BLASTP 2.2.4 [Aug-26-2002]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

RID: 1031946181-01195-16369

Query= ORF22_1-150 
         (150 letters)


Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF 
           1,044,513 sequences; 330,426,180 total letters

 
If you have any problems or questions with the results of this search 
please refer to the BLAST FAQs



Results of PSI-Blast iteration 8

Skip to the first new sequence

Taxonomy reports

Legend:
 - means that the alignment score was below the threshold on the previous iteration 
 - means that the alignment was checked on the previous iteration 

Hit list size 
Sequences with E-value BETTER than threshold

                                                                     Score    E
Sequences producing significant alignments:                          (bits) Value


 gi|18148891|dbj|BAB83481.1|  (AB063171) ORF22 [Staphylococcus hom...   168   1e-41 

 gi|21779863|gb|AAM77571.1|AF458067_1  (AF458067) IL-17RD [Homo sa...   147   4e-35 

 gi|21667504|gb|AAM74077.1|AF494208_1  (AF494208) interleukin 17 r...   147   5e-35 

 gi|20799328|gb|AAM28441.1|AF459444_1  (AF459444) transmembrane pr...   145   1e-34 

 gi|14726669|ref|XP_045300.1|  (XM_045300) similar to peptidyl-Pro...   144   2e-34 

 gi|11360138|pir||T42695  hypothetical protein DKFZp434N1928.1 - h...   144   2e-34 

 gi|21667510|gb|AAM74080.1|AF494211_1  (AF494211) interleukin 17 r...   144   2e-34 

 gi|20872095|ref|XP_127630.1|  (XM_127630) similar expression to F...   144   4e-34 

 gi|21263748|sp|Q9NRM6|I17S_HUMAN  Interleukin-17B receptor precur...   144   4e-34 

 gi|18845019|gb|AAL79530.1|AF424804_1  (AF424804) similar expressi...   143   6e-34 

 gi|21667506|gb|AAM74078.1|AF494209_1  (AF494209) interleukin 17 r...   142   8e-34 

 gi|9246433|gb|AAF86051.1|AF208110_1  (AF208110) IL-17 receptor ho...   142   2e-33 

 gi|20872223|ref|XP_127670.1|  (XM_127670) similar to IL-17 recept...   135   2e-31 

 gi|18623501|gb|AAL76112.1|AF364103_1  (AF364103) Sef [Danio rerio]     130   4e-30 

 gi|18765887|gb|AAL78817.1|AF401232_1  (AF401232) FGF signaling an...   130   4e-30 

 gi|21223984|ref|NP_629763.1|  (NC_003888) putative ATP /GTP-bindi...   125   1e-28 

 gi|10437850|dbj|BAB15117.1|  (AK025351) unnamed protein product [...   124   3e-28 

 gi|22651846|gb|AAM97776.1|  (AY124197) Toll-related protein; AeTo...   124   3e-28 

 gi|22651844|gb|AAM97775.1|  (AY124196) Toll-related protein; AeTo...   124   3e-28 

 gi|22651842|gb|AAM97774.1|  (AY124195) Toll-related protein; AeTe...   121   2e-27 

 gi|17226676|gb|AAL37901.1|AF444780_1  (AF444780) Toll [Anopheles ...   120   3e-27 

 gi|21758050|dbj|BAC05236.1|  (AK098107) unnamed protein product [...   120   5e-27 

 gi|466393|gb|AAA28942.1|  (L25390) Toll protein [Drosophila pseud...   120   5e-27 

 gi|21223014|ref|NP_628793.1|  (NC_003888) putative ATP/GTP bindin...   120   6e-27 

 gi|17738225|ref|NP_524518.1|  (NM_079794) Toll [Drosophila melano...   119   7e-27 

 gi|19923427|ref|NP_056339.2|  (NM_015524) chromosome 6 open readi...   119   7e-27 

 gi|10257415|gb|AAG15407.1|AF272151_1  (AF272151) adaptor protein ...   119   7e-27 

 gi|22538428|ref|NP_679211.1|  (NM_147686) chromosome 6 open readi...   119   7e-27 

 gi|22538426|ref|NP_671733.1|  (NM_147200) chromosome 6 open readi...   119   7e-27 

 gi|2842416|emb|CAA15506.1|  (AL008730) dJ487J7.1.1 (putative prot...   119   7e-27 

 gi|10439491|dbj|BAB15507.1|  (AK026602) unnamed protein product [...   119   7e-27 

 gi|21464280|gb|AAM51943.1|  (AY121616) GH03720p [Drosophila melan...   119   7e-27 

 gi|21294921|gb|EAA07066.1|  (AAAB01008848) agCP7198 [Anopheles ga...   119   1e-26 

 gi|21292807|gb|EAA04952.1|  (AAAB01008811) agCP4196 [Anopheles ga...   118   1e-26 

 gi|17229067|ref|NP_485615.1|  (NC_003272) unknown protein [Nostoc...   117   3e-26 

 gi|21292746|gb|EAA04891.1|  (AAAB01008811) agCP4197 [Anopheles ga...   117   3e-26 

 gi|21674286|ref|NP_662351.1|  (NC_002932) TIR domain protein [Chl...   117   4e-26 

 gi|6537248|gb|AAF15574.1|  (AF185639) Toll-related protein [Aedes...   116   7e-26 

 gi|21361425|ref|NP_055154.2|  (NM_014339) interleukin 17 receptor...   114   2e-25 

 gi|2826476|gb|AAB99730.1|  (U58917) IL-17 receptor [Homo sapiens]      114   2e-25 

 gi|6981721|gb|AAF15575.2|AF185640_1  (AF185640) toll-related prot...   113   6e-25 

 gi|6537252|gb|AAF15576.1|AF185641_1  (AF185641) Toll [Anopheles g...   112   2e-24 

 gi|6680411|ref|NP_032385.1|  (NM_008359) interleukin 17 receptor ...   111   2e-24 

 gi|466395|gb|AAA28943.1|  (L25391) Toll protein [Drosophila virilis]   110   6e-24 

 gi|21294894|gb|EAA07039.1|  (AAAB01008848) agCP7266 [Anopheles ga...   108   2e-23 

 gi|21291458|gb|EAA03603.1|  (AAAB01008796) agCP1910 [Anopheles ga...   107   4e-23 

 gi|6425008|gb|AAF08257.1|  (AF185646) Toll protein [Drosophila si...   107   4e-23 

 gi|6537258|gb|AAF15579.1|AF185644_1  (AF185644) Toll-related prot...   107   5e-23 

 gi|8923817|ref|NP_061195.1|  (NM_018725) IL-17B receptor [Homo sa...   105   2e-22 

 gi|17137686|ref|NP_477438.1|  (NM_058090) Tehao-P1; tehao [Drosop...   103   5e-22 

 gi|9246967|gb|AAF86227.1|AF247767_1  (AF247767) Toll-5 [Drosophil...   103   5e-22 

 gi|4809185|gb|AAD30131.1|AF140019_1  (AF140019) Toll like protein...   102   8e-22 

 gi|6537254|gb|AAF15577.1|AF185642_1  (AF185642) Toll-related prot...    94   6e-19 

 gi|10955119|ref|NP_059775.1|  (NC_002377) ymc [Agrobacterium tume...    92   2e-18 

 gi|20140787|sp|Q9DGB6|TL22_CHICK  Toll-like receptor 2 type 2 pre...    91   3e-18 

 gi|21228803|ref|NP_634725.1|  (NC_003901) hypothetical protein [M...    91   3e-18 

 gi|20140688|sp|Q95LA9|TLR2_BOVIN  Toll-like receptor 2 precursor ...    91   4e-18 

 gi|20140785|sp|Q9DD78|TL21_CHICK  Toll-like receptor 2 type 1 pre...    91   4e-18 

 gi|19718734|ref|NP_003255.2|  (NM_003264) toll-like receptor 2; t...    89   2e-17 

 gi|20140689|sp|Q95M53|TLR2_MACFA  Toll-like receptor 2 precursor ...    88   2e-17 

 gi|6601447|gb|AAF18983.1|AF204158_1  (AF204158) cell surface rece...    88   3e-17 

 gi|2459624|gb|AAC34133.1|  (U88878) Toll-like receptor 2 [Homo sa...    88   3e-17 

 gi|1223896|gb|AAC46999.1|  (U42425) DmMstProx [Drosophila melanog...    88   4e-17 

 gi|9246971|gb|AAF86229.1|AF247769_1  (AF247769) Toll-3 [Drosophil...    87   4e-17 

 gi|17226682|gb|AAL37904.1|AF444783_1  (AF444783) Trex [Anopheles ...    87   4e-17 

 gi|6425006|gb|AAF08256.1|  (AF185645) Tehao protein [Drosophila s...    87   5e-17 

 gi|21288059|gb|EAA00380.1|  (AAAB01008986) agCP9368 [Anopheles ga...    87   7e-17 

 gi|7297490|gb|AAF52747.1|  (AE003623) Toll-4 gene product [Drosop...    86   8e-17 

 gi|12836693|dbj|BAB23770.1|  (AK005043) data source:MGD, source k...    86   1e-16 

 gi|21955346|gb|AAH14693.1|  (BC014693) Unknown (protein for MGC:1...    86   1e-16 

 gi|6755813|ref|NP_036035.1|  (NM_011905) toll-like receptor 2 [Mu...    86   1e-16 

 gi|20872493|ref|XP_124093.1|  (XM_124093) toll-like receptor 2 [M...    86   1e-16 

 gi|9246969|gb|AAF86228.1|AF247768_1  (AF247768) Toll-4 [Drosophil...    85   2e-16 

 gi|20140897|sp|Q9R1F8|TLR2_CRIGR  Toll-like receptor 2 precursor        85   2e-16 

 gi|11141768|gb|AAG32060.1|AF310951_1  (AF310951) Toll-like recept...    84   4e-16 

 gi|21429694|gb|AAM50059.1|  (AY101393) toll-like receptor 2 [Oryc...    83   9e-16 

 gi|6537256|gb|AAF15578.1|AF185643_1  (AF185643) Toll-related prot...    79   1e-14 

 gi|11513561|pdb|1FYW|A  Chain A, Crystal Structure Of The Tir Dom...    76   8e-14 

 gi|11513563|pdb|1FYX|A  Chain A, Crystal Structure Of P681h Mutan...    73   7e-13 

 gi|286015|dbj|BAA02801.1|  (D13637) KIAA0012 [Homo sapiens]             67   5e-11 

 gi|7513378|pir||T08664  Toll protein-like receptor DKFZp547I0610....    67   5e-11 

 gi|4507527|ref|NP_003254.1|  (NM_003263) toll-like receptor 1; To...    67   5e-11 

 gi|20140925|sp|Q9Y2C9|TLR6_HUMAN  Toll-like receptor 6 precursor ...    67   5e-11 

 gi|20143971|ref|NP_006059.2|  (NM_006068) toll-like receptor 6 [H...    67   5e-11 

 gi|11513559|pdb|1FYV|A  Chain A, Crystal Structure Of The Tir Dom...    66   1e-10 

 gi|13507603|ref|NP_109607.1|  (NM_030682) toll-like receptor 1 [M...    65   3e-10 

 gi|11385997|gb|AAG35062.1|AF316985_1  (AF316985) toll-like recept...    64   3e-10 

 gi|17226678|gb|AAL37902.1|  (AF444781) Toll6 [Anopheles gambiae]        64   4e-10 

 gi|19527222|ref|NP_598761.1|  (NM_134000) expressed sequence AI42...    64   4e-10 

 gi|466432|gb|AAA29811.1|  (L25392) Toll protein [Schistocerca ame...    64   6e-10 

 gi|2842417|emb|CAA15507.1|  (AL008730) dJ487J7.1.2 (putative prot...    64   6e-10 

 gi|21288058|gb|EAA00379.1|  (AAAB01008986) ebiP8963 [Anopheles ga...    63   1e-09 

 gi|17543896|ref|NP_502736.1|  (NM_070335) Y64G10A.6.p [Caenorhabd...    61   3e-09 

 gi|11596326|gb|AAG38563.1|AF314636_1  (AF314636) toll-like recept...    60   1e-08 

 gi|20140792|sp|Q9EPW9|TLR6_MOUSE  Toll-like receptor 6 precursor        60   1e-08 

 gi|6755815|ref|NP_035734.1|  (NM_011604) toll-like receptor 6 [Mu...    60   1e-08 

 gi|13569930|ref|NP_112218.1|  (NM_030956) toll-like receptor 10 p...    59   1e-08 

 gi|20140920|sp|Q9WV82|TLR4_CRIGR  Toll-like receptor 4 precursor ...    59   2e-08 

 gi|20271365|gb|AAM18617.1|AF497565_1  (AF497565) toll-like recept...    59   2e-08 

 gi|20140908|sp|Q9TTN0|TLR4_PANPA  Toll-like receptor 4 precursor ...    58   2e-08 

Alignments







>gi|18148891|dbj|BAB83481.1|   (AB063171) ORF22 [Staphylococcus hominis]
          Length = 306

 Score =  168 bits (427), Expect = 1e-41
 Identities = 148/148 (100%), Positives = 148/148 (100%)

Query: 1   MKKIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFV 60
           MKKIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFV
Sbjct: 1   MKKIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFV 60

Query: 61  LIICSERYKVNADKRRGGSGYEARLMSDEVLRNEDKDRFIPIILNEKDKKNIPNFLKSKL 120
           LIICSERYKVNADKRRGGSGYEARLMSDEVLRNEDKDRFIPIILNEKDKKNIPNFLKSKL
Sbjct: 61  LIICSERYKVNADKRRGGSGYEARLMSDEVLRNEDKDRFIPIILNEKDKKNIPNFLKSKL 120

Query: 121 WTELYHDEQSMEYNNQLDDLLATIIGHD 148
           WTELYHDEQSMEYNNQLDDLLATIIGHD
Sbjct: 121 WTELYHDEQSMEYNNQLDDLLATIIGHD 148



>gi|21779863|gb|AAM77571.1|AF458067_1   (AF458067) IL-17RD [Homo sapiens]
          Length = 739

 Score =  147 bits (371), Expect = 4e-35
 Identities = 29/159 (18%), Positives = 63/159 (39%), Gaps = 23/159 (14%)

Query: 3   KIFISYAW-DEIEDEKVIK-LAEMLEDYKEFEVSFDKWD--INKGQEVPLFMERGIQQSD 58
           K+F+ Y+  D      V++  A  L+D+   EV+ D W+      +    ++ + I +S 
Sbjct: 357 KVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWVIQKIHESQ 416

Query: 59  FVLIICSERYKVNADKRRGG------------------SGYEARLMSDEVLRNEDKDRFI 100
           F++++CS+  K   DK+                     S    +L   +   +    +FI
Sbjct: 417 FIIVVCSKGMKYFVDKKNYKHKGGGRGSGKGELFLVAVSAIAEKLRQAKQSSSAALSKFI 476

Query: 101 PIILNEKDKKNIPNFLK-SKLWTELYHDEQSMEYNNQLD 138
            +  +   + ++P  L  S  +  + +  Q   + +  D
Sbjct: 477 AVYFDYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRD 515



>gi|21667504|gb|AAM74077.1|AF494208_1   (AF494208) interleukin 17 receptor-like protein long form [Homo
           sapiens]
          Length = 739

 Score =  147 bits (371), Expect = 5e-35
 Identities = 29/159 (18%), Positives = 63/159 (39%), Gaps = 23/159 (14%)

Query: 3   KIFISYAW-DEIEDEKVIK-LAEMLEDYKEFEVSFDKWD--INKGQEVPLFMERGIQQSD 58
           K+F+ Y+  D      V++  A  L+D+   EV+ D W+      +    ++ + I +S 
Sbjct: 357 KVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWVIQKIHESQ 416

Query: 59  FVLIICSERYKVNADKRRGG------------------SGYEARLMSDEVLRNEDKDRFI 100
           F++++CS+  K   DK+                     S    +L   +   +    +FI
Sbjct: 417 FIIVVCSKGMKYFVDKKNYKHKGGGRGSGKGELFLVAVSAIAEKLRQAKQSSSAALSKFI 476

Query: 101 PIILNEKDKKNIPNFLK-SKLWTELYHDEQSMEYNNQLD 138
            +  +   + ++P  L  S  +  + +  Q   + +  D
Sbjct: 477 AVYFDYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRD 515



>gi|20799328|gb|AAM28441.1|AF459444_1   (AF459444) transmembrane protein [Mus musculus]
 gi|21667508|gb|AAM74079.1|AF494210_1   (AF494210) interleukin 17 receptor-like protein long form [Mus
           musculus]
          Length = 738

 Score =  145 bits (366), Expect = 1e-34
 Identities = 32/157 (20%), Positives = 65/157 (41%), Gaps = 23/157 (14%)

Query: 3   KIFISYA-WDEIEDEKVIK-LAEMLEDYKEFEVSFDKWD--INKGQEVPLFMERGIQQSD 58
           K+F+ Y+  D      V++  A  L+D+   EV+ D W+      +    +  + I +S 
Sbjct: 357 KVFLCYSNKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWAIQKIHESQ 416

Query: 59  FVLIICSERYKVNADK----RRGGSGYEAR--------------LMSDEVLRNEDKDRFI 100
           F++++CS+  K   DK     +GGS  EA+              L   +   +    +FI
Sbjct: 417 FIIVVCSKGMKYFVDKKNFRHKGGSRGEAQGEFFLVAVAAIAEKLRQAKQSSSAALRKFI 476

Query: 101 PIILNEKDKKNIPNFLK-SKLWTELYHDEQSMEYNNQ 136
            +  +   + ++P  L  S  +  + H  +   + + 
Sbjct: 477 AVYFDYSCEGDVPCSLDLSTKYKLMDHLPELCAHLHS 513



>gi|14726669|ref|XP_045300.1|   (XM_045300) similar to peptidyl-Pro cis trans isomerase [Homo
           sapiens]
          Length = 526

 Score =  144 bits (365), Expect = 2e-34
 Identities = 29/159 (18%), Positives = 63/159 (39%), Gaps = 23/159 (14%)

Query: 3   KIFISYAW-DEIEDEKVIK-LAEMLEDYKEFEVSFDKWD--INKGQEVPLFMERGIQQSD 58
           K+F+ Y+  D      V++  A  L+D+   EV+ D W+      +    ++ + I +S 
Sbjct: 144 KVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWVIQKIHESQ 203

Query: 59  FVLIICSERYKVNADKRRGG------------------SGYEARLMSDEVLRNEDKDRFI 100
           F++++CS+  K   DK+                     S    +L   +   +    +FI
Sbjct: 204 FIIVVCSKGMKYFVDKKNYKHKGGGRGSGKGELFLVAVSAIAEKLRQAKQSSSAALSKFI 263

Query: 101 PIILNEKDKKNIPNFLK-SKLWTELYHDEQSMEYNNQLD 138
            +  +   + ++P  L  S  +  + +  Q   + +  D
Sbjct: 264 AVYFDYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRD 302



>gi|11360138|pir||T42695   hypothetical protein DKFZp434N1928.1 - human (fragment)
 gi|6453552|emb|CAB61408.1|   (AL133097) hypothetical protein [Homo sapiens]
          Length = 564

 Score =  144 bits (365), Expect = 2e-34
 Identities = 29/159 (18%), Positives = 63/159 (39%), Gaps = 23/159 (14%)

Query: 3   KIFISYAW-DEIEDEKVIK-LAEMLEDYKEFEVSFDKWD--INKGQEVPLFMERGIQQSD 58
           K+F+ Y+  D      V++  A  L+D+   EV+ D W+      +    ++ + I +S 
Sbjct: 182 KVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWVIQKIHESQ 241

Query: 59  FVLIICSERYKVNADKRRGG------------------SGYEARLMSDEVLRNEDKDRFI 100
           F++++CS+  K   DK+                     S    +L   +   +    +FI
Sbjct: 242 FIIVVCSKGMKYFVDKKNYKHKGGGRGSGKGELFLVAVSAIAEKLRQAKQSSSAALSKFI 301

Query: 101 PIILNEKDKKNIPNFLK-SKLWTELYHDEQSMEYNNQLD 138
            +  +   + ++P  L  S  +  + +  Q   + +  D
Sbjct: 302 AVYFDYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRD 340



>gi|21667510|gb|AAM74080.1|AF494211_1   (AF494211) interleukin 17 receptor-like protein short form [Homo
           sapiens]
 gi|21739454|emb|CAD38769.1|   (AL833913) hypothetical protein [Homo sapiens]
          Length = 595

 Score =  144 bits (365), Expect = 2e-34
 Identities = 29/159 (18%), Positives = 63/159 (39%), Gaps = 23/159 (14%)

Query: 3   KIFISYAW-DEIEDEKVIK-LAEMLEDYKEFEVSFDKWD--INKGQEVPLFMERGIQQSD 58
           K+F+ Y+  D      V++  A  L+D+   EV+ D W+      +    ++ + I +S 
Sbjct: 213 KVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWVIQKIHESQ 272

Query: 59  FVLIICSERYKVNADKRRGG------------------SGYEARLMSDEVLRNEDKDRFI 100
           F++++CS+  K   DK+                     S    +L   +   +    +FI
Sbjct: 273 FIIVVCSKGMKYFVDKKNYKHKGGGRGSGKGELFLVAVSAIAEKLRQAKQSSSAALSKFI 332

Query: 101 PIILNEKDKKNIPNFLK-SKLWTELYHDEQSMEYNNQLD 138
            +  +   + ++P  L  S  +  + +  Q   + +  D
Sbjct: 333 AVYFDYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRD 371



>gi|20872095|ref|XP_127630.1|   (XM_127630) similar expression to Fgf genes [Mus musculus]
          Length = 710

 Score =  144 bits (363), Expect = 4e-34
 Identities = 32/157 (20%), Positives = 65/157 (41%), Gaps = 23/157 (14%)

Query: 3   KIFISYA-WDEIEDEKVIK-LAEMLEDYKEFEVSFDKWD--INKGQEVPLFMERGIQQSD 58
           K+F+ Y+  D      V++  A  L+D+   EV+ D W+      +    +  + I +S 
Sbjct: 329 KVFLCYSNKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWAIQKIHESQ 388

Query: 59  FVLIICSERYKVNADK----RRGGSGYEAR--------------LMSDEVLRNEDKDRFI 100
           F++++CS+  K   DK     +GGS  EA+              L   +   +    +FI
Sbjct: 389 FIIVVCSKGMKYFVDKKNFRHKGGSRGEAQGEFFLVAVAAIAEKLRQAKQSSSAALRKFI 448

Query: 101 PIILNEKDKKNIPNFLK-SKLWTELYHDEQSMEYNNQ 136
            +  +   + ++P  L  S  +  + H  +   + + 
Sbjct: 449 AVYFDYSCEGDVPCSLDLSTKYKLMDHLPELCAHLHS 485



>gi|21263748|sp|Q9NRM6|I17S_HUMAN   Interleukin-17B receptor precursor (IL-17B receptor) (IL-17
           receptor homolog 1) (IL-17Rh1) (IL17Rh1) (Cytokine
           receptor CRL4)
 gi|12654319|gb|AAH00980.1|AAH00980   (BC000980) Unknown (protein for MGC:5245) [Homo sapiens]
 gi|13649477|gb|AAK37428.1|AF250309_1   (AF250309) putative cytokine receptor CRL4 precusor [Homo sapiens]
          Length = 502

 Score =  144 bits (363), Expect = 4e-34
 Identities = 20/147 (13%), Positives = 43/147 (28%), Gaps = 15/147 (10%)

Query: 3   KIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWD--INKGQEVPLFMERGIQQSDFV 60
           K+ + Y  +      +    E L+++   EV  +KW            ++    + +D V
Sbjct: 333 KVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQKKAADKV 392

Query: 61  LIICSERYKVNADKRRGGSGYEARLMSDEVL------------RNEDKDRFIPIILNEKD 108
           + + S       D   G S       S ++                   +++ +   E D
Sbjct: 393 VFLLSNDVNSVCDGTCGKSEGSPSENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYFREID 452

Query: 109 KKNIPNFLKS-KLWTELYHDEQSMEYN 134
            K+  N L     +  +          
Sbjct: 453 TKDDYNALSVCPKYHLMKDATAFCAEL 479



>gi|18845019|gb|AAL79530.1|AF424804_1   (AF424804) similar expression to FGF protein [Mus musculus]
          Length = 582

 Score =  143 bits (361), Expect = 6e-34
 Identities = 32/157 (20%), Positives = 65/157 (41%), Gaps = 23/157 (14%)

Query: 3   KIFISYA-WDEIEDEKVIK-LAEMLEDYKEFEVSFDKWD--INKGQEVPLFMERGIQQSD 58
           K+F+ Y+  D      V++  A  L+D+   EV+ D W+      +    +  + I +S 
Sbjct: 201 KVFLCYSNKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWAIQKIHESQ 260

Query: 59  FVLIICSERYKVNADK----RRGGSGYEAR--------------LMSDEVLRNEDKDRFI 100
           F++++CS+  K   DK     +GGS  EA+              L   +   +    +FI
Sbjct: 261 FIIVVCSKGMKYFVDKKNFRHKGGSRGEAQGEFFLVAVAAIAEKLRQAKQSSSAALRKFI 320

Query: 101 PIILNEKDKKNIPNFLK-SKLWTELYHDEQSMEYNNQ 136
            +  +   + ++P  L  S  +  + H  +   + + 
Sbjct: 321 AVYFDYSCEGDVPCSLDLSTKYKLMDHLPELCAHLHS 357



>gi|21667506|gb|AAM74078.1|AF494209_1   (AF494209) interleukin 17 receptor-like protein short form [Mus
           musculus]
          Length = 594

 Score =  142 bits (360), Expect = 8e-34
 Identities = 32/157 (20%), Positives = 65/157 (41%), Gaps = 23/157 (14%)

Query: 3   KIFISYA-WDEIEDEKVIK-LAEMLEDYKEFEVSFDKWD--INKGQEVPLFMERGIQQSD 58
           K+F+ Y+  D      V++  A  L+D+   EV+ D W+      +    +  + I +S 
Sbjct: 213 KVFLCYSNKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWAIQKIHESQ 272

Query: 59  FVLIICSERYKVNADK----RRGGSGYEAR--------------LMSDEVLRNEDKDRFI 100
           F++++CS+  K   DK     +GGS  EA+              L   +   +    +FI
Sbjct: 273 FIIVVCSKGMKYFVDKKNFRHKGGSRGEAQGEFFLVAVAAIAEKLRQAKQSSSAALRKFI 332

Query: 101 PIILNEKDKKNIPNFLK-SKLWTELYHDEQSMEYNNQ 136
            +  +   + ++P  L  S  +  + H  +   + + 
Sbjct: 333 AVYFDYSCEGDVPCSLDLSTKYKLMDHLPELCAHLHS 369



>gi|9246433|gb|AAF86051.1|AF208110_1   (AF208110) IL-17 receptor homolog precursor [Homo sapiens]
          Length = 502

 Score =  142 bits (358), Expect = 2e-33
 Identities = 20/147 (13%), Positives = 43/147 (28%), Gaps = 15/147 (10%)

Query: 3   KIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWD--INKGQEVPLFMERGIQQSDFV 60
           K+ + Y  +      +    E L+++   EV  +KW            ++    + +D V
Sbjct: 333 KVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQKKAADKV 392

Query: 61  LIICSERYKVNADKRRGGSGYEARLMSDEVL------------RNEDKDRFIPIILNEKD 108
           + + S       D   G S       S ++                   +++ +   E D
Sbjct: 393 VFLLSNDVNSVCDGTCGKSEGSPSENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYFREID 452

Query: 109 KKNIPNFLKS-KLWTELYHDEQSMEYN 134
            K+  N L     +  +          
Sbjct: 453 TKDDYNALSVCPKYHFMKDATAFCAEL 479



>gi|20872223|ref|XP_127670.1|   (XM_127670) similar to IL-17 receptor homolog precursor [Mus
           musculus]
 gi|21263743|sp|Q9JIP3|I17S_MOUSE   Interleukin-17B receptor precursor (IL-17B receptor) (IL-17
           receptor homolog 1) (IL-17Rh1) (IL17Rh1) (IL-17ER)
 gi|9246429|gb|AAF86049.1|AF208108_1   (AF208108) IL-17 receptor homolog precursor [Mus musculus]
 gi|20071645|gb|AAH26546.1|   (BC026546) interleukin 17B receptor [Mus musculus]
          Length = 499

 Score =  135 bits (340), Expect = 2e-31
 Identities = 22/147 (14%), Positives = 43/147 (28%), Gaps = 15/147 (10%)

Query: 3   KIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWD--INKGQEVPLFMERGIQQSDFV 60
           K+ + Y  +      V +  + L++Y   EV  +KW            ++    Q +D V
Sbjct: 330 KVLVVYPSEICFHHTVCRFTDFLQNYCRSEVILEKWQKKKIAEMGPVQWLTTQKQAADKV 389

Query: 61  LIICSERYKVNADKRRGGSGYEARLMSD------------EVLRNEDKDRFIPIILNEKD 108
           + +         D   G +   AR  S             +        +++ + L   D
Sbjct: 390 VFLLPSDVPTLCDSACGHNEGSARENSQDLFPLAFNLFCSDFSSQTHLHKYLVVYLGGAD 449

Query: 109 KKNIPNFLKS-KLWTELYHDEQSMEYN 134
            K   N L     +  +          
Sbjct: 450 LKGDYNALSVCPQYHLMKDATAFHTEL 476



>gi|18623501|gb|AAL76112.1|AF364103_1   (AF364103) Sef [Danio rerio]
          Length = 745

 Score =  130 bits (328), Expect = 4e-30
 Identities = 30/168 (17%), Positives = 59/168 (34%), Gaps = 33/168 (19%)

Query: 3   KIFISYAW-DEIEDEKVIK-LAEMLEDYKEFEVSFDKWD--INKGQEVPLFMERGIQQSD 58
           KIFI Y+  D  +   VI+  A  L+D+   EVS D W+      +    ++ R I ++ 
Sbjct: 356 KIFICYSSRDGAKHLAVIQSFAFFLQDFCGCEVSLDLWEHLEICKEGQMSWLSRRIDEAH 415

Query: 59  FVLIICSERYK-VNADKRRGGSGYEARLMSDE---------------------------V 90
           F++ +CS+  K     + R G         +                             
Sbjct: 416 FIITVCSKGLKHFVEKRHRKGKATSKEKNREPSASDSSSSSRDLFIVASAIISEKLKEVH 475

Query: 91  LRNEDKDRFIPIILNEKDKKNIPNFLK-SKLWTELYHDEQSMEYNNQL 137
            ++ D  RF+ +  +   + ++P  L  +  +  +    Q     +  
Sbjct: 476 QKSSDLSRFMSVYFDYSHETDVPTSLSLAPKFKLMDQLPQLFARLHSR 523



>gi|18765887|gb|AAL78817.1|AF401232_1   (AF401232) FGF signaling antagonist Sef [Danio rerio]
          Length = 745

 Score =  130 bits (328), Expect = 4e-30
 Identities = 30/168 (17%), Positives = 59/168 (34%), Gaps = 33/168 (19%)

Query: 3   KIFISYAW-DEIEDEKVIK-LAEMLEDYKEFEVSFDKWD--INKGQEVPLFMERGIQQSD 58
           KIFI Y+  D  +   VI+  A  L+D+   EVS D W+      +    ++ R I ++ 
Sbjct: 356 KIFICYSSRDGAKHLAVIQSFAFFLQDFCGCEVSLDLWEHLEICKEGQMSWLSRRIDEAH 415

Query: 59  FVLIICSERYK-VNADKRRGGSGYEARLMSDE---------------------------V 90
           F++ +CS+  K     + R G         +                             
Sbjct: 416 FIITVCSKGLKHFVEKRHRKGKATSKEKNREPSASDSSSSSRDLFIVASAIISEKLKEVH 475

Query: 91  LRNEDKDRFIPIILNEKDKKNIPNFLK-SKLWTELYHDEQSMEYNNQL 137
            ++ D  RF+ +  +   + ++P  L  +  +  +    Q     +  
Sbjct: 476 QKSSDLSRFMSVYFDYSHETDVPTSLSLAPKFKLMDQLPQLFARLHSR 523



>gi|21223984|ref|NP_629763.1|   (NC_003888) putative ATP /GTP-binding protein [Streptomyces
           coelicolor A3(2)]
 gi|7480482|pir||T35469   probable ATP /GTP-binding protein - Streptomyces coelicolor
 gi|3319757|emb|CAA19923.1|   (AL031035) putative ATP /GTP-binding protein [Streptomyces
           coelicolor A3(2)]
          Length = 886

 Score =  125 bits (315), Expect = 1e-28
 Identities = 31/136 (22%), Positives = 54/136 (38%), Gaps = 13/136 (9%)

Query: 2   KKIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVL 61
           ++ FISYA    +      +   LE      V  D WD   G  +   M+  ++++D V+
Sbjct: 6   QQFFISYA--GTDRAWAEWVGWHLEQA-GHRVILDVWDWRTGDNLVQRMDEALERADAVI 62

Query: 62  IICSERYKVNADKRRGGSGYEARLMSDEVLRNEDKDRFIPIILNEKDKKNIPNFLKSKLW 121
            + S  Y    D+R     + A +          +DR IP+ L      ++P  L +KL 
Sbjct: 63  ALFSTSY--FEDERWTTEEWTAAV--------AHRDRLIPLALEPLTTSDLPRVLAAKLR 112

Query: 122 TELYHDEQSMEYNNQL 137
             L+  ++S       
Sbjct: 113 KNLHGLDESAALTALR 128



>gi|10437850|dbj|BAB15117.1|   (AK025351) unnamed protein product [Homo sapiens]
          Length = 564

 Score =  124 bits (312), Expect = 3e-28
 Identities = 30/130 (23%), Positives = 67/130 (51%), Gaps = 14/130 (10%)

Query: 1   MKKIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKW-DINKGQEVPLFMERGIQQSDF 59
           ++K+FI+Y+ D     +V+K    L     F+ + D + D  +G ++  +MER ++ +  
Sbjct: 400 LRKVFITYSMDTA--MEVVKFVNFLL-VNGFQTAIDIFEDRIRGIDIIKWMERYLRDTVM 456

Query: 60  VLIICSERYK---------VNADKRRGGSGYEARLMSDEVLRNEDKD-RFIPIILNEKDK 109
           +++  S +YK         ++ D+    + Y  R+M  E ++    + RFIP++     K
Sbjct: 457 IIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKK 516

Query: 110 KNIPNFLKSK 119
           +++P +L++ 
Sbjct: 517 EHVPTWLQNT 526



>gi|22651846|gb|AAM97776.1|   (AY124197) Toll-related protein; AeToll1B [Aedes aegypti]
          Length = 1076

 Score =  124 bits (312), Expect = 3e-28
 Identities = 23/124 (18%), Positives = 45/124 (35%), Gaps = 11/124 (8%)

Query: 5   FISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLIIC 64
           FISY+  + +      +  + +    F   +   D   G+ +   M R I +S   +++ 
Sbjct: 856 FISYSHHDEDFVANHLVPTLEQPPMNFRTCWHVRDWTPGELITEQMTRSISESRRTIVVL 915

Query: 65  SERYKVNADKRRGGSGYEARLMSDEVLRNED--KDRFIPIILN-EKDKKNIPNFLKSKLW 121
           S+ +          S +         L +    + R I I+     D + +   LK+ L 
Sbjct: 916 SKGF--------LESVWARMEFRTAHLNSIAERRSRVIVILYEHFGDIEQLDADLKAYLR 967

Query: 122 TELY 125
           T  Y
Sbjct: 968 TNTY 971



>gi|22651844|gb|AAM97775.1|   (AY124196) Toll-related protein; AeToll1 [Aedes aegypti]
          Length = 1124

 Score =  124 bits (312), Expect = 3e-28
 Identities = 22/124 (17%), Positives = 48/124 (37%), Gaps = 11/124 (8%)

Query: 5    FISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLIIC 64
            FISY+  + E      +  + ++   F+  +   D   G+ +P  + + ++ S   +++ 
Sbjct: 894  FISYSHKDEEFITEHLVPTLEKEPMNFKTCWHVRDWMPGELIPTQIAKSVEDSRRTIVVL 953

Query: 65   SERYKVNADKRRGGSGYEARLMSDEVLRN--EDKDRFIPIIL-NEKDKKNIPNFLKSKLW 121
            S  +          S +         L +  E + R I II  +    +++   LK+ L 
Sbjct: 954  STNF--------LESVWGRMEFRTAHLTSMEEKRARVIVIIYGDIGSIEDLDPELKAYLK 1005

Query: 122  TELY 125
               Y
Sbjct: 1006 MNTY 1009



>gi|22651842|gb|AAM97774.1|   (AY124195) Toll-related protein; AeTehao [Aedes aegypti]
          Length = 1007

 Score =  121 bits (304), Expect = 2e-27
 Identities = 23/124 (18%), Positives = 51/124 (40%), Gaps = 11/124 (8%)

Query: 5   FISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLIIC 64
           FISY+  + E      + ++  D   F+  +   D   G+ +   + + I  S   +I+ 
Sbjct: 846 FISYSHLDEEFIVDELIPKLENDPMNFKTCWHVRDFMPGEMIMTQIVKSIDASRRTVIVL 905

Query: 65  SERYKVNADKRRGGSGYEARLMSDEVLRNEDKDRFIPIILNEKDKKNIPN---FLKSKLW 121
           S+ +          S +  +      +++ + +R   I++  +D  +I +    LK+ L 
Sbjct: 906 SKNF--------LESSWAKQEFRQAHVQSMEDNRVRVIVVIYEDIGDIDSLDGELKAYLK 957

Query: 122 TELY 125
           T  Y
Sbjct: 958 TNTY 961



>gi|17226676|gb|AAL37901.1|AF444780_1   (AF444780) Toll [Anopheles gambiae]
          Length = 1152

 Score =  120 bits (303), Expect = 3e-27
 Identities = 23/124 (18%), Positives = 47/124 (37%), Gaps = 11/124 (8%)

Query: 5    FISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLIIC 64
            F+SY+  +        +  +  D   F++ +   D   G+ +   +   ++QS   +I+ 
Sbjct: 900  FVSYSHKDEAFITEHLVPTLERDPMNFKLCWHVRDWTPGEMISSQISSSVEQSRRTIIVL 959

Query: 65   SERYKVNADKRRGGSGYEARLMSDEVLRNEDKDRFIPIILNEKDKKNIPN---FLKSKLW 121
            S  +          S +         L++  + R   II+   D  NI +    L++ L 
Sbjct: 960  SSSF--------LESLWGQLEFRTAHLQSMAERRNRLIIIIYGDIGNIYDLEPELRAYLH 1011

Query: 122  TELY 125
            T  Y
Sbjct: 1012 TNTY 1015



>gi|21758050|dbj|BAC05236.1|   (AK098107) unnamed protein product [Homo sapiens]
          Length = 555

 Score =  120 bits (301), Expect = 5e-27
 Identities = 30/131 (22%), Positives = 66/131 (49%), Gaps = 15/131 (11%)

Query: 1   MKKIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKW-DINKGQEVPLFMERGIQQ-SD 58
           ++K+FI+Y+ D     +V+K    L     F+ + D + D  +G ++  +MER ++  + 
Sbjct: 390 LRKVFITYSMDTA--MEVVKFVNFLL-VNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTV 446

Query: 59  FVLIICSERYK---------VNADKRRGGSGYEARLMSDEVLRNEDKD-RFIPIILNEKD 108
            +++  S +YK         ++ D+    + Y  R+M  E +     + RFIP++     
Sbjct: 447 MIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFISQGSMNFRFIPVLFPNAK 506

Query: 109 KKNIPNFLKSK 119
           K+++P +L++ 
Sbjct: 507 KEHVPTWLQNT 517



>gi|466393|gb|AAA28942.1|   (L25390) Toll protein [Drosophila pseudoobscura]
          Length = 1100

 Score =  120 bits (301), Expect = 5e-27
 Identities = 26/125 (20%), Positives = 48/125 (37%), Gaps = 13/125 (10%)

Query: 5   FISYAWDEIEDEKVIKLAEMLED-YKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLII 63
           FISY+  +    +   L   LE   ++F++   + D   G  +P  + R +  S   +I+
Sbjct: 864 FISYSHKDQSFIE-QYLVPQLEHGPQKFQLCVHERDWLVGGFIPENIVRSVADSRRTIIV 922

Query: 64  CSERYKVNADKRRGGSGYEARLMSDEVLR--NEDKDRFIPIIL-NEKDKKNIPNFLKSKL 120
            S+ +          S +             NE + R I +I  +  D + +   LK+ L
Sbjct: 923 LSQNF--------IESEWARMEFRAAHRSALNEGRARIIVVIYSDIGDVEKLDEELKAYL 974

Query: 121 WTELY 125
               Y
Sbjct: 975 KMNTY 979



>gi|21223014|ref|NP_628793.1|   (NC_003888) putative ATP/GTP binding protein [Streptomyces
           coelicolor A3(2)]
 gi|7248326|emb|CAB77406.1|   (AL160431) putative ATP/GTP binding protein [Streptomyces
           coelicolor A3(2)]
          Length = 966

 Score =  120 bits (301), Expect = 6e-27
 Identities = 25/136 (18%), Positives = 53/136 (38%), Gaps = 13/136 (9%)

Query: 2   KKIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVL 61
           ++IF+SYA    +      +   L+     +V  D+W    G +    M   + ++D V+
Sbjct: 6   QRIFLSYA--GPDQAWAEWVGWQLQQA-GHQVELDRWHWRTGDDFVQKMNLALGKADAVV 62

Query: 62  IICSERYKVNADKRRGGSGYEARLMSDEVLRNEDKDRFIPIILNEKDKKNIPNFLKSKLW 121
            + S  Y            +     S  V     + R +P+ +   +  +IP  L   L 
Sbjct: 63  ALFSRHYFEP-------KRWTREEWSAAVAL---RGRLVPVAIELLNDDDIPALLAGTLR 112

Query: 122 TELYHDEQSMEYNNQL 137
           T+++  +++   +  L
Sbjct: 113 TDVHGLDEAAATSALL 128



>gi|17738225|ref|NP_524518.1|   (NM_079794) Toll [Drosophila melanogaster]
 gi|135981|sp|P08953|TOLL_DROME   Toll protein precursor
 gi|85155|pir||A29943   Toll protein precursor - fruit fly (Drosophila melanogaster)
 gi|158641|gb|AAA28941.1|   (M19969) toll protein [Drosophila melanogaster]
 gi|7301502|gb|AAF56624.1|   (AE003758) Tl gene product [Drosophila melanogaster]
          Length = 1097

 Score =  119 bits (300), Expect = 7e-27
 Identities = 27/125 (21%), Positives = 48/125 (37%), Gaps = 13/125 (10%)

Query: 5   FISYAWDEIEDEKVIKLAEMLED-YKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLII 63
           FISY+  +    +   L   LE   ++F++   + D   G  +P  + R +  S   +I+
Sbjct: 862 FISYSHKDQSFIE-DYLVPQLEHGPQKFQLCVHERDWLVGGHIPENIMRSVADSRRTIIV 920

Query: 64  CSERYKVNADKRRGGSGYEARLMSDEVLR--NEDKDRFIPIIL-NEKDKKNIPNFLKSKL 120
            S+ +          S +             NE + R I II  +  D + +   LK+ L
Sbjct: 921 LSQNF--------IKSEWARLEFRAAHRSALNEGRSRIIVIIYSDIGDVEKLDEELKAYL 972

Query: 121 WTELY 125
               Y
Sbjct: 973 KMNTY 977



>gi|19923427|ref|NP_056339.2|   (NM_015524) chromosome 6 open reading frame 5; chromosome 6 open
           reading frame 6 [Homo sapiens]
 gi|7688612|gb|AAF67447.1|AF136407_1   (AF136407) unknown [Homo sapiens]
          Length = 565

 Score =  119 bits (300), Expect = 7e-27
 Identities = 30/131 (22%), Positives = 67/131 (50%), Gaps = 15/131 (11%)

Query: 1   MKKIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKW-DINKGQEVPLFMERGIQQ-SD 58
           ++K+FI+Y+ D     +V+K    L     F+ + D + D  +G ++  +MER ++  + 
Sbjct: 400 LRKVFITYSMDTA--MEVVKFVNFLL-VNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTV 456

Query: 59  FVLIICSERYK---------VNADKRRGGSGYEARLMSDEVLRNEDKD-RFIPIILNEKD 108
            +++  S +YK         ++ D+    + Y  R+M  E ++    + RFIP++     
Sbjct: 457 MIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAK 516

Query: 109 KKNIPNFLKSK 119
           K+++P +L++ 
Sbjct: 517 KEHVPTWLQNT 527



>gi|10257415|gb|AAG15407.1|AF272151_1   (AF272151) adaptor protein CIKS [Homo sapiens]
          Length = 574

 Score =  119 bits (300), Expect = 7e-27
 Identities = 30/131 (22%), Positives = 67/131 (50%), Gaps = 15/131 (11%)

Query: 1   MKKIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKW-DINKGQEVPLFMERGIQQ-SD 58
           ++K+FI+Y+ D     +V+K    L     F+ + D + D  +G ++  +MER ++  + 
Sbjct: 409 LRKVFITYSMDTA--MEVVKFVNFLL-VNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTV 465

Query: 59  FVLIICSERYK---------VNADKRRGGSGYEARLMSDEVLRNEDKD-RFIPIILNEKD 108
            +++  S +YK         ++ D+    + Y  R+M  E ++    + RFIP++     
Sbjct: 466 MIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAK 525

Query: 109 KKNIPNFLKSK 119
           K+++P +L++ 
Sbjct: 526 KEHVPTWLQNT 536



>gi|22538428|ref|NP_679211.1|   (NM_147686) chromosome 6 open reading frame 4 isoform 2; chromosome
           6 open reading frame 6; chromosome 6 open reading frame
           5; connection to IKK and SAPK/JNK; NFkB-activating
           protein ACT1 [Homo sapiens]
 gi|7512888|pir||T08794   hypothetical protein DKFZp586G0522.1 - human
 gi|4886511|emb|CAB43390.1|   (AL050289) hypothetical protein [Homo sapiens]
 gi|7688610|gb|AAF67446.1|AF136406_1   (AF136406) unknown [Homo sapiens]
 gi|12803951|gb|AAH02823.1|AAH02823   (BC002823) DKFZP586G0522 protein [Homo sapiens]
          Length = 565

 Score =  119 bits (300), Expect = 7e-27
 Identities = 30/131 (22%), Positives = 67/131 (50%), Gaps = 15/131 (11%)

Query: 1   MKKIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKW-DINKGQEVPLFMERGIQQ-SD 58
           ++K+FI+Y+ D     +V+K    L     F+ + D + D  +G ++  +MER ++  + 
Sbjct: 400 LRKVFITYSMDTA--MEVVKFVNFLL-VNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTV 456

Query: 59  FVLIICSERYK---------VNADKRRGGSGYEARLMSDEVLRNEDKD-RFIPIILNEKD 108
            +++  S +YK         ++ D+    + Y  R+M  E ++    + RFIP++     
Sbjct: 457 MIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAK 516

Query: 109 KKNIPNFLKSK 119
           K+++P +L++ 
Sbjct: 517 KEHVPTWLQNT 527



>gi|22538426|ref|NP_671733.1|   (NM_147200) chromosome 6 open reading frame 4 isoform 1; chromosome
           6 open reading frame 6; chromosome 6 open reading frame
           5; connection to IKK and SAPK/JNK; NFkB-activating
           protein ACT1 [Homo sapiens]
 gi|13626146|sp|O43734|CIKS_HUMAN   Adapter protein CIKS (Connection to IKK and SAPK/JNK) (Nuclear
           factor NF-kappa-B activator 1) (ACT1)
          Length = 574

 Score =  119 bits (300), Expect = 7e-27
 Identities = 30/131 (22%), Positives = 67/131 (50%), Gaps = 15/131 (11%)

Query: 1   MKKIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKW-DINKGQEVPLFMERGIQQ-SD 58
           ++K+FI+Y+ D     +V+K    L     F+ + D + D  +G ++  +MER ++  + 
Sbjct: 409 LRKVFITYSMDTA--MEVVKFVNFLL-VNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTV 465

Query: 59  FVLIICSERYK---------VNADKRRGGSGYEARLMSDEVLRNEDKD-RFIPIILNEKD 108
            +++  S +YK         ++ D+    + Y  R+M  E ++    + RFIP++     
Sbjct: 466 MIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAK 525

Query: 109 KKNIPNFLKSK 119
           K+++P +L++ 
Sbjct: 526 KEHVPTWLQNT 536



>gi|2842416|emb|CAA15506.1|   (AL008730) dJ487J7.1.1 (putative protein dJ487J7.1 isoform 1) [Homo
           sapiens]
 gi|7688608|gb|AAF67445.1|AF136405_1   (AF136405) unknown [Homo sapiens]
 gi|10242290|gb|AAG15367.1|AF274303_1   (AF274303) NFkB-activating protein ACT1 [Homo sapiens]
          Length = 574

 Score =  119 bits (300), Expect = 7e-27
 Identities = 30/131 (22%), Positives = 67/131 (50%), Gaps = 15/131 (11%)

Query: 1   MKKIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKW-DINKGQEVPLFMERGIQQ-SD 58
           ++K+FI+Y+ D     +V+K    L     F+ + D + D  +G ++  +MER ++  + 
Sbjct: 409 LRKVFITYSMDTA--MEVVKFVNFLL-VNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTV 465

Query: 59  FVLIICSERYK---------VNADKRRGGSGYEARLMSDEVLRNEDKD-RFIPIILNEKD 108
            +++  S +YK         ++ D+    + Y  R+M  E ++    + RFIP++     
Sbjct: 466 MIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAK 525

Query: 109 KKNIPNFLKSK 119
           K+++P +L++ 
Sbjct: 526 KEHVPTWLQNT 536



>gi|10439491|dbj|BAB15507.1|   (AK026602) unnamed protein product [Homo sapiens]
          Length = 389

 Score =  119 bits (300), Expect = 7e-27
 Identities = 30/131 (22%), Positives = 67/131 (50%), Gaps = 15/131 (11%)

Query: 1   MKKIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKW-DINKGQEVPLFMERGIQQ-SD 58
           ++K+FI+Y+ D     +V+K    L     F+ + D + D  +G ++  +MER ++  + 
Sbjct: 224 LRKVFITYSMDTA--MEVVKFVNFLL-VNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTV 280

Query: 59  FVLIICSERYK---------VNADKRRGGSGYEARLMSDEVLRNEDKD-RFIPIILNEKD 108
            +++  S +YK         ++ D+    + Y  R+M  E ++    + RFIP++     
Sbjct: 281 MIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAK 340

Query: 109 KKNIPNFLKSK 119
           K+++P +L++ 
Sbjct: 341 KEHVPTWLQNT 351



>gi|21464280|gb|AAM51943.1|   (AY121616) GH03720p [Drosophila melanogaster]
          Length = 732

 Score =  119 bits (300), Expect = 7e-27
 Identities = 27/125 (21%), Positives = 48/125 (37%), Gaps = 13/125 (10%)

Query: 5   FISYAWDEIEDEKVIKLAEMLED-YKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLII 63
           FISY+  +    +   L   LE   ++F++   + D   G  +P  + R +  S   +I+
Sbjct: 497 FISYSHKDQSFIE-DYLVPQLEHGPQKFQLCVHERDWLVGGHIPENIMRSVADSRRTIIV 555

Query: 64  CSERYKVNADKRRGGSGYEARLMSDEVLR--NEDKDRFIPIIL-NEKDKKNIPNFLKSKL 120
            S+ +          S +             NE + R I II  +  D + +   LK+ L
Sbjct: 556 LSQNF--------IKSEWARLEFRAAHRSALNEGRSRIIVIIYSDIGDVEKLDEELKAYL 607

Query: 121 WTELY 125
               Y
Sbjct: 608 KMNTY 612



>gi|21294921|gb|EAA07066.1|   (AAAB01008848) agCP7198 [Anopheles gambiae str. PEST]
          Length = 945

 Score =  119 bits (298), Expect = 1e-26
 Identities = 27/124 (21%), Positives = 52/124 (41%), Gaps = 11/124 (8%)

Query: 5   FISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLIIC 64
           FISY+  + E      L ++  +   F++ +   D   G+ +   + + +++S   +II 
Sbjct: 755 FISYSHKDEEFVTKELLPKLESEELNFKICWHVRDFMPGEMIANEITKAVEESRRTIIIL 814

Query: 65  SERYKVNADKRRGGSGYEARLMSDEVLRNEDK--DRFIPIIL-NEKDKKNIPNFLKSKLW 121
           S  Y          S +     S   L++     +R IPII  +  D + +   L++ L 
Sbjct: 815 SLNY--------LESVWGQIEFSTAYLQSLADKCNRVIPIIYQDIGDIEQLDPQLQAYLK 866

Query: 122 TELY 125
           T  Y
Sbjct: 867 TNTY 870



>gi|21292807|gb|EAA04952.1|   (AAAB01008811) agCP4196 [Anopheles gambiae str. PEST]
          Length = 1007

 Score =  118 bits (297), Expect = 1e-26
 Identities = 27/124 (21%), Positives = 51/124 (40%), Gaps = 11/124 (8%)

Query: 5   FISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLIIC 64
           FISY+  + E      L  +  +   F++ +   D   G+ +   + + ++ S   +II 
Sbjct: 852 FISYSHKDEEFVTDQMLPRLESEELNFKICWHVRDFMPGEMIASQITKAVEDSRRTIIIL 911

Query: 65  SERYKVNADKRRGGSGYEARLMSDEVLRN--EDKDRFIPIIL-NEKDKKNIPNFLKSKLW 121
           S  Y          S +     S   L++  + ++R IPII  +  D   +   L++ L 
Sbjct: 912 SHNY--------LESVWGQMEFSTAYLQSLEDKRNRVIPIIYQDIGDIDQLDPELQAYLK 963

Query: 122 TELY 125
           T  Y
Sbjct: 964 TNTY 967



>gi|17229067|ref|NP_485615.1|   (NC_003272) unknown protein [Nostoc sp. PCC 7120]
 gi|17135395|dbj|BAB77941.1|   (AP003586) ORF_ID:alr1575~unknown protein [Nostoc sp. PCC 7120]
          Length = 1047

 Score =  117 bits (295), Expect = 3e-26
 Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 14/141 (9%)

Query: 1   MKKIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFV 60
           M ++F+SY+ +E       K+A++L     F V  +K DI  G +    + RGI+++D V
Sbjct: 235 MTQVFLSYSENERLFM--EKIAKILMRES-FTVWTNKTDIQSGADFTESINRGIEEADNV 291

Query: 61  LIICSERYKVNADKRRGGSGYEARLMSDEVLRNEDKDRFIPIILNEKDKKNIPNFLKSKL 120
           +++ S             S Y    +S        K R IP+++   D + IP  L    
Sbjct: 292 VLLLST--------ASLQSEYCQMELSYAFSL---KKRIIPLLIEPVDIEQIPVELSILQ 340

Query: 121 WTELYHDEQSMEYNNQLDDLL 141
           + +    E+  + +   D L+
Sbjct: 341 FIDFTDQEEQGKESADTDRLI 361




 Score = 38.9 bits (90), Expect = 0.016
 Identities = 27/140 (19%), Positives = 47/140 (33%), Gaps = 19/140 (13%)

Query: 4   IFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLII 63
           +FISY+  + +     KL + L+  +     FD+  I  G      + RGI+ ++  L I
Sbjct: 440 VFISYSRADSDFA--RKLNDTLQ-IQNKTTWFDQESIASGTNFEQEIYRGIESANNFLFI 496

Query: 64  CSERYKVNADKRRGGSGYEARLMSDEVLRNEDKDRFIPIILNEKDKKNIPNFLKSKLW-- 121
            S +           S Y    +   +  N    R + ++  E     +   L    W  
Sbjct: 497 ISPK--------SLSSPYCTTEVEYAMNLN---KRIVTVLYREIKGATLHPGLAKVQWID 545

Query: 122 ---TELYHDEQSMEYNNQLD 138
                     +  E    LD
Sbjct: 546 FSQHNTDFLTKFGELTRTLD 565




 Score = 35.1 bits (80), Expect = 0.27
 Identities = 24/99 (24%), Positives = 42/99 (42%), Gaps = 13/99 (13%)

Query: 5   FISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLIIC 64
           FISY   + +     KL +   +    ++ FD+ DI  G +    ++ GI++SD  L I 
Sbjct: 8   FISYGRADSK-AFATKLHQRFVEA-GLDIWFDQNDIPLGVDFQNQIDDGIEKSDNFLFII 65

Query: 65  SERYKVNADKRRGGSGYEARLMSDEVLRNEDKDRFIPII 103
           +             S Y  + +   + RN    R IP++
Sbjct: 66  AP--------HSVNSPYCGKEIDLALRRN---KRIIPLL 93



>gi|21292746|gb|EAA04891.1|   (AAAB01008811) agCP4197 [Anopheles gambiae str. PEST]
          Length = 964

 Score =  117 bits (294), Expect = 3e-26
 Identities = 26/124 (20%), Positives = 51/124 (40%), Gaps = 11/124 (8%)

Query: 5   FISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLIIC 64
           FISY+  + E      L  +  +   F++ +   D   G+ +   + + ++ S   +II 
Sbjct: 800 FISYSHKDEEFVTGQMLPRLESEELNFKICWHVRDFMPGEMIASQITKAVEDSRRTIIIL 859

Query: 65  SERYKVNADKRRGGSGYEARLMSDEVLRN--EDKDRFIPIIL-NEKDKKNIPNFLKSKLW 121
           S  Y          S +     +   L++  + ++R IPII  +  D   +   L++ L 
Sbjct: 860 SHNY--------LESVWGQMEFNTAYLQSLEDKRNRVIPIIYQDIGDIDQLDPELQAYLK 911

Query: 122 TELY 125
           T  Y
Sbjct: 912 TNTY 915



>gi|21674286|ref|NP_662351.1|   (NC_002932) TIR domain protein [Chlorobium tepidum TLS]
 gi|21647457|gb|AAM72693.1|   (AE012903) TIR domain protein [Chlorobium tepidum TLS]
          Length = 315

 Score =  117 bits (293), Expect = 4e-26
 Identities = 34/146 (23%), Positives = 68/146 (46%), Gaps = 18/146 (12%)

Query: 3   KIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFM-ERGIQQSDFVL 61
           K+F+S+A ++ +   V++ AE L   K  +   DKW++  G  +   + E GI+++  V+
Sbjct: 4   KVFVSHASEDKD-RFVLQFAERLRQ-KGIDAWLDKWEMLPGDSLVDKIFEEGIKEAKAVI 61

Query: 62  IICSE-RYKVNADKRRGGSGYEARLMSDEVLRNEDKDRFIPIILNEKDKKNIPNFLKSKL 120
           ++ S+   +    +    + +  R+ +          + IPI+    D   +P  LKS L
Sbjct: 62  VVLSKFSVEKPWVREELNAAFVKRINNG--------SKLIPIV---IDDCEVPEALKSTL 110

Query: 121 WTELYHDEQSMEYNNQLDDLLATIIG 146
           W  +        Y+   D ++A+I G
Sbjct: 111 WEPI---ADLSAYDKSFDRIVASIYG 133



>gi|6537248|gb|AAF15574.1|   (AF185639) Toll-related protein [Aedes aegypti]
          Length = 118

 Score =  116 bits (291), Expect = 7e-26
 Identities = 22/124 (17%), Positives = 48/124 (37%), Gaps = 11/124 (8%)

Query: 5   FISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLIIC 64
           FISY+  + E      +  + ++   F+  +   D   G+ +P  + + ++ S   +++ 
Sbjct: 1   FISYSHKDEEFITEHLVPTLEKEPMNFKTCWHVRDWMPGELIPTQIAKSVEDSRRTIVVL 60

Query: 65  SERYKVNADKRRGGSGYEARLMSDEVLRN--EDKDRFIPIIL-NEKDKKNIPNFLKSKLW 121
           S  +          S +         L +  E + R I II  +    +++   LK+ L 
Sbjct: 61  STNF--------LESVWGRMEFRTAHLTSMEEKRARVIVIIYGDIGSIEDLDPELKAYLK 112

Query: 122 TELY 125
              Y
Sbjct: 113 MNTY 116



>gi|21361425|ref|NP_055154.2|   (NM_014339) interleukin 17 receptor [Homo sapiens]
 gi|20454982|sp|Q96F46|I17R_HUMAN   Interleukin-17 receptor precursor (IL-17 receptor)
 gi|15079611|gb|AAH11624.1|AAH11624   (BC011624) Similar to interleukin 17 receptor [Homo sapiens]
          Length = 866

 Score =  114 bits (287), Expect = 2e-25
 Identities = 22/154 (14%), Positives = 51/154 (32%), Gaps = 26/154 (16%)

Query: 2   KKIFISYAWDEIEDEKVI-KLAEMLEDYKEFEVSFDKWDI--NKGQEVPLFMERGIQQSD 58
           +K++I Y+ D      V+ K A+ L      EV+ D  +        V  ++ R  Q+  
Sbjct: 378 RKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWVGRQKQEMV 437

Query: 59  ----FVLIICSERYKVNADK----------RRGGSG-----YEARLMSD--EVLRNEDKD 97
                ++++CS   +               R          + A +     +  R     
Sbjct: 438 ESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFTAAMNMILPDFKRPACFG 497

Query: 98  RFIPIILNE-KDKKNIPNFL-KSKLWTELYHDEQ 129
            ++    +E     ++P+    +  +  +   E+
Sbjct: 498 TYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEE 531



>gi|2826476|gb|AAB99730.1|   (U58917) IL-17 receptor [Homo sapiens]
          Length = 866

 Score =  114 bits (287), Expect = 2e-25
 Identities = 22/154 (14%), Positives = 51/154 (32%), Gaps = 26/154 (16%)

Query: 2   KKIFISYAWDEIEDEKVI-KLAEMLEDYKEFEVSFDKWDI--NKGQEVPLFMERGIQQSD 58
           +K++I Y+ D      V+ K A+ L      EV+ D  +        V  ++ R  Q+  
Sbjct: 378 RKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWVGRQKQEMV 437

Query: 59  ----FVLIICSERYKVNADK----------RRGGSG-----YEARLMSD--EVLRNEDKD 97
                ++++CS   +               R          + A +     +  R     
Sbjct: 438 ESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFTAAMNMILPDFKRPACFG 497

Query: 98  RFIPIILNE-KDKKNIPNFL-KSKLWTELYHDEQ 129
            ++    +E     ++P+    +  +  +   E+
Sbjct: 498 TYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEE 531



>gi|6981721|gb|AAF15575.2|AF185640_1   (AF185640) toll-related protein [Aedes aegypti]
          Length = 119

 Score =  113 bits (283), Expect = 6e-25
 Identities = 20/125 (16%), Positives = 43/125 (34%), Gaps = 16/125 (12%)

Query: 9   AWDEIEDEKVIKLAEMLED-----YKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLII 63
             D    +    + E L          F+  +   D   G+ +P+ + + ++ S   +++
Sbjct: 1   TSDSYSHKDEEFITEHLVPTLEKEPMNFKTCWHVRDWMPGELIPMQIAKSVEDSRRTIVV 60

Query: 64  CSERYKVNADKRRGGSGYEARLMSDEVLRN--EDKDRFIPIIL-NEKDKKNIPNFLKSKL 120
            S  +          S +         L +  E + R I II  +    +++   LK+ L
Sbjct: 61  LSTNF--------LESVWGRMEFRTAHLTSMEEKRARVIVIIYGDIGSIEDLDPELKAYL 112

Query: 121 WTELY 125
               Y
Sbjct: 113 KMNTY 117



>gi|6537252|gb|AAF15576.1|AF185641_1   (AF185641) Toll [Anopheles gambiae]
          Length = 116

 Score =  112 bits (280), Expect = 2e-24
 Identities = 23/124 (18%), Positives = 47/124 (37%), Gaps = 11/124 (8%)

Query: 5   FISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLIIC 64
           F+SY+  +        +  +  D   F++ +   D   G+ +   +   ++QS   +I+ 
Sbjct: 1   FVSYSHKDEAFITEHLVPTLERDPMNFKLCWHVRDWTPGEMISSQISSSVEQSRRTIIVL 60

Query: 65  SERYKVNADKRRGGSGYEARLMSDEVLRNEDKDRFIPIILNEKDKKNIPN---FLKSKLW 121
           S  +          S +         L++  + R   II+   D  NI +    L++ L 
Sbjct: 61  SSSF--------LESLWGQLEFRTAHLQSMAERRNRLIIIIYGDIGNIYDLEPELRAYLH 112

Query: 122 TELY 125
           T  Y
Sbjct: 113 TNTY 116



>gi|6680411|ref|NP_032385.1|   (NM_008359) interleukin 17 receptor [Mus musculus]
 gi|20454961|sp|Q60943|I17R_MOUSE   Interleukin-17 receptor precursor (IL-17 receptor)
 gi|1161343|gb|AAC52357.1|   (U31993) interleukin 17 receptor [Mus musculus]
          Length = 864

 Score =  111 bits (279), Expect = 2e-24
 Identities = 22/155 (14%), Positives = 52/155 (33%), Gaps = 27/155 (17%)

Query: 2   KKIFISYAWDEIEDEKVI-KLAEMLEDYKEFEVSFDKWDI--NKGQEVPLFMERGIQQSD 58
           +K++I Y+ D     +V+ K A+ L      EV+ D  +        V  ++ R  Q+  
Sbjct: 380 RKVWIVYSADHPLYVEVVLKFAQFLITACGTEVALDLLEEQVISEVGVMTWVSRQKQEMV 439

Query: 59  ----FVLIICSERYKVNAD--------------KRRGGSG--YEARLMSD--EVLRNEDK 96
                ++I+CS   +                       +G  + A +     +  R    
Sbjct: 440 ESNSKIIILCSRGTQAKWKAILGWAEPAVQLRCDHWKPAGDLFTAAMNMILPDFKRPACF 499

Query: 97  DRFIPIILNEKDKK-NIPNFLKSK-LWTELYHDEQ 129
             ++    +    + ++P+       +  +   E+
Sbjct: 500 GTYVVCYFSGICSERDVPDLFNITSRYPLMDRFEE 534



>gi|466395|gb|AAA28943.1|   (L25391) Toll protein [Drosophila virilis]
          Length = 123

 Score =  110 bits (275), Expect = 6e-24
 Identities = 26/125 (20%), Positives = 46/125 (36%), Gaps = 13/125 (10%)

Query: 5   FISYAWDEIEDEKVIKLAEMLED-YKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLII 63
           FISY+  +    +   L   LE   ++F +     D   G  +P  + R +  S   +I+
Sbjct: 2   FISYSHKDQSFVE-QHLVPQLEHGPQKFTLCVHVRDWLVGGFIPENIVRSVADSRRTIIV 60

Query: 64  CSERYKVNADKRRGGSGYEARLMSDEV--LRNEDKDRFIPIIL-NEKDKKNIPNFLKSKL 120
            S  +          S +             NE + R I II  +  D + + + +K+ L
Sbjct: 61  LSPNF--------IKSDWARMEFRAAHRAALNEGRSRVIVIIYSDIGDIEQLDDEMKAYL 112

Query: 121 WTELY 125
               Y
Sbjct: 113 RMNTY 117



>gi|21294894|gb|EAA07039.1|   (AAAB01008848) agCP7266 [Anopheles gambiae str. PEST]
          Length = 998

 Score =  108 bits (271), Expect = 2e-23
 Identities = 26/131 (19%), Positives = 51/131 (38%), Gaps = 18/131 (13%)

Query: 5   FISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPL-------FMERGIQQS 57
           FISY+  + +      L  +  +   F++ +   D   G+ +          + + +++S
Sbjct: 826 FISYSHKDEDFVTKELLPRLESEELNFKICWHVRDFVPGEMIANELLYYSFQIAKAVEES 885

Query: 58  DFVLIICSERYKVNADKRRGGSGYEARLMSDEVLRN--EDKDRFIPIIL-NEKDKKNIPN 114
              +II S  Y          S +     S   L++  +  +R IPII  +  D   +  
Sbjct: 886 RRTIIILSLNYF--------ESMWGQMEFSAAYLQSLVDKHNRVIPIIYQDIGDIDQLDP 937

Query: 115 FLKSKLWTELY 125
            L++ L T  Y
Sbjct: 938 QLRAYLKTNTY 948



>gi|21291458|gb|EAA03603.1|   (AAAB01008796) agCP1910 [Anopheles gambiae str. PEST]
          Length = 155

 Score =  107 bits (268), Expect = 4e-23
 Identities = 28/124 (22%), Positives = 49/124 (38%), Gaps = 11/124 (8%)

Query: 5   FISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLIIC 64
           FISYA  + E      L     +   F++ +   D   G+ +     + +++S   +II 
Sbjct: 32  FISYAHKDEEFVTKELLPRFESEELNFKICWHVRDFMPGEMIANETTKAVEESRRTIIIL 91

Query: 65  SERYKVNADKRRGGSGYEARLMSDEVLRNEDK--DRFIPIIL-NEKDKKNIPNFLKSKLW 121
           S  Y          S +     S   L++     +R IPII  +  D + +   L++ L 
Sbjct: 92  SLNY--------LESVWGQIEFSTAYLQSLADKCNRVIPIIYQDIGDIEQLDPQLQAYLK 143

Query: 122 TELY 125
           T  Y
Sbjct: 144 TNTY 147



>gi|6425008|gb|AAF08257.1|   (AF185646) Toll protein [Drosophila simulans]
          Length = 118

 Score =  107 bits (268), Expect = 4e-23
 Identities = 27/125 (21%), Positives = 48/125 (37%), Gaps = 13/125 (10%)

Query: 5   FISYAWDEIEDEKVIKLAEMLED-YKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLII 63
           FISY+  +    +   L   LE   ++F++   + D   G  +P  + R +  S   +I+
Sbjct: 1   FISYSHKDQSFIE-DYLVPQLEHGPQKFQLCVHERDWLVGGHIPENIMRSVADSRRTIIV 59

Query: 64  CSERYKVNADKRRGGSGYEARLMSDEVLR--NEDKDRFIPIIL-NEKDKKNIPNFLKSKL 120
            S+ +          S +             NE + R I II  +  D + +   LK+ L
Sbjct: 60  LSQNF--------IKSEWARLEFRAAHRSALNEGRSRIIVIIYSDIGDVEKLDEELKAYL 111

Query: 121 WTELY 125
               Y
Sbjct: 112 KMNTY 116



>gi|6537258|gb|AAF15579.1|AF185644_1   (AF185644) Toll-related protein [Glossina palpalis palpalis]
          Length = 118

 Score =  107 bits (267), Expect = 5e-23
 Identities = 27/125 (21%), Positives = 49/125 (38%), Gaps = 13/125 (10%)

Query: 5   FISYAWDEIEDEKVIKLAEMLED-YKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLII 63
           FISY+  + +      L   LE+    F++     D   G  +P  + R I +S   +++
Sbjct: 1   FISYSHKDQQFI-ADYLVPQLENGPIPFKLCVHVRDFIVGDFIPDQIIRSIDESRRTIVV 59

Query: 64  CSERYKVNADKRRGGSGYEARLMSDEVL--RNEDKDRFIPIIL-NEKDKKNIPNFLKSKL 120
            S+ +          S +             NE + R I II  +  D + + + L++ L
Sbjct: 60  LSQNF--------IESIWARLEFKIAHKAALNEGRARVIVIIYGDIGDIEKLESDLQAYL 111

Query: 121 WTELY 125
            T  Y
Sbjct: 112 KTNTY 116



>gi|8923817|ref|NP_061195.1|   (NM_018725) IL-17B receptor [Homo sapiens]
 gi|8705222|gb|AAF78776.1|AF212365_1   (AF212365) IL-17B receptor [Homo sapiens]
          Length = 426

 Score =  105 bits (263), Expect = 2e-22
 Identities = 15/89 (16%), Positives = 30/89 (32%), Gaps = 2/89 (2%)

Query: 3   KIFISYAWDEIEDEKVIKLAEMLEDYKEFEVSFDKWD--INKGQEVPLFMERGIQQSDFV 60
           K+ + Y  +      +    E L+++   EV  +KW            ++    + +D V
Sbjct: 333 KVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQKKAADKV 392

Query: 61  LIICSERYKVNADKRRGGSGYEARLMSDE 89
           + + S       D   G S       S +
Sbjct: 393 VFLLSNDVNSVCDGTCGKSEGSPSENSQD 421



>gi|17137686|ref|NP_477438.1|   (NM_058090) Tehao-P1; tehao [Drosophila melanogaster]
 gi|7298066|gb|AAF53306.1|   (AE003640) Tehao gene product [Drosophila melanogaster]
          Length = 795

 Score =  103 bits (258), Expect = 5e-22
 Identities = 27/125 (21%), Positives = 45/125 (35%), Gaps = 14/125 (11%)

Query: 5   FISYAWDEIEDEKVIKLAEMLED-YKEFEVSFDKWDINKGQEVPLFMERGIQQSDFVLII 63
           FISY+    ++E + KL   LE     F +     D   G  +P  + R +  S  V+I+
Sbjct: 647 FISYSHK--DEELISKLLPKLESGPHPFRLCLHDRDWLVGDCIPEQIVRTVDDSKRVIIV 704

Query: 64  CSERYKVNADKRRGGSGYEARLMSDEVL--RNEDKDRFIPIILNEK-DKKNIPNFLKSKL 120
            S+            S +              + + R I I+  E      I + L++ L
Sbjct: 705 LSQ--------HFIDSVWARMEFRIAYQATLQDKRKRIIIILYRELEHMNGIDSELRAYL 756

Query: 121 WTELY 125
               Y
Sbjct: 757 KLNTY 761






  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF
    Posted date:  Sep 4, 2002 12:20 AM
  Number of letters in database: 330,426,180
  Number of sequences in database:  1,044,513
  
Lambda     K      H
   0.317    0.167    0.435 

Gapped
Lambda     K      H
   0.267   0.0512    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 111,468,973
Number of Sequences: 1044513
Number of extensions: 5019473
Number of successful extensions: 13212
Number of sequences better than 10.0: 321
Number of HSP's better than 10.0 without gapping: 210
Number of HSP's successfully gapped in prelim test: 111
Number of HSP's that attempted gapping in prelim test: 12728
Number of HSP's gapped (non-prelim): 333
length of query: 150
length of database: 330,426,180
effective HSP length: 110
effective length of query: 40
effective length of database: 215,529,750
effective search space: 8621190000
effective search space used: 8621190000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.3 bits)
S2: 66 (29.7 bits)