Score E
Sequences producing significant alignments: (bits) Value
pir||T47166 hypothetical protein DKFZp762B245.1 - human (fr... 840 0.0
gb|AAC34395.1| (AF056116) unknown [Takifugu rubripes] 740 0.0
ref|NP_062653.1| formin-related gene in leukocytes; lymphoc... 522 e-147
gb|AAF25953.1| (AF215666) formin-like protein [Mus musculus] 498 e-140
ref|NP_005883.1| formin-like; chromosome 17 open reading f... 476 e-133
gb|AAF49761.1| (AE003536) CG6807 gene product [Drosophila m... 371 e-102
gb|AAF60718.1| (AC024798) contains similarity to TR:Q9Z2V7 ... 250 2e-65
dbj|BAA31641.1| (AB014566) KIAA0666 protein [Homo sapiens] 233 4e-60
dbj|BAA20835.1| (AB002379) KIAA0381 [Homo sapiens] 230 2e-59
gb|AAF45601.1| (AE003420) EG:114D9.2 gene product [Drosophi... 206 4e-52
emb|CAA21052.1| (AL031640) /prediction=(method:""genscan"",... 206 4e-52
gb|AAC69221.2| (AF101312) contains similarity to human diap... 180 4e-44
ref|NP_062644.1| diaphanous homolog 3 (Drosophila); diaphan... 179 7e-44
ref|NP_005210.1| diaphanous 1; Diaphanous, Drosophila, homo... 175 1e-42
ref|XP_003754.1| diaphanous 1 [Homo sapiens] 174 2e-42
ref|NP_006720.1| diaphanous 2 isoform 12C; Diaphanous, Dros... 173 5e-42
ref|NP_009293.1| diaphanous 2 isoform 12C; Diaphanous, Dros... 173 5e-42
gb|AAG31306.1|AC079041_8 (AC079041) unknown protein [Arabid... 170 4e-41
ref|NP_031884.1| diaphanous homolog 1 (Drosophila) [Mus mus... 166 4e-40
sp|P48608|DIA_DROME DIAPHANOUS PROTEIN >gi|11359834|pir||T1... 163 4e-39
gb|AAF53922.1| (AE003668) dia gene product [Drosophila mela... 162 6e-39
emb|CAC17664.1| (AL354829) bA218B22.1.1 (novel protein (pre... 156 5e-37
pir||T46476 hypothetical protein DKFZp434C0931.1 - human >g... 150 3e-35
dbj|BAB09942.1| (AB005249) contains similarity to unknown p... 143 3e-33
dbj|BAB09941.1| (AB005249) gene_id:MBK20.23~unknown protein... 142 8e-33
dbj|BAB11455.1| (AB010070) contains similarity to unknown p... 135 1e-30
dbj|BAB11443.1| (AB010070) gene_id:MBK20.9~pir||T17454~simi... 135 1e-30
gb|AAF50614.1| (AE003560) CG8633 gene product [Drosophila m... 133 4e-30
sp|O70566|DIA2_MOUSE DIAPHANOUS PROTEIN HOMOLOG 2 >gi|31719... 129 7e-29
sp|Q05859|FOR4_MOUSE FORMIN 4 (LIMB DEFORMITY PROTEIN) >gi|... 128 2e-28
dbj|BAA96907.1| (AB019228) gb|AAD23008.1~gene_id:MCK7.3~str... 124 2e-27
gb|AAG31020.1|AF099933_1 (AF099933) GluR-delta2 specific in... 120 4e-26
emb|CAC17665.1| (AL354829) bA218B22.1.2 (novel protein (pre... 117 3e-25
pir||T43168 hypothetical protein cyk-1 - Caenorhabditis ele... 116 7e-25
pir||T16038 hypothetical protein F11H8.4 - Caenorhabditis e... 116 7e-25
emb|CAB39108.1| (AL031053) dJ267M20.1 (diaphanous (Drosophi... 115 9e-25
gb|AAB64026.1| (AC002333) unknown protein [Arabidopsis thal... 115 2e-24
sp|Q05858|FORM_CHICK FORMIN (LIMB DEFORMITY PROTEIN) >gi|10... 113 5e-24
pir||S24286 limb deformity protein - chicken >gi|7512224|pi... 112 1e-23
gb|AAF51054.1| (AE003578) capu gene product [Drosophila mel... 111 2e-23
pir||T13286 cappuccino gene protein - fruit fly (Drosophila... 111 2e-23
dbj|BAA22512.1| (D38411) 'Ppf3p' [Saccharomyces cerevisiae] 109 5e-23
ref|NP_014128.1| contains formin homology domains; homologo... 109 5e-23
gb|AAA34455.1| (L31766) synthetic lethal 39 [Saccharomyces ... 109 5e-23
gb|AAF24497.1|AF213696_1 (AF213696) FH protein NFH2 [Nicoti... 108 1e-22
dbj|BAB01984.1| (AP002460) contains similarity to human dia... 108 2e-22
gb|AAF14548.1| (AF174427) formin-like protein AHF1 [Arabido... 108 2e-22
dbj|BAB09344.1| (AB016879) contains similarity to unknown p... 105 1e-21
ref|NP_012107.1| involved in actin filament organization; B... 103 4e-21
sp|Q10059|CC12_SCHPO CELL DIVISION CONTROL PROTEIN 12 >gi|7... 103 5e-21
>pir||T47166 hypothetical protein DKFZp762B245.1 - human (fragment)
emb|CAB82400.1| (AL162062) hypothetical protein [Homo sapiens]
Length = 425
Score = 840 bits (2146), Expect = 0.0
Identities = 425/425 (100%), Positives = 425/425 (100%)
Query: 76 DKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICR 135
DKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICR
Sbjct: 1 DKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICR 60
Query: 136 AIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERL 195
AIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERL
Sbjct: 61 AIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERL 120
Query: 196 TQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRG 255
TQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRG
Sbjct: 121 TQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRG 180
Query: 256 AVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLEN 315
AVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLEN
Sbjct: 181 AVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLEN 240
Query: 316 VLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFG 375
VLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFG
Sbjct: 241 VLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFG 300
Query: 376 ESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRN 435
ESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRN
Sbjct: 301 ESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRN 360
Query: 436 KWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTARTAKRGSRFFCDAAHH 495
KWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTARTAKRGSRFFCDAAHH
Sbjct: 361 KWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTARTAKRGSRFFCDAAHH 420
Query: 496 DESNC 500
DESNC
Sbjct: 421 DESNC 425
>gb|AAC34395.1| (AF056116) unknown [Takifugu rubripes]
Length = 1037
Score = 740 bits (1889), Expect = 0.0
Identities = 377/501 (75%), Positives = 437/501 (86%), Gaps = 19/501 (3%)
Query: 1 LPPPPDKCPPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTALKPNQIP 60
+P PP P APPLP A+PSV+L+V AIRIKKP IKTKFRLPVFNWTALKPNQI
Sbjct: 555 IPAPPPPPPLAPPLPDASPSVILSV-----AIRIKKP--IKTKFRLPVFNWTALKPNQI- 606
Query: 61 SGTVFSELDDEKILE-DKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL 119
+GTVF+E+DDE+ LE ++FEELFKT+AQGP +DL C+K+K AQKA +KVT+L+ANR+KNL
Sbjct: 607 NGTVFNEIDDERELELERFEELFKTRAQGPIMDLSCTKSKVAQKAVNKVTILDANRSKNL 666
Query: 120 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL 179
AITLRKA + TFDL+TLPVDFVECLMRFLPTE EVK LRQYERER+PL++L
Sbjct: 667 AITLRKANK----------TFDLKTLPVDFVECLMRFLPTEMEVKALRQYERERRPLDQL 716
Query: 180 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML 239
A EDRFMLLFSK+ERLTQRM + F+GNF DN+ MLTPQLNAIIAASASVKSS KLK+ML
Sbjct: 717 AEEDRFMLLFSKIERLTQRMNIITFIGNFSDNVAMLTPQLNAIIAASASVKSSPKLKRML 776
Query: 240 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW 299
EIILALGNYMNSSKRG VYGFKLQSLDLLLDTKSTDRKMTLLH+IAL VKEKYP+LANF+
Sbjct: 777 EIILALGNYMNSSKRGCVYGFKLQSLDLLLDTKSTDRKMTLLHYIALIVKEKYPELANFY 836
Query: 300 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD 359
+ELHFV+KAAAVSLENVLLDV+ELG+GM+LIRRECS+HD+SVL+ FL ++ +LDK+QRD
Sbjct: 837 NELHFVDKAAAVSLENVLLDVRELGKGMDLIRRECSLHDHSVLKGFLQASDTQLDKVQRD 896
Query: 360 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL 419
AKTAEEA+N VV YFGES KT PPSVFFPVFVRF+++YK+A +ENE RKKQE+ MREK L
Sbjct: 897 AKTAEEAFNNVVNYFGESAKTAPPSVFFPVFVRFLKAYKDAVEENELRKKQEQAMREKLL 956
Query: 420 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTA 479
A+EAK+ D K +Q+ + QQ ELIAELR+RQAK+HRPVYEGKDGTIEDIITVLKSVPFTA
Sbjct: 957 AEEAKQQDPKVQAQKKRQQQHELIAELRKRQAKDHRPVYEGKDGTIEDIITVLKSVPFTA 1016
Query: 480 RTAKRGSRFFCDAAHHDESNC 500
RTAKRGSRFFC+A D++NC
Sbjct: 1017 RTAKRGSRFFCEANLCDDANC 1037
>ref|NP_062653.1| formin-related gene in leukocytes; lymphocyte specific formin related
protein [Mus musculus]
pir||T13963 formin related protein, lymphocyte specific - mouse
gb|AAD01273.1| (AF006466) lymphocyte specific formin related protein [Mus musculus]
Length = 1064
Score = 522 bits (1329), Expect = e-147
Identities = 276/510 (54%), Positives = 360/510 (70%), Gaps = 23/510 (4%)
Query: 2 PPPPDKC-------PPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTAL 54
PPPP PP PP PG P ++ P + +K PI+TKFR+P+ NW AL
Sbjct: 561 PPPPPPLGTDGPVPPPPPPPPGGPPDILGGQGPNIGP-GVKAKKPIQTKFRMPLLNWVAL 619
Query: 55 KPNQIPSGTVFSELDDEKILED----KFEELFKTKAQGPALDLICSKNKTAQKAASKVTL 110
KP+QI +GTVF+EL+DEK+L++ FEE FKTK+QGP LD+ K K +QKA +K L
Sbjct: 620 KPSQI-TGTVFTELNDEKVLQELDMNDFEEHFKTKSQGPCLDISALKGKASQKAPTKTIL 678
Query: 111 LEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYE 170
+EANRAKNLAITLRK A+ IC+AI T+DLQTL +DF+E L RFLPT+ E L+ ++E
Sbjct: 679 IEANRAKNLAITLRKGNLGADRICQAIETYDLQTLSLDFLELLTRFLPTDYERSLIARFE 738
Query: 171 RERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVK 230
+E++P+EEL+ EDRFML FS+++RL +RM + FLGNF D Q+L PQLNAIIAAS S+K
Sbjct: 739 KEQRPMEELSEEDRFMLRFSRIQRLPERMNTLTFLGNFPDTAQLLMPQLNAIIAASMSIK 798
Query: 231 SSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKE 290
SS KL+Q+LEI+LA GNYMNSSKRGA YGF+LQSLD LL+ KSTDRK TLLH++ + E
Sbjct: 799 SSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMKSTDRKQTLLHYLVKVIAE 858
Query: 291 KYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNS-VLRNFLSTN 349
KYP L F +LHF++KA +VSL++VL DV+ L RG+EL +RE D+ VL+ FL N
Sbjct: 859 KYPQLTGFHSDLHFLDKAGSVSLDSVLGDVRSLQRGLELTQREFVRQDDCLVLKEFLRAN 918
Query: 350 EGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKK 409
+DKL D+KTA+EAY +VV YFGE+PKTT PS+ F +F RF ++YK+AEQE E KK
Sbjct: 919 SPTMDKLLADSKTAQEAYESVVEYFGENPKTTSPSMLFSLFSRFTKAYKKAEQEVEQWKK 978
Query: 410 QEEVMREKQLAQEAKKLDAKTPSQ--RNKWQQQELIAELRRRQAKEHRPVYEGKDGTIED 467
+ A + + + TP + + QQ +LI+EL+R+Q KE +DG IED
Sbjct: 979 E-------AAADTSGREEPPTPKSPPKARRQQMDLISELKRKQQKEPLIYESDRDGAIED 1031
Query: 468 IITVLKSVPFTARTAKRGSRFFCDAAHHDE 497
IITVLK+VPFTART KR SR C+A+ +E
Sbjct: 1032 IITVLKTVPFTARTGKRTSRLLCEASLGEE 1061
>gb|AAF25953.1| (AF215666) formin-like protein [Mus musculus]
Length = 1094
Score = 498 bits (1268), Expect = e-140
Identities = 266/501 (53%), Positives = 351/501 (69%), Gaps = 24/501 (4%)
Query: 2 PPPPDKC-------PPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTAL 54
PPPP PP PP PG P ++ P + +K PI+TKFR+P+ NW AL
Sbjct: 587 PPPPPPLGTDGPVPPPPPPPPGGPPDILGGQGPDIGP-GVKAKKPIQTKFRMPLLNWVAL 645
Query: 55 KPNQIPSGTVFSELDDEKILED----KFEELFKTKAQGPALDLICSKNKTAQKAASKVTL 110
KP+QI +GTVF+EL+DEK+L++ FEE FKTK+QGP LD+ K K +QKA +K L
Sbjct: 646 KPSQI-TGTVFTELNDEKVLQELDMNDFEEHFKTKSQGPCLDISALKGKASQKAPTKTIL 704
Query: 111 LEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYE 170
+EANRAKNLAITLRK A+ IC+AI T+DLQTL +DF+E L RFLPT+ E L+ ++E
Sbjct: 705 IEANRAKNLAITLRKGNLGADRICQAIETYDLQTLSLDFLELLTRFLPTDYERSLIARFE 764
Query: 171 RERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVK 230
+E++P+EEL+ EDRFML FS+++RL +RM + FLGNF D Q+L PQLNAIIAAS S+K
Sbjct: 765 KEQRPMEELSEEDRFMLRFSRIQRLPERMNTLTFLGNFPDTAQLLMPQLNAIIAASMSIK 824
Query: 231 SSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKE 290
SS KL+Q+LEI+LA GNYMNSSKRGA YGF+LQSLD LL+ KSTDRK TLLH++ + E
Sbjct: 825 SSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMKSTDRKQTLLHYLVKVIAE 884
Query: 291 KYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNS-VLRNFLSTN 349
KYP L F +LHF++KA +VSL++VL DV+ L RG+EL +RE D+ VL+ FL N
Sbjct: 885 KYPQLTGFHSDLHFLDKAGSVSLDSVLGDVRSLQRGLELTQREFVRQDDCLVLKEFLRAN 944
Query: 350 EGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKK 409
+DKL D+KTA+EAY +VV YFGE+PKTT PS+FF +F RF ++YK+AEQE E KK
Sbjct: 945 SPTMDKLLADSKTAQEAYESVVEYFGENPKTTSPSMFFSLFSRFTKAYKKAEQEVEQWKK 1004
Query: 410 QEEVMREKQLAQEAKKLDAKTPSQ--RNKWQQQELIAELRRRQAKEHRPVYEGKDGTIED 467
+ A + + + TP + + QQ +LI+EL+R+Q KE +DG IED
Sbjct: 1005 E-------AAADTSGREEPPTPKSPPKARRQQMDLISELKRKQQKEPLIYESDRDGAIED 1057
Query: 468 IITVLKSVPF-TARTAKRGSR 487
IIT L++ P+ A T +R +R
Sbjct: 1058 IITDLRNQPYIRADTGRRSAR 1078
>ref|NP_005883.1| formin-like; chromosome 17 open reading frame 1; chromosome 17
open reading frame 1B [Homo sapiens]
ref|XP_008347.1| chromosome 17 open reading frame 1B [Homo sapiens]
emb|CAA07870.1| (AJ008112) C17orf1 protein [Homo sapiens]
Length = 463
Score = 476 bits (1213), Expect = e-133
Identities = 254/450 (56%), Positives = 327/450 (72%), Gaps = 11/450 (2%)
Query: 46 LPVFNWTALKPNQIPSGTVFSELDDEKILED----KFEELFKTKAQGPALDLICSKNKTA 101
+P+ NW ALKP+QI +GTVF+EL+DEK+L++ FEE FKTK+QGP+LDL K+K A
Sbjct: 1 MPLLNWVALKPSQI-TGTVFTELNDEKVLQELDMSDFEEQFKTKSQGPSLDLSALKSKAA 59
Query: 102 QKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEA 161
QKA SK TL+EANRAKNLAITLRK AE IC+AI +DLQ L +DF+E LMRFLPTE
Sbjct: 60 QKAPSKATLIEANRAKNLAITLRKGNLGAERICQAIEAYDLQALGLDFLELLMRFLPTEY 119
Query: 162 EVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNA 221
E L+ ++ERE++P+EEL+ EDRFML FS++ RL +RM + FLGNF D Q+L PQLNA
Sbjct: 120 ERSLITRFEREQRPMEELSEEDRFMLCFSRIPRLPERMTTLTFLGNFPDTAQLLMPQLNA 179
Query: 222 IIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLL 281
IIAAS S+KSS KL+Q+LEI+LA GNYMNSSKRGA YGF+LQSLD LL+ KSTDRK TLL
Sbjct: 180 IIAASMSIKSSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMKSTDRKQTLL 239
Query: 282 HFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDN-S 340
H++ + EKYP L F +LHF++KA +VSL++VL DV+ L RG+EL +RE D+
Sbjct: 240 HYLVKVIAEKYPQLTGFHSDLHFLDKAGSVSLDSVLADVRSLQRGLELTQREFVRQDDCM 299
Query: 341 VLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEA 400
VL+ FL N +DKL D+KTA+EA+ +VV YFGE+PKTT P +FF +F RFI++YK+A
Sbjct: 300 VLKEFLRANSPTMDKLLADSKTAQEAFESVVEYFGENPKTTSPGLFFSLFSRFIKAYKKA 359
Query: 401 EQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQ--QQELIAELRRRQAKEHRPVY 458
EQE E KK E ++ A K + P K + Q +LI+EL+RRQ KE
Sbjct: 360 EQEVEQWKK--EAAAQEAGADTPGKGEPPAPKSPPKARRPQMDLISELKRRQQKEPLIYE 417
Query: 459 EGKDGTIEDIITVLKSVPF-TARTAKRGSR 487
+DG IEDIIT L++ P+ A T +R +R
Sbjct: 418 SDRDGAIEDIITDLRNQPYIRADTGRRSAR 447
>gb|AAF49761.1| (AE003536) CG6807 gene product [Drosophila melanogaster]
Length = 1043
Score = 371 bits (943), Expect = e-102
Identities = 217/539 (40%), Positives = 324/539 (59%), Gaps = 60/539 (11%)
Query: 2 PPPPDKCPPAPPLPGA-----APSVVLT--------VPPGLSAIRIKKPP---------- 38
PPPP PPAPP P +PS L PP LS+ + PP
Sbjct: 494 PPPPPPAPPAPPPPPGFSPLGSPSGSLASTAPSPPHAPPMLSSFQPPPPPVAGFMPAPDG 553
Query: 39 ------PIKTKFRLPVFNWTALKPNQIPSGTVFSELDDEKILE----DKFEELFK----- 83
+ TK++LP NW ALKPNQ+ GT+F+ELDDEKI + ++FEE FK
Sbjct: 554 AMTIKRKVPTKYKLPTLNWIALKPNQV-RGTIFNELDDEKIFKQIDFNEFEERFKIGIGG 612
Query: 84 ---TKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTF 140
+ G +D +K K V+LLE R +N+AI+ RK G +++ AIH+
Sbjct: 613 ALRNGSNGTEVDGSLQSSKRF-KRPDNVSLLEHTRLRNIAISRRKLGMPIDDVIAAIHSL 671
Query: 141 DLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMA 200
DL+ L ++ VE L + +PT+AEVK ++Y ER+ + L ED+FML S+VER++ ++A
Sbjct: 672 DLKKLSLENVELLQKMVPTDAEVKSYKEYIIERKDQQLLTEEDKFMLQLSRVERISSKLA 731
Query: 201 GMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGF 260
M ++GNF D++ +++PQ+ +I AS S+K S+K K +LEI+LA GNY+NS+KRG YGF
Sbjct: 732 IMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGNYLNSNKRGPAYGF 791
Query: 261 KLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDV 320
KLQSLD L+DTKSTD++ +LLH+I T++ K+P+L NF EL+ +KAA+V+LENV+ DV
Sbjct: 792 KLQSLDTLIDTKSTDKRSSLLHYIVATIRAKFPELLNFESELYGTDKAASVALENVVADV 851
Query: 321 KELGRGMELIRRECSIH----DNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGE 376
+EL +GM+L+R+E + +LR+FL+ +E KL K++ D + A+EA+ V YFG+
Sbjct: 852 QELEKGMDLVRKEAELRVKGAQTHILRDFLNNSEDKLKKIKSDLRHAQEAFKECVEYFGD 911
Query: 377 SPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRN- 435
S + + FF + VRF R++K+ +QENE R + EK A A K + RN
Sbjct: 912 SSRNADAAAFFALIVRFTRAFKQHDQENEQR-----LRLEKAAALAASKKENDQVLMRNK 966
Query: 436 ---KWQQQELIAELRRR--QAKEHRPVYEGK--DGTIEDIITVLKSVPFTARTAKRGSR 487
K QQ+ +I EL+ + +E + + + + +G +EDI+ LKS P+ A R S+
Sbjct: 967 VNQKKQQEAVINELKSKAHSVREKKLLQQDEVYNGALEDILLGLKSEPYRRADAVRRSQ 1025
>gb|AAF60718.1| (AC024798) contains similarity to TR:Q9Z2V7 [Caenorhabditis elegans]
Length = 1164
Score = 250 bits (633), Expect = 2e-65
Identities = 162/476 (34%), Positives = 249/476 (52%), Gaps = 42/476 (8%)
Query: 2 PPPPDKC---PPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTALKPNQ 58
PPPP PP PP PG L P A IKK +TK +LP NWTA+KP Q
Sbjct: 553 PPPPPMLGGPPPPPPPPGG-----LMGPASNDAKTIKKI--YQTKNKLPQLNWTAMKPMQ 605
Query: 59 IPSGTVFSELDDEKILE----DKFEELFKTKAQGPALDLICSKNKTA------------- 101
+ TVF +L+DE I+E K EE+FK P L L K++ +
Sbjct: 606 AKN-TVFEKLNDELIIEKLDFSKLEEMFKLAQ--PTLGLAEPKSEQSVIGQVSPGSTTSA 662
Query: 102 --QKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPT 159
+A K TLL+ R +N+AIT RK A+ I A+H +L L + V+ L R LPT
Sbjct: 663 AGTSSARKNTLLDTKRLQNVAITRRKVAMDAKSIMAAVHQLNLSALSAEKVDILSRILPT 722
Query: 160 EAEVKLL--RQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTP 217
+ E KL ++ +E L+ +D F+ ++ERL ++A M + F ++ +L P
Sbjct: 723 DEERKLYAGKKTTESENSMENLSEDDNFVAALCEIERLEHKLAVMRVMSEFDESAGLLEP 782
Query: 218 QLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKS-TDR 276
Q + AAS + +Q +LE+ILA GNYMNS KRG YGFKL SLD L K+ DR
Sbjct: 783 QFTHVTAASKCAREAQLFHGVLEVILAFGNYMNSGKRGGAYGFKLSSLDSLAILKAPADR 842
Query: 277 KMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSI 336
+TLLH I +++ P L F +L FV+KA +V ++V D+KEL G ++ +E +
Sbjct: 843 SLTLLHMIVAEIEKNLPHLKTFSEQLKFVDKATSVQWDSVQTDMKELAAGFKMAEKEQEL 902
Query: 337 HDN---SVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRF 393
L F ++ + K+ L++ + A ++ ++GE+ K+T P+VFF F
Sbjct: 903 KGTDCPEALSTFTASRKQKMADLEQAFQLAASSFKDCCEFYGENEKSTSPTVFFQKLAHF 962
Query: 394 IRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIAELRRR 449
+++Y++ ENEA+ E+ R+++ + A+ K+ + +Q +L+ EL +
Sbjct: 963 VQNYQKCRGENEAKAALEK-RRQEEAERRARVASTKSSASS---EQDQLMMELAEK 1014
>dbj|BAA31641.1| (AB014566) KIAA0666 protein [Homo sapiens]
Length = 1085
Score = 233 bits (588), Expect = 4e-60
Identities = 156/504 (30%), Positives = 262/504 (51%), Gaps = 53/504 (10%)
Query: 1 LPPPPDKCPPA--PPLPGAAPSVVLTVPPGLS-AIRIKKPPPIKTKFRLPVFNWTALKPN 57
LPPPP PP PP PG P + PPG + +KK + L FNW+ L N
Sbjct: 569 LPPPPPPLPPGGPPPPPGPPPLGAIMPPPGAPMGLALKKKSIPQPTNALKSFNWSKLPEN 628
Query: 58 QIPSGTVFSELDDEKILED-KFEELFKT-KAQGPALDLICSKNKTAQKA----------- 104
++ GTV++E+DD K+ + E+L +T A D + N ++A
Sbjct: 629 KL-EGTVWTEIDDTKVFKILDLEDLERTFSAYQRQQDFFVNSNSKQKEADAIDDTLSSKL 687
Query: 105 -ASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQT-LPVDFVECLMRFLPTEAE 162
++++++ RA+N I L + S +EI RAI T D Q LP D +E L++F+P +++
Sbjct: 688 KVKELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSD 747
Query: 163 VKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAI 222
+ LL +++ E L+ +A DRF+ S++ QR+ + F F + + + P++ AI
Sbjct: 748 IDLLEEHKHE---LDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAI 804
Query: 223 IAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKST-DRKMTLL 281
+ S V S LKQ+LE++LA GNYMN +RG YGFK+ SL+ + DTKS+ D+ +TLL
Sbjct: 805 RSGSEEVFRSGALKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLL 864
Query: 282 HFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDN-- 339
H++ V+ KYP + N EL + +AA V++ + ++ L G++ + E +
Sbjct: 865 HYLITIVENKYPSVLNLNEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQP 924
Query: 340 --------SVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFV 391
SV+ F++ ++ A++ + V++FGE P FF +F
Sbjct: 925 PQPGDKFVSVVSQFITVASFSFSDVEDLLAEAKDLFTKAVKHFGEEAGKIQPDEFFGIFD 984
Query: 392 RFIRSYKEAEQENE-ARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIAELRRRQ 450
+F+++ EA+QENE RKK+EE R +++A+ QR + E + R+
Sbjct: 985 QFLQAVSEAKQENENMRKKKEEEERR-------ARMEAQLKEQRER--------ERKMRK 1029
Query: 451 AKEHRPVYEGKDGTIEDIITVLKS 474
AKE+ + G +D+++ L+S
Sbjct: 1030 AKEN----SEESGEFDDLVSALRS 1049
>dbj|BAA20835.1| (AB002379) KIAA0381 [Homo sapiens]
Length = 864
Score = 230 bits (581), Expect = 2e-59
Identities = 159/522 (30%), Positives = 266/522 (50%), Gaps = 68/522 (13%)
Query: 1 LPPPPDKCP-------PAPPLPGAAPSVVLTVPPGL-------------SAIRIKKPPPI 40
LPPPP P P PPLP P PP L S + ++K
Sbjct: 327 LPPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVPLRKKRVP 386
Query: 41 KTKFRLPVFNWTALKPNQIPSGTVFSELDDEKI-----LEDKFEELFKTKAQGPALDLIC 95
+ L FNW L ++P GTV++E+DD ++ LED FE++F + L
Sbjct: 387 QPSHPLKSFNWVKLNEERVP-GTVWNEIDDMQVFRILDLED-FEKMFSAYQRHQELITNP 444
Query: 96 SKNKT---------AQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQT-L 145
S+ K A + ++++++ RA+N I L K S EEI +AI D Q L
Sbjct: 445 SQQKELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDL 504
Query: 146 PVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFL 205
D +E L++F+P ++++ LL +++ E +E +A DRF+ S+++ QR+ + F
Sbjct: 505 AKDMLEQLLKFIPEKSDIDLLEEHKHE---IERMARADRFLYEMSRIDHYQQRLQALFFK 561
Query: 206 GNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSL 265
FQ+ L P++ AI+ AS + S++L+QMLE+ILA+GN+MN +RG YGF++ SL
Sbjct: 562 KKFQERLAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFRVASL 621
Query: 266 DLLLDTKST-DRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELG 324
+ + DTKS+ DR ++LLH++ + +++ +PD+ N EL + +AA V+L + +V L
Sbjct: 622 NKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLR 681
Query: 325 RGMELIR----------RECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYF 374
RG+ + RE S V+ +F++ + +L+ A + + + +F
Sbjct: 682 RGLRAVEVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHF 741
Query: 375 GESPKTTPPSVFFPVFVRFIRSYKEAEQENEA--RKKQEEVMREKQLAQEAKKLDAKTPS 432
GE P FF +F F++++ EA Q+ EA R+K+EE R + A K
Sbjct: 742 GEHDSKMQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERRARMEAM------LKEQR 795
Query: 433 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKS 474
+R +WQ+Q R+ + EG G +D+++ L+S
Sbjct: 796 ERERWQRQ-------RKVLAAGSSLEEG--GEFDDLVSALRS 828
>gb|AAF45601.1| (AE003420) EG:114D9.2 gene product [Drosophila melanogaster]
Length = 1429
Score = 206 bits (519), Expect = 4e-52
Identities = 148/478 (30%), Positives = 239/478 (49%), Gaps = 52/478 (10%)
Query: 1 LPPPPDKCPPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTALKPNQIP 60
+PPPP CP APP P + + PP + + P P L FNW+ L P+
Sbjct: 864 MPPPPPPCPGAPPPPPSMAQTMAPAPPKVDLPKKNVPQPTNP---LKSFNWSKL-PDAKL 919
Query: 61 SGTVFSELDDEKILE----DKFEELFKTKAQG--PALDLICSKNKTAQKAASK--VTLLE 112
GTV+SELD+ K+ + ++LF + A D + KAA + +++++
Sbjct: 920 QGTVWSELDESKLYNNMELESIDKLFSAYQKNGVSATDGSYEDLRVTGKAAKQKVLSVID 979
Query: 113 ANRAKNLAITLRKAGRSAEEICRAIHTFDL-QTLPVDFVECLMRFLPTEAEVKLLRQYER 171
RA+N I L K S EI +AI + D + L +D VE L++F P+ E LL ++
Sbjct: 980 GRRAQNCTILLSKLKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSE 1039
Query: 172 ERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKS 231
+ +E LA DRF+ SK+ QR+ + + F + L P++ +++ AS V
Sbjct: 1040 D---IESLARADRFLYEISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVAR 1096
Query: 232 SQKLKQMLEIILAL--------------------GNYMNSSKRGAVYGFKLQSLDLLLDT 271
S++L+++LE++LAL GNYMN RG GF+L SL+ L DT
Sbjct: 1097 SRRLRKLLELVLALGMIHCPFAKHSITQTTSIPPGNYMNRGARGNASGFRLASLNRLADT 1156
Query: 272 KSTDRK-MTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELI 330
KS+ K TLLH++ ++ K+ DL ++ V +A+ VSL + D++ L G+ +
Sbjct: 1157 KSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRTGLADV 1216
Query: 331 RRECSIHDNS-----------VLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPK 379
RE H +S V+R F + + +L+ + + ++ VR FGE
Sbjct: 1217 AREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDKFQDMKTRFDRAVRLFGEDGS 1276
Query: 380 TTPPSVFFPVFVRFIRSYKEAEQENEA-RKKQEEVMREKQLAQEAKKLDAKTPSQRNK 436
P FF +F F+ ++ EA +NE+ R++QEE EK+ QEA +L +T ++NK
Sbjct: 1277 VLQPDEFFGIFDSFLAAFAEARHDNESFRRRQEE--EEKRAKQEA-ELKKRTIERKNK 1331
>emb|CAA21052.1| (AL031640) /prediction=(method:""genscan"", version:""1.0"",
score:""400.91"")~/prediction=(method:""genefinder"",
version:""084"")~/match=(desc:""DIA-12C PROTEIN"",
species:""HOMO SAPIENS (HUMAN)"",
ranges:(query:29998..30156, target:SPTREMBL::O60878:>
Length = 979
Score = 206 bits (519), Expect = 4e-52
Identities = 148/478 (30%), Positives = 239/478 (49%), Gaps = 52/478 (10%)
Query: 1 LPPPPDKCPPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTALKPNQIP 60
+PPPP CP APP P + + PP + + P P L FNW+ L P+
Sbjct: 414 MPPPPPPCPGAPPPPPSMAQTMAPAPPKVDLPKKNVPQPTNP---LKSFNWSKL-PDAKL 469
Query: 61 SGTVFSELDDEKILE----DKFEELFKTKAQG--PALDLICSKNKTAQKAASK--VTLLE 112
GTV+SELD+ K+ + ++LF + A D + KAA + +++++
Sbjct: 470 QGTVWSELDESKLYNNMELESIDKLFSAYQKNGVSATDGSYEDLRVTGKAAKQKVLSVID 529
Query: 113 ANRAKNLAITLRKAGRSAEEICRAIHTFDL-QTLPVDFVECLMRFLPTEAEVKLLRQYER 171
RA+N I L K S EI +AI + D + L +D VE L++F P+ E LL ++
Sbjct: 530 GRRAQNCTILLSKLKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSE 589
Query: 172 ERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKS 231
+ +E LA DRF+ SK+ QR+ + + F + L P++ +++ AS V
Sbjct: 590 D---IESLARADRFLYEISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVAR 646
Query: 232 SQKLKQMLEIILAL--------------------GNYMNSSKRGAVYGFKLQSLDLLLDT 271
S++L+++LE++LAL GNYMN RG GF+L SL+ L DT
Sbjct: 647 SRRLRKLLELVLALGMIHCPFAKHSITQTTSIPPGNYMNRGARGNASGFRLASLNRLADT 706
Query: 272 KSTDRK-MTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELI 330
KS+ K TLLH++ ++ K+ DL ++ V +A+ VSL + D++ L G+ +
Sbjct: 707 KSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRTGLADV 766
Query: 331 RRECSIHDNS-----------VLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPK 379
RE H +S V+R F + + +L+ + + ++ VR FGE
Sbjct: 767 AREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDKFQDMKTRFDRAVRLFGEDGS 826
Query: 380 TTPPSVFFPVFVRFIRSYKEAEQENEA-RKKQEEVMREKQLAQEAKKLDAKTPSQRNK 436
P FF +F F+ ++ EA +NE+ R++QEE EK+ QEA +L +T ++NK
Sbjct: 827 VLQPDEFFGIFDSFLAAFAEARHDNESFRRRQEE--EEKRAKQEA-ELKKRTIERKNK 881
>gb|AAC69221.2| (AF101312) contains similarity to human diaphanous 1 (GB:AF051782)
[Caenorhabditis elegans]
Length = 1034
Score = 180 bits (451), Expect = 4e-44
Identities = 130/479 (27%), Positives = 236/479 (49%), Gaps = 43/479 (8%)
Query: 3 PP--PDKCPPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTALKPNQIP 60
PP P CPPAPP P P LT PP + + +PP + NW L ++
Sbjct: 541 PPLLPPVCPPAPP-PPPPPIGGLTSPPKDALKNVPEPPG-----NMKTLNWQRLTLDKT- 593
Query: 61 SGTVFSELDDEKILED----KFEELFKTKAQGPALD---LICSKNKTAQKAASKVTLLEA 113
GTV+ +DDEKI + + F + D L + N+ Q+A +T+++
Sbjct: 594 RGTVWDGIDDEKIYKQLDLTELSGCFAASSSHKDEDTDTLYGTINRRPQQA--NITVIDP 651
Query: 114 NRAKNLAITLRKAGRSAEEICRAIHTFDLQT-LPVDFVECLMRFLPTEAEVKLLRQYERE 172
R +N I L K S +EI +A+ + D + LP D +E +++F+PT+ E+ + + ++
Sbjct: 652 RRYQNCTIMLSKLKLSHKEIKQAMMSMDEKCKLPKDMIEQMLKFMPTKEELTQINESVQK 711
Query: 173 RQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSS 232
LA DR+M S + R QR+ + + +F D ++ L P + ++ A++S + +
Sbjct: 712 HGSPTVLALADRYMYEISSIPRFEQRLRCLNIIRSFHDRVEALVPFIQVVLKATSSCQQN 771
Query: 233 QKLKQMLEIILALGNYMNSSKR-GAVYGFKLQSLDLLLDTKSTDRK-MTLLHFIALTVKE 290
++ +Q+L IILA+GNY+N KR G YGF++ S++ L D K+ R LLHF+ +++
Sbjct: 772 KRFRQILTIILAIGNYLNFGKRNGNAYGFEMASINKLADVKNALRNDRNLLHFLVNFIEK 831
Query: 291 KYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNS---------- 340
KYPDL F + V +AA S +++ L + ++R+E ++ +++
Sbjct: 832 KYPDLTKFKKDFATVTEAARFSQSETAAEIRNLEEALLIVRKELNLLESTTKVELPEHIP 891
Query: 341 --------VLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPK--TTPPSVFFPVF 390
V + F+ + L + + + ++ +YF SP P FF V
Sbjct: 892 PENDRFALVAKAFIEKATAEYHNLDKMFREMKNKFSDCAKYFCYSPSGGVPVPEEFFSVI 951
Query: 391 VRFIRSYKEAEQENEARKKQEEVMREKQLAQE--AKKLDAKTPSQRNKWQQQELIAELR 447
+F+ ++ E Q+ A ++EE ++ + +A+ AKK + + ++LI+ L+
Sbjct: 952 NKFLNTFNEYHQQLWAEVEEEEKIKRQTIARSFLAKKSTTRRKENHKERDFEQLISALQ 1010
>ref|NP_062644.1| diaphanous homolog 3 (Drosophila); diaphanous-related formin [Mus
musculus]
pir||T17454 diaphanous-related formin - mouse
gb|AAC71771.1| (AF094519) diaphanous-related formin; p134 mDia2 [Mus musculus]
Length = 1171
Score = 179 bits (449), Expect = 7e-44
Identities = 126/463 (27%), Positives = 222/463 (47%), Gaps = 31/463 (6%)
Query: 2 PPPPDKCPPAPPLPGAAPSVVLTVPP--------GLSAIRIKKPPPIKTK------FRLP 47
PPPP PP PPLPG VPP G S+I + P +K K +
Sbjct: 567 PPPPPPPPPPPPLPGMPMPFGGPVPPPPPLGFLGGQSSIPLNLPFGLKPKKEFKPEISMR 626
Query: 48 VFNWTALKPNQIPSGTVFSELDDEKI----LEDKFEELFKTKAQGPALDLICSKNKTAQK 103
NW + PN++ + ++++ K L K E F + + + K +K
Sbjct: 627 RLNWLKIGPNEMSENCFWIKVNENKYENRDLLCKLENTFCCQEKEKRNTNDFDEKKVIKK 686
Query: 104 AASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEV 163
++ L+ A+NL+I L E+I I D L ++ L++ LP E ++
Sbjct: 687 RMKELKFLDPKIAQNLSIFLSSFRVPYEKIRTMILEVDETQLSESMIQNLIKHLPDEEQL 746
Query: 164 KLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAII 223
K L Q+ R L ++F ++ S V+RL R++ + F F++ + + P + A+
Sbjct: 747 KSLSQF---RSDYNSLCEPEQFAVVMSNVKRLRPRLSAILFKLQFEEQVNNIKPDIMAVS 803
Query: 224 AASASVKSSQKLKQMLEIILALGNYMNSSKRGA-VYGFKLQSLDLLLDTKSTDRKMTLLH 282
A +K S+ ++LE++L +GNYMN+ R A +GF L SL L DTKS D+K TLLH
Sbjct: 804 TACEEIKKSKGFSKLLELVLLMGNYMNAGSRNAQTFGFDLSSLCKLKDTKSADQKTTLLH 863
Query: 283 FIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRREC-------S 335
F+ +EK+ D+ +F +L ++KA+ VS+E + +VK++GR ++ + +
Sbjct: 864 FLVDVCEEKHADILHFVDDLAHLDKASRVSVEMLEKNVKQMGRQLQQLEKNLETFPPPED 923
Query: 336 IHDNSVLR--NFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRF 393
+HD V++ +F+ + + +KL + + Y +++ Y+ K FF F
Sbjct: 924 LHDKFVIKMSSFVISANEQYEKLSTLLGSMTQLYQSIMGYYAVDMKKVSVEEFFNDLNNF 983
Query: 394 IRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNK 436
S+ A +EN +++ E + ++A+E + + Q K
Sbjct: 984 RTSFMLALKENIKKREAAEKEKRARIAKERAEKERLERQQEKK 1026
>ref|NP_005210.1| diaphanous 1; Diaphanous, Drosophila, homolog of, 1; deafness,
autosomal dominant 1; hDia1 [Homo sapiens]
sp|O60610|DIA1_HUMAN DIAPHANOUS PROTEIN HOMOLOG 1
gb|AAC05373.1| (AF051782) diaphanous 1 [Homo sapiens]
Length = 1248
Score = 175 bits (439), Expect = 1e-42
Identities = 128/458 (27%), Positives = 219/458 (46%), Gaps = 39/458 (8%)
Query: 2 PPPPDKCPPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTALKPNQIPS 61
PPPP P PP G +P GL+ ++ KP + + R P NW+ L +
Sbjct: 719 PPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKP---EVQLRRP--NWSKLVAEDLSQ 773
Query: 62 GTVFSELDDEKILEDKFE--ELF-----------KTKAQGPALDLICSKNKTAQKAASKV 108
++ K+ ED+FE ELF KTK + K +K ++
Sbjct: 774 DCFWT-----KVKEDRFENNELFAKLTLTFSAQTKTKKDQEGGE---EKKSVQKKKVKEL 825
Query: 109 TLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQ 168
+L++ A+NL+I L +EI I + L ++ L++ +P ++K+L +
Sbjct: 826 KVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSE 885
Query: 169 YERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASAS 228
+ E ++LA ++F ++ V RL R+ + F F + ++ + P++ ++ AA
Sbjct: 886 LKDE---YDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEE 942
Query: 229 VKSSQKLKQMLEIILALGNYMNSSKRGA-VYGFKLQSLDLLLDTKSTDRKMTLLHFIALT 287
++ S+ +LEI L +GNYMN+ R A +GF + L L DTKSTD+KMTLLHF+A
Sbjct: 943 LRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAEL 1002
Query: 288 VKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSV------ 341
+ YPD+ F EL VEKA+ VS EN+ ++ ++ + + + R+ +
Sbjct: 1003 CENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKF 1062
Query: 342 ---LRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYK 398
+ +F+ + + +KL+ E Y + YF PK FF F +
Sbjct: 1063 VEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHNFRNMFL 1122
Query: 399 EAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNK 436
+A +EN+ R+K EE MR +LA+E + + Q+ +
Sbjct: 1123 QAVKENQKRRKTEEKMRRAKLAKEKAEKERLEKQQKRE 1160
Score = 42.2 bits (97), Expect = 0.014
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 11/63 (17%)
Query: 2 PPPPDKCPPAPPLPGAAPSVVLTVPPGLSA-IRIKKPPPIKTKFRLPVFNWTALKPNQIP 60
PPPP PP PPLPG ++ PP LS I PPP+ +P P+ +P
Sbjct: 600 PPPPPPPPPPPPLPG---GTAISPPPPLSGDATIPPPPPLPEGVGIP-------SPSSLP 649
Query: 61 SGT 63
GT
Sbjct: 650 GGT 652
>ref|XP_003754.1| diaphanous 1 [Homo sapiens]
Length = 1208
Score = 174 bits (436), Expect = 2e-42
Identities = 136/498 (27%), Positives = 236/498 (47%), Gaps = 53/498 (10%)
Query: 2 PPPPDKCPPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTALKPNQIPS 61
PPPP P PP G +P GL+ ++ KP + + R P NW+ L +
Sbjct: 719 PPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKP---EVQLRRP--NWSKLVAEDLSQ 773
Query: 62 GTVFSELDDEKILEDKFE--ELF-----------KTKAQGPALDLICSKNKTAQKAASKV 108
++ K+ ED+FE ELF KTK + K +K ++
Sbjct: 774 DCFWT-----KVKEDRFENNELFAKLTLTFSAQTKTKKDQEGGE---EKKSVQKKKVKEL 825
Query: 109 TLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQ 168
+L++ A+NL+I L +EI I + L ++ L++ +P ++K+L +
Sbjct: 826 KVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSE 885
Query: 169 YERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASAS 228
+ E ++LA ++F ++ V RL R+ + F F + ++ + P++ ++ AA
Sbjct: 886 LKDE---YDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEE 942
Query: 229 VKSSQKLKQMLEIILALGNYMNSSKRGA-VYGFKLQSLDLLLDTKSTDRKMTLLHFIALT 287
++ S+ +LEI L +GNYMN+ R A +GF + L L DTKSTD+KMTLLHF+A
Sbjct: 943 LRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAEL 1002
Query: 288 VKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSV------ 341
+ YPD+ F EL VEKA+ VS EN+ ++ ++ + + + R+ +
Sbjct: 1003 CENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKF 1062
Query: 342 ---LRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYK 398
+ +F+ + + +KL+ E Y + YF PK FF F +
Sbjct: 1063 VEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHNFRNMFL 1122
Query: 399 EAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIAE----------LRR 448
+A +EN+ R++ EE MR +LA+E K + Q+ + Q ++ AE L
Sbjct: 1123 QAVKENQKRRETEEKMRRAKLAKE-KAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEA 1181
Query: 449 RQAKEHRPVYEGKDGTIE 466
Q ++H +G++G ++
Sbjct: 1182 LQPEQHS---DGREGPVK 1196
Score = 36.0 bits (81), Expect = 1.0
Identities = 23/64 (35%), Positives = 30/64 (45%), Gaps = 12/64 (18%)
Query: 2 PPPPDKCPPAPP-LPGAAPSVVLTVPPGLSA-IRIKKPPPIKTKFRLPVFNWTALKPNQI 59
PPPP C +PP LPG ++ PP LS I PPP+ +P P+ +
Sbjct: 599 PPPPPPCISSPPSLPG---GTAISPPPPLSGDATIPPPPPLPEGVGIP-------SPSSL 648
Query: 60 PSGT 63
P GT
Sbjct: 649 PGGT 652
>ref|NP_006720.1| diaphanous 2 isoform 12C; Diaphanous, Drosophila, homolog of, 2 [Homo
sapiens]
sp|O60879|DIA2_HUMAN DIAPHANOUS PROTEIN HOMOLOG 2
emb|CAA75870.1| (Y15909) DIA-156 protein [Homo sapiens]
Length = 1101
Score = 173 bits (433), Expect = 5e-42
Identities = 141/493 (28%), Positives = 221/493 (44%), Gaps = 68/493 (13%)
Query: 2 PPPPDKCPPAPPLPGAAPSVVLTVP-PGLSAIRIKKPPPI-------------------- 40
PPPP PPAPPLPG AP P PG+ I PPP+
Sbjct: 562 PPPP---PPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPGI 618
Query: 41 --------------KTKFRLPVFNWTALKPNQIPSGTVFSELDDEKILEDKFE--ELFKT 84
K + + NW+ ++P ++ + ++ EDKFE +LF
Sbjct: 619 SLNLPYGMKQKKMYKPEVSMKRINWSKIEPTELSENCFWL-----RVKEDKFENPDLFAK 673
Query: 85 KAQGPALDLICSKNKTA---------QKAASKVTLLEANRAKNLAITLRKAGRSAEEICR 135
A A + KN A +K ++ +L+ A+NL+I L E+I
Sbjct: 674 LALNFATQIKVQKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIFLGSYRMPYEDIRN 733
Query: 136 AIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERL 195
I + L ++ L++ LP E K+L + + ++L ++F ++ S V+ L
Sbjct: 734 VILEVNEDMLSEALIQNLVKHLP---EQKILNELAELKNEYDDLCEPEQFGVVMSSVKML 790
Query: 196 TQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRG 255
R++ + F F++++ + P + A+ A +K S+ ++LE++L +GNYMNS R
Sbjct: 791 QPRLSSILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSRN 850
Query: 256 A-VYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS-- 312
A GFK+ L + DTKS D+K TLLHFIA +EKY D+ F EL VE A+ VS
Sbjct: 851 AQSLGFKINFLCKIRDTKSADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVSAQ 910
Query: 313 -----LENVLLDVKELGRGMELIRRECSIHDNSV--LRNFLSTNEGKLDKLQRDAKTAEE 365
L ++ + L R ++ + + HD V + +F T + +KL +
Sbjct: 911 ILKSNLASMEQQIVHLERDIKKFPQAENQHDKFVEKMTSFTKTAREQYEKLSTMHNNMMK 970
Query: 366 AYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKK 425
Y + YF KT FF F + EA +EN R++ EE R +LA+E K
Sbjct: 971 LYENLGEYFIFDSKTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAKLAKE-KA 1029
Query: 426 LDAKTPSQRNKWQ 438
K Q+ K Q
Sbjct: 1030 EQEKLERQKKKKQ 1042
>ref|NP_009293.1| diaphanous 2 isoform 12C; Diaphanous, Drosophila, homolog of, 2 [Homo
sapiens]
emb|CAA75869.1| (Y15908) DIA-12C protein [Homo sapiens]
Length = 1096
Score = 173 bits (433), Expect = 5e-42
Identities = 141/493 (28%), Positives = 221/493 (44%), Gaps = 68/493 (13%)
Query: 2 PPPPDKCPPAPPLPGAAPSVVLTVP-PGLSAIRIKKPPPI-------------------- 40
PPPP PPAPPLPG AP P PG+ I PPP+
Sbjct: 562 PPPP---PPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPGI 618
Query: 41 --------------KTKFRLPVFNWTALKPNQIPSGTVFSELDDEKILEDKFE--ELFKT 84
K + + NW+ ++P ++ + ++ EDKFE +LF
Sbjct: 619 SLNLPYGMKQKKMYKPEVSMKRINWSKIEPTELSENCFWL-----RVKEDKFENPDLFAK 673
Query: 85 KAQGPALDLICSKNKTA---------QKAASKVTLLEANRAKNLAITLRKAGRSAEEICR 135
A A + KN A +K ++ +L+ A+NL+I L E+I
Sbjct: 674 LALNFATQIKVQKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIFLGSYRMPYEDIRN 733
Query: 136 AIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERL 195
I + L ++ L++ LP E K+L + + ++L ++F ++ S V+ L
Sbjct: 734 VILEVNEDMLSEALIQNLVKHLP---EQKILNELAELKNEYDDLCEPEQFGVVMSSVKML 790
Query: 196 TQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRG 255
R++ + F F++++ + P + A+ A +K S+ ++LE++L +GNYMNS R
Sbjct: 791 QPRLSSILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSRN 850
Query: 256 A-VYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS-- 312
A GFK+ L + DTKS D+K TLLHFIA +EKY D+ F EL VE A+ VS
Sbjct: 851 AQSLGFKINFLCKIRDTKSADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVSAQ 910
Query: 313 -----LENVLLDVKELGRGMELIRRECSIHDNSV--LRNFLSTNEGKLDKLQRDAKTAEE 365
L ++ + L R ++ + + HD V + +F T + +KL +
Sbjct: 911 ILKSNLASMEQQIVHLERDIKKFPQAENQHDKFVEKMTSFTKTAREQYEKLSTMHNNMMK 970
Query: 366 AYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKK 425
Y + YF KT FF F + EA +EN R++ EE R +LA+E K
Sbjct: 971 LYENLGEYFIFDSKTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAKLAKE-KA 1029
Query: 426 LDAKTPSQRNKWQ 438
K Q+ K Q
Sbjct: 1030 EQEKLERQKKKKQ 1042
>gb|AAG31306.1|AC079041_8 (AC079041) unknown protein [Arabidopsis thaliana]
Length = 1201
Score = 170 bits (426), Expect = 4e-41
Identities = 130/470 (27%), Positives = 216/470 (45%), Gaps = 59/470 (12%)
Query: 2 PPPPDKCPPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTK---------------FRL 46
PPPP PAPP P + + V PPGL PPP+ K L
Sbjct: 718 PPPPLSKTPAPPPPPLSKTPVPPPPPGLGRGTSSGPPPLGAKGSNAPPPPPPAGRGRASL 777
Query: 47 PVFNWTALK-PNQIPSGTVFSELDDEKILEDKFEELF------KTKAQGPALDL------ 93
+ + P P T L K+ L+ + + + P +D+
Sbjct: 778 GLGRGRGVSVPTAAPKKTALKPLHWSKVTRAAKGSLWADTQKQENQPRAPEIDISELESL 837
Query: 94 ------ICSKNKTAQKAAS-----KVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDL 142
+K T ++ +S KV L++ RA N I L K ++ A+ D
Sbjct: 838 FSAVSDTTAKKSTGRRGSSISKPEKVQLVDLRRANNCEIMLTKIKIPLPDMLSAVLALDS 897
Query: 143 QTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGM 202
L +D VE L++F PT+ E++LLR Y +++ L + +V R+ ++
Sbjct: 898 LALDIDQVENLIKFCPTKEEMELLRNYTGDKEMLGKC----------EQVPRIEAKLRVF 947
Query: 203 AFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNS-SKRGAVYGFK 261
F F ++ L LN I AA+ VK S KL+Q+++ IL LGN +N + RG+ GFK
Sbjct: 948 GFKITFASQVEELKSCLNTINAATKEVKESAKLRQIMQTILTLGNALNQGTARGSAVGFK 1007
Query: 262 LQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVK 321
L SL L DT++ + KMTL+H++ V EK P+L +F ++L +E A+ + L+ + +++
Sbjct: 1008 LDSLLKLSDTRARNNKMTLMHYLCKLVGEKMPELLDFANDLVHLEAASKIELKTLAEEMQ 1067
Query: 322 ELGRGMELIRRE--CSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR------- 372
+G+E + +E S +D ++ F + LD + KT Y+ V R
Sbjct: 1068 AATKGLEKVEQELMASENDGAISLGFRKVLKEFLDMADEEVKTLASLYSEVGRNADSLSH 1127
Query: 373 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQE 422
YFGE P P + F++++ ++ +ENE + + E+ EK+ +E
Sbjct: 1128 YFGEDPARCPFEQVTKILTLFMKTFIKSREENEKQAEAEKKKLEKEAIKE 1177
>ref|NP_031884.1| diaphanous homolog 1 (Drosophila) [Mus musculus]
sp|O08808|DIA1_MOUSE DIAPHANOUS PROTEIN HOMOLOG 1 (P140MDIA)
pir||T31065 diaphanous protein homolog p140mDia - mouse
gb|AAC53280.1| (U96963) p140mDia [Mus musculus]
Length = 1255
Score = 166 bits (417), Expect = 4e-40
Identities = 121/469 (25%), Positives = 220/469 (46%), Gaps = 42/469 (8%)
Query: 1 LPPPPDKCPPAPPLPGAAPSVVLTVPP--------------GLSAIRIKKPP-----PIK 41
LPPPP P AP +P P + + PP GL+ ++ KP P
Sbjct: 708 LPPPPPPFPGAPGIPPPPPGMGVPPPPPFGFGVPAAPVLPFGLTPKKVYKPEVQLRRPNW 767
Query: 42 TKFRLPVFN----WTALKPNQIPSGTVFSELDDEKILEDKFEELFKTKAQGPALDLICSK 97
+KF + WT +K ++ + +F++L + K + K + G K
Sbjct: 768 SKFVAEDLSQDCFWTKVKEDRFENNELFAKLTLAFSAQTKTSKAKKDQEGGE------EK 821
Query: 98 NKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFL 157
+K ++ +L++ A+NL+I L +EI I + L ++ L++ +
Sbjct: 822 KSVQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQM 881
Query: 158 PTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTP 217
P ++K+L + + E ++LA ++F ++ V RL R+ + F F + ++ + P
Sbjct: 882 PEPEQLKMLSELKEE---YDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKP 938
Query: 218 QLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGA-VYGFKLQSLDLLLDTKSTDR 276
++ ++ AA ++ S+ +LE+ L +GNYMN+ R A +GF + L L DTKS D+
Sbjct: 939 EIVSVTAACEELRKSENFSSLLELTLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSADQ 998
Query: 277 KMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSI 336
KMTLLHF+A + +P++ F EL VEKA+ VS EN+ + ++ + + + R+
Sbjct: 999 KMTLLHFLAELCENDHPEVLKFPDELAHVEKASRVSAENLQKSLDQMKKQIADVERDVQN 1058
Query: 337 HDNSV---------LRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFF 387
+ + +F+ + + +KL+ E Y + YF PK FF
Sbjct: 1059 FPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGDYFVFDPKKLSVEEFF 1118
Query: 388 PVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNK 436
F + +A +EN+ R++ EE MR +LA+E + + Q+ +
Sbjct: 1119 MDLHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKRE 1167
Score = 37.1 bits (84), Expect = 0.45
Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 14/68 (20%)
Query: 1 LPPPPD-----KCPPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTALK 55
+PPPP PP PPLPG A + PP A I PPP+ +P
Sbjct: 623 IPPPPQLPGSAAIPPPPPLPGVAS--IPPPPPLPGATAIPPPPPLPGATAIP-------P 673
Query: 56 PNQIPSGT 63
P +P GT
Sbjct: 674 PPPLPGGT 681
Score = 33.2 bits (74), Expect = 6.7
Identities = 19/48 (39%), Positives = 21/48 (43%), Gaps = 10/48 (20%)
Query: 2 PPPPDKC-PPAPPLPGAA---------PSVVLTVPPGLSAIRIKKPPP 39
P PP C PP PPLPG A S + PP L + PPP
Sbjct: 604 PLPPGTCIPPPPPLPGGACIPPPPQLPGSAAIPPPPPLPGVASIPPPP 651
>sp|P48608|DIA_DROME DIAPHANOUS PROTEIN
pir||T13170 diaphanous protein - fruit fly (Drosophila melanogaster)
gb|AAA67715.1| (U11288) diaphanous protein [Drosophila melanogaster]
Length = 1091
Score = 163 bits (409), Expect = 4e-39
Identities = 123/481 (25%), Positives = 235/481 (48%), Gaps = 41/481 (8%)
Query: 2 PPPPDKC-PPAPPLP------GAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPV--FNWT 52
PPPP PP PP+P G P + + P + + P K + P+ NW
Sbjct: 558 PPPPGMGGPPPPPMPGMMRPGGGPPPPPMMMGPMVPVLPHGLKPKKKWDVKNPMKRANWK 617
Query: 53 ALKPNQIPSGTVFSELDDEKILED--------KFEELFKTKAQGPALDLICSKNKTAQKA 104
A+ P ++ + + ++K+ +D KF K Q A+D K T K
Sbjct: 618 AIVPAKMSDKAFWVKCQEDKLAQDDFLAELAVKFSSKPVKKEQKDAVD----KPTTLTKK 673
Query: 105 ASKVTLLEANRAKNLAITLRKAGR--SAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAE 162
+ +L++ A+NLAI L + + S E+I + D L + ++ L+++LP +
Sbjct: 674 NVDLRVLDSKTAQNLAIMLGGSLKHLSYEQIKICLLRCDTDILSSNILQQLIQYLPPPEQ 733
Query: 163 VKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAI 222
+K L++ + + +PL + ++F +++RL+ R+ + F + D +Q + P + A
Sbjct: 734 LKRLQEIKAKGEPLPPI---EQFAATIGEIKRLSPRLHNLNFKLTYADMVQDIKPDIVAG 790
Query: 223 IAASASVKSSQKLKQMLEIILALGNYMNS-SKRGAVYGFKLQSLDLLLDTKSTDRKMTLL 281
AA +++S+K ++LE+IL LGNYMNS SK A +GF++ L L +TK D K TLL
Sbjct: 791 TAACEEIRNSKKFSKILELILLLGNYMNSGSKNEAAFGFEISYLTKLSNTKDADNKQTLL 850
Query: 282 HFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHD--- 338
H++A V++K+PD NF+ +L V KA+ V+++ + ++++ ++ + + +
Sbjct: 851 HYLADLVEKKFPDALNFYDDLSHVNKASRVNMDAIQKAMRQMNSAVKNLETDLQNNKVPQ 910
Query: 339 ------NSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVR 392
+ V+ F ++D L + E+ Y + Y+ P FF
Sbjct: 911 CDDDKFSEVMGKFAEECRQQVDVLGKMQLQMEKLYKDLSEYYAFDPSKYTMEEFFADIKT 970
Query: 393 FIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIAELRRRQAK 452
F +++ A +N + E + +K+ QEA++ A+ Q+ + Q+++ + ++ Q +
Sbjct: 971 FKDAFQAAHNDN---VRVREELEKKRRLQEAREQSAR--EQQERQQRKKAVVDMDAPQTQ 1025
Query: 453 E 453
E
Sbjct: 1026 E 1026
>gb|AAF53922.1| (AE003668) dia gene product [Drosophila melanogaster]
Length = 1091
Score = 162 bits (407), Expect = 6e-39
Identities = 123/481 (25%), Positives = 234/481 (48%), Gaps = 41/481 (8%)
Query: 2 PPPPDKC-PPAPPLP------GAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPV--FNWT 52
PPPP PP PP+P G P + + P + + P K + P+ NW
Sbjct: 558 PPPPGMGGPPPPPMPGMMRPGGGPPPPPMMMGPMVPVLPHGLKPKKKWDVKNPMKRANWK 617
Query: 53 ALKPNQIPSGTVFSELDDEKILED--------KFEELFKTKAQGPALDLICSKNKTAQKA 104
A+ P ++ + + ++K+ +D KF K Q A+D K T K
Sbjct: 618 AIVPAKMSDKAFWVKCQEDKLAQDDFLAELAVKFSSKPVKKEQKDAVD----KPTTLTKK 673
Query: 105 ASKVTLLEANRAKNLAITLRKAGR--SAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAE 162
+ +L++ A+NLAI L + + S E+I + D L + ++ L+++LP
Sbjct: 674 NVDLRVLDSKTAQNLAIMLGGSLKHLSYEQIKICLLRCDTDILSSNILQQLIQYLPPPEH 733
Query: 163 VKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAI 222
+K L++ + + +PL + ++F +++RL+ R+ + F + D +Q + P + A
Sbjct: 734 LKRLQEIKAKGEPLPPI---EQFAATIGEIKRLSPRLHNLNFKLTYADMVQDIKPDIVAG 790
Query: 223 IAASASVKSSQKLKQMLEIILALGNYMNS-SKRGAVYGFKLQSLDLLLDTKSTDRKMTLL 281
AA +++S+K ++LE+IL LGNYMNS SK A +GF++ L L +TK D K TLL
Sbjct: 791 TAACEEIRNSKKFSKILELILLLGNYMNSGSKNEAAFGFEISYLTKLSNTKDADNKQTLL 850
Query: 282 HFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHD--- 338
H++A V++K+PD NF+ +L V KA+ V+++ + ++++ ++ + + +
Sbjct: 851 HYLADLVEKKFPDALNFYDDLSHVNKASRVNMDAIQKAMRQMNSAVKNLETDLQNNKVPQ 910
Query: 339 ------NSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVR 392
+ V+ F ++D L + E+ Y + Y+ P FF
Sbjct: 911 CDDDKFSEVMGKFAEECRQQVDVLGKMQLQMEKLYKDLSEYYAFDPSKYTMEEFFADIKT 970
Query: 393 FIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIAELRRRQAK 452
F +++ A +N + E + +K+ QEA++ A+ Q+ + Q+++ + ++ Q +
Sbjct: 971 FKDAFQAAHNDN---VRVREELEKKRRLQEAREQSAR--EQQERQQRKKAVVDMDAPQTQ 1025
Query: 453 E 453
E
Sbjct: 1026 E 1026
>emb|CAC17664.1| (AL354829) bA218B22.1.1 (novel protein (presumed ortholog of mouse
diaphenous-related formin (DIA2)) (isoform 1)) [Homo
sapiens]
Length = 386
Score = 156 bits (391), Expect = 5e-37
Identities = 89/314 (28%), Positives = 169/314 (53%), Gaps = 11/314 (3%)
Query: 131 EEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFS 190
EEI I D L ++ L++ LP + ++ L Q++ E L ++F+++ S
Sbjct: 11 EEIRMMILEVDETRLAESMIQNLIKHLPDQEQLNSLSQFKSE---YSNLCEPEQFVVVMS 67
Query: 191 KVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMN 250
V+RL R++ + F F++ + + P + A+ A +K S+ ++LE++L +GNYMN
Sbjct: 68 NVKRLRPRLSAILFKLQFEEQVNNIKPDIMAVSTACEEIKKSKSFSKLLELVLLMGNYMN 127
Query: 251 SSKRGA-VYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAA 309
+ R A +GF L SL L DTKS D+K TLLHF+ +EKYPD+ NF +L ++KA+
Sbjct: 128 AGSRNAQTFGFNLSSLCKLKDTKSADQKTTLLHFLVEICEEKYPDILNFVDDLEPLDKAS 187
Query: 310 AVSLENVLLDVKELGRGMELIRREC-------SIHDNSVLRNFLSTNEGKLDKLQRDAKT 362
VS+E + +++++GR ++ + +E +HD V + F+ + + + + L + +
Sbjct: 188 KVSVETLEKNLRQMGRQLQQLEKELETFPPPEDLHDKFVTKIFVISAKEQYETLSKLHEN 247
Query: 363 AEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQE 422
E+ Y +++ Y+ K F F ++ +A +EN +++ EE + ++A+E
Sbjct: 248 MEKLYQSIIGYYAIDVKKVSVEDFLTDLNNFRTTFMQAIKENIKKREAEEKEKRVRIAKE 307
Query: 423 AKKLDAKTPSQRNK 436
+ + Q+ K
Sbjct: 308 LAERERLERQQKKK 321
>pir||T46476 hypothetical protein DKFZp434C0931.1 - human
emb|CAB70890.1| (AL137718) hypothetical protein [Homo sapiens]
Length = 691
Score = 150 bits (376), Expect = 3e-35
Identities = 96/327 (29%), Positives = 165/327 (50%), Gaps = 23/327 (7%)
Query: 3 PPPDKCPPAPPLPGAAP--SVVLTVPPGLSAIRIKKPPPI-------------KTKFRLP 47
PPP PP PPLPG S + PP L + + PP+ K + +
Sbjct: 325 PPPPPPPPPPPLPGMRMPFSGPVPPPPPLGFLGGQNSPPLPILPFGLKPKKEFKPEISMR 384
Query: 48 VFNWTALKPNQIPSGTVFSELDDEKI----LEDKFEELFKTKAQGPALDLICSKNKTAQK 103
NW ++P+++ + ++++ K L K E F + + + + K+ +K
Sbjct: 385 RLNWLKIRPHEMTENCFWIKVNENKYENVDLLCKLENTFCCQQKERREEEDIEEKKSIKK 444
Query: 104 AASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEV 163
++ L++ A+NL+I L EEI I D L ++ L++ LP + ++
Sbjct: 445 KIKELKFLDSKIAQNLSIFLSSFRVPYEEIRMMILEVDETRLAESMIQNLIKHLPDQEQL 504
Query: 164 KLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAII 223
L Q++ E L ++F+++ S V+RL R++ + F F++ + + P + A+
Sbjct: 505 NSLSQFKSE---YSNLCEPEQFVVVMSNVKRLRPRLSAILFKLQFEEQVNNIKPDIMAVS 561
Query: 224 AASASVKSSQKLKQMLEIILALGNYMNSSKRGA-VYGFKLQSLDLLLDTKSTDRKMTLLH 282
A +K S+ ++LE++L +GNYMN+ R A +GF L SL L DTKS D+K TLLH
Sbjct: 562 TACEEIKKSKSFSKLLELVLLMGNYMNAGSRNAQTFGFNLSSLCKLKDTKSADQKTTLLH 621
Query: 283 FIALTVKEKYPDLANFWHELHFVEKAA 309
F+ +EKYPD+ NF +L ++KA+
Sbjct: 622 FLVEICEEKYPDILNFVDDLEPLDKAS 648
>dbj|BAB09942.1| (AB005249) contains similarity to unknown
protein~gb|AAF45601.1~gene_id:MXM12.2 [Arabidopsis
thaliana]
Length = 464
Score = 143 bits (358), Expect = 3e-33
Identities = 122/463 (26%), Positives = 207/463 (44%), Gaps = 51/463 (11%)
Query: 1 LPPPPDKC-------PPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPI-----------KT 42
LPPPP PP PP P PP L R PPP KT
Sbjct: 15 LPPPPPPLMRRRAPLPPPPPPPLMRRRAPPPPPPPLMRRRAPPPPPPPPLPRPCSRPPKT 74
Query: 43 KFRLPVFNWTALKPNQIPSGTVFSELDDEKILEDKFEELFKTKAQGPALDLICSKNKTA- 101
K L +W +K + G+++ EL + D +E A++L S+ +T
Sbjct: 75 KCSLKPLHW--VKKTRALPGSLWDELQRRQECRDIEDEQILC-----AIELSVSEIETIF 127
Query: 102 --------QKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLP-VDFVEC 152
+ KV L++ RA N I L ++ A D L D +E
Sbjct: 128 SLGAKPKPKPEPEKVPLIDLRRATNTEIRLMLLNIRLPDMIAAAMAMDESRLDDFDQIEN 187
Query: 153 LMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNL 212
L+ PT+ ++K L Y ++ E+L +++ KV R+ ++ +F F +
Sbjct: 188 LINLFPTKEDMKFLLTYTGDKGNCEQLF---QYLQEVVKVPRVESKLRVFSFKIQFGTQI 244
Query: 213 QMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSK-RGAVYGFKLQSLDLLLDT 271
LT LNA+ +A +++SQKLK ++E IL LGN +N RG GF+L SL +L +T
Sbjct: 245 TKLTKGLNAVNSACEEIRTSQKLKDIMENILCLGNILNQGTGRGRAVGFRLDSLLILSET 304
Query: 272 KSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIR 331
++ + KMTL+H++ + K DL +F +L +E A+ + L+++ +++ + +G+E ++
Sbjct: 305 RADNSKMTLMHYLCKVLASKASDLLDFHKDLESLESASKIQLKSLAEEIQAITKGLEKLK 364
Query: 332 RECSIHD---------NSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTP 382
+E + + +L+ F+S E ++ + A A+ YFG P
Sbjct: 365 QELTASETDGPVSQVFRKLLKEFISNAETQVATVMALYYPARGNAEALAHYFGYH---YP 421
Query: 383 PSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKK 425
+ FIR +K+A +EN + + E+ K+ E K
Sbjct: 422 FEQVTATLLSFIRLFKKAHEENVKQAELEKKKAAKEAEMEKTK 464
>dbj|BAB09941.1| (AB005249) gene_id:MBK20.23~unknown protein [Arabidopsis thaliana]
Length = 721
Score = 142 bits (355), Expect = 8e-33
Identities = 115/438 (26%), Positives = 216/438 (49%), Gaps = 36/438 (8%)
Query: 1 LPPPPDKCPPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTALKP---- 56
LPPPP PP+P +P PP A K + FR PV ++LKP
Sbjct: 149 LPPPP------PPMPRRSPP---PPPPRFDAFDHKGARMV-CGFRCPVTKRSSLKPLHWV 198
Query: 57 --NQIPSGTVFSELDDEKILEDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEAN 114
+ G+++ EL + EL + + L + +K + K KV L++
Sbjct: 199 KITRALQGSLWDELQIQYGESQTAIELDVPEIE--TLFSVGAKPRPKPKP-EKVPLIDLK 255
Query: 115 RAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQ 174
RA N + L+ ++ A+ D L VD +E L++ PT+ E++LL+ Y ++
Sbjct: 256 RANNTIVNLKILKMPLPDMMAAVMAMDESVLDVDQIENLIQLCPTKEEMELLKNYTGDKA 315
Query: 175 PLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQK 234
L + ++ +L KV R ++ ++F F + LN + +A V+SSQ
Sbjct: 316 TLGK---SEQCLLELMKVPRFEAKLRVLSFKIPFGTKITKFRKMLNVVNSACEEVRSSQM 372
Query: 235 LKQMLEIILALGNYMNS-SKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYP 293
LK++++IIL LGN +N + RG+ GF+L SL +L +T++ + KMTL+H++ + K
Sbjct: 373 LKEIMKIILFLGNTLNQGTARGSAVGFRLDSLLILSETRADNNKMTLMHYLCKVLASKAA 432
Query: 294 DLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHD---------NSVLRN 344
DL +F +L +E ++L+++ ++ + +G+E +++E + + +L++
Sbjct: 433 DLLDFHKDLQSLESTLEINLKSLAEEIHAITKGLEKLKQELTASETDGPVSQVFRKLLKD 492
Query: 345 FLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQEN 404
F+S+ E ++ + +A++ + V + P+V + FIR +K+A QEN
Sbjct: 493 FISSAETQVATVSTLYSSAKKVAHCYVVANKNTCGDRLPAV-SATLLSFIRLFKKAHQEN 551
Query: 405 EARKKQEEVMREKQLAQE 422
KQE++ ++K ++
Sbjct: 552 ---VKQEDLEKKKAATED 566
>dbj|BAB11455.1| (AB010070) contains similarity to unknown
protein~dbj|BAA31641.1~gene_id:MBK20.22 [Arabidopsis
thaliana]
Length = 832
Score = 135 bits (337), Expect = 1e-30
Identities = 89/320 (27%), Positives = 167/320 (51%), Gaps = 18/320 (5%)
Query: 109 TLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQ 168
TL++ RA N I L+K ++ A+ D L VD +E L+RF PT+ E+KLL+
Sbjct: 501 TLIDQRRAFNTMIMLQKVEMPLPDMMAAVLGMDESVLDVDQIENLIRFCPTKEEMKLLKN 560
Query: 169 YERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASAS 228
Y ++ L + +++ L KV + ++ +F +F ++ L LN + +A
Sbjct: 561 YTGDKATLGKC---EQYFLELMKVPGVESKLRVFSFKIHFGTQIKELNKGLNTVNSACEE 617
Query: 229 VKSSQKLKQMLEIILALGNYMNS-SKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALT 287
+++SQKLK++++IIL LGN +N + RG+ GFKL SL L + S + MTL+H++
Sbjct: 618 IRTSQKLKEIMKIILCLGNILNQGTARGSAVGFKLDSLLNLSEKCSANTNMTLMHYLCKV 677
Query: 288 VKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDN-------- 339
+ K DL +F +L +E A+ + L+++ ++ + +G++ + +E + ++
Sbjct: 678 LASKASDLLDFHKDLENLESASKIHLKSLAEEMVAITKGLQKLNQELTASESDGPISEVF 737
Query: 340 -SVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYK 398
+L++F+S E ++ + + +A+V YFGE P P + K
Sbjct: 738 RKLLKDFISVAETQVATVSSLYSSVGGNTDALVHYFGEDPNDYPFEQ-----AAHQENVK 792
Query: 399 EAEQENEARKKQEEVMREKQ 418
+AE E + K+ E+ + K+
Sbjct: 793 QAELEKKKAAKEAEMEKTKK 812
Score = 63.6 bits (152), Expect = 5e-09
Identities = 95/433 (21%), Positives = 167/433 (37%), Gaps = 79/433 (18%)
Query: 1 LPPPPDKCPPAPPLPGAAPSVVLTVP-PGLSAIRIKKPPPIKTKFRLPVFNWTALKPNQI 59
LPPPP APP A +V P P +K+ +K LP W L+ Q+
Sbjct: 100 LPPPPLIFVGAPPPTCALKGIVCCFPCPSKKKSSLKRFNWVKITRALPGSLWDELQIQQV 159
Query: 60 PSGTVFSELDDEKIL------EDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEA 113
G +++DE+IL + E F A P D L++
Sbjct: 160 CHG----DIEDEQILCAIELDVSEIETFFSLGAAKPEKD----------------PLIDL 199
Query: 114 NRAKNLAITLRKAG-RSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERE 172
RA + +TL R ++ AI D L D + L+ PT+ ++LL Y
Sbjct: 200 RRATDTELTLMLLNIRLPADMMAAIMAMDESVLDDDEIRGLINLFPTKENMELLMSYTGG 259
Query: 173 RQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSS 232
+ LE+ FS V T +T A A++ +K+
Sbjct: 260 KWTLEKWEQS------FSSVINFT------------------ITVLPRAKEGATSRIKAE 295
Query: 233 QKLKQMLEIILALGNYMNSSK-RGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEK 291
+K +Y++ + R ++ L + + T+ R + + +
Sbjct: 296 RKR-----------DYVSQQRLRNCIFLVLLLIMIAVQITQFKKRLNVVNSACEEVLASE 344
Query: 292 YPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIH-----DNSVLRNFL 346
DL + +L +E A+ L+++ +++++ R +E + +E + D+ V RN L
Sbjct: 345 ASDLLDVHKDLQSLESASKKQLKSLAEEMQDIIRDLEKLNQELTAAETDGPDSQVFRNTL 404
Query: 347 STNEGKLDKLQRDAKTAEEAYN-------AVVRYFGESPKTTPPSVFFPVFVRFIRSYKE 399
+ + + + KT Y+ A+V YFGE PK P + FIR +++
Sbjct: 405 ---KDFISIAETEVKTVLSLYSVVGKNAVALVNYFGEDPKWCPFEQVTATLLHFIRLFEK 461
Query: 400 AEQENEARKKQEE 412
A +EN + E+
Sbjct: 462 AHEENVKKADLEK 474
>dbj|BAB11443.1| (AB010070) gene_id:MBK20.9~pir||T17454~similar to unknown protein
[Arabidopsis thaliana]
Length = 746
Score = 135 bits (337), Expect = 1e-30
Identities = 94/345 (27%), Positives = 175/345 (50%), Gaps = 35/345 (10%)
Query: 111 LEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYE 170
++ RA + I L K ++ A+ D L VD +E L+RF PT+ E++LL+ Y
Sbjct: 401 IDLRRANDTEIMLTKVNIPLADMMAAVLGMDEYVLDVDQIENLIRFCPTKEEMELLKNYT 460
Query: 171 RERQPL---EELAAED------------------RFMLLFSKVERLTQRMAGMAFLGNFQ 209
++ L E+LA ++ L KV + ++ +F F
Sbjct: 461 GDKATLGKCEQLAKAKAPLKEHFRVINAFPSLTPQYFLEVMKVPGVESKLRAFSFKIQFG 520
Query: 210 DNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNS-SKRGAVYGFKLQSLDLL 268
+ L LNA+ +A V++S+KLK+++ IL +GN +N + G+ GFKL+SL +L
Sbjct: 521 TQIAELNKGLNAVNSACEEVRTSEKLKEIMANILCMGNILNQGTAEGSAVGFKLKSLLIL 580
Query: 269 LDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGME 328
DT + + KMTL+H++ + K DL +F +L +E A+ + L+++ +++ + +G+E
Sbjct: 581 SDTCAPNSKMTLMHYLCKVLASKASDLLDFHKDLESLESASKIQLKSLAEEIQAITKGLE 640
Query: 329 LIRRECSIHDNS---------VLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPK 379
+ ++ + ++ VL++F+S E ++ + + + +A+ YFGE P
Sbjct: 641 KLNKQLTASESDGPVSQVFRKVLKDFISMAETQVATVSSLYSSVGKNADALAHYFGEDPN 700
Query: 380 TTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAK 424
P + FIR +K+A +EN KQ ++ + K A+EA+
Sbjct: 701 HYPFEKVTTTLLSFIRLFKKAHEEN---VKQADLDKNKD-AKEAE 741
Score = 88.9 bits (217), Expect = 1e-16
Identities = 88/388 (22%), Positives = 173/388 (43%), Gaps = 43/388 (11%)
Query: 3 PPPDKCPPAPPLPGAAPSVVLTVPPGLSAIRIKK-------PPPIKTKFRLPVFNWTALK 55
P P + PP PP P P + +PP A P P K + L +W +
Sbjct: 15 PMPGRVPPPPPRP---PPMPRRLPPMFDAFDHTGAGMVWGFPRPAKKRASLKPLHWVKIT 71
Query: 56 PNQIPSGTVFSEL-----DDEKILE---DKFEELFKTKAQGPALDLICSKNKTAQKAASK 107
+ G+++ EL D + +E + E LF +A+ + L ++A+ +
Sbjct: 72 SDL--QGSLWDELQRRHGDSQTAIELDISELETLFFVEAKPEKIRL-----HDLRRASYR 124
Query: 108 VTLLEAN--RAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKL 165
V + + RA N I L ++ A+ D + VD +E L++F PT E++L
Sbjct: 125 VFNVRSYYMRANNKVINL---SMPLPDMMTAVLAMDESVVDVDQIEKLIKFCPTNEEMEL 181
Query: 166 LRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAA 225
L+ Y ++ L + ++++L KV RL ++ +F F + L +LN + +A
Sbjct: 182 LKTYTGDKAALGKY---EQYLLELMKVPRLEAKLRVFSFKTQFGTKITELKERLNVVTSA 238
Query: 226 SASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIA 285
V+SS+KLK++++ I LGN N G KL S + S + +H+
Sbjct: 239 CEEVRSSEKLKEIMKKIPCLGNTSNQGPDRV--GVKLDS------SVSDTHTVKSMHYYC 290
Query: 286 LTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRE--CSIHDNSVLR 343
+ + +L + + +L +E A+ + ++++ +++ + + +E +++E S D
Sbjct: 291 KVLASEASELLDVYKDLQSLESASKIQVKSLAQNIQAIIKRLEKLKQELTASETDGPASE 350
Query: 344 NFLSTNEGKLDKLQRDAKTAEEAYNAVV 371
F +T + + + + T Y+ V+
Sbjct: 351 VFCNTLKDFISIAETEMATVLSLYSVVL 378
>gb|AAF50614.1| (AE003560) CG8633 gene product [Drosophila melanogaster]
Length = 1034
Score = 133 bits (332), Expect = 4e-30
Identities = 123/503 (24%), Positives = 222/503 (43%), Gaps = 78/503 (15%)
Query: 2 PPPPDKCPPAPPLP-----GAAPSVVLTVPPGLSAIRIKKPPP----------------- 39
PPPP P APP P GAAP PP ++ + PPP
Sbjct: 256 PPPPPMAPAAPPPPPPPINGAAPPP--PPPPMINGGALPPPPPPPSMQMASRPRTPDPLA 313
Query: 40 ---IKTKFRLP------------VFNWTALKPNQIPS-----GTVFSELDDEKILE---D 76
+ T LP NW + N++ V S D + + +
Sbjct: 314 AEAVATAILLPQQDTPAPKAKMKTINWGKIPHNKVLGKQNIWSIVASNHQDSPMQDIDWN 373
Query: 77 KFEELF---KTKAQG-PALDLICSK-----------NKTAQKAASKVTLLEANRAKNLAI 121
+ E LF AQG P L S+ ++ ++K ++++TLL+ R+ N+ I
Sbjct: 374 EMEGLFCLQTASAQGSPKLGRDGSQAAAGSNGCDTLDRKSKKESTEITLLDGKRSLNVNI 433
Query: 122 TLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAA 181
L++ S ++I + I + + + + L++ +P E+ +L+ + ++ L
Sbjct: 434 FLKQFRTSNDDIIQLIRQGAHEEIGAERLRGLLKIMPEVDELDMLKGFNGDKA---RLGN 490
Query: 182 EDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEI 241
++F+L +V R+ M F N+ L P +N+++ A + +++ L+++L +
Sbjct: 491 AEKFLLQLLEVPNYKLRIESMLLKEEFAANVAYLEPCINSMLYAGDDLLNNKTLQEVLYM 550
Query: 242 ILALGNYMNSSK-RGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWH 300
++ GN++NS G G KL SL L D ++ M L+HF+AL +++ P+L F
Sbjct: 551 VVVAGNFLNSGGYAGNAAGVKLSSLQKLTDIRANKPGMNLIHFVALQAEKRNPELLQFTG 610
Query: 301 ELHFVEKAAAVSLENVLLDVKELGRGMELIRRE-----CSIHDNSVLRNFLSTNEGKLDK 355
+L +E A+ + E + ++ L + I R+ + + +FL E +L
Sbjct: 611 QLSNLESASKTTSEQINNEINTLDGRIRRIARQIEQPATDVDIKEQMADFLQAAESELSV 670
Query: 356 LQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEE--- 412
LQ K E + +F + T F +F F +K+A +ENE R++QE+
Sbjct: 671 LQAGMKQVESMRLKMSEFFCDDAATFRLEECFKIFHNFCDKFKQAVKENERRQQQEQQAT 730
Query: 413 ---VMREKQLAQEAKKL-DAKTP 431
RE+QLA+ A+++ A TP
Sbjct: 731 LRRKQREEQLARRARQIGQAGTP 753
>sp|O70566|DIA2_MOUSE DIAPHANOUS PROTEIN HOMOLOG 2
emb|CAA75871.1| (Y15910) Dia protein [Mus musculus]
Length = 349
Score = 129 bits (321), Expect = 7e-29
Identities = 96/294 (32%), Positives = 148/294 (49%), Gaps = 14/294 (4%)
Query: 155 RFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQM 214
R LP + ++ L Q + E ++L ++F ++ S V+ L R+ + F F++++
Sbjct: 1 RDLPDQNALRELAQLKSE---YDDLCEPEQFGVVMSTVKMLRPRLTSILFKLTFEEHVNN 57
Query: 215 LTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGA-VYGFKLQSLDLLLDTKS 273
+ P + A+ A +K S+ K++LE+IL +GNYMNS R A GFK+ L + DTKS
Sbjct: 58 IKPSIIAVTLACEELKKSESFKRLLELILLVGNYMNSGSRNAQSLGFKINFLCKIKDTKS 117
Query: 274 TDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS---LENVLLDVKE----LGRG 326
D+K TLLHF+A EKY D+ F EL VE A VS L++ L+ +++ L +
Sbjct: 118 ADQKSTLLHFLAEICDEKYRDILKFPDELEHVESAGKVSAQILKSNLVAMEQSILHLEKN 177
Query: 327 MELIRRECSIHDNSV--LRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPS 384
++ S HD V + +F + DKL + Y ++ YF P T
Sbjct: 178 IKNFPPAESHHDKFVEKMMSFTQNAREQYDKLSTMHSNMLKLYESLGEYFIFDPNTVNME 237
Query: 385 VFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQ 438
FF F + EA +EN RK+ EE R +LA+E K K Q+ K Q
Sbjct: 238 EFFGDLNTFRTLFLEALKENHKRKEMEEKSRRAKLAKE-KAEQEKLERQKKKKQ 290
>sp|Q05859|FOR4_MOUSE FORMIN 4 (LIMB DEFORMITY PROTEIN)
pir||S24407 formin isoform IV - mouse
emb|CAA44244.1| (X62379) formin, isoform IV [Mus musculus]
Length = 1206
Score = 128 bits (318), Expect = 2e-28
Identities = 115/482 (23%), Positives = 210/482 (42%), Gaps = 49/482 (10%)
Query: 2 PPPPDKCPPAPPLPGAAPSVVLTVPPGLS------AIRIKKPPPIKTKFRLPVFNWTALK 55
PPPP PP PP PG AP PPGLS + + + P I+ + WT ++
Sbjct: 726 PPPP---PPPPPPPGLAPPP----PPGLSFGLSSSSSQYPRKPAIEPSCPMKPLYWTRIQ 778
Query: 56 PN---QIPSGTVFSELDDEKILE-DKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLL 111
N Q + T++ L++ I + +FE LF + + K + LL
Sbjct: 779 INDKSQDAAPTLWDSLEEPHIRDTSEFEYLFSKDTTQQKKKPLSEAYEKKNKVKKIIKLL 838
Query: 112 EANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYER 171
+ R++ + I + ++I +AI T D + ++ + L E E+ +R+Y
Sbjct: 839 DGKRSQTVGILISSLHLEMKDIQQAIFTVDDSVVDLETLAALYENRAQEDELTKIRKYYE 898
Query: 172 --ERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASV 229
+ + L+ L ++F+ +++ +R + F F + + L ++ + AS +
Sbjct: 899 TSKEEDLKLLDKPEQFLHELAQIPNFAERAQCIIFRAVFSEGITSLHRKVEIVTRASKGL 958
Query: 230 KSSQKLKQMLEIILALGNYMNSSK--RGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALT 287
+ +K +L +ILA GNYMN RG G+ L+ L L D KS D M L+ ++
Sbjct: 959 LHMKSVKDILALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDNGMNLVDYVVKY 1018
Query: 288 VKEKYPDLANFWHELHFVEK------AAAVSLENVLLDVKELGRGMELIRRECSIHDNSV 341
Y A + + + A+ V E++L D+++L R +E ++ +
Sbjct: 1019 YLRYYDQEAGTDKSVFPLPEPQDFFLASQVKFEDLLKDLRKLKRQLEASEQQMKLVCKES 1078
Query: 342 LRNFLSTNEGKLDKLQRDAK-----------TAEEAYNAVVRYFGESPKT----TPPSVF 386
R +L + KL++ + AK A++++ V YFG PKT PS
Sbjct: 1079 PREYLQPFKDKLEEFFKKAKKEHKMEESHLENAQKSFETTVGYFGMKPKTGEKEVTPSYV 1138
Query: 387 FPVFVRFIRSYK---EAEQENEARKKQEEVMREKQLAQEAKKLDAK----TPSQRNKWQQ 439
F V+ F +K + E +N ++++ + KK++ K T S + + +Q
Sbjct: 1139 FMVWFEFCSDFKTIWKRESKNISKERLKMAQASVSKLTSEKKVETKKINPTASLKERLRQ 1198
Query: 440 QE 441
+E
Sbjct: 1199 KE 1200
>dbj|BAA96907.1| (AB019228) gb|AAD23008.1~gene_id:MCK7.3~strong similarity to unknown
protein [Arabidopsis thaliana]
Length = 1307
Score = 124 bits (309), Expect = 2e-27
Identities = 92/355 (25%), Positives = 164/355 (45%), Gaps = 60/355 (16%)
Query: 107 KVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLL 166
KV L+E RA N I L K +++ ++ + L D VE L++F PT E++LL
Sbjct: 934 KVQLIEHRRAYNCEIMLSKVKVPLQDLTNSVLNLEESALDADQVENLIKFCPTREEMELL 993
Query: 167 RQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAAS 226
+ Y ++ ++L + F L KV R+ ++ +F F +
Sbjct: 994 KGYTGDK---DKLGKCELFFLEMMKVPRVETKLRVFSFKMQF-----------------T 1033
Query: 227 ASVKSSQKLKQMLEIILALGNYMN-SSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIA 285
+ VK+S+K K++++ IL+LGN +N + RGA GFKL SL L +T++ + +MTL+H++
Sbjct: 1034 SQVKNSEKFKRIMQTILSLGNALNQGTARGAAVGFKLDSLPKLSETRARNNRMTLMHYLC 1093
Query: 286 LT---------------------------VKEKYPDLANFWHELHFVEKAAAVSLENVLL 318
+ EK P++ +F EL +E A + L+ +
Sbjct: 1094 KVSFYSLRFCSFVDVLEEERYSLMDSLQILAEKIPEVLDFTKELSSLEPATKIQLKFLAE 1153
Query: 319 DVKELGRGMELIRRECSIHD---------NSVLRNFLSTNEGKLDKLQRDAKTAEEAYNA 369
+++ + +G+E + +E S+ + N +L+ FL E ++ L +
Sbjct: 1154 EMQAINKGLEKVVQELSLSENDGPISHNFNKILKEFLHYAEAEVRSLASLYSGVGRNVDG 1213
Query: 370 VVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAK 424
++ YFGE P P + F+R + A +EN KQ E +K A++ K
Sbjct: 1214 LILYFGEDPAKCPFEQVVSTLLNFVRLFNRAHEEN---GKQLEAEAKKNAAEKEK 1265
>gb|AAG31020.1|AF099933_1 (AF099933) GluR-delta2 specific interacting protein [Mus musculus]
Length = 1024
Score = 120 bits (298), Expect = 4e-26
Identities = 106/422 (25%), Positives = 184/422 (43%), Gaps = 36/422 (8%)
Query: 2 PPPPDKCPPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTALKPNQIPS 61
P PP PP PPLP P + G+ R + + R W ++ ++
Sbjct: 607 PVPP---PPPPPLPPPVPCAPPMLSRGVGHRRSETSHMSVKRLR-----WEQVENSE--- 655
Query: 62 GTVFSELDDEKILEDKFEELFKTKAQGPALDLICSKNKTAQ--------KAASKVTLLEA 113
GT++ +L ++ DK ++ K L+L K + + V +L
Sbjct: 656 GTIWGQLGEDSDY-DKLSDMVKYLD----LELHFGTQKPPKPVPGPEPFRKKEVVEILSH 710
Query: 114 NRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERER 173
+A N +I L + E+ + + + + + L + L+ F P E + +Y+ R
Sbjct: 711 KKAYNTSILLAHLKLTPGELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQ---RYQAFR 767
Query: 174 QPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQ 233
+ L+ D+F+L V R+ + F Q+ + + L + AS +K+S+
Sbjct: 768 EAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSR 827
Query: 234 KLKQMLEIILALGNYMNSS--KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEK 291
KL ++LE +LA+GNY+N K GFK+ L L TK+ D K T LH +A ++ +
Sbjct: 828 KLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQH 887
Query: 292 YPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNS-------VLRN 344
+P+L F +L V AA V+ + D+ +L + I+ C S V+ +
Sbjct: 888 FPELLGFAQDLPTVPLAAKVNQRALTGDLADLHDTVSEIQVACQSMAPSSEDRFAVVMAS 947
Query: 345 FLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQEN 404
FL T + L L + A E + +FGE K T FF +F F+ ++ A +
Sbjct: 948 FLETAQPALRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFSEFMSKFERALSDL 1007
Query: 405 EA 406
+A
Sbjct: 1008 QA 1009
>emb|CAC17665.1| (AL354829) bA218B22.1.2 (novel protein (presumed ortholog of mouse
diaphenous-related formin (DIA2)) (translation of cDNA
DKFZp434C0931 (Em:AL137718)) (isoform 2)) [Homo sapiens]
Length = 230
Score = 117 bits (290), Expect = 3e-25
Identities = 63/180 (35%), Positives = 104/180 (57%), Gaps = 4/180 (2%)
Query: 131 EEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFS 190
EEI I D L ++ L++ LP + ++ L Q++ E L ++F+++ S
Sbjct: 11 EEIRMMILEVDETRLAESMIQNLIKHLPDQEQLNSLSQFKSE---YSNLCEPEQFVVVMS 67
Query: 191 KVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMN 250
V+RL R++ + F F++ + + P + A+ A +K S+ ++LE++L +GNYMN
Sbjct: 68 NVKRLRPRLSAILFKLQFEEQVNNIKPDIMAVSTACEEIKKSKSFSKLLELVLLMGNYMN 127
Query: 251 SSKRGA-VYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAA 309
+ R A +GF L SL L DTKS D+K TLLHF+ +EKYPD+ NF +L ++KA+
Sbjct: 128 AGSRNAQTFGFNLSSLCKLKDTKSADQKTTLLHFLVEICEEKYPDILNFVDDLEPLDKAS 187
>pir||T43168 hypothetical protein cyk-1 - Caenorhabditis elegans (fragment)
gb|AAC17501.1| (AF062008) unknown [Caenorhabditis elegans]
Length = 1018
Score = 116 bits (287), Expect = 7e-25
Identities = 118/489 (24%), Positives = 215/489 (43%), Gaps = 55/489 (11%)
Query: 2 PPPPDKCPPAPPLP------GAAPSVVLTVPPGLSA---------IRIKKPPPIKTKFRL 46
PPPP CPP PP P G P PPG+ A + KK P + R
Sbjct: 345 PPPPGGCPPPPPPPPPGGFKGGPPP---PPPPGMFAPMAPVIPDYLPPKKVPKVDGPMRK 401
Query: 47 PVFNWTA--LKPNQIPSGTVFSELDDEKILEDKFEELFKTK-AQGPALD--LICSKNKTA 101
F W A + P IP + + ++E++ D+ + +TK A PA + + +
Sbjct: 402 --FPWGAHTINPRDIPRESFWVGTNEEQLTSDRMFDRLRTKFATKPAANSGTLGGVLNSK 459
Query: 102 QKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEA 161
+K + + + + L I S E+ AI + + L V F+E L +P E
Sbjct: 460 KKVKTAQVIHDDKLLQKLGILQGSIKMSHSELKLAILEVNEKVLTVGFLEQLRSAMPVEK 519
Query: 162 E-VKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLN 220
E + LR + + EE+ ++F+ +++ L R+ + F F + L L P ++
Sbjct: 520 ELIDKLRAVNKAQ--FEEMPEGEQFVTRLLQIQGLPLRLDLVLFKMRFSEVLNELKPAMS 577
Query: 221 AIIAASASVKSSQKLKQMLEIILALGNYMNSSKR--GAVYGFKLQSLDLLLDTKSTDRKM 278
+++ A V++S+ + L+++LA GN+M + + + Y F ++ L L+DTK D +
Sbjct: 578 SVMEACEEVRASEGFRTFLKLVLATGNFMGGATKNYSSAYAFDMRMLTRLVDTKDVDNRH 637
Query: 279 TLLHFIALTVKEKYPDLANF-WHELHFVEKAAAVSLENVLL-------DVKELGRGMEL- 329
TLLH + +K P A F + H +++ V+ + + ++K+L +++
Sbjct: 638 TLLHHLIEEMKRIDPRRARFALTDFHHCIESSRVNADEIRKTVQLTENNIKKLENCLKVY 697
Query: 330 -IRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFP 388
I+ E + D +R F + + + + ++V+Y+ + K P FF
Sbjct: 698 KIQGERDLFDEK-MRPFHEKAVKEFSTVSSMCGKMKNDWESLVKYYAFNDKKYPMEEFFA 756
Query: 389 VFVRFIRSY----KEAEQENEARKKQE--EVMREKQLAQEAKKLDAKTPSQRNKWQQQEL 442
F Y KE + E EA++K+ E + KQL Q + +R Q+++
Sbjct: 757 DIRTFSEQYSNAWKELDAEAEAKRKEAEFETQKRKQLQQ--------SQQERKPLQERQA 808
Query: 443 IAELRRRQA 451
I + R A
Sbjct: 809 INRVPRTPA 817
>pir||T16038 hypothetical protein F11H8.4 - Caenorhabditis elegans
gb|AAA81161.1| (U40187) similar to PIR:A41724 chicken LD (limb deformity) gene
product and to formin; also P-rich region similar to
collagen [Caenorhabditis elegans]
Length = 1259
Score = 116 bits (287), Expect = 7e-25
Identities = 118/489 (24%), Positives = 215/489 (43%), Gaps = 55/489 (11%)
Query: 2 PPPPDKCPPAPPLP------GAAPSVVLTVPPGLSA---------IRIKKPPPIKTKFRL 46
PPPP CPP PP P G P PPG+ A + KK P + R
Sbjct: 762 PPPPGGCPPPPPPPPPGGFKGGPPP---PPPPGMFAPMAPVIPDYLPPKKVPKVDGPMRK 818
Query: 47 PVFNWTA--LKPNQIPSGTVFSELDDEKILEDKFEELFKTK-AQGPALD--LICSKNKTA 101
F W A + P IP + + ++E++ D+ + +TK A PA + + +
Sbjct: 819 --FPWGAHTINPRDIPRESFWVGTNEEQLTSDRMFDRLRTKFATKPAANSGTLGGVLNSK 876
Query: 102 QKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEA 161
+K + + + + L I S E+ AI + + L V F+E L +P E
Sbjct: 877 KKVKTAQVIHDDKLLQKLGILQGSIKMSHSELKLAILEVNEKVLTVGFLEQLRSAMPVEK 936
Query: 162 E-VKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLN 220
E + LR + + EE+ ++F+ +++ L R+ + F F + L L P ++
Sbjct: 937 ELIDKLRAVNKAQ--FEEMPEGEQFVTRLLQIQGLPLRLDLVLFKMRFSEVLNELKPAMS 994
Query: 221 AIIAASASVKSSQKLKQMLEIILALGNYMNSSKR--GAVYGFKLQSLDLLLDTKSTDRKM 278
+++ A V++S+ + L+++LA GN+M + + + Y F ++ L L+DTK D +
Sbjct: 995 SVMEACEEVRASEGFRTFLKLVLATGNFMGGATKNYSSAYAFDMRMLTRLVDTKDVDNRH 1054
Query: 279 TLLHFIALTVKEKYPDLANF-WHELHFVEKAAAVSLENVLL-------DVKELGRGMEL- 329
TLLH + +K P A F + H +++ V+ + + ++K+L +++
Sbjct: 1055 TLLHHLIEEMKRIDPRRARFALTDFHHCIESSRVNADEIRKTVQLTENNIKKLENCLKVY 1114
Query: 330 -IRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFP 388
I+ E + D +R F + + + + ++V+Y+ + K P FF
Sbjct: 1115 KIQGERDLFDEK-MRPFHEKAVKEFSTVSSMCGKMKNDWESLVKYYAFNDKKYPMEEFFA 1173
Query: 389 VFVRFIRSY----KEAEQENEARKKQE--EVMREKQLAQEAKKLDAKTPSQRNKWQQQEL 442
F Y KE + E EA++K+ E + KQL Q + +R Q+++
Sbjct: 1174 DIRTFSEQYSNAWKELDAEAEAKRKEAEFETQKRKQLQQ--------SQQERKPLQERQA 1225
Query: 443 IAELRRRQA 451
I + R A
Sbjct: 1226 INRVPRTPA 1234
>emb|CAB39108.1| (AL031053) dJ267M20.1 (diaphanous (Drosophila, homolog) 2) [Homo
sapiens]
Length = 222
Score = 115 bits (286), Expect = 9e-25
Identities = 69/214 (32%), Positives = 115/214 (53%), Gaps = 4/214 (1%)
Query: 97 KNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRF 156
K +K ++ +L+ A+NL+I L E+I I + L ++ L++
Sbjct: 11 KTGPTKKKVKELRILDPKTAQNLSIFLGSYRMPYEDIRNVILEVNEDMLSEALIQNLVKH 70
Query: 157 LPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLT 216
LP E K+L + + ++L ++F ++ S V+ L R++ + F F++++ +
Sbjct: 71 LP---EQKILNELAELKNEYDDLCEPEQFGVVMSSVKMLQPRLSSILFKLTFEEHINNIK 127
Query: 217 PQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGA-VYGFKLQSLDLLLDTKSTD 275
P + A+ A +K S+ ++LE++L +GNYMNS R A GFK+ L + DTKS D
Sbjct: 128 PSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSRNAQSLGFKINFLCKIRDTKSAD 187
Query: 276 RKMTLLHFIALTVKEKYPDLANFWHELHFVEKAA 309
+K TLLHFIA +EKY D+ F EL VE A+
Sbjct: 188 QKTTLLHFIADICEEKYRDILKFPEELEHVESAS 221
>gb|AAB64026.1| (AC002333) unknown protein [Arabidopsis thaliana]
Length = 894
Score = 115 bits (284), Expect = 2e-24
Identities = 97/431 (22%), Positives = 186/431 (42%), Gaps = 57/431 (13%)
Query: 2 PPPPDKCPPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTALKPNQIPS 61
PPPP PP PP P+ + PG + KK +K K L +W ++ +
Sbjct: 409 PPPP---PPPPPQVSEVPATMSHSLPGDDSDPEKKVETMKPK--LKTLHWDKVRASS-SR 462
Query: 62 GTVFSELDDE--KILEDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL 119
V+ ++ ++ E+ E LFK +++ Q + + L+ ++ N+
Sbjct: 463 VMVWDQIKSNSFQVNEEMIETLFKVNDPTSR-----TRDGVVQSVSQENRFLDPRKSHNI 517
Query: 120 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPT-EAEVKLLRQYERERQPLEE 178
AI LR +A+E+C A+ + TL + +ECL++ PT E E KL + + +
Sbjct: 518 AILLRALNVTADEVCEALIEGNSDTLGPELLECLLKMAPTKEEEDKLKELKDDDDGSPSK 577
Query: 179 LAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQM 238
+ ++F+ + +R+ M ++ F+ ++ L + + AA+ +K+++ ++
Sbjct: 578 IGPAEKFLKALLNIPFAFKRIDAMLYIVKFESEIEYLNRSFDTLEAATGELKNTRMFLKL 637
Query: 239 LEIILALGNYMN-SSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIA------------ 285
LE +L GN MN + RG + FKL +L L+D K D K TLLHF+
Sbjct: 638 LEAVLKTGNRMNIGTNRGDAHAFKLDTLLKLVDIKGADGKTTLLHFVVQEIIKFEGARVP 697
Query: 286 -----------LTVKEKYPD-----------LANFWHELHFVEKAAAVSLENVLLDVKEL 323
+ + + D ++ +L V+KAAA+ +++ + E+
Sbjct: 698 FTPSQSHIGDNMAEQSAFQDDLELKKLGLQVVSGLSSQLINVKKAAAMDSNSLINETAEI 757
Query: 324 GRGMELIRRECSIHDNSV--------LRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFG 375
RG+ ++ + + +FL+ E ++ +LQ + V YF
Sbjct: 758 ARGIAKVKEVITELKQETGVERFLESMNSFLNKGEKEITELQSHGDNVMKMVKEVTEYFH 817
Query: 376 ESPKTTPPSVF 386
+ +T P +F
Sbjct: 818 GNSETHPFRIF 828
>sp|Q05858|FORM_CHICK FORMIN (LIMB DEFORMITY PROTEIN)
pir||S38780 limb deformity protein - chicken
emb|CAA44555.1| (X62681) limb deformity protein [Gallus gallus]
Length = 1213
Score = 113 bits (280), Expect = 5e-24
Identities = 117/491 (23%), Positives = 216/491 (43%), Gaps = 47/491 (9%)
Query: 2 PPPPDKCPPAPP-LPGAA-------PSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTA 53
PP P PP PP LPG+ P L LS+ + + P I+ + WT
Sbjct: 724 PPLPGLGPPVPPPLPGSGLPPPPPPPGPGLFFNSTLSSSQGPRKPAIEPSRPMKPLYWTR 783
Query: 54 L-----KPNQIPSGTVFSELDDEKILED-KFEELFKTKAQGPALDLICSKNKTAQKAASK 107
+ + IP T++ L++ IL+ +FE LF + + KA
Sbjct: 784 IQLQGSRKTAIP--TLWESLEEPDILDTTEFEYLFSKDTTQEKRKPLSETYEKKTKAKKI 841
Query: 108 VTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLR 167
+ LL+ R++ + I + ++I +AI D + ++ +E L + E++ +
Sbjct: 842 IKLLDGKRSQTVGILISSLHLEMKDIQQAILCVDDSVVDLETLEALYENRAQKDELEKIE 901
Query: 168 QYER--ERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAA 225
QY + + + L+ L ++F+ S++ T+R + F F + + + +++ I
Sbjct: 902 QYYQTSKEEELKLLDKPEQFLYELSQIPNFTERAQCIIFQSVFSEGITSVHRKVDIITRV 961
Query: 226 SASVKSSQKLKQMLEIILALGNYMNSSK--RGAVYGFKLQSLDLLLDTKSTDRKMTLLHF 283
S ++ + +K++L +ILA GNYMN RG GF L+ L L D KS D ++ L+ +
Sbjct: 962 SKALLNMTSVKEILGLILAFGNYMNGGNRTRGQADGFGLEILPKLKDVKSRDNRINLVDY 1021
Query: 284 IALTV-----KEKYPDLANF-WHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIH 337
+ + KE D + F E +A+ V E+++ D+++L R +E ++ +
Sbjct: 1022 VVIYYLRHCDKEAGTDKSIFPLPEPQDFFQASQVKFEDLIKDLRKLKRDLEASEKQMKLV 1081
Query: 338 DNSVLRNFLSTNEGKLDKLQRDAK-----------TAEEAYNAVVRYFGESP----KTTP 382
L + KL++ + AK A++ + V YFG P K
Sbjct: 1082 CRESSEEHLQPFKEKLEEFFQKAKEERKKEESSLENAQKCFEETVGYFGIKPKPGEKEIT 1141
Query: 383 PSVFFPVFVRFIRSYKEA-EQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQE 441
P+ F V+ F +K ++E+++ K+ R K Q KL A+ + K
Sbjct: 1142 PNYVFTVWYEFCSDFKTIWKRESKSISKE----RIKVAQQSVSKLTAEKKVETKKINPTA 1197
Query: 442 LIAE-LRRRQA 451
+ E LR+++A
Sbjct: 1198 SLKERLRQKEA 1208
>pir||S24286 limb deformity protein - chicken
pir||A41724 limb deformity (ld) protein - chicken
Length = 1213
Score = 112 bits (277), Expect = 1e-23
Identities = 117/491 (23%), Positives = 216/491 (43%), Gaps = 47/491 (9%)
Query: 2 PPPPDKCPPAPP-LPGAA-------PSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTA 53
PP P PP PP LPG+ P L LS+ + + P I+ + WT
Sbjct: 724 PPLPGLGPPVPPPLPGSGLPPPPPPPGPGLFFNSTLSSSQGPRKPAIEPSRPMKPLYWTR 783
Query: 54 L-----KPNQIPSGTVFSELDDEKILED-KFEELFKTKAQGPALDLICSKNKTAQKAASK 107
+ + IP T++ L++ IL+ +FE LF + + KA
Sbjct: 784 IQLQGSRKTAIP--TLWESLEEPDILDTTEFEYLFSKDTTQEKRKPLSETYEKKTKAKKI 841
Query: 108 VTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLR 167
+ LL+ R++ + I + ++I +AI D + ++ +E L + E++ +
Sbjct: 842 IKLLDGKRSQTVGILISSLHLEMKDIQQAILCVDDSVVDLETLEGLYENRAQKDELEKIE 901
Query: 168 QYER--ERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAA 225
QY + + + L+ L ++F+ S++ T+R + F F + + + +++ I
Sbjct: 902 QYYQTSKEEELKLLDKPEQFLYELSQIPNFTERAQCIIFQSVFSEGITSVHRKVDIITRV 961
Query: 226 SASVKSSQKLKQMLEIILALGNYMNSSK--RGAVYGFKLQSLDLLLDTKSTDRKMTLLHF 283
S ++ + +K++L +ILA GNYMN RG GF L+ L L D KS D ++ L+ +
Sbjct: 962 SKALLNMTSVKEILGLILAFGNYMNGGNRTRGQADGFGLEILPKLKDVKSRDNRINLVDY 1021
Query: 284 IALTV-----KEKYPDLANF-WHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIH 337
+ + KE D + F E +A+ V E+++ D+++L R +E ++ +
Sbjct: 1022 VVIYYLRHCDKEAGTDKSIFPLPEPQDFFQASQVKFEDLIKDLRKLKRDLEASEKQMKLV 1081
Query: 338 DNSVLRNFLSTNEGKLDKLQRDAK-----------TAEEAYNAVVRYFGESP----KTTP 382
L + KL++ + AK A++ + V YFG P K
Sbjct: 1082 CRESSEEHLQPFKEKLEEFFQKAKEERKKEESSLENAQKCFEETVGYFGIKPKPGEKEIT 1141
Query: 383 PSVFFPVFVRFIRSYKEA-EQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQE 441
P+ F V+ F +K ++E+++ K+ R K Q KL A+ + K
Sbjct: 1142 PNYVFTVWYEFCSDFKTIWKRESKSISKE----RIKVAQQSVSKLTAEKKVETKKINPTA 1197
Query: 442 LIAE-LRRRQA 451
+ E LR+++A
Sbjct: 1198 SLKERLRQKEA 1208
>gb|AAF51054.1| (AE003578) capu gene product [Drosophila melanogaster]
Length = 1059
Score = 111 bits (274), Expect = 2e-23
Identities = 112/465 (24%), Positives = 198/465 (42%), Gaps = 67/465 (14%)
Query: 9 PPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTALKPNQIPSGT--VFS 66
PPAP P A S T G S +PP A P P T +++
Sbjct: 608 PPAPRPPSVANSTDSTENSGSSP---DEPPAANG----------ADAPPTAPPATKEIWT 654
Query: 67 ELDDEKILE-DKFEELFKTKAQGPALDLICSKNKTAQ-KAASKVTLLEANRAKNLAITLR 124
E+++ + D+F ELF +A P SK K + K A + +L+ R++N+ I R
Sbjct: 655 EIEETPLDNIDEFTELFSRQAIAPV-----SKPKELKVKRAKSIKVLDPERSRNVGIIWR 709
Query: 125 KAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDR 184
+ EI AI+ D + ++ ++ + TE E++ +++ PL+ ++
Sbjct: 710 SLHVPSSEIEHAIYHIDTSVVSLEALQHMSNIQATEDELQRIKEAAGGDIPLDH---PEQ 766
Query: 185 FMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILA 244
F+L S + ++R++ + F F++++ +L +L + S + S+ LK + IIL
Sbjct: 767 FLLDISLISMASERISCIVFQAEFEESVTLLFRKLETVSQLSQQLIESEDLKLVFSIILT 826
Query: 245 LGNYMN--SSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIA--------------LTV 288
LGNYMN + +RG GF L L L D KS + TLLHFI L +
Sbjct: 827 LGNYMNGGNRQRGQADGFNLDILGKLKDVKSKESHTTLLHFIVRTYIAQRRKEGVHPLEI 886
Query: 289 KEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRG-----------MELIRRECSIH 337
+ P+ A+ VE+AA + E V + +L + + R E
Sbjct: 887 RLPIPEPAD-------VERAAQMDFEEVQQQIFDLNKKFLGCKRTTAKVLAASRPEIMEP 939
Query: 338 DNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKT-------TPPSVFFPVF 390
S + F+ + + KL + + + +R++ SPK P FF +
Sbjct: 940 FKSKMEEFVEGADKSMAKLHQSLDECRDLFLETMRFYHFSPKACTLTLAQCTPDQFFEYW 999
Query: 391 VRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRN 435
F +K+ + E E+M++ + AQ + + T +++
Sbjct: 1000 TNFTNDFKDI-WKKEITSLLNELMKKSKQAQIESRRNVSTKVEKS 1043
>pir||T13286 cappuccino gene protein - fruit fly (Drosophila melanogaster)
gb|AAC46925.1| (U34258) cappuccino [Drosophila melanogaster]
prf||2123320A cappuccino gene [Drosophila melanogaster]
Length = 1058
Score = 111 bits (274), Expect = 2e-23
Identities = 112/465 (24%), Positives = 198/465 (42%), Gaps = 67/465 (14%)
Query: 9 PPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTALKPNQIPSGT--VFS 66
PPAP P A S T G S +PP A P P T +++
Sbjct: 607 PPAPRPPSVANSTDSTENSGSSP---DEPPAANG----------ADAPPTAPPATKEIWT 653
Query: 67 ELDDEKILE-DKFEELFKTKAQGPALDLICSKNKTAQ-KAASKVTLLEANRAKNLAITLR 124
E+++ + D+F ELF +A P SK K + K A + +L+ R++N+ I R
Sbjct: 654 EIEETPLDNIDEFTELFSRQAIAPV-----SKPKELKVKRAKSIKVLDPERSRNVGIIWR 708
Query: 125 KAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDR 184
+ EI AI+ D + ++ ++ + TE E++ +++ PL+ ++
Sbjct: 709 SLHVPSSEIEHAIYHIDTSVVSLEALQHMSNIQATEDELQRIKEAAGGDIPLDH---PEQ 765
Query: 185 FMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILA 244
F+L S + ++R++ + F F++++ +L +L + S + S+ LK + IIL
Sbjct: 766 FLLDISLISMASERISCIVFQAEFEESVTLLFRKLETVSQLSQQLIESEDLKLVFSIILT 825
Query: 245 LGNYMN--SSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIA--------------LTV 288
LGNYMN + +RG GF L L L D KS + TLLHFI L +
Sbjct: 826 LGNYMNGGNRQRGQADGFNLDILGKLKDVKSKESHTTLLHFIVRTYIAQRRKEGVHPLEI 885
Query: 289 KEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRG-----------MELIRRECSIH 337
+ P+ A+ VE+AA + E V + +L + + R E
Sbjct: 886 RLPIPEPAD-------VERAAQMDFEEVQQQIFDLNKKFLGCKRTTAKVLAASRPEIMEP 938
Query: 338 DNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKT-------TPPSVFFPVF 390
S + F+ + + KL + + + +R++ SPK P FF +
Sbjct: 939 FKSKMEEFVEGADKSMAKLHQSLDECRDLFLETMRFYHFSPKACTLTLAQCTPDQFFEYW 998
Query: 391 VRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRN 435
F +K+ + E E+M++ + AQ + + T +++
Sbjct: 999 TNFTNDFKDI-WKKEITSLLNELMKKSKQAQIESRRNVSTKVEKS 1042
>dbj|BAA22512.1| (D38411) 'Ppf3p' [Saccharomyces cerevisiae]
Length = 1953
Score = 109 bits (271), Expect = 5e-23
Identities = 120/501 (23%), Positives = 207/501 (40%), Gaps = 78/501 (15%)
Query: 2 PPPP--------DKCPPAPPLPGAAPS----VVLTVPPGLSAIRIK---------KPPPI 40
PPPP + PP PPLP S V+ PP + A +IK + P +
Sbjct: 1288 PPPPMALFGKPKGETPPPPPLPSVLSSSTDGVIPPAPPMMPASQIKSAVTSPLLPQSPSL 1347
Query: 41 KTKF-----RLPVFNWTALKPNQIPSGTVFSELDDEKILEDKFE-----ELFKTKAQGPA 90
K+ +L +W L +++ EK +D +E +L K A
Sbjct: 1348 FEKYPRPHKKLKQLHWEKL---DCTDNSIWGTGKAEKFADDLYEKGVLADLEKAFAAREI 1404
Query: 91 LDLICSKNKTAQKAASKVTLLEANRAKNLAITLRK-AGRSAEEICRAIHTFD---LQTLP 146
L + + QK +T L + ++ I L + S ++ + I D LQT
Sbjct: 1405 KSLASKRKEDLQK----ITFLSRDISQQFGINLHMYSSLSVADLVKKILNCDRDFLQTPS 1460
Query: 147 VDFVECLMRFLPTEAEVKLLRQYER-----------------ERQPLEELAAEDRFMLLF 189
V VE L + E V L R Y E+ P + A+ ++ L
Sbjct: 1461 V--VEFLSKSEIIEVSVNLARNYAPYSTDWEGVRNLEDAKPPEKDPNDLQRADQIYLQLM 1518
Query: 190 SKVERLT-QRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNY 248
+E RM + + +++ L +L + A ++++ S L+ + +ILA+GN+
Sbjct: 1519 VNLESYWGSRMRALTVVTSYEREYNELLAKLRKVDKAVSALQESDNLRNVFNVILAVGNF 1578
Query: 249 MNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKA 308
MN + + A GFKL +L L K T MT L+++ V+ YP +F EL V
Sbjct: 1579 MNDTSKQA-QGFKLSTLQRLTFIKDTTNSMTFLNYVEKIVRLNYPSFNDFLSELEPVLDV 1637
Query: 309 AAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNF-------------LSTNEGKLDK 355
VS+E ++ D K+ + + + R I + S F L K D
Sbjct: 1638 VKVSIEQLVNDCKDFSQSIVNVERSVEIGNLSDSSKFHPLDKVLIKTLPVLPEARKKGDL 1697
Query: 356 LQRDAKTAEEAYNAVVRYFGESPKTTPPSV-FFPVFVRFIRSYKEAEQENEARKKQEEV- 413
L+ + K + +++ +GE + FF F FI YK+A+ +N A +++E +
Sbjct: 1698 LEDEVKLTIMEFESLMHTYGEDSGDKFAKISFFKKFADFINEYKKAQAQNLAAEEEERLY 1757
Query: 414 MREKQLAQEAKKLDAKTPSQR 434
++ K++ +E +K + Q+
Sbjct: 1758 IKHKKIVEEQQKRAQEKEKQK 1778
>ref|NP_014128.1| contains formin homology domains; homologous to BNR1 (BNI1 related
protein); Bni1p [Saccharomyces cerevisiae]
sp|P41832|BNI1_YEAST BNI1 PROTEIN (SYNTHETIC LETHAL 39)
pir||S63244 BNI1 protein - yeast (Saccharomyces cerevisiae)
emb|CAA96179.1| (Z71547) ORF YNL271c [Saccharomyces cerevisiae]
Length = 1953
Score = 109 bits (271), Expect = 5e-23
Identities = 120/501 (23%), Positives = 207/501 (40%), Gaps = 78/501 (15%)
Query: 2 PPPP--------DKCPPAPPLPGAAPS----VVLTVPPGLSAIRIK---------KPPPI 40
PPPP + PP PPLP S V+ PP + A +IK + P +
Sbjct: 1288 PPPPMALFGKPKGETPPPPPLPSVLSSSTDGVIPPAPPMMPASQIKSAVTSPLLPQSPSL 1347
Query: 41 KTKF-----RLPVFNWTALKPNQIPSGTVFSELDDEKILEDKFE-----ELFKTKAQGPA 90
K+ +L +W L +++ EK +D +E +L K A
Sbjct: 1348 FEKYPRPHKKLKQLHWEKL---DCTDNSIWGTGKAEKFADDLYEKGVLADLEKAFAAREI 1404
Query: 91 LDLICSKNKTAQKAASKVTLLEANRAKNLAITLRK-AGRSAEEICRAIHTFD---LQTLP 146
L + + QK +T L + ++ I L + S ++ + I D LQT
Sbjct: 1405 KSLASKRKEDLQK----ITFLSRDISQQFGINLHMYSSLSVADLVKKILNCDRDFLQTPS 1460
Query: 147 VDFVECLMRFLPTEAEVKLLRQYER-----------------ERQPLEELAAEDRFMLLF 189
V VE L + E V L R Y E+ P + A+ ++ L
Sbjct: 1461 V--VEFLSKSEIIEVSVNLARNYAPYSTDWEGVRNLEDAKPPEKDPNDLQRADQIYLQLM 1518
Query: 190 SKVERLT-QRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNY 248
+E RM + + +++ L +L + A ++++ S L+ + +ILA+GN+
Sbjct: 1519 VNLESYWGSRMRALTVVTSYEREYNELLAKLRKVDKAVSALQESDNLRNVFNVILAVGNF 1578
Query: 249 MNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKA 308
MN + + A GFKL +L L K T MT L+++ V+ YP +F EL V
Sbjct: 1579 MNDTSKQA-QGFKLSTLQRLTFIKDTTNSMTFLNYVEKIVRLNYPSFNDFLSELEPVLDV 1637
Query: 309 AAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNF-------------LSTNEGKLDK 355
VS+E ++ D K+ + + + R I + S F L K D
Sbjct: 1638 VKVSIEQLVNDCKDFSQSIVNVERSVEIGNLSDSSKFHPLDKVLIKTLPVLPEARKKGDL 1697
Query: 356 LQRDAKTAEEAYNAVVRYFGESPKTTPPSV-FFPVFVRFIRSYKEAEQENEARKKQEEV- 413
L+ + K + +++ +GE + FF F FI YK+A+ +N A +++E +
Sbjct: 1698 LEDEVKLTIMEFESLMHTYGEDSGDKFAKISFFKKFADFINEYKKAQAQNLAAEEEERLY 1757
Query: 414 MREKQLAQEAKKLDAKTPSQR 434
++ K++ +E +K + Q+
Sbjct: 1758 IKHKKIVEEQQKRAQEKEKQK 1778
>gb|AAA34455.1| (L31766) synthetic lethal 39 [Saccharomyces cerevisiae]
Length = 1953
Score = 109 bits (271), Expect = 5e-23
Identities = 120/501 (23%), Positives = 207/501 (40%), Gaps = 78/501 (15%)
Query: 2 PPPP--------DKCPPAPPLPGAAPS----VVLTVPPGLSAIRIK---------KPPPI 40
PPPP + PP PPLP S V+ PP + A +IK + P +
Sbjct: 1288 PPPPMALFGKPKGETPPPPPLPSVLSSSTDGVIPPAPPMMPASQIKSAVTSPLLPQSPSL 1347
Query: 41 KTKF-----RLPVFNWTALKPNQIPSGTVFSELDDEKILEDKFE-----ELFKTKAQGPA 90
K+ +L +W L +++ EK +D +E +L K A
Sbjct: 1348 FEKYPRPHKKLKQLHWEKL---DCTDNSIWGTGKAEKFADDLYEKGVLADLEKAFAAREI 1404
Query: 91 LDLICSKNKTAQKAASKVTLLEANRAKNLAITLRK-AGRSAEEICRAIHTFD---LQTLP 146
L + + QK +T L + ++ I L + S ++ + I D LQT
Sbjct: 1405 KSLASKRKEDLQK----ITFLSRDISQQFCINLHMYSSLSVADLVKKILNCDRDFLQTPS 1460
Query: 147 VDFVECLMRFLPTEAEVKLLRQYER-----------------ERQPLEELAAEDRFMLLF 189
V VE L + E V L R Y E+ P + A+ ++ L
Sbjct: 1461 V--VEFLSKSEIIEVSVNLARNYAPYSTDWEGVRNLEDAKPPEKDPNDLQRADQIYLQLM 1518
Query: 190 SKVERLT-QRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNY 248
+E RM + + +++ L +L + A ++++ S L+ + +ILA+GN+
Sbjct: 1519 VNLESYWGSRMRALTVVTSYEREYNELLAKLRKVDKAVSALQESDNLRNVFNVILAVGNF 1578
Query: 249 MNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKA 308
MN + + A GFKL +L L K T MT L+++ V+ YP +F EL V
Sbjct: 1579 MNDTSKQA-QGFKLSTLQRLTFIKDTTNSMTFLNYVEKIVRLNYPSFNDFLSELEPVLDV 1637
Query: 309 AAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNF-------------LSTNEGKLDK 355
VS+E ++ D K+ + + + R I + S F L K D
Sbjct: 1638 VKVSIEQLVNDCKDFSQSIVNVERSVEIGNLSDSSKFHPLDKVLIKTLPVLPEARKKGDL 1697
Query: 356 LQRDAKTAEEAYNAVVRYFGESPKTTPPSV-FFPVFVRFIRSYKEAEQENEARKKQEEV- 413
L+ + K + +++ +GE + FF F FI YK+A+ +N A +++E +
Sbjct: 1698 LEDEVKLTIMEFESLMHTYGEDSGDKFAKISFFKKFADFINEYKKAQAQNLAAEEEERLY 1757
Query: 414 MREKQLAQEAKKLDAKTPSQR 434
++ K++ +E +K + Q+
Sbjct: 1758 IKHKKIVEEQQKRAQEKEKQK 1778
>gb|AAF24497.1|AF213696_1 (AF213696) FH protein NFH2 [Nicotiana tabacum]
Length = 835
Score = 108 bits (268), Expect = 1e-22
Identities = 104/431 (24%), Positives = 186/431 (43%), Gaps = 64/431 (14%)
Query: 2 PPPPDKCPPAPPLPGAAPSVVLTV--PPGLSAIRIKKPPPIKT--------------KFR 45
PPPP + PP PP P V +T P L + K ++ K +
Sbjct: 331 PPPPQRPPPPPPPFVHGPQVKVTANESPVLISPMEKNDQNVENHSIEKNEEKSEEILKPK 390
Query: 46 LPVFNWTALKPNQIPSGTVFSELDDE--KILEDKFEELFKTKAQGPALDLICS-KNKTAQ 102
L +W ++ + V+ +L K+ E+ E LF K P L+ + K+
Sbjct: 391 LKTLHWDKVRASS-DCEMVWDQLKSSSFKLNEEMIETLFVVK--NPTLNTSATAKHFVVS 447
Query: 103 KAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAE 162
+ + +L+ +++N+AI LR + EEIC A + + + + +E L++ P++ E
Sbjct: 448 SMSQENRVLDPKKSQNIAILLRVLNGTTEEICEAFLEGNAENIGTELLEILLKMAPSKEE 507
Query: 163 VKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAI 222
+ L++Y ++ P +L ++F+ + +R+ M ++ NF + L +
Sbjct: 508 ERKLKEY-KDDSPF-KLGPAEKFLKAVLDIPFAFKRIDAMLYISNFDYEVDYLGNSFETL 565
Query: 223 IAASASVKSSQKLKQMLEIILALGNYMN-SSKRGAVYGFKLQSLDLLLDTKSTDRKMTLL 281
AA ++SS+ ++LE +L GN MN + RG + FKL +L L+D K D K TLL
Sbjct: 566 EAACEELRSSRMFLKLLEAVLKTGNRMNVGTNRGDAHAFKLDTLLKLVDVKGADGKTTLL 625
Query: 282 HFIALTV---------------------------KEKYPDLANFWHELHFVEKAAAVSLE 314
HF+ + K ++N EL V+K+AA+ E
Sbjct: 626 HFVVQEIIKSEGARLSGGNQNHQQSTTNDDAKCKKLGLQVVSNISSELINVKKSAAMDSE 685
Query: 315 NVLLDVKELGRGM----ELIR--RECSIHDNSVLR------NFLSTNEGKLDKLQRDAKT 362
+ DV +L +G+ E++R + ++S+ R F+ E K+ +LQ
Sbjct: 686 VLHNDVLKLSKGIQNIAEVVRSIEAVGLEESSIKRFSESMNRFMKVAEEKILRLQAQETL 745
Query: 363 AEEAYNAVVRY 373
A + Y
Sbjct: 746 AMSLVKEITEY 756
>dbj|BAB01984.1| (AP002460) contains similarity to human diaphanous
1~gene_id:F1D9.13 [Arabidopsis thaliana]
Length = 294
Score = 108 bits (267), Expect = 2e-22
Identities = 85/303 (28%), Positives = 145/303 (47%), Gaps = 45/303 (14%)
Query: 132 EICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSK 191
++ ++ D + VD V+ L++F PT+ E +LL+ + + E L ++F L K
Sbjct: 11 DLMSSVLALDESVIDVDQVDNLIKFCPTKEEAELLKGFIGNK---ETLGRCEQFFLELLK 67
Query: 192 VERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMN- 250
V R+ ++ +F F + V+ S KLK++++ IL+LGN +N
Sbjct: 68 VPRVETKLRVFSFKIQFH-----------------SQVRGSTKLKRIMQTILSLGNALNH 110
Query: 251 SSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTV-KEKYPDLANFWHELHFVEKAA 309
+ RG+ GF L SL L DT+S + KMTL+H++ V EK P L NF ++
Sbjct: 111 GTARGSAIGFHLDSLLKLTDTRSRNSKMTLMHYLCKGVLAEKLPGLLNFPKDM------- 163
Query: 310 AVSLENVLLDVKELGRGMELIRRE-------CSI--HDNSVLRNFLSTNEGKLDKLQRDA 360
+ L+ + +++ +G+E + +E C I H + L+ FLS EG++ L
Sbjct: 164 -IQLKYLAEEMQATSKGLEKVVQEFTASETDCQISKHFHMNLKEFLSVAEGEVRSLASLY 222
Query: 361 KTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQEN------EARKKQEEVM 414
T + +A+ YFGE P P F+R + + +EN E ++ Q+E
Sbjct: 223 STVGGSADALALYFGEDPARVPFEQVVSTLQNFVRIFVRSHEENCKQVEFEKKRAQKEAE 282
Query: 415 REK 417
EK
Sbjct: 283 NEK 285
>gb|AAF14548.1| (AF174427) formin-like protein AHF1 [Arabidopsis thaliana]
dbj|BAB01320.1| (AB025639) formin-like protein [Arabidopsis thaliana]
Length = 1051
Score = 108 bits (266), Expect = 2e-22
Identities = 112/454 (24%), Positives = 192/454 (41%), Gaps = 88/454 (19%)
Query: 1 LPPPPDKCPPAPPLPGAAPSVVLTVPPGLSAIRIKKPP---PIKTKFRLPVFNWTALK-P 56
+PPPP PP PPLP +T A I +PP P F +P N P
Sbjct: 525 VPPPP---PPPPPLPLWGRRSQVTT----KADTISRPPSLTPPSHPFVIPSENLPVTSSP 577
Query: 57 NQIPSGTVFSELDDE--------------------------------KILEDKFEELFKT 84
+ P SE +E K+ E+ E LF
Sbjct: 578 METPETVCASEAAEETPKPKLKALHWDKVRASSDREMVWDHLRSSSFKLDEEMIETLFVA 637
Query: 85 KAQGPALDLICSKNKTAQKAA-----SKVTLLEANRAKNLAITLRKAGRSAEEICRAIHT 139
K+ L+ ++++T + + +L+ +A+N+AI LR + EE+C A+
Sbjct: 638 KS----LNNKPNQSQTTPRCVLPSPNQENRVLDPKKAQNIAILLRALNVTIEEVCEALLE 693
Query: 140 FDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRM 199
+ TL + +E L++ PT+ E + L+ Y + P+ +L ++F+ + +R+
Sbjct: 694 GNADTLGTELLESLLKMAPTKEEERKLKAY-NDDSPV-KLGHAEKFLKAMLDIPFAFKRV 751
Query: 200 AGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMN-SSKRGAVY 258
M ++ NF+ ++ L + AA +++S+ ++LE +L GN MN + RG +
Sbjct: 752 DAMLYVANFESEVEYLKKSFETLEAACEELRNSRMFLKLLEAVLKTGNRMNVGTNRGDAH 811
Query: 259 GFKLQSLDLLLDTKSTDRKMTLLHFIALTV---------------------KEKYPDLAN 297
FKL +L L+D K D K TLLHF+ + K +++
Sbjct: 812 AFKLDTLLKLVDVKGADGKTTLLHFVVQEIIRAEGTRLSGNNTQTDDIKCRKLGLQVVSS 871
Query: 298 FWHELHFVEKAAAVSLENVLLDVKELGRGM----ELIRRECSIHDNS-------VLRNFL 346
EL V+KAAA+ E + V +L +G+ E I+ + +I + S ++ FL
Sbjct: 872 LCSELSNVKKAAAMDSEVLSSYVSKLSQGIAKINEAIQVQSTITEESNSQRFSESMKTFL 931
Query: 347 STNEGKLDKLQRDAKTAEEAYNAVVRYF-GESPK 379
E ++ ++Q A + YF G S K
Sbjct: 932 KRAEEEIIRVQAQESVALSLVKEITEYFHGNSAK 965
>dbj|BAB09344.1| (AB016879) contains similarity to unknown
protein~gb|AAF64546.1~gene_id:MRB17.15 [Arabidopsis
thaliana]
Length = 900
Score = 105 bits (260), Expect = 1e-21
Identities = 124/511 (24%), Positives = 203/511 (39%), Gaps = 80/511 (15%)
Query: 2 PPPPDKCPPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTALKPNQIPS 61
PPP K P PP P PP A + P K +L F W ++ N S
Sbjct: 404 PPPGPKGPRPPPPMSLGPKAPR--PPSGPADALDDDAP---KTKLKPFFWDKVQANPEHS 458
Query: 62 GTVFSELDDEKIL--EDKFEELFKTKAQGPALDLICSKNKTAQKAASK-------VTLLE 112
V++++ E+ E LF A KNK +K +S V +LE
Sbjct: 459 -MVWNDIRSGSFQFNEEMIESLFGYAA--------ADKNKNDKKGSSGQAALPQFVQILE 509
Query: 113 ANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERE 172
+ +NL+I LR + EE+C A+ + LPV+F++ L++ PT E LR Y E
Sbjct: 510 PKKGQNLSILLRALNATTEEVCDALR--EGNELPVEFIQTLLKMAPTPEEELKLRLYCGE 567
Query: 173 RQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSS 232
+ +L + +RF+ + +R+ + F+ + + + + A ++ S
Sbjct: 568 ---IAQLGSAERFLKAVVDIPFAFKRLEALLFMCTLHEEMAFVKESFQKLEVACKELRGS 624
Query: 233 QKLKQMLEIILALGNYMNSSK-RGAVYGFKLQSLDLLLDTKSTDRKMTLLHFI------- 284
+ ++LE +L GN MN RG FKL +L L D K TD K TLLHF+
Sbjct: 625 RLFLKLLEAVLKTGNRMNDGTFRGGAQAFKLDTLLKLADVKGTDGKTTLLHFVVQEIIRT 684
Query: 285 -----ALTVKE-------KYPDL---------------------ANFWHELHFVEKAAAV 311
A T++E K DL + EL V+K+A +
Sbjct: 685 EGVRAARTIRESQSFSSVKTEDLLVEETSEESEENYRNLGLEKVSGLSSELEHVKKSANI 744
Query: 312 SLENVLLDVKELGRGMELIRRECSIHDNS---------VLRNFLSTNEGKLDKLQRDAKT 362
+ + V ++G + R + S L +F+ EG + + + K
Sbjct: 745 DADGLTGTVLKMGHALSKARDFVNSEMKSSGEESGFREALEDFIQNAEGSIMSILEEEKR 804
Query: 363 AEEAYNAVVRYF-GESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREK-QLA 420
+ YF G++ K +F V I K ++ EAR + + R++ A
Sbjct: 805 IMALVKSTGDYFHGKAGKDEGLRLFVIVRDFLIILDKSCKEVREARGRPVRMARKQGSTA 864
Query: 421 QEAKKLDAKTPSQRNKWQQQELIAELRRRQA 451
+ + +TPS + + I E R Q+
Sbjct: 865 SASSETPRQTPSLDPRQKLFPAITERRVDQS 895
>ref|NP_012107.1| involved in actin filament organization; Bnr1p [Saccharomyces
cerevisiae]
sp|P40450|YIP9_YEAST HYPOTHETICAL 156.9 KD PROTEIN IN FOX3-UBP7 INTERGENIC REGION
pir||S48375 hypothetical protein YIL159w - yeast (Saccharomyces cerevisiae)
emb|CAA86119.1| (Z38059) orf, len: 1375, CAI: 0.15 [Saccharomyces cerevisiae]
Length = 1375
Score = 103 bits (255), Expect = 4e-21
Identities = 113/485 (23%), Positives = 208/485 (42%), Gaps = 58/485 (11%)
Query: 9 PPAPPLP-GAAPSVVLTVPPGLSAIRIKKPPPIKTKFRLPVFNWTALKP----------- 56
PPAPPLP G S +++ P + + KPPP T+ RL +W ++
Sbjct: 845 PPAPPLPNGLLSSSSVSINPTTTDL---KPPP--TEKRLKQIHWDKVEDIKDTLWEDTFQ 899
Query: 57 -----NQIPSGTVFSELDDEKILEDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLL 111
++ + +FS+++D I + K K + + S N + K++ L
Sbjct: 900 RQETIKELQTDGIFSQIED--IFKMKSPTKIANKRNAESSIALSSNNGKSSNELKKISFL 957
Query: 112 EANRAKNLAITLRKAGRSA--EEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQY 169
+ A+ I L + + E + + ++ + V+ ++ + +L +Y
Sbjct: 958 SRDLAQQFGINLHMFSQLSDMEFVMKVLNCDNDIVQNVNILKFFCKEELVNIPKSMLNKY 1017
Query: 170 E-----RERQPLEELAAEDRFMLLFSKVERL--TQRMAGMAFLGNFQDNLQMLTPQLNAI 222
E ++ + + +L DR L R R + L ++ + L +L I
Sbjct: 1018 EPYSQGKDGKAVSDLQRADRIFLELCINLRFYWNARSKSLLTLSTYERDYYDLIFKLQKI 1077
Query: 223 IAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKST-DRKMTLL 281
A + + S K K ++ II +GN+MN + V G KL+SL L +S+ D+ ++ L
Sbjct: 1078 DDAISHLNRSPKFKSLMFIITEIGNHMN---KRIVKGIKLKSLTKLAFVRSSIDQNVSFL 1134
Query: 282 HFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSV 341
HFI ++ KYPD+ F +L +E +SLE+V + E + +E + + + S
Sbjct: 1135 HFIEKVIRIKYPDIYGFVDDLKNIEDLGKISLEHVESECHEFHKKIEDLVTQFQVGKLSK 1194
Query: 342 LRNFLSTNEGKLDKLQ---RDAKTAEEA-----------YNAVVRYFGESPK-TTPPSVF 386
N L + + K++ AKT E N +++Y+GE PK + F
Sbjct: 1195 EEN-LDPRDQIIKKVKFKINRAKTKSELLIGQCKLTLIDLNKLMKYYGEDPKDKESKNEF 1253
Query: 387 FPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIAEL 446
F F+ F+ +K+ +EN +++ E V +++ LD +T S + E E
Sbjct: 1254 FQPFIEFLAMFKKCAKENIEKEEMERVYEQRK-----SLLDMRTSSNKKSNGSDENDGEK 1308
Query: 447 RRRQA 451
R A
Sbjct: 1309 VNRDA 1313
Score = 39.1 bits (89), Expect = 0.12
Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
Query: 1 LPPPPDKCPPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTKFR 45
LPPPP PP PPLP + + P G+S I PPP+ F+
Sbjct: 768 LPPPPPP-PPPPPLPQSLLTEAEAKPDGVSCIAAPAPPPLPDLFK 811
>sp|Q10059|CC12_SCHPO CELL DIVISION CONTROL PROTEIN 12
pir||T38091 cell division control protein 12 - fission yeast
(Schizosaccharomyces pombe)
emb|CAA92232.1| (Z68136) cell division control protein 12. [Schizosaccharomyces
pombe]
Length = 1841
Score = 103 bits (254), Expect = 5e-21
Identities = 132/519 (25%), Positives = 215/519 (40%), Gaps = 52/519 (10%)
Query: 2 PPPPDKCPPAPPLPGAAPSVVLTVPPGLSAIRIKKPPPIKTK--FRLPVFNWTALKPNQI 59
PPPP PP PPL AA V P +S I K KT R P + ++
Sbjct: 945 PPPP---PPPPPLVSAAGGKF--VSPAVSN-NISKDDLHKTTGLTRRPTRRLKQMHWEKL 998
Query: 60 PSGTVFSELDDEKILEDKFEELFKTKAQGPALD--LICSKNKT-AQKAASKVTLLEANRA 116
SG F+ +K E T LD + KT +K ++ + +
Sbjct: 999 NSGLEFTFWTGPSDEANKILETLHTSGVLDELDESFAMKEAKTLVKKTCARTDYMSSELQ 1058
Query: 117 KNLAITLRKAG-RSAEEICRAI-HTFDLQTLPVDFVEC--LMRFLPTEAEVKLLR----- 167
K I K ++ EI R I H D V+F+ ++ +A+++ R
Sbjct: 1059 KLFGIHFHKLSHKNPNEIIRMILHCDDSMNECVEFLSSDKVLNQPKLKADLEPYRIDWAN 1118
Query: 168 --QYERERQPLEELAAEDRFM--LLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAII 223
+ EL+ D L+ QRM + + N + L Q I
Sbjct: 1119 GGDLVNSEKDASELSRWDYLYVRLIVDLGGYWNQRMNALKVKNIIETNYENLVRQTKLIG 1178
Query: 224 AASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHF 283
A+ ++ S+ K +L +IL LGNYMN R A GF + SL L K+ + +LLH
Sbjct: 1179 RAALELRDSKVFKGLLYLILYLGNYMNDYVRQAK-GFAIGSLQRLPLIKNANNTKSLLHI 1237
Query: 284 IALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECS-------- 335
+ +T+++ +P NF EL V +AA +++E + + EL RG + ++ +C
Sbjct: 1238 LDITIRKHFPQFDNFSPELSTVTEAAKLNIEAIEQECSELIRGCQNLQIDCDSGALSDPT 1297
Query: 336 -IHDN----SVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPK-TTPPSVFFPV 389
H + SV+ +L K+D L+ +T N +RYFGE P ++FF
Sbjct: 1298 VFHPDDKILSVILPWLMEGTKKMDFLKEHLRTMNTTLNNAMRYFGEQPNDPNSKNLFFKR 1357
Query: 390 FVRFIRSYKEAEQENEARKKQEEVMREKQL---AQEAKKLDAKTPSQRNKWQQQEL---I 443
FI Y +A +N + ++EE + ++L + + + S+ NK + + +
Sbjct: 1358 VDSFIIDYSKARSDN-LKSEEEEASQHRRLNLVNNHKEHVLERAMSENNKMDNEAMDGFL 1416
Query: 444 AELRRRQAKEHR------PVYEGKDGTIEDIITVLKSVP 476
+LR + + H + GK+ IE T KS P
Sbjct: 1417 DKLRNVKLESHHKPRNRSAITMGKEHLIEAPNTSTKSSP 1455
Database: nr
Number of letters in database: 191,393,013
Number of sequences in database: 605,060
Lambda K H
0.318 0.133 0.379
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 181443545
Number of Sequences: 605060
Number of extensions: 7670381
Number of successful extensions: 62093
Number of sequences better than 10.0: 445
Number of HSP's better than 10.0 without gapping: 202
Number of HSP's successfully gapped in prelim test: 260
Number of HSP's that attempted gapping in prelim test: 55519
Number of HSP's gapped (non-prelim): 3581
length of query: 500
length of database: 191,393,013
effective HSP length: 60
effective length of query: 440
effective length of database: 155,089,413
effective search space: 68239341720
effective search space used: 68239341720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 73 (32.8 bits)
