cellular organisms . Bacteria [eubacteria] . . Staphylococcus hominis ------------------------------ 182 1 hit [Gram+ bacteria] (AB063171) ORF22 [Staphylococcus hominis] . . Streptomyces coelicolor A3(2) ....................... 135 2 hits [high GC Gram+] (NC_003888) putative ATP /GTP-binding protein [Streptomyces . . Chlorobium tepidum TLS .............................. 129 1 hit [green sulfur bacteria] (NC_002932) TIR domain protein [Chlorobium tepidum TLS] >gi . . Nostoc sp. PCC 7120 ................................. 125 2 hits [cyanobacteria] (NC_003272) unknown protein [Nostoc sp. PCC 7120] >gi|17135 . . Agrobacterium tumefaciens ........................... 104 1 hit [a-proteobacteria] (NC_002377) ymc [Agrobacterium tumefaciens] >gi|5738269|gb| . . Fusobacterium nucleatum subsp. nucleatum ATCC 25586 . 37 1 hit [fusobacteria] (NC_003454) WD-repeat family protein [Fusobacterium nucleat . . Thermosynechococcus elongatus BP-1 .................. 36 1 hit [cyanobacteria] (NC_004113) serine/threonine protein kinase [Thermosynechoc . Homo sapiens (man) ------------------------------------ 167 30 hits [mammals] (AF458067) IL-17RD [Homo sapiens] . Mus musculus (mouse) .................................. 166 18 hits [mammals] (AF459444) transmembrane protein [Mus musculus] >gi|2166750 . Danio rerio (zebra danio) ............................. 144 2 hits [bony fishes] (AF364103) Sef [Danio rerio] . Methanosarcina mazei Goe1 ............................. 107 1 hit [euryarchaeotes] (NC_003901) hypothetical protein [Methanosarcina mazei Goe1 . Aedes aegypti ......................................... 102 5 hits [flies] (AY124197) Toll-related protein; AeToll1B [Aedes aegypti] . Anopheles gambiae ..................................... 61 6 hits [flies] (AF444780) Toll [Anopheles gambiae] . Anopheles gambiae str. PEST ........................... 57 6 hits [flies] (AAAB01008811) agCP4196 [Anopheles gambiae str. PEST] . Drosophila pseudoobscura .............................. 52 1 hit [flies] (L25390) Toll protein [Drosophila pseudoobscura] . Drosophila melanogaster ............................... 52 9 hits [flies] (AY121616) GH03720p [Drosophila melanogaster] . Drosophila virilis .................................... 52 1 hit [flies] (L25391) Toll protein [Drosophila virilis] . Glossina palpalis palpalis ............................ 48 1 hit [flies] (AF185644) Toll-related protein [Glossina palpalis palpalis] . Drosophila simulans ................................... 46 2 hits [flies] (AF185646) Toll protein [Drosophila simulans] . Bos taurus (bovine) ................................... 43 2 hits [mammals] Toll-like receptor 2 precursor >gi|16266041|gb|AAL16722.1|A . Gallus gallus (chickens) .............................. 43 2 hits [birds] Toll-like receptor 2 type 2 precursor >gi|10863071|dbj|BAB1 . Macaca fascicularis (crab eating macaque) ............. 42 1 hit [mammals] Toll-like receptor 2 precursor >gi|15281146|gb|AAK91868.1| . Caenorhabditis elegans ................................ 40 1 hit [nematodes] (NM_070335) Y64G10A.6.p [Caenorhabditis elegans] >gi|751035 . Arabidopsis thaliana (mouse-ear cress) ................ 40 1 hit [eudicots] (NM_123859) disease resistance protein (TIR class), putativ . Oryctolagus cuniculus (domestic rabbit) ............... 38 1 hit [mammals] (AY101393) toll-like receptor 2 [Oryctolagus cuniculus] . Cricetulus griseus (Chinese hamsters) ................. 38 1 hit [mammals] Toll-like receptor 2 precursor . Rattus norvegicus (brown rat) ......................... 36 1 hit [mammals] Toll-like receptor 4 precursor (Toll4) >gi|3044208|gb|AAC13
Staphylococcus hominis [Gram+ bacteria] taxid 1290 gi|18148891|dbj|BAB83481.1| (AB063171) ORF22 [Staphylococc... 182 7e-46 Homo sapiens (man) [mammals] taxid 9606 gi|21779863|gb|AAM77571.1|AF458067_1 (AF458067) IL-17RD [H... 167 3e-41 gi|21667504|gb|AAM74077.1|AF494208_1 (AF494208) interleuki... 167 3e-41 gi|11360138|pir||T42695 hypothetical protein DKFZp434N1928... 166 9e-41 gi|21667510|gb|AAM74080.1|AF494211_1 (AF494211) interleuki... 165 1e-40 gi|14726669|ref|XP_045300.1| (XM_045300) similar to peptid... 165 1e-40 gi|21263748|sp|Q9NRM6|I17S_HUMAN Interleukin-17B receptor ... 162 9e-40 gi|9246433|gb|AAF86051.1|AF208110_1 (AF208110) IL-17 recep... 160 4e-39 gi|10437850|dbj|BAB15117.1| (AK025351) unnamed protein pro... 134 2e-31 gi|21361425|ref|NP_055154.2| (NM_014339) interleukin 17 re... 134 2e-31 gi|2826476|gb|AAB99730.1| (U58917) IL-17 receptor [Homo sa... 134 2e-31 gi|21758050|dbj|BAC05236.1| (AK098107) unnamed protein pro... 130 4e-30 gi|19923427|ref|NP_056339.2| (NM_015524) chromosome 6 open... 130 5e-30 gi|10257415|gb|AAG15407.1|AF272151_1 (AF272151) adaptor pr... 130 5e-30 gi|22538428|ref|NP_679211.1| (NM_147686) chromosome 6 open... 130 5e-30 gi|22538426|ref|NP_671733.1| (NM_147200) chromosome 6 open... 130 5e-30 gi|2842416|emb|CAA15506.1| (AL008730) dJ487J7.1.1 (putativ... 130 5e-30 gi|10439491|dbj|BAB15507.1| (AK026602) unnamed protein pro... 130 5e-30 gi|8923817|ref|NP_061195.1| (NM_018725) IL-17B receptor [H... 121 2e-27 gi|2842417|emb|CAA15507.1| (AL008730) dJ487J7.1.2 (putativ... 70 4e-12 gi|2459624|gb|AAC34133.1| (U88878) Toll-like receptor 2 [H... 42 0.001 gi|19718734|ref|NP_003255.2| (NM_003264) toll-like recepto... 42 0.002 gi|1588367|prf||2208371A interleukin 1 receptor-like prote... 39 0.009 gi|4504655|ref|NP_003846.1| (NM_003855) interleukin 18 rec... 38 0.023 gi|286015|dbj|BAA02801.1| (D13637) KIAA0012 [Homo sapiens] 37 0.040 gi|7513378|pir||T08664 Toll protein-like receptor DKFZp547... 37 0.041 gi|4507527|ref|NP_003254.1| (NM_003263) toll-like receptor... 37 0.043 gi|11513559|pdb|1FYV|A Chain A, Crystal Structure Of The T... 37 0.052 gi|20140925|sp|Q9Y2C9|TLR6_HUMAN Toll-like receptor 6 prec... 36 0.070 gi|20143971|ref|NP_006059.2| (NM_006068) toll-like recepto... 36 0.074 gi|11513561|pdb|1FYW|A Chain A, Crystal Structure Of The T... 35 0.18 Mus musculus (mouse) [mammals] taxid 10090 gi|20799328|gb|AAM28441.1|AF459444_1 (AF459444) transmembr... 166 7e-41 gi|20872095|ref|XP_127630.1| (XM_127630) similar expressio... 165 1e-40 gi|18845019|gb|AAL79530.1|AF424804_1 (AF424804) similar ex... 164 3e-40 gi|21667506|gb|AAM74078.1|AF494209_1 (AF494209) interleuki... 164 3e-40 gi|20872223|ref|XP_127670.1| (XM_127670) similar to IL-17 ... 146 8e-35 gi|6680411|ref|NP_032385.1| (NM_008359) interleukin 17 rec... 130 6e-30 gi|19527222|ref|NP_598761.1| (NM_134000) expressed sequenc... 71 2e-12 gi|12836693|dbj|BAB23770.1| (AK005043) data source:MGD, so... 40 0.006 gi|20872493|ref|XP_124093.1| (XM_124093) toll-like recepto... 40 0.006 gi|6755813|ref|NP_036035.1| (NM_011905) toll-like receptor... 40 0.006 gi|21955346|gb|AAH14693.1| (BC014693) Unknown (protein for... 40 0.006 gi|20140792|sp|Q9EPW9|TLR6_MOUSE Toll-like receptor 6 prec... 36 0.073 gi|11596326|gb|AAG38563.1|AF314636_1 (AF314636) toll-like ... 36 0.074 gi|6755815|ref|NP_035734.1| (NM_011604) toll-like receptor... 36 0.074 gi|20985053|ref|XP_142018.1| (XM_142018) similar to Toll-l... 36 0.098 gi|13507603|ref|NP_109607.1| (NM_030682) toll-like recepto... 35 0.15 gi|11385997|gb|AAG35062.1|AF316985_1 (AF316985) toll-like ... 35 0.15 gi|18875360|ref|NP_573474.1| (NM_133211) toll-like recepto... 35 0.21 Danio rerio (zebra danio, ...) [bony fishes] taxid 7955 gi|18623501|gb|AAL76112.1|AF364103_1 (AF364103) Sef [Danio... 144 3e-34 gi|18765887|gb|AAL78817.1|AF401232_1 (AF401232) FGF signal... 144 3e-34 Streptomyces coelicolor A3(2) [high GC Gram+] taxid 100226 gi|21223984|ref|NP_629763.1| (NC_003888) putative ATP /GTP... 135 1e-31 gi|21223014|ref|NP_628793.1| (NC_003888) putative ATP/GTP ... 135 1e-31 Chlorobium tepidum TLS [green sulfur bacteria] taxid 194439 gi|21674286|ref|NP_662351.1| (NC_002932) TIR domain protei... 129 9e-30 Nostoc sp. PCC 7120 [cyanobacteria] taxid 103690 gi|17229067|ref|NP_485615.1| (NC_003272) unknown protein [... 125 2e-28 Methanosarcina mazei Goe1 [euryarchaeotes] taxid 192952 gi|21228803|ref|NP_634725.1| (NC_003901) hypothetical prot... 107 3e-23 Agrobacterium tumefaciens [a-proteobacteria] taxid 358 gi|10955119|ref|NP_059775.1| (NC_002377) ymc [Agrobacteriu... 104 2e-22 Aedes aegypti [flies] taxid 7159 gi|22651846|gb|AAM97776.1| (AY124197) Toll-related protein... 102 1e-21 gi|22651844|gb|AAM97775.1| (AY124196) Toll-related protein... 68 2e-11 gi|22651842|gb|AAM97774.1| (AY124195) Toll-related protein... 65 2e-10 gi|6537248|gb|AAF15574.1| (AF185639) Toll-related protein ... 62 9e-10 gi|6981721|gb|AAF15575.2|AF185640_1 (AF185640) toll-relate... 58 1e-08 Anopheles gambiae [flies] taxid 7165 gi|17226676|gb|AAL37901.1|AF444780_1 (AF444780) Toll [Anop... 61 4e-09 gi|6537252|gb|AAF15576.1|AF185641_1 (AF185641) Toll [Anoph... 56 1e-07 gi|6537254|gb|AAF15577.1|AF185642_1 (AF185642) Toll-relate... 44 3e-04 gi|17226678|gb|AAL37902.1| (AF444781) Toll6 [Anopheles gam... 39 0.009 gi|17226682|gb|AAL37904.1|AF444783_1 (AF444783) Trex [Anop... 39 0.011 gi|6537256|gb|AAF15578.1|AF185643_1 (AF185643) Toll-relate... 35 0.21 Anopheles gambiae str. PEST [flies] taxid 180454 gi|21292807|gb|EAA04952.1| (AAAB01008811) agCP4196 [Anophe... 57 4e-08 gi|21292746|gb|EAA04891.1| (AAAB01008811) agCP4197 [Anophe... 54 3e-07 gi|21294921|gb|EAA07066.1| (AAAB01008848) agCP7198 [Anophe... 54 4e-07 gi|21291458|gb|EAA03603.1| (AAAB01008796) agCP1910 [Anophe... 47 6e-05 gi|21288059|gb|EAA00380.1| (AAAB01008986) agCP9368 [Anophe... 39 0.014 gi|21288058|gb|EAA00379.1| (AAAB01008986) ebiP8963 [Anophe... 38 0.021 Drosophila pseudoobscura [flies] taxid 7237 gi|466393|gb|AAA28942.1| (L25390) Toll protein [Drosophila... 52 1e-06 Drosophila melanogaster [flies] taxid 7227 gi|21464280|gb|AAM51943.1| (AY121616) GH03720p [Drosophila... 52 1e-06 gi|17738225|ref|NP_524518.1| (NM_079794) Toll [Drosophila ... 52 1e-06 gi|9246967|gb|AAF86227.1|AF247767_1 (AF247767) Toll-5 [Dro... 50 8e-06 gi|17137686|ref|NP_477438.1| (NM_058090) Tehao-P1; tehao [... 50 8e-06 gi|4809185|gb|AAD30131.1|AF140019_1 (AF140019) Toll like p... 49 1e-05 gi|1223896|gb|AAC46999.1| (U42425) DmMstProx [Drosophila m... 41 0.004 gi|9246971|gb|AAF86229.1|AF247769_1 (AF247769) Toll-3 [Dro... 41 0.004 gi|7297490|gb|AAF52747.1| (AE003623) Toll-4 gene product [... 39 0.011 gi|9246969|gb|AAF86228.1|AF247768_1 (AF247768) Toll-4 [Dro... 38 0.017 Drosophila virilis [flies] taxid 7244 gi|466395|gb|AAA28943.1| (L25391) Toll protein [Drosophila... 52 2e-06 Glossina palpalis palpalis [flies] taxid 66268 gi|6537258|gb|AAF15579.1|AF185644_1 (AF185644) Toll-relate... 48 2e-05 Drosophila simulans [flies] taxid 7240 gi|6425008|gb|AAF08257.1| (AF185646) Toll protein [Drosoph... 46 8e-05 gi|6425006|gb|AAF08256.1| (AF185645) Tehao protein [Drosop... 40 0.004 Bos taurus (bovine, ...) [mammals] taxid 9913 gi|20140688|sp|Q95LA9|TLR2_BOVIN Toll-like receptor 2 prec... 43 6e-04 gi|11141768|gb|AAG32060.1|AF310951_1 (AF310951) Toll-like ... 40 0.008 Gallus gallus (chickens) [birds] taxid 9031 gi|20140787|sp|Q9DGB6|TL22_CHICK Toll-like receptor 2 type... 43 8e-04 gi|20140785|sp|Q9DD78|TL21_CHICK Toll-like receptor 2 type... 43 0.001 Macaca fascicularis (crab eating macaque, ...) [mammals] taxid 9541 gi|20140689|sp|Q95M53|TLR2_MACFA Toll-like receptor 2 prec... 42 0.001 Caenorhabditis elegans [nematodes] taxid 6239 gi|17543896|ref|NP_502736.1| (NM_070335) Y64G10A.6.p [Caen... 40 0.005 Arabidopsis thaliana (mouse-ear cress, ...) [eudicots] taxid 3702 gi|15241616|ref|NP_199304.1| (NM_123859) disease resistanc... 40 0.008 Oryctolagus cuniculus (domestic rabbit, ...) [mammals] taxid 9986 gi|21429694|gb|AAM50059.1| (AY101393) toll-like receptor 2... 38 0.019 Cricetulus griseus (Chinese hamsters, ...) [mammals] taxid 10029 gi|20140897|sp|Q9R1F8|TLR2_CRIGR Toll-like receptor 2 prec... 38 0.019 Fusobacterium nucleatum subsp. nucleatum ATCC 25586 [fusobacteria] taxid 190304 gi|19704057|ref|NP_603619.1| (NC_003454) WD-repeat family ... 37 0.041 Thermosynechococcus elongatus BP-1 [cyanobacteria] taxid 197221 gi|22299003|ref|NP_682250.1| (NC_004113) serine/threonine ... 36 0.088 Rattus norvegicus (brown rat, ...) [mammals] taxid 10116 gi|20140357|sp|Q9QX05|TLR4_RAT Toll-like receptor 4 precur... 36 0.10
cellular organisms ...................................... 101 hits 27 orgs [root] . Bacteria .............................................. 9 hits 7 orgs . . Staphylococcus hominis .............................. 1 hits 1 orgs [Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus] . . Streptomyces coelicolor A3(2) ....................... 2 hits 1 orgs [Actinobacteria; Actinobacteria (class); Actinobacteridae; Actinomycetales; Streptomycineae; Streptomycetaceae; Streptomyces; Streptomyces coelicolor] . . Chlorobium tepidum TLS .............................. 1 hits 1 orgs [Bacteroidetes/Chlorobi group; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae; Chlorobium; Chlorobium tepidum] . . Cyanobacteria ....................................... 3 hits 2 orgs . . . Nostoc sp. PCC 7120 ............................... 2 hits 1 orgs [Nostocales; Nostocaceae; Nostoc] . . . Thermosynechococcus elongatus BP-1 ................ 1 hits 1 orgs [Chroococcales; Thermosynechococcus; Thermosynechococcus elongatus] . . Agrobacterium tumefaciens ........................... 1 hits 1 orgs [Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae; Rhizobium] . . Fusobacterium nucleatum subsp. nucleatum ATCC 25586 . 1 hits 1 orgs [Fusobacteria; Fusobacteria (class); Fusobacterales; Fusobacteriaceae; Fusobacterium; Fusobacterium nucleatum; Fusobacterium nucleatum subsp. nucleatum] . Eukaryota ............................................. 91 hits 19 orgs . . Bilateria ........................................... 90 hits 18 orgs [Fungi/Metazoa group; Metazoa; Eumetazoa] . . . Coelomata ......................................... 89 hits 17 orgs . . . . Euteleostomi .................................... 58 hits 9 orgs [Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi] . . . . . Amniota ....................................... 56 hits 8 orgs [Sarcopterygii; Tetrapoda] . . . . . . Eutheria .................................... 54 hits 7 orgs [Mammalia; Theria] . . . . . . . Catarrhini ................................ 31 hits 2 orgs [Primates] . . . . . . . . Homo sapiens ............................ 30 hits 1 orgs [Hominidae; Homo/Pan/Gorilla group; Homo] . . . . . . . . Macaca fascicularis ..................... 1 hits 1 orgs [Cercopithecidae; Cercopithecinae; Macaca] . . . . . . . Muridae ................................... 20 hits 3 orgs [Rodentia; Sciurognathi] . . . . . . . . Murinae ................................. 19 hits 2 orgs . . . . . . . . . Mus musculus .......................... 18 hits 1 orgs [Mus] . . . . . . . . . Rattus norvegicus ..................... 1 hits 1 orgs [Rattus] . . . . . . . . Cricetulus griseus ...................... 1 hits 1 orgs [Cricetinae; Cricetulus] . . . . . . . Bos taurus ................................ 2 hits 1 orgs [Cetartiodactyla; Ruminantia; Pecora; Bovoidea; Bovidae; Bovinae; Bos] . . . . . . . Oryctolagus cuniculus ..................... 1 hits 1 orgs [Lagomorpha; Leporidae; Oryctolagus] . . . . . . Gallus gallus ............................... 2 hits 1 orgs [Sauropsida; Sauria; Archosauria; Aves; Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus] . . . . . Danio rerio ................................... 2 hits 1 orgs [Actinopterygii; Actinopteri; Neopterygii; Teleostei; Elopocephala; Clupeocephala; Otocephala; Ostariophysi; Otophysi; Cypriniphysi; Cypriniformes; Cyprinoidea; Cyprinidae; Rasborinae; Danio] . . . . Diptera ......................................... 31 hits 8 orgs [Protostomia; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota; Neoptera; Endopterygota] . . . . . Culicidae ..................................... 17 hits 3 orgs [Nematocera; Culicimorpha; Culicoidea] . . . . . . Aedes aegypti ............................... 5 hits 1 orgs [Culicinae; Culicini; Aedes; Stegomyia] . . . . . . Anopheles gambiae ........................... 12 hits 2 orgs [Anophelinae; Anopheles; Cellia; Pyretophorus; gambiae species complex] . . . . . . . Anopheles gambiae str. PEST ............... 6 hits 1 orgs . . . . . Schizophora ................................... 14 hits 5 orgs [Brachycera; Muscomorpha] . . . . . . Drosophila .................................. 13 hits 4 orgs [Acalyptratae; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophilina; Drosophiliti] . . . . . . . Sophophora ................................ 12 hits 3 orgs . . . . . . . . Drosophila pseudoobscura ................ 1 hits 1 orgs [obscura group; pseudoobscura subgroup] . . . . . . . . melanogaster subgroup ................... 11 hits 2 orgs [melanogaster group] . . . . . . . . . Drosophila melanogaster ............... 9 hits 1 orgs . . . . . . . . . Drosophila simulans ................... 2 hits 1 orgs . . . . . . . Drosophila virilis ........................ 1 hits 1 orgs [Drosophila; virilis group] . . . . . . Glossina palpalis palpalis .................. 1 hits 1 orgs [Calyptratae; Hippoboscoidea; Glossinidae; Glossina; Nemorhina; Glossina palpalis] . . . Caenorhabditis elegans ............................ 1 hits 1 orgs [Pseudocoelomata; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis] . . Arabidopsis thaliana ................................ 1 hits 1 orgs [Viridiplantae; Streptophyta; Charophyta/Embryophyta group; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicots; Rosidae; eurosids II; Brassicales; Brassicaceae; Arabidopsis] . Methanosarcina mazei Goe1 ............................. 1 hits 1 orgs [Archaea; Euryarchaeota; Methanococci; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina mazei]