Score E
Sequences producing significant alignments: (bits) Value
ref|NP_006030.1| endocytic receptor (macrophage mannose rec... 3218 0.0
gb|AAD30280.1|AF134838_1 (AF134838) endocytic receptor Endo... 3218 0.0
ref|NP_032652.1| mannose receptor, C type 2; novel lectin [... 2853 0.0
ref|XP_008556.1| endocytic receptor (macrophage mannose rec... 2736 0.0
pir||A56395 secretory phospholipase A2 receptor precursor, ... 912 0.0
ref|NP_032651.1| mannose receptor, C type 1 [Mus musculus] ... 909 0.0
sp|P49259|PA2R_BOVIN 180 KD SECRETORY PHOSPHOLIPASE A2 RECE... 905 0.0
sp|P49260|PA2R_RABIT 180 KD SECRETORY PHOSPHOLIPASE A2 RECE... 905 0.0
pir||A48925 mannose receptor precursor, macrophage - mouse 901 0.0
ref|NP_032893.1| phospholipase A2, group IB, pancreas, rece... 889 0.0
ref|NP_002429.1| mannose receptor, C type 1 [Homo sapiens] ... 887 0.0
ref|XP_002318.1| phospholipase A2 receptor 1, 180kD [Homo s... 869 0.0
ref|NP_031392.1| phospholipase A2 receptor 1, 180kD [Homo s... 860 0.0
ref|NP_002340.1| lymphocyte antigen 75 [Homo sapiens] >gi|3... 754 0.0
gb|AAC62622.1| (AF064827) gp200-MR6 [Homo sapiens] 754 0.0
ref|NP_038853.1| lymphocyte antigen 75 [Mus musculus] >gi|2... 723 0.0
ref|XP_005830.1| mannose receptor, C type 1 [Homo sapiens] 681 0.0
dbj|BAA06445.1| (D30781) phospholipase A2 receptor [Rattus ... 282 2e-74
dbj|BAA06444.1| (D30780) phospholipase A2 receptor [Homo sa... 277 7e-73
ref|XP_002319.1| lymphocyte antigen 75 [Homo sapiens] 270 1e-70
gb|AAA29218.2| (L22612) tyrosine kinase receptor [Hydra vul... 192 3e-47
gb|AAC51365.1| (U58856) unknown [Homo sapiens] 189 2e-46
ref|NP_031450.1| aggrecan, structural proteoglycan of carti... 124 8e-27
ref|XP_007701.1| aggrecan 1, isoform 1 precursor [Homo sapi... 123 2e-26
gb|AAC25581.1| (AC005254) PGCN_HUMAN, PARTIAL CDS; 245 KD E... 123 2e-26
ref|NP_004377.1| chondroitin sulfate proteoglycan 3 (neuroc... 123 2e-26
ref|NP_001126.1| aggrecan 1, isoform 1 precursor; Aggrecan-... 123 2e-26
pir||A39086 aggrecan precursor - human 123 2e-26
pir||S62786 aggrecan - human (fragment) >gi|30249|emb|CAA35... 123 2e-26
gb|AAD24546.2| (AF116856) neurocan core protein precursor [... 121 5e-26
ref|NP_031815.1| chondroitin sulfate proteoglycan 3 [Mus mu... 121 5e-26
sp|P55067|PGCN_RAT NEUROCAN CORE PROTEIN PRECURSOR (245 KDA... 121 5e-26
sp|P07897|PGCA_RAT AGGRECAN CORE PROTEIN PRECURSOR (CARTILA... 120 1e-25
pir||T42630 aggrecan - bovine >gi|1730260|gb|AAB38524.1| (U... 119 2e-25
pir||A39808 proteoglycan core protein, cartilage - bovine (... 119 2e-25
gb|AAA21000.1| (J03485) aggrecan [Rattus norvegicus] 118 4e-25
gb|AAA41836.1| (M13518) proteoglycan [Rattus norvegicus] 118 4e-25
ref|XP_007700.1| aggrecan 1, isoform 2 precursor [Homo sapi... 118 6e-25
gb|AAB06238.2| (U65989) articular cartilage aggrecan precur... 118 6e-25
sp|P13608|PGCA_BOVIN AGGRECAN CORE PROTEIN PRECURSOR (CARTI... 118 6e-25
sp||PGCA_CANFA_2 [Segment 2 of 2] AGGRECAN CORE PROTEIN (CA... 118 6e-25
pir||S08042 proteoglycan core protein long splice form, car... 118 6e-25
sp|P16112|PGCA_HUMAN AGGRECAN CORE PROTEIN PRECURSOR (CARTI... 118 6e-25
ref|NP_037359.1| aggrecan 1, isoform 1 precursor; Aggrecan-... 117 8e-25
gb|AAA35726.1| (J05062) proteoglycan core protein [Homo sap... 117 8e-25
gb|AAA48719.1| (J04028) proteoglycan core protein [Gallus g... 116 2e-24
gb|AAC60053.1| (U78555) chondroitin sulfate proteoglycan co... 115 4e-24
emb|CAA42701.1| (X60107) cartilage aggregating proteoglycan... 115 4e-24
pir||S39796 aggrecan precursor - chicken 115 4e-24
sp|P07898|PGCA_CHICK AGGRECAN CORE PROTEIN PRECURSOR (CARTI... 115 4e-24
>ref|NP_006030.1| endocytic receptor (macrophage mannose receptor family); KIAA0709
gene product [Homo sapiens]
dbj|BAA31684.1| (AB014609) KIAA0709 protein [Homo sapiens]
gb|AAF14192.1|AF107292_1 (AF107292) urokinase receptor-associated protein uPARAP [Homo
sapiens]
Length = 1479
Score = 3218 bits (8251), Expect = 0.0
Identities = 1479/1479 (100%), Positives = 1479/1479 (100%)
Query: 1 MGPGRPAPAPWPRHLLRCVLLLGCLHLGRPGAPGDAALPEPNVFLIFSHGLQGCLEAQGG 60
MGPGRPAPAPWPRHLLRCVLLLGCLHLGRPGAPGDAALPEPNVFLIFSHGLQGCLEAQGG
Sbjct: 1 MGPGRPAPAPWPRHLLRCVLLLGCLHLGRPGAPGDAALPEPNVFLIFSHGLQGCLEAQGG 60
Query: 61 QVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLR 120
QVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLR
Sbjct: 61 QVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLR 120
Query: 121 WHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQG 180
WHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQG
Sbjct: 121 WHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQG 180
Query: 181 NSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWD 240
NSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWD
Sbjct: 181 NSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWD 240
Query: 241 KDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGL 300
KDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGL
Sbjct: 241 KDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGL 300
Query: 301 NDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCK 360
NDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCK
Sbjct: 301 NDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCK 360
Query: 361 KKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSI 420
KKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSI
Sbjct: 361 KKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSI 420
Query: 421 HSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLED 480
HSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLED
Sbjct: 421 HSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLED 480
Query: 481 CVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQV 540
CVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQV
Sbjct: 481 CVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQV 540
Query: 541 TYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDE 600
TYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDE
Sbjct: 541 TYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDE 600
Query: 601 VMYTHWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPD 660
VMYTHWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPD
Sbjct: 601 VMYTHWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPD 660
Query: 661 PTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEE 720
PTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEE
Sbjct: 661 PTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEE 720
Query: 721 HFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDD 780
HFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDD
Sbjct: 721 HFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDD 780
Query: 781 DIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFF 840
DIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFF
Sbjct: 781 DIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFF 840
Query: 841 EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRF 900
EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRF
Sbjct: 841 EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRF 900
Query: 901 RWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQ 960
RWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQ
Sbjct: 901 RWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQ 960
Query: 961 PPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQ 1020
PPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQ
Sbjct: 961 PPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQ 1020
Query: 1021 AFITASLPNVTFDLWIGLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAV 1080
AFITASLPNVTFDLWIGLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAV
Sbjct: 1021 AFITASLPNVTFDLWIGLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAV 1080
Query: 1081 VLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLL 1140
VLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLL
Sbjct: 1081 VLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLL 1140
Query: 1141 QKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVS 1200
QKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVS
Sbjct: 1141 QKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVS 1200
Query: 1201 EEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGS 1260
EEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGS
Sbjct: 1201 EEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGS 1260
Query: 1261 CPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQS 1320
CPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQS
Sbjct: 1261 CPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQS 1320
Query: 1321 YEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWR 1380
YEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWR
Sbjct: 1321 YEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWR 1380
Query: 1381 PGACTNITMGVVCKLPRAEQSSFSPSALPENPAALVVVLMAVLLLLALLTAALILYRRRQ 1440
PGACTNITMGVVCKLPRAEQSSFSPSALPENPAALVVVLMAVLLLLALLTAALILYRRRQ
Sbjct: 1381 PGACTNITMGVVCKLPRAEQSSFSPSALPENPAALVVVLMAVLLLLALLTAALILYRRRQ 1440
Query: 1441 SIERGAFEGARYSRSSSSPTEATEKNILVSDMEMNEQQE 1479
SIERGAFEGARYSRSSSSPTEATEKNILVSDMEMNEQQE
Sbjct: 1441 SIERGAFEGARYSRSSSSPTEATEKNILVSDMEMNEQQE 1479
>gb|AAD30280.1|AF134838_1 (AF134838) endocytic receptor Endo180 [Homo sapiens]
Length = 1479
Score = 3218 bits (8250), Expect = 0.0
Identities = 1478/1479 (99%), Positives = 1479/1479 (99%)
Query: 1 MGPGRPAPAPWPRHLLRCVLLLGCLHLGRPGAPGDAALPEPNVFLIFSHGLQGCLEAQGG 60
MGPGRPAPAPWPRHLLRCVLLLGCLHLGRPGAPGDAALPEPN+FLIFSHGLQGCLEAQGG
Sbjct: 1 MGPGRPAPAPWPRHLLRCVLLLGCLHLGRPGAPGDAALPEPNIFLIFSHGLQGCLEAQGG 60
Query: 61 QVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLR 120
QVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLR
Sbjct: 61 QVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLR 120
Query: 121 WHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQG 180
WHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQG
Sbjct: 121 WHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQG 180
Query: 181 NSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWD 240
NSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWD
Sbjct: 181 NSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWD 240
Query: 241 KDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGL 300
KDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGL
Sbjct: 241 KDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGL 300
Query: 301 NDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCK 360
NDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCK
Sbjct: 301 NDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCK 360
Query: 361 KKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSI 420
KKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSI
Sbjct: 361 KKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSI 420
Query: 421 HSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLED 480
HSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLED
Sbjct: 421 HSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLED 480
Query: 481 CVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQV 540
CVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQV
Sbjct: 481 CVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQV 540
Query: 541 TYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDE 600
TYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDE
Sbjct: 541 TYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDE 600
Query: 601 VMYTHWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPD 660
VMYTHWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPD
Sbjct: 601 VMYTHWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPD 660
Query: 661 PTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEE 720
PTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEE
Sbjct: 661 PTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEE 720
Query: 721 HFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDD 780
HFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDD
Sbjct: 721 HFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDD 780
Query: 781 DIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFF 840
DIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFF
Sbjct: 781 DIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFF 840
Query: 841 EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRF 900
EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRF
Sbjct: 841 EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRF 900
Query: 901 RWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQ 960
RWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQ
Sbjct: 901 RWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQ 960
Query: 961 PPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQ 1020
PPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQ
Sbjct: 961 PPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQ 1020
Query: 1021 AFITASLPNVTFDLWIGLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAV 1080
AFITASLPNVTFDLWIGLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAV
Sbjct: 1021 AFITASLPNVTFDLWIGLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAV 1080
Query: 1081 VLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLL 1140
VLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLL
Sbjct: 1081 VLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLL 1140
Query: 1141 QKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVS 1200
QKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVS
Sbjct: 1141 QKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVS 1200
Query: 1201 EEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGS 1260
EEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGS
Sbjct: 1201 EEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGS 1260
Query: 1261 CPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQS 1320
CPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQS
Sbjct: 1261 CPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQS 1320
Query: 1321 YEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWR 1380
YEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWR
Sbjct: 1321 YEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWR 1380
Query: 1381 PGACTNITMGVVCKLPRAEQSSFSPSALPENPAALVVVLMAVLLLLALLTAALILYRRRQ 1440
PGACTNITMGVVCKLPRAEQSSFSPSALPENPAALVVVLMAVLLLLALLTAALILYRRRQ
Sbjct: 1381 PGACTNITMGVVCKLPRAEQSSFSPSALPENPAALVVVLMAVLLLLALLTAALILYRRRQ 1440
Query: 1441 SIERGAFEGARYSRSSSSPTEATEKNILVSDMEMNEQQE 1479
SIERGAFEGARYSRSSSSPTEATEKNILVSDMEMNEQQE
Sbjct: 1441 SIERGAFEGARYSRSSSSPTEATEKNILVSDMEMNEQQE 1479
>ref|NP_032652.1| mannose receptor, C type 2; novel lectin [Mus musculus]
pir||T42710 mannose receptor, macrophage - mouse
gb|AAC52729.1| (U56734) lectin lambda [Mus musculus]
Length = 1479
Score = 2853 bits (7314), Expect = 0.0
Identities = 1319/1481 (89%), Positives = 1364/1481 (92%), Gaps = 4/1481 (0%)
Query: 1 MGPGRPAPAPWPRHLLRCVLLLGCLHLGRPGAPGDAALPEPNVFLIFSHGLQGCLEAQGG 60
M P RPA APWPRHLLRCVLLLG L LG P A AAL EP+VFLIFS G+QGCLEAQG
Sbjct: 1 MVPIRPALAPWPRHLLRCVLLLGGLRLGHP-ADSAAALLEPDVFLIFSQGMQGCLEAQGV 59
Query: 61 QVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLR 120
QVRVTP CN SLPAQRWKWVSRNRLFNLG QCLGTGWP TNTT SLGMYECDREAL+LR
Sbjct: 60 QVRVTPFCNASLPAQRWKWVSRNRLFNLGATQCLGTGWPVTNTTVSLGMYECDREALSLR 119
Query: 121 WHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQG 180
+ G + LERGDQTRSG W IYGSEEDLCA PY+EVYTIQG
Sbjct: 120 MAVSYTRGPVVPASGGSCKQCIQAWHLERGDQTRSGHWNIYGSEEDLCARPYYEVYTIQG 179
Query: 181 NSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWD 240
NSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWD
Sbjct: 180 NSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWD 239
Query: 241 KDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGL 300
KDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGL
Sbjct: 240 KDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGL 299
Query: 301 NDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCK 360
NDLDTSGGWQWSDNSPLKYLNWESDQPDNP EENCGVIRTESSGGWQN DCSIALPYVCK
Sbjct: 300 NDLDTSGGWQWSDNSPLKYLNWESDQPDNPGEENCGVIRTESSGGWQNHDCSIALPYVCK 359
Query: 361 KKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSI 420
KKPNAT EP PDRW NVKVEC+PSWQPFQGHCYRLQAEKRSWQESK+ACLRGGGDL+SI
Sbjct: 360 KKPNATVEPIQPDRWTNVKVECDPSWQPFQGHCYRLQAEKRSWQESKRACLRGGGDLLSI 419
Query: 421 HSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLED 480
HSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLED
Sbjct: 420 HSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLED 479
Query: 481 CVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQV 540
CVTIWGPEGRWNDSPCNQSLPSICKKAG+LSQGAAEEDH CRKGWTWHSPSCYWLGEDQV
Sbjct: 480 CVTIWGPEGRWNDSPCNQSLPSICKKAGRLSQGAAEEDHDCRKGWTWHSPSCYWLGEDQV 539
Query: 541 TYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDE 600
YS+ARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSF WLSGDE
Sbjct: 540 IYSDARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFRWLSGDE 599
Query: 601 VMYTHWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPD 660
V+YTHWNRDQPGY RGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPD
Sbjct: 600 VIYTHWNRDQPGYRRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPD 659
Query: 661 PTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEE 720
PTPSLTGSCPQGW SD KLR+CYKVFSSERLQ+KKSW+QA G C+ELGAQLLSLASYEEE
Sbjct: 660 PTPSLTGSCPQGWVSDPKLRHCYKVFSSERLQEKKSWIQALGVCRELGAQLLSLASYEEE 719
Query: 721 HFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDD 780
HFVA+MLNKIFGESEPE HEQHWFWIGLNRRDPR G SWRWSDG+GFSYHNF RSRHDDD
Sbjct: 720 HFVAHMLNKIFGESEPESHEQHWFWIGLNRRDPREGHSWRWSDGLGFSYHNFARSRHDDD 779
Query: 781 DIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFF 840
DIRGCAVLDLASLQWV MQC TQLDWICKIPRG DVREPD QGR EW+RFQEAEYKFF
Sbjct: 780 DIRGCAVLDLASLQWVPMQCQTQLDWICKIPRGVDVREPDIGRQGRLEWVRFQEAEYKFF 839
Query: 841 EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRF 900
EHHS+WAQAQRICTWFQA+LTSVHSQAEL FL NLQK S QEQHWWIGLHT ESDGRF
Sbjct: 840 EHHSSWAQAQRICTWFQADLTSVHSQAELGFLGQNLQKLSSDQEQHWWIGLHTLESDGRF 899
Query: 901 RWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQ 960
RWTDGSIINFISWAPGKPRP+GKDKKCVYMTA +EDWGDQRC TALPYICKRSN + ETQ
Sbjct: 900 RWTDGSIINFISWAPGKPRPIGKDKKCVYMTARQEDWGDQRCHTALPYICKRSNSSGETQ 959
Query: 961 PPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQ 1020
P DLP +ALGGCPS W QFLNKCF++QGQ+PQ RVKWSEAQFSCEQQEAQLVTI NPLEQ
Sbjct: 960 PQDLPPSALGGCPSGWNQFLNKCFRIQGQDPQDRVKWSEAQFSCEQQEAQLVTIANPLEQ 1019
Query: 1021 AFITASLPNVTFDLWIGLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAV 1080
AFITASLPNVTFDLWIGLHASQRDFQW+EQEPL+Y NWAPGEPSGPSPAPSG KPTSCAV
Sbjct: 1020 AFITASLPNVTFDLWIGLHASQRDFQWIEQEPLLYTNWAPGEPSGPSPAPSGTKPTSCAV 1079
Query: 1081 VLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLL 1140
+LHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAA PPAPG ELSYLN TFRLL
Sbjct: 1080 ILHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAATPPAPGAELSYLNHTFRLL 1139
Query: 1141 QKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVS 1200
QKPLRW DALLLCES NASLA+VPDPYTQAFLTQAARGL+TPLWIGLA EEGSRRYSW+S
Sbjct: 1140 QKPLRWKDALLLCESRNASLAHVPDPYTQAFLTQAARGLQTPLWIGLASEEGSRRYSWLS 1199
Query: 1201 EEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGS 1260
EEPLNYV WQD EPQ GGC YVDVDG WRTTSCDTKLQGAVCGVS G PPPRRI+Y GS
Sbjct: 1200 EEPLNYVSWQDEEPQHSGGCAYVDVDGTWRTTSCDTKLQGAVCGVSRG-PPPRRINYRGS 1258
Query: 1261 CPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQS 1320
CPQGLADS+WIPFREHCYSFHME+LLGHKEA QRCQ+AGG VLSILDEMENVFVWEHLQ+
Sbjct: 1259 CPQGLADSSWIPFREHCYSFHMEVLLGHKEALQRCQKAGGTVLSILDEMENVFVWEHLQT 1318
Query: 1321 YEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWR 1380
E QSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQS+SGLWR
Sbjct: 1319 AEAQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSSSGLWR 1378
Query: 1381 PGACTNITMGVVCKLPRAEQSSFSPS-ALPENPAALVVVLMAVLLLLALLTAALILYRRR 1439
PGACTNITMGVVCKLPR E++SF PS ALPE+P ALVVVL AVLLLLAL+TAALILYRRR
Sbjct: 1379 PGACTNITMGVVCKLPRVEENSFLPSAALPESPVALVVVLTAVLLLLALMTAALILYRRR 1438
Query: 1440 QSIERGAFEGARYSRSS-SSPTEATEKNILVSDMEMNEQQE 1479
QS ERG+FEGARYSRSS S P EATEKNILVSDMEMNEQQE
Sbjct: 1439 QSAERGSFEGARYSRSSHSGPAEATEKNILVSDMEMNEQQE 1479
>ref|XP_008556.1| endocytic receptor (macrophage mannose receptor family) [Homo
sapiens]
Length = 1362
Score = 2736 bits (7013), Expect = 0.0
Identities = 1247/1248 (99%), Positives = 1248/1248 (99%)
Query: 1 MGPGRPAPAPWPRHLLRCVLLLGCLHLGRPGAPGDAALPEPNVFLIFSHGLQGCLEAQGG 60
MGPGRPAPAPWPRHLLRCVLLLGCLHLGRPGAPGDAALPEPN+FLIFSHGLQGCLEAQGG
Sbjct: 1 MGPGRPAPAPWPRHLLRCVLLLGCLHLGRPGAPGDAALPEPNIFLIFSHGLQGCLEAQGG 60
Query: 61 QVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLR 120
QVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLR
Sbjct: 61 QVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLR 120
Query: 121 WHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQG 180
WHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQG
Sbjct: 121 WHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQG 180
Query: 181 NSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWD 240
NSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWD
Sbjct: 181 NSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWD 240
Query: 241 KDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGL 300
KDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGL
Sbjct: 241 KDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGL 300
Query: 301 NDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCK 360
NDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCK
Sbjct: 301 NDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCK 360
Query: 361 KKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSI 420
KKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSI
Sbjct: 361 KKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSI 420
Query: 421 HSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLED 480
HSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLED
Sbjct: 421 HSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLED 480
Query: 481 CVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQV 540
CVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQV
Sbjct: 481 CVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQV 540
Query: 541 TYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDE 600
TYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDE
Sbjct: 541 TYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDE 600
Query: 601 VMYTHWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPD 660
VMYTHWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPD
Sbjct: 601 VMYTHWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPD 660
Query: 661 PTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEE 720
PTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEE
Sbjct: 661 PTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEE 720
Query: 721 HFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDD 780
HFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDD
Sbjct: 721 HFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDD 780
Query: 781 DIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFF 840
DIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFF
Sbjct: 781 DIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFF 840
Query: 841 EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRF 900
EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRF
Sbjct: 841 EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRF 900
Query: 901 RWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQ 960
RWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQ
Sbjct: 901 RWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQ 960
Query: 961 PPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQ 1020
PPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQ
Sbjct: 961 PPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQ 1020
Query: 1021 AFITASLPNVTFDLWIGLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAV 1080
AFITASLPNVTFDLWIGLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAV
Sbjct: 1021 AFITASLPNVTFDLWIGLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAV 1080
Query: 1081 VLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLL 1140
VLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLL
Sbjct: 1081 VLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLL 1140
Query: 1141 QKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVS 1200
QKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVS
Sbjct: 1141 QKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVS 1200
Query: 1201 EEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSG 1248
EEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSG
Sbjct: 1201 EEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSG 1248
Score = 302 bits (765), Expect = 2e-80
Identities = 281/1108 (25%), Positives = 450/1108 (40%), Gaps = 162/1108 (14%)
Query: 373 DRWANVKV---ECEPSWQPFQ--GHCYRLQAEKR-SWQESKKACLRGGGDLVSIHSMAEL 426
+RW + +CE W Q CY+ + SW+E+ +C + G DL+SI + E
Sbjct: 223 ERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQ 282
Query: 427 EFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTI-W 485
+I + LWIGLNDL ++WSD S + + +W +P+N S E+C I
Sbjct: 283 TYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRT 340
Query: 486 GPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHG------CRKGWTWHSPSCYWLGEDQ 539
G W + C+ +LP +CKK + D C W CY L ++
Sbjct: 341 ESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEK 400
Query: 540 VTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGD 599
++ E+++ C G LV+I + E F++ I E E W L DL +F W G
Sbjct: 401 RSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQ-EVEELWIGLNDLKLQMNFEWSDGS 459
Query: 600 EVMYTHWNRDQPGYSRGG---CVALATGSAMGLWEVKNCTSFRARYICRQS--LGTPVTP 654
V +THW+ +P R CV + G W C IC+++ L
Sbjct: 460 LVSFTHWHPFEPNNFRDSLEDCVTI--WGPEGRWNDSPCNQSLPS-ICKKAGQLSQGAAE 516
Query: 655 ELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSL 714
E G C +GW + CY + +D+ ++ +A+ C + G+QL+++
Sbjct: 517 EDHG----------CRKGWTWHSPS--CYWLG-----EDQVTYSEARRLCTDHGSQLVTI 559
Query: 715 ASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDR 774
+ E+ FV++++ GE +FW L + G W D V +++ N D+
Sbjct: 560 TNRFEQAFVSSLIYNWEGE---------YFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQ 610
Query: 775 SRHDDDDIRGCAVLDLASLQ--WVAMQCDT-QLDWICKIPRGTDVRE----PDDSP---- 823
+ GC L S W C + + +IC+ GT V PD +P
Sbjct: 611 PGYSRG---GCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTG 667
Query: 824 ---QGRREWLRFQEAEYKFF-----EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHN 875
QG + + YK F + +W QAQ C A+L S+ S E F+++
Sbjct: 668 SCPQGWASDTKLRYC-YKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANM 726
Query: 876 LQKF-----SRAQEQHW-WIGLHTSESDG--RFRWTDGSIINFISWAPGKPRPVGKD-KK 926
L K EQHW WIGL+ + G +RW+DG ++ ++ + R D +
Sbjct: 727 LNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNF--DRSRHDDDDIRG 784
Query: 927 CVYMTASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQV 986
C + + W +C T L +ICK T +P D P +W++F ++
Sbjct: 785 CAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGR-----REWLRFQEAEYKF 839
Query: 987 QGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTF----DLWIGLHASQ 1042
+ W++AQ C +A+L ++ + E F++ +L + WIGLH S+
Sbjct: 840 F----EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSE 895
Query: 1043 RD--FQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTE 1100
D F+W + + + +WAPG+P P G K C + S W D+ C
Sbjct: 896 SDGRFRWTDGSIINFISWAPGKPR-----PVG-KDKKCVYMTASRED-----WGDQRCLT 944
Query: 1101 ETHGFICQ-----KGTDPSLSPSPAALPPAPGTELSYLNGTFRLL----QKPLRWHDALL 1151
+IC+ K T P P+ AL P + +LN F++ Q ++W +A
Sbjct: 945 ALP-YICKRSNVTKETQPPDLPT-TALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQF 1002
Query: 1152 LCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQD 1211
CE A L + +P QAF+T + + LWIGL + R + WV +EPL Y W
Sbjct: 1003 SCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLHASQ--RDFQWVEQEPLMYANWAP 1060
Query: 1212 GEPQ---------QPGGCTYV------DVDGAWRTTSCDTKLQGAVCGVSSGP---PPPR 1253
GEP +P C V G W SC + G +C + P P P
Sbjct: 1061 GEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPA 1120
Query: 1254 RISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVF 1313
+ A + + + + L H +A C+ ++ + D F
Sbjct: 1121 ALPP--------APGTELSYLNGTFRLLQKPLRWH-DALLLCESHNASLAYVPDPYTQAF 1171
Query: 1314 VWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNW--GPPGLGPSMLSHNSCYW 1371
+ Q+ G W+G+ W +NY W G P C +
Sbjct: 1172 L---TQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQ------QPGGCTY 1222
Query: 1372 IQSNSGLWRPGACTNITMGVVCKLPRAE 1399
+ + G WR +C G VC + E
Sbjct: 1223 VDVD-GAWRTTSCDTKLQGAVCGVSSGE 1249
Score = 238 bits (601), Expect = 4e-61
Identities = 224/950 (23%), Positives = 387/950 (40%), Gaps = 110/950 (11%)
Query: 531 SCYWLG-EDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNS 589
SCY + +++ EA C G+ L++IT EQ +++ L+ + W L DL++
Sbjct: 247 SCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSST-LWIGLNDLDT 305
Query: 590 TGSFFWLSGDEVMYTHWNRDQPGY-SRGGCVALATGSAMGLWEVKNCTSFRARYICRQSL 648
+G + W + Y +W DQP S C + T S+ G W+ ++C S Y+C++
Sbjct: 306 SGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGG-WQNRDC-SIALPYVCKKKP 363
Query: 649 GTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELG 708
T E PD ++ C W +CY++ + +K+SW +++ AC G
Sbjct: 364 NA--TAEPTPPDRWANVKVECEPSWQPFQG--HCYRLQA-----EKRSWQESKKACLRGG 414
Query: 709 AQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDG--VG 766
L+S+ S E F+ + + E+ E WIGLN D + ++ WSDG V
Sbjct: 415 GDLVSIHSMAELEFITKQIKQ-------EVEE---LWIGLN--DLKLQMNFEWSDGSLVS 462
Query: 767 FSYHNFDRSRHDDDDIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGR 826
F++ + + D + C + +W C+ L ICK ++ R
Sbjct: 463 FTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCR 522
Query: 827 REWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQH 886
+ W + Y E T+++A+R+CT ++L ++ ++ E F+S + + + ++
Sbjct: 523 KGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNW---EGEY 579
Query: 887 WWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASRED--WGDQRCLT 944
+W L S G F W G + + W + +P CV + W + C +
Sbjct: 580 FWTALQDLNSTGSFFWLSGDEVMYTHW--NRDQPGYSRGGCVALATGSAMGLWEVKNCTS 637
Query: 945 -ALPYICKRS---NVTKETQPPDLPTTALGGCPSDWIQF--LNKCFQVQGQEP-QSRVKW 997
YIC++S VT E PD + G CP W L C++V E Q + W
Sbjct: 638 FRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSW 697
Query: 998 SEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTFD----------LWIGLHASQ----R 1043
+AQ +C++ AQL+++ + E+ F+ L + + WIGL+ +
Sbjct: 698 VQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQ 757
Query: 1044 DFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETH 1103
++W + Y N+ + CAV+ + +W C +
Sbjct: 758 SWRWSDGVGFSYHNFDRSRHDD-------DDIRGCAVLDLASL-----QWVAMQCDTQLD 805
Query: 1104 GFICQ--KGTDPSLSPSPAALPPAPGTELSYLNGTFRLLQKPLRWHDALLLCESHNASLA 1161
+IC+ +GTD P P L + ++ + W A +C A L
Sbjct: 806 -WICKIPRGTDVR---EPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELT 861
Query: 1162 YVPDPYTQAFLT----QAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQP 1217
V FL+ + +R WIGL E R+ W +N++ W G+P+
Sbjct: 862 SVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPV 921
Query: 1218 GG---CTYVDVDGA-WRTTSCDTKLQGAVCGVSS----GPPPPRRISYHGSCPQGLADSA 1269
G C Y+ W C T L +C S+ PP + G CP S
Sbjct: 922 GKDKKCVYMTASREDWGDQRCLTALP-YICKRSNVTKETQPPDLPTTALGGCP-----SD 975
Query: 1270 WIPFREHCYSFH---MELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSR 1326
WI F C+ + + EA+ C++ +++I + +E F+ L + +
Sbjct: 976 WIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNV---TF 1032
Query: 1327 GAWLGMNFNPKGGTLVWQDNTAVNYSNWGP-----PGLGPSMLSHNSCYWIQSN-----S 1376
W+G++ + + W + + Y+NW P P PS SC + + +
Sbjct: 1033 DLWIGLHASQRD--FQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFT 1090
Query: 1377 GLWRPGACTNITMGVVCKLPRAEQSSFSPSALPENPAALVVVLMAVLLLL 1426
G W +CT T G +C+ S SP+ALP P + L LL
Sbjct: 1091 GRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLL 1140
>pir||A56395 secretory phospholipase A2 receptor precursor, transmembrane form -
human
gb|AAA70110.1| (U17033) 180 kDa transmembrane PLA2 receptor precursor [Homo sapiens]
Length = 1465
Score = 912 bits (2330), Expect = 0.0
Identities = 513/1479 (34%), Positives = 773/1479 (51%), Gaps = 91/1479 (6%)
Query: 40 EPNVFLIFSHGLQGCLEAQGGQVRVTPACNTSLPAQR---WKWVSRNRLFNLGTMQCLGT 96
+ +F+I S L+ C++A G+ +T S A + WKWVS + LFN+G CLG
Sbjct: 37 DKGIFVIQSESLKKCIQA--GKSVLTLGRTGSKQANKHMLWKWVSNHGLFNIGGSGCLGL 94
Query: 97 GWPGTNTTASLGMYECDREALNLRWHCR----TLGDQLSLLLGARTSNISKPGTLERGDQ 152
+ SL YECD ++LRW C T Q S+ + + ++ + +
Sbjct: 95 NFSAPEQPLSL--YECDSTLVSLRWRCNRKMITGPLQYSVQVAHDNTVVASRKYIHK--- 149
Query: 153 TRSGQWRIYGSEE-DLCALPYHEVYTIQGNSHGKPCTIPFKYDNQWFHGCTSTGREDGHL 211
W YGS D+C + +++TI+GN+HG PC PF+Y++QW H CT GRED L
Sbjct: 150 -----WISYGSGGGDICEYLHKDLHTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLL 204
Query: 212 WCATTQDYGKDERWGFCPIKSN---DCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQ 268
WCATT Y +DE+WGFCP ++ C+T W+KD + CYQFN S+LSW EA +SC+
Sbjct: 205 WCATTSRYERDEKWGFCPDPTSAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQM 264
Query: 269 QGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPD 328
QG LLSIT+ E+ +I ++ + +W+GLN LD GWQWSD +PL YLNW +
Sbjct: 265 QGGTLLSITDETEENFIREHMSSKTVEVWVGLNQLDEDAGWQWSDGTPLNYLNWSPEVNF 324
Query: 329 NP-SEENCGVIRTESSGGWQNRDCSIALPYVCKKKPN-ATAEPTPPDRWANVKVECEPSW 386
P E++CG + W++RDC LPY+CKK N E D W CEP W
Sbjct: 325 EPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGW 384
Query: 387 QPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQE-VEELWIGLN 445
P+ +CY+LQ E+++W E+ ++C L+ I S+AE+EF+ + E E WIGL+
Sbjct: 385 NPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASETWIGLS 444
Query: 446 DLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSICK 505
K+ ++FEWS+ S V FT+WH EP+ F + + CV+ EG W C + L ICK
Sbjct: 445 SNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFYICK 504
Query: 506 KAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARR--LCTDHGSQLVTITNRF 563
KAG + ++ + GC++GW CY + ++ +A C LVTITNRF
Sbjct: 505 KAGHV---LSDAESGCQEGWEETCGFCYKIDTVLRSFDQASSGYYCP---PALVTITNRF 558
Query: 564 EQAFVSSLI---YNWEGEYFWTALQDLNSTGSFFW----LSGDEVMYTHWNRDQPGYSRG 616
EQAF++SLI + YFW ALQD N TG + W + V YTHWN QP YS G
Sbjct: 559 EQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYS-G 617
Query: 617 GCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASD 676
GCVA+ +G WEVK+C F+A +C+Q + E P C W S+
Sbjct: 618 GCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWP----FHPCYLDWESE 673
Query: 677 TKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEP 736
L C+KVF SE++ K++W +A+ C+E GA L S A EEE+FV +L+ F +
Sbjct: 674 PGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHPKFNWT-- 731
Query: 737 EIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRGCAVLDLASLQWV 796
E+ FWIG N+R+P SW WSD +F + + +D R CAV + +
Sbjct: 732 ---EERQFWIGFNKRNPLNAGSWEWSDRTPV-VSSFLDNTYFGEDARNCAVYK-PNKTLL 786
Query: 797 AMQCDTQLDWICKIPRGTDVREP----DDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRI 852
+ C ++ +WICKIPR + P D P WL +Q+AEY F S W + +
Sbjct: 787 PLHCGSKREWICKIPRDVKPKIPFWYQYDVP-----WLFYQDAEYLFHTFASEWLNFEFV 841
Query: 853 CTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFIS 912
C+W ++L ++HS E +F+ ++ S+ WWIGL ++ FRW DG+ + + +
Sbjct: 842 CSWLHSDLLTIHSAHEQEFIHSKIKALSK-YGASWWIGLQEERANDEFRWRDGTPVIYQN 900
Query: 913 WAPGKPRPV-GKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGG 971
W G+ R V + ++C ++++ WG + C ++P ICKR V + D P G
Sbjct: 901 WDTGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQH-GT 959
Query: 972 CPSDWIQFLNKCFQVQ-GQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNV 1030
CP W+ F KC + ++P S W+ AQ C ++ LV I + +EQAFIT +L
Sbjct: 960 CPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQ 1019
Query: 1031 TFDLWIGLHASQRDFQWVEQEPLMYANWAPGE----PSGPSPAPSGNKPTSCAVVLHSPS 1086
T +WIGL + W+ +P++Y+NW+P + PS + + P CA++ +P+
Sbjct: 1020 TTSVWIGLQNDDYE-TWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPL-CALLSSNPN 1077
Query: 1087 AHFTGRWDDRSCTEETHGFICQKGTDPS-LSPSPAALPPAPGTELSYLNGTFRLLQKPLR 1145
HFTG+W C +E +GF+C+K D S + + + P P T L Y N T++++ +
Sbjct: 1078 FHFTGKWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNT-LEYGNRTYKIINANMT 1136
Query: 1146 WHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLN 1205
W+ A+ C H A L + D Y Q+FLT L WIGL + + W +
Sbjct: 1137 WYAAIKTCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSS 1196
Query: 1206 YVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGSCPQGL 1265
+ W+D E G C + D +G W +T+CD+ LQGA+C V PP R+ + C +
Sbjct: 1197 FTFWKDEESSLLGDCVFADSNGRWHSTACDSFLQGAICHV---PPETRQSEHPELCSE-- 1251
Query: 1266 ADSAWIPFREHCYSFHMEL-LLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQ 1324
WI F+ +CY F L + + A + C++ G +L+I DE EN F+ E L ++
Sbjct: 1252 TSIPWIKFKSNCYKFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENAFLLEELFAFGSS 1311
Query: 1325 SRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGAC 1384
+ WL F+ T+ W D T + SNWG + C ++ GLW+ C
Sbjct: 1312 VQMVWLNAQFDGNNETIKWFDGTPTDQSNWGIRKPDTDYFKPHHCVALRIPEGLWQLSPC 1371
Query: 1385 TNITMGVVCKLPRAEQSSFSPSALPENPAALVVVLMAVLL----LLALLTAALILYRRRQ 1440
G +CK+ E + ALPE + ++ +AV+L ++A+ T + +Y+
Sbjct: 1372 QE-KKGFICKM---EADIHTAEALPEKGPSHSIIPLAVVLTLIVIVAICTLSFCIYKHNG 1427
Query: 1441 SIER--GAFEGARYSRSSSSPTEATEKNILVSDMEMNEQ 1477
R F Y ++ S T E+NIL+SD+E ++Q
Sbjct: 1428 GFFRRLAGFRNPYYPATNFS-TVYLEENILISDLEKSDQ 1465
>ref|NP_032651.1| mannose receptor, C type 1 [Mus musculus]
emb|CAA78028.1| (Z11974) macrophage mannose receptor precursor [Mus musculus]
Length = 1456
Score = 909 bits (2323), Expect = 0.0
Identities = 510/1498 (34%), Positives = 782/1498 (52%), Gaps = 83/1498 (5%)
Query: 16 LRCVLLLGCLHLGRPGAPGDAALPEPNVFLIFSHGLQGCLEAQGGQVRVTPACNTSLPAQ 75
+R +LLL + + P L + FLI++ + C++A T CN +Q
Sbjct: 1 MRLLLLLAFISV----IPVSVQLLDARQFLIYNEDHKRCVDALSAISVQTATCNPEAESQ 56
Query: 76 RWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLRWHCRT------LGDQ 129
+++WVS +++ ++ CLG P AS+ +Y CD ++ +W C+ G +
Sbjct: 57 KFRWVSDSQIMSVAFKLCLGV--PSKTDWASVTLYACDSKSEYQKWECKNDTLFGIKGTE 114
Query: 130 LSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQGNSHGKPCTI 189
L G R K L +G S +W++YG+ +DLC+ Y +Y++ GN++G C
Sbjct: 115 LYFNYGNRQEKNIK---LYKGSGLWS-RWKVYGTTDDLCSRGYEAMYSLLGNANGAVCAF 170
Query: 190 PFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCY 249
PFK++N+W+ CTS GR DG LWC TT DY KD+ +GFCP+ E W+KD LT Y
Sbjct: 171 PFKFENKWYADCTSAGRSDGWLWCGTTTDYDKDKLFGFCPLHFEGSERLWNKDPLTGILY 230
Query: 250 QFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGW 309
Q N +S L+W +A ASC+QQ ADLLS+TEIHEQ Y+ GL + SS LWIGLN L GW
Sbjct: 231 QINSKSALTWHQARASCKQQNADLLSVTEIHEQMYLTGLTSSLSSGLWIGLNSLSVRSGW 290
Query: 310 QWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEP 369
QW+ SP +YLNW P + ++C + + W+N +C L Y+C KK N T P
Sbjct: 291 QWAGGSPFRYLNWLPGSPSSEPGKSCVSLNPGKNAKWENLECVQKLGYIC-KKGNNTLNP 349
Query: 370 TPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQE-SKKACLRGGGDLVSIHSMAELEF 428
++V C W P+ GHCYR+ E++ Q+ + +AC + GGDL SIHS+ E +F
Sbjct: 350 FIIPSASDVPTGCPNQWWPYAGHCYRIHREEKKIQKYALQACRKEGGDLASIHSIEEFDF 409
Query: 429 ITKQIKQEV-EELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGP 487
I Q+ E +ELWIGLND+K+QM FEWSDG+ V+FT W P EP++ + EDCV + G
Sbjct: 410 IFSQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLPGEPSHENNRQEDCVVMKGK 469
Query: 488 EGRWNDSPCNQSLPSICKKAGQLSQGAAE-EDHGCRKGWTWHSPSCYWLGEDQVTYSEAR 546
+G W D C Q L ICK Q E D GCRKGW H CY +G T+++A
Sbjct: 470 DGYWADRACEQPLGYICKMVSQSHAVVPEGADKGCRKGWKRHGFYCYLIGSTLSTFTDAN 529
Query: 547 RLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDEVMYTHW 606
CT+ + L T+ +R+EQAF++SL+ +YFWT L D+ + G+F W ++V +THW
Sbjct: 530 HTCTNEKAYLTTVEDRYEQAFLTSLVGLRPEKYFWTGLSDVQNKGTFRWTVDEQVQFTHW 589
Query: 607 NRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLT 666
N D PG + GCVA+ TG A GLW+V +C +A+++C+ P P+PT +
Sbjct: 590 NADMPG-RKAGCVAMKTGVAGGLWDVLSCEE-KAKFVCKHWAEGVTRP----PEPTTTPE 643
Query: 667 GSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANM 726
CP+ W + +K C+K+++ + +KK+W +++ C+ +G +L S+ S +E+ + +
Sbjct: 644 PKCPENWGTTSKTSMCFKLYAKGK-HEKKTWFESRDFCKAIGGELASIKSKDEQQVIWRL 702
Query: 727 LNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDD-DDIRGC 785
+ S HE FW+GL P G + WSDG SY N+ ++ ++ C
Sbjct: 703 IT-----SSGSYHE--LFWLGLTYGSPSEG--FTWSDGSPVSYENWAYGEPNNYQNVEYC 753
Query: 786 AVL-DLASLQWVAMQCDTQLDWICKIPRG-TDVREPDDSPQGRRE-----WLRFQEAEYK 838
L + W + C+ +WIC+I +G T + EP +PQ W+ +++ +Y
Sbjct: 754 GELKGDPGMSWNDINCEHLNNWICQIQKGKTLLPEPTPAPQDNPPVTADGWVIYKDYQYY 813
Query: 839 FFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDG 898
F + T A+R C +L ++ S++E FL + K + ++IG+ S D
Sbjct: 814 FSKEKETMDNARRFCKKNFGDLATIKSESEKKFLWKYINK--NGGQSPYFIGMLIS-MDK 870
Query: 899 RFRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVT-K 957
+F W DGS ++F++WA G+P D+ CV M + W D C +IC+R N +
Sbjct: 871 KFIWMDGSKVDFVAWATGEPNFANDDENCVTMYTNSGFWNDINCGYPNNFICQRHNSSIN 930
Query: 958 ETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNP 1017
T P PTT GGC W + NKCF++ G + + W +A+ +C+ + LV+I N
Sbjct: 931 ATAMPTTPTTP-GGCKEGWHLYKNKCFKIFGFANEEKKSWQDARQACKGLKGNLVSIENA 989
Query: 1018 LEQAFITASLPNVTFDLWIGLH--ASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKP 1075
EQAF+T + + TF+ W GL+ ++ F W + + Y NW G P G + S +
Sbjct: 990 QEQAFVTYHMRDSTFNAWTGLNDINAEHMFLWTAGQGVHYTNWGKGYPGGRRSSLS-YED 1048
Query: 1076 TSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNG 1135
C VV+ S G W D +C + G+ICQ TDPSL SP P ++Y
Sbjct: 1049 ADCVVVIGGNSRE-AGTWMDDTC-DSKQGYICQTQTDPSLPVSPTTTP--KDGFVTYGKS 1104
Query: 1136 TFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRR 1195
++ L++ L WH+A C+ H + LA + DPY+ AF P+WI L +
Sbjct: 1105 SYSLMKLKLPWHEAETYCKDHTSLLASILDPYSNAFAWMKMHPFNVPIWIALNSNLTNNE 1164
Query: 1196 YSWVSEEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRI 1255
Y+W + Y W EP+ C Y+DVDG WRT+ C+ +C S P
Sbjct: 1165 YTWTDRWRVRYTNWGADEPKLKSACVYMDVDGYWRTSYCNESFY-FLCKKSDEIPATEPP 1223
Query: 1256 SYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVW 1315
G CP+ +AWIPF HCY F +A C R G +++SI E+ F+
Sbjct: 1224 QLPGKCPES-EQTAWIPFYGHCYYFESSFTRSWGQASLECLRMGASLVSIETAAESSFLS 1282
Query: 1316 EHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSN 1375
++ + ++ W+GM N +G L W ++ V++ NW G N C + S+
Sbjct: 1283 YRVEPLKSKT-NFWIGMFRNVEGKWL-WLNDNPVSFVNW---KTGDPSGERNDCVVLASS 1337
Query: 1376 SGLWRPGACTNITMGVVCKLP--------------RAEQSSFSPSALPENPAALVVVLMA 1421
SGLW C++ G +CK+P +A+Q P + AA VV ++
Sbjct: 1338 SGLWNNIHCSSY-KGFICKMPKIIDPVTTHSSITTKADQRKMDPQPKGSSKAAGVVTVV- 1395
Query: 1422 VLLLLALLTAALILYRRRQSI---ERGAFEGARYSRSSSSPTEATEKNILVSDMEMNE 1476
+L+++ AA Y++R ++ + FE Y S+ SP + K+ L+ ++E NE
Sbjct: 1396 LLIVIGAGVAAYFFYKKRHALHIPQEATFENTLYFNSNLSPGTSDTKD-LMGNIEQNE 1452
>sp|P49259|PA2R_BOVIN 180 KD SECRETORY PHOSPHOLIPASE A2 RECEPTOR PRECURSOR (PLA2-R)
pir||A53210 phospholipase A2 receptor precursor - bovine
dbj|BAA03683.1| (D16109) phospholipase A2 receptor [Bos taurus]
Length = 1463
Score = 905 bits (2314), Expect = 0.0
Identities = 522/1477 (35%), Positives = 771/1477 (51%), Gaps = 89/1477 (6%)
Query: 40 EPNVFLIFSHGLQGCLEAQGGQVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWP 99
+ +F+I S L+ C++A + + C WKWVS +RLFN+G CLG
Sbjct: 37 DKGIFIIQSENLEKCIQASKSTLTLEN-CKPPNKYMLWKWVSNHRLFNIGGSGCLGLNV- 94
Query: 100 GTNTTASLGMYECDREALNLRWHC--RTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQ 157
++ L +YECD ++L+WHC +T+ L L+ + N TL + +
Sbjct: 95 -SSPEQPLSIYECDSTHVSLKWHCNKKTITGPLQYLVQVKQDN-----TLV-ASRKYLHK 147
Query: 158 WRIYGSEED-LCALPYHEVYTIQGNSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATT 216
W Y S +C + ++YTI+GN+HG PC PF+Y+ QW H CT GRED LWCATT
Sbjct: 148 WVSYMSGGGGICDYLHKDLYTIKGNAHGTPCMFPFQYNQQWHHECTREGREDNLLWCATT 207
Query: 217 QDYGKDERWGFCPIKSND---CETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADL 273
Y +DE+WGFCP ++ C+ W+KD + CYQFN S+LSW EA +SC+ QGA L
Sbjct: 208 SRYERDEKWGFCPDPTSTEVGCDAVWEKDLHSRICYQFNLLSSLSWSEAHSSCQMQGAAL 267
Query: 274 LSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDNP-SE 332
LSI + E+ ++ L + +W+GLN LD GWQWSD +PL YLNW+ + P E
Sbjct: 268 LSIADETEENFVRKHLGSEAVEVWMGLNQLDEDAGWQWSDRTPLNYLNWKPEINFEPFVE 327
Query: 333 ENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAE-PTPPDRWANVKVECEPSWQPFQG 391
+CG W++RDC LPYVCKK N T D W CEP W P
Sbjct: 328 YHCGTFNAFMPKAWKSRDCESTLPYVCKKYLNPTDHGVVEKDAWKYYATHCEPGWNPHNR 387
Query: 392 HCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQE-VEELWIGLNDLKLQ 450
+CY+LQ EK++W E+ ++C L I S+AE+EF+ + E E WIGL+ K+
Sbjct: 388 NCYKLQKEKKTWNEALQSCQSNNSVLTDITSLAEVEFLVTLLGDENASETWIGLSSHKIP 447
Query: 451 MNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSICKKAGQL 510
++FEWS+GS V+FT+WH EP+ F + + CV+ EG W C ++L +CKK G +
Sbjct: 448 VSFEWSNGSSVTFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEETLFYLCKKTGLV 507
Query: 511 SQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQ-------LVTITNRF 563
++ + GC+KGW H CY + D V S DH S L+TIT+RF
Sbjct: 508 ---LSDTESGCQKGWERHGKFCYKI--DTVLRS------FDHASSGYYCPPALITITSRF 556
Query: 564 EQAFVSSLI---YNWEGEYFWTALQDLNSTGSFFWLSG----DEVMYTHWNRDQPGYSRG 616
EQAF++SLI + YFW ALQD N+TG + W + + V YTHWN QP YS G
Sbjct: 557 EQAFITSLISSVVKTKDTYFWIALQDQNNTGEYTWKTAGQQLEPVKYTHWNTRQPRYS-G 615
Query: 617 GCVALATGSAMGLWEVKNCTSFRARYICRQSL-GTPVTPELPGPDPTPSLTGSCPQGWAS 675
GCV + S G WEV++C F+A +C+Q + T + G P C W S
Sbjct: 616 GCVVMRGRSHPGRWEVRDCRHFKAMSLCKQPVENREKTKQEEGWPFHP-----CYLDWES 670
Query: 676 DTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESE 735
+ L C+KVF SE++ K++W QA+ C+E GA L S A EEE+FV +L+ F +
Sbjct: 671 EPGLASCFKVFHSEKVLMKRTWRQAEEFCEEFGAHLASFAHIEEENFVNELLHSKFNRT- 729
Query: 736 PEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRGCAVLDLASLQW 795
E+ FWIG N+R+P SW WSDG D S + +D R CAV A+
Sbjct: 730 ----EERQFWIGFNKRNPLNAGSWEWSDGTPVVSSFLDNS-YFGEDARNCAVYK-ANKTL 783
Query: 796 VAMQCDTQLDWICKIPRGTDVREPDDSP--QGRREWLRFQEAEYKFFEHHSTWAQAQRIC 853
+ C ++ +WICKIPR DVR P P Q WL +Q+AEY F S W+ + +C
Sbjct: 784 LPSYCGSKREWICKIPR--DVR-PKVPPWYQYDAPWLFYQDAEYLFHISASEWSSFEFVC 840
Query: 854 TWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISW 913
W ++++ ++HS E +F+ ++ S+ +WWIGL + FRW DGS + + +W
Sbjct: 841 GWLRSDILTIHSAHEQEFIHSKIRALSK-YGVNWWIGLREERASDEFRWRDGSPVIYQNW 899
Query: 914 APGKPRPVG--KDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGG 971
GK R +G + ++C ++++ W + C ++P ICKR V + D+P G
Sbjct: 900 DKGKERSMGLNESQRCGFISSITGLWASEECSISMPSICKRKKVWVIEKKKDIPKQH-GT 958
Query: 972 CPSDWIQFLNKCFQVQGQE-PQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNV 1030
CP W+ F KC ++ E P W+ AQ C ++ LV I N +EQAFIT +L
Sbjct: 959 CPKGWLYFDYKCLLLKIPEGPSDWKNWTSAQDFCVEEGGTLVAIENEVEQAFITMNLFGH 1018
Query: 1031 TFDLWIGLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGN------KPTSCAVVLHS 1084
T ++WIGL + +W+ P+ Y+NW+P + P+ N + C ++ ++
Sbjct: 1019 TTNVWIGLQDDDYE-KWLNGRPVSYSNWSPFDTKN---IPNHNTTEVQKRIPLCGLLSNN 1074
Query: 1085 PSAHFTGRWDDRSCTEETHGFICQKGTDPS-LSPSPAALPPAPGTELSYLNGTFRLLQKP 1143
P+ HFTG+W C E +GF+C+K D S S + + + P P T L Y N T++++
Sbjct: 1075 PNFHFTGKWYFEDC-REGYGFVCEKMQDASGHSINTSDMYPIPNT-LEYGNRTYKIINAN 1132
Query: 1144 LRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEP 1203
+ W+ AL C H A LA + D Y Q+FLT + WIGL E+ + W
Sbjct: 1133 MTWYTALKTCLMHGAELASITDQYHQSFLTVILNRVGYAHWIGLFTEDNGLSFDWSDGTK 1192
Query: 1204 LNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGSCPQ 1263
++ W+D E G C + D G W +T+C++ LQGA+C V P R C +
Sbjct: 1193 SSFTFWKDDESSFLGDCVFADTSGRWSSTACESYLQGAICQV---PTETRLSGRLELCSE 1249
Query: 1264 GLADSAWIPFREHCYSFHMEL-LLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYE 1322
WI F+ +CYSF L + A + C++ G +L+I DE EN F+ E L ++
Sbjct: 1250 --TSIPWIKFKSNCYSFSTVLESTSFEAAHEFCKKKGSNLLTIKDEAENSFLLEELLAFR 1307
Query: 1323 GQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPG 1382
+ WL F+ T+ W D T + SNWG + C ++ G+W+
Sbjct: 1308 SSVQMIWLNAQFDGDNETIKWFDGTPTDQSNWGIRKPEVYHFKPHLCVALRIPEGVWQLS 1367
Query: 1383 ACTNITMGVVCKLPR-AEQSSFSPSALPENPAALVVVLMAVLLLLALLTAALILYRRRQS 1441
+C + G +CK+ P P + + V + +L++LA+ T + +Y+
Sbjct: 1368 SCQD-KKGFICKMEADIHTVKKHPGKGPSHSVIPLTVALTLLVILAISTLSFCMYKHSHI 1426
Query: 1442 I-ERGAFEGARYSRSSSSPTEATEKNILVSDMEMNEQ 1477
I R A Y S++ T E+NIL+SD+E N+Q
Sbjct: 1427 IFGRLAQFRNPYYPSANFSTVHLEENILISDLEKNDQ 1463
>sp|P49260|PA2R_RABIT 180 KD SECRETORY PHOSPHOLIPASE A2 RECEPTOR PRECURSOR (PLA2-R)
pir||A49707 phospholipase A2 receptor precursor - rabbit
gb|AAC48402.1| (U03455) 180 kda phospholipase A2 receptor precursor [Oryctolagus
cuniculus]
Length = 1458
Score = 905 bits (2314), Expect = 0.0
Identities = 502/1474 (34%), Positives = 771/1474 (52%), Gaps = 87/1474 (5%)
Query: 40 EPNVFLIFSHGLQGCLEAQGGQVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWP 99
E +F+I S L+ C++A G V +C WKWVS LFN+G CLG
Sbjct: 35 EKGIFIIQSESLKSCIQA-GKSVLTLESCKQPNKNMLWKWVSNQHLFNIGGSGCLGLNL- 92
Query: 100 GTNTTASLGMYECDREALNLRWHCRTLGDQLSLLLGARTSNIS-KPGTLERGDQTRSGQW 158
+N LG+YECD ++LRW C ++ G + K + R +W
Sbjct: 93 -SNPEQPLGLYECDSTHVSLRWRCNR-----KMITGPLQHTVQVKQDNIIVASGKRLHKW 146
Query: 159 RIYGSEE-DLCALPYHEVYTIQGNSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQ 217
Y S+ D+C + ++YT +GN+HG PC PF+Y++QW H CT GR+D LWCATT
Sbjct: 147 ISYMSDSGDICQHVHKDLYTRKGNAHGTPCMFPFQYNHQWHHECTREGRQDDSLWCATTS 206
Query: 218 DYGKDERWGFCPIKSN---DCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLL 274
Y +DE+WGFCP ++ C+ W+KD + CYQFN S+LSW EA +SC+ G LL
Sbjct: 207 RYERDEKWGFCPDPTSAEVGCDAVWEKDLNSHICYQFNLLSSLSWSEAHSSCQMHGGALL 266
Query: 275 SITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDNP-SEE 333
SI + E+ +I ++G + +W GLN LD + GWQWSD +PL YLNW + P E
Sbjct: 267 SIVDEAEENFIRKQVSGEAVEVWTGLNQLDVNAGWQWSDGTPLSYLNWSPEISFEPFVEY 326
Query: 334 NCGVIRTESSGGWQNRDCSIALPYVCKKKPN-ATAEPTPPDRWANVKVECEPSWQPFQGH 392
+CG + W++R+C LPY+CKK N E D W +CEP W P+ +
Sbjct: 327 HCGTFNSFMPRAWRSRNCESTLPYICKKYLNHVDDEIVEKDAWKYYATDCEPGWAPYHRN 386
Query: 393 CYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQE-VEELWIGLNDLKLQM 451
CY+LQ E+++W E+ +CL L+ I S+AE+EF+ + E E WIGL+ +
Sbjct: 387 CYKLQKEEKTWNEALHSCLSSNSTLIDIGSLAEVEFLVTLLGNENASETWIGLSSNTFPV 446
Query: 452 NFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSICKKAGQLS 511
+FEWS+GS V FT+WH EP F + + CV+ EG W + C ++ +CKK G +
Sbjct: 447 SFEWSNGSSVIFTNWHTLEPQIFPNRSQLCVSAEQSEGHWKVTDCEETHFYVCKKPGHV- 505
Query: 512 QGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQ-------LVTITNRFE 564
++ + GC++GW H CY + D V S DH S LVTI +RFE
Sbjct: 506 --LSDAESGCQEGWERHGGFCYKI--DTVLRS------FDHASSGYYCPPALVTIADRFE 555
Query: 565 QAFVSSLI---YNWEGEYFWTALQDLNSTGSFFWLS----GDEVMYTHWNRDQPGYSRGG 617
QAF++SLI N + YFW ALQD N TG + W + + V YTHWN QP S GG
Sbjct: 556 QAFITSLISSVVNMKDSYFWIALQDQNDTGEYTWKTAGQKSEPVQYTHWNAHQP-RSSGG 614
Query: 618 CVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDT 677
CVA+ + +G WEVK+C F+A +C+Q + T E P C W S
Sbjct: 615 CVAIRGRNPIGRWEVKDCVHFKAMSLCKQPVETREKMEHEERWP----FHPCYLDWESQP 670
Query: 678 KLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEPE 737
L C+KVF SE++ K++W +A+ C+E GA L S A EEE+FV +L+ F S
Sbjct: 671 GLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHPKFNRS--- 727
Query: 738 IHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRGCAVLDLASLQWVA 797
E+ FWIG N+R+P SW WSDG +F + + +D R CAV A+ +
Sbjct: 728 --EERQFWIGFNKRNPLNAGSWEWSDGTPV-ISSFLDNNYFGEDTRNCAVYK-ANKTLLP 783
Query: 798 MQCDTQLDWICKIPRGTDVREPD----DSPQGRREWLRFQEAEYKFFEHHSTWAQAQRIC 853
+ C ++ +WICKIPR + P D+P WL Q+AEY F+ H S W+ + +C
Sbjct: 784 LHCGSKREWICKIPRDVRPKIPSWYQYDAP-----WLFHQDAEYLFYPHSSEWSSFEFVC 838
Query: 854 TWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISW 913
W ++++ ++HS E +F+ ++ S+ +WWIGL ++ RW DG+ + + +W
Sbjct: 839 GWLRSDILTIHSAHEQEFILSKIKALSK-YGANWWIGLQEETANDELRWRDGTPVIYQNW 897
Query: 914 APGKPRPV-GKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGC 972
+ R + + ++C ++++ W + C ++P ICKR + D P G C
Sbjct: 898 DKERDRSMNNQSQRCAFISSITGLWDREECSVSMPSICKRKTFWVIEKEKDTPKQH-GTC 956
Query: 973 PSDWIQFLNKCFQVQ-GQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT 1031
P W+ F KC V ++P + W++A+ C + LV I + +EQAFIT +L T
Sbjct: 957 PKGWLYFDYKCLLVNVPKDPSNWKNWTQARDFCFDEGGTLVAIESEVEQAFITMNLFGQT 1016
Query: 1032 FDLWIGLHASQRDFQWVEQEPLMYANWAPGE----PSGPSPAPSGNKPTSCAVVLHSPSA 1087
++WIGL + +W+ P+ Y+NW+P + PS + A P CA++ +P+
Sbjct: 1017 TNVWIGLQNDDYE-KWLNGNPVAYSNWSPSDIINIPSYNTTADQKPIPL-CALLSSNPNF 1074
Query: 1088 HFTGRWDDRSCTEETHGFICQKGTDPS-LSPSPAALPPAPGTELSYLNGTFRLLQKPLRW 1146
HFTG+W C +E +GF+C+K D + + + + P P T L Y N T++++ + W
Sbjct: 1075 HFTGKWYFEDCGKEGYGFVCEKIQDSAGHEVNTSIMDPIPNT-LEYGNRTYKIINANMTW 1133
Query: 1147 HDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNY 1206
+ A+ C+ H A L + D Y Q+FLT L WIGL + + W ++
Sbjct: 1134 YAAIKSCQLHGAELVSITDQYHQSFLTVILSRLGHAHWIGLFTADNGLHFDWSDGTKSSF 1193
Query: 1207 VGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGSCPQGLA 1266
W+D + G C + D G W +T+C++ LQGA+C V P R + C +
Sbjct: 1194 TFWKDEDSSFLGDCVFADTSGRWHSTACESFLQGAICHV---PTETRPFEHPELCSE--T 1248
Query: 1267 DSAWIPFREHCYSFHMEL-LLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQS 1325
WI F+ +CYSF L + A + C++ G +L+I DE EN F+ E ++
Sbjct: 1249 SIPWIKFKSNCYSFSTVLHSASFEAAHEFCKKEGSNLLTIKDEAENSFLLEEPFAFGASV 1308
Query: 1326 RGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGACT 1385
+ WL F+ + T+ W D T + SNWG + + C ++ G+W+ C
Sbjct: 1309 QMVWLNAQFDNE--TVKWLDGTPADQSNWGIRKPDMAHFEPHQCLALRIPEGVWQLSPCQ 1366
Query: 1386 NITMGVVCKLPRAEQSSFS--PSALPENPAALVVVLMAVLLLLALLTAALILYRRRQS-I 1442
MG +CK+ +A+ + P P + + V + ++++LA++T + +Y++ +
Sbjct: 1367 K-NMGFICKM-KADIHTVKEHPGKGPSHSIVPLAVALTLVVILAIITLSFYIYKQNKGFF 1424
Query: 1443 ERGAFEGARYSRSSSSPTEATEKNILVSDMEMNE 1476
R A G Y +++ T E+NIL+SD+E N+
Sbjct: 1425 RRLAGVGNSYYPTTNFSTIHLEENILISDLEKND 1458
>pir||A48925 mannose receptor precursor, macrophage - mouse
Length = 1455
Score = 901 bits (2303), Expect = 0.0
Identities = 512/1501 (34%), Positives = 783/1501 (52%), Gaps = 90/1501 (5%)
Query: 16 LRCVLLLGCLHLGRPGAPGDAALPEPNVFLIFSHGLQGCLEAQGGQVRVTPACNTSLPAQ 75
+R +LLL + + P L + FLI++ + C++A T CN +Q
Sbjct: 1 MRLLLLLAFISV----IPVSVQLLDARQFLIYNEDHKRCVDALSAISVQTATCNPEAESQ 56
Query: 76 RWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLRWHCRT------LGDQ 129
+++WVS +++ ++ CLG P AS+ +Y CD ++ +W C+ G +
Sbjct: 57 KFRWVSDSQIMSVAFKLCLGV--PSKTDWASVTLYACDSKSEYQKWECKNDTLFGIKGTE 114
Query: 130 LSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQGNSHGKPCTI 189
L G R K L +G S +W++YG+ +DLC+ Y +Y++ GN++G C
Sbjct: 115 LYFNYGNRQEKNIK---LYKGSGLWS-RWKVYGTTDDLCSRGYEAMYSLLGNANGAVCAF 170
Query: 190 PFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCY 249
PFK++N+W+ CTS GR DG LWC TT DY KD+ +GFCP+ E W+KD LT Y
Sbjct: 171 PFKFENKWYADCTSAGRSDGWLWCGTTTDYDKDKLFGFCPLHFEGSERLWNKDPLTGILY 230
Query: 250 QFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGW 309
Q N +S L+W +A ASC+QQ ADLLS+TEIHEQ Y+ GL + SS LWIGLN L GW
Sbjct: 231 QINSKSALTWHQARASCKQQNADLLSVTEIHEQMYLTGLTSSLSSGLWIGLNSLSVRSGW 290
Query: 310 QWSDNSPLKYLNWESDQPDNPSEE---NCGVIRTESSGGWQNRDCSIALPYVCKKKPNAT 366
QW+ SP +YLN P +PS E +C + + W+N +C L Y+C KK N T
Sbjct: 291 QWAGGSPFRYLN----LPGSPSSEPGKSCVSLNPGKNAKWENLECVQKLGYIC-KKGNNT 345
Query: 367 AEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQE-SKKACLRGGGDLVSIHSMAE 425
P ++V C W P+ GHCYR+ E++ Q+ + +AC + GGDL SIHS+ E
Sbjct: 346 LNPFIIPSASDVPTGCPNQWWPYAGHCYRIHREEKKIQKYALQACRKEGGDLASIHSIEE 405
Query: 426 LEFITKQIKQEV-EELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTI 484
+FI Q+ E +ELWIGLND+K+QM FEWSDG+ V+FT W P EP++ + EDCV +
Sbjct: 406 FDFIFSQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLPGEPSHENNRQEDCVVM 465
Query: 485 WGPEGRWNDSPCNQSLPSICKKAGQLSQGAAE-EDHGCRKGWTWHSPSCYWLGEDQVTYS 543
G +G W D C Q L ICK Q E D GCRKGW H CY +G T++
Sbjct: 466 KGKDGYWADRACEQPLGYICKMVSQSHAVVPEGADKGCRKGWKRHGFYCYLIGSTLSTFT 525
Query: 544 EARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDEVMY 603
+A CT+ + L T+ +R+EQAF++SL+ +YFWT L D+ + G+F W ++V +
Sbjct: 526 DANHTCTNEKAYLTTVEDRYEQAFLTSLVGLRPEKYFWTGLSDVQNKGTFRWTVDEQVQF 585
Query: 604 THWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTP 663
THWN D PG + GCVA+ TG A GLW+V +C +A+++C+ P P+PT
Sbjct: 586 THWNADMPG-RKAGCVAMKTGVAGGLWDVLSCEE-KAKFVCKHWAEGVTRP----PEPTT 639
Query: 664 SLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFV 723
+ CP+ W + +K C+K+++ + +KK+W +++ C+ +G +L S+ S +E+ +
Sbjct: 640 TPEPKCPENWGTTSKTSMCFKLYAKGK-HEKKTWFESRDFCKAIGGELASIKSKDEQQVI 698
Query: 724 ANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDD-DDI 782
++ S HE FW+GL P G + WSDG SY N+ ++ ++
Sbjct: 699 WRLIT-----SSGSYHE--LFWLGLTYGSPSEG--FTWSDGSPVSYENWAYGEPNNYQNV 749
Query: 783 RGCAVL-DLASLQWVAMQCDTQLDWICKIPRG-TDVREPDDSPQGRRE-----WLRFQEA 835
C L + W + C+ +WIC+I +G T + EP +PQ W+ +++
Sbjct: 750 EYCGELKGDPGMSWNDINCEHLNNWICQIQKGKTLLPEPTPAPQDNPPVTADGWVIYKDY 809
Query: 836 EYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSE 895
+Y F + T A+R C +L ++ S++E FL + K + ++IG+ S
Sbjct: 810 QYYFSKEKETMDNARRFCKKNFGDLATIKSESEKKFLWKYINK--NGGQSPYFIGMLIS- 866
Query: 896 SDGRFRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNV 955
D +F W DGS ++F++WA G+P D+ CV M + W D C +IC+R N
Sbjct: 867 MDKKFIWMDGSKVDFVAWATGEPNFANDDENCVTMYTNSGFWNDINCGYPNNFICQRHNS 926
Query: 956 T-KETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTI 1014
+ T P PTT GGC W + NKCF++ G + + W +A+ +C+ + LV+I
Sbjct: 927 SINATAMPTTPTTP-GGCKEGWHLYKNKCFKIFGFANEEKKSWQDARQACKGLKGNLVSI 985
Query: 1015 TNPLEQAFITASLPNVTFDLWIGLH--ASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSG 1072
N EQAF+T + + TF+ W GL+ ++ F W + + Y NW G P G + S
Sbjct: 986 ENAQEQAFVTYHMRDSTFNAWTGLNDINAEHMFLWTAGQGVHYTNWGKGYPGGRRSSLS- 1044
Query: 1073 NKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSY 1132
+ C VV+ S G W D +C + G+ICQ TDPSL SP P ++Y
Sbjct: 1045 YEDADCVVVIGGNSRE-AGTWMDDTC-DSKQGYICQTQTDPSLPVSPTTTP--KDGFVTY 1100
Query: 1133 LNGTFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEG 1192
++ L++ L WH+A C+ H + LA + DPY+ AF P+WI L
Sbjct: 1101 GKSSYSLMKLKLPWHEAGTYCKDHTSLLASILDPYSNAFAWMKMHPFNVPIWIALNSNLT 1160
Query: 1193 SRRYSWVSEEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPP 1252
+ Y+W + Y W EP+ C Y+DVDG WRT+ C+ +C S P
Sbjct: 1161 NNEYTWTDRWRVRYTNWGADEPKLKSACVYMDVDGYWRTSYCNESFY-FLCKKSDEIPAT 1219
Query: 1253 RRISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENV 1312
G CP+ +AWIPF HCY F +A C R G +++SI E+
Sbjct: 1220 EPPQLPGKCPES-EQTAWIPFYGHCYYFESSFTRSWGQASLECLRMGASLVSIETAAESS 1278
Query: 1313 FVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWI 1372
F+ ++ + ++ W+GM N +G L W ++ V++ NW G N C +
Sbjct: 1279 FLSYRVEPLKSKT-NFWIGMFRNVEGKWL-WLNDNPVSFVNW---KTGDPSGERNDCVVL 1333
Query: 1373 QSNSGLWRPGACTNITMGVVCKLP--------------RAEQSSFSPSALPENPAALVVV 1418
S+SGLW C++ G +CK+P +A+Q P + AA VV
Sbjct: 1334 ASSSGLWNNIHCSSY-KGFICKMPKIIDPVTTHSSITTKADQRKMDPQPKGSSKAAGVVT 1392
Query: 1419 LMAVLLLLALLTAALILYRRRQSI---ERGAFEGARYSRSSSSPTEATEKNILVSDMEMN 1475
++ +L+++ AA Y++R ++ + FE Y S+ SP + K+ L+ ++E N
Sbjct: 1393 VV-LLIVIGAGVAAYFFYKKRHALHIPQEATFENTLYFNSNLSPGTSDTKD-LMGNIEQN 1450
Query: 1476 E 1476
E
Sbjct: 1451 E 1451
>ref|NP_032893.1| phospholipase A2, group IB, pancreas, receptor; PLA2-I receptor [Mus
musculus]
pir||S48719 phospholipase-A(2) receptor protein - mouse
dbj|BAA06443.1| (D30779) phospholipase A2 receptor [Mus musculus]
Length = 1487
Score = 889 bits (2273), Expect = 0.0
Identities = 508/1478 (34%), Positives = 774/1478 (51%), Gaps = 92/1478 (6%)
Query: 40 EPNVFLIFSHGLQGCLEAQGGQVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWP 99
+ +F+I S L+ C++A G V C WKWVS + LFN+G CLG
Sbjct: 41 DKGIFIIQSESLKTCIQA-GKSVLTLENCKQPNEHMLWKWVSDDHLFNVGGSGCLGLNIS 99
Query: 100 GTNTTASLGMYECDREALNLRWHC--RTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQ 157
L +YECD ++LRWHC + + L + ++ N T+ Q +
Sbjct: 100 ALEQP--LKLYECDSTLISLRWHCDRKMIEGPLQYKVQVKSDN-----TVVARKQIH--R 150
Query: 158 WRIYGSEE-DLCALPYHEVYTIQGNSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATT 216
W Y S D+C P ++YT++GN+HG PC PF++ W H C G+++ LWCATT
Sbjct: 151 WIAYTSSGGDICEHPSRDLYTLKGNAHGMPCVFPFQFKGHWHHDCIREGQKEHLLWCATT 210
Query: 217 QDYGKDERWGFCPIKSND---CETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADL 273
Y +DE+WGFCP ++ C+ W ++ + CYQFN S+LSW +A +SC QG L
Sbjct: 211 SRYEEDEKWGFCPDPTSMKVFCDATWQRNGSSRICYQFNLLSSLSWNQAHSSCLMQGGAL 270
Query: 274 LSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDNP-SE 332
LSI + E+ +I L+ +WIGLN LD GWQWSD +PL YLNW + P E
Sbjct: 271 LSIADEDEEDFIRKHLSKVVKEVWIGLNQLDEKAGWQWSDGTPLSYLNWSQEITPGPFVE 330
Query: 333 ENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEP-TPPDRWANVKVECEPSWQPFQG 391
+CG + S+ W++RDC LPY+CK+ N TA+ D W C+P W PF
Sbjct: 331 HHCGTLEVVSA-AWRSRDCESTLPYICKRDLNHTAQGILEKDSWKYHATHCDPDWTPFNR 389
Query: 392 HCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQE-VEELWIGLNDLKLQ 450
CY+L+ +++SW + +C L+ + S+AE+EF+ ++ E E WIGL+ K+
Sbjct: 390 KCYKLKKDRKSWLGALHSCQSNDSVLMDVASLAEVEFLVSLLRDENASETWIGLSSNKIP 449
Query: 451 MNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSICKKAGQL 510
++FEWS GS V FT+W+P EP + + CV+ +GRW C + L ICKKAGQ+
Sbjct: 450 VSFEWSSGSSVIFTNWYPLEPRILPNRRQLCVSAEESDGRWKVKDCKERLFYICKKAGQV 509
Query: 511 SQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARR--LCTDHGSQLVTITNRFEQAFV 568
A+E GC GW H CY + ++ EA C+ L+TIT+RFEQAF+
Sbjct: 510 ---PADEQSGCPAGWERHGRFCYKIDTVLRSFEEASSGYYCS---PALLTITSRFEQAFI 563
Query: 569 SSLIYN--WEGEYFWTALQDLNSTGSFFWLS---GDEVMYTHWNRDQPGYSRGGCVALAT 623
+SLI + + YFW ALQD N+TG + W + + V YT+WN QP +RGGCV +
Sbjct: 564 TSLISSVAEKDSYFWIALQDQNNTGEYTWKTVGQREPVQYTYWNTRQPS-NRGGCVVVRG 622
Query: 624 GSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCY 683
GS++G WEVK+C+ F+A +C+ + EL P C W S T L C+
Sbjct: 623 GSSLGRWEVKDCSDFKAMSLCKTPVKIWEKTELEERWP----FHPCYMDWESATGLASCF 678
Query: 684 KVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHW 743
KVF SE++ K+SW +A+ C+E GA L S A EEE+FV +L+ F + ++
Sbjct: 679 KVFHSEKVLMKRSWREAEAFCEEFGAHLASFAHIEEENFVNELLHSKFNWT-----QERQ 733
Query: 744 FWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRGCAVLDLASLQWVAMQCDTQ 803
FWIG NRR+P SW WSDG +F + + ++D + CAV A+ + C ++
Sbjct: 734 FWIGFNRRNPLNAGSWAWSDGSPV-VSSFLDNAYFEEDAKNCAVYK-ANKTLLPSNCASK 791
Query: 804 LDWICKIPRGTDVREPD----DSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAE 859
+WIC+IPR + PD D+P WL +Q AEY F H + WA + +C W +++
Sbjct: 792 HEWICRIPRDVRPKFPDWYQYDAP-----WLFYQNAEYLFHTHPAEWATFEFVCGWLRSD 846
Query: 860 LTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR 919
+++S E +F+ ++ ++ + WWIGL + + +W++GS + F +W G+
Sbjct: 847 FLTIYSAQEQEFIHSKIKGLTKYGVK-WWIGLEEGGARDQIQWSNGSPVIFQNWDKGREE 905
Query: 920 PV-GKDKKCVYMTASREDWGDQRCLTALPYICKRSN--VTKETQPPDLPTTALGGCPSDW 976
V + K+CV++++ WG + C LP ICKR V ++ +PP P G CP W
Sbjct: 906 RVDSQRKRCVFISSITGLWGTENCSVPLPSICKRVKIWVIEKEKPPTQP----GTCPKGW 961
Query: 977 IQFLNKCFQVQ-GQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLW 1035
+ F KCF V ++P+ W+ AQ C + LV+I + LEQAFIT +L T ++W
Sbjct: 962 LYFNYKCFLVTIPKDPRELKTWTGAQEFCVAKGGTLVSIKSELEQAFITMNLFGQTTNVW 1021
Query: 1036 IGLHASQRDFQWVEQEPLMYANWAPGE----PSGPSPAPSGNKPTSCAVVLHSPSAHFTG 1091
IGL ++ + +WV +PL+Y+NW+P + PS + + P CA++ +P+ HFTG
Sbjct: 1022 IGLQSTNHE-KWVNGKPLVYSNWSPSDIINIPSYNTTEFQKHIPL-CALMSSNPNFHFTG 1079
Query: 1092 RWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLLQKPLRWHDALL 1151
+W C +E +GF+C+K D + A + L Y N T+++++ + W+ A
Sbjct: 1080 KWYFDDCGKEGYGFVCEKMQDTLEHHVNVSDTSAIPSTLEYGNRTYKIIRGNMTWYAAGK 1139
Query: 1152 LCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQD 1211
C H A LA +PD + QAFLT L WIGL+ + + + W + W+D
Sbjct: 1140 SCRMHRAELASIPDAFHQAFLTVLLSRLGHTHWIGLSTTDNGQTFDWSDGTKSPFTYWKD 1199
Query: 1212 GEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGSCPQGLADSAWI 1271
E G C + D +G W +T+C++ LQGA+C V + + + G C + WI
Sbjct: 1200 EESAFLGDCAFADTNGRWHSTACESFLQGAICHVVT---ETKAFEHPGLCSE--TSVPWI 1254
Query: 1272 PFREHCYSFHMEL-LLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSRGAWL 1330
F+ +CYSF L ++A + C+ G +L+I D EN F+ E L ++ + WL
Sbjct: 1255 KFKGNCYSFSTVLDSRSFEDAHEFCKSEGSNLLAIRDAAENSFLLEELLAFGSSVQMVWL 1314
Query: 1331 GMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGACTNITMG 1390
F+ TL W D T SNWG L + C ++ G+W C + G
Sbjct: 1315 NAQFDNNNKTLRWFDGTPTEQSNWGLRKPDMDHLKPHPCVVLRIPEGIWHFTPCED-KKG 1373
Query: 1391 VVCKLPRAEQSSFSPSALPE----NPAALVVVLMAVLLLLALLTAALILYRRRQSIERGA 1446
+CK+ E + +A PE + V V + +++ L + +Y+++ I
Sbjct: 1374 FICKM---EAGIPAVTAQPEKGLSHSIVPVTVTLTLIIALGIFMLCFWIYKQKSDI---- 1426
Query: 1447 FEGARYSRSSSSP-----TEATEKNILVSDMEMNEQQE 1479
F+ SR S P T E+NIL+SD+E N E
Sbjct: 1427 FQRLTGSRGSYYPTLNFSTAHLEENILISDLEKNTNDE 1464
>ref|NP_002429.1| mannose receptor, C type 1 [Homo sapiens]
sp|P22897|MANR_HUMAN MACROPHAGE MANNOSE RECEPTOR PRECURSOR
pir||A36563 mannose receptor precursor - human
gb|AAA60389.1| (M93221) mannose receptor [Homo sapiens]
gb|AAA59868.1| (J05550) mannose receptor precursor [Homo sapiens]
Length = 1456
Score = 887 bits (2267), Expect = 0.0
Identities = 496/1481 (33%), Positives = 771/1481 (51%), Gaps = 79/1481 (5%)
Query: 33 PGDAALPEPNVFLIFSHGLQGCLEAQGGQVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQ 92
PG L + FLI++ + C++A T ACN +Q+++WVS +++ ++
Sbjct: 14 PGAVLLLDTRQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFKL 73
Query: 93 CLGTGWPGTNTTASLGMYECDREALNLRWHCRT------LGDQLSLLLGARTSNISKPGT 146
CLG P ++ +Y CD ++ +W C+ G+ L G R K
Sbjct: 74 CLGV--PSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNRQE---KNIM 128
Query: 147 LERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQGNSHGKPCTIPFKYDNQWFHGCTSTGR 206
L +G S +W+IYG+ ++LC+ Y +YT+ GN++G C PFK++N+W+ CTS GR
Sbjct: 129 LYKGSGLWS-RWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYADCTSAGR 187
Query: 207 EDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASC 266
DG LWC TT DY D+ +G+CP+K E+ W+KD LT YQ N +S L+W +A SC
Sbjct: 188 SDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQINSKSALTWHQARKSC 247
Query: 267 EQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQ 326
+QQ A+LLSITEIHEQTY+ GL + +S LWIGLN L + GWQWSD SP +YLNW
Sbjct: 248 QQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGS 307
Query: 327 PDNPSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPSW 386
P ++C + + W+N +C L Y+C KK N T ++V C W
Sbjct: 308 PSAEPGKSCVSLNPGKNAKWENLECVQKLGYIC-KKGNTTLNSFVIPSESDVPTHCPSQW 366
Query: 387 QPFQGHCYRL-QAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEV-EELWIGL 444
P+ GHCY++ + EK+ +++ C + GGDL SIH++ EL+FI Q+ E +ELWIGL
Sbjct: 367 WPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDELWIGL 426
Query: 445 NDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSIC 504
ND+K+QM FEWSDG+ V+FT W EP++ + EDCV + G +G W D C L IC
Sbjct: 427 NDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRGCEWPLGYIC 486
Query: 505 KKAGQLSQG--AAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNR 562
K + SQG E + GCRKGW H CY +G T++EA + C + + L TI +R
Sbjct: 487 KMKSR-SQGPEIVEVEKGCRKGWKKHHFYCYMIGHTLSTFAEANQTCNNENAYLTTIEDR 545
Query: 563 FEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQPGYSRGGCVALA 622
+EQAF++S + +YFWT L D+ + G+F W +EV +THWN D PG + GCVA+
Sbjct: 546 YEQAFLTSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTHWNSDMPG-RKPGCVAMR 604
Query: 623 TGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYC 682
TG A GLW+V C +A+++C+ P P P P CP+ W + ++ C
Sbjct: 605 TGIAGGLWDVLKCDE-KAKFVCKHWAEGVTHPPKPTTTPEP----KCPEDWGASSRTSLC 659
Query: 683 YKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQH 742
+K+++ + +KK+W +++ C+ LG L S+ + EE+ + ++ + H+
Sbjct: 660 FKLYAKGK-HEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLIT-----ASGSYHK-- 711
Query: 743 WFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDD-DDIRGCAVL-DLASLQWVAMQC 800
FW+GL P G + WSDG SY N+ ++ ++ C L ++ W + C
Sbjct: 712 LFWLGLTYGSPSEG--FTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINC 769
Query: 801 DTQLDWICKIPRG-TDVREPDDSPQGRRE-----WLRFQEAEYKFFEHHSTWAQAQRICT 854
+ +WIC+I +G T EP +PQ W+ +++ +Y F + T A+ C
Sbjct: 770 EHLNNWICQIQKGQTPKPEPTPAPQDNPPVTEDGWVIYKDYQYYFSKEKETMDNARAFCK 829
Query: 855 WFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWA 914
+L S+ S++E FL + + + ++IGL S D +F W DGS ++++SWA
Sbjct: 830 RNFGDLVSIQSESEKKFLWKYVNR--NDAQSAYFIGLLIS-LDKKFAWMDGSKVDYVSWA 886
Query: 915 PGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKR--SNVTKETQPPDLPTTALGGC 972
G+P +D+ CV M ++ W D C +IC+R S++ T P +P+ GC
Sbjct: 887 TGEPNFANEDENCVTMYSNSGFWNDINCGYPNAFICQRHNSSINATTVMPTMPSVP-SGC 945
Query: 973 PSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTF 1032
W + NKCF++ G + R W EA+ +C LV+I N EQAF+T + + TF
Sbjct: 946 KEGWNFYSNKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTF 1005
Query: 1033 DLWIGLH--ASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFT 1090
W GL+ S+ F W + + Y NW G P G + S + C V++ S +
Sbjct: 1006 SAWTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLS-YEDADCVVIIGGAS-NEA 1063
Query: 1091 GRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLLQKPLRWHDAL 1150
G+W D +C + G+ICQ +DPSL+ PA + + Y ++ L+++ +WH+A
Sbjct: 1064 GKWMDDTC-DSKRGYICQTRSDPSLTNPPATI--QTDGFVKYGKSSYSLMRQKFQWHEAE 1120
Query: 1151 LLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQ 1210
C+ HN+ +A + DPY+ AF +WI L +Y+W + + Y W
Sbjct: 1121 TYCKLHNSLIASILDPYSNAFAWLQMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWA 1180
Query: 1211 DGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGSCPQGLADSAW 1270
EP+ C Y+D+DG W+T C+ +C S P G CP+ +AW
Sbjct: 1181 ADEPKLKSACVYLDLDGYWKTAHCNESFY-FLCKRSDEIPATEPPQLPGRCPES-DHTAW 1238
Query: 1271 IPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSRGAWL 1330
IPF HCY +A C R G +++SI E+ F+ ++ + ++ W+
Sbjct: 1239 IPFHGHCYYIESSYTRNWGQASLECLRMGSSLVSIESAAESSFLSYRVEPLKSKT-NFWI 1297
Query: 1331 GMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGACTNITMG 1390
G+ F GT +W +N+ V++ NW G N C + ++SG W C++ G
Sbjct: 1298 GL-FRNVEGTWLWINNSPVSFVNW---NTGDPSGERNDCVALHASSGFWSNIHCSSY-KG 1352
Query: 1391 VVCKLP--------------RAEQSSFSPSALPENPAALVVVLMAVLLLLALLTAALILY 1436
+CK P +A+ PS N A +V++++ ++L A L A
Sbjct: 1353 YICKRPKIIDAKPTHELLTTKADTRKMDPSKPSSNVAGVVIIVILLILTGAGLAAYFFYK 1412
Query: 1437 RRRQSI-ERGAFEGARYSRSSSSPTEATEKNILVSDMEMNE 1476
+RR + + GAFE Y S SSP + K+ LV ++E NE
Sbjct: 1413 KRRVHLPQEGAFENTLYFNSQSSPGTSDMKD-LVGNIEQNE 1452
>ref|XP_002318.1| phospholipase A2 receptor 1, 180kD [Homo sapiens]
Length = 1324
Score = 869 bits (2220), Expect = 0.0
Identities = 483/1358 (35%), Positives = 716/1358 (52%), Gaps = 85/1358 (6%)
Query: 19 VLLLGCLHLGRPGAPGDAALPEPN---------VFLIFSHGLQGCLEAQGGQVRVTPACN 69
+LLL L R A G AA P +F+I S L+ C++A G V C
Sbjct: 7 LLLLLLLGAPRGCAEGVAAALTPERLLEWQDKGIFVIQSESLKKCIQA-GKSVLTLENCK 65
Query: 70 TSLPAQRWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLRWHCR----T 125
+ WKWVS + LFN+G CLG + SL YECD ++LRW C T
Sbjct: 66 QANKHMLWKWVSNHGLFNIGGSGCLGLNFSAPEQPLSL--YECDSTLVSLRWRCNRKMIT 123
Query: 126 LGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEE-DLCALPYHEVYTIQGNSHG 184
Q S+ + + ++ + + W YGS D+C + +++TI+GN+HG
Sbjct: 124 GPLQYSVQVAHDNTVVASRKYIHK--------WISYGSGGGDICEYLHKDLHTIKGNTHG 175
Query: 185 KPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSN---DCETFWDK 241
PC PF+Y++QW H CT GRED LWCATT Y +DE+WGFCP ++ C+T W+K
Sbjct: 176 MPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPTSAEVGCDTIWEK 235
Query: 242 DQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLN 301
D + CYQFN S+LSW EA +SC+ QG LLSIT+ E+ +I+ ++ + +W+GLN
Sbjct: 236 DLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFISEHMSSKTVEVWMGLN 295
Query: 302 DLDTSGGWQWSDNSPLKYLNWESDQPDNP-SEENCGVIRTESSGGWQNRDCSIALPYVCK 360
LD GWQWSD +PL YLNW + P E++CG + W++RDC LPY+CK
Sbjct: 296 QLDEHAGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICK 355
Query: 361 KKPN-ATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVS 419
K N E D W CEP W P+ +CY+LQ E+++W E+ ++C L+
Sbjct: 356 KYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALID 415
Query: 420 IHSMAELEFITKQIKQE-VEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSL 478
I S+AE+EF+ + E E WIGL+ K+ ++FEWS+ S V FT+WH EP+ F +
Sbjct: 416 ITSLAEVEFLVTLLGDENASETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRS 475
Query: 479 EDCVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGED 538
+ CV+ EG W C + L ICKKAG + ++ + GC++GW H CY +
Sbjct: 476 QLCVSAEQSEGHWKVKNCEERLFYICKKAGHV---LSDAESGCQEGWERHGGFCYKIDTV 532
Query: 539 QVTYSEARR--LCTDHGSQLVTITNRFEQAFVSSLI---YNWEGEYFWTALQDLNSTGSF 593
++ +A C LVTITNRFEQAF++SLI + YFW ALQD N TG +
Sbjct: 533 LRSFDQASSGYYCP---PALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEY 589
Query: 594 FW----LSGDEVMYTHWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLG 649
W + V YTHWN GYS GGCVA+ +G WEVK+C F+A +C+Q +
Sbjct: 590 TWKPVGQKPEPVQYTHWNTHHLGYS-GGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVE 648
Query: 650 TPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGA 709
E P C W S+ L C+KVF SE++ K++W +A+ C+E GA
Sbjct: 649 NQEKAEYEERWP----FHPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGA 704
Query: 710 QLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSY 769
L S A EEE+FV +L+ F + E+ FWIG N+R+P SW WSD
Sbjct: 705 HLASFAHIEEENFVNELLHSKFNWT-----EERQFWIGFNKRNPLNAGSWEWSDRTPV-V 758
Query: 770 HNFDRSRHDDDDIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREP----DDSPQG 825
+F + + +D R CAV A+ + + C ++ +WICKIPR + P D P
Sbjct: 759 SSFLDNTYFGEDARNCAVYK-ANKTLLPLHCGSKREWICKIPRDVKPKIPFWYQYDVP-- 815
Query: 826 RREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQ 885
WL +Q+AEY F S W + +C+W ++L ++HS E +F+ ++ S+
Sbjct: 816 ---WLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSK-YGA 871
Query: 886 HWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPV-GKDKKCVYMTASREDWGDQRCLT 944
WWIGL ++ FRW DG+ + + +W G+ R V + ++C ++++ WG + C
Sbjct: 872 SWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEECSV 931
Query: 945 ALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQ-GQEPQSRVKWSEAQFS 1003
++P ICKR V + D P G CP W+ F KC + ++P S W+ AQ
Sbjct: 932 SMPSICKRKKVWLIEKKKDTPKQH-GTCPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHF 990
Query: 1004 CEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLHASQRDFQWVEQEPLMYANWAPGE- 1062
C ++ LV I + +EQAFIT +L T +WIGL + W+ +P++Y+NW+P +
Sbjct: 991 CAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGLQNDDYE-TWLNGKPVVYSNWSPFDI 1049
Query: 1063 ---PSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPS-LSPS 1118
PS + + P CA++ +P+ HFTG+W C +E +GF+C+K D S +
Sbjct: 1050 INIPSHNTTEVQKHIPL-CALLSSNPNFHFTGKWYFEDCGKEGYGFVCEKMQDTSGHGVN 1108
Query: 1119 PAALPPAPGTELSYLNGTFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARG 1178
+ + P P T L Y N T++++ + W+ A+ C H A L + D Y Q+FLT
Sbjct: 1109 TSDMYPMPNT-LEYGNRTYKIINANMTWYAAIKTCLMHKAQLVSITDQYHQSFLTVVLNR 1167
Query: 1179 LRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKL 1238
L WIGL + + W ++ W+D E G C + D +G W +T+C++ L
Sbjct: 1168 LGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKDEESSLLGDCVFADSNGRWHSTACESFL 1227
Query: 1239 QGAVCGVSSGPPPPRRISYHGSCPQGLADSAWIPFREHCYSFHMEL-LLGHKEARQRCQR 1297
QGA+C V PP R+ + C + WI F+ +CYSF L + + A + C++
Sbjct: 1228 QGAICHV---PPETRQSEHPELCSE--TSIPWIKFKSNCYSFSTVLDSMSFEAAHEFCKK 1282
Query: 1298 AGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFN 1335
G +L+I DE EN F+ E L ++ + WL F+
Sbjct: 1283 EGSNLLTIKDEAENAFLLEELFAFGSSVQMVWLNAQFD 1320
Score = 218 bits (550), Expect = 3e-55
Identities = 255/1139 (22%), Positives = 438/1139 (38%), Gaps = 172/1139 (15%)
Query: 351 CSIALPYVCKKKPNATAEPTPPDRWANVKVECEPSWQP-FQGH-CYRLQA-EKRSWQESK 407
C+ Y +K +PT + +V C+ W+ H CY+ SW E+
Sbjct: 204 CATTSRYERDEKWGFCPDPT------SAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAH 257
Query: 408 KACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWH 467
+C GG L+SI E FI++ + + E+W+GLN L ++WSDG+ +++ +W
Sbjct: 258 SSCQMQGGTLLSITDETEENFISEHMSSKTVEVWMGLNQLDEHAGWQWSDGTPLNYLNWS 317
Query: 468 PFEPNNFRDSLED-CVTIWG-PEGRWNDSPCNQSLPSICKK-AGQLSQGAAEEDHG---- 520
P NF +ED C T W C +LP ICKK + E+D
Sbjct: 318 P--EVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYA 375
Query: 521 --CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGE 578
C GW ++ +CY L +++ T+ EA R C S L+ IT+ E F+ +L+ +
Sbjct: 376 THCEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENAS 435
Query: 579 YFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG-YSRGGCVALATGSAMGLWEVKNCTS 637
W L SF W + V++T+W+ +P + + ++ + G W+VKNC
Sbjct: 436 ETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEE 495
Query: 638 FRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSW 697
R YIC+++ G ++ G C +GW + +CYK+ + R D+ S
Sbjct: 496 -RLFYICKKA-GHVLSDAESG----------CQEGW--ERHGGFCYKIDTVLRSFDQAS- 540
Query: 698 VQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQ 757
+ L+++ + E+ F+ ++++ + + +FWI L ++ G
Sbjct: 541 -----SGYYCPPALVTITNRFEQAFITSLISSVVKMKDS------YFWIALQDQNDTGEY 589
Query: 758 SWR----WSDGVGFSYHNFD-----------RSRHDDD--DIRGCAVLDLASLQWVAMQC 800
+W+ + V +++ N R RH +++ C SL ++
Sbjct: 590 TWKPVGQKPEPVQYTHWNTHHLGYSGGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVEN 649
Query: 801 DTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAEL 860
+ ++ + P + + P G + +E + TW +A+ C F A L
Sbjct: 650 QEKAEYEERWPFHPCYLDWESEP-GLASCFKVFHSEKVLMKR--TWREAEAFCEEFGAHL 706
Query: 861 TSVHSQAELDFLSHNLQ-KFSRAQEQHWWIGLHTSE--SDGRFRWTDGS--IINFISWAP 915
S E +F++ L KF+ +E+ +WIG + + G + W+D + + +F+
Sbjct: 707 ASFAHIEEENFVNELLHSKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLD--- 763
Query: 916 GKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSD 975
G+D + + + + C + +ICK K P +P P
Sbjct: 764 --NTYFGEDARNCAVYKANKTLLPLHCGSKREWICKIPRDVK----PKIPFWYQYDVPWL 817
Query: 976 WIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT---F 1032
+ Q F E W +F C + L+TI + EQ FI + + ++
Sbjct: 818 FYQDAEYLFHTFASE------WLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGA 871
Query: 1033 DLWIGLHASQR--DFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFT 1090
WIGL + +F+W + P++Y NW G + N+ C + + T
Sbjct: 872 SWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVN-----NQSQRCGFI-----SSIT 921
Query: 1091 GRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGT---ELSYLNGTFRLLQKPL--- 1144
G W C+ IC++ L P GT Y N LL P
Sbjct: 922 GLWGSEECSVSMPS-ICKR-KKVWLIEKKKDTPKQHGTCPKGWLYFNYKCLLLNIPKDPS 979
Query: 1145 ---RWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSE 1201
W A C +L + QAF+T G T +WIGL ++ +W++
Sbjct: 980 SWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGLQNDDYE---TWLNG 1036
Query: 1202 EPLNYVGWQDGEPQQPGGCTYVDVD------------------GAWRTTSCDTKLQGAVC 1243
+P+ Y W + +V G W C + G VC
Sbjct: 1037 KPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTGKWYFEDCGKEGYGFVC 1096
Query: 1244 ---------GVSSGP--PPPRRISYHGSCPQGL-ADSAWIPFREHCYSFHMELLLGHKEA 1291
GV++ P P + Y + + A+ W + C L HK
Sbjct: 1097 EKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIKTC--------LMHK-- 1146
Query: 1292 RQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNY 1351
++SI D+ F+ L W+G+ G W D T ++
Sbjct: 1147 --------AQLVSITDQYHQSFLTVVLNRL---GYAHWIGLFTTDNGLNFDWSDGTKSSF 1195
Query: 1352 SNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGACTNITMGVVCKLPRAEQSSFSPSALPE 1410
+ W S+L C + SN G W AC + G +C +P + S P E
Sbjct: 1196 TFWKDEE--SSLLG--DCVFADSN-GRWHSTACESFLQGAICHVPPETRQSEHPELCSE 1249
Score = 151 bits (377), Expect = 7e-35
Identities = 175/785 (22%), Positives = 280/785 (35%), Gaps = 115/785 (14%)
Query: 659 PDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYE 718
PDPT + G C W D CY+ L SW +A +CQ G LLS+
Sbjct: 220 PDPTSAEVG-CDTIWEKDLNSHICYQF----NLLSSLSWSEAHSSCQMQGGTLLSITDET 274
Query: 719 EEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHD 778
EE+F++ ++ E W+GLN+ D G W+WSDG +Y N+ +
Sbjct: 275 EENFISEHMSSKTVE----------VWMGLNQLDEHAG--WQWSDGTPLNYLNWSPEVNF 322
Query: 779 DDDIRG-CAVLD-LASLQWVAMQCDTQLDWICKIPRGT---DVREPDD----SPQGRREW 829
+ + C W + C++ L +ICK ++ E D + W
Sbjct: 323 EPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGW 382
Query: 830 LRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWI 889
+ YK + TW +A R C + L + S AE++FL L + ++ WI
Sbjct: 383 NPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASET---WI 439
Query: 890 GLHTSESDGRFRWTDGSIINFISWAPGKPRPV-GKDKKCVYMTASREDWGDQRCLTALPY 948
GL +++ F W++ S + F +W +P + + CV S W + C L Y
Sbjct: 440 GLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFY 499
Query: 949 ICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQE 1008
ICK++ + + A GC W + C+++ + ++ + S
Sbjct: 500 ICKKAG--------HVLSDAESGCQEGWERHGGFCYKID-----TVLRSFDQASSGYYCP 546
Query: 1009 AQLVTITNPLEQAFITASLPNVT----FDLWIGLHASQR--DFQWV----EQEPLMYANW 1058
LVTITN EQAFIT+ + +V WI L ++ W + EP+ Y +W
Sbjct: 547 PALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHW 606
Query: 1059 APGEP--SGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLS 1116
SG A G P GRW+ + C +C++ +
Sbjct: 607 NTHHLGYSGGCVAMRGRHPL--------------GRWEVKHCRHFKAMSLCKQPVENQEK 652
Query: 1117 PSPAALPPAPGTELSY-----LNGTFRLL--QKPLR---WHDALLLCESHNASLAYVPDP 1166
P L + L F++ +K L W +A CE A LA
Sbjct: 653 AEYEERWPFHPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHI 712
Query: 1167 YTQAFLTQAARGL-----RTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEP------- 1214
+ F+ + WIG SW W D P
Sbjct: 713 EEENFVNELLHSKFNWTEERQFWIGFNKRNPLNAGSWE---------WSDRTPVVSSFLD 763
Query: 1215 -----QQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGSCPQGLADSA 1269
+ C + C +K + +C + P Y P
Sbjct: 764 NTYFGEDARNCAVYKANKTLLPLHCGSKREW-ICKIPRDVKPKIPFWYQYDVP------- 815
Query: 1270 WIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSRGAW 1329
W+ +++ Y FH C +L+I E F+ +++ W
Sbjct: 816 WLFYQDAEYLFHT-FASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWW 874
Query: 1330 LGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGACTNITM 1389
+G+ W+D T V Y NW C +I S +GLW C +++M
Sbjct: 875 IGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEEC-SVSM 933
Query: 1390 GVVCK 1394
+CK
Sbjct: 934 PSICK 938
Score = 133 bits (332), Expect = 1e-29
Identities = 200/934 (21%), Positives = 347/934 (36%), Gaps = 123/934 (13%)
Query: 520 GCRKGWT--WHSPSCYWLGE-DQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWE 576
GC W +S CY +++SEA C G L++IT+ E+ F+S + +
Sbjct: 228 GCDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFISEHMSSKT 287
Query: 577 GEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRD---QPGYSRGGCVALATGSAMGLWEVK 633
E W L L+ + W G + Y +W+ + +P + C ++ W +
Sbjct: 288 VEV-WMGLNQLDEHAGWQWSDGTPLNYLNWSPEVNFEP-FVEDHCGTFSSFMPSA-WRSR 344
Query: 634 NCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQD 693
+C S YIC++ L + E+ D C GW + R CYK+ E
Sbjct: 345 DCES-TLPYICKKYLNH-IDHEIVEKDAWKYYATHCEPGW--NPYNRNCYKLQKEE---- 396
Query: 694 KKSWVQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDP 753
K+W +A +CQ + L+ + S E F+ +L E+ E WIGL+
Sbjct: 397 -KTWHEALRSCQADNSALIDITSLAEVEFLVTLLGD---ENASET------WIGLSSN-- 444
Query: 754 RGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--CAVLDLASLQWVAMQCDTQLDWICKIP 811
+ S+ WS+ + N+ R C + + W C+ +L +ICK
Sbjct: 445 KIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFYICK-- 502
Query: 812 RGTDVREPDDSPQGRRE-WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELD 870
+ V D+ G +E W R YK ++ QA + L ++ ++ E
Sbjct: 503 KAGHVLS--DAESGCQEGWERHGGFCYKIDTVLRSFDQASS-GYYCPPALVTITNRFEQA 559
Query: 871 FLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTD-GSIINFISWAPGKPRPVGKDKKCVY 929
F++ + + ++ ++WI L G + W G + + +G CV
Sbjct: 560 FITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHHLGYSGGCVA 619
Query: 930 MTASRE--DWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQF--LNKCFQ 985
M W + C + V + + C DW L CF+
Sbjct: 620 MRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWPFHPCYLDWESEPGLASCFK 679
Query: 986 V-QGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLP---NVTFD--LWIGLH 1039
V ++ + W EA+ CE+ A L + + E+ F+ L N T + WIG +
Sbjct: 680 VFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHSKFNWTEERQFWIGFN 739
Query: 1040 A----SQRDFQWVEQEPLMYA---NWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGR 1092
+ ++W ++ P++ + N GE + NK + LH S
Sbjct: 740 KRNPLNAGSWEWSDRTPVVSSFLDNTYFGEDARNCAVYKANKTL---LPLHCGSKR---E 793
Query: 1093 WDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLLQKPLRWHDALLL 1152
W IC+ D + P L Y + + W + +
Sbjct: 794 W------------ICKIPRD--VKPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFEFV 839
Query: 1153 CESHNASLAYVPDPYTQAFLTQAARGLR---TPLWIGLAGEEGSRRYSWVSEEPLNYVGW 1209
C ++ L + + Q F+ + L WIGL E + + W P+ Y W
Sbjct: 840 CSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNW 899
Query: 1210 QDGEPQ----QPGGCTYVD-VDGAWRTTSCDTKLQGAVCG------VSSGPPPPRRISYH 1258
G + Q C ++ + G W + C + ++C + P++ H
Sbjct: 900 DTGRERTVNNQSQRCGFISSITGLWGSEECSVSMP-SICKRKKVWLIEKKKDTPKQ---H 955
Query: 1259 GSCPQGLADSAWIPFREHCYSFHM----ELLLGHKEARQRCQRAGGAVLSILDEMENVFV 1314
G+CP+G W+ F C ++ A+ C GG +++I E+E F+
Sbjct: 956 GTCPKG-----WLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFI 1010
Query: 1315 WEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNS------ 1368
+L GQ+ W+G+ + W + V YSNW P + ++ SHN+
Sbjct: 1011 TMNLF---GQTTSVWIGLQNDDYE---TWLNGKPVVYSNWSPFDI-INIPSHNTTEVQKH 1063
Query: 1369 ---CYWIQSN-----SGLWRPGACTNITMGVVCK 1394
C + SN +G W C G VC+
Sbjct: 1064 IPLCALLSSNPNFHFTGKWYFEDCGKEGYGFVCE 1097
>ref|NP_031392.1| phospholipase A2 receptor 1, 180kD [Homo sapiens]
pir||B56395 secretory phospholipase A2 receptor precursor, soluble form - human
gb|AAC50163.1| (U17034) putative soluble PLA2 receptor precursor [Homo sapiens]
Length = 1326
Score = 860 bits (2199), Expect = 0.0
Identities = 473/1331 (35%), Positives = 706/1331 (52%), Gaps = 80/1331 (6%)
Query: 40 EPNVFLIFSHGLQGCLEAQGGQVRVTPACNTSLPAQR---WKWVSRNRLFNLGTMQCLGT 96
+ +F+I S L+ C++A G+ +T S A + WKWVS + LFN+G CLG
Sbjct: 37 DKGIFVIQSESLKKCIQA--GKSVLTLGRTGSKQANKHMLWKWVSNHGLFNIGGSGCLGL 94
Query: 97 GWPGTNTTASLGMYECDREALNLRWHCR----TLGDQLSLLLGARTSNISKPGTLERGDQ 152
+ SL YECD ++LRW C T Q S+ + + ++ + +
Sbjct: 95 NFSAPEQPLSL--YECDSTLVSLRWRCNRKMITGPLQYSVQVAHDNTVVASRKYIHK--- 149
Query: 153 TRSGQWRIYGSEE-DLCALPYHEVYTIQGNSHGKPCTIPFKYDNQWFHGCTSTGREDGHL 211
W YGS D+C + +++TI+GN+HG PC PF+Y++QW H CT GRED L
Sbjct: 150 -----WISYGSGGGDICEYLHKDLHTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLL 204
Query: 212 WCATTQDYGKDERWGFCPIKSN---DCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQ 268
WCATT Y +DE+WGFCP ++ C+T W+KD + CYQFN S+LSW EA +SC+
Sbjct: 205 WCATTSRYERDEKWGFCPDPTSAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQM 264
Query: 269 QGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPD 328
QG LLSIT+ E+ +I ++ + +W+GLN LD GWQWSD +PL YLNW +
Sbjct: 265 QGGTLLSITDETEENFIREHMSSKTVEVWVGLNQLDEDAGWQWSDGTPLNYLNWSPEVNF 324
Query: 329 NP-SEENCGVIRTESSGGWQNRDCSIALPYVCKKKPN-ATAEPTPPDRWANVKVECEPSW 386
P E++CG + W++RDC LPY+CKK N E D W CEP W
Sbjct: 325 EPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGW 384
Query: 387 QPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQE-VEELWIGLN 445
P+ +CY+LQ E+++W E+ ++C L+ I S+AE+EF+ + E E WIGL+
Sbjct: 385 NPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASETWIGLS 444
Query: 446 DLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSICK 505
K+ ++FEWS+ S V FT+WH EP+ F + + CV+ EG W C + L ICK
Sbjct: 445 SNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFYICK 504
Query: 506 KAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARR--LCTDHGSQLVTITNRF 563
KAG + ++ + GC++GW CY + ++ +A C LVTITNRF
Sbjct: 505 KAGHV---LSDAESGCQEGWEETCGFCYKIDTVLRSFDQASSGYYCP---PALVTITNRF 558
Query: 564 EQAFVSSLI---YNWEGEYFWTALQDLNSTGSFFW----LSGDEVMYTHWNRDQPGYSRG 616
EQAF++SLI + YFW ALQD N TG + W + V YTHWN QP YS G
Sbjct: 559 EQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYS-G 617
Query: 617 GCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASD 676
GCVA+ +G WEVK+C F+A +C+Q + E P C W S+
Sbjct: 618 GCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWP----FHPCYLDWESE 673
Query: 677 TKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEP 736
L C+KVF SE++ K++W +A+ C+E GA L S A EEE+FV +L+ F +
Sbjct: 674 PGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHPKFNWT-- 731
Query: 737 EIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRGCAVLDLASLQWV 796
E+ FWIG N+R+P SW WSD +F + + +D R CAV + +
Sbjct: 732 ---EERQFWIGFNKRNPLNAGSWEWSDRTPV-VSSFLDNTYFGEDARNCAVYK-PNKTLL 786
Query: 797 AMQCDTQLDWICKIPRGTDVREP----DDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRI 852
+ C ++ +WICKIPR + P D P WL +Q+AEY F S W + +
Sbjct: 787 PLHCGSKREWICKIPRDVKPKIPFWYQYDVP-----WLFYQDAEYLFHTFASEWLNFEFV 841
Query: 853 CTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFIS 912
C+W ++L ++HS E +F+ ++ S+ WWIGL ++ FRW DG+ + + +
Sbjct: 842 CSWLHSDLLTIHSAHEQEFIHSKIKALSK-YGASWWIGLQEERANDEFRWRDGTPVIYQN 900
Query: 913 WAPGKPRPV-GKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGG 971
W G+ R V + ++C ++++ WG + C ++P ICKR V + D P G
Sbjct: 901 WDTGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQH-GT 959
Query: 972 CPSDWIQFLNKCFQVQ-GQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNV 1030
CP W+ F KC + ++P S W+ AQ C ++ LV I + +EQAFIT +L
Sbjct: 960 CPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQ 1019
Query: 1031 TFDLWIGLHASQRDFQWVEQEPLMYANWAPGE----PSGPSPAPSGNKPTSCAVVLHSPS 1086
T +WIGL + W+ +P++Y+NW+P + PS + + P CA++ +P+
Sbjct: 1020 TTSVWIGLQNDDYE-TWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPL-CALLSSNPN 1077
Query: 1087 AHFTGRWDDRSCTEETHGFICQKGTDPS-LSPSPAALPPAPGTELSYLNGTFRLLQKPLR 1145
HFTG+W C +E +GF+C+K D S + + + P P T L Y N T++++ +
Sbjct: 1078 FHFTGKWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNT-LEYGNRTYKIINANMT 1136
Query: 1146 WHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLN 1205
W+ A+ C H A L + D Y Q+FLT L WIGL + + W +
Sbjct: 1137 WYAAIKTCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSS 1196
Query: 1206 YVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGSCPQGL 1265
+ W+D E G C + D +G W +T+CD+ LQGA+C V PP R+ + C +
Sbjct: 1197 FTFWKDEESSLLGDCVFADSNGRWHSTACDSFLQGAICHV---PPETRQSEHPELCSE-- 1251
Query: 1266 ADSAWIPFREHCYSFHMEL-LLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQ 1324
WI F+ +CY F L + + A + C++ G +L+I DE EN F+ E L ++
Sbjct: 1252 TSIPWIKFKSNCYKFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENAFLLEELFAFGSS 1311
Query: 1325 SRGAWLGMNFN 1335
+ WL F+
Sbjct: 1312 VQMVWLNAQFD 1322
Score = 221 bits (557), Expect = 5e-56
Identities = 258/1140 (22%), Positives = 435/1140 (37%), Gaps = 174/1140 (15%)
Query: 351 CSIALPYVCKKKPNATAEPTPPDRWANVKVECEPSWQP-FQGH-CYRLQA-EKRSWQESK 407
C+ Y +K +PT + +V C+ W+ H CY+ SW E+
Sbjct: 206 CATTSRYERDEKWGFCPDPT------SAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAH 259
Query: 408 KACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWH 467
+C GG L+SI E FI + + + E+W+GLN L ++WSDG+ +++ +W
Sbjct: 260 SSCQMQGGTLLSITDETEENFIREHMSSKTVEVWVGLNQLDEDAGWQWSDGTPLNYLNWS 319
Query: 468 PFEPNNFRDSLED-CVTIWG-PEGRWNDSPCNQSLPSICKK-AGQLSQGAAEEDHG---- 520
P NF +ED C T W C +LP ICKK + E+D
Sbjct: 320 P--EVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYA 377
Query: 521 --CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGE 578
C GW ++ +CY L +++ T+ EA R C S L+ IT+ E F+ +L+ +
Sbjct: 378 THCEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENAS 437
Query: 579 YFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG-YSRGGCVALATGSAMGLWEVKNCTS 637
W L SF W + V++T+W+ +P + + ++ + G W+VKNC
Sbjct: 438 ETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEE 497
Query: 638 FRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSW 697
R YIC+++ G ++ G C +GW + +CYK+ + R D+ S
Sbjct: 498 -RLFYICKKA-GHVLSDAESG----------CQEGW--EETCGFCYKIDTVLRSFDQAS- 542
Query: 698 VQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQ 757
+ L+++ + E+ F+ ++++ + + +FWI L ++ G
Sbjct: 543 -----SGYYCPPALVTITNRFEQAFITSLISSVVKMKDS------YFWIALQDQNDTGEY 591
Query: 758 SWR----WSDGVGFSYHNFDRSRHDDDDI--RGCAVLDLASLQWVAMQC-DTQLDWICKI 810
+W+ + V +++ N + R+ + RG L +W C + +CK
Sbjct: 592 TWKPVGQKPEPVQYTHWNTHQPRYSGGCVAMRGRHPLG----RWEVKHCRHFKAMSLCKQ 647
Query: 811 PRGTDVREPDDSPQGRREWLRFQEAE------YKFFEHHS-----TWAQAQRICTWFQAE 859
P + + E+E +K F TW +A+ C F A
Sbjct: 648 PVENQEKAEYEERWPFHPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAH 707
Query: 860 LTSVHSQAELDFLSHNLQ-KFSRAQEQHWWIGLHTSE--SDGRFRWTDGS--IINFISWA 914
L S E +F++ L KF+ +E+ +WIG + + G + W+D + + +F+
Sbjct: 708 LASFAHIEEENFVNELLHPKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLD-- 765
Query: 915 PGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPS 974
G+D + + + C + +ICK K P +P P
Sbjct: 766 ---NTYFGEDARNCAVYKPNKTLLPLHCGSKREWICKIPRDVK----PKIPFWYQYDVPW 818
Query: 975 DWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT--- 1031
+ Q F E W +F C + L+TI + EQ FI + + ++
Sbjct: 819 LFYQDAEYLFHTFASE------WLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYG 872
Query: 1032 FDLWIGLHASQR--DFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHF 1089
WIGL + +F+W + P++Y NW G + N+ C + +
Sbjct: 873 ASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVN-----NQSQRCGFI-----SSI 922
Query: 1090 TGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGT---ELSYLNGTFRLLQKPL-- 1144
TG W C+ IC++ L P GT Y N LL P
Sbjct: 923 TGLWGSEECSVSMPS-ICKR-KKVWLIEKKKDTPKQHGTCPKGWLYFNYKCLLLNIPKDP 980
Query: 1145 ----RWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVS 1200
W A C +L + QAF+T G T +WIGL ++ +W++
Sbjct: 981 SSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGLQNDDYE---TWLN 1037
Query: 1201 EEPLNYVGWQDGEPQQPGGCTYVDVD------------------GAWRTTSCDTKLQGAV 1242
+P+ Y W + +V G W C + G V
Sbjct: 1038 GKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTGKWYFEDCGKEGYGFV 1097
Query: 1243 C---------GVSSGP--PPPRRISYHGSCPQGL-ADSAWIPFREHCYSFHMELLLGHKE 1290
C GV++ P P + Y + + A+ W + C L HK
Sbjct: 1098 CEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIKTC--------LMHK- 1148
Query: 1291 ARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVN 1350
++SI D+ F+ L W+G+ G W D T +
Sbjct: 1149 ---------AQLVSITDQYHQSFLTVVLNRL---GYAHWIGLFTTDNGLNFDWSDGTKSS 1196
Query: 1351 YSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGACTNITMGVVCKLPRAEQSSFSPSALPE 1410
++ W S+L C + SN G W AC + G +C +P + S P E
Sbjct: 1197 FTFWKDEE--SSLLG--DCVFADSN-GRWHSTACDSFLQGAICHVPPETRQSEHPELCSE 1251
Score = 133 bits (331), Expect = 2e-29
Identities = 197/936 (21%), Positives = 342/936 (36%), Gaps = 127/936 (13%)
Query: 520 GCRKGWT--WHSPSCYWLGE-DQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWE 576
GC W +S CY +++SEA C G L++IT+ E+ F+ + +
Sbjct: 230 GCDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKT 289
Query: 577 GEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRD---QPGYSRGGCVALATGSAMGLWEVK 633
E W L L+ + W G + Y +W+ + +P + C ++ W +
Sbjct: 290 VEV-WVGLNQLDEDAGWQWSDGTPLNYLNWSPEVNFEP-FVEDHCGTFSSFMPSA-WRSR 346
Query: 634 NCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQD 693
+C S YIC++ L + E+ D C GW + R CYK+ E
Sbjct: 347 DCES-TLPYICKKYLNH-IDHEIVEKDAWKYYATHCEPGW--NPYNRNCYKLQKEE---- 398
Query: 694 KKSWVQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDP 753
K+W +A +CQ + L+ + S E F+ +L E+ E WIGL+
Sbjct: 399 -KTWHEALRSCQADNSALIDITSLAEVEFLVTLLGD---ENASET------WIGLSSN-- 446
Query: 754 RGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--CAVLDLASLQWVAMQCDTQLDWICKIP 811
+ S+ WS+ + N+ R C + + W C+ +L +ICK
Sbjct: 447 KIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFYICKKA 506
Query: 812 RGTDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDF 871
+G E F YK ++ QA + L ++ ++ E F
Sbjct: 507 GHVLSDAESGCQEGWEETCGFC---YKIDTVLRSFDQASS-GYYCPPALVTITNRFEQAF 562
Query: 872 LSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTD----GSIINFISWAPGKPRPVGKDKKC 927
++ + + ++ ++WI L G + W + + W +PR G C
Sbjct: 563 ITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYSGG---C 619
Query: 928 VYMTASRE--DWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQF--LNKC 983
V M W + C + V + + C DW L C
Sbjct: 620 VAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWPFHPCYLDWESEPGLASC 679
Query: 984 FQV-QGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASL-PNVTF----DLWIG 1037
F+V ++ + W EA+ CE+ A L + + E+ F+ L P + WIG
Sbjct: 680 FKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHPKFNWTEERQFWIG 739
Query: 1038 LHA----SQRDFQWVEQEPLMYA---NWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFT 1090
+ + ++W ++ P++ + N GE + KP + LH S
Sbjct: 740 FNKRNPLNAGSWEWSDRTPVVSSFLDNTYFGEDARNCAV---YKPNKTLLPLHCGSKR-- 794
Query: 1091 GRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLLQKPLRWHDAL 1150
W IC+ D + P L Y + + W +
Sbjct: 795 -EW------------ICKIPRD--VKPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFE 839
Query: 1151 LLCESHNASLAYVPDPYTQAFLTQAARGLR---TPLWIGLAGEEGSRRYSWVSEEPLNYV 1207
+C ++ L + + Q F+ + L WIGL E + + W P+ Y
Sbjct: 840 FVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQ 899
Query: 1208 GWQDGEPQ----QPGGCTYVD-VDGAWRTTSCDTKLQGAVCG------VSSGPPPPRRIS 1256
W G + Q C ++ + G W + C + ++C + P++
Sbjct: 900 NWDTGRERTVNNQSQRCGFISSITGLWGSEECSVSMP-SICKRKKVWLIEKKKDTPKQ-- 956
Query: 1257 YHGSCPQGLADSAWIPFREHCYSFHM----ELLLGHKEARQRCQRAGGAVLSILDEMENV 1312
HG+CP+G W+ F C ++ A+ C GG +++I E+E
Sbjct: 957 -HGTCPKG-----WLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQA 1010
Query: 1313 FVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNS---- 1368
F+ +L GQ+ W+G+ + W + V YSNW P + ++ SHN+
Sbjct: 1011 FITMNLF---GQTTSVWIGLQNDDYE---TWLNGKPVVYSNWSPFDI-INIPSHNTTEVQ 1063
Query: 1369 -----CYWIQSN-----SGLWRPGACTNITMGVVCK 1394
C + SN +G W C G VC+
Sbjct: 1064 KHIPLCALLSSNPNFHFTGKWYFEDCGKEGYGFVCE 1099
Score = 70.2 bits (169), Expect = 2e-10
Identities = 63/277 (22%), Positives = 107/277 (37%), Gaps = 26/277 (9%)
Query: 1131 SYLNGTFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGE 1190
S++ F LL L W +A C+ +L + D + F+ + +W+GL
Sbjct: 241 SHICYQFNLLSS-LSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTVEVWVGLNQL 299
Query: 1191 EGSRRYSWVSEEPLNYVGWQ---DGEPQQPGGCTYVD--VDGAWRTTSCDTKLQGAVCGV 1245
+ + W PLNY+ W + EP C + AWR+ C++ L +C
Sbjct: 300 DEDAGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLP-YICKK 358
Query: 1246 SSGPPPPRRIS------YHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAG 1299
+ Y C G W P+ +CY E H EA + CQ
Sbjct: 359 YLNHIDHEIVEKDAWKYYATHCEPG-----WNPYNRNCYKLQKEEKTWH-EALRSCQADN 412
Query: 1300 GAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGL 1359
A++ I E F+ L W+G++ N + W ++++V ++NW L
Sbjct: 413 SALIDITSLAEVEFLVTLLGDENASE--TWIGLSSNKIPVSFEWSNDSSVIFTNWHT--L 468
Query: 1360 GPSMLSHNS--CYWIQSNSGLWRPGACTNITMGVVCK 1394
P + + S C + + G W+ C + +CK
Sbjct: 469 EPHIFPNRSQLCVSAEQSEGHWKVKNCEE-RLFYICK 504
>ref|NP_002340.1| lymphocyte antigen 75 [Homo sapiens]
gb|AAC17636.1| (AF011333) DEC-205 [Homo sapiens]
Length = 1722
Score = 754 bits (1926), Expect = 0.0
Identities = 455/1328 (34%), Positives = 670/1328 (50%), Gaps = 108/1328 (8%)
Query: 77 WKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLRWHCRTLGDQLSLLLGA 136
WKWVS++RLF+L + +CLG T + L M+ CD A+ L W C + L GA
Sbjct: 67 WKWVSQHRLFHLHSQKCLGLDI--TKSVNELRMFSCDSSAM-LWWKC-----EHHSLYGA 118
Query: 137 RTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQGNSHGKPCTIPFKYDNQ 196
++ S W+ GSEE LC PYHE+YT GNS+G+PC PF D
Sbjct: 119 ARYRLALKDGHGTAISNASDVWKKGGSEESLCDQPYHEIYTRDGNSYGRPCEFPFLIDGT 178
Query: 197 WFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQST 256
W H C G WCATT +Y D +WG C N CE W+K++ SCYQFN Q+
Sbjct: 179 WHHDCILDEDHSGP-WCATTLNYEYDRKWGICLKPENGCEDNWEKNEQFGSCYQFNTQTA 237
Query: 257 LSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSP 316
LSW+EA+ SC+ QGADLLSI E TY+ G + WIGLN L ++ GW+WSD+ P
Sbjct: 238 LSWKEAYVSCQNQGADLLSINSAAELTYLKE-KEGIAKIFWIGLNQLYSARGWEWSDHKP 296
Query: 317 LKYLNWESDQPDNPSEENCGVIRTES-SGGWQNRDCSIALPYVCKKKPNATAEPTPPDRW 375
L +LNW+ D+P P+ R ++ SG WQ+ C LPYVC+K N T E T D W
Sbjct: 297 LNFLNWDPDRPSAPTIGGSSCARMDAESGLWQSFSCEAQLPYVCRKPLNNTVELT--DVW 354
Query: 376 ANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQ 435
C+ W P G CY L E SW ++ C DL+SIHS+A++E + ++
Sbjct: 355 TYSDTRCDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHN 414
Query: 436 E--VEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWND 493
E EE+WIGL ++ + F+WSDG+ V+ T+W EPN + +CV+ G G+W
Sbjct: 415 EDIKEEVWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKV 474
Query: 494 SPCNQSLPSICKKAGQ-LSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDH 552
C + L +CK+ G+ L+ ++++ +GW H +CY + ED+V + L
Sbjct: 475 QSCEEKLKYVCKRKGEKLNDASSDKMCPPDEGWKRHGETCYKIYEDEVPFGTNCNL---- 530
Query: 553 GSQLVTITNRFEQAFVSSLIYNWE---GEYFWTALQDLNSTGSFFWLS----GDEVMYTH 605
TIT+RFEQ +++ L+ ++ +YFWT L+D++S G + W + V +++
Sbjct: 531 -----TITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSN 585
Query: 606 WNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSL 665
WN +P S GGCVA++TG ++G WEVK+C SF+A IC++ G P+ PE P P
Sbjct: 586 WNFLEPA-SPGGCVAMSTGKSVGKWEVKDCRSFKALSICKKMSG-PLGPEEASPKP---- 639
Query: 666 TGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEE-EHFVA 724
CP+GW S CYKVF +ER+ K++W +A+ CQ LGA L S + +E + F+
Sbjct: 640 DDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLH 699
Query: 725 NMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG 784
+ ++ G QHW WIGLN+R P SW+WSD S D DIR
Sbjct: 700 FLTDQFSG--------QHWLWIGLNKRSPDLQGSWQWSDRTPVSTIIMPNEFQQDYDIRD 751
Query: 785 CAVLDLASLQW---------------VAMQCDTQLDWICKIPRGTDVREPD----DSPQG 825
CA + + W CDT+L+W+C+IP+G + PD D
Sbjct: 752 CAAVKVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVCQIPKGRTPKTPDWYNPDRAGI 811
Query: 826 RREWLRFQEAEYKFF-EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQE 884
L + +EY F + H + +A C + L ++ S L + + + S
Sbjct: 812 HGPPLIIEGSEYWFVADLHLNYEEAVLYCASNHSFLATITSFVGLKAIKNKIANIS-GDG 870
Query: 885 QHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASR--EDWGDQR- 941
Q WWI + D F + S P PV ++C+YM+A D G
Sbjct: 871 QKWWIRISEWPIDDHFTY---------SRYPWHRFPVTFGEECLYMSAKTWLIDLGKPTD 921
Query: 942 CLTALPYICKRSNVTK-ETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEA 1000
C T LP+IC++ NV+ E PD + A C WI F NKCF +P S + +S+A
Sbjct: 922 CSTKLPFICEKYNVSSLEKYSPD--SAAKVQCSEQWIPFQNKCF--LKIKPVS-LTFSQA 976
Query: 1001 QFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLH--ASQRDFQWVEQEPLMYANW 1058
+C L ++ + +EQ FIT+ LP++ LWIGL A ++ +W + L Y+N+
Sbjct: 977 SDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATLWIGLRWTAYEKINKWTDNRELTYSNF 1036
Query: 1059 APGEPSGPSPAPSG----NKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPS 1114
P SG P CA++L+ + FTG W+ SC+E +CQK ++
Sbjct: 1037 HPLLVSGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSCSERHFVSLCQKYSEVK 1096
Query: 1115 LSPSPAALPPAPGTELSYLNGTFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQ 1174
S L A T + YLN ++++ K L WH A C N L + DPY QAFL+
Sbjct: 1097 ---SRQTLQNASET-VKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSV 1152
Query: 1175 AARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSC 1234
A + LWIGL ++ + W + L++ W + Q C +D DG W+T C
Sbjct: 1153 QALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWAETNGQLE-DCVVLDTDGFWKTVDC 1211
Query: 1235 DTKLQGAVCGVSSGPPPPRRISYHGS--CPQGLADSAWIPFREHCYSF----HMELLLGH 1288
+ GA+C SG + + S CP + ++ WIPF+ CY+F + +
Sbjct: 1212 NDNQPGAIC-YYSGNETEKEVKPVDSVKCPSPVLNTPWIPFQNCCYNFIITKNRHMATTQ 1270
Query: 1289 KEARQRCQRAG--GAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDN 1346
E +CQ+ +LSI DE EN FV E L + + LG+ + + +L+W D
Sbjct: 1271 DEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVMLGITY--RNNSLMWFDK 1328
Query: 1347 TAVNYSNW 1354
T ++Y++W
Sbjct: 1329 TPLSYTHW 1336
Score = 259 bits (654), Expect = 2e-67
Identities = 298/1283 (23%), Positives = 500/1283 (38%), Gaps = 206/1283 (16%)
Query: 274 LSITEIHEQTYINGLLTGYSSTL----WIGLNDLDTSGGWQWSD----NSPLKYLNWESD 325
L+IT EQ Y+N L+ Y +L W GL D+D+ G + W+ + + NW
Sbjct: 530 LTITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFL 589
Query: 326 QPDNPSEENCGVIRT-ESSGGWQNRDC-SIALPYVCKKKPNAT----AEPTPPDRWANVK 379
+P +P C + T +S G W+ +DC S +CKK A P P D
Sbjct: 590 EPASPG--GCVAMSTGKSVGKWEVKDCRSFKALSICKKMSGPLGPEEASPKPDD------ 641
Query: 380 VECEPSWQPFQGH--CYRL-QAE----KRSWQESKKACLRGGGDLVSIHSMAE----LEF 428
C WQ F CY++ AE KR+W+E+++ C G L S + E L F
Sbjct: 642 -PCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHF 700
Query: 429 ITKQIKQEVEELWIGLNDLK--LQMNFEWSDGSLVSFTHWHPFEPNNFRDS--LEDCVTI 484
+T Q + LWIGLN LQ +++WSD + VS PN F+ + DC +
Sbjct: 701 LTDQFSGQ-HWLWIGLNKRSPDLQGSWQWSDRTPVSTI----IMPNEFQQDYDIRDCAAV 755
Query: 485 ------WGPEGRWNDS---------PCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHS 529
W + D C+ L +C Q+ +G K W++
Sbjct: 756 KVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVC----QIPKGRTP------KTPDWYN 805
Query: 530 P--------------SCYWLGED-QVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYN 574
P S YW D + Y EA C + S L TIT+ + + I N
Sbjct: 806 PDRAGIHGPPLIIEGSEYWFVADLHLNYEEAVLYCASNHSFLATITSFVGLKAIKNKIAN 865
Query: 575 --WEGEYFWTALQDLNSTGSFFWLSGDEVMYTH--WNRDQPGYSRGGCVALATGSAMGLW 630
+G+ +W + + W D Y+ W+R + A + L
Sbjct: 866 ISGDGQKWWIRISE--------WPIDDHFTYSRYPWHRFPVTFGEECLYMSAKTWLIDLG 917
Query: 631 EVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSER 690
+ +C++ + +IC + + + E PD + C + W C+
Sbjct: 918 KPTDCST-KLPFICEKYNVSSL--EKYSPDSAAKV--QCSEQWIPFQNK--CFLKIKPVS 970
Query: 691 LQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNR 750
L ++ QA C G L S+ S E+ F+ ++L P++ WIGL
Sbjct: 971 L----TFSQASDTCHSYGGTLPSVLSQIEQDFITSLL--------PDMEAT--LWIGL-- 1014
Query: 751 RDPRGGQSWRWSDGVGFSYHNFD-----------RSRHDDDDIRGCAVLDLASLQ----- 794
R + +W+D +Y NF + +++ CA++ +LQ
Sbjct: 1015 RWTAYEKINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALI--LNLQKSPFT 1072
Query: 795 --WVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRI 852
W C ++ ++ + ++V+ + Q E +++ YK TW A+R
Sbjct: 1073 GTWNFTSC-SERHFVSLCQKYSEVKSRQ-TLQNASETVKYLNNLYKIIPKTLTWHSAKRE 1130
Query: 853 CTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFIS 912
C +L S+ + FLS + WIGL + + + F W+DG ++F
Sbjct: 1131 CLKSNMQLVSITDPYQQAFLSVQ----ALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSR 1186
Query: 913 WAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALP-YICKRSN--VTKETQPPDLPTTAL 969
WA G+ + CV + W C P IC S KE +P D
Sbjct: 1187 WAETN----GQLEDCVVLDTDGF-WKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPS 1241
Query: 970 GGCPSDWIQFLNKCFQ-VQGQEPQSRVKWSEAQFSCEQ--QEAQLVTITNPLEQAFITAS 1026
+ WI F N C+ + + E C++ ++ +++I + E F+
Sbjct: 1242 PVLNTPWIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQ 1301
Query: 1027 LPNVTFDL-WIGLHASQRD--FQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLH 1083
L + W+ L + R+ W ++ PL Y +W G P+ + T
Sbjct: 1302 LLYFNYMASWVMLGITYRNNSLMWFDKTPLSYTHWRAGRPTIKNEKFLAGLSTD------ 1355
Query: 1084 SPSAHFTGRWDDRS--CTEETHGF------ICQKGTDPSLSPSPAALPPAPGTELSYLNG 1135
G WD ++ EE F C+ LP + Y +G
Sbjct: 1356 -------GFWDIQTFKVIEEAVYFHQHSILACKIEMVDYKEEHNTTLPQF----MPYEDG 1404
Query: 1136 TFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSR- 1194
+ ++QK + W++AL +C LA V + Q FL + PLW+GL+ +GS
Sbjct: 1405 IYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDGSES 1464
Query: 1195 RYSWVSEEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRR 1254
+ W +Y+ W+ PG C +D G W+ C++ GA+C + R
Sbjct: 1465 SFEWSDGSTFDYIPWKG--QTSPGNCVLLDPKGTWKHEKCNSVKDGAICYKPTKSKKLSR 1522
Query: 1255 ISYHGSCPQGLAD-SAWIPFREHCYSFHMELLLGHKEARQRCQR--AGGAVLSILDEMEN 1311
++Y CP + S WI ++ HCY + L EA++ C + ++SI DE EN
Sbjct: 1523 LTYSSRCPAAKENGSRWIQYKGHCYKSD-QALHSFSEAKKLCSKHDHSATIVSIKDEDEN 1581
Query: 1312 VFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYW 1371
FV ++ + WLG++ + + W D + V + W S C
Sbjct: 1582 KFVSRLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKWE----NKSKSGVGRCSM 1637
Query: 1372 IQSNSGLWRPGACTNITMGVVCKLPRAEQSSFSPSALPENPAALVVVLMAVLLLLALLTA 1431
+ +++ W+ C + VVCK+P P+ A + +++A L +L L+
Sbjct: 1638 LIASNETWKKVECEHGFGRVVCKVPLG----------PDYTA--IAIIVATLSILVLMGG 1685
Query: 1432 ALILYRRRQSIERGAFEGARYSR 1454
+ +R + F RY++
Sbjct: 1686 LIWFLFQRHRLHLAGFSSVRYAQ 1708
Score = 178 bits (447), Expect = 4e-43
Identities = 236/1106 (21%), Positives = 411/1106 (36%), Gaps = 162/1106 (14%)
Query: 229 PIKSNDCETFWDKDQLTDSCYQFNFQSTL----SWREAWASCEQQGADLLSITEIHE-QT 283
P + C W + SCY+ + +W EA C+ GA L S + + E +
Sbjct: 637 PKPDDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKE 696
Query: 284 YINGLLTGYSST--LWIGLNDL--DTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIR 339
+++ L +S LWIGLN D G WQWSD +P+ + ++ + +C ++
Sbjct: 697 FLHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPVSTIIMPNEFQQDYDIRDCAAVK 756
Query: 340 TESSG---GWQNRD-----------CSIALPYVCKKKPNATAEPTPPDRWANVKVECEPS 385
GW D C L +VC+ T P PD + +
Sbjct: 757 VFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVCQIPKGRT--PKTPDWYNPDRAGIHGP 814
Query: 386 WQPFQGHCYRLQAEKR-SWQESKKACLRGGGDLVSIHSMAELEFITKQIKQ---EVEELW 441
+G Y A+ +++E+ C L +I S L+ I +I + ++ W
Sbjct: 815 PLIIEGSEYWFVADLHLNYEEAVLYCASNHSFLATITSFVGLKAIKNKIANISGDGQKWW 874
Query: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPE-GRWNDSPCNQSL 500
I +++ + +F +S WH F + L W + G+ D C+ L
Sbjct: 875 IRISEWPIDDHFTYSRYP------WHRFPVTFGEECLYMSAKTWLIDLGKPTD--CSTKL 926
Query: 501 PSICKKAGQLSQGAAEEDHG----CRKGWTWHSPSCYW-LGEDQVTYSEARRLCTDHGSQ 555
P IC+K S D C + W C+ + +T+S+A C +G
Sbjct: 927 PFICEKYNVSSLEKYSPDSAAKVQCSEQWIPFQNKCFLKIKPVSLTFSQASDTCHSYGGT 986
Query: 556 LVTITNRFEQAFVSSLIYNWEGEYF----WTALQDLNSTGSFFWLSGDEVMYTHWN---- 607
L ++ ++ EQ F++SL+ + E + WTA + +N W E+ Y++++
Sbjct: 987 LPSVLSQIEQDFITSLLPDMEATLWIGLRWTAYEKINK-----WTDNRELTYSNFHPLLV 1041
Query: 608 -----------RDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPEL 656
++ Y + L G W +C+ +C++ L
Sbjct: 1042 SGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSCSERHFVSLCQKYSEVKSRQTL 1101
Query: 657 PGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLAS 716
T L YK+ + +W A+ C + QL+S+
Sbjct: 1102 QNASETVKY-------------LNNLYKI-----IPKTLTWHSAKRECLKSNMQLVSITD 1143
Query: 717 YEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSR 776
++ F++ + +H WIGL +D ++ WSDG +F R
Sbjct: 1144 PYQQAFLS---------VQALLHNSS-LWIGLFSQDDE--LNFGWSDGKRL---HFSRWA 1188
Query: 777 HDDDDIRGCAVLDLASLQWVAMQC-DTQLDWICKIPRGTDVRE--PDDS-----PQGRRE 828
+ + C VLD W + C D Q IC +E P DS P
Sbjct: 1189 ETNGQLEDCVVLDTDGF-WKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTP 1247
Query: 829 WLRFQEAEYKFF---EHH--STWAQAQRICTWF--QAELTSVHSQAELDFLSHNLQKFSR 881
W+ FQ Y F H +T + C ++ + S+ + E +F+ L F+
Sbjct: 1248 WIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNY 1307
Query: 882 AQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQ- 940
W+ L + + W D + +++ W G RP K++K + ++ W Q
Sbjct: 1308 MAS---WVMLGITYRNNSLMWFDKTPLSYTHWRAG--RPTIKNEKFLAGLSTDGFWDIQT 1362
Query: 941 -RCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSE 999
+ + Y + S + + + D P ++ + + + V Q +V W E
Sbjct: 1363 FKVIEEAVYFHQHSILACKIEMVDYKEEHNTTLPQ-FMPYEDGIYSVI----QKKVTWYE 1417
Query: 1000 AQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLHA---SQRDFQWVEQEPLMYA 1056
A C Q L ++ N Q F+ + F LW+GL + S+ F+W + Y
Sbjct: 1418 ALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYI 1477
Query: 1057 NWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPS-- 1114
W G+ S P +C VL P G W C G IC K T
Sbjct: 1478 PW-KGQTS----------PGNC--VLLDPK----GTWKHEKCNSVKDGAICYKPTKSKKL 1520
Query: 1115 -----LSPSPAALPPAPGTELSYLNGTFRLLQKPLRWHDALLLC--ESHNASLAYVPDPY 1167
S PAA + Y ++ Q + +A LC H+A++ + D
Sbjct: 1521 SRLTYSSRCPAAKENG-SRWIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDED 1579
Query: 1168 TQAFLTQAAR---GLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQPGGCT-YV 1223
F+++ R + +W+GL+ + +SW+ + +V W++ G C+ +
Sbjct: 1580 ENKFVSRLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKWENKSKSGVGRCSMLI 1639
Query: 1224 DVDGAWRTTSCDTKLQGAVCGVSSGP 1249
+ W+ C+ VC V GP
Sbjct: 1640 ASNETWKKVECEHGFGRVVCKVPLGP 1665
Score = 125 bits (312), Expect = 3e-27
Identities = 107/429 (24%), Positives = 182/429 (41%), Gaps = 38/429 (8%)
Query: 248 CYQF----NFQSTLSWREAWASCEQQG--ADLLSITEIHEQTYINGLLTGYS-STLWIGL 300
CY F N + E C++ + +LSI + E ++ L ++ W+ L
Sbjct: 1255 CYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVML 1314
Query: 301 NDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCK 360
+ W D +PL Y +W + +P +E+ + T+ G W + + V
Sbjct: 1315 GITYRNNSLMWFDKTPLSYTHWRAGRPTIKNEKFLAGLSTD--GFWDIQTFKVIEEAVYF 1372
Query: 361 KKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSI 420
+ + A + P + P++ Y + +K +W E+ C + GG L S+
Sbjct: 1373 HQHSILACKIEMVDYKEEHNTTLPQFMPYEDGIYSVIQKKVTWYEALNMCSQSGGHLASV 1432
Query: 421 HSMAELEFITKQIKQEVEELWIGLNDLK-LQMNFEWSDGSLVSFTHWHPFEPNNFRDSLE 479
H+ F+ +K++ LW+GL+ + +FEWSDGS + W + S
Sbjct: 1433 HNQNGQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYIPW------KGQTSPG 1486
Query: 480 DCVTIWGPEGRWNDSPCNQ-------SLPSICKKAGQL---SQGAAEEDHGCRKGWTWHS 529
+CV + P+G W CN P+ KK +L S+ A +++G R W +
Sbjct: 1487 NCVLL-DPKGTWKHEKCNSVKDGAICYKPTKSKKLSRLTYSSRCPAAKENGSR--WIQYK 1543
Query: 530 PSCYWLGEDQVTYSEARRLCT--DHGSQLVTITNRFEQAFVSSLI--YNWEGEYFWTALQ 585
CY + ++SEA++LC+ DH + +V+I + E FVS L+ N W L
Sbjct: 1544 GHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRVWLGLS 1603
Query: 586 DLNSTGSFFWLSGDEVMYTHW-NRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYIC 644
+ S+ WL G EV + W N+ + G R C L + W+ C R +C
Sbjct: 1604 QHSVDQSWSWLDGSEVTFVKWENKSKSGVGR--CSMLIASNE--TWKKVECEHGFGRVVC 1659
Query: 645 RQSLGTPVT 653
+ LG T
Sbjct: 1660 KVPLGPDYT 1668
Score = 63.6 bits (152), Expect = 2e-08
Identities = 36/120 (30%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 1277 CYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFNP 1336
CY F+ + L KEA CQ G +LSI E + L+ EG ++ W+G+N
Sbjct: 229 CYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTY----LKEKEGIAKIFWIGLNQLY 284
Query: 1337 KGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGACTNITMGVVCKLP 1396
W D+ +N+ NW P + +SC + + SGLW+ +C + VC+ P
Sbjct: 285 SARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMDAESGLWQSFSC-EAQLPYVCRKP 343
>gb|AAC62622.1| (AF064827) gp200-MR6 [Homo sapiens]
Length = 1722
Score = 754 bits (1925), Expect = 0.0
Identities = 456/1328 (34%), Positives = 670/1328 (50%), Gaps = 108/1328 (8%)
Query: 77 WKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLRWHCRTLGDQLSLLLGA 136
WKWVS++RLF+L + +CLG T + L M+ CD A+ L W C + L GA
Sbjct: 67 WKWVSQHRLFHLHSQKCLGLDI--TKSVNELRMFSCDSSAM-LWWKC-----EHHSLYGA 118
Query: 137 RTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQGNSHGKPCTIPFKYDNQ 196
++ S W+ GSEE LC PYHE+YT GNS+G+PC PF D
Sbjct: 119 ARYRLALKDGHGTAISNASDVWKKGGSEESLCDQPYHEIYTRDGNSYGRPCEFPFLIDGT 178
Query: 197 WFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQST 256
W H C G WCATT +Y D +WG C N CE W+K++ SCYQFN Q+
Sbjct: 179 WHHDCILDEDHSGP-WCATTLNYEYDRKWGICLKPENGCEDNWEKNEQFGSCYQFNTQTA 237
Query: 257 LSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSP 316
LSW+EA+ SC+ QGADLLSI E TY+ G + WIGLN L ++ GW+WSD+ P
Sbjct: 238 LSWKEAYVSCQNQGADLLSINSAAELTYLKD-KEGIAKIFWIGLNQLYSARGWEWSDHKP 296
Query: 317 LKYLNWESDQPDNPSEENCGVIRTES-SGGWQNRDCSIALPYVCKKKPNATAEPTPPDRW 375
L +LNW+ D+P P+ R ++ SG WQ+ C LPYVC+K N T E T D W
Sbjct: 297 LNFLNWDPDRPSAPTIGGSSCARMDAESGLWQSFSCEAQLPYVCRKPLNNTVELT--DVW 354
Query: 376 ANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQ 435
C+ W P G CY L E SW ++ C DL+SIHS+A++E + ++
Sbjct: 355 TYSDTRCDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHN 414
Query: 436 E--VEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWND 493
E EE+WIGL ++ + F+WSDG+ V+ T+W EPN + +CV+ G G+W
Sbjct: 415 EDIKEEVWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKV 474
Query: 494 SPCNQSLPSICKKAGQ-LSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDH 552
C + L +CK+ G+ L+ ++++ +GW H +CY + ED+V + L
Sbjct: 475 QSCEEKLKYVCKRKGEKLNDASSDKMCPPDEGWKRHGETCYKIYEDEVPFGTNCNL---- 530
Query: 553 GSQLVTITNRFEQAFVSSLIYNWE---GEYFWTALQDLNSTGSFFWLS----GDEVMYTH 605
TIT+RFEQ +++ L+ ++ +YFWT L+D++S G + W + V +++
Sbjct: 531 -----TITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSN 585
Query: 606 WNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSL 665
WN +P S GGCVA++TG ++G WEVK+C SF+A IC++ G P+ PE P P
Sbjct: 586 WNFLEPA-SPGGCVAMSTGKSVGKWEVKDCRSFKALSICKKMSG-PLGPEEASPKP---- 639
Query: 666 TGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEE-EHFVA 724
CP+GW S CYKVF +ER+ K++W +A+ CQ LGA L S + +E + F+
Sbjct: 640 DDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLH 699
Query: 725 NMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG 784
+ ++ G QHW WIGLN+R P SW+WSD S D DIR
Sbjct: 700 FLTDQFSG--------QHWLWIGLNKRSPDLQGSWQWSDRTPVSTIIMPNEFQQDYDIRD 751
Query: 785 CAVLDLASLQW---------------VAMQCDTQLDWICKIPRGTDVREPDDSPQGRR-- 827
CA + + W CDT+L+W+C+IP+G + PD R
Sbjct: 752 CAAVKVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVCQIPKGRTPKTPDWYNPERAGI 811
Query: 828 --EWLRFQEAEYKFF-EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQE 884
L + +EY F + H + +A C + L ++ S L + + + S
Sbjct: 812 HGPPLIIEGSEYWFVADLHLNYEEAVLYCASNHSFLATITSFVGLKAIKNKIANIS-GDG 870
Query: 885 QHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASR--EDWGDQR- 941
Q WWI + D F + S P PV ++C+YM+A D G
Sbjct: 871 QKWWIRISEWPIDDHFTY---------SRYPWHRFPVTFGEECLYMSAKTWLIDLGKPTD 921
Query: 942 CLTALPYICKRSNVTK-ETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEA 1000
C T LP+IC++ NV+ E PD + A C WI F NKCF +P S + +S+A
Sbjct: 922 CSTKLPFICEKYNVSSLEKYSPD--SAAKVQCSEQWIPFQNKCF--LKIKPVS-LTFSQA 976
Query: 1001 QFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLH--ASQRDFQWVEQEPLMYANW 1058
+C L ++ + +EQ FIT+ LP++ LWIGL A ++ +W + L Y+N+
Sbjct: 977 SDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATLWIGLRWTAYEKINKWTDNRELTYSNF 1036
Query: 1059 APGEPSGPSPAPSG----NKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPS 1114
P SG P CA++L+ + FTG W+ SC+E +CQK ++
Sbjct: 1037 HPLLVSGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSCSERHFVSLCQKYSEVK 1096
Query: 1115 LSPSPAALPPAPGTELSYLNGTFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQ 1174
S L A T + YLN ++++ K L WH A C N L + DPY QAFL+
Sbjct: 1097 ---SRQTLQNASET-VKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSV 1152
Query: 1175 AARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSC 1234
A + LWIGL ++ + W + L++ W + Q C +D DG W+T C
Sbjct: 1153 QALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWAETNGQLE-DCVVLDTDGFWKTVDC 1211
Query: 1235 DTKLQGAVCGVSSGPPPPRRISYHGS--CPQGLADSAWIPFREHCYSF----HMELLLGH 1288
+ GA+C SG + + S CP + ++ WIPF+ CY+F + +
Sbjct: 1212 NDNQPGAIC-YYSGNETEKEVKPVDSVKCPSPVLNTPWIPFQNCCYNFIITKNRHMATTQ 1270
Query: 1289 KEARQRCQRAG--GAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDN 1346
E +CQ+ +LSI DE EN FV E L + + LG+ + K +L+W D
Sbjct: 1271 DEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVMLGITYRNK--SLMWFDK 1328
Query: 1347 TAVNYSNW 1354
T ++Y++W
Sbjct: 1329 TPLSYTHW 1336
Score = 259 bits (654), Expect = 2e-67
Identities = 297/1283 (23%), Positives = 499/1283 (38%), Gaps = 206/1283 (16%)
Query: 274 LSITEIHEQTYINGLLTGYSSTL----WIGLNDLDTSGGWQWSD----NSPLKYLNWESD 325
L+IT EQ Y+N L+ Y +L W GL D+D+ G + W+ + + NW
Sbjct: 530 LTITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFL 589
Query: 326 QPDNPSEENCGVIRT-ESSGGWQNRDC-SIALPYVCKKKPNAT----AEPTPPDRWANVK 379
+P +P C + T +S G W+ +DC S +CKK A P P D
Sbjct: 590 EPASPG--GCVAMSTGKSVGKWEVKDCRSFKALSICKKMSGPLGPEEASPKPDD------ 641
Query: 380 VECEPSWQPFQGH--CYRL-QAE----KRSWQESKKACLRGGGDLVSIHSMAE----LEF 428
C WQ F CY++ AE KR+W+E+++ C G L S + E L F
Sbjct: 642 -PCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHF 700
Query: 429 ITKQIKQEVEELWIGLNDLK--LQMNFEWSDGSLVSFTHWHPFEPNNFRDS--LEDCVTI 484
+T Q + LWIGLN LQ +++WSD + VS PN F+ + DC +
Sbjct: 701 LTDQFSGQ-HWLWIGLNKRSPDLQGSWQWSDRTPVSTI----IMPNEFQQDYDIRDCAAV 755
Query: 485 ------WGPEGRWNDS---------PCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHS 529
W + D C+ L +C Q+ +G K W++
Sbjct: 756 KVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVC----QIPKGRTP------KTPDWYN 805
Query: 530 P--------------SCYWLGED-QVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYN 574
P S YW D + Y EA C + S L TIT+ + + I N
Sbjct: 806 PERAGIHGPPLIIEGSEYWFVADLHLNYEEAVLYCASNHSFLATITSFVGLKAIKNKIAN 865
Query: 575 --WEGEYFWTALQDLNSTGSFFWLSGDEVMYTH--WNRDQPGYSRGGCVALATGSAMGLW 630
+G+ +W + + W D Y+ W+R + A + L
Sbjct: 866 ISGDGQKWWIRISE--------WPIDDHFTYSRYPWHRFPVTFGEECLYMSAKTWLIDLG 917
Query: 631 EVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSER 690
+ +C++ + +IC + + + E PD + C + W C+
Sbjct: 918 KPTDCST-KLPFICEKYNVSSL--EKYSPDSAAKV--QCSEQWIPFQNK--CFLKIKPVS 970
Query: 691 LQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNR 750
L ++ QA C G L S+ S E+ F+ ++L P++ WIGL
Sbjct: 971 L----TFSQASDTCHSYGGTLPSVLSQIEQDFITSLL--------PDMEAT--LWIGL-- 1014
Query: 751 RDPRGGQSWRWSDGVGFSYHNFD-----------RSRHDDDDIRGCAVLDLASLQ----- 794
R + +W+D +Y NF + +++ CA++ +LQ
Sbjct: 1015 RWTAYEKINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALI--LNLQKSPFT 1072
Query: 795 --WVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRI 852
W C ++ ++ + ++V+ + Q E +++ YK TW A+R
Sbjct: 1073 GTWNFTSC-SERHFVSLCQKYSEVKSRQ-TLQNASETVKYLNNLYKIIPKTLTWHSAKRE 1130
Query: 853 CTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFIS 912
C +L S+ + FLS + WIGL + + + F W+DG ++F
Sbjct: 1131 CLKSNMQLVSITDPYQQAFLSVQ----ALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSR 1186
Query: 913 WAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALP-YICKRSN--VTKETQPPDLPTTAL 969
WA G+ + CV + W C P IC S KE +P D
Sbjct: 1187 WAETN----GQLEDCVVLDTDGF-WKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPS 1241
Query: 970 GGCPSDWIQFLNKCFQ-VQGQEPQSRVKWSEAQFSCEQ--QEAQLVTITNPLEQAFITAS 1026
+ WI F N C+ + + E C++ ++ +++I + E F+
Sbjct: 1242 PVLNTPWIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQ 1301
Query: 1027 LPNVTFDL-WI--GLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLH 1083
L + W+ G+ + W ++ PL Y +W G P+ + T
Sbjct: 1302 LLYFNYMASWVMLGITYRNKSLMWFDKTPLSYTHWRAGRPTIKNEKFLAGLSTD------ 1355
Query: 1084 SPSAHFTGRWDDRS--CTEETHGF------ICQKGTDPSLSPSPAALPPAPGTELSYLNG 1135
G WD ++ EE F C+ LP + Y +G
Sbjct: 1356 -------GFWDIQTFKVIEEAVYFHQHSILACKIEMVDYKEEYNTTLPQF----MPYEDG 1404
Query: 1136 TFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSR- 1194
+ ++QK + W++AL +C LA V + Q FL + PLW+GL+ +GS
Sbjct: 1405 IYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDGSES 1464
Query: 1195 RYSWVSEEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRR 1254
+ W +Y+ W+ PG C +D G W+ C++ GA+C + R
Sbjct: 1465 SFEWSDGSTFDYIPWKG--QTSPGNCVLLDPKGTWKHEKCNSVKDGAICYKPTKSKKLSR 1522
Query: 1255 ISYHGSCPQGLAD-SAWIPFREHCYSFHMELLLGHKEARQRCQR--AGGAVLSILDEMEN 1311
++Y CP + S WI ++ HCY + L EA++ C + ++SI DE EN
Sbjct: 1523 LTYSSRCPAAKENGSRWIQYKGHCYKSD-QALHSFSEAKKLCSKHDHSATIVSIKDEDEN 1581
Query: 1312 VFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYW 1371
FV ++ + WLG++ + + W D + V + W S C
Sbjct: 1582 KFVSRLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKWE----NKSKSGVGRCSM 1637
Query: 1372 IQSNSGLWRPGACTNITMGVVCKLPRAEQSSFSPSALPENPAALVVVLMAVLLLLALLTA 1431
+ +++ W+ C + VVCK+P P+ A + +++A L +L L+
Sbjct: 1638 LIASNETWKKVECEHGFGRVVCKVPLG----------PDYTA--IAIIVATLSILVLMGG 1685
Query: 1432 ALILYRRRQSIERGAFEGARYSR 1454
+ +R + F RY++
Sbjct: 1686 LIWFLFQRHRLHLAGFSSVRYAQ 1708
Score = 178 bits (446), Expect = 5e-43
Identities = 236/1106 (21%), Positives = 411/1106 (36%), Gaps = 162/1106 (14%)
Query: 229 PIKSNDCETFWDKDQLTDSCYQFNFQSTL----SWREAWASCEQQGADLLSITEIHE-QT 283
P + C W + SCY+ + +W EA C+ GA L S + + E +
Sbjct: 637 PKPDDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKE 696
Query: 284 YINGLLTGYSST--LWIGLNDL--DTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIR 339
+++ L +S LWIGLN D G WQWSD +P+ + ++ + +C ++
Sbjct: 697 FLHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPVSTIIMPNEFQQDYDIRDCAAVK 756
Query: 340 TESSG---GWQNRD-----------CSIALPYVCKKKPNATAEPTPPDRWANVKVECEPS 385
GW D C L +VC+ T P PD + +
Sbjct: 757 VFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVCQIPKGRT--PKTPDWYNPERAGIHGP 814
Query: 386 WQPFQGHCYRLQAEKR-SWQESKKACLRGGGDLVSIHSMAELEFITKQIKQ---EVEELW 441
+G Y A+ +++E+ C L +I S L+ I +I + ++ W
Sbjct: 815 PLIIEGSEYWFVADLHLNYEEAVLYCASNHSFLATITSFVGLKAIKNKIANISGDGQKWW 874
Query: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPE-GRWNDSPCNQSL 500
I +++ + +F +S WH F + L W + G+ D C+ L
Sbjct: 875 IRISEWPIDDHFTYSRYP------WHRFPVTFGEECLYMSAKTWLIDLGKPTD--CSTKL 926
Query: 501 PSICKKAGQLSQGAAEEDHG----CRKGWTWHSPSCYW-LGEDQVTYSEARRLCTDHGSQ 555
P IC+K S D C + W C+ + +T+S+A C +G
Sbjct: 927 PFICEKYNVSSLEKYSPDSAAKVQCSEQWIPFQNKCFLKIKPVSLTFSQASDTCHSYGGT 986
Query: 556 LVTITNRFEQAFVSSLIYNWEGEYF----WTALQDLNSTGSFFWLSGDEVMYTHWN---- 607
L ++ ++ EQ F++SL+ + E + WTA + +N W E+ Y++++
Sbjct: 987 LPSVLSQIEQDFITSLLPDMEATLWIGLRWTAYEKINK-----WTDNRELTYSNFHPLLV 1041
Query: 608 -----------RDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPEL 656
++ Y + L G W +C+ +C++ L
Sbjct: 1042 SGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSCSERHFVSLCQKYSEVKSRQTL 1101
Query: 657 PGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLAS 716
T L YK+ + +W A+ C + QL+S+
Sbjct: 1102 QNASETVKY-------------LNNLYKI-----IPKTLTWHSAKRECLKSNMQLVSITD 1143
Query: 717 YEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSR 776
++ F++ + +H WIGL +D ++ WSDG +F R
Sbjct: 1144 PYQQAFLS---------VQALLHNSS-LWIGLFSQDDE--LNFGWSDGKRL---HFSRWA 1188
Query: 777 HDDDDIRGCAVLDLASLQWVAMQC-DTQLDWICKIPRGTDVRE--PDDS-----PQGRRE 828
+ + C VLD W + C D Q IC +E P DS P
Sbjct: 1189 ETNGQLEDCVVLDTDGF-WKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTP 1247
Query: 829 WLRFQEAEYKFF---EHH--STWAQAQRICTWF--QAELTSVHSQAELDFLSHNLQKFSR 881
W+ FQ Y F H +T + C ++ + S+ + E +F+ L F+
Sbjct: 1248 WIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNY 1307
Query: 882 AQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQ- 940
W+ L + + W D + +++ W G RP K++K + ++ W Q
Sbjct: 1308 MAS---WVMLGITYRNKSLMWFDKTPLSYTHWRAG--RPTIKNEKFLAGLSTDGFWDIQT 1362
Query: 941 -RCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSE 999
+ + Y + S + + + D P ++ + + + V Q +V W E
Sbjct: 1363 FKVIEEAVYFHQHSILACKIEMVDYKEEYNTTLPQ-FMPYEDGIYSVI----QKKVTWYE 1417
Query: 1000 AQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLHA---SQRDFQWVEQEPLMYA 1056
A C Q L ++ N Q F+ + F LW+GL + S+ F+W + Y
Sbjct: 1418 ALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYI 1477
Query: 1057 NWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPS-- 1114
W G+ S P +C VL P G W C G IC K T
Sbjct: 1478 PW-KGQTS----------PGNC--VLLDPK----GTWKHEKCNSVKDGAICYKPTKSKKL 1520
Query: 1115 -----LSPSPAALPPAPGTELSYLNGTFRLLQKPLRWHDALLLC--ESHNASLAYVPDPY 1167
S PAA + Y ++ Q + +A LC H+A++ + D
Sbjct: 1521 SRLTYSSRCPAAKENG-SRWIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDED 1579
Query: 1168 TQAFLTQAAR---GLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQPGGCT-YV 1223
F+++ R + +W+GL+ + +SW+ + +V W++ G C+ +
Sbjct: 1580 ENKFVSRLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKWENKSKSGVGRCSMLI 1639
Query: 1224 DVDGAWRTTSCDTKLQGAVCGVSSGP 1249
+ W+ C+ VC V GP
Sbjct: 1640 ASNETWKKVECEHGFGRVVCKVPLGP 1665
Score = 124 bits (309), Expect = 6e-27
Identities = 107/429 (24%), Positives = 182/429 (41%), Gaps = 38/429 (8%)
Query: 248 CYQF----NFQSTLSWREAWASCEQQG--ADLLSITEIHEQTYINGLLTGYS-STLWIGL 300
CY F N + E C++ + +LSI + E ++ L ++ W+ L
Sbjct: 1255 CYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVML 1314
Query: 301 NDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCK 360
+ W D +PL Y +W + +P +E+ + T+ G W + + V
Sbjct: 1315 GITYRNKSLMWFDKTPLSYTHWRAGRPTIKNEKFLAGLSTD--GFWDIQTFKVIEEAVYF 1372
Query: 361 KKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSI 420
+ + A + P + P++ Y + +K +W E+ C + GG L S+
Sbjct: 1373 HQHSILACKIEMVDYKEEYNTTLPQFMPYEDGIYSVIQKKVTWYEALNMCSQSGGHLASV 1432
Query: 421 HSMAELEFITKQIKQEVEELWIGLNDLK-LQMNFEWSDGSLVSFTHWHPFEPNNFRDSLE 479
H+ F+ +K++ LW+GL+ + +FEWSDGS + W + S
Sbjct: 1433 HNQNGQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYIPW------KGQTSPG 1486
Query: 480 DCVTIWGPEGRWNDSPCNQ-------SLPSICKKAGQL---SQGAAEEDHGCRKGWTWHS 529
+CV + P+G W CN P+ KK +L S+ A +++G R W +
Sbjct: 1487 NCVLL-DPKGTWKHEKCNSVKDGAICYKPTKSKKLSRLTYSSRCPAAKENGSR--WIQYK 1543
Query: 530 PSCYWLGEDQVTYSEARRLCT--DHGSQLVTITNRFEQAFVSSLI--YNWEGEYFWTALQ 585
CY + ++SEA++LC+ DH + +V+I + E FVS L+ N W L
Sbjct: 1544 GHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRVWLGLS 1603
Query: 586 DLNSTGSFFWLSGDEVMYTHW-NRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYIC 644
+ S+ WL G EV + W N+ + G R C L + W+ C R +C
Sbjct: 1604 QHSVDQSWSWLDGSEVTFVKWENKSKSGVGR--CSMLIASNE--TWKKVECEHGFGRVVC 1659
Query: 645 RQSLGTPVT 653
+ LG T
Sbjct: 1660 KVPLGPDYT 1668
Score = 63.6 bits (152), Expect = 2e-08
Identities = 36/120 (30%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 1277 CYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFNP 1336
CY F+ + L KEA CQ G +LSI E + L+ EG ++ W+G+N
Sbjct: 229 CYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTY----LKDKEGIAKIFWIGLNQLY 284
Query: 1337 KGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGACTNITMGVVCKLP 1396
W D+ +N+ NW P + +SC + + SGLW+ +C + VC+ P
Sbjct: 285 SARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMDAESGLWQSFSC-EAQLPYVCRKP 343
>ref|NP_038853.1| lymphocyte antigen 75 [Mus musculus]
pir||S58880 receptor DEC-205 - mouse
gb|AAA80215.1| (U19271) DEC205 [Mus musculus]
Length = 1723
Score = 723 bits (1845), Expect = 0.0
Identities = 449/1332 (33%), Positives = 649/1332 (48%), Gaps = 115/1332 (8%)
Query: 77 WKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLRWHCRTLGDQLSLLLGA 136
WKWVS++RLF+L + +CLG T T +L M+ CD + L W C + SL A
Sbjct: 67 WKWVSQHRLFHLESQKCLGLDI--TKATDNLRMFSCDSTVM-LWWKC----EHHSLYTAA 119
Query: 137 RTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQGNSHGKPCTIPFKYDNQ 196
+ K G T S W+ GSEE+LCA PYHE+YT GNS+G+PC PF
Sbjct: 120 QYRLALKDGYAVANTNT-SDVWKKGGSEENLCAQPYHEIYTRDGNSYGRPCEFPFLIGET 178
Query: 197 WFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQST 256
W+H C G WCATT Y D++WG C + + CE W+K++ SCYQFN Q
Sbjct: 179 WYHDCIHDEDHSGP-WCATTLSYEYDQKWGICLLPESGCEGNWEKNEQIGSCYQFNNQEI 237
Query: 257 LSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSP 316
LSW+EA+ SC+ QGADLLSI E YI G + +W+GLN L ++ GW+WSD P
Sbjct: 238 LSWKEAYVSCQNQGADLLSIHSAAELAYITG-KEDIARLVWLGLNQLYSARGWEWSDFRP 296
Query: 317 LKYLNWESDQPDNP--SEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDR 374
LK+LNW+ P P +C + TE SG WQ+ C PYVCKK N T E PD
Sbjct: 297 LKFLNWDPGTPVAPVIGGSSCARMDTE-SGLWQSVSCESQQPYVCKKPLNNTLE--LPDV 353
Query: 375 WANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELE-FITKQI 433
W C W P G CY L E SW + C G DL+S+HS+A++E +TK
Sbjct: 354 WTYTDTHCHVGWLPNNGFCYLLANESSSWDAAHLKCKAFGADLISMHSLADVEVVVTKLH 413
Query: 434 KQEV-EELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWN 492
+V +E+W GL + F+WSDG+ V+ T+W+ EP+ + +CV+ G G+W
Sbjct: 414 NGDVKKEIWTGLKNTNSPALFQWSDGTEVTLTYWNENEPSVPFNKTPNCVSYLGKLGQWK 473
Query: 493 DSPCNQSLPSICKKAGQLSQGAAEEDHGC--RKGWTWHSPSCYWLGEDQVTYSEARRLCT 550
C + L +CKK G++++ AE D C +GW H +CY + E + + L
Sbjct: 474 VQSCEKKLRYVCKKKGEITKD-AESDKLCPPDEGWKRHGETCYKIYEKEAPFGTNCNL-- 530
Query: 551 DHGSQLVTITNRFEQAFVSSLIYNWE---GEYFWTALQDLNSTGSFFWLSG----DEVMY 603
TIT+RFEQ F++ ++ N++ +YFWT L+D +S G + W V +
Sbjct: 531 -------TITSRFEQEFLNYMMKNYDKSLRKYFWTGLRDPDSRGEYSWAVAQGVKQAVTF 583
Query: 604 THWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTP 663
++WN +P S GGCVA++TG +G WEVKNC SFRA IC++ + P PE P P
Sbjct: 584 SNWNFLEPA-SPGGCVAMSTGKTLGKWEVKNCRSFRALSICKK-VSEPQEPEEAAPKP-- 639
Query: 664 SLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFV 723
CP+GW + CYKVF ER+ K++W +A+ CQ LGA L S + EE
Sbjct: 640 --DDPCPEGWHTFPSSLSCYKVFHIERIVRKRNWEEAERFCQALGAHLPSFSRREEIKDF 697
Query: 724 ANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIR 783
++L F Q W WIGLN+R P SW+WSD S + D DIR
Sbjct: 698 VHLLKDQFS-------GQRWLWIGLNKRSPDLQGSWQWSDRTPVSAVMMEPEFQQDFDIR 750
Query: 784 GCAVLDLASL---------------QWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRR- 827
CA + + + W CD +L+W+C+IP+G+ + PD R
Sbjct: 751 DCAAIKVLDVPWRRVWHLYEDKDYAYWKPFACDAKLEWVCQIPKGSTPQMPDWYNPERTG 810
Query: 828 ---EWLRFQEAEYKFF-EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQ 883
+ + +EY F + H + +A C + L ++ S L + + L S +
Sbjct: 811 IHGPPVIIEGSEYWFVADPHLNYEEAVLYCASNHSFLATITSFTGLKAIKNKLANIS-GE 869
Query: 884 EQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDW-----G 938
EQ WW+ + D F + + + P+ +C++M+A + W
Sbjct: 870 EQKWWVKTSENPIDRYFLGSRRRLWHHF--------PMTFGDECLHMSA--KTWLVDLSK 919
Query: 939 DQRCLTALPYICKRSNVTK-ETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKW 997
C LP+IC+R NV+ E PD A C WI F NKCF P V +
Sbjct: 920 RADCNAKLPFICERYNVSSLEKYSPD--PAAKVQCTEKWIPFQNKCFLKVNSGP---VTF 974
Query: 998 SEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLH--ASQRDFQWVEQEPLMY 1055
S+A C L ++ + EQ FI + LP + LWIGL A +R +W + L Y
Sbjct: 975 SQASGICHSYGGTLPSVLSRGEQDFIISLLPEMEASLWIGLRWTAYERINRWTDNRELTY 1034
Query: 1056 ANWAP----GEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGT 1111
+N+ P S P+ CA++L+ + TG W+ SC+E +CQK +
Sbjct: 1035 SNFHPLLVGRRLSIPTNFFDDESHFHCALILNLKKSPLTGTWNFTSCSERHSLSLCQKYS 1094
Query: 1112 DPSLSPSPAALPPAPGTE--LSYLNGTFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQ 1169
+ P T + YLN ++++ KPL WH AL C L + DPY Q
Sbjct: 1095 ETEDG------QPWENTSKTVKYLNNLYKIISKPLTWHGALKECMKEKMRLVSITDPYQQ 1148
Query: 1170 AFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQPGGCTYVDVDGAW 1229
AFL A + WIGL+ ++ + W + L + W G +Q C +D DG W
Sbjct: 1149 AFLAVQATLRNSSFWIGLSSQDDELNFGWSDGKRLQFSNWA-GSNEQLDDCVILDTDGFW 1207
Query: 1230 RTTSCDTKLQGAVCGVSSGPPPPR-RISYHGSCPQGLADSAWIPFREHCYSF----HMEL 1284
+T CD GA+C R CP + + WIPF+ CY+F +
Sbjct: 1208 KTADCDDNQPGAICYYPGNETEEEVRALDTAKCPSPVQSTPWIPFQNSCYNFMITNNRHK 1267
Query: 1285 LLGHKEARQRCQRAGGAV--LSILDEMENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLV 1342
+ +E + C++ LSI +E EN FV E L + + LG+ + + +L+
Sbjct: 1268 TVTPEEVQSTCEKLHPKAHSLSIRNEEENTFVVEQLLYFNYIASWVMLGITY--ENNSLM 1325
Query: 1343 WQDNTAVNYSNW 1354
W D TA++Y++W
Sbjct: 1326 WFDKTALSYTHW 1337
Score = 256 bits (646), Expect = 2e-66
Identities = 302/1276 (23%), Positives = 489/1276 (37%), Gaps = 185/1276 (14%)
Query: 274 LSITEIHEQTYINGLLTGYSSTL----WIGLNDLDTSGGWQWSDNSPLK----YLNWESD 325
L+IT EQ ++N ++ Y +L W GL D D+ G + W+ +K + NW
Sbjct: 530 LTITSRFEQEFLNYMMKNYDKSLRKYFWTGLRDPDSRGEYSWAVAQGVKQAVTFSNWNFL 589
Query: 326 QPDNPSEENCGVIRT-ESSGGWQNRDC-SIALPYVCKKKPNATAEPTPPDRWANVKVE-C 382
+P +P C + T ++ G W+ ++C S +CKK +EP P+ A + C
Sbjct: 590 EPASPG--GCVAMSTGKTLGKWEVKNCRSFRALSICKK----VSEPQEPEEAAPKPDDPC 643
Query: 383 EPSWQPFQGH--CYRLQ-----AEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQ 435
W F CY++ KR+W+E+++ C G L S E++ +K
Sbjct: 644 PEGWHTFPSSLSCYKVFHIERIVRKRNWEEAERFCQALGAHLPSFSRREEIKDFVHLLKD 703
Query: 436 EVEE---LWIGLNDLK--LQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTI------ 484
+ LWIGLN LQ +++WSD + VS P +F + DC I
Sbjct: 704 QFSGQRWLWIGLNKRSPDLQGSWQWSDRTPVSAVMMEPEFQQDF--DIRDCAAIKVLDVP 761
Query: 485 ----WG-----PEGRWNDSPCNQSLPSICK----KAGQLSQGAAEEDHGCRKGWTWHSPS 531
W W C+ L +C+ Q+ E G S
Sbjct: 762 WRRVWHLYEDKDYAYWKPFACDAKLEWVCQIPKGSTPQMPDWYNPERTGIHGPPVIIEGS 821
Query: 532 CYWLGED-QVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGE-YFWTALQDLNS 589
YW D + Y EA C + S L TIT+ + + + N GE W N
Sbjct: 822 EYWFVADPHLNYEEAVLYCASNHSFLATITSFTGLKAIKNKLANISGEEQKWWVKTSENP 881
Query: 590 TGSFFWLSGDEVMYTHWNRDQPGYSRGGCVALATGS-AMGLWEVKNCTSFRARYICRQSL 648
+F L ++ H+ P C+ ++ + + L + +C + + +IC +
Sbjct: 882 IDRYF-LGSRRRLWHHF----PMTFGDECLHMSAKTWLVDLSKRADCNA-KLPFICERYN 935
Query: 649 GTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELG 708
+ + E PDP + C + W C+ +S + ++ QA G C G
Sbjct: 936 VSSL--EKYSPDPAAKV--QCTEKWIPFQNK--CFLKVNSGPV----TFSQASGICHSYG 985
Query: 709 AQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWF---WIGLNRRDPRGGQSWRWSDGV 765
L S+ S E+ F+ ++L PE+ W W R + RW+D
Sbjct: 986 GTLPSVLSRGEQDFIISLL--------PEMEASLWIGLRWTAYERIN-------RWTDNR 1030
Query: 766 GFSYHNFD-----------RSRHDDDDIRGCA-VLDLASLQ----WVAMQCDTQLDW-IC 808
+Y NF + DD+ CA +L+L W C + +C
Sbjct: 1031 ELTYSNFHPLLVGRRLSIPTNFFDDESHFHCALILNLKKSPLTGTWNFTSCSERHSLSLC 1090
Query: 809 KIPRGTDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAE 868
+ T+ +P ++ + +++ YK TW A + C + L S+ +
Sbjct: 1091 QKYSETEDGQPWENTS---KTVKYLNNLYKIISKPLTWHGALKECMKEKMRLVSITDPYQ 1147
Query: 869 LDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPVGKDKKCV 928
FL+ + + +WIGL + + + F W+DG + F +WA + CV
Sbjct: 1148 QAFLAVQ----ATLRNSSFWIGLSSQDDELNFGWSDGKRLQFSNWAGSNEQL----DDCV 1199
Query: 929 YMTASREDWGDQRCLTALP-YICKRSNVTKETQPPDLPTTALGGCPSD-----WIQFLNK 982
+ W C P IC E + L T CPS WI F N
Sbjct: 1200 ILDTDGF-WKTADCDDNQPGAICYYPGNETEEEVRALDTAK---CPSPVQSTPWIPFQNS 1255
Query: 983 CFQVQGQEPQSR-VKWSEAQFSCEQ--QEAQLVTITNPLEQAFITASLPNVTFDL-WI-- 1036
C+ + + V E Q +CE+ +A ++I N E F+ L + W+
Sbjct: 1256 CYNFMITNNRHKTVTPEEVQSTCEKLHPKAHSLSIRNEEENTFVVEQLLYFNYIASWVML 1315
Query: 1037 GLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDR 1096
G+ W ++ L Y +W G P+ + T G WD +
Sbjct: 1316 GITYENNSLMWFDKTALSYTHWRTGRPTVKNGKFLAGLSTD-------------GFWDIQ 1362
Query: 1097 SCT--EETHGFI------CQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLLQKPLRWHD 1148
S EET F C+ LP + Y +G + ++QK + W++
Sbjct: 1363 SFNVIEETLHFYQHSISACKIEMVDYEDKHNGTLPQF----IPYKDGVYSVIQKKVTWYE 1418
Query: 1149 ALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSR-RYSWVSEEPLNYV 1207
AL C LA V +P + FL PLW+GL+ +GS + W +YV
Sbjct: 1419 ALNACSQSGGELASVHNPNGKLFLEDIVNRDGFPLWVGLSSHDGSESSFEWSDGRAFDYV 1478
Query: 1208 GWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYH---GSCPQG 1264
WQ Q PG C + G WR C + GA+C P +++ +H CP
Sbjct: 1479 PWQ--SLQSPGDCVVLYPKGIWRREKCLSVKDGAIC---YKPTKDKKLIFHVKSSKCPVA 1533
Query: 1265 LADS-AWIPFREHCYSFHMELLLGHKEARQRCQRA--GGAVLSILDEMENVFVWEHLQSY 1321
D W+ + HCY+ ++L EA+Q CQ V++I DE EN FV ++
Sbjct: 1534 KRDGPQWVQYGGHCYASD-QVLHSFSEAKQVCQELDHSATVVTIADENENKFVSRLMREN 1592
Query: 1322 EGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWRP 1381
+ WLG++ + + W D V + W + C + +++ WR
Sbjct: 1593 YNITMRVWLGLSQHSLDQSWSWLDGLDVTFVKWE----NKTKDGDGKCSILIASNETWRK 1648
Query: 1382 GACTNITMGVVCKLPRAEQSSFSPSALPENPAALVVVLMAVLLLLALLTAALILYRRRQS 1441
C+ VCK+P SP + +L AVL LL L++ A+ +R
Sbjct: 1649 VHCSRGYARAVCKIP------LSPDYTG------IAILFAVLCLLGLISLAIWFLLQRSH 1696
Query: 1442 IERGAFEGARYSRSSS 1457
I F RY ++
Sbjct: 1697 IRWTGFSSVRYEHGTN 1712
Score = 189 bits (474), Expect = 3e-46
Identities = 248/1110 (22%), Positives = 415/1110 (37%), Gaps = 169/1110 (15%)
Query: 229 PIKSNDCETFWDKDQLTDSCYQ-FNFQSTL---SWREAWASCEQQGADLLSITEIHE-QT 283
P + C W + SCY+ F+ + + +W EA C+ GA L S + E +
Sbjct: 637 PKPDDPCPEGWHTFPSSLSCYKVFHIERIVRKRNWEEAERFCQALGAHLPSFSRREEIKD 696
Query: 284 YINGLLTGYSST--LWIGLNDL--DTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIR 339
+++ L +S LWIGLN D G WQWSD +P+ + E + + +C I+
Sbjct: 697 FVHLLKDQFSGQRWLWIGLNKRSPDLQGSWQWSDRTPVSAVMMEPEFQQDFDIRDCAAIK 756
Query: 340 T--------------ESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPS 385
+ W+ C L +VC+ +T P PD + +
Sbjct: 757 VLDVPWRRVWHLYEDKDYAYWKPFACDAKLEWVCQIPKGST--PQMPDWYNPERTGIHGP 814
Query: 386 WQPFQGHCYRLQAEKR-SWQESKKACLRGGGDLVSIHSMAELEFITKQ---IKQEVEELW 441
+G Y A+ +++E+ C L +I S L+ I + I E ++ W
Sbjct: 815 PVIIEGSEYWFVADPHLNYEEAVLYCASNHSFLATITSFTGLKAIKNKLANISGEEQKWW 874
Query: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDS-LEDCVTIWGPEGRWNDSPCNQSL 500
+ ++ + F S L WH F P F D L W + + CN L
Sbjct: 875 VKTSENPIDRYFLGSRRRL-----WHHF-PMTFGDECLHMSAKTWLVDLS-KRADCNAKL 927
Query: 501 PSICKKAGQLSQGAAEEDHG----CRKGWTWHSPSCYW-LGEDQVTYSEARRLCTDHGSQ 555
P IC++ S D C + W C+ + VT+S+A +C +G
Sbjct: 928 PFICERYNVSSLEKYSPDPAAKVQCTEKWIPFQNKCFLKVNSGPVTFSQASGICHSYGGT 987
Query: 556 LVTITNRFEQAFVSSLIYNWEGEYF----WTALQDLNSTGSFFWLSGDEVMYTHWNR--- 608
L ++ +R EQ F+ SL+ E + WTA + +N W E+ Y++++
Sbjct: 988 LPSVLSRGEQDFIISLLPEMEASLWIGLRWTAYERINR-----WTDNRELTYSNFHPLLV 1042
Query: 609 ------------DQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPEL 656
D+ + + L G W +C+ + +C++ T
Sbjct: 1043 GRRLSIPTNFFDDESHFHCALILNLKKSPLTGTWNFTSCSERHSLSLCQKYSETE----- 1097
Query: 657 PGPDPTPSLTGSCPQGWASDTK----LRYCYKVFSSERLQDKKSWVQAQGACQELGAQLL 712
D P W + +K L YK+ S +W A C + +L+
Sbjct: 1098 ---DGQP---------WENTSKTVKYLNNLYKIISKPL-----TWHGALKECMKEKMRLV 1140
Query: 713 SLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNF 772
S+ ++ F+A FWIGL+ +D ++ WSDG + N+
Sbjct: 1141 SITDPYQQAFLAVQATL----------RNSSFWIGLSSQDDE--LNFGWSDGKRLQFSNW 1188
Query: 773 DRSRHDDDDIRGCAVLDLASLQWVAMQCD-TQLDWICKIPRGT---DVREPDD----SPQ 824
S DD C +LD W CD Q IC P +VR D SP
Sbjct: 1189 AGSNEQLDD---CVILDTDGF-WKTADCDDNQPGAICYYPGNETEEEVRALDTAKCPSPV 1244
Query: 825 GRREWLRFQEAEYKFF---EHHSTWA--QAQRICTWF--QAELTSVHSQAELDFLSHNLQ 877
W+ FQ + Y F H T + Q C +A S+ ++ E F+ L
Sbjct: 1245 QSTPWIPFQNSCYNFMITNNRHKTVTPEEVQSTCEKLHPKAHSLSIRNEEENTFVVEQLL 1304
Query: 878 KFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDW 937
F+ W+ L + + W D + +++ W G RP K+ K + ++ W
Sbjct: 1305 YFNYIAS---WVMLGITYENNSLMWFDKTALSYTHWRTG--RPTVKNGKFLAGLSTDGFW 1359
Query: 938 GDQ--RCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRV 995
Q + + + S + + D G P +I + + + V Q +V
Sbjct: 1360 DIQSFNVIEETLHFYQHSISACKIEMVDYEDKHNGTLPQ-FIPYKDGVYSVI----QKKV 1414
Query: 996 KWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLHA---SQRDFQWVEQEP 1052
W EA +C Q +L ++ NP + F+ + F LW+GL + S+ F+W +
Sbjct: 1415 TWYEALNACSQSGGELASVHNPNGKLFLEDIVNRDGFPLWVGLSSHDGSESSFEWSDGRA 1474
Query: 1053 LMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGT- 1111
Y W S P C V+ + G W C G IC K T
Sbjct: 1475 FDYVPW-----------QSLQSPGDCVVL------YPKGIWRREKCLSVKDGAICYKPTK 1517
Query: 1112 DPSL------SPSPAALPPAPGTELSYLNGTFRLLQKPLRWHDALLLCE--SHNASLAYV 1163
D L S P A P + Y + Q + +A +C+ H+A++ +
Sbjct: 1518 DKKLIFHVKSSKCPVAKRDGP-QWVQYGGHCYASDQVLHSFSEAKQVCQELDHSATVVTI 1576
Query: 1164 PDPYTQAFLTQAAR---GLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQPGGC 1220
D F+++ R + +W+GL+ + +SW+ + +V W++ G C
Sbjct: 1577 ADENENKFVSRLMRENYNITMRVWLGLSQHSLDQSWSWLDGLDVTFVKWENKTKDGDGKC 1636
Query: 1221 T-YVDVDGAWRTTSCDTKLQGAVCGVSSGP 1249
+ + + WR C AVC + P
Sbjct: 1637 SILIASNETWRKVHCSRGYARAVCKIPLSP 1666
Score = 114 bits (283), Expect = 7e-24
Identities = 109/437 (24%), Positives = 192/437 (42%), Gaps = 44/437 (10%)
Query: 246 DSCYQF----NFQSTLSWREAWASCEQ--QGADLLSITEIHEQTYINGLLTGYSSTL-WI 298
+SCY F N T++ E ++CE+ A LSI E T++ L ++ W+
Sbjct: 1254 NSCYNFMITNNRHKTVTPEEVQSTCEKLHPKAHSLSIRNEEENTFVVEQLLYFNYIASWV 1313
Query: 299 GLNDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYV 358
L + W D + L Y +W + +P + + + T+ G W + ++ +
Sbjct: 1314 MLGITYENNSLMWFDKTALSYTHWRTGRPTVKNGKFLAGLSTD--GFWDIQSFNVIEETL 1371
Query: 359 CKKKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLV 418
+ + +A + + P + P++ Y + +K +W E+ AC + GG+L
Sbjct: 1372 HFYQHSISACKIEMVDYEDKHNGTLPQFIPYKDGVYSVIQKKVTWYEALNACSQSGGELA 1431
Query: 419 SIHSMAELEFITKQIKQEVEELWIGLNDLK-LQMNFEWSDGSLVSFTHWHPFEPNNFRDS 477
S+H+ F+ + ++ LW+GL+ + +FEWSDG + W + S
Sbjct: 1432 SVHNPNGKLFLEDIVNRDGFPLWVGLSSHDGSESSFEWSDGRAFDYVPWQSLQ------S 1485
Query: 478 LEDCVTIWGPEGRWNDSPC-NQSLPSICKKAGQ-----LSQGAAEEDHGCRKG--WTWHS 529
DCV ++ P+G W C + +IC K + +++ R G W +
Sbjct: 1486 PGDCVVLY-PKGIWRREKCLSVKDGAICYKPTKDKKLIFHVKSSKCPVAKRDGPQWVQYG 1544
Query: 530 PSCYWLGEDQV--TYSEARRLC--TDHGSQLVTITNRFEQAFVSSLI---YNWEGEYFWT 582
CY DQV ++SEA+++C DH + +VTI + E FVS L+ YN W
Sbjct: 1545 GHCY--ASDQVLHSFSEAKQVCQELDHSATVVTIADENENKFVSRLMRENYNITMR-VWL 1601
Query: 583 ALQDLNSTGSFFWLSGDEVMYTHW-NRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRAR 641
L + S+ WL G +V + W N+ + G G C L + W +C+ AR
Sbjct: 1602 GLSQHSLDQSWSWLDGLDVTFVKWENKTKDG--DGKCSILIASNE--TWRKVHCSRGYAR 1657
Query: 642 YICRQSLGTPVTPELPG 658
+C+ P++P+ G
Sbjct: 1658 AVCK----IPLSPDYTG 1670
Score = 58.9 bits (140), Expect = 4e-07
Identities = 45/159 (28%), Positives = 67/159 (41%), Gaps = 14/159 (8%)
Query: 1247 SGPPPPRRISYH-----GSC--PQGLADSAWIPFRE--HCYSFHMELLLGHKEARQRCQR 1297
SGP +SY G C P+ + W + CY F+ + +L KEA CQ
Sbjct: 190 SGPWCATTLSYEYDQKWGICLLPESGCEGNWEKNEQIGSCYQFNNQEILSWKEAYVSCQN 249
Query: 1298 AGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPP 1357
G +LSI E ++ E +R WLG+N W D + + NW P
Sbjct: 250 QGADLLSIHSAAELAYI----TGKEDIARLVWLGLNQLYSARGWEWSDFRPLKFLNWDPG 305
Query: 1358 GLGPSMLSHNSCYWIQSNSGLWRPGACTNITMGVVCKLP 1396
++ +SC + + SGLW+ +C + VCK P
Sbjct: 306 TPVAPVIGGSSCARMDTESGLWQSVSCES-QQPYVCKKP 343
>ref|XP_005830.1| mannose receptor, C type 1 [Homo sapiens]
Length = 1189
Score = 681 bits (1737), Expect = 0.0
Identities = 394/1221 (32%), Positives = 618/1221 (50%), Gaps = 67/1221 (5%)
Query: 287 GLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGW 346
GL + +S LWIGLN L + GWQWSD SP +YLNW P ++C + + W
Sbjct: 1 GLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKW 60
Query: 347 QNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQA-EKRSWQE 405
+N +C L Y+CKK N T ++V C W P+ GHCY++ EK+ ++
Sbjct: 61 ENLECVQKLGYICKKG-NTTLNSFVIPSESDVPTHCPSQWWPYAGHCYKIHRDEKKIQRD 119
Query: 406 SKKACLRGGGDLVSIHSMAELEFITKQIKQEV-EELWIGLNDLKLQMNFEWSDGSLVSFT 464
+ C + G DL SIH++ E +FI Q+ E +ELWIGLND+K+QM FEWSDG+ V+FT
Sbjct: 120 ALTTCRKEGSDLASIHTIEEFDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFT 179
Query: 465 HWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGA--AEEDHGCR 522
W EP++ + EDCV + G +G W D C L ICK + SQG E + GCR
Sbjct: 180 KWLRGEPSHENNRQEDCVVMKGKDGYWADRGCEWPLGYICKMKSR-SQGPEIVEVEKGCR 238
Query: 523 KGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWT 582
KGW H CY +G T++EA + C + + L TI +R+EQAF++S + +YFWT
Sbjct: 239 KGWKKHHFYCYMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVGLRPEKYFWT 298
Query: 583 ALQDLNSTGSFFWLSGDEVMYTHWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARY 642
L D+ + G+F W +EV +THWN D PG + GCVA+ TG A GLW+V C +A++
Sbjct: 299 GLSDIQTKGTFQWTIEEEVRFTHWNSDMPG-RKPGCVAMRTGIAGGLWDVLKCDE-KAKF 356
Query: 643 ICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQG 702
+C+ P P P P CP+ W + ++ C+K+++ + +KK+W +++
Sbjct: 357 VCKHWAEGVTHPPKPTTTPEP----KCPEDWGASSRTSLCFKLYAKGK-HEKKTWFESRD 411
Query: 703 ACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWS 762
C+ LG L S+ + EE+ + ++ + H+ FW+GL P G + WS
Sbjct: 412 FCRALGGDLASINNKEEQQTIWRLIT-----ASGSYHK--LFWLGLTYGSPSEG--FTWS 462
Query: 763 DGVGFSYHNFDRSRHDD-DDIRGCAVL-DLASLQWVAMQCDTQLDWICKIPRG-TDVREP 819
DG SY N+ ++ ++ C L ++ W + C+ +WIC+I +G T EP
Sbjct: 463 DGSPVSYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQKGQTPKPEP 522
Query: 820 DDSPQGRRE-----WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSH 874
+PQ W+ +++ +Y F + T A+ C +L S+ S++E FL
Sbjct: 523 TPAPQDNPPVTEDGWVIYKDYQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWK 582
Query: 875 NLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASR 934
+ + + ++IGL S D +F W DGS ++++SWA G+P +D+ CV M ++
Sbjct: 583 YVNR--NDAQSAYFIGLLIS-LDKKFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNS 639
Query: 935 EDWGDQRCLTALPYICKR--SNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQ 992
W D C +IC+R S++ T P +P+ GC W + NKCF++ G +
Sbjct: 640 GFWNDINCGYPNAFICQRHNSSINATTVMPTMPSVP-SGCKEGWNFYSNKCFKIFGFMEE 698
Query: 993 SRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLH--ASQRDFQWVEQ 1050
R W EA+ +C LV+I N EQAF+T + + TF W GL+ S+ F W +
Sbjct: 699 ERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTDG 758
Query: 1051 EPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKG 1110
+ Y NW G P G + S + C V++ S + G+W D +C + G+ICQ
Sbjct: 759 RGVHYTNWGKGYPGGRRSSLS-YEDADCVVIIGGAS-NEAGKWMDDTC-DSKRGYICQTR 815
Query: 1111 TDPSLSPSPAALPPAPGTELSYLNGTFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQA 1170
+DPSL+ PA + + Y ++ L+++ +WH+A C+ HN+ +A + DPY+ A
Sbjct: 816 SDPSLTNPPATI--QTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSNA 873
Query: 1171 FLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQPGGCTYVDVDGAWR 1230
F +WI L +Y+W + + Y W EP+ C Y+D+DG W+
Sbjct: 874 FAWLQMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLDGYWK 933
Query: 1231 TTSCDTKLQGAVCGVSSGPPPPRRISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKE 1290
T C+ +C S P G CP+ +AWIPF HCY +
Sbjct: 934 TAHCNESFY-FLCKRSDEIPATEPPQLPGRCPES-DHTAWIPFHGHCYYIESSYTRNWGQ 991
Query: 1291 ARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVN 1350
A C R G +++SI E+ F+ ++ + ++ W+G+ F GT +W +N+ V+
Sbjct: 992 ASLECLRMGSSLVSIESAAESSFLSYRVEPLKSKT-NFWIGL-FRNVEGTWLWINNSPVS 1049
Query: 1351 YSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGACTNITMGVVCKLP-------------- 1396
+ NW G N C + ++SG W C++ G +CK P
Sbjct: 1050 FVNW---NTGDPSGERNDCVALHASSGFWSNIHCSSY-KGYICKRPKIIDAKPTHELLTT 1105
Query: 1397 RAEQSSFSPSALPENPAALVVVLMAVLLLLALLTAALILYRRRQSI-ERGAFEGARYSRS 1455
+A+ PS N A +V++++ ++L A L A +RR + + GAFE Y S
Sbjct: 1106 KADTRKMDPSKPSSNVAGVVIIVILLILTGAGLAAYFFYKKRRVHLPQEGAFENTLYFNS 1165
Query: 1456 SSSPTEATEKNILVSDMEMNE 1476
SSP + K+ LV ++E NE
Sbjct: 1166 QSSPGTSDMKD-LVGNIEQNE 1185
Score = 280 bits (710), Expect = 6e-74
Identities = 256/1052 (24%), Positives = 432/1052 (40%), Gaps = 125/1052 (11%)
Query: 248 CYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGY--SSTLWIGLNDLDT 305
CY+ + R+A +C ++G+DL SI I E +I L GY + LWIGLND+
Sbjct: 106 CYKIHRDEKKIQRDALTTCRKEGSDLASIHTIEEFDFIISQL-GYEPNDELWIGLNDIKI 164
Query: 306 SGGWQWSDNSPLKYLNWESDQP--DNPSEENCGVIRTESSGGWQNRDCSIALPYVCKKKP 363
++WSD +P+ + W +P +N +E+C V+ G W +R C L Y+CK K
Sbjct: 165 QMYFEWSDGTPVTFTKWLRGEPSHENNRQEDC-VVMKGKDGYWADRGCEWPLGYICKMKS 223
Query: 364 NATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSM 423
+ V+ C W+ +CY + ++ E+ + C L +I
Sbjct: 224 RSQGPEI-----VEVEKGCRKGWKKHHFYCYMIGHTLSTFAEANQTCNNENAYLTTIEDR 278
Query: 424 AELEFITKQIKQEVEE-LWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCV 482
E F+T + E+ W GL+D++ + F+W+ V FTHW+ P +
Sbjct: 279 YEQAFLTSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTHWNSDMPGRKPGCVAMRT 338
Query: 483 TIWGPEGRWNDSPCNQSLPSICKKAGQ----LSQGAAEEDHGCRKGWTWHSPS--CYWL- 535
I G G W+ C++ +CK + + + C + W S + C+ L
Sbjct: 339 GIAG--GLWDVLKCDEKAKFVCKHWAEGVTHPPKPTTTPEPKCPEDWGASSRTSLCFKLY 396
Query: 536 ---GEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEY---FWTALQDLNS 589
++ T+ E+R C G L +I N+ EQ + LI G Y FW L +
Sbjct: 397 AKGKHEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLI-TASGSYHKLFWLGLTYGSP 455
Query: 590 TGSFFWLSGDEVMYTHWNRDQP-GYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSL 648
+ F W G V Y +W +P Y G W NC +IC+
Sbjct: 456 SEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLN-NWICQIQK 514
Query: 649 GTPVTPELPGPDPTPSLTGSCP---QGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQ 705
G + P P+PTP+ + P GW YK + ++K++ A+ C+
Sbjct: 515 G-----QTPKPEPTPAPQDNPPVTEDGWV-------IYKDYQYYFSKEKETMDNARAFCK 562
Query: 706 ELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGV 765
L+S+ S E+ F+ +N+ +S ++IGL + + W DG
Sbjct: 563 RNFGDLVSIQSESEKKFLWKYVNRNDAQSA--------YFIGLLISLDK---KFAWMDGS 611
Query: 766 GFSYHNFDRSRHD-DDDIRGCAVLDLASLQWVAMQCDTQLDWICK-----IPRGTDVREP 819
Y ++ + ++ C + S W + C +IC+ I T +
Sbjct: 612 KVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINCGYPNAFICQRHNSSINATTVMPTM 671
Query: 820 DDSPQGRRE-WLRFQEAEYKFF----EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSH 874
P G +E W + +K F E W +A++ C F L S+ ++ E FL++
Sbjct: 672 PSVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTY 731
Query: 875 NLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPVGK-------DKKC 927
+++ + + W GL+ S+ F WTDG +++ +W GK P G+ D C
Sbjct: 732 HMKDSTFSA----WTGLNDVNSEHTFLWTDGRGVHYTNW--GKGYPGGRRSSLSYEDADC 785
Query: 928 VYMT--ASRE--DWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKC 983
V + AS E W D C + YIC+ + T PP T ++++
Sbjct: 786 VVIIGGASNEAGKWMDDTCDSKRGYICQTRSDPSLTNPPATIQT------DGFVKYGKSS 839
Query: 984 FQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLHASQR 1043
+ + Q + +W EA+ C+ + + +I +P AF + +WI L+++
Sbjct: 840 YSLMRQ----KFQWHEAETYCKLHNSLIASILDPYSNAFAWLQMETSNERVWIALNSNLT 895
Query: 1044 D--FQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEE 1101
D + W ++ + Y NWA EP K S V L G W C E
Sbjct: 896 DNQYTWTDKWRVRYTNWAADEP----------KLKSACVYL-----DLDGYWKTAHCNES 940
Query: 1102 THGFICQKGTD-PSLSPS--PAALPPAPGTELSYLNGTFRLLQKPL--RWHDALLLCESH 1156
+ F+C++ + P+ P P P + T +G ++ W A L C
Sbjct: 941 FY-FLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRNWGQASLECLRM 999
Query: 1157 NASLAYVPDPYTQAFLTQAARGL--RTPLWIGL-AGEEGSRRYSWVSEEPLNYVGWQDGE 1213
+SL + +FL+ L +T WIGL EG+ + W++ P+++V W G+
Sbjct: 1000 GSSLVSIESAAESSFLSYRVEPLKSKTNFWIGLFRNVEGT--WLWINNSPVSFVNWNTGD 1057
Query: 1214 PQ-QPGGCTYVDV-DGAWRTTSCDTKLQGAVC 1243
P + C + G W C + +G +C
Sbjct: 1058 PSGERNDCVALHASSGFWSNIHC-SSYKGYIC 1088
Score = 146 bits (365), Expect = 2e-33
Identities = 107/440 (24%), Positives = 190/440 (42%), Gaps = 43/440 (9%)
Query: 229 PIKSNDCETFWDKDQLTDSCYQ---FNFQSTLSWREAWASCEQQGADLLSITEIHEQTYI 285
P + C+ W+ ++ C++ F + +W+EA +C G +L+SI EQ ++
Sbjct: 672 PSVPSGCKEGWNF--YSNKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFL 729
Query: 286 NGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPD------NPSEENCGVI- 338
+ + + W GLND+++ + W+D + Y NW P + + +C VI
Sbjct: 730 TYHMKDSTFSAWTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVII 789
Query: 339 --RTESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRL 396
+ +G W + C Y+C+ + ++P+ + A ++ + + + Y L
Sbjct: 790 GGASNEAGKWMDDTCDSKRGYICQTR----SDPSLTNPPATIQTD---GFVKYGKSSYSL 842
Query: 397 QAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWS 456
+K W E++ C + SI F Q++ E +WI LN + W+
Sbjct: 843 MRQKFQWHEAETYCKLHNSLIASILDPYSNAFAWLQMETSNERVWIALNSNLTDNQYTWT 902
Query: 457 DGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSICKKAG-------- 508
D V +T+W EP L+ +G W + CN+S +CK++
Sbjct: 903 DKWRVRYTNWAADEP-----KLKSACVYLDLDGYWKTAHCNESFYFLCKRSDEIPATEPP 957
Query: 509 QLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQV-TYSEARRLCTDHGSQLVTITNRFEQAF 567
QL E DH W CY++ + +A C GS LV+I + E +F
Sbjct: 958 QLPGRCPESDH---TAWIPFHGHCYYIESSYTRNWGQASLECLRMGSSLVSIESAAESSF 1014
Query: 568 VSSLIYNWEGE-YFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQPGYSRGGCVALATGSA 626
+S + + + FW L N G++ W++ V + +WN P R CVAL S
Sbjct: 1015 LSYRVEPLKSKTNFWIGL-FRNVEGTWLWINNSPVSFVNWNTGDPSGERNDCVALHASS- 1072
Query: 627 MGLWEVKNCTSFRARYICRQ 646
G W +C+S++ YIC++
Sbjct: 1073 -GFWSNIHCSSYKG-YICKR 1090
>dbj|BAA06445.1| (D30781) phospholipase A2 receptor [Rattus sp.]
Length = 409
Score = 282 bits (715), Expect = 2e-74
Identities = 154/410 (37%), Positives = 227/410 (54%), Gaps = 28/410 (6%)
Query: 556 LVTITNRFEQAFVSSLIYNW--EGEYFWTALQDLNSTGSFFWLS---GDEVMYTHWNRDQ 610
L+TIT+RFEQAF++SLI + + YFW ALQD N+TG + W + + V YTHWN Q
Sbjct: 18 LLTITSRFEQAFITSLISSVARKDSYFWIALQDQNNTGEYTWKTMGQREPVQYTHWNAHQ 77
Query: 611 PGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCP 670
P Y GGCV L GS+ G WEVKNC+ F+A +C+ + E G P C
Sbjct: 78 PSY-HGGCVVLRGGSSFGRWEVKNCSDFKAMSLCKTPIKVWEKTEFEGRWPFHP----CY 132
Query: 671 QGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLNKI 730
W S+T L C+KVF SE++ K+SW +A+ C+E GA L S A EEE+FV +L+
Sbjct: 133 MDWESETGLASCFKVFHSEKVLMKRSWREAEAFCEEFGAHLASFAHIEEENFVNKLLHSK 192
Query: 731 FGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRGCAVLDL 790
F + ++ FWIG N+R+P SW WSDG +F + + ++D + CAV
Sbjct: 193 FNWT-----QERQFWIGFNKRNPLNAGSWEWSDGSPV-VSSFLDNAYFEEDAKNCAVYK- 245
Query: 791 ASLQWVAMQCDTQLDWICKIPRGTDVREP----DDSPQGRREWLRFQEAEYKFFEHHSTW 846
A+ + C ++ +WICKIPR P D+P WL +Q AEY F H + W
Sbjct: 246 ANNTLLPSNCASKHEWICKIPRDVKPNFPVWYQYDAP-----WLFYQNAEYLFHTHPAEW 300
Query: 847 AQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGS 906
A + +C W +++ +++S E +F+ ++ S+ +WWIGL + + W++GS
Sbjct: 301 ATFEFVCGWLRSDFLTIYSAQEQEFIHSKIRALSK-YGANWWIGLEDRRAGDQIHWSNGS 359
Query: 907 IINFISWAPG-KPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNV 955
+ F +W G K R + K+CV+M+A WG + C +P ICKR +
Sbjct: 360 PVIFQNWDKGRKGRMDSQRKRCVFMSAITGLWGTENCSVPMPSICKRVKI 409
Score = 110 bits (273), Expect = 1e-22
Identities = 86/301 (28%), Positives = 128/301 (41%), Gaps = 37/301 (12%)
Query: 224 RWGFCPIKSNDCETFWDKDQLTDSCYQ-FNFQSTL---SWREAWASCEQQGADLLSITEI 279
RW F P C W+ + SC++ F+ + L SWREA A CE+ GA L S I
Sbjct: 125 RWPFHP-----CYMDWESETGLASCFKVFHSEKVLMKRSWREAEAFCEEFGAHLASFAHI 179
Query: 280 HEQTYINGLLTG-----YSSTLWIGLNDLD--TSGGWQWSDNSPL--KYLNWESDQPDNP 330
E+ ++N LL WIG N + +G W+WSD SP+ +L+ + D
Sbjct: 180 EEENFVNKLLHSKFNWTQERQFWIGFNKRNPLNAGSWEWSDGSPVVSSFLDNAYFEED-- 237
Query: 331 SEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKV--ECEPSWQP 388
+NC V + ++ N C+ ++CK P D N V + + W
Sbjct: 238 -AKNCAVYKANNTLLPSN--CASKHEWICK---------IPRDVKPNFPVWYQYDAPWLF 285
Query: 389 FQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVE---ELWIGLN 445
+Q Y W + C D ++I+S E EFI +I+ + WIGL
Sbjct: 286 YQNAEYLFHTHPAEWATFEFVCGWLRSDFLTIYSAQEQEFIHSKIRALSKYGANWWIGLE 345
Query: 446 DLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSICK 505
D + WS+GS V F +W + CV + G W C+ +PSICK
Sbjct: 346 DRRAGDQIHWSNGSPVIFQNWDKGRKGRMDSQRKRCVFMSAITGLWGTENCSVPMPSICK 405
Query: 506 K 506
+
Sbjct: 406 R 406
Score = 100 bits (247), Expect = 1e-19
Identities = 98/399 (24%), Positives = 165/399 (40%), Gaps = 54/399 (13%)
Query: 273 LLSITEIHEQTYINGLLTGYS---STLWIGLNDLDTSGGWQW---SDNSPLKYLNWESDQ 326
LL+IT EQ +I L++ + S WI L D + +G + W P++Y +W + Q
Sbjct: 18 LLTITSRFEQAFITSLISSVARKDSYFWIALQDQNNTGEYTWKTMGQREPVQYTHWNAHQ 77
Query: 327 PDNPSEENCGVIRTESS-GGWQNRDCS-IALPYVCKKKPNATAEPTPPDRWANVKVE--- 381
P C V+R SS G W+ ++CS +CK TP W + E
Sbjct: 78 PS--YHGGCVVLRGGSSFGRWEVKNCSDFKAMSLCK---------TPIKVWEKTEFEGRW 126
Query: 382 ----CEPSWQPFQG--HCYRL-----QAEKRSWQESKKACLRGGGDLVSIHSMAELEFIT 430
C W+ G C+++ KRSW+E++ C G L S + E F+
Sbjct: 127 PFHPCYMDWESETGLASCFKVFHSEKVLMKRSWREAEAFCEEFGAHLASFAHIEEENFVN 186
Query: 431 KQIKQ-----EVEELWIGLNDLKLQMN---FEWSDGSLVSFTHWHPFEPNNFRDSLEDCV 482
K + + + WIG N + +N +EWSDGS V + + F + ++C
Sbjct: 187 KLLHSKFNWTQERQFWIGFNK-RNPLNAGSWEWSDGSPVVSSF---LDNAYFEEDAKNC- 241
Query: 483 TIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTY 542
++ S C ICK + + W ++ + Y +
Sbjct: 242 AVYKANNTLLPSNCASKHEWICKIPRDVKPNFPVW-YQYDAPWLFYQNAEYLFHTHPAEW 300
Query: 543 SEARRLCTDHGSQLVTITNRFEQAFVSSLI--YNWEGEYFWTALQDLNSTGSFFWLSGDE 600
+ +C S +TI + EQ F+ S I + G +W L+D + W +G
Sbjct: 301 ATFEFVCGWLRSDFLTIYSAQEQEFIHSKIRALSKYGANWWIGLEDRRAGDQIHWSNGSP 360
Query: 601 VMYTHWNRDQPG---YSRGGCVALATGSAMGLWEVKNCT 636
V++ +W++ + G R CV ++ + GLW +NC+
Sbjct: 361 VIFQNWDKGRKGRMDSQRKRCVFMS--AITGLWGTENCS 397
Score = 64.8 bits (155), Expect = 7e-09
Identities = 87/423 (20%), Positives = 146/423 (33%), Gaps = 74/423 (17%)
Query: 1011 LVTITNPLEQAFITASLPNVTFD---LWIGLHASQR--DFQWV---EQEPLMYANWAPGE 1062
L+TIT+ EQAFIT+ + +V WI L ++ W ++EP+ Y +W +
Sbjct: 18 LLTITSRFEQAFITSLISSVARKDSYFWIALQDQNNTGEYTWKTMGQREPVQYTHWNAHQ 77
Query: 1063 PSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQ-----------KGT 1111
PS VVL S+ GRW+ ++C++ +C+ +G
Sbjct: 78 PSYHGGC----------VVLRGGSSF--GRWEVKNCSDFKAMSLCKTPIKVWEKTEFEGR 125
Query: 1112 DPSLSPSPAALPPAPGTELSYLNGTF---RLLQKPLRWHDALLLCESHNASLAYVPDPYT 1168
P P + T L+ F ++L K W +A CE A LA
Sbjct: 126 WPF---HPCYMDWESETGLASCFKVFHSEKVLMKR-SWREAEAFCEEFGAHLASFAHIEE 181
Query: 1169 QAFLTQAARGL-----RTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEP--------- 1214
+ F+ + WIG SW W DG P
Sbjct: 182 ENFVNKLLHSKFNWTQERQFWIGFNKRNPLNAGSWE---------WSDGSPVVSSFLDNA 232
Query: 1215 ---QQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGSCPQGLADSAWI 1271
+ C + ++C +K + +C + P + Y P W+
Sbjct: 233 YFEEDAKNCAVYKANNTLLPSNCASKHEW-ICKIPRDVKPNFPVWYQYDAP-------WL 284
Query: 1272 PFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLG 1331
++ Y FH C L+I E F+ +++ W+G
Sbjct: 285 FYQNAEYLFHTHPA-EWATFEFVCGWLRSDFLTIYSAQEQEFIHSKIRALSKYGANWWIG 343
Query: 1332 MNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGACTNITMGV 1391
+ G + W + + V + NW G C ++ + +GLW C ++ M
Sbjct: 344 LEDRRAGDQIHWSNGSPVIFQNWDKGRKGRMDSQRKRCVFMSAITGLWGTENC-SVPMPS 402
Query: 1392 VCK 1394
+CK
Sbjct: 403 ICK 405
Score = 48.8 bits (114), Expect = 4e-04
Identities = 81/408 (19%), Positives = 142/408 (33%), Gaps = 54/408 (13%)
Query: 860 LTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWT---DGSIINFISWAPG 916
L ++ S+ E F++ + +R ++ ++WI L + G + W + + W
Sbjct: 18 LLTITSRFEQAFITSLISSVAR-KDSYFWIALQDQNNTGEYTWKTMGQREPVQYTHWNAH 76
Query: 917 KPRPVGKDKKCVYMT--ASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPS 974
+P G CV + +S W + C ++ + + C
Sbjct: 77 QPSYHGG---CVVLRGGSSFGRWEVKNCSDFKAMSLCKTPIKVWEKTEFEGRWPFHPCYM 133
Query: 975 DWIQF--LNKCFQV-QGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLP--- 1028
DW L CF+V ++ + W EA+ CE+ A L + + E+ F+ L
Sbjct: 134 DWESETGLASCFKVFHSEKVLMKRSWREAEAFCEEFGAHLASFAHIEEENFVNKLLHSKF 193
Query: 1029 NVTFD--LWIGLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSG--------NKPTSC 1078
N T + WIG + ++ PL +W E S SP S +C
Sbjct: 194 NWTQERQFWIGFN---------KRNPLNAGSW---EWSDGSPVVSSFLDNAYFEEDAKNC 241
Query: 1079 AVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFR 1138
AV + + +C + H +IC+ D + P+ L Y N +
Sbjct: 242 AVYKANNTLL------PSNCASK-HEWICKIPRD--VKPNFPVWYQYDAPWLFYQNAEYL 292
Query: 1139 LLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLR---TPLWIGLAGEEGSRR 1195
P W +C + + Q F+ R L WIGL +
Sbjct: 293 FHTHPAEWATFEFVCGWLRSDFLTIYSAQEQEFIHSKIRALSKYGANWWIGLEDRRAGDQ 352
Query: 1196 YSWVSEEPLNYVGWQDGE----PQQPGGCTYVD-VDGAWRTTSCDTKL 1238
W + P+ + W G Q C ++ + G W T +C +
Sbjct: 353 IHWSNGSPVIFQNWDKGRKGRMDSQRKRCVFMSAITGLWGTENCSVPM 400
Score = 47.6 bits (111), Expect = 0.001
Identities = 51/210 (24%), Positives = 78/210 (36%), Gaps = 21/210 (10%)
Query: 1159 SLAYVPDPYTQAFLTQAARGLRTP---LWIGLAGEEGSRRYSWVS---EEPLNYVGWQDG 1212
+L + + QAF+T + WI L + + Y+W + EP+ Y W
Sbjct: 17 ALLTITSRFEQAFITSLISSVARKDSYFWIALQDQNNTGEYTWKTMGQREPVQYTHWNAH 76
Query: 1213 EPQQPGGCTYV---DVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGSCPQGLADSA 1269
+P GGC + G W +C ++C + + + G P
Sbjct: 77 QPSYHGGCVVLRGGSSFGRWEVKNCSDFKAMSLC--KTPIKVWEKTEFEGRWPFHPCYMD 134
Query: 1270 WIPFR--EHCYS-FHMELLL---GHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEG 1323
W C+ FH E +L +EA C+ G + S E FV + L S
Sbjct: 135 WESETGLASCFKVFHSEKVLMKRSWREAEAFCEEFGAHLASFAHIEEENFVNKLLHSKFN 194
Query: 1324 --QSRGAWLGMN-FNP-KGGTLVWQDNTAV 1349
Q R W+G N NP G+ W D + V
Sbjct: 195 WTQERQFWIGFNKRNPLNAGSWEWSDGSPV 224
>dbj|BAA06444.1| (D30780) phospholipase A2 receptor [Homo sapiens]
Length = 411
Score = 277 bits (701), Expect = 7e-73
Identities = 152/412 (36%), Positives = 223/412 (53%), Gaps = 30/412 (7%)
Query: 556 LVTITNRFEQAFVSSLIYN---WEGEYFWTALQDLNSTGSFFWL----SGDEVMYTHWNR 608
LVTITNRFEQAF++SLI + + YFW ALQD N TG + W + V YTHWN
Sbjct: 18 LVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNT 77
Query: 609 DQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGS 668
QP YS GGCVA+ +G WEVK+C F+A +C+Q + E P
Sbjct: 78 HQPRYS-GGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWPFHP---- 132
Query: 669 CPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLN 728
C W S+ L C+KVF SE++ K++W +A+ C+E GA L S A EEE+FV +L+
Sbjct: 133 CYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLH 192
Query: 729 KIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRGCAVL 788
F + E+ FWIG N+R+P SW WSD +F + + +D R CAV
Sbjct: 193 SKFNWT-----EERQFWIGFNKRNPLNAGSWEWSDRTPV-VSSFLDNTYFGEDARNCAVY 246
Query: 789 DLASLQWVAMQCDTQLDWICKIPRGTDVREP----DDSPQGRREWLRFQEAEYKFFEHHS 844
A+ + + C ++ +WICKIPR + P D P WL +Q+AEY F S
Sbjct: 247 K-ANKTLLPLHCGSKREWICKIPRDVKPKIPFWYQYDVP-----WLFYQDAEYLFHTFAS 300
Query: 845 TWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTD 904
W + +C+W ++L ++HS E +F+ ++ S+ WWIGL ++ FRW D
Sbjct: 301 EWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSK-YGASWWIGLQEERANDEFRWRD 359
Query: 905 GSIINFISWAPGKPRPV-GKDKKCVYMTASREDWGDQRCLTALPYICKRSNV 955
G+ + + +W G+ R V + ++C ++++ WG + C ++P ICKR V
Sbjct: 360 GTPVIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKRKKV 411
Score = 111 bits (275), Expect = 6e-23
Identities = 84/299 (28%), Positives = 127/299 (42%), Gaps = 29/299 (9%)
Query: 222 DERWGFCPIKSNDCETFWDKDQLTDSCYQ-FNFQSTL---SWREAWASCEQQGADLLSIT 277
+ERW F P C W+ + SC++ F+ + L +WREA A CE+ GA L S
Sbjct: 125 EERWPFHP-----CYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFA 179
Query: 278 EIHEQTYINGLLTGYSS-----TLWIGLNDLD--TSGGWQWSDNSPLKYLNWESDQPDNP 330
I E+ ++N LL + WIG N + +G W+WSD +P+ ++ +
Sbjct: 180 HIEEENFVNELLHSKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPV-VSSFLDNTYFGE 238
Query: 331 SEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPSWQPFQ 390
NC V + + C ++CK + +P P W V W +Q
Sbjct: 239 DARNCAVYKANKT--LLPLHCGSKREWICKIPRDV--KPKIPF-WYQYDVP----WLFYQ 289
Query: 391 GHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVE---ELWIGLNDL 447
Y W + C DL++IHS E EFI +IK + WIGL +
Sbjct: 290 DAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEE 349
Query: 448 KLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSICKK 506
+ F W DG+ V + +W + + C I G W C+ S+PSICK+
Sbjct: 350 RANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKR 408
Score = 75.7 bits (183), Expect = 4e-12
Identities = 86/394 (21%), Positives = 153/394 (38%), Gaps = 42/394 (10%)
Query: 273 LLSITEIHEQTYINGLLTGY----SSTLWIGLNDLDTSGGWQW----SDNSPLKYLNWES 324
L++IT EQ +I L++ S WI L D + +G + W P++Y +W +
Sbjct: 18 LVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNT 77
Query: 325 DQPDNPSEENCGVIR-TESSGGWQNRDC-SIALPYVCKKKPNATAEPTPPDRWANVKVEC 382
QP C +R G W+ + C +CK+ + +RW
Sbjct: 78 HQPRYSG--GCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWPFHPCYL 135
Query: 383 EPSWQPFQGHCYRL-----QAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQ-- 435
+ +P C+++ KR+W+E++ C G L S + E F+ + +
Sbjct: 136 DWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHSKF 195
Query: 436 ---EVEELWIGLNDLKLQMN---FEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEG 489
E + WIG N + +N +EWSD + V + + F + +C ++
Sbjct: 196 NWTEERQFWIGFNK-RNPLNAGSWEWSDRTPVVSSF---LDNTYFGEDARNC-AVYKANK 250
Query: 490 RWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLC 549
C ICK + + + W ++ + Y + +C
Sbjct: 251 TLLPLHCGSKREWICKIPRDV-KPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFEFVC 309
Query: 550 TDHGSQLVTITNRFEQAFVSSLI--YNWEGEYFWTALQDLNSTGSFFWLSGDEVMYTHWN 607
+ S L+TI + EQ F+ S I + G +W LQ+ + F W G V+Y +W+
Sbjct: 310 SWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWD 369
Query: 608 RDQP-----GYSRGGCVALATGSAMGLWEVKNCT 636
+ R G ++ S GLW + C+
Sbjct: 370 TGRERTVNNQSQRCGFIS----SITGLWGSEECS 399
Score = 70.6 bits (170), Expect = 1e-10
Identities = 36/116 (31%), Positives = 64/116 (55%), Gaps = 15/116 (12%)
Query: 252 NFQSTLSWREAWASCEQQGADLLSITEIHEQTYING---LLTGYSSTLWIGLNDLDTSGG 308
NF+ SW + DLL+I HEQ +I+ L+ Y ++ WIGL + +
Sbjct: 304 NFEFVCSWLHS---------DLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDE 354
Query: 309 WQWSDNSPLKYLNWES--DQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCKKK 362
++W D +P+ Y NW++ ++ N + CG I + +G W + +CS+++P +CK+K
Sbjct: 355 FRWRDGTPVIYQNWDTGRERTVNNQSQRCGFI-SSITGLWGSEECSVSMPSICKRK 409
Score = 62.1 bits (148), Expect = 5e-08
Identities = 89/423 (21%), Positives = 137/423 (32%), Gaps = 72/423 (17%)
Query: 1011 LVTITNPLEQAFITASLPNVT----FDLWIGLHASQR--DFQWV----EQEPLMYANWAP 1060
LVTITN EQAFIT+ + +V WI L ++ W + EP+ Y +W
Sbjct: 18 LVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNT 77
Query: 1061 GEP--SGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPS 1118
+P SG A G P GRW+ + C +C++ +
Sbjct: 78 HQPRYSGGCVAMRGRHPL--------------GRWEVKHCRHFKAMSLCKQPVENQEKAE 123
Query: 1119 PAALPPAPGTELSY-----LNGTFRLL--QKPLR---WHDALLLCESHNASLAYVPDPYT 1168
P L + L F++ +K L W +A CE A LA
Sbjct: 124 YEERWPFHPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEE 183
Query: 1169 QAFLTQAARGL-----RTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEP--------- 1214
+ F+ + WIG SW W D P
Sbjct: 184 ENFVNELLHSKFNWTEERQFWIGFNKRNPLNAGSWE---------WSDRTPVVSSFLDNT 234
Query: 1215 ---QQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGSCPQGLADSAWI 1271
+ C + C +K + +C + P Y P W+
Sbjct: 235 YFGEDARNCAVYKANKTLLPLHCGSKREW-ICKIPRDVKPKIPFWYQYDVP-------WL 286
Query: 1272 PFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLG 1331
+++ Y FH C +L+I E F+ +++ W+G
Sbjct: 287 FYQDAEYLFHT-FASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIG 345
Query: 1332 MNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGACTNITMGV 1391
+ W+D T V Y NW C +I S +GLW C +++M
Sbjct: 346 LQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEEC-SVSMPS 404
Query: 1392 VCK 1394
+CK
Sbjct: 405 ICK 407
Score = 49.6 bits (116), Expect = 3e-04
Identities = 78/408 (19%), Positives = 141/408 (34%), Gaps = 52/408 (12%)
Query: 860 LTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTD----GSIINFISWAP 915
L ++ ++ E F++ + + ++ ++WI L G + W + + W
Sbjct: 18 LVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNT 77
Query: 916 GKPRPVGKDKKCVYMTASRE--DWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCP 973
+PR G CV M W + C + V + + C
Sbjct: 78 HQPRYSGG---CVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWPFHPCY 134
Query: 974 SDWIQF--LNKCFQV-QGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLP-- 1028
DW L CF+V ++ + W EA+ CE+ A L + + E+ F+ L
Sbjct: 135 LDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHSK 194
Query: 1029 -NVTFD--LWIGLH----ASQRDFQWVEQEPLMYA---NWAPGEPSGPSPAPSGNKPTSC 1078
N T + WIG + + ++W ++ P++ + N GE + NK
Sbjct: 195 FNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYFGEDARNCAVYKANK---T 251
Query: 1079 AVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFR 1138
+ LH S W IC+ D + P L Y + +
Sbjct: 252 LLPLHCGSKR---EW------------ICKIPRD--VKPKIPFWYQYDVPWLFYQDAEYL 294
Query: 1139 LLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLR---TPLWIGLAGEEGSRR 1195
W + +C ++ L + + Q F+ + L WIGL E +
Sbjct: 295 FHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDE 354
Query: 1196 YSWVSEEPLNYVGWQDGEPQ----QPGGCTYV-DVDGAWRTTSCDTKL 1238
+ W P+ Y W G + Q C ++ + G W + C +
Sbjct: 355 FRWRDGTPVIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEECSVSM 402
>ref|XP_002319.1| lymphocyte antigen 75 [Homo sapiens]
Length = 385
Score = 270 bits (682), Expect = 1e-70
Identities = 143/387 (36%), Positives = 216/387 (54%), Gaps = 27/387 (6%)
Query: 343 SGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRS 402
SG WQ+ C LPYVC+K N T E T D W C+ W P G CY L E S
Sbjct: 5 SGLWQSFSCEAQLPYVCRKPLNNTVELT--DVWTYSDTRCDAGWLPNNGFCYLLVNESNS 62
Query: 403 WQESKKACLRGGGDLVSIHSMAELEFITKQIKQE--VEELWIGLNDLKLQMNFEWSDGSL 460
W ++ C DL+SIHS+A++E + ++ E EE+WIGL ++ + F+WSDG+
Sbjct: 63 WDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEEVWIGLKNINIPTLFQWSDGTE 122
Query: 461 VSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSICKKAGQ-LSQGAAEEDH 519
V+ T+W EPN + +CV+ G G+W C + L +CK+ G+ L+ ++++
Sbjct: 123 VTLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCEEKLKYVCKRKGEKLNDASSDKMC 182
Query: 520 GCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWE--- 576
+GW H +CY + ED+V + L TIT+RFEQ +++ L+ ++
Sbjct: 183 PPDEGWKRHGETCYKIYEDEVPFGTNCNL---------TITSRFEQEYLNDLMKKYDKSL 233
Query: 577 GEYFWTALQDLNSTGSFFWLS----GDEVMYTHWNRDQPGYSRGGCVALATGSAMGLWEV 632
+YFWT L+D++S G + W + V +++WN +P S GGCVA++TG ++G WEV
Sbjct: 234 RKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEPA-SPGGCVAMSTGKSVGKWEV 292
Query: 633 KNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQ 692
K+C SF+A IC++ G P+ PE P P CP+GW S CYKVF +ER+
Sbjct: 293 KDCRSFKALSICKKMSG-PLGPEEASPKP----DDPCPEGWQSFPASLSCYKVFHAERIV 347
Query: 693 DKKSWVQAQGACQELGAQLLSLASYEE 719
K++W +A+ CQ LGA L S + +E
Sbjct: 348 RKRNWEEAERFCQALGAHLSSFSHVDE 374
Score = 91.7 bits (224), Expect = 6e-17
Identities = 82/354 (23%), Positives = 130/354 (36%), Gaps = 51/354 (14%)
Query: 788 LDLASLQWVAMQCDTQLDWICKIPRGTDVREPD----DSPQGRREWLRFQEAEYKFFEHH 843
+D S W + C+ QL ++C+ P V D + WL Y
Sbjct: 1 MDAESGLWQSFSCEAQLPYVCRKPLNNTVELTDVWTYSDTRCDAGWLPNNGFCYLLVNES 60
Query: 844 STWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWT 903
++W +A C F ++L S+HS A+++ + L +E WIGL F+W+
Sbjct: 61 NSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEEV--WIGLKNINIPTLFQWS 118
Query: 904 DGSIINFISWAPGKPR-PVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQPP 962
DG+ + W +P P K CV W Q C L Y+CKR
Sbjct: 119 DGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCEEKLKYVCKRKGEKLNDASS 178
Query: 963 DLPTTALGGCPSD--WIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQ 1020
D CP D W + C+++ E + +TIT+ EQ
Sbjct: 179 DKM------CPPDEGWKRHGETCYKIYEDEVPFGTNCN-------------LTITSRFEQ 219
Query: 1021 AFITASLPNVTFDL----WIGLH--ASQRDFQWV----EQEPLMYANWAPGEPSGPSPAP 1070
++ + L W GL S ++ W + + ++NW EP+ P
Sbjct: 220 EYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEPASPG--- 276
Query: 1071 SGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPP 1124
C + S G+W+ + C IC+K + P L P A+ P
Sbjct: 277 ------GCVAMSTGKS---VGKWEVKDCRSFKALSICKKMSGP-LGPEEASPKP 320
Score = 90.1 bits (220), Expect = 2e-16
Identities = 99/419 (23%), Positives = 166/419 (38%), Gaps = 73/419 (17%)
Query: 489 GRWNDSPCNQSLPSICKK----AGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSE 544
G W C LP +C+K +L+ D C GW ++ CY L + ++ +
Sbjct: 6 GLWQSFSCEAQLPYVCRKPLNNTVELTDVWTYSDTRCDAGWLPNNGFCYLLVNESNSWDK 65
Query: 545 ARRLCTDHGSQLVTITNRFEQAFVSSLIYNWE-GEYFWTALQDLNSTGSFFWLSGDEVMY 603
A C S L++I + + V + ++N + E W L+++N F W G EV
Sbjct: 66 AHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEEVWIGLKNINIPTLFQWSDGTEVTL 125
Query: 604 THWNRDQPG--YSRG-GCVALATGSAMGLWEVKNCTSFRARYICR---QSLGTPVTPELP 657
T+W+ ++P Y++ CV+ +G W+V++C + +Y+C+ + L + ++
Sbjct: 126 TYWDENEPNVPYNKTPNCVSYL--GELGQWKVQSCEE-KLKYVCKRKGEKLNDASSDKMC 182
Query: 658 GPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASY 717
PD +GW + CYK++ E V C L++ S
Sbjct: 183 PPD----------EGWKRHGET--CYKIYEDE--------VPFGTNCN------LTITSR 216
Query: 718 EEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDG----VGFSYHNFD 773
E+ ++ +++ K + + +FW GL D G +W G V FS NF
Sbjct: 217 FEQEYLNDLMKKY------DKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFL 270
Query: 774 RSRHDDDDIRGCAVLDLASL--QWVAMQCDT-QLDWICKI---PRGTDVREP---DDSPQ 824
GC + +W C + + ICK P G + P D P+
Sbjct: 271 EPASPG----GCVAMSTGKSVGKWEVKDCRSFKALSICKKMSGPLGPEEASPKPDDPCPE 326
Query: 825 GRREWLRFQEAE--YKFFE-----HHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNL 876
G W F + YK F W +A+R C A L+S E+ H L
Sbjct: 327 G---WQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFL 382
Score = 84.7 bits (206), Expect = 7e-15
Identities = 86/344 (25%), Positives = 147/344 (42%), Gaps = 55/344 (15%)
Query: 248 CYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTG--YSSTLWIGLNDLDT 305
CY +S SW +A A C+ +DL+SI + + + L +WIGL +++
Sbjct: 53 CYLLVNESN-SWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEEVWIGLKNINI 111
Query: 306 SGGWQWSDNSPLKYLNWESDQPDNPSEE--NCGVIRTESSGGWQNRDCSIALPYVCKKKP 363
+QWSD + + W+ ++P+ P + NC V G W+ + C L YVCK+K
Sbjct: 112 PTLFQWSDGTEVTLTYWDENEPNVPYNKTPNC-VSYLGELGQWKVQSCEEKLKYVCKRKG 170
Query: 364 N-----ATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLV 418
++ + PPD W+ CY++ ++ + G +
Sbjct: 171 EKLNDASSDKMCPPDE----------GWKRHGETCYKIYEDEVPF---------GTNCNL 211
Query: 419 SIHSMAELEFITKQIKQEVEEL----WIGLNDLKLQMNFEWSD----GSLVSFTHWHPFE 470
+I S E E++ +K+ + L W GL D+ + W+ V+F++W+ E
Sbjct: 212 TITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLE 271
Query: 471 PNNFRDSLEDCVTIWGPE--GRWNDSPCNQ-SLPSICKK-AGQL--SQGAAEEDHGCRKG 524
P S CV + + G+W C SICKK +G L + + + D C +G
Sbjct: 272 P----ASPGGCVAMSTGKSVGKWEVKDCRSFKALSICKKMSGPLGPEEASPKPDDPCPEG 327
Query: 525 WTWH--SPSCYWLGEDQ-----VTYSEARRLCTDHGSQLVTITN 561
W S SCY + + + EA R C G+ L + ++
Sbjct: 328 WQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSH 371
Score = 80.4 bits (195), Expect = 1e-13
Identities = 100/409 (24%), Positives = 172/409 (41%), Gaps = 63/409 (15%)
Query: 628 GLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFS 687
GLW+ +C + + Y+CR+ L V EL D C GW + +CY +
Sbjct: 6 GLWQSFSCEA-QLPYVCRKPLNNTV--ELT--DVWTYSDTRCDAGWLPNNG--FCYLL-- 56
Query: 688 SERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIG 747
+ + SW +A C+ + L+S+ S + V L+ +I E+ WIG
Sbjct: 57 ---VNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHN------EDIKEE--VWIG 105
Query: 748 LNRRDPRGGQSWRWSDG--VGFSYHNFDRSRHDDDDIRGCAVLDLASL-QWVAMQCDTQL 804
L ++ ++WSDG V +Y + + + C V L L QW C+ +L
Sbjct: 106 L--KNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNC-VSYLGELGQWKVQSCEEKL 162
Query: 805 DWICKIPRGTDVREPDDSPQGRRE--WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTS 862
++CK +G + + + W R E YK +E + + +
Sbjct: 163 KYVCK-RKGEKLNDASSDKMCPPDEGWKRHGETCYKIYEDEVPFGTNCNL---------T 212
Query: 863 VHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRW-TDGS---IINFISWAPGKP 918
+ S+ E ++L+ ++K+ ++ +++W GL +S G + W T G + F +W +P
Sbjct: 213 ITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEP 272
Query: 919 RPVGKDKKCVYMTASRE----DWGDQRCLTALPYICKRSN---VTKETQP-PDLPTTALG 970
G CV M+ + + D R AL ICK+ + +E P PD P
Sbjct: 273 ASPG---GCVAMSTGKSVGKWEVKDCRSFKALS-ICKKMSGPLGPEEASPKPDDP----- 323
Query: 971 GCPSDWIQF--LNKCFQVQGQEPQSRVK-WSEAQFSCEQQEAQLVTITN 1016
CP W F C++V E R + W EA+ C+ A L + ++
Sbjct: 324 -CPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSH 371
Score = 70.6 bits (170), Expect = 1e-10
Identities = 57/184 (30%), Positives = 83/184 (44%), Gaps = 34/184 (18%)
Query: 274 LSITEIHEQTYINGLLTGYSSTL----WIGLNDLDTSGGWQWSD----NSPLKYLNWESD 325
L+IT EQ Y+N L+ Y +L W GL D+D+ G + W+ + + NW
Sbjct: 211 LTITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFL 270
Query: 326 QPDNPSEENCGVIRT-ESSGGWQNRDC-SIALPYVCKKKPNAT----AEPTPPDRWANVK 379
+P +P C + T +S G W+ +DC S +CKK A P P D
Sbjct: 271 EPASPG--GCVAMSTGKSVGKWEVKDCRSFKALSICKKMSGPLGPEEASPKPDD------ 322
Query: 380 VECEPSWQPFQGH--CYRL-QAE----KRSWQESKKACLRGGGDLVSIHSMAE----LEF 428
C WQ F CY++ AE KR+W+E+++ C G L S + E L F
Sbjct: 323 -PCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHF 381
Query: 429 ITKQ 432
+T Q
Sbjct: 382 LTDQ 385
Score = 44.9 bits (104), Expect = 0.007
Identities = 71/341 (20%), Positives = 122/341 (34%), Gaps = 40/341 (11%)
Query: 1090 TGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYL--NG-TFRLLQKPLRW 1146
+G W SC E ++C+K + ++ + + +L NG + L+ + W
Sbjct: 5 SGLWQSFSC-EAQLPYVCRKPLNNTVELTDVWTYSDTRCDAGWLPNNGFCYLLVNESNSW 63
Query: 1147 HDALLLCESHNASLAYVPD-PYTQAFLTQAAR-GLRTPLWIGLAGEEGSRRYSWVSEEPL 1204
A C++ ++ L + + +T+ ++ +WIGL + W +
Sbjct: 64 DKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEEVWIGLKNINIPTLFQWSDGTEV 123
Query: 1205 NYVGWQDGEP-----QQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHG 1259
W + EP + P +Y+ G W+ SC+ KL+ VC S
Sbjct: 124 TLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCEEKLK-YVC--KRKGEKLNDASSDK 180
Query: 1260 SCPQGLADSAWIPFREHCYS-FHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHL 1318
CP D W E CY + E+ G C L+I E ++ + +
Sbjct: 181 MCP---PDEGWKRHGETCYKIYEDEVPFG-----TNCN------LTITSRFEQEYLNDLM 226
Query: 1319 QSYEGQSRG-AWLGMNFNPKGGTLVWQD----NTAVNYSNWGPPGLGPSMLSHNSCYWIQ 1373
+ Y+ R W G+ G W AV +SNW L P+ S C +
Sbjct: 227 KKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWN--FLEPA--SPGGCVAMS 282
Query: 1374 SNS--GLWRPGACTNITMGVVCKLPRAEQSSFSPSALPENP 1412
+ G W C + +CK S P++P
Sbjct: 283 TGKSVGKWEVKDCRSFKALSICKKMSGPLGPEEASPKPDDP 323
>gb|AAA29218.2| (L22612) tyrosine kinase receptor [Hydra vulgaris]
Length = 1348
Score = 192 bits (482), Expect = 3e-47
Identities = 155/605 (25%), Positives = 248/605 (40%), Gaps = 97/605 (16%)
Query: 232 SNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTG 291
SN C+ W + + +Q SWR+A SC+ LLSI + E +I +L
Sbjct: 19 SNSCDNGWLEYKAFCYLFQNKTLKAKSWRDASLSCQAFDGHLLSIEDQAENFFILNILKD 78
Query: 292 ---YSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN-PSEENCGVIRTESSGGWQ 347
WIGLND + ++WSD+ ++ NW +P+N SEENC +S GW
Sbjct: 79 SRMQKDNYWIGLNDASNNREFRWSDDKTPQFFNWLPKKPNNVESEENC---VEANSMGWN 135
Query: 348 NRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKR-----S 402
+ C ++CK + CE W ++ +CY Q + +
Sbjct: 136 DNKCGATNGFICKIR-------------KEYNDFCEDGWLNYKNYCYFFQNQNEQFDGSN 182
Query: 403 WQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVS 462
W +S +C GG+L+S+ E FIT +++ WIGLN L F WSD S
Sbjct: 183 WTDSYLSCRFKGGNLLSVEDQEENSFITSVLEKYSTFFWIGLNYLMSYKRFVWSDNS--- 239
Query: 463 FTHWHP--------FEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGA 514
+W+P N+F + CV I WN C KK G + +
Sbjct: 240 --NWNPKILIENTLHPSNDFSMKIARCVVINALS--WNIQNCK-------KKNGYICKVK 288
Query: 515 AEEDHGCRKGWTWHSPSCYWLGEDQVT----YSEARRLCTDHGSQLVTITNRFEQAFVSS 570
E + C K W + +CY+ T +S A C + G L++I ++ E AF+ +
Sbjct: 289 RENNTNCSKYWFQYGMNCYYFQNTNNTIRRSWSWAYISCLEKGGNLLSIEDKAENAFILN 348
Query: 571 LIYNWEG--EYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQPGYSRGGCVALATGSAMG 628
++ N+ + +W L D F W + Y+ + + CV +
Sbjct: 349 ILKNYSSSTDNYWIGLTDDWYNSWFLWSDNTYIQYSKF-KTLLDTEIEMCVIM----TKL 403
Query: 629 LWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSS 688
WE +NC R+IC+ T C +GW S YCY ++S
Sbjct: 404 YWETENC-YLSHRFICKVKRAT---------------NEYCAEGWTS--YRIYCYFIYSI 445
Query: 689 ERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGL 748
E W ++ +CQ +G LLS+ + EE F+ N L I + +WIGL
Sbjct: 446 E-----FDWFKSFSSCQNIGGNLLSIENQEENRFIENDL----------IKDNDKYWIGL 490
Query: 749 NR---RDPRGGQSWRWSDGVGFSYHNFDRSRHDDDD-IRGCAVLDLASLQWVAMQCDTQL 804
N+ + + + WSD + N+ ++ D+++ I C ++ W +C
Sbjct: 491 NKIWNDYLKKNKRFEWSDNTYTQFFNWITNQPDNNNGIESCVEMNYNG--WSDKECKVLN 548
Query: 805 DWICK 809
+ICK
Sbjct: 549 GFICK 553
Score = 173 bits (435), Expect = 1e-41
Identities = 149/603 (24%), Positives = 240/603 (39%), Gaps = 88/603 (14%)
Query: 378 VKVECEPSWQPFQGHCYRLQ---AEKRSWQESKKACLRGGGDLVSIHSMAELEFIT---K 431
V C+ W ++ CY Q + +SW+++ +C G L+SI AE FI K
Sbjct: 18 VSNSCDNGWLEYKAFCYLFQNKTLKAKSWRDASLSCQAFDGHLLSIEDQAENFFILNILK 77
Query: 432 QIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRW 491
+ + + WIGLND F WSD F +W P +PNN +S E+CV W
Sbjct: 78 DSRMQKDNYWIGLNDASNNREFRWSDDKTPQFFNWLPKKPNNV-ESEENCVE--ANSMGW 134
Query: 492 NDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGE-----DQVTYSEAR 546
ND+ C + ICK E + C GW + CY+ D ++++
Sbjct: 135 NDNKCGATNGFICKI-------RKEYNDFCEDGWLNYKNYCYFFQNQNEQFDGSNWTDSY 187
Query: 547 RLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGD----EVM 602
C G L+++ ++ E +F++S++ + +FW L L S F W +++
Sbjct: 188 LSCRFKGGNLLSVEDQEENSFITSVLEKY-STFFWIGLNYLMSYKRFVWSDNSNWNPKIL 246
Query: 603 YTHWNRDQPGYSR--GGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPD 660
+ +S CV + S W ++NC + YIC+
Sbjct: 247 IENTLHPSNDFSMKIARCVVINALS----WNIQNCKK-KNGYICKVKREN---------- 291
Query: 661 PTPSLTGSCPQGWASDTKLRY---CYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASY 717
+C + W +Y CY F + ++SW A +C E G LLS+
Sbjct: 292 -----NTNCSKYW-----FQYGMNCY-YFQNTNNTIRRSWSWAYISCLEKGGNLLSIEDK 340
Query: 718 EEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRH 777
E F+ N+L ++ +WIGL D + WSD Y F
Sbjct: 341 AENAFILNILKNYSSSTDN-------YWIGLT--DDWYNSWFLWSDNTYIQYSKFKTLL- 390
Query: 778 DDDDIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEY 837
D +I C + + L W C +ICK+ R T+ + +G W ++ Y
Sbjct: 391 -DTEIEMCVI--MTKLYWETENCYLSHRFICKVKRATN----EYCAEG---WTSYRIYCY 440
Query: 838 KFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESD 897
+ W ++ C L S+ +Q E F+ ++L K +WIGL+ +D
Sbjct: 441 FIYSIEFDWFKSFSSCQNIGGNLLSIENQEENRFIENDLIK----DNDKYWIGLNKIWND 496
Query: 898 -----GRFRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKR 952
RF W+D + F +W +P + CV M + W D+ C +ICK
Sbjct: 497 YLKKNKRFEWSDNTYTQFFNWITNQPDNNNGIESCVEM--NYNGWSDKECKVLNGFICKT 554
Query: 953 SNV 955
V
Sbjct: 555 KKV 557
Score = 150 bits (374), Expect = 1e-34
Identities = 141/584 (24%), Positives = 238/584 (40%), Gaps = 74/584 (12%)
Query: 829 WLRFQEAEYKFFEHH---STWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQ 885
WL ++ Y F +W A C F L S+ QAE +F N+ K SR Q+
Sbjct: 26 WLEYKAFCYLFQNKTLKAKSWRDASLSCQAFDGHLLSIEDQAE-NFFILNILKDSRMQKD 84
Query: 886 HWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTA 945
++WIGL+ + ++ FRW+D F +W P KP V ++ CV A+ W D +C
Sbjct: 85 NYWIGLNDASNNREFRWSDDKTPQFFNWLPKKPNNVESEENCV--EANSMGWNDNKCGAT 142
Query: 946 LPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQ-SRVKWSEAQFSC 1004
+ICK + KE C W+ + N C+ Q Q Q W+++ SC
Sbjct: 143 NGFICK---IRKEYN---------DFCEDGWLNYKNYCYFFQNQNEQFDGSNWTDSYLSC 190
Query: 1005 EQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLH--ASQRDFQWVEQEPLMYANWAPGE 1062
+ L+++ + E +FIT+ L + WIGL+ S + F W + +NW P
Sbjct: 191 RFKGGNLLSVEDQEENSFITSVLEKYSTFFWIGLNYLMSYKRFVWSDN-----SNWNPKI 245
Query: 1063 PSGPSPAPSGNKPTSCA--VVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPA 1120
+ PS + A VV+++ S W+ ++C ++ +G+IC+ + + + S
Sbjct: 246 LIENTLHPSNDFSMKIARCVVINALS------WNIQNC-KKKNGYICKVKRENNTNCSKY 298
Query: 1121 ALPPAPGTELSYLNGTFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLR 1180
G Y T +++ W A + C +L + D AF+ +
Sbjct: 299 WF--QYGMNCYYFQNTNNTIRRSWSW--AYISCLEKGGNLLSIEDKAENAFILNILKNYS 354
Query: 1181 TP---LWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTK 1237
+ WIGL + + + W + Y ++ + C + W T +C
Sbjct: 355 SSTDNYWIGLTDDWYNSWFLWSDNTYIQYSKFKTLLDTEIEMCV-IMTKLYWETENCYLS 413
Query: 1238 LQGAVCGVSSGPPPPRRISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQR 1297
+C V + + + C +G W +R +CY F + ++ CQ
Sbjct: 414 -HRFICKV--------KRATNEYCAEG-----WTSYRIYCY-FIYSIEFDWFKSFSSCQN 458
Query: 1298 AGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMN-----FNPKGGTLVWQDNTAVNYS 1352
GG +LSI ++ EN F+ L + W+G+N + K W DNT +
Sbjct: 459 IGGNLLSIENQEENRFIENDLIK---DNDKYWIGLNKIWNDYLKKNKRFEWSDNTYTQFF 515
Query: 1353 NW--GPPGLGPSMLSHNSCYWIQSNSGLWRPGACTNITMGVVCK 1394
NW P + SC ++ N W C + G +CK
Sbjct: 516 NWITNQPDNNNGI---ESC--VEMNYNGWSDKEC-KVLNGFICK 553
Score = 131 bits (325), Expect = 8e-29
Identities = 117/450 (26%), Positives = 185/450 (41%), Gaps = 75/450 (16%)
Query: 228 CPIKS--ND-CETFWDKDQLTDSCYQFNFQSTL----SWREAWASCEQQGADLLSITEIH 280
C I+ ND CE W + + CY F Q+ +W +++ SC +G +LLS+ +
Sbjct: 147 CKIRKEYNDFCEDGWLNYK--NYCYFFQNQNEQFDGSNWTDSYLSCRFKGGNLLSVEDQE 204
Query: 281 EQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWES----DQPDNPSEE--- 333
E ++I +L YS+ WIGLN L + + WSDNS NW + +PS +
Sbjct: 205 ENSFITSVLEKYSTFFWIGLNYLMSYKRFVWSDNS-----NWNPKILIENTLHPSNDFSM 259
Query: 334 ---NCGVIRTESSGGWQNRDCSIALPYVCK-KKPNATAEPTPPDRWANVKVECEPSWQPF 389
C VI S W ++C Y+CK K+ N T C W +
Sbjct: 260 KIARCVVINALS---WNIQNCKKKNGYICKVKRENNT--------------NCSKYWFQY 302
Query: 390 QGHCYRLQ----AEKRSWQESKKACLRGGGDLVSIHSMAELEF---ITKQIKQEVEELWI 442
+CY Q +RSW + +CL GG+L+SI AE F I K + WI
Sbjct: 303 GMNCYYFQNTNNTIRRSWSWAYISCLEKGGNLLSIEDKAENAFILNILKNYSSSTDNYWI 362
Query: 443 GLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPS 502
GL D F WSD + + ++ + +E CV + + W C S
Sbjct: 363 GLTDDWYNSWFLWSDNTYIQYSKFKTL----LDTEIEMCVIM--TKLYWETENCYLSHRF 416
Query: 503 ICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNR 562
ICK ++ C +GWT + CY++ + + ++ C + G L++I N+
Sbjct: 417 ICKVKRATNE-------YCAEGWTSYRIYCYFIYSIEFDWFKSFSSCQNIGGNLLSIENQ 469
Query: 563 FEQAFVSSLIYNWEGEYFWTALQD-----LNSTGSFFWLSGDEVMYTHWNRDQPGYSRG- 616
E F+ + + + + +W L L F W + +W +QP + G
Sbjct: 470 EENRFIENDLIK-DNDKYWIGLNKIWNDYLKKNKRFEWSDNTYTQFFNWITNQPDNNNGI 528
Query: 617 -GCVALATGSAMGLWEVKNCTSFRARYICR 645
CV + W K C +IC+
Sbjct: 529 ESCVEMNYNG----WSDKECKVLNG-FICK 553
Score = 71.0 bits (171), Expect = 9e-11
Identities = 38/121 (31%), Positives = 65/121 (53%), Gaps = 10/121 (8%)
Query: 248 CYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLND----- 302
CY F + W ++++SC+ G +LLSI E +I L + WIGLN
Sbjct: 439 CY-FIYSIEFDWFKSFSSCQNIGGNLLSIENQEENRFIENDLIKDNDKYWIGLNKIWNDY 497
Query: 303 LDTSGGWQWSDNSPLKYLNWESDQPDNPSE-ENCGVIRTESSGGWQNRDCSIALPYVCKK 361
L + ++WSDN+ ++ NW ++QPDN + E+C + + GW +++C + ++CK
Sbjct: 498 LKKNKRFEWSDNTYTQFFNWITNQPDNNNGIESCVEM---NYNGWSDKECKVLNGFICKT 554
Query: 362 K 362
K
Sbjct: 555 K 555
Score = 64.8 bits (155), Expect = 7e-09
Identities = 40/139 (28%), Positives = 64/139 (45%), Gaps = 7/139 (5%)
Query: 1267 DSAWIPFREHCYSFHMELLLGH--KEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQ 1324
D+ W+ ++ CY F + L ++A CQ G +LSI D+ EN F+ L+ Q
Sbjct: 23 DNGWLEYKAFCYLFQNKTLKAKSWRDASLSCQAFDGHLLSIEDQAENFFILNILKDSRMQ 82
Query: 1325 SRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGAC 1384
W+G+N W D+ + NW P ++ S +C +++NS W C
Sbjct: 83 KDNYWIGLNDASNNREFRWSDDKTPQFFNWLPKKPN-NVESEENC--VEANSMGWNDNKC 139
Query: 1385 TNITMGVVCKLPRAEQSSF 1403
T G +CK+ R E + F
Sbjct: 140 -GATNGFICKI-RKEYNDF 156
>gb|AAC51365.1| (U58856) unknown [Homo sapiens]
Length = 401
Score = 189 bits (475), Expect = 2e-46
Identities = 100/125 (80%), Positives = 103/125 (82%), Gaps = 1/125 (0%)
Query: 1355 GPPGLGPSMLSHNSCYWIQSNSGLWRPGACTNITMGVVCKLPRAEQSSFSPSALPENPAA 1414
G PGLGP NSGLWRPGACTNITMGVVCKLPRAEQ+ P + PAA
Sbjct: 97 GAPGLGPQHAEPQQLLLDSDNSGLWRPGACTNITMGVVCKLPRAEQTLL-PISASRKPAA 155
Query: 1415 LVVVLMAVLLLLALLTAALILYRRRQSIERGAFEGARYSRSSSSPTEATEKNILVSDMEM 1474
LVVVLMAVLLLLALLTAALILYRRRQ+IERGAFEGARYSRSSSSPTEATEKNILVSDMEM
Sbjct: 156 LVVVLMAVLLLLALLTAALILYRRRQNIERGAFEGARYSRSSSSPTEATEKNILVSDMEM 215
Query: 1475 NEQQE 1479
NEQQE
Sbjct: 216 NEQQE 220
>ref|NP_031450.1| aggrecan, structural proteoglycan of cartilage [Mus musculus]
sp|Q61282|PGCA_MOUSE AGGRECAN CORE PROTEIN PRECURSOR (CARTILAGE-SPECIFIC PROTEOGLYCAN CORE
PROTEIN) (CSPCP)
pir||A55182 aggrecan precursor - mouse
gb|AAC37670.1| (L07049) aggrecan [Mus musculus]
Length = 2132
Score = 124 bits (308), Expect = 8e-27
Identities = 73/231 (31%), Positives = 111/231 (47%), Gaps = 25/231 (10%)
Query: 281 EQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNW-ESDQPDNPSEENCGVIR 339
++T I+G + ++S + + ++ T W P + L ES P EE
Sbjct: 1834 DRTEISGEWSDHTSEVNVAISSTITESEWAQPTRYPTETLQEIESPNPSYSGEET----- 1888
Query: 340 TESSGGWQNRDCSIAL---PYVCKKKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRL 396
Q + +++L P + + + E T D+ +CE W FQGHCYR
Sbjct: 1889 -------QTAETTMSLTDAPTLSSSEGSGETESTVADQ-----EQCEEGWTKFQGHCYRH 1936
Query: 397 QAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWS 456
++ +W ++++ C L SI + E EF+ K + + WIGLND ++ +F WS
Sbjct: 1937 FPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQ---DYQWIGLNDRTIEGDFRWS 1993
Query: 457 DGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSLPSICKK 506
DG + F W P +P+NF + EDCV IW G WND PCN LP CKK
Sbjct: 1994 DGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPCNYQLPFTCKK 2044
Score = 85.8 bits (209), Expect = 3e-15
Identities = 48/137 (35%), Positives = 68/137 (49%), Gaps = 8/137 (5%)
Query: 235 CETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSS 294
CE W K Q CY+ +F +W +A C +Q + L SI EQ ++N Y
Sbjct: 1922 CEEGWTKFQ--GHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQ- 1977
Query: 295 TLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTESSGGWQNRDCS 352
WIGLND G ++WSD L++ W +QPDN + E+C V+ G W + C+
Sbjct: 1978 --WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPCN 2035
Query: 353 IALPYVCKKKPNATAEP 369
LP+ CKK A +P
Sbjct: 2036 YQLPFTCKKGTVACGDP 2052
Score = 84.7 bits (206), Expect = 7e-15
Identities = 47/139 (33%), Positives = 67/139 (47%), Gaps = 13/139 (9%)
Query: 821 DSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFS 880
D Q W +FQ Y+ F TW A+R C Q+ L+S+ + E +F++ N Q +
Sbjct: 1918 DQEQCEEGWTKFQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQ 1977
Query: 881 RAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR---PVGKDKKCVYMT-ASRED 936
WIGL+ +G FRW+DG + F W P +P G+D CV M R +
Sbjct: 1978 -------WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGED--CVVMIWHERGE 2028
Query: 937 WGDQRCLTALPYICKRSNV 955
W D C LP+ CK+ V
Sbjct: 2029 WNDVPCNYQLPFTCKKGTV 2047
Score = 61.7 bits (147), Expect = 6e-08
Identities = 38/142 (26%), Positives = 61/142 (42%), Gaps = 19/142 (13%)
Query: 972 CPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT 1031
C W +F C++ R W +A+ C +Q++ L +I P EQ F+ + +
Sbjct: 1922 CEEGWTKFQGHCYR----HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQ 1977
Query: 1032 FDLWIGLH--ASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHF 1089
WIGL+ + DF+W + L + W P +P C V++ H
Sbjct: 1978 ---WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGE-----DCVVMIW----HE 2025
Query: 1090 TGRWDDRSCTEETHGFICQKGT 1111
G W+D C + F C+KGT
Sbjct: 2026 RGEWNDVPCNYQL-PFTCKKGT 2046
Score = 59.7 bits (142), Expect = 2e-07
Identities = 45/145 (31%), Positives = 71/145 (48%), Gaps = 27/145 (18%)
Query: 669 CPQGWASDTKLR-YCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANML 727
C +GW TK + +CY+ F D+++WV A+ C+E + L S+ + EE+ FV
Sbjct: 1922 CEEGW---TKFQGHCYRHFP-----DRETWVDAERRCREQQSHLSSIVTPEEQEFV---- 1969
Query: 728 NKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--C 785
NK + Q + WIGLN R G +RWSDG + + ++ D+ G C
Sbjct: 1970 NK---------NAQDYQWIGLNDRTIEG--DFRWSDGHSLQFEKWRPNQPDNFFATGEDC 2018
Query: 786 AVLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ QL + CK
Sbjct: 2019 VVMIWHERGEWNDVPCNYQLPFTCK 2043
Score = 58.6 bits (139), Expect = 5e-07
Identities = 36/142 (25%), Positives = 61/142 (42%), Gaps = 8/142 (5%)
Query: 507 AGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQA 566
+G+ A+++ C +GWT CY D+ T+ +A R C + S L +I EQ
Sbjct: 1909 SGETESTVADQEQ-CEEGWTKFQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQE 1967
Query: 567 FVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG--YSRGGCVALATG 624
FV+ +Y W L D G F W G + + W +QP ++ G +
Sbjct: 1968 FVNKNAQ----DYQWIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVMIW 2023
Query: 625 SAMGLWEVKNCTSFRARYICRQ 646
G W C +++ + C++
Sbjct: 2024 HERGEWNDVPC-NYQLPFTCKK 2044
Score = 46.5 bits (108), Expect = 0.002
Identities = 33/133 (24%), Positives = 50/133 (36%), Gaps = 9/133 (6%)
Query: 1263 QGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYE 1322
Q + W F+ HCY H +A +RC+ + SI+ E FV ++ Q Y+
Sbjct: 1919 QEQCEEGWTKFQGHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQ 1977
Query: 1323 GQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YWIQSNSGLWRP 1381
W+G+N G W D ++ + W P + C I G W
Sbjct: 1978 ------WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWND 2031
Query: 1382 GACTNITMGVVCK 1394
C N + CK
Sbjct: 2032 VPC-NYQLPFTCK 2043
>ref|XP_007701.1| aggrecan 1, isoform 1 precursor [Homo sapiens]
Length = 2360
Score = 123 bits (305), Expect = 2e-26
Identities = 79/242 (32%), Positives = 117/242 (47%), Gaps = 19/242 (7%)
Query: 267 EQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLK-YLNWESD 325
E G + T ++T I+G L+G++S L + ++ W P + +L ES
Sbjct: 2109 EAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESS 2168
Query: 326 QPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPS 385
EE V S D SI K++ +TA A+ +V CE
Sbjct: 2169 SLLYSGEETHTVETATSP-----TDASIPASPEWKRESESTA--------ADQEV-CEEG 2214
Query: 386 WQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIGLN 445
W +QGHCYR ++ +W ++++ C L SI + E EF+ + + WIGLN
Sbjct: 2215 WNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQ---DYQWIGLN 2271
Query: 446 DLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSLPSIC 504
D ++ +F WSDG + F +W P +P+NF + EDCV IW +G WND PCN LP C
Sbjct: 2272 DRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTC 2331
Query: 505 KK 506
KK
Sbjct: 2332 KK 2333
Score = 89.7 bits (219), Expect = 2e-16
Identities = 47/129 (36%), Positives = 68/129 (52%), Gaps = 8/129 (6%)
Query: 235 CETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSS 294
CE W+K Q CY+ +F +W +A C +Q + L SI EQ ++N Y
Sbjct: 2211 CEEGWNKYQ--GHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ- 2266
Query: 295 TLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTESSGGWQNRDCS 352
WIGLND G ++WSD P+++ NW +QPDN + E+C V+ G W + C+
Sbjct: 2267 --WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCN 2324
Query: 353 IALPYVCKK 361
LP+ CKK
Sbjct: 2325 YHLPFTCKK 2333
Score = 80.4 bits (195), Expect = 1e-13
Identities = 47/156 (30%), Positives = 75/156 (47%), Gaps = 18/156 (11%)
Query: 810 IPRGTDVREPDDSPQGRRE-----WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVH 864
IP + + +S +E W ++Q Y+ F TW A+R C Q+ L+S+
Sbjct: 2191 IPASPEWKRESESTAADQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIV 2250
Query: 865 SQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR---PV 921
+ E +F+++N Q + WIGL+ +G FRW+DG + F +W P +P
Sbjct: 2251 TPEEQEFVNNNAQDYQ-------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAA 2303
Query: 922 GKDKKCVYMT-ASREDWGDQRCLTALPYICKRSNVT 956
G+D CV M + +W D C LP+ CK+ T
Sbjct: 2304 GED--CVVMIWHEKGEWNDVPCNYHLPFTCKKGTAT 2337
Score = 64.8 bits (155), Expect = 7e-09
Identities = 39/142 (27%), Positives = 63/142 (43%), Gaps = 19/142 (13%)
Query: 972 CPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT 1031
C W ++ C++ R W +A+ C +Q++ L +I P EQ F+ + +
Sbjct: 2211 CEEGWNKYQGHCYR----HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ 2266
Query: 1032 FDLWIGLH--ASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHF 1089
WIGL+ + DF+W + P+ + NW P +P A C V++ H
Sbjct: 2267 ---WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGE-----DCVVMIW----HE 2314
Query: 1090 TGRWDDRSCTEETHGFICQKGT 1111
G W+D C F C+KGT
Sbjct: 2315 KGEWNDVPCNYHL-PFTCKKGT 2335
Score = 64.0 bits (153), Expect = 1e-08
Identities = 41/159 (25%), Positives = 69/159 (42%), Gaps = 8/159 (5%)
Query: 494 SPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHG 553
SP + S+P+ + + S+ A + C +GW + CY D+ T+ +A R C +
Sbjct: 2185 SPTDASIPASPEWKRE-SESTAADQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQ 2243
Query: 554 SQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG- 612
S L +I EQ FV+ N +Y W L D G F W G + + +W +QP
Sbjct: 2244 SHLSSIVTPEEQEFVN----NNAQDYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDN 2299
Query: 613 -YSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGT 650
++ G + G W C ++ + C++ T
Sbjct: 2300 FFAAGEDCVVMIWHEKGEWNDVPC-NYHLPFTCKKGTAT 2337
Score = 59.3 bits (141), Expect = 3e-07
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 25/144 (17%)
Query: 669 CPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLN 728
C +GW + +CY+ F D+++WV A+ C+E + L S+ + EE+ FV N
Sbjct: 2211 CEEGW--NKYQGHCYRHFP-----DRETWVDAERRCREQQSHLSSIVTPEEQEFVNN--- 2260
Query: 729 KIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--CA 786
+ Q + WIGLN R G +RWSDG + N+ ++ D+ G C
Sbjct: 2261 ----------NAQDYQWIGLNDRTIEG--DFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 2308
Query: 787 VLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ L + CK
Sbjct: 2309 VMIWHEKGEWNDVPCNYHLPFTCK 2332
Score = 48.8 bits (114), Expect = 4e-04
Identities = 36/146 (24%), Positives = 55/146 (37%), Gaps = 9/146 (6%)
Query: 1250 PPPRRISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEM 1309
P +R S + Q + + W ++ HCY H +A +RC+ + SI+
Sbjct: 2195 PEWKRESESTAADQEVCEEGWNKYQGHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPE 2253
Query: 1310 ENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC 1369
E FV + Q Y+ W+G+N G W D + + NW P + C
Sbjct: 2254 EQEFVNNNAQDYQ------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDC 2307
Query: 1370 -YWIQSNSGLWRPGACTNITMGVVCK 1394
I G W C N + CK
Sbjct: 2308 VVMIWHEKGEWNDVPC-NYHLPFTCK 2332
Score = 36.4 bits (82), Expect = 2.5
Identities = 32/158 (20%), Positives = 56/158 (35%), Gaps = 34/158 (21%)
Query: 1074 KPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELS-- 1131
+P + + S S ++G EETH + + SP+ A++P +P +
Sbjct: 2157 RPAETHLEIESSSLLYSG--------EETHT------VETATSPTDASIPASPEWKRESE 2202
Query: 1132 ---------------YLNGTFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAA 1176
Y +R W DA C + L+ + P Q F+ A
Sbjct: 2203 STAADQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNA 2262
Query: 1177 RGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEP 1214
+ + WIGL + W P+ + W+ +P
Sbjct: 2263 QDYQ---WIGLNDRTIEGDFRWSDGHPMQFENWRPNQP 2297
>gb|AAC25581.1| (AC005254) PGCN_HUMAN, PARTIAL CDS; 245 KD EARLY POSTNATAL CORE
GLYCOPROTEIN [Homo sapiens]
Length = 315
Score = 123 bits (305), Expect = 2e-26
Identities = 56/126 (44%), Positives = 77/126 (60%), Gaps = 4/126 (3%)
Query: 382 CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELW 441
C+ W FQGHCYR A +R+W++++K C R G L S+HS E FI E W
Sbjct: 82 CDRGWHKFQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFIN---SFGHENTW 138
Query: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPE-GRWNDSPCNQSL 500
IGLND ++ +F+W+D + + F +W +P+NF EDCV + E GRWND PCN +L
Sbjct: 139 IGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPCNYNL 198
Query: 501 PSICKK 506
P +CKK
Sbjct: 199 PYVCKK 204
Score = 95.2 bits (233), Expect = 5e-18
Identities = 53/151 (35%), Positives = 76/151 (50%), Gaps = 12/151 (7%)
Query: 213 CATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGAD 272
C YG FC + C+ W K Q CY++ F +W +A C ++
Sbjct: 64 CLCLPSYGGS----FCEKDTEGCDRGWHKFQ--GHCYRY-FAHRRAWEDAEKDCRRRSGH 116
Query: 273 LLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--P 330
L S+ E ++IN G+ +T WIGLND +QW+DN+ L++ NW +QPDN
Sbjct: 117 LTSVHSPEEHSFINSF--GHENT-WIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFA 173
Query: 331 SEENCGVIRTESSGGWQNRDCSIALPYVCKK 361
E+C V+ SG W + C+ LPYVCKK
Sbjct: 174 GGEDCVVMVAHESGRWNDVPCNYNLPYVCKK 204
Score = 75.7 bits (183), Expect = 4e-12
Identities = 44/133 (33%), Positives = 63/133 (47%), Gaps = 13/133 (9%)
Query: 827 REWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQH 886
R W +FQ Y++F H W A++ C LTSVHS E F+ + ++
Sbjct: 84 RGWHKFQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFI-------NSFGHEN 136
Query: 887 WWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPV---GKDKKCVYMTASRED-WGDQRC 942
WIGL+ + F+WTD + + F +W +P G+D CV M A W D C
Sbjct: 137 TWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGED--CVVMVAHESGRWNDVPC 194
Query: 943 LTALPYICKRSNV 955
LPY+CK+ V
Sbjct: 195 NYNLPYVCKKGTV 207
Score = 67.5 bits (162), Expect = 1e-09
Identities = 41/143 (28%), Positives = 65/143 (44%), Gaps = 19/143 (13%)
Query: 971 GCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNV 1030
GC W +F C++ R W +A+ C ++ L ++ +P E +FI +
Sbjct: 81 GCDRGWHKFQGHCYRYFAH----RRAWEDAEKDCRRRSGHLTSVHSPEEHSFINSFGHEN 136
Query: 1031 TFDLWIGLHAS--QRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAH 1088
T WIGL+ +RDFQW + L + NW +P C V++ AH
Sbjct: 137 T---WIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGE-----DCVVMV----AH 184
Query: 1089 FTGRWDDRSCTEETHGFICQKGT 1111
+GRW+D C ++C+KGT
Sbjct: 185 ESGRWNDVPCNYNL-PYVCKKGT 206
Score = 51.2 bits (120), Expect = 9e-05
Identities = 47/201 (23%), Positives = 80/201 (39%), Gaps = 24/201 (11%)
Query: 516 EEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNW 575
++ GC +GW CY + + +A + C L ++ + E +F++S +
Sbjct: 77 KDTEGCDRGWHKFQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFINSFGH-- 134
Query: 576 EGEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQP-GYSRGG--CVALATGSAMGLWEV 632
E W L D F W + + +W +QP + GG CV + + G W
Sbjct: 135 --ENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHES-GRWND 191
Query: 633 KNCTSFRARYICRQSLGTPVTPELPGPDP---TPSLTGSCPQGWASDTKLRY-CYKVFSS 688
C ++ Y+C++ GT L GP P SL G+ + +RY C + F+
Sbjct: 192 VPC-NYNLPYVCKK--GT----VLCGPPPAVENASLIGARKAKYNVHATVRYQCNEGFAQ 244
Query: 689 E-----RLQDKKSWVQAQGAC 704
R + W + Q C
Sbjct: 245 HHVATIRCRSNGKWDRPQIVC 265
Score = 47.6 bits (111), Expect = 0.001
Identities = 37/143 (25%), Positives = 57/143 (38%), Gaps = 12/143 (8%)
Query: 1256 SYHGS-CPQGL--ADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENV 1312
SY GS C + D W F+ HCY + ++A + C+R G + S+ E+
Sbjct: 69 SYGGSFCEKDTEGCDRGWHKFQGHCYRYFAHRR-AWEDAEKDCRRRSGHLTSVHSPEEHS 127
Query: 1313 FVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YW 1371
F+ S+ ++ W+G+N W DNT + + NW C
Sbjct: 128 FI----NSFGHEN--TWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVM 181
Query: 1372 IQSNSGLWRPGACTNITMGVVCK 1394
+ SG W C N + VCK
Sbjct: 182 VAHESGRWNDVPC-NYNLPYVCK 203
Score = 40.2 bits (92), Expect = 0.17
Identities = 41/170 (24%), Positives = 57/170 (33%), Gaps = 25/170 (14%)
Query: 1097 SCTEETHGFICQKGTDPSLSPSPAALPPAPGTE------LSYLNGTFRLLQKPLRWHDAL 1150
+C +E +GF+C PS TE + +R W DA
Sbjct: 54 TCIDEVNGFVCL------CLPSYGGSFCEKDTEGCDRGWHKFQGHCYRYFAHRRAWEDAE 107
Query: 1151 LLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQ 1210
C + L V P +F+ WIGL R + W L + W+
Sbjct: 108 KDCRRRSGHLTSVHSPEEHSFINSFGH---ENTWIGLNDRIVERDFQWTDNTGLQFENWR 164
Query: 1211 DGEPQQ--PGG--CTYV--DVDGAWRTTSCDTKLQGAVC---GVSSGPPP 1251
+ +P GG C + G W C+ L VC V GPPP
Sbjct: 165 ENQPDNFFAGGEDCVVMVAHESGRWNDVPCNYNLP-YVCKKGTVLCGPPP 213
>ref|NP_004377.1| chondroitin sulfate proteoglycan 3 (neurocan) [Homo sapiens]
gb|AAC80576.1| (AF026547) neurocan [Homo sapiens]
Length = 1321
Score = 123 bits (305), Expect = 2e-26
Identities = 56/126 (44%), Positives = 77/126 (60%), Gaps = 4/126 (3%)
Query: 382 CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELW 441
C+ W FQGHCYR A +R+W++++K C R G L S+HS E FI E W
Sbjct: 1088 CDRGWHKFQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFIN---SFGHENTW 1144
Query: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPE-GRWNDSPCNQSL 500
IGLND ++ +F+W+D + + F +W +P+NF EDCV + E GRWND PCN +L
Sbjct: 1145 IGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPCNYNL 1204
Query: 501 PSICKK 506
P +CKK
Sbjct: 1205 PYVCKK 1210
Score = 95.2 bits (233), Expect = 5e-18
Identities = 53/151 (35%), Positives = 76/151 (50%), Gaps = 12/151 (7%)
Query: 213 CATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGAD 272
C YG FC + C+ W K Q CY++ F +W +A C ++
Sbjct: 1070 CLCLPSYGGS----FCEKDTEGCDRGWHKFQ--GHCYRY-FAHRRAWEDAEKDCRRRSGH 1122
Query: 273 LLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--P 330
L S+ E ++IN G+ +T WIGLND +QW+DN+ L++ NW +QPDN
Sbjct: 1123 LTSVHSPEEHSFINSF--GHENT-WIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFA 1179
Query: 331 SEENCGVIRTESSGGWQNRDCSIALPYVCKK 361
E+C V+ SG W + C+ LPYVCKK
Sbjct: 1180 GGEDCVVMVAHESGRWNDVPCNYNLPYVCKK 1210
Score = 75.7 bits (183), Expect = 4e-12
Identities = 44/133 (33%), Positives = 63/133 (47%), Gaps = 13/133 (9%)
Query: 827 REWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQH 886
R W +FQ Y++F H W A++ C LTSVHS E F+ + ++
Sbjct: 1090 RGWHKFQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFI-------NSFGHEN 1142
Query: 887 WWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPV---GKDKKCVYMTASRED-WGDQRC 942
WIGL+ + F+WTD + + F +W +P G+D CV M A W D C
Sbjct: 1143 TWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGED--CVVMVAHESGRWNDVPC 1200
Query: 943 LTALPYICKRSNV 955
LPY+CK+ V
Sbjct: 1201 NYNLPYVCKKGTV 1213
Score = 67.5 bits (162), Expect = 1e-09
Identities = 41/143 (28%), Positives = 65/143 (44%), Gaps = 19/143 (13%)
Query: 971 GCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNV 1030
GC W +F C++ R W +A+ C ++ L ++ +P E +FI +
Sbjct: 1087 GCDRGWHKFQGHCYRYFAH----RRAWEDAEKDCRRRSGHLTSVHSPEEHSFINSFGHEN 1142
Query: 1031 TFDLWIGLHAS--QRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAH 1088
T WIGL+ +RDFQW + L + NW +P C V++ AH
Sbjct: 1143 T---WIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGE-----DCVVMV----AH 1190
Query: 1089 FTGRWDDRSCTEETHGFICQKGT 1111
+GRW+D C ++C+KGT
Sbjct: 1191 ESGRWNDVPCNYNL-PYVCKKGT 1212
Score = 48.8 bits (114), Expect = 4e-04
Identities = 36/149 (24%), Positives = 62/149 (41%), Gaps = 15/149 (10%)
Query: 516 EEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNW 575
++ GC +GW CY + + +A + C L ++ + E +F++S +
Sbjct: 1083 KDTEGCDRGWHKFQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFINSFGH-- 1140
Query: 576 EGEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQP-GYSRGG--CVALATGSAMGLWEV 632
E W L D F W + + +W +QP + GG CV + + G W
Sbjct: 1141 --ENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHES-GRWND 1197
Query: 633 KNCTSFRARYICRQSLGTPVTPELPGPDP 661
C ++ Y+C++ GT L GP P
Sbjct: 1198 VPC-NYNLPYVCKK--GT----VLCGPPP 1219
Score = 47.6 bits (111), Expect = 0.001
Identities = 37/143 (25%), Positives = 57/143 (38%), Gaps = 12/143 (8%)
Query: 1256 SYHGS-CPQGL--ADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENV 1312
SY GS C + D W F+ HCY + ++A + C+R G + S+ E+
Sbjct: 1075 SYGGSFCEKDTEGCDRGWHKFQGHCYRYFAHRR-AWEDAEKDCRRRSGHLTSVHSPEEHS 1133
Query: 1313 FVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YW 1371
F+ S+ ++ W+G+N W DNT + + NW C
Sbjct: 1134 FI----NSFGHEN--TWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVM 1187
Query: 1372 IQSNSGLWRPGACTNITMGVVCK 1394
+ SG W C N + VCK
Sbjct: 1188 VAHESGRWNDVPC-NYNLPYVCK 1209
Score = 40.2 bits (92), Expect = 0.17
Identities = 41/170 (24%), Positives = 57/170 (33%), Gaps = 25/170 (14%)
Query: 1097 SCTEETHGFICQKGTDPSLSPSPAALPPAPGTE------LSYLNGTFRLLQKPLRWHDAL 1150
+C +E +GF+C PS TE + +R W DA
Sbjct: 1060 TCIDEVNGFVCL------CLPSYGGSFCEKDTEGCDRGWHKFQGHCYRYFAHRRAWEDAE 1113
Query: 1151 LLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQ 1210
C + L V P +F+ WIGL R + W L + W+
Sbjct: 1114 KDCRRRSGHLTSVHSPEEHSFINSFGH---ENTWIGLNDRIVERDFQWTDNTGLQFENWR 1170
Query: 1211 DGEPQQ--PGG--CTYV--DVDGAWRTTSCDTKLQGAVC---GVSSGPPP 1251
+ +P GG C + G W C+ L VC V GPPP
Sbjct: 1171 ENQPDNFFAGGEDCVVMVAHESGRWNDVPCNYNLP-YVCKKGTVLCGPPP 1219
>ref|NP_001126.1| aggrecan 1, isoform 1 precursor; Aggrecan-1 (chondroitin sulfate
proteoglycan-1, large aggregating proteoglycan, antigen
identifies by monoclonal antibody A0122); chondroitin
sulfate proteoglycan 1, large aggregating proteoglycan
[Homo sapiens]
gb|AAA62824.1| (M55172) large aggregating cartilage proteoglycan core protein [Homo
sapiens]
Length = 2316
Score = 123 bits (305), Expect = 2e-26
Identities = 79/242 (32%), Positives = 117/242 (47%), Gaps = 19/242 (7%)
Query: 267 EQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLK-YLNWESD 325
E G + T ++T I+G L+G++S L + ++ W P + +L ES
Sbjct: 2065 EAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESS 2124
Query: 326 QPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPS 385
EE V S D SI K++ +TA A+ +V CE
Sbjct: 2125 SLLYSGEETHTVETATSP-----TDASIPASPEWKRESESTA--------ADQEV-CEEG 2170
Query: 386 WQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIGLN 445
W +QGHCYR ++ +W ++++ C L SI + E EF+ + + WIGLN
Sbjct: 2171 WNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQ---DYQWIGLN 2227
Query: 446 DLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSLPSIC 504
D ++ +F WSDG + F +W P +P+NF + EDCV IW +G WND PCN LP C
Sbjct: 2228 DRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTC 2287
Query: 505 KK 506
KK
Sbjct: 2288 KK 2289
Score = 89.7 bits (219), Expect = 2e-16
Identities = 47/129 (36%), Positives = 68/129 (52%), Gaps = 8/129 (6%)
Query: 235 CETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSS 294
CE W+K Q CY+ +F +W +A C +Q + L SI EQ ++N Y
Sbjct: 2167 CEEGWNKYQ--GHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ- 2222
Query: 295 TLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTESSGGWQNRDCS 352
WIGLND G ++WSD P+++ NW +QPDN + E+C V+ G W + C+
Sbjct: 2223 --WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCN 2280
Query: 353 IALPYVCKK 361
LP+ CKK
Sbjct: 2281 YHLPFTCKK 2289
Score = 80.4 bits (195), Expect = 1e-13
Identities = 47/156 (30%), Positives = 75/156 (47%), Gaps = 18/156 (11%)
Query: 810 IPRGTDVREPDDSPQGRRE-----WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVH 864
IP + + +S +E W ++Q Y+ F TW A+R C Q+ L+S+
Sbjct: 2147 IPASPEWKRESESTAADQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIV 2206
Query: 865 SQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR---PV 921
+ E +F+++N Q + WIGL+ +G FRW+DG + F +W P +P
Sbjct: 2207 TPEEQEFVNNNAQDYQ-------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAA 2259
Query: 922 GKDKKCVYMT-ASREDWGDQRCLTALPYICKRSNVT 956
G+D CV M + +W D C LP+ CK+ T
Sbjct: 2260 GED--CVVMIWHEKGEWNDVPCNYHLPFTCKKGTAT 2293
Score = 64.8 bits (155), Expect = 7e-09
Identities = 39/142 (27%), Positives = 63/142 (43%), Gaps = 19/142 (13%)
Query: 972 CPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT 1031
C W ++ C++ R W +A+ C +Q++ L +I P EQ F+ + +
Sbjct: 2167 CEEGWNKYQGHCYR----HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ 2222
Query: 1032 FDLWIGLH--ASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHF 1089
WIGL+ + DF+W + P+ + NW P +P A C V++ H
Sbjct: 2223 ---WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGE-----DCVVMIW----HE 2270
Query: 1090 TGRWDDRSCTEETHGFICQKGT 1111
G W+D C F C+KGT
Sbjct: 2271 KGEWNDVPCNYHL-PFTCKKGT 2291
Score = 64.0 bits (153), Expect = 1e-08
Identities = 41/159 (25%), Positives = 69/159 (42%), Gaps = 8/159 (5%)
Query: 494 SPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHG 553
SP + S+P+ + + S+ A + C +GW + CY D+ T+ +A R C +
Sbjct: 2141 SPTDASIPASPEWKRE-SESTAADQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQ 2199
Query: 554 SQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG- 612
S L +I EQ FV+ N +Y W L D G F W G + + +W +QP
Sbjct: 2200 SHLSSIVTPEEQEFVN----NNAQDYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDN 2255
Query: 613 -YSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGT 650
++ G + G W C ++ + C++ T
Sbjct: 2256 FFAAGEDCVVMIWHEKGEWNDVPC-NYHLPFTCKKGTAT 2293
Score = 59.3 bits (141), Expect = 3e-07
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 25/144 (17%)
Query: 669 CPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLN 728
C +GW + +CY+ F D+++WV A+ C+E + L S+ + EE+ FV N
Sbjct: 2167 CEEGW--NKYQGHCYRHFP-----DRETWVDAERRCREQQSHLSSIVTPEEQEFVNN--- 2216
Query: 729 KIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--CA 786
+ Q + WIGLN R G +RWSDG + N+ ++ D+ G C
Sbjct: 2217 ----------NAQDYQWIGLNDRTIEG--DFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 2264
Query: 787 VLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ L + CK
Sbjct: 2265 VMIWHEKGEWNDVPCNYHLPFTCK 2288
Score = 48.8 bits (114), Expect = 4e-04
Identities = 36/146 (24%), Positives = 55/146 (37%), Gaps = 9/146 (6%)
Query: 1250 PPPRRISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEM 1309
P +R S + Q + + W ++ HCY H +A +RC+ + SI+
Sbjct: 2151 PEWKRESESTAADQEVCEEGWNKYQGHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPE 2209
Query: 1310 ENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC 1369
E FV + Q Y+ W+G+N G W D + + NW P + C
Sbjct: 2210 EQEFVNNNAQDYQ------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDC 2263
Query: 1370 -YWIQSNSGLWRPGACTNITMGVVCK 1394
I G W C N + CK
Sbjct: 2264 VVMIWHEKGEWNDVPC-NYHLPFTCK 2288
Score = 36.4 bits (82), Expect = 2.5
Identities = 32/158 (20%), Positives = 56/158 (35%), Gaps = 34/158 (21%)
Query: 1074 KPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELS-- 1131
+P + + S S ++G EETH + + SP+ A++P +P +
Sbjct: 2113 RPAETHLEIESSSLLYSG--------EETHT------VETATSPTDASIPASPEWKRESE 2158
Query: 1132 ---------------YLNGTFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAA 1176
Y +R W DA C + L+ + P Q F+ A
Sbjct: 2159 STAADQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNA 2218
Query: 1177 RGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEP 1214
+ + WIGL + W P+ + W+ +P
Sbjct: 2219 QDYQ---WIGLNDRTIEGDFRWSDGHPMQFENWRPNQP 2253
>pir||A39086 aggrecan precursor - human
Length = 2316
Score = 123 bits (305), Expect = 2e-26
Identities = 79/242 (32%), Positives = 117/242 (47%), Gaps = 19/242 (7%)
Query: 267 EQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLK-YLNWESD 325
E G + T ++T I+G L+G++S L + ++ W P + +L ES
Sbjct: 2065 EAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESS 2124
Query: 326 QPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPS 385
EE V S D SI K++ +TA A+ +V CE
Sbjct: 2125 SLLYSGEETHTVETATSP-----TDASIPASPEWKRESESTA--------ADQEV-CEEG 2170
Query: 386 WQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIGLN 445
W +QGHCYR ++ +W ++++ C L SI + E EF+ + + WIGLN
Sbjct: 2171 WNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQ---DYQWIGLN 2227
Query: 446 DLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSLPSIC 504
D ++ +F WSDG + F +W P +P+NF + EDCV IW +G WND PCN LP C
Sbjct: 2228 DRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTC 2287
Query: 505 KK 506
KK
Sbjct: 2288 KK 2289
Score = 89.7 bits (219), Expect = 2e-16
Identities = 47/129 (36%), Positives = 68/129 (52%), Gaps = 8/129 (6%)
Query: 235 CETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSS 294
CE W+K Q CY+ +F +W +A C +Q + L SI EQ ++N Y
Sbjct: 2167 CEEGWNKYQ--GHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ- 2222
Query: 295 TLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTESSGGWQNRDCS 352
WIGLND G ++WSD P+++ NW +QPDN + E+C V+ G W + C+
Sbjct: 2223 --WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCN 2280
Query: 353 IALPYVCKK 361
LP+ CKK
Sbjct: 2281 YHLPFTCKK 2289
Score = 80.4 bits (195), Expect = 1e-13
Identities = 47/156 (30%), Positives = 75/156 (47%), Gaps = 18/156 (11%)
Query: 810 IPRGTDVREPDDSPQGRRE-----WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVH 864
IP + + +S +E W ++Q Y+ F TW A+R C Q+ L+S+
Sbjct: 2147 IPASPEWKRESESTAADQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIV 2206
Query: 865 SQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR---PV 921
+ E +F+++N Q + WIGL+ +G FRW+DG + F +W P +P
Sbjct: 2207 TPEEQEFVNNNAQDYQ-------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAA 2259
Query: 922 GKDKKCVYMT-ASREDWGDQRCLTALPYICKRSNVT 956
G+D CV M + +W D C LP+ CK+ T
Sbjct: 2260 GED--CVVMIWHEKGEWNDVPCNYHLPFTCKKGTAT 2293
Score = 64.8 bits (155), Expect = 7e-09
Identities = 39/142 (27%), Positives = 63/142 (43%), Gaps = 19/142 (13%)
Query: 972 CPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT 1031
C W ++ C++ R W +A+ C +Q++ L +I P EQ F+ + +
Sbjct: 2167 CEEGWNKYQGHCYR----HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ 2222
Query: 1032 FDLWIGLH--ASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHF 1089
WIGL+ + DF+W + P+ + NW P +P A C V++ H
Sbjct: 2223 ---WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGE-----DCVVMIW----HE 2270
Query: 1090 TGRWDDRSCTEETHGFICQKGT 1111
G W+D C F C+KGT
Sbjct: 2271 KGEWNDVPCNYHL-PFTCKKGT 2291
Score = 64.0 bits (153), Expect = 1e-08
Identities = 41/159 (25%), Positives = 69/159 (42%), Gaps = 8/159 (5%)
Query: 494 SPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHG 553
SP + S+P+ + + S+ A + C +GW + CY D+ T+ +A R C +
Sbjct: 2141 SPTDASIPASPEWKRE-SESTAADQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQ 2199
Query: 554 SQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG- 612
S L +I EQ FV+ N +Y W L D G F W G + + +W +QP
Sbjct: 2200 SHLSSIVTPEEQEFVN----NNAQDYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDN 2255
Query: 613 -YSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGT 650
++ G + G W C ++ + C++ T
Sbjct: 2256 FFAAGEDCVVMIWHEKGEWNDVPC-NYHLPFTCKKGTAT 2293
Score = 59.3 bits (141), Expect = 3e-07
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 25/144 (17%)
Query: 669 CPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLN 728
C +GW + +CY+ F D+++WV A+ C+E + L S+ + EE+ FV N
Sbjct: 2167 CEEGW--NKYQGHCYRHFP-----DRETWVDAERRCREQQSHLSSIVTPEEQEFVNN--- 2216
Query: 729 KIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--CA 786
+ Q + WIGLN R G +RWSDG + N+ ++ D+ G C
Sbjct: 2217 ----------NAQDYQWIGLNDRTIEG--DFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 2264
Query: 787 VLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ L + CK
Sbjct: 2265 VMIWHEKGEWNDVPCNYHLPFTCK 2288
Score = 48.8 bits (114), Expect = 4e-04
Identities = 36/146 (24%), Positives = 55/146 (37%), Gaps = 9/146 (6%)
Query: 1250 PPPRRISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEM 1309
P +R S + Q + + W ++ HCY H +A +RC+ + SI+
Sbjct: 2151 PEWKRESESTAADQEVCEEGWNKYQGHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPE 2209
Query: 1310 ENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC 1369
E FV + Q Y+ W+G+N G W D + + NW P + C
Sbjct: 2210 EQEFVNNNAQDYQ------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDC 2263
Query: 1370 -YWIQSNSGLWRPGACTNITMGVVCK 1394
I G W C N + CK
Sbjct: 2264 VVMIWHEKGEWNDVPC-NYHLPFTCK 2288
Score = 36.4 bits (82), Expect = 2.5
Identities = 32/158 (20%), Positives = 56/158 (35%), Gaps = 34/158 (21%)
Query: 1074 KPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELS-- 1131
+P + + S S ++G EETH + + SP+ A++P +P +
Sbjct: 2113 RPAETHLEIESSSLLYSG--------EETHT------VETATSPTDASIPASPEWKRESE 2158
Query: 1132 ---------------YLNGTFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAA 1176
Y +R W DA C + L+ + P Q F+ A
Sbjct: 2159 STAADQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNA 2218
Query: 1177 RGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEP 1214
+ + WIGL + W P+ + W+ +P
Sbjct: 2219 QDYQ---WIGLNDRTIEGDFRWSDGHPMQFENWRPNQP 2253
>pir||S62786 aggrecan - human (fragment)
emb|CAA35463.1| (X17406) cartilage specific proteoglycan (600 AA) [Homo sapiens]
Length = 600
Score = 123 bits (305), Expect = 2e-26
Identities = 79/242 (32%), Positives = 117/242 (47%), Gaps = 19/242 (7%)
Query: 267 EQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLK-YLNWESD 325
E G + T ++T I+G L+G++S L + ++ W P + +L ES
Sbjct: 288 EAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESS 347
Query: 326 QPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPS 385
EE V S D SI K++ +TA A+ +V CE
Sbjct: 348 SLLYSGEETHTVETATSP-----TDASIPASPEWKRESESTA--------ADQEV-CEEG 393
Query: 386 WQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIGLN 445
W +QGHCYR ++ +W ++++ C L SI + E EF+ + + WIGLN
Sbjct: 394 WNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQ---DYQWIGLN 450
Query: 446 DLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSLPSIC 504
D ++ +F WSDG + F +W P +P+NF + EDCV IW +G WND PCN LP C
Sbjct: 451 DRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTC 510
Query: 505 KK 506
KK
Sbjct: 511 KK 512
Score = 93.2 bits (228), Expect = 2e-17
Identities = 50/137 (36%), Positives = 71/137 (51%), Gaps = 8/137 (5%)
Query: 235 CETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSS 294
CE W+K Q CY+ +F +W +A C +Q + L SI EQ ++N Y
Sbjct: 390 CEEGWNKYQ--GHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ- 445
Query: 295 TLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTESSGGWQNRDCS 352
WIGLND G ++WSD P+++ NW +QPDN + E+C V+ G W + C+
Sbjct: 446 --WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCN 503
Query: 353 IALPYVCKKKPNATAEP 369
LP+ CKK A EP
Sbjct: 504 YHLPFTCKKGTVACGEP 520
Score = 80.0 bits (194), Expect = 2e-13
Identities = 47/155 (30%), Positives = 75/155 (48%), Gaps = 18/155 (11%)
Query: 810 IPRGTDVREPDDSPQGRRE-----WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVH 864
IP + + +S +E W ++Q Y+ F TW A+R C Q+ L+S+
Sbjct: 370 IPASPEWKRESESTAADQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIV 429
Query: 865 SQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR---PV 921
+ E +F+++N Q + WIGL+ +G FRW+DG + F +W P +P
Sbjct: 430 TPEEQEFVNNNAQDYQ-------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAA 482
Query: 922 GKDKKCVYMT-ASREDWGDQRCLTALPYICKRSNV 955
G+D CV M + +W D C LP+ CK+ V
Sbjct: 483 GED--CVVMIWHEKGEWNDVPCNYHLPFTCKKGTV 515
Score = 64.8 bits (155), Expect = 7e-09
Identities = 39/142 (27%), Positives = 63/142 (43%), Gaps = 19/142 (13%)
Query: 972 CPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT 1031
C W ++ C++ R W +A+ C +Q++ L +I P EQ F+ + +
Sbjct: 390 CEEGWNKYQGHCYR----HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ 445
Query: 1032 FDLWIGLH--ASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHF 1089
WIGL+ + DF+W + P+ + NW P +P A C V++ H
Sbjct: 446 ---WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGE-----DCVVMIW----HE 493
Query: 1090 TGRWDDRSCTEETHGFICQKGT 1111
G W+D C F C+KGT
Sbjct: 494 KGEWNDVPCNYHL-PFTCKKGT 514
Score = 63.2 bits (151), Expect = 2e-08
Identities = 44/166 (26%), Positives = 72/166 (42%), Gaps = 10/166 (6%)
Query: 494 SPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHG 553
SP + S+P+ + + S+ A + C +GW + CY D+ T+ +A R C +
Sbjct: 364 SPTDASIPASPEWKRE-SESTAADQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQ 422
Query: 554 SQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG- 612
S L +I EQ FV+ N +Y W L D G F W G + + +W +QP
Sbjct: 423 SHLSSIVTPEEQEFVN----NNAQDYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDN 478
Query: 613 -YSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELP 657
++ G + G W C ++ + C++ GT E P
Sbjct: 479 FFAAGEDCVVMIWHEKGEWNDVPC-NYHLPFTCKK--GTVACGEPP 521
Score = 59.3 bits (141), Expect = 3e-07
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 25/144 (17%)
Query: 669 CPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLN 728
C +GW + +CY+ F D+++WV A+ C+E + L S+ + EE+ FV N
Sbjct: 390 CEEGW--NKYQGHCYRHFP-----DRETWVDAERRCREQQSHLSSIVTPEEQEFVNN--- 439
Query: 729 KIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--CA 786
+ Q + WIGLN R G +RWSDG + N+ ++ D+ G C
Sbjct: 440 ----------NAQDYQWIGLNDRTIEG--DFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 487
Query: 787 VLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ L + CK
Sbjct: 488 VMIWHEKGEWNDVPCNYHLPFTCK 511
Score = 48.8 bits (114), Expect = 4e-04
Identities = 36/146 (24%), Positives = 55/146 (37%), Gaps = 9/146 (6%)
Query: 1250 PPPRRISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEM 1309
P +R S + Q + + W ++ HCY H +A +RC+ + SI+
Sbjct: 374 PEWKRESESTAADQEVCEEGWNKYQGHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPE 432
Query: 1310 ENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC 1369
E FV + Q Y+ W+G+N G W D + + NW P + C
Sbjct: 433 EQEFVNNNAQDYQ------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDC 486
Query: 1370 -YWIQSNSGLWRPGACTNITMGVVCK 1394
I G W C N + CK
Sbjct: 487 VVMIWHEKGEWNDVPC-NYHLPFTCK 511
Score = 36.4 bits (82), Expect = 2.5
Identities = 32/158 (20%), Positives = 56/158 (35%), Gaps = 34/158 (21%)
Query: 1074 KPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELS-- 1131
+P + + S S ++G EETH + + SP+ A++P +P +
Sbjct: 336 RPAETHLEIESSSLLYSG--------EETHT------VETATSPTDASIPASPEWKRESE 381
Query: 1132 ---------------YLNGTFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAA 1176
Y +R W DA C + L+ + P Q F+ A
Sbjct: 382 STAADQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNA 441
Query: 1177 RGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEP 1214
+ + WIGL + W P+ + W+ +P
Sbjct: 442 QDYQ---WIGLNDRTIEGDFRWSDGHPMQFENWRPNQP 476
>gb|AAD24546.2| (AF116856) neurocan core protein precursor [Gallus gallus]
Length = 1290
Score = 121 bits (301), Expect = 5e-26
Identities = 55/126 (43%), Positives = 78/126 (61%), Gaps = 4/126 (3%)
Query: 382 CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELW 441
C+ +W FQGHCYR + +RSW+++++ C R G L SIHS E FI E W
Sbjct: 1056 CDHNWHKFQGHCYRYFSRRRSWEDAERDCRRRAGHLTSIHSQEEHGFIN---SFGHENTW 1112
Query: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPE-GRWNDSPCNQSL 500
IGLND ++ +F+W+D + + + +W +P+NF EDCV + E G+WND PCN +L
Sbjct: 1113 IGLNDRIVEQDFQWTDNTGLQYENWRENQPDNFFAGGEDCVVLVSHEIGKWNDVPCNYNL 1172
Query: 501 PSICKK 506
P ICKK
Sbjct: 1173 PYICKK 1178
Score = 92.4 bits (226), Expect = 3e-17
Identities = 50/136 (36%), Positives = 71/136 (51%), Gaps = 8/136 (5%)
Query: 228 CPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYING 287
C + C+ W K Q CY++ F SW +A C ++ L SI E +IN
Sbjct: 1049 CEKDTEGCDHNWHKFQ--GHCYRY-FSRRRSWEDAERDCRRRAGHLTSIHSQEEHGFINS 1105
Query: 288 LLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTESSGG 345
G+ +T WIGLND +QW+DN+ L+Y NW +QPDN E+C V+ + G
Sbjct: 1106 F--GHENT-WIGLNDRIVEQDFQWTDNTGLQYENWRENQPDNFFAGGEDCVVLVSHEIGK 1162
Query: 346 WQNRDCSIALPYVCKK 361
W + C+ LPY+CKK
Sbjct: 1163 WNDVPCNYNLPYICKK 1178
Score = 72.2 bits (174), Expect = 4e-11
Identities = 46/164 (28%), Positives = 73/164 (44%), Gaps = 10/164 (6%)
Query: 810 IPRGTDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAEL 869
+P + R D+ W +FQ Y++F +W A+R C LTS+HSQ E
Sbjct: 1041 LPSYSGSRCEKDTEGCDHNWHKFQGHCYRYFSRRRSWEDAERDCRRRAGHLTSIHSQEEH 1100
Query: 870 DFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRP--VGKDKKC 927
F+ + ++ WIGL+ + F+WTD + + + +W +P G +
Sbjct: 1101 GFI-------NSFGHENTWIGLNDRIVEQDFQWTDNTGLQYENWRENQPDNFFAGGEDCV 1153
Query: 928 VYMTASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGG 971
V ++ W D C LPYICK+ V PP++ L G
Sbjct: 1154 VLVSHEIGKWNDVPCNYNLPYICKKGTVLC-GPPPEVENAFLVG 1196
Score = 63.2 bits (151), Expect = 2e-08
Identities = 45/167 (26%), Positives = 71/167 (41%), Gaps = 27/167 (16%)
Query: 971 GCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNV 1030
GC +W +F C++ + R W +A+ C ++ L +I + E FI +
Sbjct: 1055 GCDHNWHKFQGHCYRYFSR----RRSWEDAERDCRRRAGHLTSIHSQEEHGFINSFGHEN 1110
Query: 1031 TFDLWIGLHAS--QRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAH 1088
T WIGL+ ++DFQW + L Y NW +P C V++ +H
Sbjct: 1111 T---WIGLNDRIVEQDFQWTDNTGLQYENWRENQPDNFFAGGE-----DCVVLV----SH 1158
Query: 1089 FTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNG 1135
G+W+D C +IC+KGT P P E ++L G
Sbjct: 1159 EIGKWNDVPCNYNL-PYICKKGT--------VLCGPPPEVENAFLVG 1196
Score = 57.4 bits (136), Expect = 1e-06
Identities = 62/227 (27%), Positives = 94/227 (41%), Gaps = 33/227 (14%)
Query: 666 TGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVAN 725
T C W +CY+ FS R SW A+ C+ L S+ S EE F+ +
Sbjct: 1053 TEGCDHNWHKFQG--HCYRYFSRRR-----SWEDAERDCRRRAGHLTSIHSQEEHGFINS 1105
Query: 726 MLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG- 784
FG HE W IGLN R Q ++W+D G Y N+ ++ D+ G
Sbjct: 1106 -----FG------HENTW--IGLNDRIVE--QDFQWTDNTGLQYENWRENQPDNFFAGGE 1150
Query: 785 -CAVLDLASL-QWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFFEH 842
C VL + +W + C+ L +ICK +GT + P P+ +L ++ E ++ H
Sbjct: 1151 DCVVLVSHEIGKWNDVPCNYNLPYICK--KGTVLCGP--PPEVENAFLVGKKKE-RYSIH 1205
Query: 843 HSTWAQAQRICTWFQAELTSVHSQAELD---FLSHNLQKFSRAQEQH 886
S Q + T HS + D L ++ RA+ H
Sbjct: 1206 SSVRYQCEEGFTQRHIPTIRCHSNGKWDRPKLLCTKPRRSHRARRHH 1252
Score = 55.0 bits (130), Expect = 6e-06
Identities = 60/251 (23%), Positives = 97/251 (37%), Gaps = 37/251 (14%)
Query: 456 SDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSI-------CKKAG 508
++GS+ + F N ++DC++ SPC I C
Sbjct: 993 ANGSICGCSCAPGFTGENCEIDIDDCLS----------SPCQNGGTCIDEVNAFVCLCLP 1042
Query: 509 QLSQGAAEED-HGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAF 567
S E+D GC W CY + ++ +A R C L +I ++ E F
Sbjct: 1043 SYSGSRCEKDTEGCDHNWHKFQGHCYRYFSRRRSWEDAERDCRRRAGHLTSIHSQEEHGF 1102
Query: 568 VSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQP-GYSRGG--CVALATG 624
++S + E W L D F W + Y +W +QP + GG CV L +
Sbjct: 1103 INSFGH----ENTWIGLNDRIVEQDFQWTDNTGLQYENWRENQPDNFFAGGEDCVVLVS- 1157
Query: 625 SAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDP---TPSLTGSCPQGWASDTKLRY 681
+G W C ++ YIC++ GT L GP P L G + ++ + +RY
Sbjct: 1158 HEIGKWNDVPC-NYNLPYICKK--GT----VLCGPPPEVENAFLVGKKKERYSIHSSVRY 1210
Query: 682 -CYKVFSSERL 691
C + F+ +
Sbjct: 1211 QCEEGFTQRHI 1221
Score = 48.8 bits (114), Expect = 4e-04
Identities = 38/143 (26%), Positives = 59/143 (40%), Gaps = 12/143 (8%)
Query: 1256 SYHGS-CPQGL--ADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENV 1312
SY GS C + D W F+ HCY + ++A + C+R G + SI + E+
Sbjct: 1043 SYSGSRCEKDTEGCDHNWHKFQGHCYRYFSRRR-SWEDAERDCRRRAGHLTSIHSQEEHG 1101
Query: 1313 FVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWI 1372
F+ S+ ++ W+G+N W DNT + Y NW C +
Sbjct: 1102 FI----NSFGHEN--TWIGLNDRIVEQDFQWTDNTGLQYENWRENQPDNFFAGGEDCVVL 1155
Query: 1373 QSNS-GLWRPGACTNITMGVVCK 1394
S+ G W C N + +CK
Sbjct: 1156 VSHEIGKWNDVPC-NYNLPYICK 1177
Score = 35.6 bits (80), Expect = 4.4
Identities = 35/164 (21%), Positives = 52/164 (31%), Gaps = 13/164 (7%)
Query: 1097 SCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLLQKPLRWHDALLLCESH 1156
+C +E + F+C S S + +R + W DA C
Sbjct: 1028 TCIDEVNAFVCLCLPSYSGSRCEKDTEGCDHNWHKFQGHCYRYFSRRRSWEDAERDCRRR 1087
Query: 1157 NASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQ 1216
L + F+ WIGL + + W L Y W++ +P
Sbjct: 1088 AGHLTSIHSQEEHGFINSFGH---ENTWIGLNDRIVEQDFQWTDNTGLQYENWRENQPDN 1144
Query: 1217 --PGG--CTYV--DVDGAWRTTSCDTKLQGAVC---GVSSGPPP 1251
GG C + G W C+ L +C V GPPP
Sbjct: 1145 FFAGGEDCVVLVSHEIGKWNDVPCNYNLP-YICKKGTVLCGPPP 1187
>ref|NP_031815.1| chondroitin sulfate proteoglycan 3 [Mus musculus]
sp|P55066|PGCN_MOUSE NEUROCAN CORE PROTEIN PRECURSOR
pir||S52781 neurocan - mouse
emb|CAA59216.1| (X84727) neurocan [Mus musculus]
Length = 1268
Score = 121 bits (301), Expect = 5e-26
Identities = 54/126 (42%), Positives = 78/126 (61%), Gaps = 4/126 (3%)
Query: 382 CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELW 441
C+ W FQGHCYR A +R+W+++++ C R G L S+HS E +FI E W
Sbjct: 1040 CDRGWHKFQGHCYRYFAHRRAWEDAERDCRRRAGHLTSVHSPEEHKFIN---SFGHENSW 1096
Query: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPE-GRWNDSPCNQSL 500
IGLND ++ +F+W+D + + + +W +P+NF EDCV + E GRWND PCN +L
Sbjct: 1097 IGLNDRTVERDFQWTDNTGLQYENWREKQPDNFFAGGEDCVVMVAHESGRWNDVPCNYNL 1156
Query: 501 PSICKK 506
P +CKK
Sbjct: 1157 PYVCKK 1162
Score = 92.1 bits (225), Expect = 4e-17
Identities = 52/151 (34%), Positives = 73/151 (47%), Gaps = 12/151 (7%)
Query: 213 CATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGAD 272
C YG C + C+ W K Q CY++ F +W +A C ++
Sbjct: 1022 CLCLPSYGGS----LCEKDTEGCDRGWHKFQ--GHCYRY-FAHRRAWEDAERDCRRRAGH 1074
Query: 273 LLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--P 330
L S+ E +IN G+ ++ WIGLND +QW+DN+ L+Y NW QPDN
Sbjct: 1075 LTSVHSPEEHKFINSF--GHENS-WIGLNDRTVERDFQWTDNTGLQYENWREKQPDNFFA 1131
Query: 331 SEENCGVIRTESSGGWQNRDCSIALPYVCKK 361
E+C V+ SG W + C+ LPYVCKK
Sbjct: 1132 GGEDCVVMVAHESGRWNDVPCNYNLPYVCKK 1162
Score = 74.9 bits (181), Expect = 6e-12
Identities = 48/149 (32%), Positives = 69/149 (46%), Gaps = 14/149 (9%)
Query: 827 REWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQH 886
R W +FQ Y++F H W A+R C LTSVHS E F+ + ++
Sbjct: 1042 RGWHKFQGHCYRYFAHRRAWEDAERDCRRRAGHLTSVHSPEEHKFI-------NSFGHEN 1094
Query: 887 WWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPV---GKDKKCVYMTASRED-WGDQRC 942
WIGL+ + F+WTD + + + +W +P G+D CV M A W D C
Sbjct: 1095 SWIGLNDRTVERDFQWTDNTGLQYENWREKQPDNFFAGGED--CVVMVAHESGRWNDVPC 1152
Query: 943 LTALPYICKRSNVTKETQPPDLPTTALGG 971
LPY+CK+ V PP + +L G
Sbjct: 1153 NYNLPYVCKKGTVLC-GPPPAVENASLVG 1180
Score = 66.3 bits (159), Expect = 2e-09
Identities = 41/143 (28%), Positives = 64/143 (44%), Gaps = 19/143 (13%)
Query: 971 GCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNV 1030
GC W +F C++ R W +A+ C ++ L ++ +P E FI +
Sbjct: 1039 GCDRGWHKFQGHCYRYFAH----RRAWEDAERDCRRRAGHLTSVHSPEEHKFINSFGHE- 1093
Query: 1031 TFDLWIGLH--ASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAH 1088
+ WIGL+ +RDFQW + L Y NW +P C V++ AH
Sbjct: 1094 --NSWIGLNDRTVERDFQWTDNTGLQYENWREKQPDNFFAGGE-----DCVVMV----AH 1142
Query: 1089 FTGRWDDRSCTEETHGFICQKGT 1111
+GRW+D C ++C+KGT
Sbjct: 1143 ESGRWNDVPCNYNL-PYVCKKGT 1164
Score = 53.9 bits (127), Expect = 1e-05
Identities = 43/148 (29%), Positives = 66/148 (44%), Gaps = 27/148 (18%)
Query: 666 TGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVAN 725
T C +GW +CY+ F+ R +W A+ C+ L S+ S EE F+ +
Sbjct: 1037 TEGCDRGWHKFQG--HCYRYFAHRR-----AWEDAERDCRRRAGHLTSVHSPEEHKFINS 1089
Query: 726 MLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG- 784
FG HE W IGLN R + ++W+D G Y N+ R + D+ G
Sbjct: 1090 -----FG------HENSW--IGLNDRTVE--RDFQWTDNTGLQYENW-REKQPDNFFAGG 1133
Query: 785 --CAVLDL-ASLQWVAMQCDTQLDWICK 809
C V+ S +W + C+ L ++CK
Sbjct: 1134 EDCVVMVAHESGRWNDVPCNYNLPYVCK 1161
Score = 53.5 bits (126), Expect = 2e-05
Identities = 50/201 (24%), Positives = 79/201 (38%), Gaps = 24/201 (11%)
Query: 516 EEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNW 575
++ GC +GW CY + + +A R C L ++ + E F++S +
Sbjct: 1035 KDTEGCDRGWHKFQGHCYRYFAHRRAWEDAERDCRRRAGHLTSVHSPEEHKFINSFGH-- 1092
Query: 576 EGEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQP-GYSRGG--CVALATGSAMGLWEV 632
E W L D F W + Y +W QP + GG CV + + G W
Sbjct: 1093 --ENSWIGLNDRTVERDFQWTDNTGLQYENWREKQPDNFFAGGEDCVVMVAHES-GRWND 1149
Query: 633 KNCTSFRARYICRQSLGTPVTPELPGPDP---TPSLTGSCPQGWASDTKLRY-CYKVFSS 688
C ++ Y+C++ GT L GP P SL G + +RY C + FS
Sbjct: 1150 VPC-NYNLPYVCKK--GT----VLCGPPPAVENASLVGVRKIKYNVHATVRYQCDEGFSQ 1202
Query: 689 ERL-----QDKKSWVQAQGAC 704
R+ ++ W + Q C
Sbjct: 1203 HRVATIRCRNNGKWDRPQIMC 1223
Score = 50.8 bits (119), Expect = 1e-04
Identities = 38/143 (26%), Positives = 58/143 (39%), Gaps = 12/143 (8%)
Query: 1256 SYHGS-CPQGL--ADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENV 1312
SY GS C + D W F+ HCY + ++A + C+R G + S+ E+
Sbjct: 1027 SYGGSLCEKDTEGCDRGWHKFQGHCYRYFAHRR-AWEDAERDCRRRAGHLTSVHSPEEHK 1085
Query: 1313 FVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YW 1371
F+ S+ ++ +W+G+N W DNT + Y NW C
Sbjct: 1086 FI----NSFGHEN--SWIGLNDRTVERDFQWTDNTGLQYENWREKQPDNFFAGGEDCVVM 1139
Query: 1372 IQSNSGLWRPGACTNITMGVVCK 1394
+ SG W C N + VCK
Sbjct: 1140 VAHESGRWNDVPC-NYNLPYVCK 1161
Score = 40.2 bits (92), Expect = 0.17
Identities = 43/170 (25%), Positives = 55/170 (32%), Gaps = 25/170 (14%)
Query: 1097 SCTEETHGFICQKGTDPSLSPSPAALPPAPGTE------LSYLNGTFRLLQKPLRWHDAL 1150
+C +E +GFIC PS TE + +R W DA
Sbjct: 1012 TCIDEVNGFICL------CLPSYGGSLCEKDTEGCDRGWHKFQGHCYRYFAHRRAWEDAE 1065
Query: 1151 LLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQ 1210
C L V P F+ WIGL R + W L Y W+
Sbjct: 1066 RDCRRRAGHLTSVHSPEEHKFINSFGH---ENSWIGLNDRTVERDFQWTDNTGLQYENWR 1122
Query: 1211 DGEPQQ--PGG--CTYV--DVDGAWRTTSCDTKLQGAVC---GVSSGPPP 1251
+ +P GG C + G W C+ L VC V GPPP
Sbjct: 1123 EKQPDNFFAGGEDCVVMVAHESGRWNDVPCNYNLP-YVCKKGTVLCGPPP 1171
>sp|P55067|PGCN_RAT NEUROCAN CORE PROTEIN PRECURSOR (245 KDA EARLY POSTNATAL CORE
GLYCOPROTEIN) [CONTAINS: 150 KDA ADULT CORE GLYCOPROTEIN]
pir||S28764 neurocan precursor - rat
gb|AAC37679.1| (M97161) neurocan [Rattus norvegicus]
Length = 1257
Score = 121 bits (301), Expect = 5e-26
Identities = 54/126 (42%), Positives = 78/126 (61%), Gaps = 4/126 (3%)
Query: 382 CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELW 441
C+ W FQGHCYR A +R+W+++++ C R G L S+HS E +FI E W
Sbjct: 1029 CDRGWHKFQGHCYRYFAHRRAWEDAERDCRRRAGHLTSVHSPEEHKFIN---SFGHENSW 1085
Query: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPE-GRWNDSPCNQSL 500
IGLND ++ +F+W+D + + + +W +P+NF EDCV + E GRWND PCN +L
Sbjct: 1086 IGLNDRTVERDFQWTDNTGLQYENWREKQPDNFFAGGEDCVVMVAHENGRWNDVPCNYNL 1145
Query: 501 PSICKK 506
P +CKK
Sbjct: 1146 PYVCKK 1151
Score = 91.3 bits (223), Expect = 7e-17
Identities = 51/151 (33%), Positives = 74/151 (48%), Gaps = 12/151 (7%)
Query: 213 CATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGAD 272
C YG + C + C+ W K Q CY++ F +W +A C ++
Sbjct: 1011 CLCLPSYGGN----LCEKDTEGCDRGWHKFQ--GHCYRY-FAHRRAWEDAERDCRRRAGH 1063
Query: 273 LLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--P 330
L S+ E +IN G+ ++ WIGLND +QW+DN+ L+Y NW QPDN
Sbjct: 1064 LTSVHSPEEHKFINSF--GHENS-WIGLNDRTVERDFQWTDNTGLQYENWREKQPDNFFA 1120
Query: 331 SEENCGVIRTESSGGWQNRDCSIALPYVCKK 361
E+C V+ +G W + C+ LPYVCKK
Sbjct: 1121 GGEDCVVMVAHENGRWNDVPCNYNLPYVCKK 1151
Score = 74.9 bits (181), Expect = 6e-12
Identities = 48/149 (32%), Positives = 69/149 (46%), Gaps = 14/149 (9%)
Query: 827 REWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQH 886
R W +FQ Y++F H W A+R C LTSVHS E F+ + ++
Sbjct: 1031 RGWHKFQGHCYRYFAHRRAWEDAERDCRRRAGHLTSVHSPEEHKFI-------NSFGHEN 1083
Query: 887 WWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPV---GKDKKCVYMTASRED-WGDQRC 942
WIGL+ + F+WTD + + + +W +P G+D CV M A W D C
Sbjct: 1084 SWIGLNDRTVERDFQWTDNTGLQYENWREKQPDNFFAGGED--CVVMVAHENGRWNDVPC 1141
Query: 943 LTALPYICKRSNVTKETQPPDLPTTALGG 971
LPY+CK+ V PP + +L G
Sbjct: 1142 NYNLPYVCKKGTVLC-GPPPAVENASLVG 1169
Score = 66.0 bits (158), Expect = 3e-09
Identities = 41/143 (28%), Positives = 63/143 (43%), Gaps = 19/143 (13%)
Query: 971 GCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNV 1030
GC W +F C++ R W +A+ C ++ L ++ +P E FI +
Sbjct: 1028 GCDRGWHKFQGHCYRYFAH----RRAWEDAERDCRRRAGHLTSVHSPEEHKFINSFGHE- 1082
Query: 1031 TFDLWIGLH--ASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAH 1088
+ WIGL+ +RDFQW + L Y NW +P C V++ AH
Sbjct: 1083 --NSWIGLNDRTVERDFQWTDNTGLQYENWREKQPDNFFAGGE-----DCVVMV----AH 1131
Query: 1089 FTGRWDDRSCTEETHGFICQKGT 1111
GRW+D C ++C+KGT
Sbjct: 1132 ENGRWNDVPCNYNL-PYVCKKGT 1153
Score = 53.1 bits (125), Expect = 2e-05
Identities = 54/214 (25%), Positives = 88/214 (40%), Gaps = 51/214 (23%)
Query: 666 TGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVAN 725
T C +GW +CY+ F+ R +W A+ C+ L S+ S EE F+ +
Sbjct: 1026 TEGCDRGWHKFQG--HCYRYFAHRR-----AWEDAERDCRRRAGHLTSVHSPEEHKFINS 1078
Query: 726 MLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG- 784
FG HE W IGLN R + ++W+D G Y N+ R + D+ G
Sbjct: 1079 -----FG------HENSW--IGLNDRTVE--RDFQWTDNTGLQYENW-REKQPDNFFAGG 1122
Query: 785 --CAVLDL-ASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGR------------REW 829
C V+ + +W + C+ L ++CK +GT + P + +
Sbjct: 1123 EDCVVMVAHENGRWNDVPCNYNLPYVCK--KGTVLCGPPPAVENASLVGVRKVKYNVHAT 1180
Query: 830 LRFQEAEYKFFEHH---------STWAQAQRICT 854
+R+Q + F +HH W + Q +CT
Sbjct: 1181 VRYQ-CDEGFSQHHVATIRCRSNGKWDRPQIVCT 1213
Score = 51.9 bits (122), Expect = 5e-05
Identities = 50/201 (24%), Positives = 76/201 (36%), Gaps = 24/201 (11%)
Query: 516 EEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNW 575
++ GC +GW CY + + +A R C L ++ + E F++S +
Sbjct: 1024 KDTEGCDRGWHKFQGHCYRYFAHRRAWEDAERDCRRRAGHLTSVHSPEEHKFINSFGH-- 1081
Query: 576 EGEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQP-GYSRGG--CVALATGSAMGLWEV 632
E W L D F W + Y +W QP + GG CV + G W
Sbjct: 1082 --ENSWIGLNDRTVERDFQWTDNTGLQYENWREKQPDNFFAGGEDCVVM-VAHENGRWND 1138
Query: 633 KNCTSFRARYICRQSLGTPVTPELPGPDP---TPSLTGSCPQGWASDTKLRY-CYKVFSS 688
C ++ Y+C++ GT L GP P SL G + +RY C + FS
Sbjct: 1139 VPC-NYNLPYVCKK--GT----VLCGPPPAVENASLVGVRKVKYNVHATVRYQCDEGFSQ 1191
Query: 689 E-----RLQDKKSWVQAQGAC 704
R + W + Q C
Sbjct: 1192 HHVATIRCRSNGKWDRPQIVC 1212
Score = 49.2 bits (115), Expect = 3e-04
Identities = 32/129 (24%), Positives = 52/129 (39%), Gaps = 9/129 (6%)
Query: 1267 DSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSR 1326
D W F+ HCY + ++A + C+R G + S+ E+ F+ S+ ++
Sbjct: 1030 DRGWHKFQGHCYRYFAHRR-AWEDAERDCRRRAGHLTSVHSPEEHKFI----NSFGHEN- 1083
Query: 1327 GAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YWIQSNSGLWRPGACT 1385
+W+G+N W DNT + Y NW C + +G W C
Sbjct: 1084 -SWIGLNDRTVERDFQWTDNTGLQYENWREKQPDNFFAGGEDCVVMVAHENGRWNDVPC- 1141
Query: 1386 NITMGVVCK 1394
N + VCK
Sbjct: 1142 NYNLPYVCK 1150
Score = 40.2 bits (92), Expect = 0.17
Identities = 43/170 (25%), Positives = 56/170 (32%), Gaps = 25/170 (14%)
Query: 1097 SCTEETHGFICQKGTDPSLSPSPAALPPAPGTE------LSYLNGTFRLLQKPLRWHDAL 1150
+C +E +GFIC PS TE + +R W DA
Sbjct: 1001 TCIDEVNGFICL------CLPSYGGNLCEKDTEGCDRGWHKFQGHCYRYFAHRRAWEDAE 1054
Query: 1151 LLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQ 1210
C L V P F+ WIGL R + W L Y W+
Sbjct: 1055 RDCRRRAGHLTSVHSPEEHKFINSFGH---ENSWIGLNDRTVERDFQWTDNTGLQYENWR 1111
Query: 1211 DGEPQQ--PGG--CTYV--DVDGAWRTTSCDTKLQGAVC---GVSSGPPP 1251
+ +P GG C + +G W C+ L VC V GPPP
Sbjct: 1112 EKQPDNFFAGGEDCVVMVAHENGRWNDVPCNYNLP-YVCKKGTVLCGPPP 1160
>sp|P07897|PGCA_RAT AGGRECAN CORE PROTEIN PRECURSOR (CARTILAGE-SPECIFIC PROTEOGLYCAN CORE
PROTEIN) (CSPCP)
pir||A28452 proteoglycan core protein precursor, cartilage - rat
Length = 2124
Score = 120 bits (298), Expect = 1e-25
Identities = 72/227 (31%), Positives = 109/227 (47%), Gaps = 17/227 (7%)
Query: 281 EQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRT 340
++T I+G + ++S + + ++ W S P + L E P NPS
Sbjct: 1826 DRTEISGEWSDHTSEVNVTVSTTVPESRWAQSTQHPTETLQ-EIGSP-NPSYSGEETQTA 1883
Query: 341 ESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEK 400
E++ + P + + + E T D+ +CE W FQGHCYR ++
Sbjct: 1884 ETAKSLTDT------PTLASPEGSGETESTAADQ-----EQCEEGWTKFQGHCYRHFPDR 1932
Query: 401 RSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSL 460
+W ++++ C L SI + E EF+ K + + WIGLND ++ +F WSDG
Sbjct: 1933 ETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQ---DYQWIGLNDRTIEGDFRWSDGHS 1989
Query: 461 VSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSLPSICKK 506
+ F W P +P+NF + EDCV IW G WND PCN LP CKK
Sbjct: 1990 LQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPCNYQLPFTCKK 2036
Score = 87.0 bits (212), Expect = 1e-15
Identities = 49/137 (35%), Positives = 68/137 (48%), Gaps = 8/137 (5%)
Query: 235 CETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSS 294
CE W K Q CY+ +F +W +A C +Q + L SI EQ ++N Y
Sbjct: 1914 CEEGWTKFQ--GHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQ- 1969
Query: 295 TLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTESSGGWQNRDCS 352
WIGLND G ++WSD L++ W +QPDN + E+C V+ G W + C+
Sbjct: 1970 --WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPCN 2027
Query: 353 IALPYVCKKKPNATAEP 369
LP+ CKK A EP
Sbjct: 2028 YQLPFTCKKGTVACGEP 2044
Score = 85.0 bits (207), Expect = 6e-15
Identities = 59/198 (29%), Positives = 87/198 (43%), Gaps = 24/198 (12%)
Query: 821 DSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFS 880
D Q W +FQ Y+ F TW A+R C Q+ L+S+ + E +F++ N Q +
Sbjct: 1910 DQEQCEEGWTKFQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQ 1969
Query: 881 RAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR---PVGKDKKCVYMT-ASRED 936
WIGL+ +G FRW+DG + F W P +P G+D CV M R +
Sbjct: 1970 -------WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGED--CVVMIWHERGE 2020
Query: 937 WGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLN----KCFQ--VQGQE 990
W D C LP+ CK+ V +PP + G D + + +C + VQ
Sbjct: 2021 WNDVPCNYQLPFTCKKGTVAC-GEPPAVEHARTLGQKKDRYEISSLVRYQCTEGFVQRHV 2079
Query: 991 P----QSRVKWSEAQFSC 1004
P Q W E + +C
Sbjct: 2080 PTIRCQPSADWEEPRITC 2097
Score = 64.4 bits (154), Expect = 9e-09
Identities = 58/238 (24%), Positives = 93/238 (38%), Gaps = 34/238 (14%)
Query: 477 SLEDCVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLG 536
SL D T+ PEG +G+ AA+++ C +GWT CY
Sbjct: 1888 SLTDTPTLASPEG-----------------SGETESTAADQEQ-CEEGWTKFQGHCYRHF 1929
Query: 537 EDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWL 596
D+ T+ +A R C + S L +I EQ FV+ +Y W L D G F W
Sbjct: 1930 PDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQ----DYQWIGLNDRTIEGDFRWS 1985
Query: 597 SGDEVMYTHWNRDQPG--YSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTP 654
G + + W +QP ++ G + G W C +++ + C++ GT
Sbjct: 1986 DGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPC-NYQLPFTCKK--GTVACG 2042
Query: 655 ELPGPDPTPSLTGSCPQGWASDTKLRY-CYKVFSSE-----RLQDKKSWVQAQGACQE 706
E P + +L G + + +RY C + F R Q W + + C +
Sbjct: 2043 EPPAVEHARTL-GQKKDRYEISSLVRYQCTEGFVQRHVPTIRCQPSADWEEPRITCTD 2099
Score = 61.7 bits (147), Expect = 6e-08
Identities = 38/142 (26%), Positives = 61/142 (42%), Gaps = 19/142 (13%)
Query: 972 CPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT 1031
C W +F C++ R W +A+ C +Q++ L +I P EQ F+ + +
Sbjct: 1914 CEEGWTKFQGHCYR----HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQ 1969
Query: 1032 FDLWIGLH--ASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHF 1089
WIGL+ + DF+W + L + W P +P C V++ H
Sbjct: 1970 ---WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGE-----DCVVMIW----HE 2017
Query: 1090 TGRWDDRSCTEETHGFICQKGT 1111
G W+D C + F C+KGT
Sbjct: 2018 RGEWNDVPCNYQL-PFTCKKGT 2038
Score = 60.9 bits (145), Expect = 1e-07
Identities = 50/167 (29%), Positives = 78/167 (45%), Gaps = 33/167 (19%)
Query: 653 TPELPGPD------PTPSLTGSCPQGWASDTKLR-YCYKVFSSERLQDKKSWVQAQGACQ 705
TP L P+ T + C +GW TK + +CY+ F D+++WV A+ C+
Sbjct: 1892 TPTLASPEGSGETESTAADQEQCEEGW---TKFQGHCYRHFP-----DRETWVDAERRCR 1943
Query: 706 ELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGV 765
E + L S+ + EE+ FV NK + Q + WIGLN R G +RWSDG
Sbjct: 1944 EQQSHLSSIVTPEEQEFV----NK---------NAQDYQWIGLNDRTIEG--DFRWSDGH 1988
Query: 766 GFSYHNFDRSRHDDDDIRG--CAVLDLASL-QWVAMQCDTQLDWICK 809
+ + ++ D+ G C V+ +W + C+ QL + CK
Sbjct: 1989 SLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPCNYQLPFTCK 2035
Score = 46.5 bits (108), Expect = 0.002
Identities = 33/133 (24%), Positives = 50/133 (36%), Gaps = 9/133 (6%)
Query: 1263 QGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYE 1322
Q + W F+ HCY H +A +RC+ + SI+ E FV ++ Q Y+
Sbjct: 1911 QEQCEEGWTKFQGHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQ 1969
Query: 1323 GQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YWIQSNSGLWRP 1381
W+G+N G W D ++ + W P + C I G W
Sbjct: 1970 ------WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWND 2023
Query: 1382 GACTNITMGVVCK 1394
C N + CK
Sbjct: 2024 VPC-NYQLPFTCK 2035
>pir||T42630 aggrecan - bovine
gb|AAB38524.1| (U76615) aggrecan [Bos taurus]
Length = 2327
Score = 119 bits (296), Expect = 2e-25
Identities = 76/244 (31%), Positives = 112/244 (45%), Gaps = 19/244 (7%)
Query: 265 SCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKY-LNWE 323
S E G+ + ++T +G L+G++S L I ++ W P + L E
Sbjct: 2013 SVEASGSPSATPLASGDRTDTSGDLSGHTSGLDIVISTTIPESEWTQQTQRPAEARLEIE 2072
Query: 324 SDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECE 383
S P + EE+ S D SI P + + + CE
Sbjct: 2073 SSSPVHSGEESQTADTATSP-----TDASI---------PASAGGTDDSEATTTDQKLCE 2118
Query: 384 PSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIG 443
W FQGHCYR ++ +W +++ C + L SI + E EF+ + + WIG
Sbjct: 2119 EGWTKFQGHCYRHFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQ---DYQWIG 2175
Query: 444 LNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSLPS 502
LND ++ +F WSDG + F +W P +P+NF + EDCV IW +G WND PCN LP
Sbjct: 2176 LNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGEDCVVMIWHEKGEWNDVPCNYQLPF 2235
Query: 503 ICKK 506
CKK
Sbjct: 2236 TCKK 2239
Score = 95.2 bits (233), Expect = 5e-18
Identities = 61/192 (31%), Positives = 90/192 (46%), Gaps = 24/192 (12%)
Query: 235 CETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSS 294
CE W K Q CY+ +F +W +A + C +Q + L SI EQ ++N Y
Sbjct: 2117 CEEGWTKFQ--GHCYR-HFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQDYQ- 2172
Query: 295 TLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTESSGGWQNRDCS 352
WIGLND G ++WSD L++ NW +QPDN + E+C V+ G W + C+
Sbjct: 2173 --WIGLNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGEDCVVMIWHEKGEWNDVPCN 2230
Query: 353 IALPYVCKKKPNATAEP----------TPPDRW---ANVKVECEPSWQPFQGHCYRLQAE 399
LP+ CKK A EP DR+ A V+ +C + QGH ++ +
Sbjct: 2231 YQLPFTCKKGTVACGEPPVVEHARIFGQKKDRYEINALVRYQCTEGF--IQGHVPTIRCQ 2288
Query: 400 KRS-WQESKKAC 410
W+E + C
Sbjct: 2289 PSGHWEEPRITC 2300
Score = 86.2 bits (210), Expect = 2e-15
Identities = 61/208 (29%), Positives = 96/208 (45%), Gaps = 26/208 (12%)
Query: 813 GTDVREPDDSPQGRRE--WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELD 870
GTD E + Q E W +FQ Y+ F +TW A+ C Q+ L+S+ + E +
Sbjct: 2103 GTDDSEATTTDQKLCEEGWTKFQGHCYRHFPDRATWVDAESQCRKQQSHLSSIVTPEEQE 2162
Query: 871 FLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR---PVGKDKKC 927
F+++N Q + WIGL+ +G FRW+DG + F +W P +P G+D C
Sbjct: 2163 FVNNNAQDYQ-------WIGLNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGED--C 2213
Query: 928 VYMT-ASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQF----LNK 982
V M + +W D C LP+ CK+ V +PP + + G D + +
Sbjct: 2214 VVMIWHEKGEWNDVPCNYQLPFTCKKGTVAC-GEPPVVEHARIFGQKKDRYEINALVRYQ 2272
Query: 983 CFQ--VQGQEPQSRVK----WSEAQFSC 1004
C + +QG P R + W E + +C
Sbjct: 2273 CTEGFIQGHVPTIRCQPSGHWEEPRITC 2300
Score = 66.0 bits (158), Expect = 3e-09
Identities = 42/155 (27%), Positives = 66/155 (42%), Gaps = 19/155 (12%)
Query: 959 TQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPL 1018
T + TT C W +F C++ R W +A+ C +Q++ L +I P
Sbjct: 2104 TDDSEATTTDQKLCEEGWTKFQGHCYR----HFPDRATWVDAESQCRKQQSHLSSIVTPE 2159
Query: 1019 EQAFITASLPNVTFDLWIGLHAS--QRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPT 1076
EQ F+ + + WIGL+ + DF+W + L + NW P +P
Sbjct: 2160 EQEFVNNNAQDYQ---WIGLNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGE----- 2211
Query: 1077 SCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGT 1111
C V++ H G W+D C + F C+KGT
Sbjct: 2212 DCVVMIW----HEKGEWNDVPCNYQL-PFTCKKGT 2241
Score = 60.9 bits (145), Expect = 1e-07
Identities = 43/145 (29%), Positives = 70/145 (47%), Gaps = 27/145 (18%)
Query: 669 CPQGWASDTKLR-YCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANML 727
C +GW TK + +CY+ F D+ +WV A+ C++ + L S+ + EE+ FV N
Sbjct: 2117 CEEGW---TKFQGHCYRHFP-----DRATWVDAESQCRKQQSHLSSIVTPEEQEFVNN-- 2166
Query: 728 NKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--C 785
+ Q + WIGLN + G +RWSDG + N+ ++ D+ G C
Sbjct: 2167 -----------NAQDYQWIGLNDKTIEG--DFRWSDGHSLQFENWRPNQPDNFFATGEDC 2213
Query: 786 AVLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ QL + CK
Sbjct: 2214 VVMIWHEKGEWNDVPCNYQLPFTCK 2238
Score = 60.5 bits (144), Expect = 1e-07
Identities = 46/176 (26%), Positives = 72/176 (40%), Gaps = 11/176 (6%)
Query: 486 GPEGRWNDSPCNQSLPSICKKAGQL--SQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYS 543
G E + D+ + + SI AG S+ + C +GWT CY D+ T+
Sbjct: 2080 GEESQTADTATSPTDASIPASAGGTDDSEATTTDQKLCEEGWTKFQGHCYRHFPDRATWV 2139
Query: 544 EARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDEVMY 603
+A C S L +I EQ FV+ N +Y W L D G F W G + +
Sbjct: 2140 DAESQCRKQQSHLSSIVTPEEQEFVN----NNAQDYQWIGLNDKTIEGDFRWSDGHSLQF 2195
Query: 604 THWNRDQPG--YSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELP 657
+W +QP ++ G + G W C +++ + C++ GT E P
Sbjct: 2196 ENWRPNQPDNFFATGEDCVVMIWHEKGEWNDVPC-NYQLPFTCKK--GTVACGEPP 2248
Score = 50.8 bits (119), Expect = 1e-04
Identities = 34/133 (25%), Positives = 51/133 (37%), Gaps = 9/133 (6%)
Query: 1263 QGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYE 1322
Q L + W F+ HCY H +A +C++ + SI+ E FV + Q Y+
Sbjct: 2114 QKLCEEGWTKFQGHCYR-HFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQDYQ 2172
Query: 1323 GQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YWIQSNSGLWRP 1381
W+G+N G W D ++ + NW P + C I G W
Sbjct: 2173 ------WIGLNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGEDCVVMIWHEKGEWND 2226
Query: 1382 GACTNITMGVVCK 1394
C N + CK
Sbjct: 2227 VPC-NYQLPFTCK 2238
Score = 34.8 bits (78), Expect = 7.5
Identities = 39/166 (23%), Positives = 60/166 (35%), Gaps = 30/166 (18%)
Query: 1112 DPSLSPSPAALPP-APGTELSYLNGT----------------FRLLQKPLRWHDALLLCE 1154
D + SP+ A++P A GT+ S T +R W DA C
Sbjct: 2087 DTATSPTDASIPASAGGTDDSEATTTDQKLCEEGWTKFQGHCYRHFPDRATWVDAESQCR 2146
Query: 1155 SHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEP 1214
+ L+ + P Q F+ A+ + WIGL + + W L + W+ +P
Sbjct: 2147 KQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDKTIEGDFRWSDGHSLQFENWRPNQP 2203
Query: 1215 QQ---PGGCTYVDV---DGAWRTTSCDTKLQGAVC---GVSSGPPP 1251
G V + G W C+ +L C V+ G PP
Sbjct: 2204 DNFFATGEDCVVMIWHEKGEWNDVPCNYQLP-FTCKKGTVACGEPP 2248
>pir||A39808 proteoglycan core protein, cartilage - bovine (fragments)
Length = 1340
Score = 119 bits (296), Expect = 2e-25
Identities = 76/244 (31%), Positives = 112/244 (45%), Gaps = 19/244 (7%)
Query: 265 SCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKY-LNWE 323
S E G+ + ++T +G L+G++S L I ++ W P + L E
Sbjct: 1026 SVEASGSPSATPLASGDRTDTSGDLSGHTSGLDIVISTTIPESEWTQQTQRPAEARLEIE 1085
Query: 324 SDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECE 383
S P + EE+ S D SI P + + + CE
Sbjct: 1086 SSSPVHSGEESQTADTATSP-----TDASI---------PASAGGTDDSEATTTDQKLCE 1131
Query: 384 PSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIG 443
W FQGHCYR ++ +W +++ C + L SI + E EF+ + + WIG
Sbjct: 1132 EGWTKFQGHCYRHFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQ---DYQWIG 1188
Query: 444 LNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSLPS 502
LND ++ +F WSDG + F +W P +P+NF + EDCV IW +G WND PCN LP
Sbjct: 1189 LNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGEDCVVMIWHEKGEWNDVPCNYQLPF 1248
Query: 503 ICKK 506
CKK
Sbjct: 1249 TCKK 1252
Score = 95.2 bits (233), Expect = 5e-18
Identities = 61/192 (31%), Positives = 90/192 (46%), Gaps = 24/192 (12%)
Query: 235 CETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSS 294
CE W K Q CY+ +F +W +A + C +Q + L SI EQ ++N Y
Sbjct: 1130 CEEGWTKFQ--GHCYR-HFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQDYQ- 1185
Query: 295 TLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTESSGGWQNRDCS 352
WIGLND G ++WSD L++ NW +QPDN + E+C V+ G W + C+
Sbjct: 1186 --WIGLNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGEDCVVMIWHEKGEWNDVPCN 1243
Query: 353 IALPYVCKKKPNATAEP----------TPPDRW---ANVKVECEPSWQPFQGHCYRLQAE 399
LP+ CKK A EP DR+ A V+ +C + QGH ++ +
Sbjct: 1244 YQLPFTCKKGTVACGEPPVVEHARIFGQKKDRYEINALVRYQCTEGF--IQGHVPTIRCQ 1301
Query: 400 KRS-WQESKKAC 410
W+E + C
Sbjct: 1302 PSGHWEEPRITC 1313
Score = 86.2 bits (210), Expect = 2e-15
Identities = 61/208 (29%), Positives = 96/208 (45%), Gaps = 26/208 (12%)
Query: 813 GTDVREPDDSPQGRRE--WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELD 870
GTD E + Q E W +FQ Y+ F +TW A+ C Q+ L+S+ + E +
Sbjct: 1116 GTDDSEATTTDQKLCEEGWTKFQGHCYRHFPDRATWVDAESQCRKQQSHLSSIVTPEEQE 1175
Query: 871 FLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR---PVGKDKKC 927
F+++N Q + WIGL+ +G FRW+DG + F +W P +P G+D C
Sbjct: 1176 FVNNNAQDYQ-------WIGLNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGED--C 1226
Query: 928 VYMT-ASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQF----LNK 982
V M + +W D C LP+ CK+ V +PP + + G D + +
Sbjct: 1227 VVMIWHEKGEWNDVPCNYQLPFTCKKGTVAC-GEPPVVEHARIFGQKKDRYEINALVRYQ 1285
Query: 983 CFQ--VQGQEPQSRVK----WSEAQFSC 1004
C + +QG P R + W E + +C
Sbjct: 1286 CTEGFIQGHVPTIRCQPSGHWEEPRITC 1313
Score = 66.0 bits (158), Expect = 3e-09
Identities = 42/155 (27%), Positives = 66/155 (42%), Gaps = 19/155 (12%)
Query: 959 TQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPL 1018
T + TT C W +F C++ R W +A+ C +Q++ L +I P
Sbjct: 1117 TDDSEATTTDQKLCEEGWTKFQGHCYR----HFPDRATWVDAESQCRKQQSHLSSIVTPE 1172
Query: 1019 EQAFITASLPNVTFDLWIGLHAS--QRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPT 1076
EQ F+ + + WIGL+ + DF+W + L + NW P +P
Sbjct: 1173 EQEFVNNNAQDYQ---WIGLNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGE----- 1224
Query: 1077 SCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGT 1111
C V++ H G W+D C + F C+KGT
Sbjct: 1225 DCVVMIW----HEKGEWNDVPCNYQL-PFTCKKGT 1254
Score = 60.9 bits (145), Expect = 1e-07
Identities = 43/145 (29%), Positives = 70/145 (47%), Gaps = 27/145 (18%)
Query: 669 CPQGWASDTKLR-YCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANML 727
C +GW TK + +CY+ F D+ +WV A+ C++ + L S+ + EE+ FV N
Sbjct: 1130 CEEGW---TKFQGHCYRHFP-----DRATWVDAESQCRKQQSHLSSIVTPEEQEFVNN-- 1179
Query: 728 NKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--C 785
+ Q + WIGLN + G +RWSDG + N+ ++ D+ G C
Sbjct: 1180 -----------NAQDYQWIGLNDKTIEG--DFRWSDGHSLQFENWRPNQPDNFFATGEDC 1226
Query: 786 AVLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ QL + CK
Sbjct: 1227 VVMIWHEKGEWNDVPCNYQLPFTCK 1251
Score = 60.5 bits (144), Expect = 1e-07
Identities = 46/176 (26%), Positives = 72/176 (40%), Gaps = 11/176 (6%)
Query: 486 GPEGRWNDSPCNQSLPSICKKAGQL--SQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYS 543
G E + D+ + + SI AG S+ + C +GWT CY D+ T+
Sbjct: 1093 GEESQTADTATSPTDASIPASAGGTDDSEATTTDQKLCEEGWTKFQGHCYRHFPDRATWV 1152
Query: 544 EARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDEVMY 603
+A C S L +I EQ FV+ N +Y W L D G F W G + +
Sbjct: 1153 DAESQCRKQQSHLSSIVTPEEQEFVN----NNAQDYQWIGLNDKTIEGDFRWSDGHSLQF 1208
Query: 604 THWNRDQPG--YSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELP 657
+W +QP ++ G + G W C +++ + C++ GT E P
Sbjct: 1209 ENWRPNQPDNFFATGEDCVVMIWHEKGEWNDVPC-NYQLPFTCKK--GTVACGEPP 1261
Score = 50.8 bits (119), Expect = 1e-04
Identities = 34/133 (25%), Positives = 51/133 (37%), Gaps = 9/133 (6%)
Query: 1263 QGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYE 1322
Q L + W F+ HCY H +A +C++ + SI+ E FV + Q Y+
Sbjct: 1127 QKLCEEGWTKFQGHCYR-HFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQDYQ 1185
Query: 1323 GQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YWIQSNSGLWRP 1381
W+G+N G W D ++ + NW P + C I G W
Sbjct: 1186 ------WIGLNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGEDCVVMIWHEKGEWND 1239
Query: 1382 GACTNITMGVVCK 1394
C N + CK
Sbjct: 1240 VPC-NYQLPFTCK 1251
Score = 34.8 bits (78), Expect = 7.5
Identities = 39/166 (23%), Positives = 60/166 (35%), Gaps = 30/166 (18%)
Query: 1112 DPSLSPSPAALPP-APGTELSYLNGT----------------FRLLQKPLRWHDALLLCE 1154
D + SP+ A++P A GT+ S T +R W DA C
Sbjct: 1100 DTATSPTDASIPASAGGTDDSEATTTDQKLCEEGWTKFQGHCYRHFPDRATWVDAESQCR 1159
Query: 1155 SHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEP 1214
+ L+ + P Q F+ A+ + WIGL + + W L + W+ +P
Sbjct: 1160 KQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDKTIEGDFRWSDGHSLQFENWRPNQP 1216
Query: 1215 QQ---PGGCTYVDV---DGAWRTTSCDTKLQGAVC---GVSSGPPP 1251
G V + G W C+ +L C V+ G PP
Sbjct: 1217 DNFFATGEDCVVMIWHEKGEWNDVPCNYQLP-FTCKKGTVACGEPP 1261
>gb|AAA21000.1| (J03485) aggrecan [Rattus norvegicus]
Length = 2162
Score = 118 bits (294), Expect = 4e-25
Identities = 54/127 (42%), Positives = 73/127 (56%), Gaps = 4/127 (3%)
Query: 381 ECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEEL 440
+CE W FQGHCYR ++ +W ++++ C L SI + E EF+ K + +
Sbjct: 1951 QCEEGWTKFQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQ---DYQ 2007
Query: 441 WIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQS 499
WIGLND ++ +F WSDG + F W P +P+NF + EDCV IW G WND PCN
Sbjct: 2008 WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPCNYQ 2067
Query: 500 LPSICKK 506
LP CKK
Sbjct: 2068 LPFTCKK 2074
Score = 92.1 bits (225), Expect = 4e-17
Identities = 52/148 (35%), Positives = 71/148 (47%), Gaps = 8/148 (5%)
Query: 224 RWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQT 283
R C I CE W K Q CY+ +F +W +A C +Q + L SI EQ
Sbjct: 1941 RGDLCEIDQEQCEEGWTKFQ--GHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEEQE 1997
Query: 284 YINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTE 341
++N Y WIGLND G ++WSD L++ W +QPDN + E+C V+
Sbjct: 1998 FVNKNAQDYQ---WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVMIWH 2054
Query: 342 SSGGWQNRDCSIALPYVCKKKPNATAEP 369
G W + C+ LP+ CKK A EP
Sbjct: 2055 ERGEWNDVPCNYQLPFTCKKGTVACGEP 2082
Score = 85.0 bits (207), Expect = 6e-15
Identities = 59/198 (29%), Positives = 87/198 (43%), Gaps = 24/198 (12%)
Query: 821 DSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFS 880
D Q W +FQ Y+ F TW A+R C Q+ L+S+ + E +F++ N Q +
Sbjct: 1948 DQEQCEEGWTKFQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQ 2007
Query: 881 RAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR---PVGKDKKCVYMT-ASRED 936
WIGL+ +G FRW+DG + F W P +P G+D CV M R +
Sbjct: 2008 -------WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGED--CVVMIWHERGE 2058
Query: 937 WGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLN----KCFQ--VQGQE 990
W D C LP+ CK+ V +PP + G D + + +C + VQ
Sbjct: 2059 WNDVPCNYQLPFTCKKGTVAC-GEPPAVEHARTLGQKKDRYEISSLVRYQCTEGFVQRHV 2117
Query: 991 P----QSRVKWSEAQFSC 1004
P Q W E + +C
Sbjct: 2118 PTIRCQPSADWEEPRITC 2135
Score = 61.7 bits (147), Expect = 6e-08
Identities = 38/142 (26%), Positives = 61/142 (42%), Gaps = 19/142 (13%)
Query: 972 CPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT 1031
C W +F C++ R W +A+ C +Q++ L +I P EQ F+ + +
Sbjct: 1952 CEEGWTKFQGHCYR----HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQ 2007
Query: 1032 FDLWIGLH--ASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHF 1089
WIGL+ + DF+W + L + W P +P C V++ H
Sbjct: 2008 ---WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGE-----DCVVMIW----HE 2055
Query: 1090 TGRWDDRSCTEETHGFICQKGT 1111
G W+D C + F C+KGT
Sbjct: 2056 RGEWNDVPCNYQL-PFTCKKGT 2076
Score = 59.7 bits (142), Expect = 2e-07
Identities = 45/145 (31%), Positives = 71/145 (48%), Gaps = 27/145 (18%)
Query: 669 CPQGWASDTKLR-YCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANML 727
C +GW TK + +CY+ F D+++WV A+ C+E + L S+ + EE+ FV
Sbjct: 1952 CEEGW---TKFQGHCYRHFP-----DRETWVDAERRCREQQSHLSSIVTPEEQEFV---- 1999
Query: 728 NKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--C 785
NK + Q + WIGLN R G +RWSDG + + ++ D+ G C
Sbjct: 2000 NK---------NAQDYQWIGLNDRTIEG--DFRWSDGHSLQFEKWRPNQPDNFFATGEDC 2048
Query: 786 AVLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ QL + CK
Sbjct: 2049 VVMIWHERGEWNDVPCNYQLPFTCK 2073
Score = 59.7 bits (142), Expect = 2e-07
Identities = 48/194 (24%), Positives = 77/194 (38%), Gaps = 16/194 (8%)
Query: 521 CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYF 580
C +GWT CY D+ T+ +A R C + S L +I EQ FV+ +Y
Sbjct: 1952 CEEGWTKFQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQ----DYQ 2007
Query: 581 WTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG--YSRGGCVALATGSAMGLWEVKNCTSF 638
W L D G F W G + + W +QP ++ G + G W C ++
Sbjct: 2008 WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPC-NY 2066
Query: 639 RARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRY-CYKVFSSE-----RLQ 692
+ + C++ GT E P + +L G + + +RY C + F R Q
Sbjct: 2067 QLPFTCKK--GTVACGEPPAVEHARTL-GQKKDRYEISSLVRYQCTEGFVQRHVPTIRCQ 2123
Query: 693 DKKSWVQAQGACQE 706
W + + C +
Sbjct: 2124 PSADWEEPRITCTD 2137
Score = 46.9 bits (109), Expect = 0.002
Identities = 36/143 (25%), Positives = 53/143 (36%), Gaps = 12/143 (8%)
Query: 1256 SYHGSC---PQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENV 1312
SY G Q + W F+ HCY H +A +RC+ + SI+ E
Sbjct: 1939 SYRGDLCEIDQEQCEEGWTKFQGHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEEQE 1997
Query: 1313 FVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YW 1371
FV ++ Q Y+ W+G+N G W D ++ + W P + C
Sbjct: 1998 FVNKNAQDYQ------WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVM 2051
Query: 1372 IQSNSGLWRPGACTNITMGVVCK 1394
I G W C N + CK
Sbjct: 2052 IWHERGEWNDVPC-NYQLPFTCK 2073
>gb|AAA41836.1| (M13518) proteoglycan [Rattus norvegicus]
Length = 269
Score = 118 bits (294), Expect = 4e-25
Identities = 54/127 (42%), Positives = 73/127 (56%), Gaps = 4/127 (3%)
Query: 381 ECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEEL 440
+CE W FQGHCYR ++ +W ++++ C L SI + E EF+ K + +
Sbjct: 58 QCEEGWTKFQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQ---DYQ 114
Query: 441 WIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQS 499
WIGLND ++ +F WSDG + F W P +P+NF + EDCV IW G WND PCN
Sbjct: 115 WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPCNYQ 174
Query: 500 LPSICKK 506
LP CKK
Sbjct: 175 LPFTCKK 181
Score = 87.0 bits (212), Expect = 1e-15
Identities = 49/137 (35%), Positives = 68/137 (48%), Gaps = 8/137 (5%)
Query: 235 CETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSS 294
CE W K Q CY+ +F +W +A C +Q + L SI EQ ++N Y
Sbjct: 59 CEEGWTKFQ--GHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQ- 114
Query: 295 TLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTESSGGWQNRDCS 352
WIGLND G ++WSD L++ W +QPDN + E+C V+ G W + C+
Sbjct: 115 --WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPCN 172
Query: 353 IALPYVCKKKPNATAEP 369
LP+ CKK A EP
Sbjct: 173 YQLPFTCKKGTVACGEP 189
Score = 85.0 bits (207), Expect = 6e-15
Identities = 59/198 (29%), Positives = 87/198 (43%), Gaps = 24/198 (12%)
Query: 821 DSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFS 880
D Q W +FQ Y+ F TW A+R C Q+ L+S+ + E +F++ N Q +
Sbjct: 55 DQEQCEEGWTKFQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQ 114
Query: 881 RAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR---PVGKDKKCVYMT-ASRED 936
WIGL+ +G FRW+DG + F W P +P G+D CV M R +
Sbjct: 115 -------WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGED--CVVMIWHERGE 165
Query: 937 WGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLN----KCFQ--VQGQE 990
W D C LP+ CK+ V +PP + G D + + +C + VQ
Sbjct: 166 WNDVPCNYQLPFTCKKGTVAC-GEPPAVEHARTLGQKKDRYEISSLVRYQCTEGFVQRHV 224
Query: 991 P----QSRVKWSEAQFSC 1004
P Q W E + +C
Sbjct: 225 PTIRCQPSADWEEPRITC 242
Score = 64.4 bits (154), Expect = 9e-09
Identities = 58/238 (24%), Positives = 93/238 (38%), Gaps = 34/238 (14%)
Query: 477 SLEDCVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLG 536
SL D T+ PEG +G+ AA+++ C +GWT CY
Sbjct: 33 SLTDTPTLASPEG-----------------SGETESTAADQEQ-CEEGWTKFQGHCYRHF 74
Query: 537 EDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWL 596
D+ T+ +A R C + S L +I EQ FV+ +Y W L D G F W
Sbjct: 75 PDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQ----DYQWIGLNDRTIEGDFRWS 130
Query: 597 SGDEVMYTHWNRDQPG--YSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTP 654
G + + W +QP ++ G + G W C +++ + C++ GT
Sbjct: 131 DGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPC-NYQLPFTCKK--GTVACG 187
Query: 655 ELPGPDPTPSLTGSCPQGWASDTKLRY-CYKVFSSE-----RLQDKKSWVQAQGACQE 706
E P + +L G + + +RY C + F R Q W + + C +
Sbjct: 188 EPPAVEHARTL-GQKKDRYEISSLVRYQCTEGFVQRHVPTIRCQPSADWEEPRITCTD 244
Score = 61.7 bits (147), Expect = 6e-08
Identities = 38/142 (26%), Positives = 61/142 (42%), Gaps = 19/142 (13%)
Query: 972 CPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT 1031
C W +F C++ R W +A+ C +Q++ L +I P EQ F+ + +
Sbjct: 59 CEEGWTKFQGHCYR----HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQ 114
Query: 1032 FDLWIGLH--ASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHF 1089
WIGL+ + DF+W + L + W P +P C V++ H
Sbjct: 115 ---WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGE-----DCVVMIW----HE 162
Query: 1090 TGRWDDRSCTEETHGFICQKGT 1111
G W+D C + F C+KGT
Sbjct: 163 RGEWNDVPCNYQL-PFTCKKGT 183
Score = 60.9 bits (145), Expect = 1e-07
Identities = 50/167 (29%), Positives = 78/167 (45%), Gaps = 33/167 (19%)
Query: 653 TPELPGPD------PTPSLTGSCPQGWASDTKLR-YCYKVFSSERLQDKKSWVQAQGACQ 705
TP L P+ T + C +GW TK + +CY+ F D+++WV A+ C+
Sbjct: 37 TPTLASPEGSGETESTAADQEQCEEGW---TKFQGHCYRHFP-----DRETWVDAERRCR 88
Query: 706 ELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGV 765
E + L S+ + EE+ FV NK + Q + WIGLN R G +RWSDG
Sbjct: 89 EQQSHLSSIVTPEEQEFV----NK---------NAQDYQWIGLNDRTIEG--DFRWSDGH 133
Query: 766 GFSYHNFDRSRHDDDDIRG--CAVLDLASL-QWVAMQCDTQLDWICK 809
+ + ++ D+ G C V+ +W + C+ QL + CK
Sbjct: 134 SLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPCNYQLPFTCK 180
Score = 46.5 bits (108), Expect = 0.002
Identities = 33/133 (24%), Positives = 50/133 (36%), Gaps = 9/133 (6%)
Query: 1263 QGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYE 1322
Q + W F+ HCY H +A +RC+ + SI+ E FV ++ Q Y+
Sbjct: 56 QEQCEEGWTKFQGHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQ 114
Query: 1323 GQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YWIQSNSGLWRP 1381
W+G+N G W D ++ + W P + C I G W
Sbjct: 115 ------WIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWND 168
Query: 1382 GACTNITMGVVCK 1394
C N + CK
Sbjct: 169 VPC-NYQLPFTCK 180
>ref|XP_007700.1| aggrecan 1, isoform 2 precursor [Homo sapiens]
Length = 2459
Score = 118 bits (292), Expect = 6e-25
Identities = 83/266 (31%), Positives = 121/266 (45%), Gaps = 29/266 (10%)
Query: 267 EQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLK-YLNWESD 325
E G + T ++T I+G L+G++S L + ++ W P + +L ES
Sbjct: 2109 EAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESS 2168
Query: 326 QPDNPSEENCGVIRTES--------SGGWQNRDCSIALPYV--CKKKP--NATAEPT--- 370
EE V S S W+ S A C ++P T + T
Sbjct: 2169 SLLYSGEETHTVETATSPTDASIPASPEWKRESESTAAAPARSCAEEPCGAGTCKETEGH 2228
Query: 371 -----PPD---RWANVKVE-CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIH 421
PP N+ E CE W +QGHCYR ++ +W ++++ C L SI
Sbjct: 2229 VICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIV 2288
Query: 422 SMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDC 481
+ E EF+ + + WIGLND ++ +F WSDG + F +W P +P+NF + EDC
Sbjct: 2289 TPEEQEFVNNNAQ---DYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDC 2345
Query: 482 VT-IWGPEGRWNDSPCNQSLPSICKK 506
V IW +G WND PCN LP CKK
Sbjct: 2346 VVMIWHEKGEWNDVPCNYHLPFTCKK 2371
Score = 99.5 bits (244), Expect = 3e-19
Identities = 57/172 (33%), Positives = 82/172 (47%), Gaps = 12/172 (6%)
Query: 200 GCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSW 259
G + +GH+ C Y + C I CE W+K Q CY+ +F +W
Sbjct: 2218 GAGTCKETEGHVICLCPPGYTGEH----CNIDQEVCEEGWNKYQ--GHCYR-HFPDRETW 2270
Query: 260 REAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKY 319
+A C +Q + L SI EQ ++N Y WIGLND G ++WSD P+++
Sbjct: 2271 VDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHPMQF 2327
Query: 320 LNWESDQPDN--PSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEP 369
NW +QPDN + E+C V+ G W + C+ LP+ CKK A EP
Sbjct: 2328 ENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEP 2379
Score = 81.5 bits (198), Expect = 6e-14
Identities = 63/219 (28%), Positives = 97/219 (43%), Gaps = 25/219 (11%)
Query: 801 DTQLDWICKIPRG-TDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAE 859
+T+ IC P G T D W ++Q Y+ F TW A+R C Q+
Sbjct: 2224 ETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSH 2283
Query: 860 LTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR 919
L+S+ + E +F+++N Q + WIGL+ +G FRW+DG + F +W P +P
Sbjct: 2284 LSSIVTPEEQEFVNNNAQDYQ-------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPD 2336
Query: 920 ---PVGKDKKCVYMT-ASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSD 975
G+D CV M + +W D C LP+ CK+ V +PP + G D
Sbjct: 2337 NFFAAGED--CVVMIWHEKGEWNDVPCNYHLPFTCKKGTVAC-GEPPVVEHARTFGQKKD 2393
Query: 976 WIQFLN----KCFQ--VQGQEPQSRVK----WSEAQFSC 1004
+ + +C + VQ P R + W E Q +C
Sbjct: 2394 RYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITC 2432
Score = 66.0 bits (158), Expect = 3e-09
Identities = 46/180 (25%), Positives = 74/180 (40%), Gaps = 31/180 (17%)
Query: 934 REDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQS 993
+E G CL Y + N+ +E C W ++ C++
Sbjct: 2223 KETEGHVICLCPPGYTGEHCNIDQEV------------CEEGWNKYQGHCYR----HFPD 2266
Query: 994 RVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLH--ASQRDFQWVEQE 1051
R W +A+ C +Q++ L +I P EQ F+ + + WIGL+ + DF+W +
Sbjct: 2267 RETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGH 2323
Query: 1052 PLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGT 1111
P+ + NW P +P A C V++ H G W+D C F C+KGT
Sbjct: 2324 PMQFENWRPNQPDNFFAAGE-----DCVVMIW----HEKGEWNDVPCNYHL-PFTCKKGT 2373
Score = 59.3 bits (141), Expect = 3e-07
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 25/144 (17%)
Query: 669 CPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLN 728
C +GW + +CY+ F D+++WV A+ C+E + L S+ + EE+ FV N
Sbjct: 2249 CEEGW--NKYQGHCYRHFP-----DRETWVDAERRCREQQSHLSSIVTPEEQEFVNN--- 2298
Query: 729 KIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--CA 786
+ Q + WIGLN R G +RWSDG + N+ ++ D+ G C
Sbjct: 2299 ----------NAQDYQWIGLNDRTIEG--DFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 2346
Query: 787 VLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ L + CK
Sbjct: 2347 VMIWHEKGEWNDVPCNYHLPFTCK 2370
Score = 58.9 bits (140), Expect = 4e-07
Identities = 48/194 (24%), Positives = 78/194 (39%), Gaps = 16/194 (8%)
Query: 521 CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYF 580
C +GW + CY D+ T+ +A R C + S L +I EQ FV+ N +Y
Sbjct: 2249 CEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVN----NNAQDYQ 2304
Query: 581 WTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG--YSRGGCVALATGSAMGLWEVKNCTSF 638
W L D G F W G + + +W +QP ++ G + G W C ++
Sbjct: 2305 WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPC-NY 2363
Query: 639 RARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRY-CYKVFSSE-----RLQ 692
+ C++ GT E P + + G + ++ +RY C + F R Q
Sbjct: 2364 HLPFTCKK--GTVACGEPPVVEHARTF-GQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQ 2420
Query: 693 DKKSWVQAQGACQE 706
W + Q C +
Sbjct: 2421 PSGHWEEPQITCTD 2434
Score = 51.2 bits (120), Expect = 9e-05
Identities = 36/145 (24%), Positives = 54/145 (36%), Gaps = 9/145 (6%)
Query: 1251 PPRRISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEME 1310
PP H + Q + + W ++ HCY H +A +RC+ + SI+ E
Sbjct: 2234 PPGYTGEHCNIDQEVCEEGWNKYQGHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEE 2292
Query: 1311 NVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC- 1369
FV + Q Y+ W+G+N G W D + + NW P + C
Sbjct: 2293 QEFVNNNAQDYQ------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 2346
Query: 1370 YWIQSNSGLWRPGACTNITMGVVCK 1394
I G W C N + CK
Sbjct: 2347 VMIWHEKGEWNDVPC-NYHLPFTCK 2370
Score = 34.8 bits (78), Expect = 7.5
Identities = 17/69 (24%), Positives = 28/69 (39%), Gaps = 3/69 (4%)
Query: 1146 WHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLN 1205
W DA C + L+ + P Q F+ A+ + WIGL + W P+
Sbjct: 2270 WVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHPMQ 2326
Query: 1206 YVGWQDGEP 1214
+ W+ +P
Sbjct: 2327 FENWRPNQP 2335
>gb|AAB06238.2| (U65989) articular cartilage aggrecan precursor [Canis familiaris]
Length = 2333
Score = 118 bits (292), Expect = 6e-25
Identities = 55/126 (43%), Positives = 72/126 (56%), Gaps = 4/126 (3%)
Query: 382 CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELW 441
CE W FQGHCYR ++ SW +++ C L SI + E EF+ + + W
Sbjct: 2123 CEEGWTKFQGHCYRYFPDRESWVDAESRCRAQQSHLSSIVTPEEQEFVNNNAQ---DYQW 2179
Query: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSL 500
IGLND ++ +F WSDG + F +W P +P+NF S EDCV IW +G WND PCN L
Sbjct: 2180 IGLNDRTIEGDFRWSDGHSLQFENWRPNQPDNFFVSGEDCVVMIWHEKGEWNDVPCNYYL 2239
Query: 501 PSICKK 506
P CKK
Sbjct: 2240 PFTCKK 2245
Score = 94.8 bits (232), Expect = 7e-18
Identities = 54/148 (36%), Positives = 72/148 (48%), Gaps = 8/148 (5%)
Query: 224 RWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQT 283
R C I CE W K Q CY++ F SW +A + C Q + L SI EQ
Sbjct: 2112 RGDLCEIDQELCEEGWTKFQ--GHCYRY-FPDRESWVDAESRCRAQQSHLSSIVTPEEQE 2168
Query: 284 YINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTE 341
++N Y WIGLND G ++WSD L++ NW +QPDN S E+C V+
Sbjct: 2169 FVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHSLQFENWRPNQPDNFFVSGEDCVVMIWH 2225
Query: 342 SSGGWQNRDCSIALPYVCKKKPNATAEP 369
G W + C+ LP+ CKK A +P
Sbjct: 2226 EKGEWNDVPCNYYLPFTCKKGTVACGDP 2253
Score = 79.2 bits (192), Expect = 3e-13
Identities = 42/131 (32%), Positives = 67/131 (51%), Gaps = 13/131 (9%)
Query: 829 WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWW 888
W +FQ Y++F +W A+ C Q+ L+S+ + E +F+++N Q + W
Sbjct: 2127 WTKFQGHCYRYFPDRESWVDAESRCRAQQSHLSSIVTPEEQEFVNNNAQDYQ-------W 2179
Query: 889 IGLHTSESDGRFRWTDGSIINFISWAPGKPRPV---GKDKKCVYMT-ASREDWGDQRCLT 944
IGL+ +G FRW+DG + F +W P +P G+D CV M + +W D C
Sbjct: 2180 IGLNDRTIEGDFRWSDGHSLQFENWRPNQPDNFFVSGED--CVVMIWHEKGEWNDVPCNY 2237
Query: 945 ALPYICKRSNV 955
LP+ CK+ V
Sbjct: 2238 YLPFTCKKGTV 2248
Score = 63.2 bits (151), Expect = 2e-08
Identities = 44/145 (30%), Positives = 70/145 (47%), Gaps = 27/145 (18%)
Query: 669 CPQGWASDTKLR-YCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANML 727
C +GW TK + +CY+ F D++SWV A+ C+ + L S+ + EE+ FV N
Sbjct: 2123 CEEGW---TKFQGHCYRYFP-----DRESWVDAESRCRAQQSHLSSIVTPEEQEFVNN-- 2172
Query: 728 NKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--C 785
+ Q + WIGLN R G +RWSDG + N+ ++ D+ + G C
Sbjct: 2173 -----------NAQDYQWIGLNDRTIEG--DFRWSDGHSLQFENWRPNQPDNFFVSGEDC 2219
Query: 786 AVLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ L + CK
Sbjct: 2220 VVMIWHEKGEWNDVPCNYYLPFTCK 2244
Score = 62.1 bits (148), Expect = 5e-08
Identities = 41/142 (28%), Positives = 63/142 (43%), Gaps = 19/142 (13%)
Query: 972 CPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT 1031
C W +F C++ R W +A+ C Q++ L +I P EQ F+ + +
Sbjct: 2123 CEEGWTKFQGHCYRYF----PDRESWVDAESRCRAQQSHLSSIVTPEEQEFVNNNAQDYQ 2178
Query: 1032 FDLWIGLH--ASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHF 1089
WIGL+ + DF+W + L + NW P +P + SG C V++ H
Sbjct: 2179 ---WIGLNDRTIEGDFRWSDGHSLQFENWRPNQPD--NFFVSGE---DCVVMIW----HE 2226
Query: 1090 TGRWDDRSCTEETHGFICQKGT 1111
G W+D C F C+KGT
Sbjct: 2227 KGEWNDVPCNYYL-PFTCKKGT 2247
Score = 53.5 bits (126), Expect = 2e-05
Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Query: 521 CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYF 580
C +GWT CY D+ ++ +A C S L +I EQ FV+ N +Y
Sbjct: 2123 CEEGWTKFQGHCYRYFPDRESWVDAESRCRAQQSHLSSIVTPEEQEFVN----NNAQDYQ 2178
Query: 581 WTALQDLNSTGSFFWLSGDEVMYTHWNRDQP 611
W L D G F W G + + +W +QP
Sbjct: 2179 WIGLNDRTIEGDFRWSDGHSLQFENWRPNQP 2209
Score = 52.7 bits (124), Expect = 3e-05
Identities = 38/143 (26%), Positives = 55/143 (37%), Gaps = 12/143 (8%)
Query: 1256 SYHGSC---PQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENV 1312
SY G Q L + W F+ HCY + + +A RC+ + SI+ E
Sbjct: 2110 SYRGDLCEIDQELCEEGWTKFQGHCYRYFPDRE-SWVDAESRCRAQQSHLSSIVTPEEQE 2168
Query: 1313 FVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YW 1371
FV + Q Y+ W+G+N G W D ++ + NW P +S C
Sbjct: 2169 FVNNNAQDYQ------WIGLNDRTIEGDFRWSDGHSLQFENWRPNQPDNFFVSGEDCVVM 2222
Query: 1372 IQSNSGLWRPGACTNITMGVVCK 1394
I G W C N + CK
Sbjct: 2223 IWHEKGEWNDVPC-NYYLPFTCK 2244
>sp|P13608|PGCA_BOVIN AGGRECAN CORE PROTEIN PRECURSOR (CARTILAGE-SPECIFIC PROTEOGLYCAN CORE
PROTEIN) (CSPCP)
Length = 2364
Score = 118 bits (292), Expect = 6e-25
Identities = 77/267 (28%), Positives = 117/267 (42%), Gaps = 28/267 (10%)
Query: 265 SCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKY-LNWE 323
S E G+ + ++T +G L+G++S L I ++ W P + L E
Sbjct: 2013 SVEASGSPSATPLASGDRTDTSGDLSGHTSGLDIVISTTIPESEWTQQTQRPAEARLEIE 2072
Query: 324 SDQPDNPSEEN---------CGVIRTESSGGWQNRDCSIALPYVCKKKP----------- 363
S P + EE+ S+GG + + + C P
Sbjct: 2073 SSSPVHSGEESQTADTATSPTDASIPASAGGTDDSEATTTDIDECLSSPCLNGATCVDAI 2132
Query: 364 ---NATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSI 420
P+ ++ CE W FQGHCYR ++ +W +++ C + L SI
Sbjct: 2133 DSFTCLCLPSYQGDVCEIQKLCEEGWTKFQGHCYRHFPDRATWVDAESQCRKQQSHLSSI 2192
Query: 421 HSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLED 480
+ E EF+ + + WIGLND ++ +F WSDG + F +W P +P+NF + ED
Sbjct: 2193 VTPEEQEFVNNNAQ---DYQWIGLNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGED 2249
Query: 481 CVT-IWGPEGRWNDSPCNQSLPSICKK 506
CV IW +G WND PCN LP CKK
Sbjct: 2250 CVVMIWHEKGEWNDVPCNYQLPFTCKK 2276
Score = 95.2 bits (233), Expect = 5e-18
Identities = 61/192 (31%), Positives = 90/192 (46%), Gaps = 24/192 (12%)
Query: 235 CETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSS 294
CE W K Q CY+ +F +W +A + C +Q + L SI EQ ++N Y
Sbjct: 2154 CEEGWTKFQ--GHCYR-HFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQDYQ- 2209
Query: 295 TLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTESSGGWQNRDCS 352
WIGLND G ++WSD L++ NW +QPDN + E+C V+ G W + C+
Sbjct: 2210 --WIGLNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGEDCVVMIWHEKGEWNDVPCN 2267
Query: 353 IALPYVCKKKPNATAEP----------TPPDRW---ANVKVECEPSWQPFQGHCYRLQAE 399
LP+ CKK A EP DR+ A V+ +C + QGH ++ +
Sbjct: 2268 YQLPFTCKKGTVACGEPPVVEHARIFGQKKDRYEINALVRYQCTEGF--IQGHVPTIRCQ 2325
Query: 400 KRS-WQESKKAC 410
W+E + C
Sbjct: 2326 PSGHWEEPRITC 2337
Score = 84.3 bits (205), Expect = 1e-14
Identities = 55/190 (28%), Positives = 89/190 (45%), Gaps = 24/190 (12%)
Query: 829 WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWW 888
W +FQ Y+ F +TW A+ C Q+ L+S+ + E +F+++N Q + W
Sbjct: 2158 WTKFQGHCYRHFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQDYQ-------W 2210
Query: 889 IGLHTSESDGRFRWTDGSIINFISWAPGKPR---PVGKDKKCVYMT-ASREDWGDQRCLT 944
IGL+ +G FRW+DG + F +W P +P G+D CV M + +W D C
Sbjct: 2211 IGLNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGED--CVVMIWHEKGEWNDVPCNY 2268
Query: 945 ALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQF----LNKCFQ--VQGQEPQSRVK-- 996
LP+ CK+ V +PP + + G D + +C + +QG P R +
Sbjct: 2269 QLPFTCKKGTVAC-GEPPVVEHARIFGQKKDRYEINALVRYQCTEGFIQGHVPTIRCQPS 2327
Query: 997 --WSEAQFSC 1004
W E + +C
Sbjct: 2328 GHWEEPRITC 2337
Score = 64.8 bits (155), Expect = 7e-09
Identities = 39/142 (27%), Positives = 62/142 (43%), Gaps = 19/142 (13%)
Query: 972 CPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT 1031
C W +F C++ R W +A+ C +Q++ L +I P EQ F+ + +
Sbjct: 2154 CEEGWTKFQGHCYR----HFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQDYQ 2209
Query: 1032 FDLWIGLHAS--QRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHF 1089
WIGL+ + DF+W + L + NW P +P C V++ H
Sbjct: 2210 ---WIGLNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGE-----DCVVMIW----HE 2257
Query: 1090 TGRWDDRSCTEETHGFICQKGT 1111
G W+D C + F C+KGT
Sbjct: 2258 KGEWNDVPCNYQL-PFTCKKGT 2278
Score = 60.9 bits (145), Expect = 1e-07
Identities = 43/145 (29%), Positives = 70/145 (47%), Gaps = 27/145 (18%)
Query: 669 CPQGWASDTKLR-YCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANML 727
C +GW TK + +CY+ F D+ +WV A+ C++ + L S+ + EE+ FV N
Sbjct: 2154 CEEGW---TKFQGHCYRHFP-----DRATWVDAESQCRKQQSHLSSIVTPEEQEFVNN-- 2203
Query: 728 NKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--C 785
+ Q + WIGLN + G +RWSDG + N+ ++ D+ G C
Sbjct: 2204 -----------NAQDYQWIGLNDKTIEG--DFRWSDGHSLQFENWRPNQPDNFFATGEDC 2250
Query: 786 AVLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ QL + CK
Sbjct: 2251 VVMIWHEKGEWNDVPCNYQLPFTCK 2275
Score = 57.4 bits (136), Expect = 1e-06
Identities = 38/139 (27%), Positives = 58/139 (41%), Gaps = 9/139 (6%)
Query: 521 CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYF 580
C +GWT CY D+ T+ +A C S L +I EQ FV+ N +Y
Sbjct: 2154 CEEGWTKFQGHCYRHFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVN----NNAQDYQ 2209
Query: 581 WTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG--YSRGGCVALATGSAMGLWEVKNCTSF 638
W L D G F W G + + +W +QP ++ G + G W C ++
Sbjct: 2210 WIGLNDKTIEGDFRWSDGHSLQFENWRPNQPDNFFATGEDCVVMIWHEKGEWNDVPC-NY 2268
Query: 639 RARYICRQSLGTPVTPELP 657
+ + C++ GT E P
Sbjct: 2269 QLPFTCKK--GTVACGEPP 2285
Score = 52.7 bits (124), Expect = 3e-05
Identities = 44/177 (24%), Positives = 64/177 (35%), Gaps = 27/177 (15%)
Query: 1219 GCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGSCPQGLADSAWIPFREHCY 1278
G T VD ++ T C QG VC + Q L + W F+ HCY
Sbjct: 2125 GATCVDAIDSF-TCLCLPSYQGDVCEI-----------------QKLCEEGWTKFQGHCY 2166
Query: 1279 SFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFNPKG 1338
H +A +C++ + SI+ E FV + Q Y+ W+G+N
Sbjct: 2167 R-HFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQDYQ------WIGLNDKTIE 2219
Query: 1339 GTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YWIQSNSGLWRPGACTNITMGVVCK 1394
G W D ++ + NW P + C I G W C N + CK
Sbjct: 2220 GDFRWSDGHSLQFENWRPNQPDNFFATGEDCVVMIWHEKGEWNDVPC-NYQLPFTCK 2275
>sp||PGCA_CANFA_2 [Segment 2 of 2] AGGRECAN CORE PROTEIN (CARTILAGE-SPECIFIC
PROTEOGLYCAN CORE PROTEIN) (CSPCP)
Length = 504
Score = 118 bits (292), Expect = 6e-25
Identities = 55/126 (43%), Positives = 72/126 (56%), Gaps = 4/126 (3%)
Query: 382 CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELW 441
CE W FQGHCYR ++ SW +++ C L SI + E EF+ + + W
Sbjct: 294 CEEGWTKFQGHCYRYFPDRESWVDAESRCRAQQSHLSSIVTPEEQEFVNNNAQ---DYQW 350
Query: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSL 500
IGLND ++ +F WSDG + F +W P +P+NF S EDCV IW +G WND PCN L
Sbjct: 351 IGLNDRTIEGDFRWSDGHSLQFENWRPNQPDNFFVSGEDCVVMIWHEKGEWNDVPCNYYL 410
Query: 501 PSICKK 506
P CKK
Sbjct: 411 PFTCKK 416
Score = 94.8 bits (232), Expect = 7e-18
Identities = 54/148 (36%), Positives = 72/148 (48%), Gaps = 8/148 (5%)
Query: 224 RWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQT 283
R C I CE W K Q CY++ F SW +A + C Q + L SI EQ
Sbjct: 283 RGDLCEIDQELCEEGWTKFQ--GHCYRY-FPDRESWVDAESRCRAQQSHLSSIVTPEEQE 339
Query: 284 YINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTE 341
++N Y WIGLND G ++WSD L++ NW +QPDN S E+C V+
Sbjct: 340 FVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHSLQFENWRPNQPDNFFVSGEDCVVMIWH 396
Query: 342 SSGGWQNRDCSIALPYVCKKKPNATAEP 369
G W + C+ LP+ CKK A +P
Sbjct: 397 EKGEWNDVPCNYYLPFTCKKGTVACGDP 424
Score = 79.2 bits (192), Expect = 3e-13
Identities = 42/131 (32%), Positives = 67/131 (51%), Gaps = 13/131 (9%)
Query: 829 WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWW 888
W +FQ Y++F +W A+ C Q+ L+S+ + E +F+++N Q + W
Sbjct: 298 WTKFQGHCYRYFPDRESWVDAESRCRAQQSHLSSIVTPEEQEFVNNNAQDYQ-------W 350
Query: 889 IGLHTSESDGRFRWTDGSIINFISWAPGKPRPV---GKDKKCVYMT-ASREDWGDQRCLT 944
IGL+ +G FRW+DG + F +W P +P G+D CV M + +W D C
Sbjct: 351 IGLNDRTIEGDFRWSDGHSLQFENWRPNQPDNFFVSGED--CVVMIWHEKGEWNDVPCNY 408
Query: 945 ALPYICKRSNV 955
LP+ CK+ V
Sbjct: 409 YLPFTCKKGTV 419
Score = 63.2 bits (151), Expect = 2e-08
Identities = 44/145 (30%), Positives = 70/145 (47%), Gaps = 27/145 (18%)
Query: 669 CPQGWASDTKLR-YCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANML 727
C +GW TK + +CY+ F D++SWV A+ C+ + L S+ + EE+ FV N
Sbjct: 294 CEEGW---TKFQGHCYRYFP-----DRESWVDAESRCRAQQSHLSSIVTPEEQEFVNN-- 343
Query: 728 NKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--C 785
+ Q + WIGLN R G +RWSDG + N+ ++ D+ + G C
Sbjct: 344 -----------NAQDYQWIGLNDRTIEG--DFRWSDGHSLQFENWRPNQPDNFFVSGEDC 390
Query: 786 AVLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ L + CK
Sbjct: 391 VVMIWHEKGEWNDVPCNYYLPFTCK 415
Score = 62.1 bits (148), Expect = 5e-08
Identities = 41/142 (28%), Positives = 63/142 (43%), Gaps = 19/142 (13%)
Query: 972 CPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT 1031
C W +F C++ R W +A+ C Q++ L +I P EQ F+ + +
Sbjct: 294 CEEGWTKFQGHCYRYF----PDRESWVDAESRCRAQQSHLSSIVTPEEQEFVNNNAQDYQ 349
Query: 1032 FDLWIGLH--ASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHF 1089
WIGL+ + DF+W + L + NW P +P + SG C V++ H
Sbjct: 350 ---WIGLNDRTIEGDFRWSDGHSLQFENWRPNQPD--NFFVSGE---DCVVMIW----HE 397
Query: 1090 TGRWDDRSCTEETHGFICQKGT 1111
G W+D C F C+KGT
Sbjct: 398 KGEWNDVPCNYYL-PFTCKKGT 418
Score = 53.5 bits (126), Expect = 2e-05
Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Query: 521 CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYF 580
C +GWT CY D+ ++ +A C S L +I EQ FV+ N +Y
Sbjct: 294 CEEGWTKFQGHCYRYFPDRESWVDAESRCRAQQSHLSSIVTPEEQEFVN----NNAQDYQ 349
Query: 581 WTALQDLNSTGSFFWLSGDEVMYTHWNRDQP 611
W L D G F W G + + +W +QP
Sbjct: 350 WIGLNDRTIEGDFRWSDGHSLQFENWRPNQP 380
Score = 52.7 bits (124), Expect = 3e-05
Identities = 38/143 (26%), Positives = 55/143 (37%), Gaps = 12/143 (8%)
Query: 1256 SYHGSC---PQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENV 1312
SY G Q L + W F+ HCY + + +A RC+ + SI+ E
Sbjct: 281 SYRGDLCEIDQELCEEGWTKFQGHCYRYFPDRE-SWVDAESRCRAQQSHLSSIVTPEEQE 339
Query: 1313 FVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YW 1371
FV + Q Y+ W+G+N G W D ++ + NW P +S C
Sbjct: 340 FVNNNAQDYQ------WIGLNDRTIEGDFRWSDGHSLQFENWRPNQPDNFFVSGEDCVVM 393
Query: 1372 IQSNSGLWRPGACTNITMGVVCK 1394
I G W C N + CK
Sbjct: 394 IWHEKGEWNDVPC-NYYLPFTCK 415
>pir||S08042 proteoglycan core protein long splice form, cartilage - human
(fragment)
Length = 638
Score = 118 bits (292), Expect = 6e-25
Identities = 83/266 (31%), Positives = 121/266 (45%), Gaps = 29/266 (10%)
Query: 267 EQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLK-YLNWESD 325
E G + T ++T I+G L+G++S L + ++ W P + +L ES
Sbjct: 288 EAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESS 347
Query: 326 QPDNPSEENCGVIRTES--------SGGWQNRDCSIALPYV--CKKKP--NATAEPT--- 370
EE V S S W+ S A C ++P T + T
Sbjct: 348 SLLYSGEETHTVETATSPTDASIPASPEWKRESESTAAAPARSCAEEPCGAGTCKETEGH 407
Query: 371 -----PPD---RWANVKVE-CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIH 421
PP N+ E CE W +QGHCYR ++ +W ++++ C L SI
Sbjct: 408 VICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIV 467
Query: 422 SMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDC 481
+ E EF+ + + WIGLND ++ +F WSDG + F +W P +P+NF + EDC
Sbjct: 468 TPEEQEFVNNNAQ---DYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDC 524
Query: 482 VT-IWGPEGRWNDSPCNQSLPSICKK 506
V IW +G WND PCN LP CKK
Sbjct: 525 VVMIWHEKGEWNDVPCNYHLPFTCKK 550
Score = 99.5 bits (244), Expect = 3e-19
Identities = 57/172 (33%), Positives = 82/172 (47%), Gaps = 12/172 (6%)
Query: 200 GCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSW 259
G + +GH+ C Y + C I CE W+K Q CY+ +F +W
Sbjct: 397 GAGTCKETEGHVICLCPPGYTGEH----CNIDQEVCEEGWNKYQ--GHCYR-HFPDRETW 449
Query: 260 REAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKY 319
+A C +Q + L SI EQ ++N Y WIGLND G ++WSD P+++
Sbjct: 450 VDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHPMQF 506
Query: 320 LNWESDQPDN--PSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEP 369
NW +QPDN + E+C V+ G W + C+ LP+ CKK A EP
Sbjct: 507 ENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEP 558
Score = 80.0 bits (194), Expect = 2e-13
Identities = 50/160 (31%), Positives = 76/160 (47%), Gaps = 14/160 (8%)
Query: 801 DTQLDWICKIPRG-TDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAE 859
+T+ IC P G T D W ++Q Y+ F TW A+R C Q+
Sbjct: 403 ETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSH 462
Query: 860 LTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR 919
L+S+ + E +F+++N Q + WIGL+ +G FRW+DG + F +W P +P
Sbjct: 463 LSSIVTPEEQEFVNNNAQDYQ-------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPD 515
Query: 920 ---PVGKDKKCVYMT-ASREDWGDQRCLTALPYICKRSNV 955
G+D CV M + +W D C LP+ CK+ V
Sbjct: 516 NFFAAGED--CVVMIWHEKGEWNDVPCNYHLPFTCKKGTV 553
Score = 66.0 bits (158), Expect = 3e-09
Identities = 46/180 (25%), Positives = 74/180 (40%), Gaps = 31/180 (17%)
Query: 934 REDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQS 993
+E G CL Y + N+ +E C W ++ C++
Sbjct: 402 KETEGHVICLCPPGYTGEHCNIDQEV------------CEEGWNKYQGHCYR----HFPD 445
Query: 994 RVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLH--ASQRDFQWVEQE 1051
R W +A+ C +Q++ L +I P EQ F+ + + WIGL+ + DF+W +
Sbjct: 446 RETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGH 502
Query: 1052 PLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGT 1111
P+ + NW P +P A C V++ H G W+D C F C+KGT
Sbjct: 503 PMQFENWRPNQPDNFFAAGE-----DCVVMIW----HEKGEWNDVPCNYHL-PFTCKKGT 552
Score = 59.3 bits (141), Expect = 3e-07
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 25/144 (17%)
Query: 669 CPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLN 728
C +GW + +CY+ F D+++WV A+ C+E + L S+ + EE+ FV N
Sbjct: 428 CEEGW--NKYQGHCYRHFP-----DRETWVDAERRCREQQSHLSSIVTPEEQEFVNN--- 477
Query: 729 KIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--CA 786
+ Q + WIGLN R G +RWSDG + N+ ++ D+ G C
Sbjct: 478 ----------NAQDYQWIGLNDRTIEG--DFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 525
Query: 787 VLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ L + CK
Sbjct: 526 VMIWHEKGEWNDVPCNYHLPFTCK 549
Score = 58.6 bits (139), Expect = 5e-07
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 9/139 (6%)
Query: 521 CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYF 580
C +GW + CY D+ T+ +A R C + S L +I EQ FV+ N +Y
Sbjct: 428 CEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVN----NNAQDYQ 483
Query: 581 WTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG--YSRGGCVALATGSAMGLWEVKNCTSF 638
W L D G F W G + + +W +QP ++ G + G W C ++
Sbjct: 484 WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPC-NY 542
Query: 639 RARYICRQSLGTPVTPELP 657
+ C++ GT E P
Sbjct: 543 HLPFTCKK--GTVACGEPP 559
Score = 51.2 bits (120), Expect = 9e-05
Identities = 36/145 (24%), Positives = 54/145 (36%), Gaps = 9/145 (6%)
Query: 1251 PPRRISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEME 1310
PP H + Q + + W ++ HCY H +A +RC+ + SI+ E
Sbjct: 413 PPGYTGEHCNIDQEVCEEGWNKYQGHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEE 471
Query: 1311 NVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC- 1369
FV + Q Y+ W+G+N G W D + + NW P + C
Sbjct: 472 QEFVNNNAQDYQ------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 525
Query: 1370 YWIQSNSGLWRPGACTNITMGVVCK 1394
I G W C N + CK
Sbjct: 526 VMIWHEKGEWNDVPC-NYHLPFTCK 549
Score = 34.8 bits (78), Expect = 7.5
Identities = 17/69 (24%), Positives = 28/69 (39%), Gaps = 3/69 (4%)
Query: 1146 WHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLN 1205
W DA C + L+ + P Q F+ A+ + WIGL + W P+
Sbjct: 449 WVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHPMQ 505
Query: 1206 YVGWQDGEP 1214
+ W+ +P
Sbjct: 506 FENWRPNQP 514
>sp|P16112|PGCA_HUMAN AGGRECAN CORE PROTEIN PRECURSOR (CARTILAGE-SPECIFIC PROTEOGLYCAN CORE
PROTEIN) (CSPCP) (CHONDROITIN SULFATE PROTEOGLYCAN CORE
PROTEIN 1)
Length = 2415
Score = 118 bits (292), Expect = 6e-25
Identities = 83/266 (31%), Positives = 121/266 (45%), Gaps = 29/266 (10%)
Query: 267 EQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLK-YLNWESD 325
E G + T ++T I+G L+G++S L + ++ W P + +L ES
Sbjct: 2065 EAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESS 2124
Query: 326 QPDNPSEENCGVIRTES--------SGGWQNRDCSIALPYV--CKKKP--NATAEPT--- 370
EE V S S W+ S A C ++P T + T
Sbjct: 2125 SLLYSGEETHTVETATSPTDASIPASPEWKRESESTAAAPARSCAEEPCGAGTCKETEGH 2184
Query: 371 -----PPD---RWANVKVE-CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIH 421
PP N+ E CE W +QGHCYR ++ +W ++++ C L SI
Sbjct: 2185 VICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIV 2244
Query: 422 SMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDC 481
+ E EF+ + + WIGLND ++ +F WSDG + F +W P +P+NF + EDC
Sbjct: 2245 TPEEQEFVNNNAQ---DYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDC 2301
Query: 482 VT-IWGPEGRWNDSPCNQSLPSICKK 506
V IW +G WND PCN LP CKK
Sbjct: 2302 VVMIWHEKGEWNDVPCNYHLPFTCKK 2327
Score = 99.5 bits (244), Expect = 3e-19
Identities = 57/172 (33%), Positives = 82/172 (47%), Gaps = 12/172 (6%)
Query: 200 GCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSW 259
G + +GH+ C Y + C I CE W+K Q CY+ +F +W
Sbjct: 2174 GAGTCKETEGHVICLCPPGYTGEH----CNIDQEVCEEGWNKYQ--GHCYR-HFPDRETW 2226
Query: 260 REAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKY 319
+A C +Q + L SI EQ ++N Y WIGLND G ++WSD P+++
Sbjct: 2227 VDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHPMQF 2283
Query: 320 LNWESDQPDN--PSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEP 369
NW +QPDN + E+C V+ G W + C+ LP+ CKK A EP
Sbjct: 2284 ENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEP 2335
Score = 80.0 bits (194), Expect = 2e-13
Identities = 50/160 (31%), Positives = 76/160 (47%), Gaps = 14/160 (8%)
Query: 801 DTQLDWICKIPRG-TDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAE 859
+T+ IC P G T D W ++Q Y+ F TW A+R C Q+
Sbjct: 2180 ETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSH 2239
Query: 860 LTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR 919
L+S+ + E +F+++N Q + WIGL+ +G FRW+DG + F +W P +P
Sbjct: 2240 LSSIVTPEEQEFVNNNAQDYQ-------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPD 2292
Query: 920 ---PVGKDKKCVYMT-ASREDWGDQRCLTALPYICKRSNV 955
G+D CV M + +W D C LP+ CK+ V
Sbjct: 2293 NFFAAGED--CVVMIWHEKGEWNDVPCNYHLPFTCKKGTV 2330
Score = 66.0 bits (158), Expect = 3e-09
Identities = 46/180 (25%), Positives = 74/180 (40%), Gaps = 31/180 (17%)
Query: 934 REDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQS 993
+E G CL Y + N+ +E C W ++ C++
Sbjct: 2179 KETEGHVICLCPPGYTGEHCNIDQEV------------CEEGWNKYQGHCYR----HFPD 2222
Query: 994 RVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLH--ASQRDFQWVEQE 1051
R W +A+ C +Q++ L +I P EQ F+ + + WIGL+ + DF+W +
Sbjct: 2223 RETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGH 2279
Query: 1052 PLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGT 1111
P+ + NW P +P A C V++ H G W+D C F C+KGT
Sbjct: 2280 PMQFENWRPNQPDNFFAAGE-----DCVVMIW----HEKGEWNDVPCNYHL-PFTCKKGT 2329
Score = 59.3 bits (141), Expect = 3e-07
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 25/144 (17%)
Query: 669 CPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLN 728
C +GW + +CY+ F D+++WV A+ C+E + L S+ + EE+ FV N
Sbjct: 2205 CEEGW--NKYQGHCYRHFP-----DRETWVDAERRCREQQSHLSSIVTPEEQEFVNN--- 2254
Query: 729 KIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--CA 786
+ Q + WIGLN R G +RWSDG + N+ ++ D+ G C
Sbjct: 2255 ----------NAQDYQWIGLNDRTIEG--DFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 2302
Query: 787 VLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ L + CK
Sbjct: 2303 VMIWHEKGEWNDVPCNYHLPFTCK 2326
Score = 58.6 bits (139), Expect = 5e-07
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 9/139 (6%)
Query: 521 CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYF 580
C +GW + CY D+ T+ +A R C + S L +I EQ FV+ N +Y
Sbjct: 2205 CEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVN----NNAQDYQ 2260
Query: 581 WTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG--YSRGGCVALATGSAMGLWEVKNCTSF 638
W L D G F W G + + +W +QP ++ G + G W C ++
Sbjct: 2261 WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPC-NY 2319
Query: 639 RARYICRQSLGTPVTPELP 657
+ C++ GT E P
Sbjct: 2320 HLPFTCKK--GTVACGEPP 2336
Score = 51.2 bits (120), Expect = 9e-05
Identities = 36/145 (24%), Positives = 54/145 (36%), Gaps = 9/145 (6%)
Query: 1251 PPRRISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEME 1310
PP H + Q + + W ++ HCY H +A +RC+ + SI+ E
Sbjct: 2190 PPGYTGEHCNIDQEVCEEGWNKYQGHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEE 2248
Query: 1311 NVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC- 1369
FV + Q Y+ W+G+N G W D + + NW P + C
Sbjct: 2249 QEFVNNNAQDYQ------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 2302
Query: 1370 YWIQSNSGLWRPGACTNITMGVVCK 1394
I G W C N + CK
Sbjct: 2303 VMIWHEKGEWNDVPC-NYHLPFTCK 2326
Score = 34.8 bits (78), Expect = 7.5
Identities = 17/69 (24%), Positives = 28/69 (39%), Gaps = 3/69 (4%)
Query: 1146 WHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLN 1205
W DA C + L+ + P Q F+ A+ + WIGL + W P+
Sbjct: 2226 WVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHPMQ 2282
Query: 1206 YVGWQDGEP 1214
+ W+ +P
Sbjct: 2283 FENWRPNQP 2291
>ref|NP_037359.1| aggrecan 1, isoform 1 precursor; Aggrecan-1 (chondroitin sulfate
proteoglycan-1, large aggregating proteoglycan, antigen
identifies by monoclonal antibody A0122); chondroitin
sulfate proteoglycan 1, large aggregating proteoglycan
[Homo sapiens]
Length = 2415
Score = 117 bits (291), Expect = 8e-25
Identities = 83/266 (31%), Positives = 121/266 (45%), Gaps = 29/266 (10%)
Query: 267 EQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLK-YLNWESD 325
E G + T ++T I+G L+G++S L + ++ W P + +L ES
Sbjct: 2065 EAPGLASATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESS 2124
Query: 326 QPDNPSEENCGVIRTES--------SGGWQNRDCSIALPYV--CKKKP--NATAEPT--- 370
EE V S S W+ S A C ++P T + T
Sbjct: 2125 SLLYSGEETHTVETATSPTDASIPASPEWKRESESTAAAPARSCAEEPCGAGTCKETEGH 2184
Query: 371 -----PPD---RWANVKVE-CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIH 421
PP N+ E CE W +QGHCYR ++ +W ++++ C L SI
Sbjct: 2185 VICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIV 2244
Query: 422 SMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDC 481
+ E EF+ + + WIGLND ++ +F WSDG + F +W P +P+NF + EDC
Sbjct: 2245 TPEEQEFVNNNAQ---DYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDC 2301
Query: 482 VT-IWGPEGRWNDSPCNQSLPSICKK 506
V IW +G WND PCN LP CKK
Sbjct: 2302 VVMIWHEKGEWNDVPCNYHLPFTCKK 2327
Score = 99.5 bits (244), Expect = 3e-19
Identities = 57/172 (33%), Positives = 82/172 (47%), Gaps = 12/172 (6%)
Query: 200 GCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSW 259
G + +GH+ C Y + C I CE W+K Q CY+ +F +W
Sbjct: 2174 GAGTCKETEGHVICLCPPGYTGEH----CNIDQEVCEEGWNKYQ--GHCYR-HFPDRETW 2226
Query: 260 REAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKY 319
+A C +Q + L SI EQ ++N Y WIGLND G ++WSD P+++
Sbjct: 2227 VDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHPMQF 2283
Query: 320 LNWESDQPDN--PSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEP 369
NW +QPDN + E+C V+ G W + C+ LP+ CKK A EP
Sbjct: 2284 ENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEP 2335
Score = 80.0 bits (194), Expect = 2e-13
Identities = 50/160 (31%), Positives = 76/160 (47%), Gaps = 14/160 (8%)
Query: 801 DTQLDWICKIPRG-TDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAE 859
+T+ IC P G T D W ++Q Y+ F TW A+R C Q+
Sbjct: 2180 ETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSH 2239
Query: 860 LTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR 919
L+S+ + E +F+++N Q + WIGL+ +G FRW+DG + F +W P +P
Sbjct: 2240 LSSIVTPEEQEFVNNNAQDYQ-------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPD 2292
Query: 920 ---PVGKDKKCVYMT-ASREDWGDQRCLTALPYICKRSNV 955
G+D CV M + +W D C LP+ CK+ V
Sbjct: 2293 NFFAAGED--CVVMIWHEKGEWNDVPCNYHLPFTCKKGTV 2330
Score = 66.0 bits (158), Expect = 3e-09
Identities = 46/180 (25%), Positives = 74/180 (40%), Gaps = 31/180 (17%)
Query: 934 REDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQS 993
+E G CL Y + N+ +E C W ++ C++
Sbjct: 2179 KETEGHVICLCPPGYTGEHCNIDQEV------------CEEGWNKYQGHCYR----HFPD 2222
Query: 994 RVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLH--ASQRDFQWVEQE 1051
R W +A+ C +Q++ L +I P EQ F+ + + WIGL+ + DF+W +
Sbjct: 2223 RETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGH 2279
Query: 1052 PLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGT 1111
P+ + NW P +P A C V++ H G W+D C F C+KGT
Sbjct: 2280 PMQFENWRPNQPDNFFAAGE-----DCVVMIW----HEKGEWNDVPCNYHL-PFTCKKGT 2329
Score = 59.3 bits (141), Expect = 3e-07
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 25/144 (17%)
Query: 669 CPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLN 728
C +GW + +CY+ F D+++WV A+ C+E + L S+ + EE+ FV N
Sbjct: 2205 CEEGW--NKYQGHCYRHFP-----DRETWVDAERRCREQQSHLSSIVTPEEQEFVNN--- 2254
Query: 729 KIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--CA 786
+ Q + WIGLN R G +RWSDG + N+ ++ D+ G C
Sbjct: 2255 ----------NAQDYQWIGLNDRTIEG--DFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 2302
Query: 787 VLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ L + CK
Sbjct: 2303 VMIWHEKGEWNDVPCNYHLPFTCK 2326
Score = 58.6 bits (139), Expect = 5e-07
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 9/139 (6%)
Query: 521 CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYF 580
C +GW + CY D+ T+ +A R C + S L +I EQ FV+ N +Y
Sbjct: 2205 CEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVN----NNAQDYQ 2260
Query: 581 WTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG--YSRGGCVALATGSAMGLWEVKNCTSF 638
W L D G F W G + + +W +QP ++ G + G W C ++
Sbjct: 2261 WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPC-NY 2319
Query: 639 RARYICRQSLGTPVTPELP 657
+ C++ GT E P
Sbjct: 2320 HLPFTCKK--GTVACGEPP 2336
Score = 51.2 bits (120), Expect = 9e-05
Identities = 36/145 (24%), Positives = 54/145 (36%), Gaps = 9/145 (6%)
Query: 1251 PPRRISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEME 1310
PP H + Q + + W ++ HCY H +A +RC+ + SI+ E
Sbjct: 2190 PPGYTGEHCNIDQEVCEEGWNKYQGHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEE 2248
Query: 1311 NVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC- 1369
FV + Q Y+ W+G+N G W D + + NW P + C
Sbjct: 2249 QEFVNNNAQDYQ------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 2302
Query: 1370 YWIQSNSGLWRPGACTNITMGVVCK 1394
I G W C N + CK
Sbjct: 2303 VMIWHEKGEWNDVPC-NYHLPFTCK 2326
Score = 34.8 bits (78), Expect = 7.5
Identities = 17/69 (24%), Positives = 28/69 (39%), Gaps = 3/69 (4%)
Query: 1146 WHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLN 1205
W DA C + L+ + P Q F+ A+ + WIGL + W P+
Sbjct: 2226 WVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHPMQ 2282
Query: 1206 YVGWQDGEP 1214
+ W+ +P
Sbjct: 2283 FENWRPNQP 2291
>gb|AAA35726.1| (J05062) proteoglycan core protein [Homo sapiens]
Length = 480
Score = 117 bits (291), Expect = 8e-25
Identities = 83/266 (31%), Positives = 121/266 (45%), Gaps = 29/266 (10%)
Query: 267 EQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLK-YLNWESD 325
E G + T ++T I+G L+G++S L + ++ W P + +L ES
Sbjct: 130 EAPGLASATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESS 189
Query: 326 QPDNPSEENCGVIRTES--------SGGWQNRDCSIALPYV--CKKKP--NATAEPT--- 370
EE V S S W+ S A C ++P T + T
Sbjct: 190 SLLYSGEETHTVETATSPTDASIPASPEWKRESESTAAAPARSCAEEPCGAGTCKETEGH 249
Query: 371 -----PPD---RWANVKVE-CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIH 421
PP N+ E CE W +QGHCYR ++ +W ++++ C L SI
Sbjct: 250 VICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIV 309
Query: 422 SMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDC 481
+ E EF+ + + WIGLND ++ +F WSDG + F +W P +P+NF + EDC
Sbjct: 310 TPEEQEFVNNNAQ---DYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDC 366
Query: 482 VT-IWGPEGRWNDSPCNQSLPSICKK 506
V IW +G WND PCN LP CKK
Sbjct: 367 VVMIWHEKGEWNDVPCNYHLPFTCKK 392
Score = 99.5 bits (244), Expect = 3e-19
Identities = 57/172 (33%), Positives = 82/172 (47%), Gaps = 12/172 (6%)
Query: 200 GCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSW 259
G + +GH+ C Y + C I CE W+K Q CY+ +F +W
Sbjct: 239 GAGTCKETEGHVICLCPPGYTGEH----CNIDQEVCEEGWNKYQ--GHCYR-HFPDRETW 291
Query: 260 REAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKY 319
+A C +Q + L SI EQ ++N Y WIGLND G ++WSD P+++
Sbjct: 292 VDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHPMQF 348
Query: 320 LNWESDQPDN--PSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEP 369
NW +QPDN + E+C V+ G W + C+ LP+ CKK A EP
Sbjct: 349 ENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEP 400
Score = 80.0 bits (194), Expect = 2e-13
Identities = 50/160 (31%), Positives = 76/160 (47%), Gaps = 14/160 (8%)
Query: 801 DTQLDWICKIPRG-TDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAE 859
+T+ IC P G T D W ++Q Y+ F TW A+R C Q+
Sbjct: 245 ETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSH 304
Query: 860 LTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR 919
L+S+ + E +F+++N Q + WIGL+ +G FRW+DG + F +W P +P
Sbjct: 305 LSSIVTPEEQEFVNNNAQDYQ-------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPD 357
Query: 920 ---PVGKDKKCVYMT-ASREDWGDQRCLTALPYICKRSNV 955
G+D CV M + +W D C LP+ CK+ V
Sbjct: 358 NFFAAGED--CVVMIWHEKGEWNDVPCNYHLPFTCKKGTV 395
Score = 66.0 bits (158), Expect = 3e-09
Identities = 46/180 (25%), Positives = 74/180 (40%), Gaps = 31/180 (17%)
Query: 934 REDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQS 993
+E G CL Y + N+ +E C W ++ C++
Sbjct: 244 KETEGHVICLCPPGYTGEHCNIDQEV------------CEEGWNKYQGHCYR----HFPD 287
Query: 994 RVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLH--ASQRDFQWVEQE 1051
R W +A+ C +Q++ L +I P EQ F+ + + WIGL+ + DF+W +
Sbjct: 288 RETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGH 344
Query: 1052 PLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGT 1111
P+ + NW P +P A C V++ H G W+D C F C+KGT
Sbjct: 345 PMQFENWRPNQPDNFFAAGE-----DCVVMIW----HEKGEWNDVPCNYHL-PFTCKKGT 394
Score = 59.3 bits (141), Expect = 3e-07
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 25/144 (17%)
Query: 669 CPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLN 728
C +GW + +CY+ F D+++WV A+ C+E + L S+ + EE+ FV N
Sbjct: 270 CEEGW--NKYQGHCYRHFP-----DRETWVDAERRCREQQSHLSSIVTPEEQEFVNN--- 319
Query: 729 KIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--CA 786
+ Q + WIGLN R G +RWSDG + N+ ++ D+ G C
Sbjct: 320 ----------NAQDYQWIGLNDRTIEG--DFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 367
Query: 787 VLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ L + CK
Sbjct: 368 VMIWHEKGEWNDVPCNYHLPFTCK 391
Score = 58.6 bits (139), Expect = 5e-07
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 9/139 (6%)
Query: 521 CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYF 580
C +GW + CY D+ T+ +A R C + S L +I EQ FV+ N +Y
Sbjct: 270 CEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVN----NNAQDYQ 325
Query: 581 WTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG--YSRGGCVALATGSAMGLWEVKNCTSF 638
W L D G F W G + + +W +QP ++ G + G W C ++
Sbjct: 326 WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPC-NY 384
Query: 639 RARYICRQSLGTPVTPELP 657
+ C++ GT E P
Sbjct: 385 HLPFTCKK--GTVACGEPP 401
Score = 51.2 bits (120), Expect = 9e-05
Identities = 36/145 (24%), Positives = 54/145 (36%), Gaps = 9/145 (6%)
Query: 1251 PPRRISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEME 1310
PP H + Q + + W ++ HCY H +A +RC+ + SI+ E
Sbjct: 255 PPGYTGEHCNIDQEVCEEGWNKYQGHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEE 313
Query: 1311 NVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC- 1369
FV + Q Y+ W+G+N G W D + + NW P + C
Sbjct: 314 QEFVNNNAQDYQ------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 367
Query: 1370 YWIQSNSGLWRPGACTNITMGVVCK 1394
I G W C N + CK
Sbjct: 368 VMIWHEKGEWNDVPC-NYHLPFTCK 391
Score = 34.8 bits (78), Expect = 7.5
Identities = 17/69 (24%), Positives = 28/69 (39%), Gaps = 3/69 (4%)
Query: 1146 WHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLN 1205
W DA C + L+ + P Q F+ A+ + WIGL + W P+
Sbjct: 291 WVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHPMQ 347
Query: 1206 YVGWQDGEP 1214
+ W+ +P
Sbjct: 348 FENWRPNQP 356
>gb|AAA48719.1| (J04028) proteoglycan core protein [Gallus gallus]
Length = 216
Score = 116 bits (288), Expect = 2e-24
Identities = 53/126 (42%), Positives = 72/126 (57%), Gaps = 4/126 (3%)
Query: 382 CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELW 441
CE W FQGHCYR E+ +W +++ C L SI + E EF+ + + W
Sbjct: 4 CEEGWIKFQGHCYRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQ---DYQW 60
Query: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSL 500
IGL+D ++ +F WSDG + F +W P +P+NF + EDCV IW +G WND PCN L
Sbjct: 61 IGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFSAGEDCVVMIWHEQGEWNDVPCNYHL 120
Query: 501 PSICKK 506
P CKK
Sbjct: 121 PFTCKK 126
Score = 86.6 bits (211), Expect = 2e-15
Identities = 56/193 (29%), Positives = 91/193 (47%), Gaps = 24/193 (12%)
Query: 234 DCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYS 293
+CE W K Q CY+ +F+ +W +A + C + A L SI EQ ++N Y
Sbjct: 3 NCEEGWIKFQ--GHCYR-HFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQDYQ 59
Query: 294 STLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTESSGGWQNRDC 351
WIGL+D ++WSD L++ NW +QPDN + E+C V+ G W + C
Sbjct: 60 ---WIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFSAGEDCVVMIWHEQGEWNDVPC 116
Query: 352 SIALPYVCKKKPNATAEP----------TPPDRW---ANVKVECEPSWQPFQGHCYRLQA 398
+ LP+ CKK A +P DR+ + V+ +C+ + Q H ++
Sbjct: 117 NYHLPFTCKKGTVACGDPPVVENARTFGRKKDRYEINSLVRYQCDHGY--IQRHVPTIRC 174
Query: 399 EKRS-WQESKKAC 410
+ W+E + +C
Sbjct: 175 QPNGHWEEPRISC 187
Score = 79.6 bits (193), Expect = 2e-13
Identities = 43/131 (32%), Positives = 65/131 (48%), Gaps = 13/131 (9%)
Query: 829 WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWW 888
W++FQ Y+ FE TW A+ C QA L+S+ + E +F++ + Q + W
Sbjct: 8 WIKFQGHCYRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQDYQ-------W 60
Query: 889 IGLHTSESDGRFRWTDGSIINFISWAPGKPR---PVGKDKKCVYMTASRE-DWGDQRCLT 944
IGL + FRW+DG + F +W P +P G+D CV M + +W D C
Sbjct: 61 IGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFSAGED--CVVMIWHEQGEWNDVPCNY 118
Query: 945 ALPYICKRSNV 955
LP+ CK+ V
Sbjct: 119 HLPFTCKKGTV 129
Score = 71.0 bits (171), Expect = 9e-11
Identities = 43/145 (29%), Positives = 64/145 (43%), Gaps = 19/145 (13%)
Query: 969 LGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLP 1028
L C WI+F C++ + R W +A+ C + +A L +I P EQ F+ +
Sbjct: 1 LANCEEGWIKFQGHCYR----HFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQ 56
Query: 1029 NVTFDLWIGL--HASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPS 1086
+ WIGL A + DF+W + L + NW P +P A C V++
Sbjct: 57 DYQ---WIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFSAGE-----DCVVMIW--- 105
Query: 1087 AHFTGRWDDRSCTEETHGFICQKGT 1111
H G W+D C F C+KGT
Sbjct: 106 -HEQGEWNDVPCNYHL-PFTCKKGT 128
Score = 55.8 bits (132), Expect = 3e-06
Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 25/145 (17%)
Query: 668 SCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANML 727
+C +GW +CY+ F +++++W+ A+ C+E A L S+ + EE+ FV +
Sbjct: 3 NCEEGWIKFQG--HCYRHF-----EERETWMDAESRCREHQAHLSSIITPEEQEFVNS-- 53
Query: 728 NKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--C 785
H Q + WIGL+ R +RWSDG + N+ ++ D+ G C
Sbjct: 54 -----------HAQDYQWIGLSDRAVE--NDFRWSDGHSLQFENWRPNQPDNFFSAGEDC 100
Query: 786 AVLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ L + CK
Sbjct: 101 VVMIWHEQGEWNDVPCNYHLPFTCK 125
Score = 55.4 bits (131), Expect = 5e-06
Identities = 33/128 (25%), Positives = 54/128 (41%), Gaps = 7/128 (5%)
Query: 521 CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYF 580
C +GW CY E++ T+ +A C +H + L +I EQ FV+S +Y
Sbjct: 4 CEEGWIKFQGHCYRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNS----HAQDYQ 59
Query: 581 WTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG--YSRGGCVALATGSAMGLWEVKNCTSF 638
W L D F W G + + +W +QP +S G + G W C ++
Sbjct: 60 WIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFSAGEDCVVMIWHEQGEWNDVPC-NY 118
Query: 639 RARYICRQ 646
+ C++
Sbjct: 119 HLPFTCKK 126
Score = 51.2 bits (120), Expect = 9e-05
Identities = 34/129 (26%), Positives = 49/129 (37%), Gaps = 9/129 (6%)
Query: 1267 DSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSR 1326
+ WI F+ HCY H E +A RC+ + SI+ E FV H Q Y+
Sbjct: 5 EEGWIKFQGHCYR-HFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQDYQ---- 59
Query: 1327 GAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YWIQSNSGLWRPGACT 1385
W+G++ W D ++ + NW P + C I G W C
Sbjct: 60 --WIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFSAGEDCVVMIWHEQGEWNDVPC- 116
Query: 1386 NITMGVVCK 1394
N + CK
Sbjct: 117 NYHLPFTCK 125
Score = 39.9 bits (91), Expect = 0.22
Identities = 20/78 (25%), Positives = 33/78 (41%), Gaps = 3/78 (3%)
Query: 1137 FRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRY 1196
+R ++ W DA C H A L+ + P Q F+ A+ + WIGL+ +
Sbjct: 16 YRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQDYQ---WIGLSDRAVENDF 72
Query: 1197 SWVSEEPLNYVGWQDGEP 1214
W L + W+ +P
Sbjct: 73 RWSDGHSLQFENWRPNQP 90
>gb|AAC60053.1| (U78555) chondroitin sulfate proteoglycan core protein [Gallus
gallus]
Length = 2109
Score = 115 bits (285), Expect = 4e-24
Identities = 53/126 (42%), Positives = 72/126 (57%), Gaps = 4/126 (3%)
Query: 382 CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELW 441
CE W FQGHCYR E+ +W +++ C L SI + E EF+ + + W
Sbjct: 1897 CEEGWIKFQGHCYRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQ---DYQW 1953
Query: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSL 500
IGL+D ++ +F WSDG + F +W P +P+NF + EDCV IW +G WND PCN L
Sbjct: 1954 IGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGEDCVVMIWHEQGEWNDVPCNYHL 2013
Query: 501 PSICKK 506
P CKK
Sbjct: 2014 PFTCKK 2019
Score = 90.9 bits (222), Expect = 1e-16
Identities = 62/214 (28%), Positives = 97/214 (44%), Gaps = 28/214 (13%)
Query: 213 CATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGAD 272
C YG D C I +CE W K Q CY+ +F+ +W +A + C + A
Sbjct: 1879 CLCLPSYGGD----LCEIDLANCEEGWIKFQ--GHCYR-HFEERETWMDAESRCREHQAH 1931
Query: 273 LLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--P 330
L SI EQ ++N Y WIGL+D ++WSD L++ NW +QPDN
Sbjct: 1932 LSSIITPEEQEFVNSHAQDYQ---WIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFF 1988
Query: 331 SEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEP----------TPPDRW---AN 377
+ E+C V+ G W + C+ LP+ CKK A +P DR+ +
Sbjct: 1989 AGEDCVVMIWHEQGEWNDVPCNYHLPFTCKKGTVACGDPPVVENARTFGRKKDRYEINSL 2048
Query: 378 VKVECEPSWQPFQGHCYRLQAEKRS-WQESKKAC 410
V+ +C+ + Q H ++ + W+E + +C
Sbjct: 2049 VRYQCDHGY--IQRHVPTIRCQPNGHWEEPRISC 2080
Score = 79.2 bits (192), Expect = 3e-13
Identities = 43/131 (32%), Positives = 65/131 (48%), Gaps = 13/131 (9%)
Query: 829 WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWW 888
W++FQ Y+ FE TW A+ C QA L+S+ + E +F++ + Q + W
Sbjct: 1901 WIKFQGHCYRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQDYQ-------W 1953
Query: 889 IGLHTSESDGRFRWTDGSIINFISWAPGKPRP---VGKDKKCVYMTASRE-DWGDQRCLT 944
IGL + FRW+DG + F +W P +P G+D CV M + +W D C
Sbjct: 1954 IGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGED--CVVMIWHEQGEWNDVPCNY 2011
Query: 945 ALPYICKRSNV 955
LP+ CK+ V
Sbjct: 2012 HLPFTCKKGTV 2022
Score = 71.0 bits (171), Expect = 9e-11
Identities = 45/151 (29%), Positives = 66/151 (42%), Gaps = 19/151 (12%)
Query: 963 DLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAF 1022
DL L C WI+F C++ + R W +A+ C + +A L +I P EQ F
Sbjct: 1888 DLCEIDLANCEEGWIKFQGHCYR----HFEERETWMDAESRCREHQAHLSSIITPEEQEF 1943
Query: 1023 ITASLPNVTFDLWIGL--HASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAV 1080
+ + + WIGL A + DF+W + L + NW P +P A C V
Sbjct: 1944 VNSHAQDYQ---WIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGE-----DCVV 1995
Query: 1081 VLHSPSAHFTGRWDDRSCTEETHGFICQKGT 1111
++ H G W+D C F C+KGT
Sbjct: 1996 MIW----HEQGEWNDVPCNYHL-PFTCKKGT 2021
Score = 56.6 bits (134), Expect = 2e-06
Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 25/145 (17%)
Query: 668 SCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANML 727
+C +GW +CY+ F +++++W+ A+ C+E A L S+ + EE+ FV +
Sbjct: 1896 NCEEGWIKFQG--HCYRHF-----EERETWMDAESRCREHQAHLSSIITPEEQEFVNS-- 1946
Query: 728 NKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--C 785
H Q + WIGL+ R +RWSDG + N+ ++ D+ G C
Sbjct: 1947 -----------HAQDYQWIGLSDRAVE--NDFRWSDGHSLQFENWRPNQPDNFFFAGEDC 1993
Query: 786 AVLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ L + CK
Sbjct: 1994 VVMIWHEQGEWNDVPCNYHLPFTCK 2018
Score = 53.5 bits (126), Expect = 2e-05
Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 9/129 (6%)
Query: 521 CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYF 580
C +GW CY E++ T+ +A C +H + L +I EQ FV+S +Y
Sbjct: 1897 CEEGWIKFQGHCYRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNS----HAQDYQ 1952
Query: 581 WTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG---YSRGGCVALATGSAMGLWEVKNCTS 637
W L D F W G + + +W +QP ++ CV + G W C +
Sbjct: 1953 WIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGEDCVVM-IWHEQGEWNDVPC-N 2010
Query: 638 FRARYICRQ 646
+ + C++
Sbjct: 2011 YHLPFTCKK 2019
Score = 52.7 bits (124), Expect = 3e-05
Identities = 40/143 (27%), Positives = 55/143 (37%), Gaps = 12/143 (8%)
Query: 1256 SYHGS-CPQGLA--DSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENV 1312
SY G C LA + WI F+ HCY H E +A RC+ + SI+ E
Sbjct: 1884 SYGGDLCEIDLANCEEGWIKFQGHCYR-HFEERETWMDAESRCREHQAHLSSIITPEEQE 1942
Query: 1313 FVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YW 1371
FV H Q Y+ W+G++ W D ++ + NW P + C
Sbjct: 1943 FVNSHAQDYQ------WIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGEDCVVM 1996
Query: 1372 IQSNSGLWRPGACTNITMGVVCK 1394
I G W C N + CK
Sbjct: 1997 IWHEQGEWNDVPC-NYHLPFTCK 2018
Score = 41.4 bits (95), Expect = 0.076
Identities = 32/127 (25%), Positives = 47/127 (36%), Gaps = 19/127 (14%)
Query: 1137 FRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRY 1196
+R ++ W DA C H A L+ + P Q F+ A+ + WIGL+ +
Sbjct: 1909 YRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQDYQ---WIGLSDRAVENDF 1965
Query: 1197 SWVSEEPLNYVGWQDGEPQQPGGCTYVDVD---------GAWRTTSCDTKLQGAVC---G 1244
W L + W+ P QP + D G W C+ L C
Sbjct: 1966 RWSDGHSLQFENWR---PNQPDNFFFAGEDCVVMIWHEQGEWNDVPCNYHLP-FTCKKGT 2021
Query: 1245 VSSGPPP 1251
V+ G PP
Sbjct: 2022 VACGDPP 2028
>emb|CAA42701.1| (X60107) cartilage aggregating proteoglycan [Sus scrofa]
Length = 339
Score = 115 bits (285), Expect = 4e-24
Identities = 77/242 (31%), Positives = 113/242 (45%), Gaps = 20/242 (8%)
Query: 267 EQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKY-LNWESD 325
E G L + ++T ++G L+G++S L + ++ W P + L ES
Sbjct: 28 EASGLPLATPVSSGDRTEVSGDLSGHTSGLEVAISTAIPEYAWTQQTQRPAEAPLEIESS 87
Query: 326 QPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPS 385
P + EE + + SI P + AT A+ K+ CE
Sbjct: 88 SPVHSGEE-----MPTAKPATSQTEASIPTPPGQTDESEATT--------ADQKL-CENG 133
Query: 386 WQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIGLN 445
Q QGHCYR ++ +W +++ C + L SI + E EF+ + E WIGLN
Sbjct: 134 SQ-IQGHCYRHFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQ---EYQWIGLN 189
Query: 446 DLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSLPSIC 504
D ++ +F WSDG + F W P +P+NF + EDCV IW +G WND PCN LP C
Sbjct: 190 DKTIEGDFRWSDGHSLQFESWSPNQPDNFFATGEDCVVMIWHEKGEWNDVPCNYQLPFTC 249
Query: 505 KK 506
KK
Sbjct: 250 KK 251
Score = 86.6 bits (211), Expect = 2e-15
Identities = 45/129 (34%), Positives = 67/129 (51%), Gaps = 6/129 (4%)
Query: 243 QLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLND 302
Q+ CY+ +F +W +A + C +Q + L SI EQ ++N Y WIGLND
Sbjct: 135 QIQGHCYR-HFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQEYQ---WIGLND 190
Query: 303 LDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTESSGGWQNRDCSIALPYVCK 360
G ++WSD L++ +W +QPDN + E+C V+ G W + C+ LP+ CK
Sbjct: 191 KTIEGDFRWSDGHSLQFESWSPNQPDNFFATGEDCVVMIWHEKGEWNDVPCNYQLPFTCK 250
Query: 361 KKPNATAEP 369
K A EP
Sbjct: 251 KGTVACGEP 259
Score = 79.2 bits (192), Expect = 3e-13
Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 24/182 (13%)
Query: 837 YKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSES 896
Y+ F +TW A+ C Q+ L+S+ + E +F+++N Q++ WIGL+
Sbjct: 141 YRHFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQEYQ-------WIGLNDKTI 193
Query: 897 DGRFRWTDGSIINFISWAPGKPR---PVGKDKKCVYMT-ASREDWGDQRCLTALPYICKR 952
+G FRW+DG + F SW+P +P G+D CV M + +W D C LP+ CK+
Sbjct: 194 EGDFRWSDGHSLQFESWSPNQPDNFFATGED--CVVMIWHEKGEWNDVPCNYQLPFTCKK 251
Query: 953 SNVTKETQPPDLPTTALGGCPSDWIQFLN----KCFQ--VQGQEPQSRVK----WSEAQF 1002
V +PP + + G D + + +C + VQ P R + W E +
Sbjct: 252 GTVAC-GEPPVVEHARIFGKKKDRYEINSLVRYQCTEGFVQRHVPTIRCQPSGHWEEPRI 310
Query: 1003 SC 1004
+C
Sbjct: 311 TC 312
Score = 58.2 bits (138), Expect = 7e-07
Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 18/132 (13%)
Query: 985 QVQG---QEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLHAS 1041
Q+QG + R W +A+ C +Q++ L +I P EQ F+ + WIGL+
Sbjct: 135 QIQGHCYRHFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQEYQ---WIGLNDK 191
Query: 1042 --QRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCT 1099
+ DF+W + L + +W+P +P C V++ H G W+D C
Sbjct: 192 TIEGDFRWSDGHSLQFESWSPNQPDNFFATGE-----DCVVMIW----HEKGEWNDVPCN 242
Query: 1100 EETHGFICQKGT 1111
+ F C+KGT
Sbjct: 243 YQL-PFTCKKGT 253
Score = 58.2 bits (138), Expect = 7e-07
Identities = 45/170 (26%), Positives = 74/170 (43%), Gaps = 31/170 (18%)
Query: 651 PVTPELPGPDPTPSLTGSCPQGWASDTKL--------RYCYKVFSSERLQDKKSWVQAQG 702
P T + PTP + +D KL +CY+ F D+ +WV A+
Sbjct: 101 PATSQTEASIPTPPGQTDESEATTADQKLCENGSQIQGHCYRHFP-----DRATWVDAES 155
Query: 703 ACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWS 762
C++ + L S+ + EE+ FV N + Q + WIGLN + G +RWS
Sbjct: 156 QCRKQQSHLSSIVTPEEQEFVNN-------------NAQEYQWIGLNDKTIEG--DFRWS 200
Query: 763 DGVGFSYHNFDRSRHDDDDIRG--CAVLDLASL-QWVAMQCDTQLDWICK 809
DG + ++ ++ D+ G C V+ +W + C+ QL + CK
Sbjct: 201 DGHSLQFESWSPNQPDNFFATGEDCVVMIWHEKGEWNDVPCNYQLPFTCK 250
Score = 48.8 bits (114), Expect = 4e-04
Identities = 42/173 (24%), Positives = 67/173 (38%), Gaps = 27/173 (15%)
Query: 487 PEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEAR 546
P G+ ++S + +C+ Q+ QG CY D+ T+ +A
Sbjct: 113 PPGQTDESEATTADQKLCENGSQI-QG-----------------HCYRHFPDRATWVDAE 154
Query: 547 RLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDEVMYTHW 606
C S L +I EQ FV+ N EY W L D G F W G + + W
Sbjct: 155 SQCRKQQSHLSSIVTPEEQEFVN----NNAQEYQWIGLNDKTIEGDFRWSDGHSLQFESW 210
Query: 607 NRDQPG--YSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELP 657
+ +QP ++ G + G W C +++ + C++ GT E P
Sbjct: 211 SPNQPDNFFATGEDCVVMIWHEKGEWNDVPC-NYQLPFTCKK--GTVACGEPP 260
Score = 40.6 bits (93), Expect = 0.13
Identities = 29/120 (24%), Positives = 45/120 (37%), Gaps = 9/120 (7%)
Query: 1276 HCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFN 1335
HCY H +A +C++ + SI+ E FV + Q Y+ W+G+N
Sbjct: 139 HCYR-HFPDRATWVDAESQCRKQQSHLSSIVTPEEQEFVNNNAQEYQ------WIGLNDK 191
Query: 1336 PKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YWIQSNSGLWRPGACTNITMGVVCK 1394
G W D ++ + +W P + C I G W C N + CK
Sbjct: 192 TIEGDFRWSDGHSLQFESWSPNQPDNFFATGEDCVVMIWHEKGEWNDVPC-NYQLPFTCK 250
>pir||S39796 aggrecan precursor - chicken
Length = 2071
Score = 115 bits (285), Expect = 4e-24
Identities = 53/126 (42%), Positives = 72/126 (57%), Gaps = 4/126 (3%)
Query: 382 CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELW 441
CE W FQGHCYR E+ +W +++ C L SI + E EF+ + + W
Sbjct: 1859 CEEGWIKFQGHCYRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQ---DYQW 1915
Query: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSL 500
IGL+D ++ +F WSDG + F +W P +P+NF + EDCV IW +G WND PCN L
Sbjct: 1916 IGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGEDCVVMIWHEQGEWNDVPCNYHL 1975
Query: 501 PSICKK 506
P CKK
Sbjct: 1976 PFTCKK 1981
Score = 85.4 bits (208), Expect = 4e-15
Identities = 56/193 (29%), Positives = 91/193 (47%), Gaps = 24/193 (12%)
Query: 234 DCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYS 293
+CE W K Q CY+ +F+ +W +A + C + A L SI EQ ++N Y
Sbjct: 1858 NCEEGWIKFQ--GHCYR-HFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQDYQ 1914
Query: 294 STLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTESSGGWQNRDC 351
WIGL+D ++WSD L++ NW +QPDN + E+C V+ G W + C
Sbjct: 1915 ---WIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGEDCVVMIWHEQGEWNDVPC 1971
Query: 352 SIALPYVCKKKPNATAEP----------TPPDRW---ANVKVECEPSWQPFQGHCYRLQA 398
+ LP+ CKK A +P DR+ + V+ +C+ + Q H ++
Sbjct: 1972 NYHLPFTCKKGTVACGDPPVVENARTFGRKKDRYEINSLVRYQCDHGY--IQRHVPTIRC 2029
Query: 399 EKRS-WQESKKAC 410
+ W+E + +C
Sbjct: 2030 QPNGHWEEPRISC 2042
Score = 79.2 bits (192), Expect = 3e-13
Identities = 43/131 (32%), Positives = 65/131 (48%), Gaps = 13/131 (9%)
Query: 829 WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWW 888
W++FQ Y+ FE TW A+ C QA L+S+ + E +F++ + Q + W
Sbjct: 1863 WIKFQGHCYRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQDYQ-------W 1915
Query: 889 IGLHTSESDGRFRWTDGSIINFISWAPGKPRP---VGKDKKCVYMTASRE-DWGDQRCLT 944
IGL + FRW+DG + F +W P +P G+D CV M + +W D C
Sbjct: 1916 IGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGED--CVVMIWHEQGEWNDVPCNY 1973
Query: 945 ALPYICKRSNV 955
LP+ CK+ V
Sbjct: 1974 HLPFTCKKGTV 1984
Score = 71.4 bits (172), Expect = 7e-11
Identities = 46/150 (30%), Positives = 67/150 (44%), Gaps = 20/150 (13%)
Query: 965 PTTA-LGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFI 1023
PTT L C WI+F C++ + R W +A+ C + +A L +I P EQ F+
Sbjct: 1851 PTTEDLANCEEGWIKFQGHCYR----HFEERETWMDAESRCREHQAHLSSIITPEEQEFV 1906
Query: 1024 TASLPNVTFDLWIGL--HASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVV 1081
+ + WIGL A + DF+W + L + NW P +P A C V+
Sbjct: 1907 NSHAQDYQ---WIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGE-----DCVVM 1958
Query: 1082 LHSPSAHFTGRWDDRSCTEETHGFICQKGT 1111
+ H G W+D C F C+KGT
Sbjct: 1959 IW----HEQGEWNDVPCNYHL-PFTCKKGT 1983
Score = 58.9 bits (140), Expect = 4e-07
Identities = 41/152 (26%), Positives = 70/152 (45%), Gaps = 25/152 (16%)
Query: 661 PTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEE 720
PT +C +GW +CY+ F +++++W+ A+ C+E A L S+ + EE+
Sbjct: 1851 PTTEDLANCEEGWIKFQG--HCYRHF-----EERETWMDAESRCREHQAHLSSIITPEEQ 1903
Query: 721 HFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDD 780
FV + H Q + WIGL+ R +RWSDG + N+ ++ D+
Sbjct: 1904 EFVNS-------------HAQDYQWIGLSDRAVE--NDFRWSDGHSLQFENWRPNQPDNF 1948
Query: 781 DIRG--CAVLDLASL-QWVAMQCDTQLDWICK 809
G C V+ +W + C+ L + CK
Sbjct: 1949 FFAGEDCVVMIWHEQGEWNDVPCNYHLPFTCK 1980
Score = 53.9 bits (127), Expect = 1e-05
Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 9/134 (6%)
Query: 516 EEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNW 575
E+ C +GW CY E++ T+ +A C +H + L +I EQ FV+S
Sbjct: 1854 EDLANCEEGWIKFQGHCYRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNS----H 1909
Query: 576 EGEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG---YSRGGCVALATGSAMGLWEV 632
+Y W L D F W G + + +W +QP ++ CV + G W
Sbjct: 1910 AQDYQWIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGEDCVVM-IWHEQGEWND 1968
Query: 633 KNCTSFRARYICRQ 646
C ++ + C++
Sbjct: 1969 VPC-NYHLPFTCKK 1981
Score = 51.9 bits (122), Expect = 5e-05
Identities = 34/129 (26%), Positives = 49/129 (37%), Gaps = 9/129 (6%)
Query: 1267 DSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSR 1326
+ WI F+ HCY H E +A RC+ + SI+ E FV H Q Y+
Sbjct: 1860 EEGWIKFQGHCYR-HFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQDYQ---- 1914
Query: 1327 GAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YWIQSNSGLWRPGACT 1385
W+G++ W D ++ + NW P + C I G W C
Sbjct: 1915 --WIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGEDCVVMIWHEQGEWNDVPC- 1971
Query: 1386 NITMGVVCK 1394
N + CK
Sbjct: 1972 NYHLPFTCK 1980
Score = 46.5 bits (108), Expect = 0.002
Identities = 52/202 (25%), Positives = 75/202 (36%), Gaps = 31/202 (15%)
Query: 1062 EPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAA 1121
EPS +PA SG + T A VL +P T T H Q+ D +L P+
Sbjct: 1808 EPS--TPAASGQE-TETAAVLDNPHLPATA-------TAALHP-ASQEAVD-ALGPTTED 1855
Query: 1122 LPPAPGTELSYLNGTFRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRT 1181
L + + +R ++ W DA C H A L+ + P Q F+ A+ +
Sbjct: 1856 LANCEEGWIKFQGHCYRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQDYQ- 1914
Query: 1182 PLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQPGGCTYVDVD---------GAWRTT 1232
WIGL+ + W L + W+ P QP + D G W
Sbjct: 1915 --WIGLSDRAVENDFRWSDGHSLQFENWR---PNQPDNFFFAGEDCVVMIWHEQGEWNDV 1969
Query: 1233 SCDTKLQGAVC---GVSSGPPP 1251
C+ L C V+ G PP
Sbjct: 1970 PCNYHLP-FTCKKGTVACGDPP 1990
>sp|P07898|PGCA_CHICK AGGRECAN CORE PROTEIN PRECURSOR (CARTILAGE-SPECIFIC PROTEOGLYCAN CORE
PROTEIN) (CSPCP)
pir||I50421 aggrecan precursor - chicken
gb|AAB19128.1| (L21913) chondroitin sulfate proteoglycan core protein [Gallus
gallus]
Length = 2109
Score = 115 bits (285), Expect = 4e-24
Identities = 53/126 (42%), Positives = 72/126 (57%), Gaps = 4/126 (3%)
Query: 382 CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELW 441
CE W FQGHCYR E+ +W +++ C L SI + E EF+ + + W
Sbjct: 1897 CEEGWIKFQGHCYRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQ---DYQW 1953
Query: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSL 500
IGL+D ++ +F WSDG + F +W P +P+NF + EDCV IW +G WND PCN L
Sbjct: 1954 IGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGEDCVVMIWHEQGEWNDVPCNYHL 2013
Query: 501 PSICKK 506
P CKK
Sbjct: 2014 PFTCKK 2019
Score = 90.9 bits (222), Expect = 1e-16
Identities = 62/214 (28%), Positives = 97/214 (44%), Gaps = 28/214 (13%)
Query: 213 CATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGAD 272
C YG D C I +CE W K Q CY+ +F+ +W +A + C + A
Sbjct: 1879 CLCLPSYGGD----LCEIDLANCEEGWIKFQ--GHCYR-HFEERETWMDAESRCREHQAH 1931
Query: 273 LLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--P 330
L SI EQ ++N Y WIGL+D ++WSD L++ NW +QPDN
Sbjct: 1932 LSSIITPEEQEFVNSHAQDYQ---WIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFF 1988
Query: 331 SEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEP----------TPPDRW---AN 377
+ E+C V+ G W + C+ LP+ CKK A +P DR+ +
Sbjct: 1989 AGEDCVVMIWHEQGEWNDVPCNYHLPFTCKKGTVACGDPPVVENARTFGRKKDRYEINSL 2048
Query: 378 VKVECEPSWQPFQGHCYRLQAEKRS-WQESKKAC 410
V+ +C+ + Q H ++ + W+E + +C
Sbjct: 2049 VRYQCDHGY--IQRHVPTIRCQPNGHWEEPRISC 2080
Score = 79.2 bits (192), Expect = 3e-13
Identities = 43/131 (32%), Positives = 65/131 (48%), Gaps = 13/131 (9%)
Query: 829 WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWW 888
W++FQ Y+ FE TW A+ C QA L+S+ + E +F++ + Q + W
Sbjct: 1901 WIKFQGHCYRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQDYQ-------W 1953
Query: 889 IGLHTSESDGRFRWTDGSIINFISWAPGKPRP---VGKDKKCVYMTASRE-DWGDQRCLT 944
IGL + FRW+DG + F +W P +P G+D CV M + +W D C
Sbjct: 1954 IGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGED--CVVMIWHEQGEWNDVPCNY 2011
Query: 945 ALPYICKRSNV 955
LP+ CK+ V
Sbjct: 2012 HLPFTCKKGTV 2022
Score = 71.0 bits (171), Expect = 9e-11
Identities = 45/151 (29%), Positives = 66/151 (42%), Gaps = 19/151 (12%)
Query: 963 DLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAF 1022
DL L C WI+F C++ + R W +A+ C + +A L +I P EQ F
Sbjct: 1888 DLCEIDLANCEEGWIKFQGHCYR----HFEERETWMDAESRCREHQAHLSSIITPEEQEF 1943
Query: 1023 ITASLPNVTFDLWIGL--HASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAV 1080
+ + + WIGL A + DF+W + L + NW P +P A C V
Sbjct: 1944 VNSHAQDYQ---WIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGE-----DCVV 1995
Query: 1081 VLHSPSAHFTGRWDDRSCTEETHGFICQKGT 1111
++ H G W+D C F C+KGT
Sbjct: 1996 MIW----HEQGEWNDVPCNYHL-PFTCKKGT 2021
Score = 56.6 bits (134), Expect = 2e-06
Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 25/145 (17%)
Query: 668 SCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANML 727
+C +GW +CY+ F +++++W+ A+ C+E A L S+ + EE+ FV +
Sbjct: 1896 NCEEGWIKFQG--HCYRHF-----EERETWMDAESRCREHQAHLSSIITPEEQEFVNS-- 1946
Query: 728 NKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--C 785
H Q + WIGL+ R +RWSDG + N+ ++ D+ G C
Sbjct: 1947 -----------HAQDYQWIGLSDRAVE--NDFRWSDGHSLQFENWRPNQPDNFFFAGEDC 1993
Query: 786 AVLDLASL-QWVAMQCDTQLDWICK 809
V+ +W + C+ L + CK
Sbjct: 1994 VVMIWHEQGEWNDVPCNYHLPFTCK 2018
Score = 53.5 bits (126), Expect = 2e-05
Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 9/129 (6%)
Query: 521 CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYF 580
C +GW CY E++ T+ +A C +H + L +I EQ FV+S +Y
Sbjct: 1897 CEEGWIKFQGHCYRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNS----HAQDYQ 1952
Query: 581 WTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG---YSRGGCVALATGSAMGLWEVKNCTS 637
W L D F W G + + +W +QP ++ CV + G W C +
Sbjct: 1953 WIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGEDCVVM-IWHEQGEWNDVPC-N 2010
Query: 638 FRARYICRQ 646
+ + C++
Sbjct: 2011 YHLPFTCKK 2019
Score = 52.7 bits (124), Expect = 3e-05
Identities = 40/143 (27%), Positives = 55/143 (37%), Gaps = 12/143 (8%)
Query: 1256 SYHGS-CPQGLA--DSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENV 1312
SY G C LA + WI F+ HCY H E +A RC+ + SI+ E
Sbjct: 1884 SYGGDLCEIDLANCEEGWIKFQGHCYR-HFEERETWMDAESRCREHQAHLSSIITPEEQE 1942
Query: 1313 FVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC-YW 1371
FV H Q Y+ W+G++ W D ++ + NW P + C
Sbjct: 1943 FVNSHAQDYQ------WIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGEDCVVM 1996
Query: 1372 IQSNSGLWRPGACTNITMGVVCK 1394
I G W C N + CK
Sbjct: 1997 IWHEQGEWNDVPC-NYHLPFTCK 2018
Score = 41.4 bits (95), Expect = 0.076
Identities = 32/127 (25%), Positives = 47/127 (36%), Gaps = 19/127 (14%)
Query: 1137 FRLLQKPLRWHDALLLCESHNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRY 1196
+R ++ W DA C H A L+ + P Q F+ A+ + WIGL+ +
Sbjct: 1909 YRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQDYQ---WIGLSDRAVENDF 1965
Query: 1197 SWVSEEPLNYVGWQDGEPQQPGGCTYVDVD---------GAWRTTSCDTKLQGAVC---G 1244
W L + W+ P QP + D G W C+ L C
Sbjct: 1966 RWSDGHSLQFENWR---PNQPDNFFFAGEDCVVMIWHEQGEWNDVPCNYHLP-FTCKKGT 2021
Query: 1245 VSSGPPP 1251
V+ G PP
Sbjct: 2022 VACGDPP 2028
Database: nr
Posted date: Dec 10, 2000 7:21 PM
Number of letters in database: 188,047,558
Number of sequences in database: 594,795
Lambda K H
0.318 0.135 0.451
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 660533356
Number of Sequences: 594795
Number of extensions: 31721362
Number of successful extensions: 82335
Number of sequences better than 10.0: 923
Number of HSP's better than 10.0 without gapping: 559
Number of HSP's successfully gapped in prelim test: 364
Number of HSP's that attempted gapping in prelim test: 73230
Number of HSP's gapped (non-prelim): 5434
length of query: 1479
length of database: 188,047,558
effective HSP length: 53
effective length of query: 1426
effective length of database: 156,523,423
effective search space: 223202401198
effective search space used: 223202401198
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 77 (34.4 bits)
