSA 472
Query: 351 SNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNL 410
+ D +L A+ + KLP+ N + LI+ L + E+ N MTPSNM ++ GP L
Sbjct: 473 AKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTL 532
Query: 411 LWPQAEGNITEMMTTVSLQIVGIIEPIIQHADWFFPGEIE 450
+ +A+ + M + Q + ++E +I+H + G E
Sbjct: 533 M--RAQEDTVAAMMNIKFQNI-VVEILIEHFGKIYLGPPE 569
>gb|AAB84002.1| (AF027687) GTPase activating protein homolog [Cochliobolus
heterostrophus]
Length = 714
Score = 99.1 bits (243), Expect = 2e-19
Identities = 50/192 (26%), Positives = 104/192 (54%), Gaps = 6/192 (3%)
Query: 251 PSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCV 310
P FG LEE G + + C+ + G++ EG++R+ ++S ++++KA D
Sbjct: 527 PIFGVTLEELFRRDGSPVPIIVYQCIQAVDLYGLEVEGIYRIPGTSSHIQQMKALFDS-- 584
Query: 311 VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL 370
+ + D +++AG LK + RELP+PL+T E Y ++I+A+ + + + ++ L
Sbjct: 585 ---ESFQHDVNSVAGLLKQFFRELPDPLLTREFYGKYIEAARIDDDTMRRDSMHALINAL 641
Query: 371 PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQI 430
P N+ +R L L ++ + ++N+M+ +N+AI P+++ P N+ + + I
Sbjct: 642 PDPNYATLRALALHLHRVQQSSEINRMSTANLAICWAPSIMGPHKGNNMADAGLQARV-I 700
Query: 431 VGIIEPIIQHAD 442
+ I++ ++Q D
Sbjct: 701 ITILDNVLQIFD 712
>gb|AAB82943.1| (AF029913) GTPase activating protein homolog [Cochliobolus
heterostrophus]
Length = 714
Score = 99.1 bits (243), Expect = 2e-19
Identities = 50/192 (26%), Positives = 104/192 (54%), Gaps = 6/192 (3%)
Query: 251 PSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCV 310
P FG LEE G + + C+ + G++ EG++R+ ++S ++++KA D
Sbjct: 527 PIFGVTLEELFRRDGSPVPIIVYQCIQAVDLYGLEVEGIYRIPGTSSHIQQMKALFDS-- 584
Query: 311 VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKL 370
+ + D +++AG LK + RELP+PL+T E Y ++I+A+ + + + ++ L
Sbjct: 585 ---ESFQHDVNSVAGLLKQFFRELPDPLLTREFYGKYIEAARIDDDTMRRDSMHALINAL 641
Query: 371 PKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQI 430
P N+ +R L L ++ + ++N+M+ +N+AI P+++ P N+ + + I
Sbjct: 642 PDPNYATLRALALHLHRVQQSSEINRMSTANLAICWAPSIMGPHKGNNMADAGLQARV-I 700
Query: 431 VGIIEPIIQHAD 442
+ I++ ++Q D
Sbjct: 701 ITILDNVLQIFD 712
>ref|NP_064656.1| Cdc42 GTPase-activating protein [Mus musculus]
gb|AAD38043.1|AF151363_1 (AF151363) Cdc42 GTPase-activating protein [Mus musculus]
Length = 820
Score = 98.7 bits (242), Expect = 2e-19
Identities = 125/551 (22%), Positives = 224/551 (39%), Gaps = 85/551 (15%)
Query: 252 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAAL---DC 308
+FG L E+L SG+++ + +++C + G+ + G++R++ S +++L+ C
Sbjct: 18 AFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVD-GIYRLSGITSNIQRLRQEFGSDQC 76
Query: 309 CVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACE 368
+ + Y D H + K Y RELP PL+T+ELY+++ +A + + ++ +L + N
Sbjct: 77 PDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHRPEEGQLARIQNVIL 136
Query: 369 KLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLL-WPQAEGNITE---MMT 424
+LP ++ + YLI+ L+ ++ + M N+A+V PNLL + E I
Sbjct: 137 ELPPPHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKKIEATICNGDAAFL 196
Query: 425 TVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSPDMD------ 478
V +Q V +IE I+ HAD F G + + + + S+P +
Sbjct: 197 AVRVQQV-VIEFILNHADQIFNGGAPGALQQDESRTITKSLTLPALSLPMKLVSLEEAQA 255
Query: 479 -------PADRRQPEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTNWVARRGSS 531
PA + + E + + + +LE D RK+ S + + R GS
Sbjct: 256 RSLATNHPARKERRENSLPEIVPPPFHTVLEL--PDNKRKLSSKSKKWKSIFNLGRSGSD 313
Query: 532 AGRKVSCAPPSMQPPAPPAELAAPLPSPLPEQPLDSPAAPALSPSGLGLQPGPERTSTTK 591
+ K+S + L+ + P + +DS ++ G + RT TT
Sbjct: 314 SKSKLS---RNGSVFVRGQRLSVEKATIRPAKSMDSLC--SVPVEGKENKGNFSRTVTTG 368
Query: 592 SKELSPGSAQKGSPGSSQGTACAGT--QPGAQPGAQPGASPSPSQPPADQSPHTLRKVSK 649
+ S GSS + G Q G GA+ G +V
Sbjct: 369 GFFIPATKMHASSTGSSCDLSKEGEWGQEGMPAGAEGGC-----------------EVGG 411
Query: 650 KLAPIPPKVPFGQPGAMADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAA 709
++ P+P ++ +P + D + Q +P L S+ SP
Sbjct: 412 QIRPLPEQLKVFRP--IGDPESEQSAPKLLGMFYTSSDSP-------------------- 449
Query: 710 APPLASPSVFTSTLSKSRPTPKPRQRPTLPPPQPPTVNL---------SASSPQSTEAPM 760
SVFTS+L + P+P+ QR L +P V++ + S+P T
Sbjct: 450 -----GKSVFTSSLFQMEPSPR-HQRKALNISEPFAVSVPLRVSAVISTNSTPCRTPPKE 503
Query: 761 LDGMSPGESMS 771
L +S E S
Sbjct: 504 LQSLSSLEEFS 514
>pir||T27959 hypothetical protein ZK669.1b - Caenorhabditis elegans
emb|CAA85469.1| (Z37093) alternative splicing in ZK669.1a, contains similarity to
Pfam domain: PF00620 (RhoGAP domain), Score=149.9,
E-value=1.5e-41, N=1~cDNA EST yk36g1.5 comes from this
gene [Caenorhabditis elegans]
emb|CAA86848.1| (Z46812) alternative splicing in ZK669.1a, contains similarity to
Pfam domain: PF00620 (RhoGAP domain), Score=149.9,
E-value=1.5e-41, N=1~cDNA EST yk36g1.5 comes from this
gene [Caenorhabditis elegans]
Length = 634
Score = 98.7 bits (242), Expect = 2e-19
Identities = 60/212 (28%), Positives = 114/212 (53%), Gaps = 17/212 (8%)
Query: 214 YFQTLIEVQAEYHRKSLTLLQAVLPQIKAQQEAWVEKPS--FGKPLEEHLTISGREIAFP 271
Y I+ ++H+ +Q Q+ Q V++ + FG PL+ L R I
Sbjct: 140 YTVQCIDCGGQWHKACFPRIQ----QVCGQAAKLVDRRTSIFGVPLKGLLEHQNRHIPLI 195
Query: 272 IEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEY--SADPHAIAGALKS 329
IE + L G++ +G++R SK++++ A + D + + +P +A +K
Sbjct: 196 IEKSIDQLQRRGLRAKGIYRTCGVKSKIEEICNAFERSSSDDEVCLDNENPMNLASVVKL 255
Query: 330 YLRELPEPLMTFELYDEWI---------QASNVQEQDKKLQALWNACEKLPKANHNNIRY 380
YLR+LPEPL+TFELYD+++ QAS ++++++ L KLP N+ +++
Sbjct: 256 YLRKLPEPLLTFELYDDFVRLGTECCSAQASGSNCEEERVEQLRQLARKLPVHNYETLKF 315
Query: 381 LIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLW 412
++ L+++S + +VN M+ SN++ V+ P+L+W
Sbjct: 316 IMLHLNRVSWFHEVNLMSTSNLSTVIAPSLIW 347
>pir||T27958 hypothetical protein ZK669.1a - Caenorhabditis elegans
emb|CAA85468.1| (Z37093) alternative splicing in ZK669.1b, contains similarity to
Pfam domain: PF00620 (RhoGAP domain), Score=149.9,
E-value=1.5e-41, N=1~cDNA EST yk39b7.5 comes from this
gene~cDNA EST yk50c2.5 comes from this gene~cDNA EST
yk39b7.3 comes from this ge>
emb|CAA86847.1| (Z46812) alternative splicing in ZK669.1b, contains similarity to
Pfam domain: PF00620 (RhoGAP domain), Score=149.9,
E-value=1.5e-41, N=1~cDNA EST yk39b7.5 comes from this
gene~cDNA EST yk50c2.5 comes from this gene~cDNA EST
yk39b7.3 comes from this ge>
Length = 863
Score = 98.7 bits (242), Expect = 2e-19
Identities = 60/212 (28%), Positives = 114/212 (53%), Gaps = 17/212 (8%)
Query: 214 YFQTLIEVQAEYHRKSLTLLQAVLPQIKAQQEAWVEKPS--FGKPLEEHLTISGREIAFP 271
Y I+ ++H+ +Q Q+ Q V++ + FG PL+ L R I
Sbjct: 369 YTVQCIDCGGQWHKACFPRIQ----QVCGQAAKLVDRRTSIFGVPLKGLLEHQNRHIPLI 424
Query: 272 IEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEY--SADPHAIAGALKS 329
IE + L G++ +G++R SK++++ A + D + + +P +A +K
Sbjct: 425 IEKSIDQLQRRGLRAKGIYRTCGVKSKIEEICNAFERSSSDDEVCLDNENPMNLASVVKL 484
Query: 330 YLRELPEPLMTFELYDEWI---------QASNVQEQDKKLQALWNACEKLPKANHNNIRY 380
YLR+LPEPL+TFELYD+++ QAS ++++++ L KLP N+ +++
Sbjct: 485 YLRKLPEPLLTFELYDDFVRLGTECCSAQASGSNCEEERVEQLRQLARKLPVHNYETLKF 544
Query: 381 LIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLW 412
++ L+++S + +VN M+ SN++ V+ P+L+W
Sbjct: 545 IMLHLNRVSWFHEVNLMSTSNLSTVIAPSLIW 576
>ref|XP_007473.1| Rho GTPase activating protein 5 [Homo sapiens]
Length = 1500
Score = 98.3 bits (241), Expect = 3e-19
Identities = 61/206 (29%), Positives = 111/206 (53%), Gaps = 12/206 (5%)
Query: 249 EKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDC 308
E FG PL++ +T + I +E CV + + G+ EGL+RV+ + + ++
Sbjct: 1254 ESNYFGMPLQDLVTAE-KPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQF-- 1310
Query: 309 CVVD----VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALW 364
VVD + +A+AGALK++ +LP+PL+ + L+ E ++A+ + ++ ++L AL
Sbjct: 1311 -VVDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALK 1369
Query: 365 NACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMT 424
+K N++ RY+I L+++S+ +N MT N++I P L+ P E E ++
Sbjct: 1370 EIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENR--EFLS 1427
Query: 425 TVSLQIVGIIEPIIQHADWFF-PGEI 449
T + ++E IQ +FF GEI
Sbjct: 1428 TTKIH-QSVVETFIQQCQFFFYNGEI 1452
>gb|AAF46047.1| (AE003434) CG3208 gene product [Drosophila melanogaster]
Length = 494
Score = 98.3 bits (241), Expect = 3e-19
Identities = 58/165 (35%), Positives = 97/165 (58%), Gaps = 4/165 (2%)
Query: 267 EIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCC--VVDVQEYS-ADPHAI 323
+I F + CV + GM +EG++RV+ A +++ LK ALD D+ E + + + I
Sbjct: 317 QIPFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDREGEKTDMSETAYGNVNVI 376
Query: 324 AGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIK 383
AG LK YLR LP PL+TF+ Y ++ A +Q ++ Q + A +LP A+H+ ++Y+++
Sbjct: 377 AGTLKLYLRLLPVPLITFQAYPSFMAAGRTGKQAEQRQLMAEAVRRLPPAHHSCLQYMLE 436
Query: 384 FLSKLSEYQDVNKMTPSNMAIVLGPNLL-WPQAEGNITEMMTTVS 427
L +++ + VNKM N+A V P L+ PQ N+TE + +S
Sbjct: 437 HLKRVASHYAVNKMNEHNLATVFAPTLIATPQHMTNLTEEIFMLS 481
>dbj|BAA86518.1| (AB033030) KIAA1204 protein [Homo sapiens]
Length = 1445
Score = 98.3 bits (241), Expect = 3e-19
Identities = 61/210 (29%), Positives = 113/210 (53%), Gaps = 13/210 (6%)
Query: 252 SFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAAL---DC 308
+FG L E+L SG+++ + +++C + G+ + G++R++ S +++L+ C
Sbjct: 19 AFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVD-GIYRLSGVTSNIQRLRQEFGSDQC 77
Query: 309 CVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACE 368
+ + Y D H + K Y RELP PL+T+ELY+++ +A + ++ +L + N +
Sbjct: 78 PDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLARIQNVIQ 137
Query: 369 KLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP---QAEG-NITEMMT 424
+LP +++ + YLI+ L+ ++ + M N+A+V PNLL +A G N
Sbjct: 138 ELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKEIEATGCNGDAAFL 197
Query: 425 TVSLQIVGIIEPIIQHADWFF----PGEIE 450
V +Q V +IE I+ H D F PG +E
Sbjct: 198 AVRVQQV-VIEFILNHVDQIFNNGAPGSLE 226
>dbj|BAA91979.1| (AK001923) unnamed protein product [Homo sapiens]
Length = 526
Score = 97.9 bits (240), Expect = 4e-19
Identities = 51/159 (32%), Positives = 92/159 (57%), Gaps = 1/159 (0%)
Query: 253 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 312
FG L LT R + +E + + G+ EG++R + S +K+K+L+ LD
Sbjct: 39 FGVELSR-LTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAES 97
Query: 313 VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPK 372
V + H IA K +LR+LP PLMTFELY+E+++A +QE+ + ++ +++ ++L +
Sbjct: 98 VNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSR 157
Query: 373 ANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLL 411
+ N + LI L +++ +D N+M+ + +AIV P +L
Sbjct: 158 THLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCIL 196
>pir||T46354 hypothetical protein DKFZp434F1016.1 - human (fragment)
emb|CAB70679.1| (AL137287) hypothetical protein [Homo sapiens]
Length = 1397
Score = 97.9 bits (240), Expect = 4e-19
Identities = 51/159 (32%), Positives = 92/159 (57%), Gaps = 1/159 (0%)
Query: 253 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 312
FG L LT R + +E + + G+ EG++R + S +K+K+L+ LD
Sbjct: 910 FGVELSR-LTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAES 968
Query: 313 VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPK 372
V + H IA K +LR+LP PLMTFELY+E+++A +QE+ + ++ +++ ++L +
Sbjct: 969 VNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSR 1028
Query: 373 ANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLL 411
+ N + LI L +++ +D N+M+ + +AIV P +L
Sbjct: 1029 THLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCIL 1067
>ref|NP_008832.1| myosin IXA [Homo sapiens]
gb|AAD49195.1|AF117888_1 (AF117888) myosin-IXa [Homo sapiens]
Length = 2548
Score = 97.9 bits (240), Expect = 4e-19
Identities = 51/159 (32%), Positives = 92/159 (57%), Gaps = 1/159 (0%)
Query: 253 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 312
FG L LT R + +E + + G+ EG++R + S +K+K+L+ LD
Sbjct: 2061 FGVELSR-LTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAES 2119
Query: 313 VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPK 372
V + H IA K +LR+LP PLMTFELY+E+++A +QE+ + ++ +++ ++L +
Sbjct: 2120 VNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSR 2179
Query: 373 ANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLL 411
+ N + LI L +++ +D N+M+ + +AIV P +L
Sbjct: 2180 THLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCIL 2218
>ref|NP_033836.1| rho GTPase activating protein 5 [Mus musculus]
pir||T42724 p190-B protein - mouse
gb|AAD12768.1| (U67160) p190-B [Mus musculus]
Length = 1501
Score = 97.9 bits (240), Expect = 4e-19
Identities = 58/203 (28%), Positives = 110/203 (53%), Gaps = 6/203 (2%)
Query: 249 EKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDC 308
E FG PL++ +T + I +E CV + + G+ EGL+RV+ + + ++ D
Sbjct: 1255 ESNYFGMPLQDLVTAE-KPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQ 1313
Query: 309 CV-VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNAC 367
+++ +A+AGALK++ +LP+PL+ + L+ E ++A+ + ++ ++ AL
Sbjct: 1314 DHNINLASMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERFHALKEIV 1373
Query: 368 EKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVS 427
+K N++ RY+I L+++S+ +N MT N++I G L+ P E E ++T
Sbjct: 1374 KKFHPVNYDVFRYVITHLNRVSQQNKINLMTADNLSICFGQPLMRPDFENR--EFLSTTK 1431
Query: 428 LQIVGIIEPIIQHADWFF-PGEI 449
+ ++E IQ +FF GEI
Sbjct: 1432 IH-QSVVETFIQQCQFFFYNGEI 1453
>pir||A38218 GAP-associated protein p190 - rat
Length = 1493
Score = 97.9 bits (240), Expect = 4e-19
Identities = 73/257 (28%), Positives = 124/257 (47%), Gaps = 8/257 (3%)
Query: 238 PQIKAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSAS 297
P+ + W E FG PL +T + I IE C+ + G+ EG++RV+ + S
Sbjct: 1213 PRPSITKATW-ESNYFGVPLTTVVTPE-KPIPIFIERCIEYIEATGLSTEGIYRVSGNKS 1270
Query: 298 KLKKLKAALDCCV-VDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQ 356
+++ L+ D +D+ E + +AGA+KS+ EL + L+ + + + ++A + ++
Sbjct: 1271 EMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELRDRLVRYSMQIDLVEAHKINDR 1330
Query: 357 DKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAE 416
++KL AL +K PK NH +Y+I L+++S VN MT N++I P L+ P
Sbjct: 1331 EQKLHALKEVLKKFPKENHEVFKYVISHLNRVSHNNKVNLMTSENLSICFWPTLMRPDF- 1389
Query: 417 GNITEMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSPD 476
++ + T S Q IIE IQ +FF G +P+ H + SS
Sbjct: 1390 SSMDALTATRSYQT--IIELFIQQCPFFFYNRPISEPPGAALAPLQPWHPLSPSS--PLH 1445
Query: 477 MDPADRRQPEQARRPLS 493
+ P P +PLS
Sbjct: 1446 LLPVSHHLPSHLLQPLS 1462
>pir||T46471 hypothetical protein DKFZp434L0130.1 - human
emb|CAB70766.1| (AL137485) hypothetical protein [Homo sapiens]
Length = 316
Score = 96.0 bits (235), Expect = 1e-18
Identities = 74/277 (26%), Positives = 141/277 (50%), Gaps = 17/277 (6%)
Query: 165 LSSSLQPAGAKAD-ALREEMEEAANRVEICRDQLSAD---MYSFVAKEIDYANYFQTLIE 220
LSS++ + D + EE+ ++ + +++ D + SF ID + +T
Sbjct: 40 LSSTINNQAVETDEGIEEEIPDSPGIEKHDKEKEQKDPKKLRSFKVSSIDSSEQKKT--- 96
Query: 221 VQAEYHRKSLTLLQAVLPQIKAQQE-AWVEKPSFGKPLEEHLTISGREIAFPIEACVTML 279
+K+L P ++A +E +++ FG L + ++ C+ +
Sbjct: 97 ------KKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHV 150
Query: 280 LECGMQEEGLFRVAPSASKLKKLKAALDCCV-VDVQEYS-ADPHAIAGALKSYLRELPEP 337
E G+ +G++RV+ + + ++KL+ A++ +D+ + D H I GALK + RELPEP
Sbjct: 151 EEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEP 210
Query: 338 LMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKM 397
L TF +++++ A QE +++ A+ + +LPK N + ++ L + L ++ E + N+M
Sbjct: 211 LFTFNHFNDFVNAIK-QEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRM 269
Query: 398 TPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQIVGII 434
T ++AIV GP LL P+ E + T QIV +I
Sbjct: 270 TYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVELI 306
>pir||T31099 myosin-RhoGAP protein, Myr 7 - rat
emb|CAA04946.1| (AJ001713) myosin-RhoGAP protein, Myr 7 [Rattus norvegicus]
Length = 2626
Score = 96.0 bits (235), Expect = 1e-18
Identities = 50/159 (31%), Positives = 92/159 (57%), Gaps = 1/159 (0%)
Query: 253 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 312
FG L LT R + +E + + G+ EG++R + S +K+K+L+ LD
Sbjct: 2129 FGVELSR-LTSEDRAVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAES 2187
Query: 313 VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPK 372
V + H IA K +LR+LP PLMTFELY+E+++A +QE+ + ++ +++ ++L +
Sbjct: 2188 VNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSR 2247
Query: 373 ANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLL 411
+ + + LI L +++ +D N+M+ + +AIV P +L
Sbjct: 2248 THLSTLERLIFHLVRIALQEDTNRMSANALAIVFAPCIL 2286
>gb|AAF22154.1|AF133093_9 (AF133093) protein with characteristics of a rhoGAP [Mus musculus]
Length = 955
Score = 95.6 bits (234), Expect = 2e-18
Identities = 81/371 (21%), Positives = 162/371 (42%), Gaps = 51/371 (13%)
Query: 102 EDKLAQELIHFELQVE----RDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQ 157
+D++A+ LI EL E I+ +E + K K K +L+ +S
Sbjct: 353 DDEVAEVLIEMELWDEILPRAQNIQSRLDQKTIETEEVNKTLKATLKALLEAVAS----- 407
Query: 158 QTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQT 217
+ + SLQ + + + + R+Q ++ K +Y +
Sbjct: 408 ---EDGDILDSLQASPSTESLKSTSSDPGTRQTGRRRNQQQETETFYITKLQEYLSGRSI 464
Query: 218 LIEVQAEYHRKSLTLLQAVLPQIKAQQEAWVEKPS----------------FGKPLEEHL 261
L ++QA++ + + Q + + + E+ FG LE+ +
Sbjct: 465 LSKLQAKHEKLQEAIQQGNKEKQETSRTQCTERKFHKSHPPHPRFQYNQRLFGGDLEKFI 524
Query: 262 TISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALD---------CCVVD 312
SG+ + +E+C+ + G+Q EG+FRV+ + +++ +++ A + C V D
Sbjct: 525 QSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQARISEIRDAFERGEDPLEKGCTVHD 584
Query: 313 VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPK 372
+ ++AG LK Y R L PL ++++E + ++ ++ ++++ + + KLP+
Sbjct: 585 LD-------SVAGVLKLYFRSLEPPLFPLDMFNELLASAELEVVGERVEPVSHLLFKLPR 637
Query: 373 ANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQA-------EGNITEMMTT 425
+RYL FL+ L++Y D N M N+A+ GP LL A +G + +++ T
Sbjct: 638 PVLVVLRYLFTFLNHLAQYSDENMMDSYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQT 697
Query: 426 VSLQIVGIIEP 436
+ LQ I P
Sbjct: 698 LILQPARIFPP 708
>emb|CAA71414.2| (Y10388) Graf protein [Homo sapiens]
Length = 759
Score = 95.6 bits (234), Expect = 2e-18
Identities = 91/371 (24%), Positives = 158/371 (42%), Gaps = 44/371 (11%)
Query: 272 IEACVTMLLECGMQEEGLFRVAPSASKLKKLKAAL-----------DCCVVDVQEYSADP 320
I C+ + G+ E+GL+R+ S+++KL + L D C +
Sbjct: 393 IRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICA------EWEI 446
Query: 321 HAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRY 380
I ALK+YLR LP PLM ++ +I+A+ ++ Q+ ++ + + +LP+ N ++
Sbjct: 447 KTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQL 506
Query: 381 LIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQIVGIIEPIIQH 440
L+ L+ ++ N MT +N+ +V GP LL PQ E + +M IV IE +I++
Sbjct: 507 LMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEE-TVAAIMDIKFQNIV--IEILIEN 563
Query: 441 ADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSPDMDPADRRQPEQARRPLSVATDNMM 500
+ F + +T + +H++ + S P P + RPL++
Sbjct: 564 HEKIFNTVPDMPLT---NAQLHLSRKKSSDSKP-----------PSCSERPLTLFHTVQS 609
Query: 501 LEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAGRKVSCAPPSMQPPAPPAELAAPLPSPL 560
E ++ S+ + N + SS ++ + P + P + P P+P
Sbjct: 610 TEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLP-PNPS 668
Query: 561 PEQPLDSPAAPALS-------PSGLGLQPGPERTSTTKSKELSPGSAQKGSPGS-SQGTA 612
P PL SP+ P S S P T K+K L A+ S S + GT
Sbjct: 669 PTSPL-SPSWPMFSAPSSPMPTSSTSSDSSPVSTPFRKAKALYACKAEHDSELSFTAGTV 727
Query: 613 CAGTQPGAQPG 623
P +PG
Sbjct: 728 FDNVHPSQEPG 738
>pir||T39954 probable gtpase activating protein homolog - fission yeast
(Schizosaccharomyces pombe)
emb|CAA22624.1| (AL035065) putative gtpase activating protein homolog
[Schizosaccharomyces pombe]
Length = 695
Score = 95.2 bits (233), Expect = 3e-18
Identities = 53/182 (29%), Positives = 97/182 (53%), Gaps = 4/182 (2%)
Query: 253 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALD----C 308
FG L+ + I + C + + G+ +G++RV S++++ L++ +
Sbjct: 504 FGARLDAIILREHSNIPNIVMQCTSQVENFGLNLQGIYRVPSSSARVNMLRSQFENNPLL 563
Query: 309 CVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACE 368
+ ++Y D HA+A LK + REL EPL+ ++I A NV+++ ++ A+ A
Sbjct: 564 QLHTPEDYENDVHAVADLLKIFFRELREPLIPDNHQRDFIDAGNVEDESRRRDAVHRAIN 623
Query: 369 KLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSL 428
LP AN++ IR+L L+K+ E DVNKM+ +N+AI+ GP ++ I+ T+ +
Sbjct: 624 DLPDANYSTIRHLTIHLAKIKENSDVNKMSTNNLAIIWGPTIIKQATIPEISSFSRTIEI 683
Query: 429 QI 430
I
Sbjct: 684 LI 685
Score = 45.3 bits (105), Expect = 0.003
Identities = 46/172 (26%), Positives = 74/172 (42%), Gaps = 32/172 (18%)
Query: 529 GSSAGRKVSCAPPSMQPPAP---PAELAAPLPSPLPEQPLDSPAAPALSPSGLGLQPGPE 585
GSSAG+ P+++ A P + P PS P + SPA P S S P
Sbjct: 343 GSSAGKTNPPVNPTIKVTAAIPSPLQNTNPAPSTFPNPSVASPAFPNSSTSNPSTAPA-- 400
Query: 586 RTSTTKSKELSPGSAQKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQPP-ADQSPHTL 644
+++ + L P +A + SS ++ T + P AS + ++PP A QSP L
Sbjct: 401 -SASPLASTLKPSTANDTNGSSSSSSSNPRT-------SSPLASNAENKPPVAQQSPPVL 452
Query: 645 R-----------KVSKKLAPIPPKVPFGQPGAMADQSAGQLSPVSLSPTPPS 685
+ S+++AP P + ++++A P S+SP P S
Sbjct: 453 LPTLPPIQTTTIQTSREVAPPPSSI-------NSNRAASPFRPTSVSPQPSS 497
Score = 35.2 bits (79), Expect = 2.9
Identities = 48/164 (29%), Positives = 67/164 (40%), Gaps = 23/164 (14%)
Query: 587 TSTTKSKELSPGSAQKGSPGSSQGTACAGTQPGAQPGAQPGAS-PSPSQPPADQSPHTLR 645
T +K+K + P S+ GSS G T P P + A+ PSP Q + +P T
Sbjct: 326 TDASKTKIIQPPSSY--GTGSSAGK----TNPPVNPTIKVTAAIPSPLQN-TNPAPSTFP 378
Query: 646 KVSKKLAPIPPKVPFGQPGAMADQSAGQLSPVSLSPTPPSTPSPYGLSYPQGYSLASGQL 705
S +P P P +P S SP ST P + G S +S
Sbjct: 379 NPSVA-SPAFPNSSTSNPST---------APASASPLA-STLKPSTANDTNGSSSSSSS- 426
Query: 706 SPAAAPPLASPSVFTSTLSKSRPTPKPRQRPTLPPPQPPTVNLS 749
+P + PLAS + +++ P P PTLPP Q T+ S
Sbjct: 427 NPRTSSPLASNAENKPPVAQQSP---PVLLPTLPPIQTTTIQTS 467
>pir||T20802 hypothetical protein F12F6.5 - Caenorhabditis elegans
emb|CAA97790.1| (Z73425) Similarity to Human chimaerin (SW:CHIN_HUMAN), contains
similarity to Pfam domain: PF00620 (RhoGAP domain),
Score=155.8, E-value=2.4e-43, N=1~cDNA EST yk13f2.3
comes from this gene~cDNA EST yk4f9.3 comes from this
gene~cDNA EST yk4f9.5 comes f>
Length = 1059
Score = 95.2 bits (233), Expect = 3e-18
Identities = 61/217 (28%), Positives = 111/217 (51%), Gaps = 8/217 (3%)
Query: 253 FGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD 312
FG L+E++ +G EI +++ + L ++ +GLFRV+ S S++ + + A + D
Sbjct: 525 FGGSLDEYVEATGEEIPLLVQSAIAYLSRYSLRNQGLFRVSGSQSEINRFREAYERGE-D 583
Query: 313 VQEY---SADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEK 369
+ +Y +D ++ AG LK Y REL EP+ +++++ + + + ++ K
Sbjct: 584 LFQYLDDGSDANSAAGVLKLYFRELREPIFPIFMFEQFCDCAKSESPTEFVRRARELVSK 643
Query: 370 LPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQ 429
LP ++ +R+L FLS L E+ D N M P N+AI GP LL P EG +
Sbjct: 644 LPVSHVLLLRFLFAFLSHLCEFADENMMEPHNLAICFGPTLL-PIPEG---KDQVFYHNY 699
Query: 430 IVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHN 466
+ ++ +I HAD FP ++ + Y +++ N
Sbjct: 700 VNELVRNLIIHADDVFPRDLAGPVYDKYAMQRYMDGN 736
>gb|AAB60390.1| (U07000) breakpoint cluster region protein [Homo sapiens]
Length = 936
Score = 95.2 bits (233), Expect = 3e-18
Identities = 55/149 (36%), Positives = 83/149 (54%), Gaps = 2/149 (1%)
Query: 267 EIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSA--DPHAIA 324
++ + + CV + GM+E G++RV+ A+ ++ LKAA D DV + D +AIA
Sbjct: 731 KVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIA 790
Query: 325 GALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKF 384
G LK Y RELPEPL T E Y + + + + K + N LP+AN +L+
Sbjct: 791 GTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDH 850
Query: 385 LSKLSEYQDVNKMTPSNMAIVLGPNLLWP 413
L +++E + VNKM+ N+A V GP LL P
Sbjct: 851 LKRVAEKEAVNKMSLHNLATVFGPTLLRP 879
>gb|AAB60389.1| (U07000) breakpoint cluster region protein [Homo sapiens]
Length = 889
Score = 95.2 bits (233), Expect = 3e-18
Identities = 55/149 (36%), Positives = 83/149 (54%), Gaps = 2/149 (1%)
Query: 267 EIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSA--DPHAIA 324
++ + + CV + GM+E G++RV+ A+ ++ LKAA D DV + D +AIA
Sbjct: 684 KVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIA 743
Query: 325 GALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKF 384
G LK Y RELPEPL T E Y + + + + K + N LP+AN +L+
Sbjct: 744 GTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDH 803
Query: 385 LSKLSEYQDVNKMTPSNMAIVLGPNLLWP 413
L +++E + VNKM+ N+A V GP LL P
Sbjct: 804 LKRVAEKEAVNKMSLHNLATVFGPTLLRP 832
>ref|XP_009870.1| breakpoint cluster region, isoform 1 [Homo sapiens]
gb|AAB60388.1| (U07000) breakpoint cluster region protein [Homo sapiens]
Length = 1271
Score = 95.2 bits (233), Expect = 3e-18
Identities = 55/149 (36%), Positives = 83/149 (54%), Gaps = 2/149 (1%)
Query: 267 EIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSA--DPHAIA 324
++ + + CV + GM+E G++RV+ A+ ++ LKAA D DV + D +AIA
Sbjct: 1066 KVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIA 1125
Query: 325 GALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKF 384
G LK Y RELPEPL T E Y + + + + K + N LP+AN +L+
Sbjct: 1126 GTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDH 1185
Query: 385 LSKLSEYQDVNKMTPSNMAIVLGPNLLWP 413
L +++E + VNKM+ N+A V GP LL P
Sbjct: 1186 LKRVAEKEAVNKMSLHNLATVFGPTLLRP 1214
Database: nr
Posted date: Dec 10, 2000 7:21 PM
Number of letters in database: 188,047,558
Number of sequences in database: 594,795
Lambda K H
0.312 0.129 0.371
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 321188817
Number of Sequences: 594795
Number of extensions: 15716757
Number of successful extensions: 144989
Number of sequences better than 10.0: 5536
Number of HSP's better than 10.0 without gapping: 714
Number of HSP's successfully gapped in prelim test: 5015
Number of HSP's that attempted gapping in prelim test: 82132
Number of HSP's gapped (non-prelim): 27512
length of query: 818
length of database: 188,047,558
effective HSP length: 63
effective length of query: 755
effective length of database: 150,575,473
effective search space: 113684482115
effective search space used: 113684482115
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 42 (21.9 bits)
S2: 75 (33.6 bits)
