BLASTP 2.2.6 [Apr-09-2003]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

RID: 1057255611-023940-20381

Query= PCAP_HUMAN
         (128 letters)


Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF 
           1,463,011 sequences; 469,658,079 total letters

 
If you have any problems or questions with the results of this search 
please refer to the BLAST FAQs



Results of PSI-Blast iteration 5

Skip to the first new sequence

Legend:
 - means that the alignment score was below the threshold on the previous iteration 
 - means that the alignment was checked on the previous iteration 


Hit list size 
Sequences with E-value BETTER than threshold
Related Structures
                                                                     Score    E
Sequences producing significant alignments:                          (bits) Value


 gi|21312134|ref|NP_056973.2|  positive cofactor 2, glutamine/Q-ri...   198   1e-50 

 gi|14276857|gb|AAK58423.1|AF328769_1  PC2-glutamine-rich-associat...   198   1e-50 

 gi|21748618|dbj|BAC03446.1|  FLJ00386 protein [Homo sapiens]           197   3e-50 

 gi|27734440|sp|Q96RN5|PCAP_HUMAN  Positive cofactor 2 glutamine/Q...   197   3e-50 

 gi|20177999|sp|Q924H2|PCAP_MOUSE  Positive cofactor 2 glutamine/Q...   185   1e-46 

 gi|15809028|ref|NP_291087.1|  positive cofactor 2, glutamine/Q-ri...   180   3e-45 

 gi|28374176|gb|AAH46263.1|  Similar to PC2 (positive cofactor 2, ...   162   1e-39 

 gi|28279616|gb|AAH45472.1|  Similar to PC2 (positive cofactor 2, ...   149   1e-35 

 gi|21956190|gb|AAM83255.1|AF378334_1  ARC105 [Xenopus laevis]          147   3e-35 

 gi|3037135|gb|AAC12944.1|  TPA inducible protein [Homo sapiens]        146   5e-35 

 gi|20891927|ref|XP_147188.1|  positive cofactor 2, multiprotein c...   139   1e-32 

 gi|25148756|ref|NP_741152.1|  Putative nuclear protein, nematode ...   131   2e-30 

 gi|25148761|ref|NP_741151.1|  Putative nuclear protein, nematode ...   128   2e-29 

 gi|631119|pir||S39162  transcription coactivator CREB-binding pro...   112   1e-24 

 gi|4758056|ref|NP_004371.1|  CREB binding protein [Homo sapiens] ...   112   1e-24 

 gi|4321116|gb|AAC51331.2|  CREB-binding protein [Homo sapiens]         112   1e-24 

 gi|19920468|ref|NP_608528.1|  CG4184-PA [Drosophila melanogaster]...   111   3e-24 

 gi|19547885|gb|AAL87531.1|  CREB-binding protein [Mus musculus] >...   107   4e-23 

 gi|1345703|sp|P45481|CBP_MOUSE  CREB-binding protein >gi|481698|p...   106   5e-23 

 gi|737920|prf||1923401A  protein CBP                                   106   5e-23 

 gi|2996629|gb|AAC08447.1|  CBP [Homo sapiens]                          106   6e-23 

 gi|7506661|pir||T16726  hypothetical protein R12B2.5 - Caenorhabd...   103   6e-22 

 gi|17567279|ref|NP_509376.1|  KIX domain containing protein famil...    96   1e-19 

 gi|4139873|pdb|1KDX|A  Chain A, Kix Domain Of Mouse Cbp (Creb Bin...    83   6e-16 

 gi|31753089|gb|AAH53889.1|  Unknown (protein for IMAGE:6151364) [...    83   6e-16 

 gi|27881767|gb|AAH44677.1|  Similar to CREB binding protein (Rubi...    83   1e-15 

 gi|27666550|ref|XP_235770.1|  similar to E1A-associated protein p...    82   1e-15 

 gi|4557557|ref|NP_001420.1|  E1A binding protein p300; E1A-bindin...    81   2e-15 

 gi|547239|gb|AAB31182.1|  p300=transcription coactivator {N-termi...    79   1e-14 

 gi|27663074|ref|XP_235502.1|  similar to E1A-associated protein p...    79   1e-14 

 gi|28486616|ref|XP_283295.1|  similar to E1A-associated protein p...    77   5e-14 

 gi|21307831|gb|AAL54859.1|  CREB-binding protein [Aplysia califor...    74   4e-13 

 gi|2133462|pir||S60123  hypothetical protein R10E11.1 - Caenorhab...    72   1e-12 

 gi|17552710|ref|NP_499160.1|  CBP/p300 homolog CBP-1 (cbp-1) [Cae...    72   2e-12 

 gi|17552708|ref|NP_499161.1|  CBP/p300 homolog CBP-1 (cbp-1) [Cae...    72   2e-12 

 gi|31204369|ref|XP_311133.1|  ENSANGP00000004748 [Anopheles gambi...    69   9e-12 

 gi|7511830|pir||T13828  CREB-binding protein homolog - fruit fly ...    67   5e-11 

 gi|24640865|ref|NP_524642.2|  nejire CG15319-PB [Drosophila melan...    66   1e-10 

 gi|482238|pir||S41033  hypothetical protein K03H1.10 - Caenorhabd...    62   2e-09 

 gi|17554044|ref|NP_499201.1|  TAZ zinc finger and KIX domain cont...    61   2e-09 

 gi|24461867|gb|AAN62354.1|AF506028_23  CTV.22 [Poncirus trifoliata]     43   0.001 


Sequences with E-value WORSE than threshold


 gi|24461860|gb|AAN62347.1|AF506028_14  CTV.20 [Poncirus trifoliata]     40   0.006 

 gi|17508323|ref|NP_493339.1|  KIX domain containing protein famil...    39   0.009 

 gi|28917231|gb|EAA26944.1|  hypothetical protein [Neurospora crassa]    38   0.028 

 gi|19570247|dbj|BAB86283.1|  kinesin-like protein NACK1 [Nicotian...    36   0.13  

 gi|17539958|ref|NP_501507.1|  Signal recognition particle (55.0 k...    35   0.20  


Alignments








>gi|21312134|ref|NP_056973.2|   positive cofactor 2, glutamine/Q-rich-associated protein; TPA
           inducible protein; TPA inducible gene-1;
           PC2-glutamine-rich-associated protein; trinucleotide
           repeat containing 7 [Homo sapiens]
 gi|15559260|gb|AAH13985.1|AAH13985   PC2 (positive cofactor 2, multiprotein complex)
           glutamine/Q-rich-associated protein [Homo sapiens]
          Length = 748

 Score =  198 bits (505), Expect = 1e-50
 Identities = 128/128 (100%), Positives = 128/128 (100%)

Query: 1   MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
           MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 1   MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60

Query: 61  RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120
           RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG
Sbjct: 61  RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120

Query: 121 QPMSLSGQ 128
           QPMSLSGQ
Sbjct: 121 QPMSLSGQ 128



>gi|14276857|gb|AAK58423.1|AF328769_1   PC2-glutamine-rich-associated protein [Homo sapiens]
          Length = 746

 Score =  198 bits (505), Expect = 1e-50
 Identities = 128/128 (100%), Positives = 128/128 (100%)

Query: 1   MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
           MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 1   MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60

Query: 61  RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120
           RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG
Sbjct: 61  RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120

Query: 121 QPMSLSGQ 128
           QPMSLSGQ
Sbjct: 121 QPMSLSGQ 128



>gi|21748618|dbj|BAC03446.1|   FLJ00386 protein [Homo sapiens]
          Length = 811

 Score =  197 bits (502), Expect = 3e-50
 Identities = 128/128 (100%), Positives = 128/128 (100%)

Query: 1   MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
           MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 24  MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 83

Query: 61  RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120
           RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG
Sbjct: 84  RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 143

Query: 121 QPMSLSGQ 128
           QPMSLSGQ
Sbjct: 144 QPMSLSGQ 151



>gi|27734440|sp|Q96RN5|PCAP_HUMAN   Positive cofactor 2 glutamine/Q-rich-associated protein (PC2
           glutamine/Q-rich-associated protein) (TPA-inducible
           gene-1) (TIG-1) (Activator-recruited cofactor 105 kDa
           component) (ARC105) (CTG repeat protein 7a)
          Length = 788

 Score =  197 bits (501), Expect = 3e-50
 Identities = 128/128 (100%), Positives = 128/128 (100%)

Query: 1   MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
           MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 1   MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60

Query: 61  RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120
           RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG
Sbjct: 61  RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120

Query: 121 QPMSLSGQ 128
           QPMSLSGQ
Sbjct: 121 QPMSLSGQ 128



>gi|20177999|sp|Q924H2|PCAP_MOUSE   Positive cofactor 2 glutamine/Q-rich-associated protein (PC2
           glutamine/Q-rich-associated protein) (mPcqap)
          Length = 792

 Score =  185 bits (470), Expect = 1e-46
 Identities = 120/128 (93%), Positives = 121/128 (94%)

Query: 1   MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
           MDV GQETDWRS AFR KLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 1   MDVWGQETDWRSAAFRLKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60

Query: 61  RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120
           RLIIHFRDIHNKKSQASVSDPMNALQSLTGGP  GAAGIGMPPRGPGQSLGGMG LGAMG
Sbjct: 61  RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPTPGAAGIGMPPRGPGQSLGGMGGLGAMG 120

Query: 121 QPMSLSGQ 128
           QP+ LSGQ
Sbjct: 121 QPLPLSGQ 128



>gi|15809028|ref|NP_291087.1|   positive cofactor 2, glutamine/Q-rich-associated protein [Mus
           musculus]
 gi|14276859|gb|AAK58424.1|AF328770_1   PC2-glutamine-rich-associated protein [Mus musculus]
          Length = 667

 Score =  180 bits (458), Expect = 3e-45
 Identities = 120/128 (93%), Positives = 121/128 (94%)

Query: 1   MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
           MDV GQETDWRS AFR KLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 1   MDVWGQETDWRSAAFRLKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60

Query: 61  RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMG 120
           RLIIHFRDIHNKKSQASVSDPMNALQSLTGGP  GAAGIGMPPRGPGQSLGGMG LGAMG
Sbjct: 61  RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPTPGAAGIGMPPRGPGQSLGGMGGLGAMG 120

Query: 121 QPMSLSGQ 128
           QP+ LSGQ
Sbjct: 121 QPLPLSGQ 128



>gi|28374176|gb|AAH46263.1|   Similar to PC2 (positive cofactor 2, multiprotein complex)
           glutamine/Q-rich-associated protein [Xenopus laevis]
          Length = 846

 Score =  162 bits (410), Expect = 1e-39
 Identities = 77/112 (68%), Positives = 90/112 (80%)

Query: 17  QKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQA 76
           QKLVSQI++AMRKAGVAH+KSSK+MESHVFLKAKTR+EYLSLVARLIIHFRDI NKK+Q 
Sbjct: 1   QKLVSQIDEAMRKAGVAHTKSSKEMESHVFLKAKTREEYLSLVARLIIHFRDIFNKKNQT 60

Query: 77  SVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQ 128
           + SDPMNALQ+LTG    G  G+GM  R  G  +G MG +  + Q M+L GQ
Sbjct: 61  AASDPMNALQNLTGNAVVGGQGMGMGVRPQGAQMGAMGGMTQIAQQMNLPGQ 112



>gi|28279616|gb|AAH45472.1|   Similar to PC2 (positive cofactor 2, multiprotein complex)
           glutamine/Q-rich-associated protein [Danio rerio]
          Length = 809

 Score =  149 bits (376), Expect = 1e-35
 Identities = 69/108 (63%), Positives = 82/108 (75%), Gaps = 7/108 (6%)

Query: 1   MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
           MDV G ++DWRS AFRQK+V+QIE+AMRKAG  H+KSS +MESHVF KAKTR+EYLS+VA
Sbjct: 1   MDVPGPDSDWRSPAFRQKVVAQIEEAMRKAGTGHTKSSTEMESHVFTKAKTREEYLSMVA 60

Query: 61  RLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQ 108
           RLIIHFRDIH KK+Q    DP+NALQ+L      G     + PR PG 
Sbjct: 61  RLIIHFRDIH-KKAQGG-PDPINALQNL-----PGGVPGVIGPRPPGA 101



>gi|21956190|gb|AAM83255.1|AF378334_1   ARC105 [Xenopus laevis]
          Length = 754

 Score =  147 bits (371), Expect = 3e-35
 Identities = 71/102 (69%), Positives = 80/102 (78%)

Query: 27  MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQ 86
           MRKAGVAH+KSSKDMESHVFLKAKTR+EYLSLVARLIIHFRDI NKKSQA+ +DPMNALQ
Sbjct: 1   MRKAGVAHTKSSKDMESHVFLKAKTREEYLSLVARLIIHFRDILNKKSQAAATDPMNALQ 60

Query: 87  SLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQ 128
           +LTG    G  G+GM  R  G  +G M  +  M Q M+L GQ
Sbjct: 61  NLTGTAVVGGQGMGMGVRPQGAQMGAMSGMAQMAQQMNLPGQ 102



>gi|3037135|gb|AAC12944.1|   TPA inducible protein [Homo sapiens]
          Length = 579

 Score =  146 bits (370), Expect = 5e-35
 Identities = 101/102 (99%), Positives = 101/102 (99%)

Query: 27  MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQ 86
           MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQ
Sbjct: 1   MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQ 60

Query: 87  SLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQ 128
           SLTGGPAAGAAGIGMPPRGPGQSLGGMGS GAMGQPMSLSGQ
Sbjct: 61  SLTGGPAAGAAGIGMPPRGPGQSLGGMGSFGAMGQPMSLSGQ 102



>gi|20891927|ref|XP_147188.1|   positive cofactor 2, multiprotein complex,
           glutamine/Q-rich-associated protein [Mus musculus]
          Length = 763

 Score =  139 bits (350), Expect = 1e-32
 Identities = 97/102 (95%), Positives = 98/102 (96%)

Query: 27  MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQ 86
           MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQ
Sbjct: 1   MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQ 60

Query: 87  SLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQ 128
           SLTGGP  GAAGIGMPPRGPGQSLGGMG LGAMGQP+ LSGQ
Sbjct: 61  SLTGGPTPGAAGIGMPPRGPGQSLGGMGGLGAMGQPLPLSGQ 102



>gi|25148756|ref|NP_741152.1|   Putative nuclear protein, nematode specific [Caenorhabditis
           elegans]
 gi|21363104|sp|Q21955|YNL5_CAEEL   Hypothetical protein R12B2.5 in chromosome III
 gi|17976542|gb|AAA50743.3|   Hypothetical protein R12B2.5a [Caenorhabditis elegans]
          Length = 780

 Score =  131 bits (330), Expect = 2e-30
 Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 17/117 (14%)

Query: 7   ETDWRSTAFRQKLVSQIEDAMRKAGVAHSK-----SSKDMESHVFLKAKTRDEYLSLVAR 61
           E DW S  FR+ ++ ++E  + +             ++ +E +VF K  ++DEY+  +A+
Sbjct: 3   EEDWPSPKFREHVIQRLEPELARNRQNAPNLPVPGDARQVEEYVFAKCMSKDEYMRTIAK 62

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQ---------SLTGGPAAGAAGIGMPPRGPGQS 109
           +I     I+     A+V   +   Q         +L G   AG       P  P   
Sbjct: 63  VI---NAINCNSKSAAVPSVLQPSQFHSPPCTTAALLGNTPAGGTPGYRAPVPPDPQ 116



>gi|25148761|ref|NP_741151.1|   Putative nuclear protein, nematode specific [Caenorhabditis
           elegans]
 gi|21450526|gb|AAM54164.1|U00066_6   Hypothetical protein R12B2.5b [Caenorhabditis elegans]
          Length = 777

 Score =  128 bits (321), Expect = 2e-29
 Identities = 25/114 (21%), Positives = 46/114 (40%), Gaps = 14/114 (12%)

Query: 7   ETDWRSTAFRQKLVSQIEDAMRKAGVAHSK-----SSKDMESHVFLKAKTRDEYLSLVAR 61
           E DW S  FR+ ++ ++E  + +             ++ +E +VF K  ++DEY+  +A+
Sbjct: 3   EEDWPSPKFREHVIQRLEPELARNRQNAPNLPVPGDARQVEEYVFAKCMSKDEYMRTIAK 62

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQ------SLTGGPAAGAAGIGMPPRGPGQS 109
           +I     I+     A+V   +   Q      +  G   AG       P  P   
Sbjct: 63  VI---NAINCNSKSAAVPSVLQPSQFHSPPCTTAGNTPAGGTPGYRAPVPPDPQ 113



>gi|631119|pir||S39162   transcription coactivator CREB-binding protein - human
          Length = 2440

 Score =  112 bits (280), Expect = 1e-24
 Identities = 24/108 (22%), Positives = 40/108 (37%), Gaps = 15/108 (13%)

Query: 12  STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEYLSLVAR 61
           +   R  LV ++  A+      A  K          +K +E  ++  A +RDEY  L+A 
Sbjct: 597 TQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAE 656

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQS 109
            I   +    +K ++ +       Q + G   A  A    PP  P   
Sbjct: 657 KIYKIQKELEEKRRSRLHK-----QGILGNQPALPAPGAQPPVIPQAQ 699



>gi|4758056|ref|NP_004371.1|   CREB binding protein [Homo sapiens]
 gi|3023440|sp|Q92793|CBP_HUMAN   CREB-binding protein
 gi|2443859|gb|AAC51770.1|   CREB-binding protein
          Length = 2442

 Score =  112 bits (280), Expect = 1e-24
 Identities = 24/108 (22%), Positives = 40/108 (37%), Gaps = 15/108 (13%)

Query: 12  STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEYLSLVAR 61
           +   R  LV ++  A+      A  K          +K +E  ++  A +RDEY  L+A 
Sbjct: 597 TQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAE 656

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQS 109
            I   +    +K ++ +       Q + G   A  A    PP  P   
Sbjct: 657 KIYKIQKELEEKRRSRLHK-----QGILGNQPALPAPGAQPPVIPQAQ 699



>gi|4321116|gb|AAC51331.2|   CREB-binding protein [Homo sapiens]
          Length = 2442

 Score =  112 bits (280), Expect = 1e-24
 Identities = 24/108 (22%), Positives = 40/108 (37%), Gaps = 15/108 (13%)

Query: 12  STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEYLSLVAR 61
           +   R  LV ++  A+      A  K          +K +E  ++  A +RDEY  L+A 
Sbjct: 597 TQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAE 656

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQS 109
            I   +    +K ++ +       Q + G   A  A    PP  P   
Sbjct: 657 KIYKIQKELEEKRRSRLHK-----QGILGNQPALPAPGAQPPVIPQAQ 699



>gi|19920468|ref|NP_608528.1|   CG4184-PA [Drosophila melanogaster]
 gi|5052530|gb|AAD38595.1|AF145620_1   BcDNA.GH03922 [Drosophila melanogaster]
 gi|7296198|gb|AAF51490.1|   CG4184-PA [Drosophila melanogaster]
          Length = 749

 Score =  111 bits (277), Expect = 3e-24
 Identities = 36/115 (31%), Positives = 58/115 (50%), Gaps = 23/115 (20%)

Query: 8   TDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFR 67
            DW+S  FRQ ++S+I D +       +K++  ME+H+F K++T+DEYL LVA+L +H++
Sbjct: 3   EDWQSQKFRQNVISKIHDLLPPNAQDQTKNAGVMENHIFRKSRTKDEYLGLVAKLFMHYK 62

Query: 68  DIHNKK---------------------SQASVSDPMNALQSLT--GGPAAGAAGI 99
           D+  K                       Q  + DP+NALQ+L   G        +
Sbjct: 63  DMSRKSQQQQQQQQQQGGPPPNAEMGGGQNMMQDPLNALQNLASQGNRNPQMMPM 117



>gi|19547885|gb|AAL87531.1|   CREB-binding protein [Mus musculus]
 gi|19547887|gb|AAL87532.1|   CREB-binding protein [Mus musculus]
          Length = 2429

 Score =  107 bits (267), Expect = 4e-23
 Identities = 24/108 (22%), Positives = 40/108 (37%), Gaps = 15/108 (13%)

Query: 12  STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEYLSLVAR 61
           +   R  LV ++  A+      A  K          +K +E  ++  A +RDEY  L+A 
Sbjct: 590 TQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAE 649

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQS 109
            I   +    +K ++ +       Q + G   A  A    PP  P   
Sbjct: 650 KIYKIQKELEEKRRSRLHK-----QGILGNQPALPASGAQPPVIPPAQ 692



>gi|1345703|sp|P45481|CBP_MOUSE   CREB-binding protein
 gi|481698|pir||S39161   CREB-binding protein - mouse
 gi|435855|gb|AAB28651.1|   CREB-binding protein; CBP [Mus sp.]
          Length = 2441

 Score =  106 bits (266), Expect = 5e-23
 Identities = 24/108 (22%), Positives = 39/108 (36%), Gaps = 15/108 (13%)

Query: 12  STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEYLSLVAR 61
           +   R  LV ++  A+      A  K          +K +E  ++  A +RDEY  L+A 
Sbjct: 596 TQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAE 655

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQS 109
            I   +    +K +  +       Q + G   A  A    PP  P   
Sbjct: 656 KIYKIQKELEEKRRTRLHK-----QGILGNQPALPASGAQPPVIPPAQ 698



>gi|737920|prf||1923401A   protein CBP
          Length = 2441

 Score =  106 bits (266), Expect = 5e-23
 Identities = 24/108 (22%), Positives = 39/108 (36%), Gaps = 15/108 (13%)

Query: 12  STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEYLSLVAR 61
           +   R  LV ++  A+      A  K          +K +E  ++  A +RDEY  L+A 
Sbjct: 596 TQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAE 655

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQS 109
            I   +    +K +  +       Q + G   A  A    PP  P   
Sbjct: 656 KIYKIQKELEEKRRTRLHK-----QGILGNQPALPASGAQPPVIPPAQ 698



>gi|2996629|gb|AAC08447.1|   CBP [Homo sapiens]
          Length = 555

 Score =  106 bits (265), Expect = 6e-23
 Identities = 24/108 (22%), Positives = 40/108 (37%), Gaps = 15/108 (13%)

Query: 12  STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEYLSLVAR 61
           +   R  LV ++  A+      A  K          +K +E  ++  A +RDEY  L+A 
Sbjct: 331 TQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAE 390

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQS 109
            I   +    +K ++ +       Q + G   A  A    PP  P   
Sbjct: 391 KIYKIQKELEEKRRSRLHK-----QGILGNQPALPAPGAQPPVIPQAQ 433



>gi|7506661|pir||T16726   hypothetical protein R12B2.5 - Caenorhabditis elegans
          Length = 760

 Score =  103 bits (257), Expect = 6e-22
 Identities = 20/85 (23%), Positives = 40/85 (47%), Gaps = 8/85 (9%)

Query: 7  ETDWRSTAFRQKLVSQIEDAMRKAGVAHSK-----SSKDMESHVFLKAKTRDEYLSLVAR 61
          E DW S  FR+ ++ ++E  + +             ++ +E +VF K  ++DEY+  +A+
Sbjct: 3  EEDWPSPKFREHVIQRLEPELARNRQNAPNLPVPGDARQVEEYVFAKCMSKDEYMRTIAK 62

Query: 62 LIIHFRDIHNKKSQASVSDPMNALQ 86
          +I     I+     A+V   +   Q
Sbjct: 63 VI---NAINCNSKSAAVPSVLQPSQ 84



>gi|17567279|ref|NP_509376.1|   KIX domain containing protein family member [Caenorhabditis
           elegans]
 gi|7499689|pir||T16139   hypothetical protein F22F1.3 - Caenorhabditis elegans
 gi|1118044|gb|AAA83283.1|   Hypothetical protein F22F1.3 [Caenorhabditis elegans]
          Length = 295

 Score = 95.7 bits (237), Expect = 1e-19
 Identities = 18/77 (23%), Positives = 36/77 (46%), Gaps = 10/77 (12%)

Query: 15  FRQKLVSQI-EDAMRKAGVAHSKSSKD---------MESHVFLKAKTRDEYLSLVARLII 64
            RQ ++++I  +A+ +        ++          ME   F K +T+DEY + +AR+I+
Sbjct: 70  LRQYMITKIVREAVPRPNSDAKNDARMIELKEYATFMEKKSFEKVQTKDEYYAELARIIL 129

Query: 65  HFRDIHNKKSQASVSDP 81
             +     + + S  DP
Sbjct: 130 SMQKHLQSRPKGSYEDP 146



>gi|4139873|pdb|1KDX|A   Chain A, Kix Domain Of Mouse Cbp (Creb Binding Protein) In
          Complex With Phosphorylated Kinase Inducible Domain
          (Pkid) Of Rat Creb (Cyclic Amp Response Element Binding
          Protein), Nmr 17 Structures
          Length = 81

 Score = 83.3 bits (205), Expect = 6e-16
 Identities = 16/71 (22%), Positives = 28/71 (39%), Gaps = 10/71 (14%)

Query: 12 STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEYLSLVAR 61
          +   R  LV ++  A+      A  K          +K +E  ++  A +RDEY  L+A 
Sbjct: 11 TQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAE 70

Query: 62 LIIHFRDIHNK 72
           I   +    +
Sbjct: 71 KIYKIQKELEE 81



>gi|31753089|gb|AAH53889.1|   Unknown (protein for IMAGE:6151364) [Homo sapiens]
          Length = 1553

 Score = 83.3 bits (205), Expect = 6e-16
 Identities = 28/127 (22%), Positives = 47/127 (37%), Gaps = 17/127 (13%)

Query: 12  STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEYLSLVAR 61
           +   R  LV ++  A+      A  K          ++ +E  ++  A  R EY  L+A 
Sbjct: 576 TQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAE 635

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGP-GQSLGGMGSLGAMG 120
            I   +    +K +  +       Q++     AG   + M P    GQ   GM S G + 
Sbjct: 636 KIYKIQKELEEKRRTRLQK-----QNMLPNA-AGMVPVSMNPGPNMGQPQPGMTSNGPLP 689

Query: 121 QPMSLSG 127
            P  + G
Sbjct: 690 DPSMIRG 696



>gi|27881767|gb|AAH44677.1|   Similar to CREB binding protein (Rubinstein-Taybi syndrome)
           [Xenopus laevis]
          Length = 1047

 Score = 82.6 bits (203), Expect = 1e-15
 Identities = 19/101 (18%), Positives = 36/101 (35%), Gaps = 15/101 (14%)

Query: 12  STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEYLSLVAR 61
           +   R  LV ++  A+      A  K          ++ +E  ++  A +RDEY   +A 
Sbjct: 586 TQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANSRDEYYHFLAE 645

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMP 102
            I   +    +K ++ +       Q +    A   A    P
Sbjct: 646 KIYKIQKELEEKRRSRLQK-----QGIMSSQAPLQAPGAQP 681



>gi|27666550|ref|XP_235770.1|   similar to E1A-associated protein p300 [Rattus norvegicus]
          Length = 1605

 Score = 82.2 bits (202), Expect = 1e-15
 Identities = 21/113 (18%), Positives = 38/113 (33%), Gaps = 17/113 (15%)

Query: 12  STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEYLSLVAR 61
           +   R  LV ++  A+      A  K          ++ +E  ++  A  R EY  L+A 
Sbjct: 205 TQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAE 264

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAG-AAGIGMPPRGPGQSLGGM 113
            I   +    +K +  +       Q++           +   P   GQ   GM
Sbjct: 265 KIYKIQKELEEKRRTRLQK-----QNMLPSAPGMVPVPMNTAPNM-GQQPTGM 311



>gi|4557557|ref|NP_001420.1|   E1A binding protein p300; E1A-binding protein, 300kD [Homo sapiens]
 gi|3024341|sp|Q09472|P300_HUMAN   E1A-associated protein p300
 gi|627657|pir||A54277   transcription adaptor protein p300 - human
 gi|495301|gb|AAA18639.1|   p300 protein
          Length = 2414

 Score = 81.4 bits (200), Expect = 2e-15
 Identities = 28/127 (22%), Positives = 47/127 (37%), Gaps = 17/127 (13%)

Query: 12  STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEYLSLVAR 61
           +   R  LV ++  A+      A  K          ++ +E  ++  A  R EY  L+A 
Sbjct: 576 TQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAE 635

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGP-GQSLGGMGSLGAMG 120
            I   +    +K +  +       Q++     AG   + M P    GQ   GM S G + 
Sbjct: 636 KIYKIQKELEEKRRTRLQK-----QNMLPNA-AGMVPVSMNPGPNMGQPQPGMTSNGPLP 689

Query: 121 QPMSLSG 127
            P  + G
Sbjct: 690 DPSMIRG 696



>gi|547239|gb|AAB31182.1|   p300=transcription coactivator {N-terminal} [mice, Peptide Partial,
           688 aa]
          Length = 688

 Score = 79.1 bits (194), Expect = 1e-14
 Identities = 23/121 (19%), Positives = 40/121 (33%), Gaps = 28/121 (23%)

Query: 12  STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEYLSLVAR 61
           +   R  LV ++  A+      A  K          ++ +E  ++  A  R EY  L+A 
Sbjct: 577 TQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAE 636

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQ 121
            I   +    +K +  +       Q++           GM P         M +   MGQ
Sbjct: 637 KIYKIQKELEEKRRTRLQK-----QNMLPNAP------GMGPVP-------MNTGSNMGQ 678

Query: 122 P 122
            
Sbjct: 679 Q 679



>gi|27663074|ref|XP_235502.1|   similar to E1A-associated protein p300 [Rattus norvegicus]
          Length = 2156

 Score = 78.7 bits (193), Expect = 1e-14
 Identities = 21/113 (18%), Positives = 38/113 (33%), Gaps = 17/113 (15%)

Query: 12  STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEYLSLVAR 61
           +   R  LV ++  A+      A  K          ++ +E  ++  A  R EY  L+A 
Sbjct: 205 TQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAE 264

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAG-AAGIGMPPRGPGQSLGGM 113
            I   +    +K +  +       Q++           +   P   GQ   GM
Sbjct: 265 KIYKIQKELEEKRRTRLQK-----QNMLPSAPGMVPVPMNTAPNM-GQQPTGM 311



>gi|28486616|ref|XP_283295.1|   similar to E1A-associated protein p300 [Mus musculus]
 gi|29244384|ref|NP_808489.1|   hypothetical protein A730011L11 [Mus musculus]
 gi|26335221|dbj|BAC31311.1|   unnamed protein product [Mus musculus]
          Length = 714

 Score = 77.2 bits (189), Expect = 5e-14
 Identities = 23/121 (19%), Positives = 40/121 (33%), Gaps = 28/121 (23%)

Query: 12  STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEYLSLVAR 61
           +   R  LV ++  A+      A  K          ++ +E  ++  A  R EY  L+A 
Sbjct: 577 TQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAE 636

Query: 62  LIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQ 121
            I   +    +K +  +       Q++           GM P         M +   MGQ
Sbjct: 637 KIYKIQKELEEKRRTRLQK-----QNMLPNAP------GMGPVP-------MNTGSNMGQ 678

Query: 122 P 122
            
Sbjct: 679 Q 679



>gi|21307831|gb|AAL54859.1|   CREB-binding protein [Aplysia californica]
          Length = 2245

 Score = 74.1 bits (181), Expect = 4e-13
 Identities = 17/116 (14%), Positives = 32/116 (27%), Gaps = 22/116 (18%)

Query: 9   DWR---STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEY 55
           DW    +   R  LV ++  A+      A  +          ++ +E  ++  A  R +Y
Sbjct: 504 DWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARKVEGDMYESANNRGQY 563

Query: 56  LSLVARLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLG 111
             L+A  I   +    +K    +                           P    G
Sbjct: 564 YHLLAEKIYKIQKELEEKRIQRMK---------VQNAPNAQVPGMQGQIHPNAQNG 610



>gi|2133462|pir||S60123   hypothetical protein R10E11.1 - Caenorhabditis elegans
          Length = 2027

 Score = 72.2 bits (176), Expect = 1e-12
 Identities = 30/157 (19%), Positives = 53/157 (33%), Gaps = 31/157 (19%)

Query: 2   DVSGQETDWRST---AFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLK 48
           D+     +W        R  LV ++  A+  +                 ++ +E  +F  
Sbjct: 590 DMPDCTKEWHHQVTKDLRNHLVGKLVKAIFPEPNQEAMNDNRLKDLIAYARKVEKEMFES 649

Query: 49  AKTRDEYLSLVARLIIHFRDIHNKKSQ------ASVSD-----PMNALQSLTG------G 91
           A  R+EY  L+A  I   +    +K        A+  D     P N L  + G       
Sbjct: 650 ANDREEYYHLLAEKIYKIQKELQEKKNSRLNQGAAAHDQYAIPPSNELAQMLGVEGGRSD 709

Query: 92  PAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQ 128
             +  + + + P    Q  GG  +   M Q +  +GQ
Sbjct: 710 VHSEGSSMAVAPSQQNQPWGGAPN-SNMHQQIPPNGQ 745



>gi|17552710|ref|NP_499160.1|   CBP/p300 homolog CBP-1 (cbp-1) [Caenorhabditis elegans]
 gi|20455476|sp|P34545|CBP1_CAEEL   Protein cbp-1
 gi|25299632|pir||G88564   protein R10E11.1 [imported] - Caenorhabditis elegans
 gi|17645979|emb|CAD18875.1|   C. elegans CBP-1 protein (corresponding sequence R10E11.1b)
           [Caenorhabditis elegans]
          Length = 2056

 Score = 72.2 bits (176), Expect = 2e-12
 Identities = 30/157 (19%), Positives = 53/157 (33%), Gaps = 31/157 (19%)

Query: 2   DVSGQETDWRST---AFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLK 48
           D+     +W        R  LV ++  A+  +                 ++ +E  +F  
Sbjct: 590 DMPDCTKEWHHQVTKDLRNHLVGKLVKAIFPEPNQEAMNDNRLKDLIAYARKVEKEMFES 649

Query: 49  AKTRDEYLSLVARLIIHFRDIHNKKSQ------ASVSD-----PMNALQSLTG------G 91
           A  R+EY  L+A  I   +    +K        A+  D     P N L  + G       
Sbjct: 650 ANDREEYYHLLAEKIYKIQKELQEKKNSRLNQGAAAHDQYAIPPSNELAQMLGVEGGRSD 709

Query: 92  PAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQ 128
             +  + + + P    Q  GG  +   M Q +  +GQ
Sbjct: 710 VHSEGSSMAVAPSQQNQPWGGAPN-SNMHQQIPPNGQ 745



>gi|17552708|ref|NP_499161.1|   CBP/p300 homolog CBP-1 (cbp-1) [Caenorhabditis elegans]
 gi|14530537|emb|CAA82353.2|   C. elegans CBP-1 protein (corresponding sequence R10E11.1a)
           [Caenorhabditis elegans]
          Length = 2045

 Score = 72.2 bits (176), Expect = 2e-12
 Identities = 30/157 (19%), Positives = 53/157 (33%), Gaps = 31/157 (19%)

Query: 2   DVSGQETDWRST---AFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLK 48
           D+     +W        R  LV ++  A+  +                 ++ +E  +F  
Sbjct: 579 DMPDCTKEWHHQVTKDLRNHLVGKLVKAIFPEPNQEAMNDNRLKDLIAYARKVEKEMFES 638

Query: 49  AKTRDEYLSLVARLIIHFRDIHNKKSQ------ASVSD-----PMNALQSLTG------G 91
           A  R+EY  L+A  I   +    +K        A+  D     P N L  + G       
Sbjct: 639 ANDREEYYHLLAEKIYKIQKELQEKKNSRLNQGAAAHDQYAIPPSNELAQMLGVEGGRSD 698

Query: 92  PAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQ 128
             +  + + + P    Q  GG  +   M Q +  +GQ
Sbjct: 699 VHSEGSSMAVAPSQQNQPWGGAPN-SNMHQQIPPNGQ 734



>gi|31204369|ref|XP_311133.1|   ENSANGP00000004748 [Anopheles gambiae]
 gi|30178093|gb|EAA06516.2|   ENSANGP00000004748 [Anopheles gambiae str. PEST]
          Length = 2572

 Score = 69.5 bits (169), Expect = 9e-12
 Identities = 17/82 (20%), Positives = 30/82 (36%), Gaps = 13/82 (15%)

Query: 9   DWR---STAFRQKLVSQIEDAM-RKAGVAHSKS---------SKDMESHVFLKAKTRDEY 55
           DW    +   R  LV ++  A+      +             +K +E  ++  A +R EY
Sbjct: 744 DWHHSVTPDLRNHLVHKLVQAIFPSPDPSAMFDKRMYNLVAYAKKVEGDMYEMANSRSEY 803

Query: 56  LSLVARLIIHFRDIHNKKSQAS 77
             L+A  I   +    +K Q  
Sbjct: 804 YHLLAEKIYKIQKELEEKRQKR 825



>gi|7511830|pir||T13828   CREB-binding protein homolog - fruit fly (Drosophila melanogaster)
 gi|1916930|gb|AAB53050.1|   CREB-binding protein homolog [Drosophila melanogaster]
          Length = 3190

 Score = 67.2 bits (163), Expect = 5e-11
 Identities = 18/81 (22%), Positives = 32/81 (39%), Gaps = 13/81 (16%)

Query: 7    ETDWR---STAFRQKLVSQIEDAM-RKAGVAHSKSSKD---------MESHVFLKAKTRD 53
            E DWR   +   R  LV ++  A+   +     +  +          +E  ++  AK+R 
Sbjct: 940  EKDWRESVTADLRNHLVHKLVQAIFPTSDPTTMQDKRMHNLVSYAEKVEKDMYEMAKSRS 999

Query: 54   EYLSLVARLIIHFRDIHNKKS 74
            EY  L+A  I   +    +K 
Sbjct: 1000 EYYHLLAEKIYKIQKELEEKR 1020



>gi|24640865|ref|NP_524642.2|   nejire CG15319-PB [Drosophila melanogaster]
 gi|22833041|gb|AAF46516.2|   CG15319-PB [Drosophila melanogaster]
          Length = 3276

 Score = 66.0 bits (160), Expect = 1e-10
 Identities = 18/81 (22%), Positives = 32/81 (39%), Gaps = 13/81 (16%)

Query: 7    ETDWR---STAFRQKLVSQIEDAM-RKAGVAHSKSSKD---------MESHVFLKAKTRD 53
            E DWR   +   R  LV ++  A+   +     +  +          +E  ++  AK+R 
Sbjct: 940  EKDWRESVTADLRNHLVHKLVQAIFPTSDPTTMQDKRMHNLVSYAEKVEKDMYEMAKSRS 999

Query: 54   EYLSLVARLIIHFRDIHNKKS 74
            EY  L+A  I   +    +K 
Sbjct: 1000 EYYHLLAEKIYKIQKELEEKR 1020



>gi|482238|pir||S41033   hypothetical protein K03H1.10 - Caenorhabditis elegans  (fragment)
          Length = 316

 Score = 62.2 bits (150), Expect = 2e-09
 Identities = 17/98 (17%), Positives = 32/98 (32%), Gaps = 18/98 (18%)

Query: 2   DVSGQETDWRST---AFRQKLVSQIEDAMRKAGVAHSKS---------SKDMESHVFLKA 49
           +V  +  +W        R  +V ++  A+                   ++ +E  VF  A
Sbjct: 155 NVPVRTKEWHRQVTNDLRNHIVGKLVKAIC-PAPEMMNDIRLKDLNAYARKVEKEVFETA 213

Query: 50  KTRDEYLSLVARLIIHFRDIHNKKS-----QASVSDPM 82
             R  Y  L+A  I   +    +K      Q +   P+
Sbjct: 214 IDRKNYYHLLAEKIYEIQKELQEKKNSRLNQGAAQSPL 251



>gi|17554044|ref|NP_499201.1|   TAZ zinc finger and KIX domain containing protein family member
           (36.7 kD) [Caenorhabditis elegans]
 gi|25395947|pir||D88569   protein K03H1.10 [imported] - Caenorhabditis elegans
 gi|3877003|emb|CAA82940.1|   Hypothetical protein K03H1.10 [Caenorhabditis elegans]
 gi|3878179|emb|CAA82665.1|   Hypothetical protein K03H1.10 [Caenorhabditis elegans]
          Length = 322

 Score = 61.4 bits (148), Expect = 2e-09
 Identities = 17/98 (17%), Positives = 32/98 (32%), Gaps = 18/98 (18%)

Query: 2   DVSGQETDWRST---AFRQKLVSQIEDAMRKAGVAHSKS---------SKDMESHVFLKA 49
           +V  +  +W        R  +V ++  A+                   ++ +E  VF  A
Sbjct: 161 NVPVRTKEWHRQVTNDLRNHIVGKLVKAIC-PAPEMMNDIRLKDLNAYARKVEKEVFETA 219

Query: 50  KTRDEYLSLVARLIIHFRDIHNKKS-----QASVSDPM 82
             R  Y  L+A  I   +    +K      Q +   P+
Sbjct: 220 IDRKNYYHLLAEKIYEIQKELQEKKNSRLNQGAAQSPL 257



>gi|24461867|gb|AAN62354.1|AF506028_23   CTV.22 [Poncirus trifoliata]
          Length = 1405

 Score = 42.5 bits (99), Expect = 0.001
 Identities = 21/113 (18%), Positives = 47/113 (41%), Gaps = 15/113 (13%)

Query: 9   DWRS---TAFRQKLVSQIEDAMRK----AGVAHSKSSKDM----ESHVFLKAKTRDEYLS 57
           DWR+      RQ++V++I D +++    +G       K +    E  ++  A ++ +YL 
Sbjct: 36  DWRTQLQPDSRQRIVNKIMDTLKRHLPFSGQDGLNELKKIAGRFEEKIYTAASSQSDYLR 95

Query: 58  LVARLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSL 110
            ++  ++        KSQ ++ + + +    +         +       GQSL
Sbjct: 96  KISLKMLSM----ESKSQNAMPNSLQSNNPGSSNRPPDPGSMQNQVHNQGQSL 144



>gi|24461860|gb|AAN62347.1|AF506028_14   CTV.20 [Poncirus trifoliata]
          Length = 3148

 Score = 40.2 bits (93), Expect = 0.006
 Identities = 16/83 (19%), Positives = 37/83 (44%), Gaps = 11/83 (13%)

Query: 8  TDWRST---AFRQKLVSQIEDAMRK----AGVAHSKSSKDM----ESHVFLKAKTRDEYL 56
          +DWR+      RQ++V++I D +++    +G       K +    E  +F  A ++ +YL
Sbjct: 15 SDWRNPLSHDSRQRIVNKIMDTLKRHLPFSGPEGLNELKRIADRFEEKIFTSATSQSDYL 74

Query: 57 SLVARLIIHFRDIHNKKSQASVS 79
            ++  ++         S ++  
Sbjct: 75 RKISLKMLSMESRSQNASGSNEP 97



>gi|17508323|ref|NP_493339.1|   KIX domain containing protein family member (80.3 kD)
           [Caenorhabditis elegans]
 gi|7505888|pir||T23651   hypothetical protein M01E5.6 - Caenorhabditis elegans
 gi|3878635|emb|CAB07643.1|   Hypothetical protein M01E5.6 [Caenorhabditis elegans]
 gi|3879438|emb|CAB03290.1|   Hypothetical protein M01E5.6 [Caenorhabditis elegans]
          Length = 702

 Score = 39.4 bits (91), Expect = 0.009
 Identities = 16/91 (17%), Positives = 33/91 (36%), Gaps = 12/91 (13%)

Query: 9   DWRSTAFRQKLVSQIEDAM-RK-------AGVAHSK---SSKDMESHVFLKAKTRDEYLS 57
           +W     R  +V ++  A   +        G    K   +++  E+ +   +  RDEY  
Sbjct: 601 EWIVEDIRNHMVGKLLKAFWPRIQNVEEMNGELFKKLIANARKCETEILEASNDRDEYYR 660

Query: 58  LVARLIIHF-RDIHNKKSQASVSDPMNALQS 87
           L+   +    +    K  +A+  +     QS
Sbjct: 661 LMQLTVDQILKKTLKKDQRATEHNHQQPTQS 691



>gi|28917231|gb|EAA26944.1|   hypothetical protein [Neurospora crassa]
          Length = 1430

 Score = 37.9 bits (87), Expect = 0.028
 Identities = 17/67 (25%), Positives = 26/67 (38%), Gaps = 6/67 (8%)

Query: 52  RDEYLSLVARLIIHFRDIHNKK-----SQASVSDPMNALQSLTGGPAAGA-AGIGMPPRG 105
           R+    L+ RL +H + +         S   +++ +NA   L G       A      R 
Sbjct: 536 REHAARLMQRLDLHRKAMLANSDTQAQSSGGIANLINASHGLIGNSPISPIAPQTPAVRV 595

Query: 106 PGQSLGG 112
           P  SLGG
Sbjct: 596 PIPSLGG 602



>gi|19570247|dbj|BAB86283.1|   kinesin-like protein NACK1 [Nicotiana tabacum]
          Length = 959

 Score = 35.6 bits (81), Expect = 0.13
 Identities = 22/89 (24%), Positives = 36/89 (40%), Gaps = 2/89 (2%)

Query: 8   TDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSK--DMESHVFLKAKTRDEYLSLVARLIIH 65
           +D +     QK V+++E  +R    A+ K  K   ME  +    + RD   S V  L   
Sbjct: 364 SDKQLVKHLQKEVARLEAELRTPDPANEKDWKIQQMEMEIEELKRQRDLAQSQVDELRRK 423

Query: 66  FRDIHNKKSQASVSDPMNALQSLTGGPAA 94
            ++    K   SVS  +    S +G  + 
Sbjct: 424 LQEEQGPKPSESVSPVVKKCLSFSGTLSP 452



>gi|17539958|ref|NP_501507.1|   Signal recognition particle (55.0 kD) [Caenorhabditis elegans]
 gi|7499565|pir||T21140   hypothetical protein F21D5.7 - Caenorhabditis elegans  (fragment)
 gi|25294403|pir||A88763   protein F21D5.7 [imported] - Caenorhabditis elegans
 gi|3876111|emb|CAA91040.1|   Hypothetical protein F21D5.7 [Caenorhabditis elegans]
 gi|3876124|emb|CAA92301.1|   Hypothetical protein F21D5.7 [Caenorhabditis elegans]
          Length = 496

 Score = 35.2 bits (80), Expect = 0.20
 Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 4/73 (5%)

Query: 56  LSLVARLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGS 115
            S V + I   + + N K+       MN  +              M PR     +GGMG 
Sbjct: 427 FSDVVKKIGSIKGLFNGKNGDINPKNMNPAKMAQLNQQMAKM---MDPRVLQ-QMGGMGG 482

Query: 116 LGAMGQPMSLSGQ 128
           L  M Q M+ +G+
Sbjct: 483 LQNMMQQMARAGK 495






  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF
    Posted date:  Jul 1, 2003  3:46 AM
  Number of letters in database: 469,658,079
  Number of sequences in database:  1,463,011
  
Lambda     K      H
   0.318    0.161    0.431 

Gapped
Lambda     K      H
   0.267   0.0493    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 134,051,974
Number of Sequences: 1463011
Number of extensions: 6223010
Number of successful extensions: 38766
Number of sequences better than  1.0: 157
Number of HSP's better than  1.0 without gapping: 73
Number of HSP's successfully gapped in prelim test: 90
Number of HSP's that attempted gapping in prelim test: 37760
Number of HSP's gapped (non-prelim): 657
length of query: 128
length of database: 469,658,079
effective HSP length: 104
effective length of query: 24
effective length of database: 317,504,935
effective search space: 7620118440
effective search space used: 7620118440
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)