BLASTP 2.2.6 [Apr-09-2003]

RID: 1063374235-25058-2563958.BLASTQ3

Query= P300_HUMAN gi|3024341|sp|Q09472|P300_HUMAN
E1A-associated protein p300
         (2414 letters)


Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF 
           1,522,899 sequences; 490,308,901 total letters

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557557|ref|NP_001420.1|  E1A binding protein p300; E1A-b...  1908   0.0  
gi|27663074|ref|XP_235502.1|  similar to E1A-associated prot...  1833   0.0  
gi|27666550|ref|XP_235770.1|  similar to E1A-associated prot...  1529   0.0  
gi|31753089|gb|AAH53889.1|  Unknown (protein for IMAGE:61513...  1404   0.0  
gi|4321116|gb|AAC51331.2|  CREB-binding protein [Homo sapiens]   1236   0.0  
gi|4758056|ref|NP_004371.1|  CREB binding protein [Homo sapi...  1234   0.0  
gi|19547885|gb|AAL87531.1|  CREB-binding protein [Mus muscul...  1225   0.0  
gi|631119|pir||S39162  transcription coactivator CREB-bindin...  1196   0.0  
gi|737920|prf||1923401A  protein CBP                             1186   0.0  
gi|1345703|sp|P45481|CBP_MOUSE  CREB-binding protein >gi|481...  1186   0.0  
gi|28486616|ref|XP_283295.1|  similar to E1A-associated prot...  1060   0.0  
gi|547239|gb|AAB31182.1|  p300=transcription coactivator {N-...  1031   0.0  
gi|31204369|ref|XP_311133.1|  ENSANGP00000004748 [Anopheles ...  1016   0.0  
gi|7511830|pir||T13828  CREB-binding protein homolog - fruit...   998   0.0  
gi|24640865|ref|NP_524642.2|  nejire CG15319-PB [Drosophila ...   991   0.0  
gi|21307831|gb|AAL54859.1|  CREB-binding protein [Aplysia ca...   943   0.0  
gi|2133462|pir||S60123  hypothetical protein R10E11.1 - Caen...   731   0.0  
gi|17552708|ref|NP_499161.1|  CBP/p300 homolog (cbp-1) [Caen...   729   0.0  
gi|17552710|ref|NP_499160.1|  CBP/p300 homolog (cbp-1) [Caen...   729   0.0  
gi|27881767|gb|AAH44677.1|  Similar to CREB binding protein ...   508   e-142
gi|19173764|ref|NP_596894.1|  E1A binding protein p300 [Ratt...   502   e-140
gi|1888540|gb|AAC51340.1|  CREB-binding protein [Homo sapiens]    438   e-121
gi|2996629|gb|AAC08447.1|  CBP [Homo sapiens]                     424   e-116
gi|28486618|ref|XP_128116.2|  similar to E1A-associated prot...   394   e-108
gi|3168627|gb|AAC17736.1|  CBP [Homo sapiens]                     340   2e-91
gi|27667568|ref|XP_213219.1|  similar to CREB-binding protei...   281   9e-74
gi|21105780|gb|AAM34788.1|AF512558_2  HAC5 [Arabidopsis thal...   258   1e-66
gi|15230656|ref|NP_187904.1|  CREB-binding protein -related ...   251   2e-64
gi|7487910|pir||T01055  hypothetical protein YUP8H12R.38 - A...   246   4e-63
gi|23200188|pdb|1JSP|B  Chain B, Nmr Structure Of Cbp Bromod...   244   2e-62
gi|18412221|ref|NP_565197.1|  p300/CBP acetyltransferase-rel...   244   2e-62
gi|18408717|ref|NP_564891.1|  hypothetical protein [Arabidop...   236   3e-60
gi|25518555|pir||E86302  hypothetical protein F17F16.8 [impo...   236   4e-60
gi|15219327|ref|NP_173115.1|  expressed protein [Arabidopsis...   234   1e-59
gi|5042442|gb|AAD38279.1|AC007789_5  putative CREB-binding p...   224   1e-56
gi|13486836|dbj|BAB40067.1|  putative CREB-binding protein [...   224   1e-56
gi|18405622|ref|NP_564706.1|  CREB-binding protein -related ...   220   2e-55
gi|6056385|gb|AAF02849.1|AC009894_20  Unknown protein [Arabi...   194   2e-47
gi|20664269|pdb|1L3E|B  Chain B, Nmr Structures Of The Hif-1...   191   1e-46
gi|8778322|gb|AAF79331.1|AC002304_24  F14J16.27 [Arabidopsis...   183   4e-44
gi|11514507|pdb|1F81|A  Chain A, Solution Structure Of The T...   177   2e-42
gi|20664319|pdb|1L8C|A  Chain A, Structural Basis For Hif-1a...   173   4e-41
gi|4139873|pdb|1KDX|A  Chain A, Kix Domain Of Mouse Cbp (Cre...   159   6e-37
gi|19173734|ref|NP_596872.1|  CREB binding protein; Creb bin...   143   3e-32
gi|17553334|ref|NP_499197.1|  CREB-binding protein like fami...   130   3e-28
gi|9368432|emb|CAB98139.1|  MOZ/CBP protein [Homo sapiens]        128   1e-27
gi|14794966|gb|AAK73519.1|  HAC4 [Arabidopsis thaliana]           123   5e-26
gi|21105785|gb|AAM34790.1|AF512560_2  HAC4 [Arabidopsis thal...   122   9e-26
gi|7494646|pir||T37269  hypothetical protein - Caenorhabditi...   112   9e-23
gi|482238|pir||S41033  hypothetical protein K03H1.10 - Caeno...   108   1e-21
gi|17554044|ref|NP_499201.1|  CREB-binding protein like fami...   108   1e-21
gi|9965307|gb|AAG10036.1|AF283834_1  transcription cofactor ...   105   2e-20
gi|23664002|gb|AAN39141.1|  CREB-binding protein [Rattus nor...   102   1e-19
gi|17552400|ref|NP_497145.1|  CREB-binding protein like fami...    89   1e-15
gi|17551090|ref|NP_510006.1|  CREB-binding protein like fami...    86   1e-14
gi|33146482|dbj|BAC79591.1|  putative RING3 protein [Oryza s...    82   1e-13
gi|29569106|gb|AAO84020.1|  global transcription factor grou...    80   7e-13
gi|19171509|emb|CAC84085.1|  hypothetical protein [Takifugu ...    78   2e-12
gi|7493489|pir||T40984  transcription factor bdf1 homolog SP...    77   3e-12
gi|17976800|emb|CAC83118.1|  WD repeat domain 11 protein [Ho...    77   6e-12
gi|12007334|gb|AAG45145.1|  IRS-1 PH domain binding protein ...    76   6e-12
gi|6016737|gb|AAF01563.1|AC009325_33  hypothetical protein [...    76   6e-12
gi|18395937|ref|NP_566151.1|  DNA-binding protein family [Ar...    76   7e-12
gi|16445438|ref|NP_387505.1|  WD repeat domain 9 isoform B; ...    76   7e-12
gi|23831562|sp|Q9NSI6|WDR9_HUMAN  WD-repeat protein 9 >gi|20...    76   7e-12
gi|7717364|emb|CAB90452.1|  homolog to cAMP response element...    76   7e-12
gi|14970564|emb|CAC44372.1|  WDR9 protein, form B [Homo sapi...    76   7e-12
gi|16445436|ref|NP_061836.2|  WD repeat domain 9 isoform A; ...    76   8e-12
gi|33417197|gb|AAH55508.1|  Unknown (protein for IMAGE:38191...    76   9e-12
gi|14970562|emb|CAC44371.1|  WDR9 protein, form A [Homo sapi...    76   9e-12
gi|12007336|gb|AAG45146.1|  IRS-1 PH domain binding protein ...    76   1e-11
gi|1502355|emb|CAA67614.1|  GCN5 [Saccharomyces cerevisiae]        75   1e-11
gi|13699186|dbj|BAB41205.1|  kinase-like protein [Oryza sativa]    75   1e-11
gi|27720883|ref|XP_236438.1|  similar to WD repeat domain 11...    75   1e-11
gi|7020972|dbj|BAA91336.1|  unnamed protein product [Homo sa...    75   2e-11
gi|20149648|ref|NP_060404.2|  pleckstrin homology domain int...    75   2e-11
gi|6321691|ref|NP_011768.1|  functions in the Ada and SAGA (...    75   2e-11
gi|17976802|emb|CAC83119.1|  WD repeat domain 11 protein [Mu...    75   2e-11
gi|15242727|ref|NP_201138.1|  DNA-binding protein family [Ar...    74   3e-11
gi|19114532|ref|NP_593620.1|  protein with 2 bromodomains, p...    74   3e-11
gi|24659254|ref|NP_726307.1|  CG30417-PA [Drosophila melanog...    74   3e-11
gi|19173489|ref|NP_597292.1|  GENERAL TRANSCRIPTION FACTOR [...    74   3e-11
gi|6320132|ref|NP_010213.1|  bromodomain protein, homolog of...    74   4e-11
gi|22761009|dbj|BAC11417.1|  unnamed protein product [Homo s...    74   4e-11
gi|11513447|pdb|1E6I|A  Chain A, Bromodomain From Gcn5 Compl...    74   4e-11
gi|33416865|gb|AAH55543.1|  Unknown (protein for IMAGE:59138...    73   8e-11
gi|24649631|ref|NP_732982.1|  CG31132-PA [Drosophila melanog...    72   1e-10
gi|15231174|ref|NP_190796.1|  hypothetical protein [Arabidop...    72   1e-10
gi|1588281|prf||2208296A  RING3 protein                            72   1e-10
gi|18157527|dbj|BAB83842.1|  BRD2~partially supported by GEN...    72   1e-10
gi|24210305|emb|CAD54663.1|  SI:dZ12F11.5 (bromodomain-conta...    72   1e-10
gi|16905089|ref|NP_473395.1|  female sterile homeotic-relate...    72   1e-10
gi|7485801|pir||T00472  probable RING3 protein [imported] - ...    72   1e-10
gi|32420965|ref|XP_330926.1|  hypothetical protein [Neurospo...    72   1e-10
gi|28278510|gb|AAH45866.1|  Similar to bromodomain containin...    72   1e-10
gi|31241187|ref|XP_321024.1|  ENSANGP00000011207 [Anopheles ...    72   1e-10
gi|27469649|gb|AAH38844.1|  Unknown (protein for IMAGE:57426...    72   2e-10
gi|30686240|ref|NP_181036.2|  RING3 protein -related [Arabid...    72   2e-10
gi|14970593|emb|CAC44374.1|  WDR protein, form B [Mus musculus]    72   2e-10
gi|26332152|dbj|BAC29806.1|  unnamed protein product [Mus mu...    72   2e-10

Alignments

>gi|4557557|ref|NP_001420.1| E1A binding protein p300; E1A-binding protein, 300kD [Homo sapiens]
 gi|3024341|sp|Q09472|P300_HUMAN E1A-associated protein p300
 gi|627657|pir||A54277 transcription adaptor protein p300 - human
 gi|495301|gb|AAA18639.1| p300 protein
          Length = 2414

 Score = 1908 bits (4942), Expect = 0.0
 Identities = 1071/1446 (74%), Positives = 1071/1446 (74%)

Query: 945  VSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVED 1004
            VSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVED
Sbjct: 945  VSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVED 1004

Query: 1005 CKMXXXXXXXXXXXXXXXIKEEEDXXXXXXXXXXXXXGQSKKKIFKPEELRQALMPTLEA 1064
            CKM               IKEEED             GQSKKKIFKPEELRQALMPTLEA
Sbjct: 1005 CKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEA 1064

Query: 1065 LYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLM 1124
            LYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLM
Sbjct: 1065 LYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLM 1124

Query: 1125 FNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCT 1184
            FNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCT
Sbjct: 1125 FNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCT 1184

Query: 1185 IPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELF 1244
            IPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELF
Sbjct: 1185 IPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELF 1244

Query: 1245 VECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLEN 1304
            VECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLEN
Sbjct: 1245 VECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLEN 1304

Query: 1305 RVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFE 1364
            RVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFE
Sbjct: 1305 RVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFE 1364

Query: 1365 EIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEY 1424
            EIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEY
Sbjct: 1365 EIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEY 1424

Query: 1425 VKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYK 1484
            VKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYK
Sbjct: 1425 VKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYK 1484

Query: 1485 DIFKQATEDRLTSAKELPYFEGDFWPNVXXXXXXXXXXXXXXXXXXXXXXXXSTDVTKGD 1544
            DIFKQATEDRLTSAKELPYFEGDFWPNV                        STDVTKGD
Sbjct: 1485 DIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESTDVTKGD 1544

Query: 1545 XXXXXXXXXXXXXXXXXXLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGP 1604
                              LSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGP
Sbjct: 1545 SKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGP 1604

Query: 1605 AANSXXXXXXXXXXXXXXXMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQD 1664
            AANS               MDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQD
Sbjct: 1605 AANSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQD 1664

Query: 1665 RFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAAT 1724
            RFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAAT
Sbjct: 1665 RFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAAT 1724

Query: 1725 QSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQ 1784
            QSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQ
Sbjct: 1725 QSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQ 1784

Query: 1785 LIALCCYHAKHCQENKCPVPFCLNIKXXXXXXXXXXXXXXXXXXXXXXXXXXXTGVVGQQ 1844
            LIALCCYHAKHCQENKCPVPFCLNIK                           TGVVGQQ
Sbjct: 1785 LIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQ 1844

Query: 1845 QGLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYLPRTQAAGPVSQGKXXXX 1904
            QGL                                      YLPRTQAAGPVSQGK    
Sbjct: 1845 QGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQ 1904

Query: 1905 XXXXXXXXXXXXXXXXXXXXXXEMAMQIQRAAETQRQMAHVQIFQRPIQHQXXXXXXXXX 1964
                                  EMAMQIQRAAETQRQMAHVQIFQRPIQHQ         
Sbjct: 1905 VTPPTPPQTAQPPLPGPPPTAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAP 1964

Query: 1965 XXXXXXXXTRGPSGHLEPGMGPTGMXXXXXXXXXXXXXXXXXXXXMPRPAMMSVAQHGQP 2024
                    TRGPSGHLEPGMGPTGM                    MPRPAMMSVAQHGQP
Sbjct: 1965 MGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQP 2024

Query: 2025 LNMAPQPGLGQVGISPLKPGTVSQQALQNXXXXXXXXXXXXXXXXXXXXXHANPQLLAAF 2084
            LNMAPQPGLGQVGISPLKPGTVSQQALQN                     HANPQLLAAF
Sbjct: 2025 LNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAF 2084

Query: 2085 IKQRAAKYANSNXXXXXXXXXXXXXXXXXXXXXXXXXXXVHSNPAMQNMNPMQAGVQRAG 2144
            IKQRAAKYANSN                           VHSNPAMQNMNPMQAGVQRAG
Sbjct: 2085 IKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAG 2144

Query: 2145 XXXXXXXXXXXXXMGGMSPQAQQMNMNHNTMPSQFRDILRRXXXXXXXXXXGAGPGIGPG 2204
                         MGGMSPQAQQMNMNHNTMPSQFRDILRR          GAGPGIGPG
Sbjct: 2145 LPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPG 2204

Query: 2205 MANHNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLPQALGAEAGASXXXXXXXX 2264
            MANHN                                   LPQALGAEAGAS        
Sbjct: 2205 MANHNQFQQPQGVGYPPQPQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRL 2264

Query: 2265 XXXXMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNXXXXXXXXXXXXXXXXXXX 2324
                MGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSN                   
Sbjct: 2265 LQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPH 2324

Query: 2325 XXXXXXXXXXXXXXXXXXXXXXXXXGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMAN 2384
                                     GLVAAQANPMEQGHFASPDQNSMLSQLASNPGMAN
Sbjct: 2325 SSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMAN 2384

Query: 2385 LHGASA 2390
            LHGASA
Sbjct: 2385 LHGASA 2390




 Score = 1385 bits (3584), Expect = 0.0
 Identities = 765/830 (92%), Positives = 765/830 (92%)

Query: 1   MAENVVEPGPPSAKRPKXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
           MAENVVEPGPPSAKRPK           DGTDFGSLFDLEHDLPDELINSTELGLTNGGD
Sbjct: 1   MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60

Query: 61  INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS 120
           INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS
Sbjct: 61  INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS 120

Query: 121 MVKSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGTNAGMNPGMLAA 180
           MVKSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGTNAGMNPGMLAA
Sbjct: 121 MVKSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGTNAGMNPGMLAA 180

Query: 181 GNGQGIMPNQVMNGSIGAGRGRQDMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQ 240
           GNGQGIMPNQVMNGSIGAGRGRQDMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQ
Sbjct: 181 GNGQGIMPNQVMNGSIGAGRGRQDMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQ 240

Query: 241 PLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVXXXXXX 300
           PLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAV      
Sbjct: 241 PLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMP 300

Query: 301 XXXXXXXXXXXXXGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGE 360
                        GLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGE
Sbjct: 301 NMGQQPAPQVQQPGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGE 360

Query: 361 VRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA 420
           VRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA
Sbjct: 361 VRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA 420

Query: 421 GDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQM 480
           GDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQM
Sbjct: 421 GDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQM 480

Query: 481 XXXXXXXXXXXXXXXXXXXXXGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQ 540
                                GMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQ
Sbjct: 481 PTQPQVQAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQ 540

Query: 541 NPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAAL 600
           NPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAAL
Sbjct: 541 NPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAAL 600

Query: 601 KDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPN 660
           KDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPN
Sbjct: 601 KDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPN 660

Query: 661 AAGMVPVSXXXXXXXXXXXXXXTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSM 720
           AAGMVPVS              TSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSM
Sbjct: 661 AAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSM 720

Query: 721 AQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNI 780
           AQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNI
Sbjct: 721 AQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNI 780

Query: 781 PLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN 830
           PLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN
Sbjct: 781 PLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN 830



>gi|27663074|ref|XP_235502.1| similar to E1A-associated protein p300 [Rattus norvegicus]
          Length = 2156

 Score = 1833 bits (4749), Expect = 0.0
 Identities = 1040/1495 (69%), Positives = 1054/1495 (70%), Gaps = 56/1495 (3%)

Query: 945  VSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVED 1004
            VS+EGQVSNPPSTSSTEVNSQ I EKQPSQEVKME KM+VDQPEPAD QP+D  E+K ED
Sbjct: 584  VSVEGQVSNPPSTSSTEVNSQTIPEKQPSQEVKMEVKMDVDQPEPADAQPDDTKEAKAED 643

Query: 1005 CKMXXXXXXXXXXXXXXXIKEEEDXXXXXXXXXXXXXGQSKKKIFKPEELRQALMPTLEA 1064
             K+               +KEEED             GQSKKKIFKPEELRQALMPTLEA
Sbjct: 644  GKVEPTETEERGPELKTEVKEEEDQPSTSAAQSSPAPGQSKKKIFKPEELRQALMPTLEA 703

Query: 1065 LYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLM 1124
            LYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQY+DDIWLM
Sbjct: 704  LYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYIDDIWLM 763

Query: 1125 FNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRK------------LEFSP 1172
            FNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRK            LEFSP
Sbjct: 764  FNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKVFALLNKYFLLQLEFSP 823

Query: 1173 QTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFS 1232
            QTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFS
Sbjct: 824  QTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFS 883

Query: 1233 KRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKR 1292
            KRKNDTLDPELFVECTECGRKMHQICVLHHE+IWP+GFVCDGCLKK+ARTRKENKFSAKR
Sbjct: 884  KRKNDTLDPELFVECTECGRKMHQICVLHHEVIWPSGFVCDGCLKKTARTRKENKFSAKR 943

Query: 1293 LPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKAR---------- 1342
            LPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKAR          
Sbjct: 944  LPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARCLVISHSLLT 1003

Query: 1343 ----FVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYL 1398
                FVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYL
Sbjct: 1004 DLQLFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYL 1063

Query: 1399 DSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIP 1458
            DSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIP
Sbjct: 1064 DSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIP 1123

Query: 1459 KPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVXXXXXX 1518
            KPKRLQEWYKKMLDKAVSERIVHDYKDI KQATEDRLTSAKELPYFEGDFWPNV      
Sbjct: 1124 KPKRLQEWYKKMLDKAVSERIVHDYKDILKQATEDRLTSAKELPYFEGDFWPNVLEESIK 1183

Query: 1519 XXXXXXXXXXXXXXXXXXSTDVTKGDXXXXXXXXXXXXXXXXXXLSRGNKKKPGMPNVSN 1578
                              STDVTKGD                  LSRGNKKKPG+PNVSN
Sbjct: 1184 ELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGVPNVSN 1243

Query: 1579 DLSQKLYATMEKHKE---------------VFFVIRLIAGPAANSXXXXXXXXXXXXXXX 1623
            DLSQKLYATMEKHKE               VFFVIRLIA PA NS               
Sbjct: 1244 DLSQKLYATMEKHKEWHYSSRVTVSLVCWQVFFVIRLIACPAPNSLPPIVDPDPLIPCDL 1303

Query: 1624 MDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHC 1683
            MDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHC
Sbjct: 1304 MDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHC 1363

Query: 1684 TVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLV 1743
            TVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLV
Sbjct: 1364 TVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLV 1423

Query: 1744 HACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPV 1803
            HACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPV
Sbjct: 1424 HACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPV 1483

Query: 1804 PFCLNIKXXXXXXXXXXXXXXXXXXXXXXXXXXXTGVVGQQQGL--XXXXXXXXXXXXXX 1861
            PFCLNIK                           TGV GQQQGL                
Sbjct: 1484 PFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVAGQQQGLPSPTPATPTTPTGQQP 1543

Query: 1862 XXXXXXXXXXXXXXXXXXXXXXXXYLPRTQAAGPVSQGKXXXXXXXXXXXXXXXXXXXXX 1921
                                    YLPRTQ AGPVSQGK                     
Sbjct: 1544 ATPQTPQPQPTSQPQPTPPNNMTPYLPRTQTAGPVSQGKAAGQVTPPTPPQTAQPPLPGP 1603

Query: 1922 XXXXXEMAMQIQRAAETQRQMAHVQIFQRPIQHQXXXXXXXXXXXXXXXXXTRGPSGHLE 1981
                 EMAMQIQRAAETQRQMAHVQIFQRPIQHQ                  RGP GHL+
Sbjct: 1604 PPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ---MAPMAPMGMNPPPMARGPGGHLD 1660

Query: 1982 PGMGPTGMXXXXXXXXXXXXXXXXXXXXMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPL 2041
            PGMGP GM                    MPRPAMMSVAQHGQPLNMAPQPGLGQVG+SPL
Sbjct: 1661 PGMGPAGMQQQPPWAQGGMPQPQQMQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGVSPL 1720

Query: 2042 KPGTVSQQALQNXXXXXXXXXXXXXXXXXXXXXHANPQLLAAFIKQRAAKYANSNXXXXX 2101
            KPGTVSQQALQN                     HANPQLLAAFIKQRAAKYANSN     
Sbjct: 1721 KPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPLP 1780

Query: 2102 XXXXXXXXXXXXXXXXXXXXXXVHSNPAMQNMNPMQAGVQRAGXXXXXXXXXXXXXMGGM 2161
                                  VHSNPA+QNMNPMQAGVQRAG             MGGM
Sbjct: 1781 GQPGMPQGQPGLQPPTMPGQQGVHSNPALQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGM 1840

Query: 2162 SPQAQQMNMNHNTMPSQFRDILRRXXXXXXXXXXGAGPGIGPGMANHN-----XXXXXXX 2216
            SPQAQQMNMNHNTMPSQFRDILRR          GAGPGIGPGMANHN            
Sbjct: 1841 SPQAQQMNMNHNTMPSQFRDILRR----QMMQQQGAGPGIGPGMANHNQFQQPQGIGYPP 1896

Query: 2217 XXXXXXXXXXXXXXXXXXXXXXXXXXXXLPQALGAEAGASXXXXXXXXXXXXMGSPVQPN 2276
                                        LPQALGAEAGAS            MGSP QPN
Sbjct: 1897 QQQQQQQQQRMQHHMQQMQQGNMGQMGQLPQALGAEAGASLQAYQQRLLQQQMGSPAQPN 1956

Query: 2277 PMSPQQHMLPNQAQSPHLQGQQIPNSLSNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2336
            PMSPQQHMLPNQAQSPHLQGQQIPNSLSN                               
Sbjct: 1957 PMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPS 2016

Query: 2337 XXXXXXXXXXXXXGLVAAQ-ANPMEQGHFASPDQNSMLSQLASNPGMANLHGASA 2390
                         GLVAAQ ANPMEQGHFASPDQNSMLSQLASNPGMANLHGASA
Sbjct: 2017 PHHVSPQTSSPHPGLVAAQAANPMEQGHFASPDQNSMLSQLASNPGMANLHGASA 2071




 Score =  714 bits (1843), Expect = 0.0
 Identities = 388/472 (82%), Positives = 403/472 (85%), Gaps = 14/472 (2%)

Query: 372 MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILT 431
           MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQ ILT
Sbjct: 1   MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQSILT 60

Query: 432 GAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMXXXXXXXXXXX 491
           GAPVGLGNPSSLGVGQQS P+LSTVSQIDPSSIERAYAALGLPYQVNQ+           
Sbjct: 61  GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQIPPQPPVQAKNQ 120

Query: 492 XXXXXXXXXXGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQNPMMSENASVP 551
                     GMR M+NMSASPMGVNGGVGVQTP+LLSDSMLHS INSQNPMM+ENASV 
Sbjct: 121 QSQPSGQSPQGMRSMNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMMNENASVA 180

Query: 552 SLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY 611
           SLGP+PTAAQPS+TGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY
Sbjct: 181 SLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY 240

Query: 612 ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSXXX 671
           ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP+A GMVPV    
Sbjct: 241 ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPSAPGMVPVPMNT 300

Query: 672 XXXXXXXXXXXTS-------------NGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQM 718
                      T+             +GPLPDPSMIRGSVPNQMMPR+TPQ GLNQFGQM
Sbjct: 301 APNMGQQPTGMTTKTKGYLTISVSTPDGPLPDPSMIRGSVPNQMMPRMTPQPGLNQFGQM 360

Query: 719 SMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVT 778
           ++ QPPI PRQ  PLQHHGQLAQ G+LNPPMGYGPRMQQ S Q QFL QTQFPSQGMNVT
Sbjct: 361 NIPQPPIGPRQPSPLQHHGQLAQSGSLNPPMGYGPRMQQTSGQNQFLSQTQFPSQGMNVT 420

Query: 779 NIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN 830
           N+PLAPSS QAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCP LPQ A HQN
Sbjct: 421 NMPLAPSSSQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPTLPQQA-HQN 471



>gi|27666550|ref|XP_235770.1| similar to E1A-associated protein p300 [Rattus norvegicus]
          Length = 1605

 Score = 1530 bits (3960), Expect = 0.0
 Identities = 836/1181 (70%), Positives = 849/1181 (71%), Gaps = 85/1181 (7%)

Query: 945  VSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVED 1004
            VS+EGQVSNPPSTSSTEVNSQ I EKQPSQEVKME KM+VDQPEPAD QP+D  E+K ED
Sbjct: 442  VSVEGQVSNPPSTSSTEVNSQTIPEKQPSQEVKMEVKMDVDQPEPADAQPDDTKEAKAED 501

Query: 1005 CKMXXXXXXXXXXXXXXXIKEEEDXXXXXXXXXXXXXGQSKKKIFKPEELRQALMPTLEA 1064
             K+               +KEEED             GQSKKKIFKPEELRQALMPTLEA
Sbjct: 502  GKVEPTETEERGPELKTEVKEEEDQPSTSAAQSSPAPGQSKKKIFKPEELRQALMPTLEA 561

Query: 1065 LYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLM 1124
            LYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQY+DDIWLM
Sbjct: 562  LYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYIDDIWLM 621

Query: 1125 FNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRK------------LEFSP 1172
            FNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRK            LEFSP
Sbjct: 622  FNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKVFALLNKYFLLQLEFSP 681

Query: 1173 QTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFS 1232
            QTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFS
Sbjct: 682  QTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFS 741

Query: 1233 KRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKR 1292
            KRKNDTLDPELFVECTECGRKMHQICVLHHE+IWP+GFVCDGCLKK+ARTRKENKFSAKR
Sbjct: 742  KRKNDTLDPELFVECTECGRKMHQICVLHHEVIWPSGFVCDGCLKKTARTRKENKFSAKR 801

Query: 1293 LPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAES 1352
            LPSTRLGTFLENR                                               
Sbjct: 802  LPSTRLGTFLENR----------------------------------------------- 814

Query: 1353 FPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTA 1412
                  ALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTA
Sbjct: 815  ------ALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTA 868

Query: 1413 VYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLD 1472
            VYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLD
Sbjct: 869  VYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLD 928

Query: 1473 KAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVXXXXXXXXXXXXXXXXXXXX 1532
            KAVSERIVHDYKDI KQATEDRLTSAKELPYFEGDFWPNV                    
Sbjct: 929  KAVSERIVHDYKDILKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREEN 988

Query: 1533 XXXXSTDVTKGDXXXXXXXXXXXXXXXXXXLSRGNKKKPGMPNVSNDLSQKLYATMEKHK 1592
                STDVTKGD                  LSRGNKKKPG+PNVSNDLSQKLYATMEKHK
Sbjct: 989  TSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGVPNVSNDLSQKLYATMEKHK 1048

Query: 1593 E---------------VFFVIRLIAGPAANSXXXXXXXXXXXXXXXMDGRDAFLTLARDK 1637
            E               VFFVIRLIA PA NS               MDGRDAFLTLARDK
Sbjct: 1049 EWHYSSRVTVSLVCWQVFFVIRLIACPAPNSLPPIVDPDPLIPCDLMDGRDAFLTLARDK 1108

Query: 1638 HLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYN 1697
            HLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYN
Sbjct: 1109 HLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYN 1168

Query: 1698 TKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPS 1757
            TKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPS
Sbjct: 1169 TKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPS 1228

Query: 1758 CQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKXXXXXXX 1817
            CQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIK       
Sbjct: 1229 CQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQ 1288

Query: 1818 XXXXXXXXXXXXXXXXXXXXTGVVGQQQGL--XXXXXXXXXXXXXXXXXXXXXXXXXXXX 1875
                                TGV GQQQGL                              
Sbjct: 1289 LQHRLQQAQMLRRRMASMQRTGVAGQQQGLPSPTPATPTTPTGQQPATPQTPQPQPTSQP 1348

Query: 1876 XXXXXXXXXXYLPRTQAAGPVSQGKXXXXXXXXXXXXXXXXXXXXXXXXXXEMAMQIQRA 1935
                      YLPRTQ AGPVSQGK                          EMAMQIQRA
Sbjct: 1349 QPTPPNNMTPYLPRTQTAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRA 1408

Query: 1936 AETQRQMAHVQIFQRPIQHQXXXXXXXXXXXXXXXXXTRGPSGHLEPGMGPTGMXXXXXX 1995
            AETQRQMAHVQIFQRPIQHQ                  RGP GHL+PGMGP GM      
Sbjct: 1409 AETQRQMAHVQIFQRPIQHQ---MAPMAPMGMNPPPMARGPGGHLDPGMGPAGMQQQPPW 1465

Query: 1996 XXXXXXXXXXXXXXMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNXX 2055
                          MPRPAMMSVAQHGQPLNMAPQPGLGQVG+SPLKPGTVSQQALQN  
Sbjct: 1466 AQGGMPQPQQMQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGVSPLKPGTVSQQALQNLL 1525

Query: 2056 XXXXXXXXXXXXXXXXXXXHANPQLLAAFIKQRAAKYANSN 2096
                               HANPQLLAAFIKQRAAKYANSN
Sbjct: 1526 RTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSN 1566




 Score =  535 bits (1379), Expect = e-150
 Identities = 291/371 (78%), Positives = 304/371 (81%), Gaps = 17/371 (4%)

Query: 372 MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILT 431
           MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQ ILT
Sbjct: 1   MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQSILT 60

Query: 432 GAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMXXXXXXXXXXX 491
           GAPVGLGNPSSLGVGQQS P+LSTVSQIDPSSIERAYAALGLPYQVNQ+           
Sbjct: 61  GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQIPPQPPVQAKNQ 120

Query: 492 XXXXXXXXXXGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQNPMMSENASVP 551
                     GMR M+NMSASPMGVNGGVGVQTP+LLSDSMLHS INSQNPMM+ENASV 
Sbjct: 121 QSQPSGQSPQGMRSMNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMMNENASVA 180

Query: 552 SLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY 611
           SLGP+PTAAQPS+TGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY
Sbjct: 181 SLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY 240

Query: 612 ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSXXX 671
           ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP+A GMVPV    
Sbjct: 241 ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPSAPGMVPVPMNT 300

Query: 672 XXXXXXXXXXXTS-------------NGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQM 718
                      T+             +GPLPDPSMIRGSVPNQMMPR+TPQ G     Q 
Sbjct: 301 APNMGQQPTGMTTKTKGYLTISVSTPDGPLPDPSMIRGSVPNQMMPRMTPQPG----SQG 356

Query: 719 SMAQPPIVPRQ 729
           S    P +P+Q
Sbjct: 357 SHIHCPTLPQQ 367




 Score = 42.7 bits (99), Expect = 0.093
 Identities = 40/119 (33%), Positives = 53/119 (44%), Gaps = 27/119 (22%)

Query: 722 QPPIVPRQTPPLQHHGQL-AQPGALNPPMGYGPRM-QQPSNQGQFLPQTQFPSQGMNVTN 779
           Q  +  ++   LQ    L + PG +  PM   P M QQP+              GM    
Sbjct: 270 QKELEEKRRTRLQKQNMLPSAPGMVPVPMNTAPNMGQQPT--------------GMTTKT 315

Query: 780 ---IPLAPSSGQAPVSQAQMSSSSCPVNSPIMP-----PGSQGSHIHCPQLPQPALHQN 830
              + ++ S+   P+    M   S P  + +MP     PGSQGSHIHCP LPQ A HQN
Sbjct: 316 KGYLTISVSTPDGPLPDPSMIRGSVP--NQMMPRMTPQPGSQGSHIHCPTLPQQA-HQN 371



>gi|31753089|gb|AAH53889.1| Unknown (protein for IMAGE:6151364) [Homo sapiens]
          Length = 1553

 Score = 1404 bits (3633), Expect = 0.0
 Identities = 763/830 (91%), Positives = 764/830 (92%)

Query: 1   MAENVVEPGPPSAKRPKXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
           MAENVVEPGPPSAKRPK           DGTDFGSLFDLEHDLPDELINSTELGLTNGGD
Sbjct: 1   MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60

Query: 61  INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS 120
           INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS
Sbjct: 61  INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS 120

Query: 121 MVKSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGTNAGMNPGMLAA 180
           MVKSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTG NAGMNPGMLAA
Sbjct: 121 MVKSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGMNAGMNPGMLAA 180

Query: 181 GNGQGIMPNQVMNGSIGAGRGRQDMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQ 240
           GNGQGIMPNQVMNGSIGAGRGRQ+MQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQ
Sbjct: 181 GNGQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQ 240

Query: 241 PLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVXXXXXX 300
           PLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAV      
Sbjct: 241 PLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMP 300

Query: 301 XXXXXXXXXXXXXGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGE 360
                        GLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGE
Sbjct: 301 NMGQQPAPQVQQPGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGE 360

Query: 361 VRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA 420
           VRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA
Sbjct: 361 VRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA 420

Query: 421 GDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQM 480
           GDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQM
Sbjct: 421 GDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQM 480

Query: 481 XXXXXXXXXXXXXXXXXXXXXGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQ 540
                                GMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQ
Sbjct: 481 PTQPQVQAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQ 540

Query: 541 NPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAAL 600
           NPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAAL
Sbjct: 541 NPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAAL 600

Query: 601 KDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPN 660
           KDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPN
Sbjct: 601 KDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPN 660

Query: 661 AAGMVPVSXXXXXXXXXXXXXXTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSM 720
           AAGMVPVS              TSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSM
Sbjct: 661 AAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSM 720

Query: 721 AQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNI 780
           AQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNI
Sbjct: 721 AQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNI 780

Query: 781 PLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN 830
           PLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN
Sbjct: 781 PLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN 830




 Score = 1038 bits (2685), Expect = 0.0
 Identities = 548/600 (91%), Positives = 548/600 (91%)

Query: 945  VSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVED 1004
            VSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVED
Sbjct: 945  VSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVED 1004

Query: 1005 CKMXXXXXXXXXXXXXXXIKEEEDXXXXXXXXXXXXXGQSKKKIFKPEELRQALMPTLEA 1064
            CKM               IKEEED             GQSKKKIFKPEELRQALMPTLEA
Sbjct: 1005 CKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEA 1064

Query: 1065 LYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLM 1124
            LYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLM
Sbjct: 1065 LYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLM 1124

Query: 1125 FNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCT 1184
            FNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCT
Sbjct: 1125 FNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCT 1184

Query: 1185 IPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELF 1244
            IPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELF
Sbjct: 1185 IPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELF 1244

Query: 1245 VECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLEN 1304
            VECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLEN
Sbjct: 1245 VECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLEN 1304

Query: 1305 RVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFE 1364
            RVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFE
Sbjct: 1305 RVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFE 1364

Query: 1365 EIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEY 1424
            EIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEY
Sbjct: 1365 EIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEY 1424

Query: 1425 VKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYK 1484
            VKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYK
Sbjct: 1425 VKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYK 1484

Query: 1485 DIFKQATEDRLTSAKELPYFEGDFWPNVXXXXXXXXXXXXXXXXXXXXXXXXSTDVTKGD 1544
            DIFKQATEDRLTSAKELPYFEGDFWPNV                        STDVTKGD
Sbjct: 1485 DIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESTDVTKGD 1544



>gi|4321116|gb|AAC51331.2| CREB-binding protein [Homo sapiens]
          Length = 2442

 Score = 1236 bits (3197), Expect = 0.0
 Identities = 655/881 (74%), Positives = 708/881 (80%), Gaps = 16/881 (1%)

Query: 946  SIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDC 1005
            SI+ +V  P S +S E NSQ      P  E+K E + E  +P+P +++ E  SE   ED 
Sbjct: 967  SIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDL 1026

Query: 1006 KMXXXXXXXXXXXXXXXIKEEED---------------XXXXXXXXXXXXXGQSKKKIFK 1050
            +                   E D                             Q +KKIFK
Sbjct: 1027 QGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFK 1086

Query: 1051 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQ 1110
            PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK+PMDLSTIKRKLDTGQ
Sbjct: 1087 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQ 1146

Query: 1111 YQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEF 1170
            YQEPWQYVDD+WLMFNNAWLYNRKTSRVYK+CSKL+EVFEQEIDPVMQSLGYCCGRK EF
Sbjct: 1147 YQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEF 1206

Query: 1171 SPQTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQ 1230
            SPQTLCCYGKQLCTIPRDA YYSYQNRYHFCEKCF EIQGE+V+LGDDPSQPQTTI+K+Q
Sbjct: 1207 SPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQ 1266

Query: 1231 FSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSA 1290
            F K+KNDTLDPE FV+C ECGRKMHQICVLH++IIWP+GFVCD CLKK+ R RKENKFSA
Sbjct: 1267 FEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSA 1326

Query: 1291 KRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMA 1350
            KRL +TRLG  LE+RVN FLRRQNHPE+GEV VRVV +SDKTVEVKPGMK+RFVDSGEM+
Sbjct: 1327 KRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMS 1386

Query: 1351 ESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLR 1410
            ESFPYRTKALFAFEEIDGVD+CFFGMHVQEYGSDCPPPN RRVYISYLDS+HFFRP+CLR
Sbjct: 1387 ESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLR 1446

Query: 1411 TAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM 1470
            TAVYHEILIGYLEYVKKLGY TGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM
Sbjct: 1447 TAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM 1506

Query: 1471 LDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNV-XXXXXXXXXXXXXXXXX 1529
            LDKA +ERI+HDYKDIFKQATEDRLTSAKELPYFEGDFWPNV                  
Sbjct: 1507 LDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKE 1566

Query: 1530 XXXXXXXSTDVTKGDXXXXXXXXXXXXXXXXXXLSRGNKKKPGMPNVSNDLSQKLYATME 1589
                   +T+ ++GD                  +SR NKKKP MPNVSNDLSQKLYATME
Sbjct: 1567 ESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATME 1626

Query: 1590 KHKEVFFVIRLIAGPAANSXXXXXXXXXXXXXXXMDGRDAFLTLARDKHLEFSSLRRAQW 1649
            KHKEVFFVI L AGP  N+               MDGRDAFLTLARDKH EFSSLRR++W
Sbjct: 1627 KHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKW 1686

Query: 1650 STMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLG 1709
            ST+CMLVELHTQ QDRFVYTCNECKHHVETRWHCTVCEDYDLCI CYNTK+H HKM K G
Sbjct: 1687 STLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWG 1746

Query: 1710 LGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK 1769
            LGLDDE ++Q    ++SP +SRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK
Sbjct: 1747 LGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK 1806

Query: 1770 GCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIK 1810
            GCKRKTNGGCP+CKQLIALCCYHAKHCQENKCPVPFCLNIK
Sbjct: 1807 GCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIK 1847




 Score =  560 bits (1444), Expect = e-157
 Identities = 409/891 (45%), Positives = 514/891 (57%), Gaps = 100/891 (11%)

Query: 1   MAENVVEPGPPSAKRPKXXXXXXXXXXXDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG 59
           MAEN+++ GPP+ KR K           D TDFGSLFDLE+DLPDELI N  ELGL N G
Sbjct: 1   MAENLLD-GPPNPKRAK--LSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSG 57

Query: 60  DINQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGG--------PGQVMASQAQQS 111
           +         +V DAASKHKQLSELLR GS  ++N G+G          G    +Q Q +
Sbjct: 58  N---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN 108

Query: 112 SPGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQ 160
           S  +  +++M KSP++Q   ++P++      TSGP    +Q+         G+  S    
Sbjct: 109 SANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT 168

Query: 161 PAMGMNTGTNAGMN---PGMLAAGNGQGIMPN------QVMNGSI--GAGRGRQDMQYPN 209
              G     NA  N   PG+L + +G  ++        QVMNGS+          M YP 
Sbjct: 169 SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPT 228

Query: 210 PGM-GSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQI 265
           P M G++ ++L E L Q SPQM G  GL   Q     KMG+  N +P+G P++Q  GQ +
Sbjct: 229 PAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPM 288

Query: 266 GASGLGLQIQTKTVLSNNLSPFAMDKKAVXXXXXXXXXXXXXXXXXXXGLVTPVAQGMGS 325
           GA+G+  Q+ +K  + N+L  F  D K                     G+V   A   G 
Sbjct: 289 GATGVNPQLASKQSMVNSLPTFPTDIKNT----SVTNVPNMSQMQTSVGIVPTQAIATGP 344

Query: 326 GAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSG 385
              TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+G
Sbjct: 345 ---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAG 401

Query: 386 KSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNP-SSLG 444
           K+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQQ IL     G+ N   S+G
Sbjct: 402 KACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVG 461

Query: 445 VGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMXXXXXXXXXXXXXXXXXXXXXGMR 504
            GQQ+A +LS  + IDPSS++RAYAALGLPY +NQ                       MR
Sbjct: 462 TGQQNATSLSNPNPIDPSSMQRAYAALGLPY-MNQ-PQTQLQPQVPGQQPAQPQTHQQMR 519

Query: 505 PMSNMSASPMGVNGG---VGVQTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMPT 558
            ++ +  +PM +  G      Q P+L+S+S L +++ + NP+M   S + ++ +L  +PT
Sbjct: 520 TLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPT 579

Query: 559 AAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGD 618
           AA PS+TG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGD
Sbjct: 580 AAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGD 639

Query: 619 MYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSXXXXXXXXXX 678
           MYESAN+R EYYHLLAEKIYKIQKELEEKRR+RL KQ +L N   + P            
Sbjct: 640 MYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPAL-PAPGAQPPVIPQA 698

Query: 679 XXXXTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMA-----QPPIVPRQTPPL 733
                 NGPL  P           + R+    G+N F  MS+      Q P+ PR   P+
Sbjct: 699 QPVRPPNGPLSLP-----------VNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPM 747

Query: 734 QHHGQLAQPGALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQGMNV 777
            H  Q+   G++ P M   P RM QP N               Q QFLPQ QFPS     
Sbjct: 748 NHSVQMNSMGSV-PGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSS-GA 805

Query: 778 TNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALH 828
            ++ +     Q  VSQ Q+  ++ P  +P+   G Q S + CP + Q  LH
Sbjct: 806 MSVGMGQPPAQTGVSQGQVPGAALP--NPLNMLGPQASQLPCPPVTQSPLH 854




 Score = 65.5 bits (158), Expect = 1e-08
 Identities = 39/108 (36%), Positives = 48/108 (44%)

Query: 2269 MGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNXXXXXXXXXXXXXXXXXXXXXXX 2328
            +GSP QPNPMSPQQHML  Q Q+ HL GQQI  SLSN                       
Sbjct: 2305 IGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPS 2364

Query: 2329 XXXXXXXXXXXXXXXXXXXXXGLVAAQANPMEQGHFASPDQNSMLSQL 2376
                                 GL    A+ ++QGH  +P+Q++ML QL
Sbjct: 2365 PRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQL 2412




 Score = 59.3 bits (142), Expect = 8e-07
 Identities = 53/183 (28%), Positives = 74/183 (40%), Gaps = 29/183 (15%)

Query: 2010 MPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNXXXXXXXXXXXXXXXX 2069
            +PRP +   AQ       A   G     + P  P ++S  ALQ+                
Sbjct: 2035 LPRPVISMQAQ-------AAVAGPRMPSVQP--PRSISPSALQDLLRTLKSPSSPQQQQQ 2085

Query: 2070 XXXXXHANPQLLAAFIKQRAAKYANSNXXXXXXXXXXXXXXXXXXXXXXXXXXXVHSNPA 2129
                  +NPQL+AAFIKQR AKY  +                            +H  P+
Sbjct: 2086 VLNILKSNPQLMAAFIKQRTAKYVANQ-------PGMQPQPGLQSQPGMQPQPGMHQQPS 2138

Query: 2130 MQNMNPMQAGVQRAGXXXXXXXXXXXXXMGGMSPQAQQMNM-------NHNTMPSQFRDI 2182
            +QN+N MQAGV R G             MGG++PQ Q +N+       N  +M  Q+R++
Sbjct: 2139 LQNLNAMQAGVPRPG------VPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREM 2192

Query: 2183 LRR 2185
            LRR
Sbjct: 2193 LRR 2195



>gi|4758056|ref|NP_004371.1| CREB binding protein [Homo sapiens]
 gi|3023440|sp|Q92793|CBP_HUMAN CREB-binding protein
 gi|2443859|gb|AAC51770.1| CREB-binding protein
          Length = 2442

 Score = 1234 bits (3194), Expect = 0.0
 Identities = 654/881 (74%), Positives = 708/881 (80%), Gaps = 16/881 (1%)

Query: 946  SIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDC 1005
            SI+ +V  P S +S E NSQ      P  E+K E + E  +P+P +++ E  SE   ED 
Sbjct: 967  SIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDL 1026

Query: 1006 KMXXXXXXXXXXXXXXXIKEEED---------------XXXXXXXXXXXXXGQSKKKIFK 1050
            +                   E D                             Q +KKIFK
Sbjct: 1027 QGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFK 1086

Query: 1051 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQ 1110
            PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK+PMDLSTIKRKLDTGQ
Sbjct: 1087 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQ 1146

Query: 1111 YQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEF 1170
            YQEPWQYVDD+WLMFNNAWLYNRKTSRVYK+CSKL+EVFEQEIDPVMQSLGYCCGRK EF
Sbjct: 1147 YQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEF 1206

Query: 1171 SPQTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQ 1230
            SPQTLCCYGKQLCTIPRDA YYSYQNRYHFCEKCF EIQGE+V+LGDDPSQPQTTI+K+Q
Sbjct: 1207 SPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQ 1266

Query: 1231 FSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSA 1290
            F K+KNDTLDPE FV+C ECGRKMHQICVLH++IIWP+GFVCD CLKK+ R RKENKFSA
Sbjct: 1267 FEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSA 1326

Query: 1291 KRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMA 1350
            KRL +TRLG  LE+RVN FLRRQNHPE+GEV VRVV +SDKTVEVKPGMK+RFVDSGEM+
Sbjct: 1327 KRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMS 1386

Query: 1351 ESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLR 1410
            ESFPYRTKALFAFEEIDGVD+CFFGMHVQEYGSDCPPPN RRVYISYLDS+HFFRP+CLR
Sbjct: 1387 ESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLR 1446

Query: 1411 TAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM 1470
            TAVYHEILIGYLEYVKKLGY TGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM
Sbjct: 1447 TAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM 1506

Query: 1471 LDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNV-XXXXXXXXXXXXXXXXX 1529
            LDKA +ERI+HDYKDIFKQATEDRLTSAKELPYFEGDFWPNV                  
Sbjct: 1507 LDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKE 1566

Query: 1530 XXXXXXXSTDVTKGDXXXXXXXXXXXXXXXXXXLSRGNKKKPGMPNVSNDLSQKLYATME 1589
                   +T+ ++GD                  +SR NKKKP MPNVSNDLSQKLYATME
Sbjct: 1567 ESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATME 1626

Query: 1590 KHKEVFFVIRLIAGPAANSXXXXXXXXXXXXXXXMDGRDAFLTLARDKHLEFSSLRRAQW 1649
            KHKEVFFVI L AGP  N+               MDGRDAFLTLARDKH EFSSLRR++W
Sbjct: 1627 KHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKW 1686

Query: 1650 STMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLG 1709
            ST+CMLVELHTQ QDRFVYTCNECKHHVETRWHCTVCEDYDLCI CYNTK+H HKM K G
Sbjct: 1687 STLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWG 1746

Query: 1710 LGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK 1769
            LGLDDE ++Q    ++SP +SRR+SIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK
Sbjct: 1747 LGLDDEGSSQGEPQSKSPQESRRVSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK 1806

Query: 1770 GCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIK 1810
            GCKRKTNGGCP+CKQLIALCCYHAKHCQENKCPVPFCLNIK
Sbjct: 1807 GCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIK 1847




 Score =  560 bits (1444), Expect = e-157
 Identities = 409/891 (45%), Positives = 514/891 (57%), Gaps = 100/891 (11%)

Query: 1   MAENVVEPGPPSAKRPKXXXXXXXXXXXDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG 59
           MAEN+++ GPP+ KR K           D TDFGSLFDLE+DLPDELI N  ELGL N G
Sbjct: 1   MAENLLD-GPPNPKRAK--LSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSG 57

Query: 60  DINQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGG--------PGQVMASQAQQS 111
           +         +V DAASKHKQLSELLR GS  ++N G+G          G    +Q Q +
Sbjct: 58  N---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN 108

Query: 112 SPGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQ 160
           S  +  +++M KSP++Q   ++P++      TSGP    +Q+         G+  S    
Sbjct: 109 SANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT 168

Query: 161 PAMGMNTGTNAGMN---PGMLAAGNGQGIMPN------QVMNGSI--GAGRGRQDMQYPN 209
              G     NA  N   PG+L + +G  ++        QVMNGS+          M YP 
Sbjct: 169 SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPT 228

Query: 210 PGM-GSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQI 265
           P M G++ ++L E L Q SPQM G  GL   Q     KMG+  N +P+G P++Q  GQ +
Sbjct: 229 PAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPM 288

Query: 266 GASGLGLQIQTKTVLSNNLSPFAMDKKAVXXXXXXXXXXXXXXXXXXXGLVTPVAQGMGS 325
           GA+G+  Q+ +K  + N+L  F  D K                     G+V   A   G 
Sbjct: 289 GATGVNPQLASKQSMVNSLPTFPTDIKNT----SVTNVPNMSQMQTSVGIVPTQAIATGP 344

Query: 326 GAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSG 385
              TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+G
Sbjct: 345 ---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAG 401

Query: 386 KSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNP-SSLG 444
           K+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQQ IL     G+ N   S+G
Sbjct: 402 KACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVG 461

Query: 445 VGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMXXXXXXXXXXXXXXXXXXXXXGMR 504
            GQQ+A +LS  + IDPSS++RAYAALGLPY +NQ                       MR
Sbjct: 462 TGQQNATSLSNPNPIDPSSMQRAYAALGLPY-MNQ-PQTQLQPQVPGQQPAQPQTHQQMR 519

Query: 505 PMSNMSASPMGVNGG---VGVQTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMPT 558
            ++ +  +PM +  G      Q P+L+S+S L +++ + NP+M   S + ++ +L  +PT
Sbjct: 520 TLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPT 579

Query: 559 AAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGD 618
           AA PS+TG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGD
Sbjct: 580 AAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGD 639

Query: 619 MYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSXXXXXXXXXX 678
           MYESAN+R EYYHLLAEKIYKIQKELEEKRR+RL KQ +L N   + P            
Sbjct: 640 MYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPAL-PAPGAQPPVIPQA 698

Query: 679 XXXXTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMA-----QPPIVPRQTPPL 733
                 NGPL  P           + R+    G+N F  MS+      Q P+ PR   P+
Sbjct: 699 QPVRPPNGPLSLP-----------VNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPM 747

Query: 734 QHHGQLAQPGALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQGMNV 777
            H  Q+   G++ P M   P RM QP N               Q QFLPQ QFPS     
Sbjct: 748 NHSVQMNSMGSV-PGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSS-GA 805

Query: 778 TNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALH 828
            ++ +     Q  VSQ Q+  ++ P  +P+   G Q S + CP + Q  LH
Sbjct: 806 MSVGMGQPPAQTGVSQGQVPGAALP--NPLNMLGPQASQLPCPPVTQSPLH 854




 Score = 65.5 bits (158), Expect = 1e-08
 Identities = 39/108 (36%), Positives = 48/108 (44%)

Query: 2269 MGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNXXXXXXXXXXXXXXXXXXXXXXX 2328
            +GSP QPNPMSPQQHML  Q Q+ HL GQQI  SLSN                       
Sbjct: 2305 IGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPS 2364

Query: 2329 XXXXXXXXXXXXXXXXXXXXXGLVAAQANPMEQGHFASPDQNSMLSQL 2376
                                 GL    A+ ++QGH  +P+Q++ML QL
Sbjct: 2365 PRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQL 2412




 Score = 59.3 bits (142), Expect = 8e-07
 Identities = 53/183 (28%), Positives = 74/183 (40%), Gaps = 29/183 (15%)

Query: 2010 MPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNXXXXXXXXXXXXXXXX 2069
            +PRP +   AQ       A   G     + P  P ++S  ALQ+                
Sbjct: 2035 LPRPVISMQAQ-------AAVAGPRMPSVQP--PRSISPSALQDLLRTLKSPSSPQQQQQ 2085

Query: 2070 XXXXXHANPQLLAAFIKQRAAKYANSNXXXXXXXXXXXXXXXXXXXXXXXXXXXVHSNPA 2129
                  +NPQL+AAFIKQR AKY  +                            +H  P+
Sbjct: 2086 VLNILKSNPQLMAAFIKQRTAKYVANQ-------PGMQPQPGLQSQPGMQPQPGMHQQPS 2138

Query: 2130 MQNMNPMQAGVQRAGXXXXXXXXXXXXXMGGMSPQAQQMNM-------NHNTMPSQFRDI 2182
            +QN+N MQAGV R G             MGG++PQ Q +N+       N  +M  Q+R++
Sbjct: 2139 LQNLNAMQAGVPRPG------VPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREM 2192

Query: 2183 LRR 2185
            LRR
Sbjct: 2193 LRR 2195



>gi|19547885|gb|AAL87531.1| CREB-binding protein [Mus musculus]
 gi|19547887|gb|AAL87532.1| CREB-binding protein [Mus musculus]
          Length = 2429

 Score = 1225 bits (3170), Expect = 0.0
 Identities = 650/881 (73%), Positives = 711/881 (80%), Gaps = 16/881 (1%)

Query: 946  SIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVED- 1004
            SI+ +V  P S +S E +SQ      P  E+K E + +  +PEP +++ E  SE   ED 
Sbjct: 962  SIDNRVPTPSSVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRSEMMEEDL 1021

Query: 1005 ---CKMXXXXXXXXXXXXXXXIKEEE-----------DXXXXXXXXXXXXXGQSKKKIFK 1050
                ++               ++E++           +              Q +KKIFK
Sbjct: 1022 QGSSQVKEETDTTEQKSEPMEVEEKKPEVKVEAKEEEENSSNDTASQSTSPSQPRKKIFK 1081

Query: 1051 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQ 1110
            PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK+PMDLSTIKRKLDTGQ
Sbjct: 1082 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQ 1141

Query: 1111 YQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEF 1170
            YQEPWQYVDD+WLMFNNAWLYNRKTSRVYK+CSKL+EVFEQEIDPVMQSLGYCCGRK EF
Sbjct: 1142 YQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEF 1201

Query: 1171 SPQTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQ 1230
            SPQTLCCYGKQLCTIPRDA YYSYQNRYHFCEKCF EIQGE+V+LGDDPSQPQTTI+K+Q
Sbjct: 1202 SPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQ 1261

Query: 1231 FSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSA 1290
            F K+KNDTLDPE FV+C ECGRKMHQICVLH++IIWP+GFVCD CLKK+ R RKENKFSA
Sbjct: 1262 FEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSA 1321

Query: 1291 KRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMA 1350
            KRL +TRLG  LE+RVN FLRRQNHPE+GEV VRVV +SDKTVEVKPGMK+RFVDSGEM+
Sbjct: 1322 KRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMS 1381

Query: 1351 ESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLR 1410
            ESFPYRTKALFAFEEIDGVD+CFFGMHVQEYGSDCPPPN RRVYISYLDS+HFFRP+CLR
Sbjct: 1382 ESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLR 1441

Query: 1411 TAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM 1470
            TAVYHEILIGYLEYVKKLGY TGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM
Sbjct: 1442 TAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM 1501

Query: 1471 LDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVXXXXXXXXXXXXXXXXXX 1530
            LDKA +ERI++DYKDIFKQA EDRLTSAKELPYFEGDFWPNV                  
Sbjct: 1502 LDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKE 1561

Query: 1531 XXXXXXST-DVTKGDXXXXXXXXXXXXXXXXXXLSRGNKKKPGMPNVSNDLSQKLYATME 1589
                   T + ++GD                  +SR NKKKP MPNVSNDLSQKLYATME
Sbjct: 1562 ESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATME 1621

Query: 1590 KHKEVFFVIRLIAGPAANSXXXXXXXXXXXXXXXMDGRDAFLTLARDKHLEFSSLRRAQW 1649
            KHKEVFFVI L AGP  ++               MDGRDAFLTLARDKH EFSSLRR++W
Sbjct: 1622 KHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKW 1681

Query: 1650 STMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLG 1709
            ST+CMLVELHTQ QDRFVYTCNECKHHVETRWHCTVCEDYDLCI CYNTK+H HKM K G
Sbjct: 1682 STLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKWG 1741

Query: 1710 LGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK 1769
            LGLDDE ++Q    ++SP +SRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK
Sbjct: 1742 LGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK 1801

Query: 1770 GCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIK 1810
            GCKRKTNGGCP+CKQLIALCCYHAKHCQENKCPVPFCLNIK
Sbjct: 1802 GCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIK 1842




 Score =  568 bits (1464), Expect = e-160
 Identities = 410/884 (46%), Positives = 509/884 (57%), Gaps = 99/884 (11%)

Query: 9   GPPSAKRPKXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGDINQLQTSL 68
           GPP+ KR K           D TDFGSLFDLE+DLPDELI + EL L N G+        
Sbjct: 2   GPPNPKRAK--LSSPGFSANDNTDFGSLFDLENDLPDELIPNGELSLLNSGN-------- 51

Query: 69  GMVQDAASKHKQLSELLRSGSSPNLNMGVGG--------PGQVMASQAQQSSPGLGLINS 120
            +V DAASKHKQLSELLR GS  ++N G+G          G    +Q Q +S  +  + +
Sbjct: 52  -LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSTNMASLGA 110

Query: 121 MVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQPAMGMNTGT 169
           M KSP+ Q   ++PN+      TSGP    +Q+         G++ S       G     
Sbjct: 111 MGKSPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICM 170

Query: 170 NAGMN---PGMLAAGNGQGIMPN------QVMNGSI--GAGRGRQDMQYPNPGM-GSAGN 217
           NA  N   PG+L + +G  +M        QVMNGS+          M YP P M G+  +
Sbjct: 171 NANFNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLGAAGRGRGAGMPYPAPAMQGATSS 230

Query: 218 LLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQI 274
           +L E L Q SPQM G  GL   Q     KMGM    +P+G P++Q  GQQ+GA+G+  Q+
Sbjct: 231 VLAETLTQVSPQMAGHAGLNTAQAGGMTKMGMTGTTSPFGQPFSQTGGQQMGATGVNPQL 290

Query: 275 QTKTVLSNNLSPFAMDKKAVXXXXXXXXXXXXXXXXXXXGLVTPVAQGMGSGAHTADPEK 334
            +K  + N+L  F  D K                     G+V   A   G    TADPEK
Sbjct: 291 ASKQSMVNSLPAFPTDIKNT----SVTTVPNMSQLQTSVGIVPTQAIATGP---TADPEK 343

Query: 335 RKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCA 394
           RKLIQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+GK+CQVAHCA
Sbjct: 344 RKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCA 403

Query: 395 SSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNP-SSLGVGQQSAPNL 453
           SSRQIISHWKNCTRHDCPVCLPLKNA DKRNQQ IL     G+ N   S+G GQQ+A +L
Sbjct: 404 SSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSL 463

Query: 454 STVSQIDPSSIERAYAALGLPYQVNQMXXXXXXXXXXXXXXXXXXXXXGMRPMSNMSASP 513
           S  + IDPSS++RAYAALGLPY +NQ                       MR ++ +  +P
Sbjct: 464 SNPNPIDPSSMQRAYAALGLPY-MNQ-PQTQLQPQVPGQQPAQPPAHQQMRTLNALGNNP 521

Query: 514 MGVNGG---VGVQTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMPTAAQPSTTGI 567
           M +  G      Q P+L+S+S L +++ + NP+M   S + ++ SL  +PTAA PS+TG+
Sbjct: 522 MSIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGV 581

Query: 568 RKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRA 627
           RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGDMYESAN+R 
Sbjct: 582 RKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRD 641

Query: 628 EYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSXXXXXXXXXXXXXXTSNGP 687
           EYYHLLAEKIYKIQKELEEKRR+RL KQ +L N   + P S                NGP
Sbjct: 642 EYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPAL-PASGAQPPVIPPAQSVRPPNGP 700

Query: 688 LPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMA-----QPPIVPRQTPPLQHHGQLAQP 742
           LP P           + R+    G+N F  MS+      Q P+ PR   P+ H  Q+   
Sbjct: 701 LPLP-----------VNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSM 749

Query: 743 GALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQ--GMNVTNIPLAP 784
            ++ P M   P RM QP N               Q QFLPQ QFPS    M+V ++ +  
Sbjct: 750 ASV-PGMAISPSRMPQPPNMMGTHANNIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQ 808

Query: 785 SSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALH 828
            + QA VSQ Q+  ++ P  +P+     Q S + CP + Q  LH
Sbjct: 809 PAAQAGVSQGQVPGAALP--NPLNMLAPQASQLPCPPVTQSPLH 850




 Score = 67.0 bits (162), Expect = 4e-09
 Identities = 40/108 (37%), Positives = 48/108 (44%)

Query: 2269 MGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNXXXXXXXXXXXXXXXXXXXXXXX 2328
            +GSP QPNPMSPQQHML  Q Q+ HL GQQI  SLSN                       
Sbjct: 2298 IGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPS 2357

Query: 2329 XXXXXXXXXXXXXXXXXXXXXGLVAAQANPMEQGHFASPDQNSMLSQL 2376
                                 GL    A+ M+QGH  +P+Q++ML QL
Sbjct: 2358 PRIQPQPSPHHVSPQTGSPHPGLAVTMASSMDQGHLGNPEQSAMLPQL 2405




 Score = 52.4 bits (124), Expect = 1e-04
 Identities = 50/183 (27%), Positives = 69/183 (37%), Gaps = 29/183 (15%)

Query: 2010 MPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNXXXXXXXXXXXXXXXX 2069
            MPRP M   AQ       A   G     + P  P ++S  ALQ+                
Sbjct: 2030 MPRPVMSMQAQ-------AAVAGPRMPNVQP--PRSISPSALQDLLRTLKSPSSPQQQQQ 2080

Query: 2070 XXXXXHANPQLLAAFIKQRAAKYANSNXXXXXXXXXXXXXXXXXXXXXXXXXXXVHSNPA 2129
                  +NPQL+AAFIKQR AKY  +                            +H  P+
Sbjct: 2081 VLNILKSNPQLMAAFIKQRTAKYVANQ-------PGMQPQPGLQSQPGMQPQPGMHQQPS 2133

Query: 2130 MQNMNPMQAGVQRAGXXXXXXXXXXXXXMGGMSPQAQQMNM-------NHNTMPSQFRDI 2182
            +QN+N MQA                   MGG++PQ Q +N+       N   M  Q+R++
Sbjct: 2134 LQNLNAMQA------GVPRPGVPPPQPAMGGLNPQGQALNIMNPGHNPNMTNMNPQYREM 2187

Query: 2183 LRR 2185
            +RR
Sbjct: 2188 VRR 2190



>gi|631119|pir||S39162 transcription coactivator CREB-binding protein - human
          Length = 2440

 Score = 1196 bits (3094), Expect = 0.0
 Identities = 642/881 (72%), Positives = 699/881 (79%), Gaps = 16/881 (1%)

Query: 946  SIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDC 1005
            SI+ +V  P + +S E NSQ      P  E+K E + E  +P+P +++ E  SE   ED 
Sbjct: 967  SIDNRVPTPSTVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDL 1026

Query: 1006 ---------------KMXXXXXXXXXXXXXXXIKEEEDXXXXXXXXXXXXXGQSKKKIFK 1050
                           K                +KEEE+              Q +KKIFK
Sbjct: 1027 QGASQVKEETDIAEQKSEPMEVEDKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFK 1086

Query: 1051 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQ 1110
            PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK+PMDLSTIKRKLDTGQ
Sbjct: 1087 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQ 1146

Query: 1111 YQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEF 1170
            YQEPWQYVDD+WLMFNNAWLYNRKTSRVYK+CSKL+EVFEQEIDPVMQSLGYCCGRK EF
Sbjct: 1147 YQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEF 1206

Query: 1171 SPQTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQ 1230
            SPQTLCCYGKQLCTIPRDA YYSYQNRYHFCEKCF EIQGE+V+LGDDPSQPQTTI+K+Q
Sbjct: 1207 SPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQ 1266

Query: 1231 FSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSA 1290
            F K+KNDTLDPE FV+C ECGRKMHQICVLH++IIWP+GFVCD CLKK+ R RKENKFSA
Sbjct: 1267 FEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSA 1326

Query: 1291 KRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMA 1350
            KRL +TRLG  LE+RVN FLRRQNHPE+GEV VRVV +SDKTVEVKPGMK+RFVDSGEM+
Sbjct: 1327 KRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMS 1386

Query: 1351 ESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLR 1410
            ESFPYRTKALFAFEEIDGVD+CFFGMHVQ+     P   Q  VYISYLDS+HFFRP+CLR
Sbjct: 1387 ESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSIHFFRPRCLR 1446

Query: 1411 TAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM 1470
            TAVYHEILIGYLEYVKKL Y T HIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM
Sbjct: 1447 TAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM 1506

Query: 1471 LDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVXXXXXXXXXXXXXXXXXX 1530
            LDKA +ERI++DYKDIFKQA EDRLTSAKELPYFEGDFWPNV                  
Sbjct: 1507 LDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKE 1566

Query: 1531 XXXXXXST-DVTKGDXXXXXXXXXXXXXXXXXXLSRGNKKKPGMPNVSNDLSQKLYATME 1589
                   T + ++GD                  +SR NKKKP MPNVSNDLSQKLYATME
Sbjct: 1567 ESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATME 1626

Query: 1590 KHKEVFFVIRLIAGPAANSXXXXXXXXXXXXXXXMDGRDAFLTLARDKHLEFSSLRRAQW 1649
            KHKEVFFVI L AGP  ++               MDGRDAFLTLARDKH EFSSLRR++W
Sbjct: 1627 KHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKW 1686

Query: 1650 STMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLG 1709
            ST+CMLVELHTQ QDRFVYTCNECKHHVETRWHCTVCEDYDLCI CYNTK+H HKM K G
Sbjct: 1687 STLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKWG 1746

Query: 1710 LGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK 1769
            LGLDDE ++Q    ++SP +SRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK
Sbjct: 1747 LGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK 1806

Query: 1770 GCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIK 1810
            GCKRKTNGGCP+CKQLIALCCYHAKHCQENKCPVPFCLNIK
Sbjct: 1807 GCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIK 1847




 Score =  553 bits (1424), Expect = e-155
 Identities = 406/891 (45%), Positives = 510/891 (57%), Gaps = 100/891 (11%)

Query: 1   MAENVVEPGPPSAKRPKXXXXXXXXXXXDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG 59
           MAEN+++ GPP+ KR K             TDFGSLFDLE+DLPDELI N  ELGL N G
Sbjct: 1   MAENLLD-GPPNPKRAK--LSSPGFSANSNTDFGSLFDLENDLPDELIPNGGELGLLNSG 57

Query: 60  DINQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGG--------PGQVMASQAQQS 111
           +         +V DAASKHKQLSELLR GS  ++N G+G          G    +Q Q +
Sbjct: 58  N---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN 108

Query: 112 SPGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQ 160
           S  +  +++M KSP++Q   +SP++      TSGP    +Q+         G+  S    
Sbjct: 109 SANMASLSAMGKSPLSQGDSSSPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT 168

Query: 161 PAMGMNTGTNAGMN---PGMLAAGNGQGIMPN------QVMNGSI--GAGRGRQDMQYPN 209
              G     NA  N   PG+L + +G  ++        QVMNGS+          M Y  
Sbjct: 169 SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYTA 228

Query: 210 PGM-GSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQI 265
           P M G++ ++L E L Q SPQ  G  GL   Q     K+GM    +P+G P++Q  GQ +
Sbjct: 229 PAMQGASSSVLAETLTQVSPQTAGHAGLNTAQAGGMAKIGMNGTTSPFGQPFSQAGGQPM 288

Query: 266 GASGLGLQIQTKTVLSNNLSPFAMDKKAVXXXXXXXXXXXXXXXXXXXGLVTPVAQGMGS 325
           GA+G+  Q+ +K  + N+L  F  D K                     G+V   A   G 
Sbjct: 289 GATGVNPQLASKQSMVNSLPTFPTDIKNT----SVTNVPNMSQMQTSVGIVPTQAIATGP 344

Query: 326 GAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSG 385
              TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+G
Sbjct: 345 ---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAG 401

Query: 386 KSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNP-SSLG 444
           K+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQQ IL     G+ N   S+G
Sbjct: 402 KACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVG 461

Query: 445 VGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMXXXXXXXXXXXXXXXXXXXXXGMR 504
            GQQ+A +LS  + IDPSS++RAYAALGLPY +NQ                       MR
Sbjct: 462 TGQQNATSLSNPNPIDPSSMQRAYAALGLPY-MNQ-PQTQLQPQVPGQQPAQPQTHQQMR 519

Query: 505 PMSNMSASPMGVNGG---VGVQTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMPT 558
            ++ +  +PM +  G      Q P+L+S+S L +++ + NP+M   S + ++ +L  +PT
Sbjct: 520 TLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPT 579

Query: 559 AAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGD 618
           AA PS+TG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGD
Sbjct: 580 AAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGD 639

Query: 619 MYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSXXXXXXXXXX 678
           MYESAN+R EYYHLLAEKIYKIQKELEEKRR+RL KQ +L N   + P            
Sbjct: 640 MYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPAL-PAPGAQPPVIPQA 698

Query: 679 XXXXTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMA-----QPPIVPRQTPPL 733
                 NGPL  P           + R+    G+N F  MS+      Q P+ PR   P+
Sbjct: 699 QSVRPPNGPLSLP-----------VNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPM 747

Query: 734 QHHGQLAQPGALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQGMNV 777
            H  Q+   G++ P M   P RM QP N               Q QFLPQ QFPS     
Sbjct: 748 NHSVQMNSMGSV-PGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSS-GA 805

Query: 778 TNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALH 828
            ++ +     Q  VSQ Q+  ++ P  +P+   G Q S + CP + Q  LH
Sbjct: 806 MSVGMGQPPAQTGVSQGQVPGAALP--NPLNMLGPQASQLPCPPVTQSPLH 854




 Score = 67.4 bits (163), Expect = 3e-09
 Identities = 40/108 (37%), Positives = 48/108 (44%)

Query: 2269 MGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNXXXXXXXXXXXXXXXXXXXXXXX 2328
            +GSP QPNPMSPQQHML  Q Q+ HL GQQI  SLSN                       
Sbjct: 2303 IGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPS 2362

Query: 2329 XXXXXXXXXXXXXXXXXXXXXGLVAAQANPMEQGHFASPDQNSMLSQL 2376
                                 GL    A+ M+QGH  +P+Q++ML QL
Sbjct: 2363 PRIQPQPSPHHVSPQTGTPHPGLAVTMASSMDQGHLGNPEQSAMLPQL 2410




 Score = 50.4 bits (119), Expect = 4e-04
 Identities = 49/183 (26%), Positives = 69/183 (37%), Gaps = 29/183 (15%)

Query: 2010 MPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNXXXXXXXXXXXXXXXX 2069
            MPRP M   AQ       A   G     + P +  ++S  ALQ+                
Sbjct: 2035 MPRPVMSMQAQ-------AAVAGPRMPNVQPNR--SISPSALQDLLRTLKSPSSPQQQQQ 2085

Query: 2070 XXXXXHANPQLLAAFIKQRAAKYANSNXXXXXXXXXXXXXXXXXXXXXXXXXXXVHSNPA 2129
                  +NPQL+AAFIKQR AKY  +                            +H  P+
Sbjct: 2086 VLNILKSNPQLMAAFIKQRTAKYVANQ-------PGMQPQPGLQSQPGMQPQPGMHQQPS 2138

Query: 2130 MQNMNPMQAGVQRAGXXXXXXXXXXXXXMGGMSPQAQQMNM-------NHNTMPSQFRDI 2182
            +QN+N MQA                   MGG++PQ Q +N+       N   M  Q+R++
Sbjct: 2139 LQNLNAMQA------GVPRPGVPPPQPAMGGLNPQGQALNIMNPGHNPNMTNMNPQYREM 2192

Query: 2183 LRR 2185
            +RR
Sbjct: 2193 VRR 2195



>gi|737920|prf||1923401A protein CBP
          Length = 2441

 Score = 1186 bits (3068), Expect = 0.0
 Identities = 635/881 (72%), Positives = 698/881 (79%), Gaps = 16/881 (1%)

Query: 946  SIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVED- 1004
            SI+ +V  P + +S E +SQ      P  E+K E + +  +PEP +++ E  SE   ED 
Sbjct: 968  SIDNRVPTPSTVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRSEMMEEDL 1027

Query: 1005 ---CKMXXXXXXXXXXXXXXXIKEEE-----------DXXXXXXXXXXXXXGQSKKKIFK 1050
                ++               ++E++           +              Q +KKIFK
Sbjct: 1028 QGSSQVKEETDTTEQKSEPMEVEEKKPEVKVEAKEEEENSSNDTASQSTSPSQPRKKIFK 1087

Query: 1051 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQ 1110
            PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK+PMDLSTIKRKLDTGQ
Sbjct: 1088 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQ 1147

Query: 1111 YQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEF 1170
            YQEPWQYVDD+ LMFNNAWLYNRKTSRVYK+CSKL+EVFEQEIDPVMQSLGYCCGRK EF
Sbjct: 1148 YQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEF 1207

Query: 1171 SPQTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQ 1230
            SPQTLCCYGKQLCTIPRDA YYSYQNRYHFC KCF EIQGE+V+LGDDPSQPQTTI+K+Q
Sbjct: 1208 SPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCGKCFTEIQGENVTLGDDPSQPQTTISKDQ 1267

Query: 1231 FSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSA 1290
            F K+KNDTLDPE FV+C ECGRKMHQICVLH++IIWP+GFVCD CLKK+ R RKENKFSA
Sbjct: 1268 FEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSA 1327

Query: 1291 KRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMA 1350
            KRL +TRLG  LE+RVN FLRRQNHPE+GEV VRVV +SDKTVEVKPGMK+RFVDSGEM+
Sbjct: 1328 KRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMS 1387

Query: 1351 ESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLR 1410
            ESFPYRTKALFAFEEIDGVD+CFFGMHVQ+     P   Q  VYISYLDS+HFFRP+CLR
Sbjct: 1388 ESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSIHFFRPRCLR 1447

Query: 1411 TAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM 1470
            TAVYHEILIGYLEYVKKL Y T HIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM
Sbjct: 1448 TAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM 1507

Query: 1471 LDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVXXXXXXXXXXXXXXXXXX 1530
            LDKA +ERI++DYKDIFKQA EDRLTSAKELPYFEGDFWPNV                  
Sbjct: 1508 LDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKE 1567

Query: 1531 XXXXXXST-DVTKGDXXXXXXXXXXXXXXXXXXLSRGNKKKPGMPNVSNDLSQKLYATME 1589
                   T + ++GD                  +SR NKKKP MPNVSNDLSQKLYATME
Sbjct: 1568 ESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATME 1627

Query: 1590 KHKEVFFVIRLIAGPAANSXXXXXXXXXXXXXXXMDGRDAFLTLARDKHLEFSSLRRAQW 1649
            KHKEVFFVI L AGP  ++               MDGRDAFLTLARDKH EFSSLRR++W
Sbjct: 1628 KHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKW 1687

Query: 1650 STMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLG 1709
            ST+CMLVELHTQ QDRFVYTCNECKHHVETRWHCTVCEDYDLCI CYNTK+H HKM K G
Sbjct: 1688 STLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKWG 1747

Query: 1710 LGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK 1769
            LGLDDE ++Q    ++SP +SRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK
Sbjct: 1748 LGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK 1807

Query: 1770 GCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIK 1810
            GCKRKTNGGCP+CKQLIALCCYHAKHCQENKCPVPFCLNIK
Sbjct: 1808 GCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIK 1848




 Score =  570 bits (1470), Expect = e-160
 Identities = 415/892 (46%), Positives = 514/892 (57%), Gaps = 100/892 (11%)

Query: 1   MAENVVEPGPPSAKRPKXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
           MAEN+++ GPP+ KR K           D TDFGSLFDLE+DLPDELI + EL L N G+
Sbjct: 1   MAENLLD-GPPNPKRAK--LSSPGFSANDNTDFGSLFDLENDLPDELIPNGELSLLNSGN 57

Query: 61  INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGG--------PGQVMASQAQQSS 112
                    +V DAASKHKQLSELLR GS  ++N G+G          G    +Q Q +S
Sbjct: 58  ---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNS 108

Query: 113 PGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQP 161
             +  + +M KSP+ Q   ++PN+      TSGP    +Q+         G++ S     
Sbjct: 109 TNMASLGAMGKSPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATS 168

Query: 162 AMGMNTGTNAGMN---PGMLAAGNGQGIMPN------QVMNGSI--GAGRGRQDMQYPNP 210
             G     NA  N   PG+L + +G  +M        QVMNGS+          M YP P
Sbjct: 169 QTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLGAAGRGRGAGMPYPAP 228

Query: 211 GM-GSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQIG 266
            M G+  ++L E L Q SPQM G  GL   Q     KMGM    +P+G P++Q  GQQ+G
Sbjct: 229 AMQGATSSVLAETLTQVSPQMAGHAGLNTAQAGGMTKMGMTGTTSPFGQPFSQTGGQQMG 288

Query: 267 ASGLGLQIQTKTVLSNNLSPFAMDKKAVXXXXXXXXXXXXXXXXXXXGLVTPVAQGMGSG 326
           A+G+  Q+ +K  + N+L  F  D K                     G+V   A   G  
Sbjct: 289 ATGVNPQLASKQSMVNSLPAFPTDIKNT----SVTTVPNMSQLQTSVGIVPTQAIATGP- 343

Query: 327 AHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGK 386
             TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+ K
Sbjct: 344 --TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPK 401

Query: 387 SCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNP-SSLGV 445
           +CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQQ IL     G+ N   S+G 
Sbjct: 402 ACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGA 461

Query: 446 GQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMXXXXXXXXXXXXXXXXXXXXXGMRP 505
           GQQ+A +LS  + IDPSS++RAYAALGLPY +NQ                       MR 
Sbjct: 462 GQQNATSLSNPNPIDPSSMQRAYAALGLPY-MNQ-PQTQLQPQVPGQQPAQPPAHQQMRT 519

Query: 506 MSNMSASPMGVNGG---VGVQTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMPTA 559
           ++ +  +PM V  G      Q P+L+S+S L +++ + NP+M   S + ++ SL  +PTA
Sbjct: 520 LNALGNNPMSVPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTA 579

Query: 560 AQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDM 619
           A PS+TG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGDM
Sbjct: 580 APPSSTGVRKGWHERVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDM 639

Query: 620 YESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSXXXXXXXXXXX 679
           YESAN+R EYYHLLAEKIYKIQKELEEKRRTRL KQ +L N   + P S           
Sbjct: 640 YESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPAL-PASGAQPPVIPPAQ 698

Query: 680 XXXTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMA-----QPPIVPRQTPPLQ 734
                NGPLP P           + R+    G+N F  MS+      Q P+ PR   P+ 
Sbjct: 699 SVRPPNGPLPLP-----------VNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMN 747

Query: 735 HHGQLAQPGALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQ--GMN 776
           H  Q+    ++ P M   P RM QP N               Q QFLPQ QFPS    M+
Sbjct: 748 HSVQMNSMASV-PGMAISPSRMPQPPNMMGTHANNIMAQAPTQNQFLPQNQFPSSSGAMS 806

Query: 777 VTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALH 828
           V ++ +   + QA VSQ Q   ++ P  +P+     Q S + CP + Q  LH
Sbjct: 807 VNSVGMGQPAAQAGVSQGQEPGAALP--NPLNMLAPQASQLPCPPVTQSPLH 856




 Score = 67.0 bits (162), Expect = 4e-09
 Identities = 40/108 (37%), Positives = 48/108 (44%)

Query: 2269 MGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNXXXXXXXXXXXXXXXXXXXXXXX 2328
            +GSP QPNPMSPQQHML  Q Q+ HL GQQI  SLSN                       
Sbjct: 2304 IGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPS 2363

Query: 2329 XXXXXXXXXXXXXXXXXXXXXGLVAAQANPMEQGHFASPDQNSMLSQL 2376
                                 GL    A+ M+QGH  +P+Q++ML QL
Sbjct: 2364 PRIQPQPSPHHVSPQTGTPHPGLAVTMASSMDQGHLGNPEQSAMLPQL 2411




 Score = 50.4 bits (119), Expect = 4e-04
 Identities = 49/183 (26%), Positives = 69/183 (37%), Gaps = 29/183 (15%)

Query: 2010 MPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNXXXXXXXXXXXXXXXX 2069
            MPRP M   AQ       A   G     + P +  ++S  ALQ+                
Sbjct: 2036 MPRPVMSMQAQ-------AAVAGPRMPNVQPNR--SISPSALQDLLRTLKSPSSPQQQQQ 2086

Query: 2070 XXXXXHANPQLLAAFIKQRAAKYANSNXXXXXXXXXXXXXXXXXXXXXXXXXXXVHSNPA 2129
                  +NPQL+AAFIKQR AKY  +                            +H  P+
Sbjct: 2087 VLNILKSNPQLMAAFIKQRTAKYVANQ-------PGMQPQPGLQSQPGMQPQPGMHQQPS 2139

Query: 2130 MQNMNPMQAGVQRAGXXXXXXXXXXXXXMGGMSPQAQQMNM-------NHNTMPSQFRDI 2182
            +QN+N MQA                   MGG++PQ Q +N+       N   M  Q+R++
Sbjct: 2140 LQNLNAMQA------GVPRPGVPPPQPAMGGLNPQGQALNIMNPGHNPNMTNMNPQYREM 2193

Query: 2183 LRR 2185
            +RR
Sbjct: 2194 VRR 2196



>gi|1345703|sp|P45481|CBP_MOUSE CREB-binding protein
 gi|481698|pir||S39161 CREB-binding protein - mouse
 gi|435855|gb|AAB28651.1| CREB-binding protein; CBP [Mus sp.]
          Length = 2441

 Score = 1186 bits (3068), Expect = 0.0
 Identities = 635/881 (72%), Positives = 698/881 (79%), Gaps = 16/881 (1%)

Query: 946  SIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVED- 1004
            SI+ +V  P + +S E +SQ      P  E+K E + +  +PEP +++ E  SE   ED 
Sbjct: 968  SIDNRVPTPSTVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRSEMMEEDL 1027

Query: 1005 ---CKMXXXXXXXXXXXXXXXIKEEE-----------DXXXXXXXXXXXXXGQSKKKIFK 1050
                ++               ++E++           +              Q +KKIFK
Sbjct: 1028 QGSSQVKEETDTTEQKSEPMEVEEKKPEVKVEAKEEEENSSNDTASQSTSPSQPRKKIFK 1087

Query: 1051 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQ 1110
            PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK+PMDLSTIKRKLDTGQ
Sbjct: 1088 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQ 1147

Query: 1111 YQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEF 1170
            YQEPWQYVDD+ LMFNNAWLYNRKTSRVYK+CSKL+EVFEQEIDPVMQSLGYCCGRK EF
Sbjct: 1148 YQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEF 1207

Query: 1171 SPQTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQ 1230
            SPQTLCCYGKQLCTIPRDA YYSYQNRYHFC KCF EIQGE+V+LGDDPSQPQTTI+K+Q
Sbjct: 1208 SPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCGKCFTEIQGENVTLGDDPSQPQTTISKDQ 1267

Query: 1231 FSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSA 1290
            F K+KNDTLDPE FV+C ECGRKMHQICVLH++IIWP+GFVCD CLKK+ R RKENKFSA
Sbjct: 1268 FEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSA 1327

Query: 1291 KRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMA 1350
            KRL +TRLG  LE+RVN FLRRQNHPE+GEV VRVV +SDKTVEVKPGMK+RFVDSGEM+
Sbjct: 1328 KRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMS 1387

Query: 1351 ESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLR 1410
            ESFPYRTKALFAFEEIDGVD+CFFGMHVQ+     P   Q  VYISYLDS+HFFRP+CLR
Sbjct: 1388 ESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSIHFFRPRCLR 1447

Query: 1411 TAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM 1470
            TAVYHEILIGYLEYVKKL Y T HIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM
Sbjct: 1448 TAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM 1507

Query: 1471 LDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVXXXXXXXXXXXXXXXXXX 1530
            LDKA +ERI++DYKDIFKQA EDRLTSAKELPYFEGDFWPNV                  
Sbjct: 1508 LDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKE 1567

Query: 1531 XXXXXXST-DVTKGDXXXXXXXXXXXXXXXXXXLSRGNKKKPGMPNVSNDLSQKLYATME 1589
                   T + ++GD                  +SR NKKKP MPNVSNDLSQKLYATME
Sbjct: 1568 ESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATME 1627

Query: 1590 KHKEVFFVIRLIAGPAANSXXXXXXXXXXXXXXXMDGRDAFLTLARDKHLEFSSLRRAQW 1649
            KHKEVFFVI L AGP  ++               MDGRDAFLTLARDKH EFSSLRR++W
Sbjct: 1628 KHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKW 1687

Query: 1650 STMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLG 1709
            ST+CMLVELHTQ QDRFVYTCNECKHHVETRWHCTVCEDYDLCI CYNTK+H HKM K G
Sbjct: 1688 STLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKWG 1747

Query: 1710 LGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK 1769
            LGLDDE ++Q    ++SP +SRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK
Sbjct: 1748 LGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTK 1807

Query: 1770 GCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIK 1810
            GCKRKTNGGCP+CKQLIALCCYHAKHCQENKCPVPFCLNIK
Sbjct: 1808 GCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIK 1848




 Score =  570 bits (1470), Expect = e-161
 Identities = 415/892 (46%), Positives = 514/892 (57%), Gaps = 100/892 (11%)

Query: 1   MAENVVEPGPPSAKRPKXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
           MAEN+++ GPP+ KR K           D TDFGSLFDLE+DLPDELI + EL L N G+
Sbjct: 1   MAENLLD-GPPNPKRAK--LSSPGFSANDNTDFGSLFDLENDLPDELIPNGELSLLNSGN 57

Query: 61  INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGG--------PGQVMASQAQQSS 112
                    +V DAASKHKQLSELLR GS  ++N G+G          G    +Q Q +S
Sbjct: 58  ---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNS 108

Query: 113 PGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQP 161
             +  + +M KSP+ Q   ++PN+      TSGP    +Q+         G++ S     
Sbjct: 109 TNMASLGAMGKSPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATS 168

Query: 162 AMGMNTGTNAGMN---PGMLAAGNGQGIMPN------QVMNGSI--GAGRGRQDMQYPNP 210
             G     NA  N   PG+L + +G  +M        QVMNGS+          M YP P
Sbjct: 169 QTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLGAAGRGRGAGMPYPAP 228

Query: 211 GM-GSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQIG 266
            M G+  ++L E L Q SPQM G  GL   Q     KMGM    +P+G P++Q  GQQ+G
Sbjct: 229 AMQGATSSVLAETLTQVSPQMAGHAGLNTAQAGGMTKMGMTGTTSPFGQPFSQTGGQQMG 288

Query: 267 ASGLGLQIQTKTVLSNNLSPFAMDKKAVXXXXXXXXXXXXXXXXXXXGLVTPVAQGMGSG 326
           A+G+  Q+ +K  + N+L  F  D K                     G+V   A   G  
Sbjct: 289 ATGVNPQLASKQSMVNSLPAFPTDIKNT----SVTTVPNMSQLQTSVGIVPTQAIATGP- 343

Query: 327 AHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGK 386
             TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+ K
Sbjct: 344 --TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPK 401

Query: 387 SCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNP-SSLGV 445
           +CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQQ IL     G+ N   S+G 
Sbjct: 402 ACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGA 461

Query: 446 GQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMXXXXXXXXXXXXXXXXXXXXXGMRP 505
           GQQ+A +LS  + IDPSS++RAYAALGLPY +NQ                       MR 
Sbjct: 462 GQQNATSLSNPNPIDPSSMQRAYAALGLPY-MNQ-PQTQLQPQVPGQQPAQPPAHQQMRT 519

Query: 506 MSNMSASPMGVNGG---VGVQTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMPTA 559
           ++ +  +PM V  G      Q P+L+S+S L +++ + NP+M   S + ++ SL  +PTA
Sbjct: 520 LNALGNNPMSVPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTA 579

Query: 560 AQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDM 619
           A PS+TG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGDM
Sbjct: 580 APPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDM 639

Query: 620 YESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSXXXXXXXXXXX 679
           YESAN+R EYYHLLAEKIYKIQKELEEKRRTRL KQ +L N   + P S           
Sbjct: 640 YESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPAL-PASGAQPPVIPPAQ 698

Query: 680 XXXTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMA-----QPPIVPRQTPPLQ 734
                NGPLP P           + R+    G+N F  MS+      Q P+ PR   P+ 
Sbjct: 699 SVRPPNGPLPLP-----------VNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMN 747

Query: 735 HHGQLAQPGALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQ--GMN 776
           H  Q+    ++ P M   P RM QP N               Q QFLPQ QFPS    M+
Sbjct: 748 HSVQMNSMASV-PGMAISPSRMPQPPNMMGTHANNIMAQAPTQNQFLPQNQFPSSSGAMS 806

Query: 777 VTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALH 828
           V ++ +   + QA VSQ Q   ++ P  +P+     Q S + CP + Q  LH
Sbjct: 807 VNSVGMGQPAAQAGVSQGQEPGAALP--NPLNMLAPQASQLPCPPVTQSPLH 856




 Score = 67.0 bits (162), Expect = 4e-09
 Identities = 40/108 (37%), Positives = 48/108 (44%)

Query: 2269 MGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNXXXXXXXXXXXXXXXXXXXXXXX 2328
            +GSP QPNPMSPQQHML  Q Q+ HL GQQI  SLSN                       
Sbjct: 2304 IGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPS 2363

Query: 2329 XXXXXXXXXXXXXXXXXXXXXGLVAAQANPMEQGHFASPDQNSMLSQL 2376
                                 GL    A+ M+QGH  +P+Q++ML QL
Sbjct: 2364 PRIQPQPSPHHVSPQTGTPHPGLAVTMASSMDQGHLGNPEQSAMLPQL 2411




 Score = 50.4 bits (119), Expect = 4e-04
 Identities = 49/183 (26%), Positives = 69/183 (37%), Gaps = 29/183 (15%)

Query: 2010 MPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNXXXXXXXXXXXXXXXX 2069
            MPRP M   AQ       A   G     + P +  ++S  ALQ+                
Sbjct: 2036 MPRPVMSMQAQ-------AAVAGPRMPNVQPNR--SISPSALQDLLRTLKSPSSPQQQQQ 2086

Query: 2070 XXXXXHANPQLLAAFIKQRAAKYANSNXXXXXXXXXXXXXXXXXXXXXXXXXXXVHSNPA 2129
                  +NPQL+AAFIKQR AKY  +                            +H  P+
Sbjct: 2087 VLNILKSNPQLMAAFIKQRTAKYVANQ-------PGMQPQPGLQSQPGMQPQPGMHQQPS 2139

Query: 2130 MQNMNPMQAGVQRAGXXXXXXXXXXXXXMGGMSPQAQQMNM-------NHNTMPSQFRDI 2182
            +QN+N MQA                   MGG++PQ Q +N+       N   M  Q+R++
Sbjct: 2140 LQNLNAMQA------GVPRPGVPPPQPAMGGLNPQGQALNIMNPGHNPNMTNMNPQYREM 2193

Query: 2183 LRR 2185
            +RR
Sbjct: 2194 VRR 2196



>gi|28486616|ref|XP_283295.1| similar to E1A-associated protein p300 [Mus musculus]
 gi|29244384|ref|NP_808489.1| hypothetical protein A730011L11 [Mus musculus]
 gi|26335221|dbj|BAC31311.1| unnamed protein product [Mus musculus]
          Length = 714

 Score = 1060 bits (2741), Expect = 0.0
 Identities = 604/712 (84%), Positives = 623/712 (87%), Gaps = 1/712 (0%)

Query: 1   MAENVVEPGPPSAKRPKXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
           MAENVVEPGPPSAKRPK           DGTDFGSLFDLEHDLPDELINSTELGLTNGGD
Sbjct: 1   MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60

Query: 61  INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS 120
           I+QLQTSLG+VQDAASKHKQLSELLRSGSSPNLNMGVGGPGQ MASQAQQ+SPGL LINS
Sbjct: 61  ISQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQAQQNSPGLSLINS 120

Query: 121 MVKSPMTQAGLTSPNMGMGTSGPNQGPTQS-TGMMNSPVNQPAMGMNTGTNAGMNPGMLA 179
           MVKSPM Q GLTSPNMG+G+SGPNQGPTQS  GMMNSPVNQPAMGMNTG NAGMNPGMLA
Sbjct: 121 MVKSPMAQTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQPAMGMNTGMNAGMNPGMLA 180

Query: 180 AGNGQGIMPNQVMNGSIGAGRGRQDMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGP 239
           AGNGQGIMPNQVMNGSIGAGRGR +MQYPN GMG+AG+LLTEPLQQGSPQMGGQ GLRGP
Sbjct: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEPLQQGSPQMGGQPGLRGP 240

Query: 240 QPLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVXXXXX 299
           QPLKMGMMNNP+PYGSPYTQN GQQIGASGLGLQIQTKTVL NNLSPFAMDKKAV     
Sbjct: 241 QPLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVPGGGM 300

Query: 300 XXXXXXXXXXXXXXGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANG 359
                         GLVTPVA GMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANG
Sbjct: 301 PSMGQQPTPSVQQPGLVTPVAAGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANG 360

Query: 360 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 419
           EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN
Sbjct: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420

Query: 420 AGDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQ 479
           AGDKRNQQ ILTGAPVGLGNPSSLGVGQQS P+LSTVSQIDPSSIERAYAALGLPYQVNQ
Sbjct: 421 AGDKRNQQSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQ 480

Query: 480 MXXXXXXXXXXXXXXXXXXXXXGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINS 539
           +                     GMR ++NMSASPMGVNGGVGVQTP+LLSDSMLHS INS
Sbjct: 481 IPPQPQVQAKNQQSQPSGQSPQGMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS 540

Query: 540 QNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 599
           QNPMMSENA V SLGP+PTAAQPS+TGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA
Sbjct: 541 QNPMMSENAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 600

Query: 600 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 659
           LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP
Sbjct: 601 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660

Query: 660 NAAGMVPVSXXXXXXXXXXXXXXTSNGPLPDPSMIRGSVPNQMMPRITPQSG 711
           NA GM PV               T+NGP+PDPSMIRGSVPN MMPR+TPQ G
Sbjct: 661 NAPGMGPVPMNTGSNMGQQPTGMTTNGPVPDPSMIRGSVPNHMMPRMTPQPG 712



>gi|547239|gb|AAB31182.1| p300=transcription coactivator {N-terminal} [mice, Peptide Partial,
           688 aa]
          Length = 688

 Score = 1031 bits (2665), Expect = 0.0
 Identities = 576/688 (83%), Positives = 594/688 (86%), Gaps = 1/688 (0%)

Query: 1   MAENVVEPGPPSAKRPKXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
           MAENVVEPGPPSAKR K           DGTDFGSLFDLEHDLPDELINSTELGLTNGGD
Sbjct: 1   MAENVVEPGPPSAKRLKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60

Query: 61  INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS 120
            +QLQTSLG+VQDAASKHKQLSELLRSGSSPNLNMGVGGPGQ MASQA Q+SPGL LINS
Sbjct: 61  SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQACQNSPGLSLINS 120

Query: 121 MVKSPMTQAGLTSPNMGMGTSGPNQGPTQS-TGMMNSPVNQPAMGMNTGTNAGMNPGMLA 179
           MVKSPM   GLTSPNMG+G+SGPNQGPTQS  GMMNSPVNQPAMGMNTG NAGMNPGMLA
Sbjct: 121 MVKSPMACTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQPAMGMNTGMNAGMNPGMLA 180

Query: 180 AGNGQGIMPNQVMNGSIGAGRGRQDMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGP 239
           AGNGQGIMPNQVMNGSIGAGRGR +MQYPN GMG+AG+LLTEPLQQGSPQMGGQ GLRGP
Sbjct: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEPLQQGSPQMGGQPGLRGP 240

Query: 240 QPLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVXXXXX 299
           QPLKMGMMNNP+PYGSPYTQN GQQIGASGLGLQIQTKTVL NNLSPFAMDKKAV     
Sbjct: 241 QPLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVPGGGM 300

Query: 300 XXXXXXXXXXXXXXGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANG 359
                         GLVTPVA GMGSGAHTADPEKR +IQQQLVLLLHAHKCQRREQANG
Sbjct: 301 PSMGQQPTPSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANG 360

Query: 360 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 419
           EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN
Sbjct: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420

Query: 420 AGDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQ 479
           AGDKRNQ  ILTGAPVGLGNPSSLGVGQQS P+LSTVSQIDPSSIERAYAALGLPYQVNQ
Sbjct: 421 AGDKRNQCSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQ 480

Query: 480 MXXXXXXXXXXXXXXXXXXXXXGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINS 539
           +                     GMR ++NMSASPMGVNGGVGVQTP+LLSDSMLHS INS
Sbjct: 481 IPPQPQVQAKNQQSQPSGQSPQGMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS 540

Query: 540 QNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 599
           QNPMMS NA V SLGP+PTAAQPS+TGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA
Sbjct: 541 QNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 600

Query: 600 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 659
           LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP
Sbjct: 601 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660

Query: 660 NAAGMVPVSXXXXXXXXXXXXXXTSNGP 687
           NA GM PV               T+NGP
Sbjct: 661 NAPGMGPVPMNTGSNMGQQPTGMTTNGP 688



>gi|31204369|ref|XP_311133.1| ENSANGP00000004748 [Anopheles gambiae]
 gi|30178093|gb|EAA06516.2| ENSANGP00000004748 [Anopheles gambiae str. PEST]
          Length = 2572

 Score = 1016 bits (2626), Expect = 0.0
 Identities = 515/782 (65%), Positives = 599/782 (76%), Gaps = 20/782 (2%)

Query: 1045 KKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKR 1104
            KK  FKPEELR+AL+PTLE L  Q+PES+PFR PVDP  LGIPDYFDIV+ PMDLSTI++
Sbjct: 1423 KKCSFKPEELREALLPTLEKLVTQEPESIPFRMPVDPNSLGIPDYFDIVRQPMDLSTIRK 1482

Query: 1105 KLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCC 1164
            KL++GQYQ+P +YVDD+WLMF+NAWLYNRKTSRVY+YC+KLSEVFE EIDPVMQSLGYCC
Sbjct: 1483 KLESGQYQDPREYVDDVWLMFDNAWLYNRKTSRVYRYCTKLSEVFEMEIDPVMQSLGYCC 1542

Query: 1165 GRKLEFSPQTLCCYGKQLCTIPRDATYYSYQN--------RYHFCEKCFNEIQGESVSLG 1216
            GRK  F+PQ LCCYGKQLCTIPRDA YYSYQN        RY +C+KCFNEI G++V+LG
Sbjct: 1543 GRKYTFNPQVLCCYGKQLCTIPRDAKYYSYQNRSFGALSTRYTYCQKCFNEIPGDTVTLG 1602

Query: 1217 DDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCL 1276
            DDP Q QT I K+QF + KND L+ E FV+C +CGRK HQICVL+ E IWP GFVCD CL
Sbjct: 1603 DDPMQSQTQIKKDQFKEMKNDHLELEPFVDCLDCGRKQHQICVLYLESIWPGGFVCDACL 1662

Query: 1277 KKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVK 1336
            KK  + RK+NKF+AKRLP+++LGT++E RVN+FL+++    +GEV +RVV +SDK VEVK
Sbjct: 1663 KKKGQKRKDNKFNAKRLPTSKLGTYIETRVNNFLKKK-EAGAGEVHIRVVSSSDKMVEVK 1721

Query: 1337 PGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYIS 1396
            PGM++RFV++GEM   FPYR KALFAFEE+DGVD+CFFGMHVQEYGS+C  PN RRVYI+
Sbjct: 1722 PGMRSRFVENGEMLPEFPYRAKALFAFEEVDGVDVCFFGMHVQEYGSECAAPNTRRVYIA 1781

Query: 1397 YLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQK 1456
            YLDSVHFFRP+  RT+VYHEIL+GY++Y K+LGYT  HIWACPPSEGDDYIFHCHPP+Q+
Sbjct: 1782 YLDSVHFFRPRQYRTSVYHEILLGYMDYAKQLGYTMAHIWACPPSEGDDYIFHCHPPEQR 1841

Query: 1457 IPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVXXXX 1516
            IPKPKRLQEWYKKMLDK + ER + DYKDI KQA ED+L SA ELPYFEGDFWPNV    
Sbjct: 1842 IPKPKRLQEWYKKMLDKGMVERTIQDYKDILKQAMEDKLQSASELPYFEGDFWPNVLEES 1901

Query: 1517 XXXXXXXXXXXXXXXXXXXXSTDV--------TKGDXXXXXXXXXXXXXXXXXXLSRGNK 1568
                                +  +        T  D                    + NK
Sbjct: 1902 IKELDQEEEEKRKQAEREEAANAMIMSNDDSDTVADGKKKGQKKAKKSNKSKAAQRKSNK 1961

Query: 1569 KKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSXXXXXXXXXXXXXXXMDGRD 1628
            K      + NDLS K++ATMEKHKEVFFVIRL +  +A S               MDGRD
Sbjct: 1962 KTN--EQIGNDLSAKIFATMEKHKEVFFVIRLHSAQSAASLAPIQDPDPLINCDLMDGRD 2019

Query: 1629 AFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCED 1688
            AFLTLARDKH EFSSLRRAQ+ST+CML ELH Q QD+FVYTCN CK+HVETR+HCTVC+D
Sbjct: 2020 AFLTLARDKHFEFSSLRRAQFSTLCMLYELHNQGQDKFVYTCNNCKNHVETRYHCTVCDD 2079

Query: 1689 YDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQC 1748
            +DLCITC     H HKM+KLG  LDD S+      T +P ++R+ SIQRCIQSLVHACQC
Sbjct: 2080 FDLCITCKEKVGHQHKMDKLGFDLDDGSSPSDVKQT-NPQEARKQSIQRCIQSLVHACQC 2138

Query: 1749 RNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLN 1808
            R+ANC LPSCQKMKRVVQHTK CKRKT+GGCPICKQLIALCCYHAKHCQE KC VPFC N
Sbjct: 2139 RDANCRLPSCQKMKRVVQHTKHCKRKTHGGCPICKQLIALCCYHAKHCQEAKCLVPFCPN 2198

Query: 1809 IK 1810
            IK
Sbjct: 2199 IK 2200



>gi|7511830|pir||T13828 CREB-binding protein homolog - fruit fly (Drosophila melanogaster)
 gi|1916930|gb|AAB53050.1| CREB-binding protein homolog [Drosophila melanogaster]
          Length = 3190

 Score =  998 bits (2580), Expect = 0.0
 Identities = 513/791 (64%), Positives = 586/791 (74%), Gaps = 27/791 (3%)

Query: 1042 GQSKKKI-FKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLS 1100
            G  KKK  F PEELR AL+PTLE LYRQ+PES+PFR PVDPQ LGIPDYF+IVK PMDL 
Sbjct: 1689 GDKKKKCQFNPEELRTALLPTLEKLYRQEPESVPFRYPVDPQALGIPDYFEIVKKPMDLG 1748

Query: 1101 TIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSL 1160
            TI+  +  G+Y +PW+YVDD+WLMF+NAWLYN KTSRVY+YC+KLSEVFE EIDPVMQ+L
Sbjct: 1749 TIRTNIQNGKYSDPWEYVDDVWLMFDNAWLYNPKTSRVYRYCTKLSEVFEAEIDPVMQAL 1808

Query: 1161 GYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQ----------NRYHFCEKCFNEIQG 1210
            GYCCGRK  F+PQ LCCYGKQLCTIPRDA YYSYQ          NRY +C+KCFN+IQG
Sbjct: 1809 GYCCGRKYTFNPQVLCCYGKQLCTIPRDAKYYSYQNSLKEYGVASNRYTYCQKCFNDIQG 1868

Query: 1211 ESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGF 1270
            ++V+LGDDP Q QT I K+QF + KND L+ E FV C ECGRK HQICVL  + IWP GF
Sbjct: 1869 DTVTLGDDPLQSQTQIKKDQFKEMKNDHLELEPFVNCQECGRKQHQICVLWLDSIWPGGF 1928

Query: 1271 VCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASD 1330
            VCD CLKK    RKENKF+AKRLP+T+LG ++E RVN+FL+++    +GEV +RVV +SD
Sbjct: 1929 VCDNCLKKKNSKRKENKFNAKRLPTTKLGVYIETRVNNFLKKK-EAGAGEVHIRVVSSSD 1987

Query: 1331 KTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQ 1390
            K VEVKPGM+ RFV+ GEM   FPYR KALFAFEE+DG+D+CFFGMHVQEYGS+CP PN 
Sbjct: 1988 KCVEVKPGMRRRFVEQGEMMNEFPYRAKALFAFEEVDGIDVCFFGMHVQEYGSECPAPNT 2047

Query: 1391 RRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHC 1450
            RRVYI+YLDSVHFFRP+  RTAVYHEIL+GY++YVK+LGYT  HIWACPPSEGDDYIFHC
Sbjct: 2048 RRVYIAYLDSVHFFRPRQYRTAVYHEILLGYMDYVKQLGYTMAHIWACPPSEGDDYIFHC 2107

Query: 1451 HPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWP 1510
            HP DQKIPKPKRLQEWYKKMLDK + ERI+ DYKDI KQA ED+L SA ELPYFEGDFWP
Sbjct: 2108 HPTDQKIPKPKRLQEWYKKMLDKGMIERIIQDYKDILKQAMEDKLGSAAELPYFEGDFWP 2167

Query: 1511 NVXXXXXXXXXXXXXXXXXXXXXXXXSTDVT--------KGDXXXXXXXXXXXXXXXXXX 1562
            NV                        +                                 
Sbjct: 2168 NVLEESIKELDQEEEEKRKQAEAAEAAAAANLFSIEENEVSGDGKKKGQKKAKKSNKSKA 2227

Query: 1563 LSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSXXXXXXXXXXXXXX 1622
              R N KK       NDLS K+YATMEKHKEVFFVIRL +  +A S              
Sbjct: 2228 AQRKNSKKSNEHQSGNDLSTKIYATMEKHKEVFFVIRLHSAQSAASLAPIQDPDPLLTCD 2287

Query: 1623 XMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWH 1682
             MDGRDAFLTLARDKH EFSSLRRAQ+ST+ ML ELH Q QD+FVYTCN CK  VETR+H
Sbjct: 2288 LMDGRDAFLTLARDKHFEFSSLRRAQFSTLSMLYELHNQGQDKFVYTCNHCKTAVETRYH 2347

Query: 1683 CTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDES---NNQQAAATQSPGDSRRLSIQRCI 1739
            CTVC+D+DLCI C     H HKMEKLG  +DD S   +++QA    +P ++R+ SIQRCI
Sbjct: 2348 CTVCDDFDLCIVCKEKVGHQHKMEKLGFDIDDGSALADHKQA----NPQEARKQSIQRCI 2403

Query: 1740 QSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQEN 1799
            QSL HACQCR+ANC LPSCQKMK VVQHTK CKRK NGGCPICKQLIALCCYHAK+C+E 
Sbjct: 2404 QSLAHACQCRDANCRLPSCQKMKLVVQHTKNCKRKPNGGCPICKQLIALCCYHAKNCEEQ 2463

Query: 1800 KCPVPFCLNIK 1810
            KCPVPFC NIK
Sbjct: 2464 KCPVPFCPNIK 2474




 Score =  119 bits (299), Expect = 6e-25
 Identities = 71/137 (51%), Positives = 84/137 (61%)

Query: 515  GVNGGVGVQTPSLLSDSMLHSAINSQNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHED 574
            G +GG      S+L  +    + N+ NP  +        G              K W E 
Sbjct: 887  GASGGQVAAGSSVLMPADTTGSGNAGNPNQNAGGVAGGAGGGNGGNTGPPGDNEKDWRES 946

Query: 575  ITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLA 634
            +T DLRNHLVHKLVQAIFPT DP  ++D+RM NLV+YA KVE DMYE A +R+EYYHLLA
Sbjct: 947  VTADLRNHLVHKLVQAIFPTSDPTTMQDKRMHNLVSYAEKVEKDMYEMAKSRSEYYHLLA 1006

Query: 635  EKIYKIQKELEEKRRTR 651
            EKIYKIQKELEEKR  R
Sbjct: 1007 EKIYKIQKELEEKRLKR 1023



>gi|24640865|ref|NP_524642.2| nejire CG15319-PB [Drosophila melanogaster]
 gi|22833041|gb|AAF46516.2| CG15319-PB [Drosophila melanogaster]
          Length = 3276

 Score =  991 bits (2562), Expect = 0.0
 Identities = 514/791 (64%), Positives = 587/791 (74%), Gaps = 27/791 (3%)

Query: 1042 GQSKKKI-FKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLS 1100
            G  KKK  F PEELR AL+PTLE LYRQ+PES+PFR PVDPQ LGIPDYF+IVK PMDL 
Sbjct: 1689 GDKKKKCQFNPEELRTALLPTLEKLYRQEPESVPFRYPVDPQALGIPDYFEIVKKPMDLG 1748

Query: 1101 TIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSL 1160
            TI+  +  G+Y +PW+YVDD+WLMF+NAWLYNRKTSRVY+YC+KLSEVFE EIDPVMQ+L
Sbjct: 1749 TIRTNIQNGKYSDPWEYVDDVWLMFDNAWLYNRKTSRVYRYCTKLSEVFEAEIDPVMQAL 1808

Query: 1161 GYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQ----------NRYHFCEKCFNEIQG 1210
            GYCCGRK  F+PQ LCCYGKQLCTIPRDA YYSYQ          NRY +C+KCFN+IQG
Sbjct: 1809 GYCCGRKYTFNPQVLCCYGKQLCTIPRDAKYYSYQNSLKEYGVASNRYTYCQKCFNDIQG 1868

Query: 1211 ESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGF 1270
            ++V+LGDDP Q QT I K+QF + KND L+ E FV C ECGRK HQICVL  + IWP GF
Sbjct: 1869 DTVTLGDDPLQSQTQIKKDQFKEMKNDHLELEPFVNCQECGRKQHQICVLWLDSIWPGGF 1928

Query: 1271 VCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASD 1330
            VCD CLKK    RKENKF+AKRLP+T+LG ++E RVN+FL+++    +GEV +RVV +SD
Sbjct: 1929 VCDNCLKKKNSKRKENKFNAKRLPTTKLGVYIETRVNNFLKKK-EAGAGEVHIRVVSSSD 1987

Query: 1331 KTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQ 1390
            K VEVKPGM+ RFV+ GEM   FPYR KALFAFEE+DG+D+CFFGMHVQEYGS+CP PN 
Sbjct: 1988 KCVEVKPGMRRRFVEQGEMMNEFPYRAKALFAFEEVDGIDVCFFGMHVQEYGSECPAPNT 2047

Query: 1391 RRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHC 1450
            RRVYI+YLDSVHFFRP+  RTAVYHEIL+GY++YVK+LGYT  HIWACPPSEGDDYIFHC
Sbjct: 2048 RRVYIAYLDSVHFFRPRQYRTAVYHEILLGYMDYVKQLGYTMAHIWACPPSEGDDYIFHC 2107

Query: 1451 HPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWP 1510
            HP DQKIPKPKRLQEWYKKMLDK + ERI+ DYKDI KQA ED+L SA ELPYFEGDFWP
Sbjct: 2108 HPTDQKIPKPKRLQEWYKKMLDKGMIERIIQDYKDILKQAMEDKLGSAAELPYFEGDFWP 2167

Query: 1511 NVXXXXXXXXXXXXXXXXXXXXXXXXSTDVT--------KGDXXXXXXXXXXXXXXXXXX 1562
            NV                        +                                 
Sbjct: 2168 NVLEESIKELDQEEEEKRKQAEAAEAAAAANLFSIEENEVSGDGKKKGQKKAKKSNKSKA 2227

Query: 1563 LSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSXXXXXXXXXXXXXX 1622
              R N KK       NDLS K+YATMEKHKEVFFVIRL +  +A S              
Sbjct: 2228 AQRKNSKKSNEHQSGNDLSTKIYATMEKHKEVFFVIRLHSAQSAASLAPIQDPDPLLTCD 2287

Query: 1623 XMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWH 1682
             MDGRDAFLTLARDKH EFSSLRRAQ+ST+ ML ELH Q QD+FVYTCN CK  VETR+H
Sbjct: 2288 LMDGRDAFLTLARDKHFEFSSLRRAQFSTLSMLYELHNQGQDKFVYTCNHCKTAVETRYH 2347

Query: 1683 CTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDES---NNQQAAATQSPGDSRRLSIQRCI 1739
            CTVC+D+DLCI C     H HKMEKLG  +DD S   +++QA    +P ++R+ SIQRCI
Sbjct: 2348 CTVCDDFDLCIVCKEKVGHQHKMEKLGFDIDDGSALADHKQA----NPQEARKQSIQRCI 2403

Query: 1740 QSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQEN 1799
            QSL HACQCR+ANC LPSCQKMK VVQHTK CKRK NGGCPICKQLIALCCYHAK+C+E 
Sbjct: 2404 QSLAHACQCRDANCRLPSCQKMKLVVQHTKNCKRKPNGGCPICKQLIALCCYHAKNCEEQ 2463

Query: 1800 KCPVPFCLNIK 1810
            KCPVPFC NIK
Sbjct: 2464 KCPVPFCPNIK 2474




 Score =  119 bits (297), Expect = 1e-24
 Identities = 71/137 (51%), Positives = 84/137 (61%)

Query: 515  GVNGGVGVQTPSLLSDSMLHSAINSQNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHED 574
            G +GG      S+L  +    + N+ NP  +        G              K W E 
Sbjct: 887  GASGGQVAAGSSVLMPADTTGSGNAGNPNQNAGGVAGGAGGGNGGNTGPPGDNEKDWRES 946

Query: 575  ITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLA 634
            +T DLRNHLVHKLVQAIFPT DP  ++D+RM NLV+YA KVE DMYE A +R+EYYHLLA
Sbjct: 947  VTADLRNHLVHKLVQAIFPTSDPTTMQDKRMHNLVSYAEKVEKDMYEMAKSRSEYYHLLA 1006

Query: 635  EKIYKIQKELEEKRRTR 651
            EKIYKIQKELEEKR  R
Sbjct: 1007 EKIYKIQKELEEKRLKR 1023



>gi|21307831|gb|AAL54859.1| CREB-binding protein [Aplysia californica]
          Length = 2245

 Score =  943 bits (2438), Expect = 0.0
 Identities = 514/880 (58%), Positives = 612/880 (69%), Gaps = 39/880 (4%)

Query: 957  TSST------------EVNSQAIAEKQPSQEVKM-EAKMEVDQPEPADTQPEDISESKVE 1003
            TSST            +V +++  + +  QEV++ E KM+  + E ++ +PE   +S   
Sbjct: 879  TSSTTVSSMLNLPQKGDVKTESSTDVKVKQEVEVKEEKMDTGKSE-SEVKPE--PDSIKA 935

Query: 1004 DCKMXXXXXXXXXXXXXXXIKEEEDXXXXXXXXXXXXXGQSK-KKIFKPEELRQALMPTL 1062
            + +                I+E+                + + KK+F  +ELRQALMPTL
Sbjct: 936  ENETSSPKLDNLDESSQASIEEKPASVGDASNNSAASTPKPRCKKVFDKDELRQALMPTL 995

Query: 1063 EALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIW 1122
            E L++QDPESLPFRQPVDP +L IPDYFDIVK PMDLSTI+RKLD+G Y +PW+YVDD+ 
Sbjct: 996  EKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPMDLSTIRRKLDSGLYSDPWEYVDDVC 1055

Query: 1123 LMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQL 1182
            LMF+NAWLYNRKTSRVYKY SKLSEVFE EID VMQSLGYCCG K  F PQ LCCYGKQL
Sbjct: 1056 LMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVMQSLGYCCGHKYVFCPQVLCCYGKQL 1115

Query: 1183 CTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPE 1242
            CTIPRD+ YYSYQNRY +CEKCFNEIQ + V L +DP+QP T I K+QF + KND LD E
Sbjct: 1116 CTIPRDSMYYSYQNRYVYCEKCFNEIQTDEVELSEDPTQPMTKIRKDQFDRVKNDQLDYE 1175

Query: 1243 LFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFL 1302
             F++C ECGR+ HQIC L  E IW  G+ CD CLK     RKENKF++K+LP+T+LGT+L
Sbjct: 1176 PFIDCQECGRRWHQICALWFESIWREGWSCDSCLKAKGVKRKENKFTSKKLPTTKLGTYL 1235

Query: 1303 ENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFA 1362
            ENRVN+FLR+++   +GEVT+RV+ + DK  EVKP MK RF    +M +S+PYR KA+FA
Sbjct: 1236 ENRVNNFLRKKD-SGAGEVTIRVLSSYDKMTEVKPLMKKRF--GNDMEDSYPYRAKAMFA 1292

Query: 1363 FEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYL 1422
            FEEIDGVD+CFFGMHVQEYGS CP PN RRVYISYLDSVHFF+P+ LRTAVYHEILIGYL
Sbjct: 1293 FEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISYLDSVHFFKPRHLRTAVYHEILIGYL 1352

Query: 1423 EYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHD 1482
            EY K LGYTT HIWACPPSEGDDYIFHCHPP+QKIPKPKRLQEWYKKMLDKA+ +R+V D
Sbjct: 1353 EYAKTLGYTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVD 1412

Query: 1483 YKDIFKQATEDRLTSAKELPYFEGDFWPNV------------XXXXXXXXXXXXXXXXXX 1530
            YKDIFK A +  ++SAK+L YFEGDFWPNV                              
Sbjct: 1413 YKDIFKDAIDSGISSAKDLAYFEGDFWPNVIEESIKELDQEEEEKRRREEAEAAAAEAEA 1472

Query: 1531 XXXXXXSTDVTKGDXXXXXXXXXXXXXXXXXXLSRG----NKKKPGMPNVSNDLSQKLYA 1586
                  +TD    D                   S+G    N +K  +P  +NDL+ KLY 
Sbjct: 1473 QDTVEETTDAVCSDVAGTKKGEKKGQRNKKANKSKGSARKNNRKTNLPQGTNDLTAKLYN 1532

Query: 1587 TMEKHKEVFFVIRLIAGPAANSXXXXXXXXXXXXXXXMDGRDAFLTLARDKHLEFSSLRR 1646
             MEKHKEVFFVIRL     A S               MDGRDAFLT AR+KH EFSSLRR
Sbjct: 1533 HMEKHKEVFFVIRLHNQQIAASLPPITEPDPAMSCELMDGRDAFLTTAREKHYEFSSLRR 1592

Query: 1647 AQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKME 1706
            A+ S+M +L ELH Q +D FVYTCN CK  VETR+HC+ C+D+DLC+ CYN + H HKM 
Sbjct: 1593 AKLSSMALLYELHNQGKDAFVYTCNSCKAAVETRYHCSTCDDFDLCVPCYNKEGHHHKMT 1652

Query: 1707 KLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQ 1766
            KLGLGLDD +++ +    ++P +SRR SIQRCI SLVHACQCRNANC + +C KMKRVV 
Sbjct: 1653 KLGLGLDDIASSDK---EENPQESRRKSIQRCISSLVHACQCRNANCRMNACHKMKRVVG 1709

Query: 1767 HTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFC 1806
            HT  C+RKTN GCPICKQLIALCCYHAKHC ENKC VPFC
Sbjct: 1710 HTMSCRRKTNNGCPICKQLIALCCYHAKHCVENKCQVPFC 1749




 Score = 40.8 bits (94), Expect = 0.37
 Identities = 33/102 (32%), Positives = 44/102 (43%), Gaps = 14/102 (13%)

Query: 1716 SNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNAN-----CSLPSCQKMKRVVQHTKG 1770
            S  +QAA    P  S+ +  Q  +    H CQ R  N     C LP C+ MK V+ H   
Sbjct: 271  SGPRQAAG--EPDKSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTT 328

Query: 1771 CKRKTN---GGCPICKQLIALCCYHAKHCQENKCPVPFCLNI 1809
            C +  +     C   +Q+I     H K+C    CPV F L I
Sbjct: 329  CNKGKSCEVAHCASSRQIIT----HWKNCLRQDCPVCFALKI 366




 Score = 40.4 bits (93), Expect = 0.48
 Identities = 88/304 (28%), Positives = 116/304 (38%), Gaps = 79/304 (25%)

Query: 9   GPPSAKRPKXXXXXXXXXXXDGT-DFGSL-FD-LEHDLPDELINSTELGLT-NGGDINQL 64
           GPP+ K+P+           +   +FG+L FD + ++LPD+L      GL    GD    
Sbjct: 7   GPPANKKPRIGSPSLNTPSDNNEFNFGNLNFDGIVNELPDDLD-----GLQGTSGDGQTP 61

Query: 65  QTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSP--GLGLINSMV 122
           Q S    QD  S    LS+LL S S+PN    +  P           SP  G  +   M 
Sbjct: 62  QGS----QD-TSMGGSLSQLL-SRSTPNSQTSLPLPVNSAGGIQTSRSPGMGAMMNMGMG 115

Query: 123 KSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGTNA----------G 172
           K+PM+          +  +  N+  T S   MN  +   A    +GTNA          G
Sbjct: 116 KNPMSN--------NLAATLANKAATSSHMNMNDALVSSASFTISGTNAGPMGGVTNTMG 167

Query: 173 MNPGMLAAGNGQGI-----------MPNQVMN------GSIGAGRGRQ--------DMQY 207
           MNP M   GN Q I           MPNQ+MN      G++G  R  Q         MQ 
Sbjct: 168 MNPTM---GNPQMIGSVGSLNMNQQMPNQMMNGPTSFPGNMGQMRAMQGNNVNPSTSMQV 224

Query: 208 PNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQPLKMGMMNNPNPYGSPYTQNPGQQIGA 267
           P  GM  +          G PQM G  G+ G   + M       P   P    PGQ  G+
Sbjct: 225 PQTGMMQS---------PGMPQMQGHQGMPGHPNMNM-------PQNPPQNIRPGQPTGS 268

Query: 268 SGLG 271
              G
Sbjct: 269 GTSG 272



>gi|2133462|pir||S60123 hypothetical protein R10E11.1 - Caenorhabditis elegans
          Length = 2027

 Score =  731 bits (1886), Expect = 0.0
 Identities = 385/778 (49%), Positives = 494/778 (63%), Gaps = 23/778 (2%)

Query: 1048 IFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLD 1107
            +F  E+L + L+P  E L + + ++ PFR PVD +LL IPDY +I+K PMDL T+ +KL 
Sbjct: 863  VFSQEDLIKFLLPVWEKLDKSE-DAAPFRVPVDAKLLNIPDYHEIIKRPMDLETVHKKLY 921

Query: 1108 TGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRK 1167
             GQYQ   Q+ DDIWLM +NAWLYNRK S+VYKY  KLSE+F  E+DPVM+S+GYCC +K
Sbjct: 922  AGQYQNAGQFCDDIWLMLDNAWLYNRKNSKVYKYGLKLSEMFVSEMDPVMKSMGYCCAKK 981

Query: 1168 LEFSPQTLCCYGKQLCTIPRDATYYSYQN-----------RYHFCEKCFNEIQGESVSLG 1216
            L F+P +L CYG  +CTI R+  Y+ ++            RY +C+KCF+ +  E +SL 
Sbjct: 982  LAFTPLSLFCYGAAMCTIAREQQYWVFEQSSTQYNVTVTERYTYCQKCFDALPPEGISLS 1041

Query: 1217 DDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCL 1276
            ++P+       K  F+++KN  +D E F  C  C RK H+IC LH + ++P GF+C+ C 
Sbjct: 1042 ENPNDRNNMAPKTSFTEQKNSVIDYEPFERCKYCMRKWHRICALHDKKVYPEGFICECCR 1101

Query: 1277 KKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGE--VTVRVVHASDKTVE 1334
                  + +NK+ A +LP  +L TFLE+RVN F+++Q   E+ +  V +R +   DK  E
Sbjct: 1102 TAKKYQKPDNKYLASKLPHNKLSTFLEDRVNGFIKKQLQAEAHKYPVIIRTLCVQDKEAE 1161

Query: 1335 VKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVY 1394
            VK  MK ++V+S +  E FPYRTKA+FAFE IDGV++CFFG+HVQEYGS CP PN RRVY
Sbjct: 1162 VKAQMKQKYVESNQFPEKFPYRTKAVFAFEIIDGVEVCFFGLHVQEYGSACPAPNARRVY 1221

Query: 1395 ISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPD 1454
            I+YLDSVHFF+P+ LRT VYHE+L+GYL+Y K LGYT  HIWACPPSEGDDYIFHCHPP+
Sbjct: 1222 IAYLDSVHFFQPRELRTDVYHELLLGYLDYAKMLGYTMAHIWACPPSEGDDYIFHCHPPE 1281

Query: 1455 QKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVXX 1514
            QKIPKPKRLQ+WYKKML+K V E  V ++KDI+KQA +D LT+  +LPYFEGDFWPNV  
Sbjct: 1282 QKIPKPKRLQDWYKKMLEKGVQEGSVVEFKDIYKQARDDNLTTPTQLPYFEGDFWPNVIE 1341

Query: 1515 XXXXXXXXXXXXXXXXXXXXXXSTDVTKGDXXXXXXXXXXXXXXXXXXLSRGNKKKPGMP 1574
                                                             +    KK    
Sbjct: 1342 DCIREASNEEAQRKVKEDDDDGEDADGGLGGGDSGKKKSSKNKKNNLKKNAKMNKKKAGS 1401

Query: 1575 NVSNDLSQKLYATMEKHKEVFFVIRLIA--GPAANSXXXXXXXXXXXXXXXMDGRDAFLT 1632
               N+++ KLY+  EKHKEVFF IRL++     A                 MDGRD FLT
Sbjct: 1402 ITGNEVADKLYSQFEKHKEVFFTIRLVSLQNEPAVLAKPISDPDGLMQSDMMDGRDTFLT 1461

Query: 1633 LARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLC 1692
             AR++H EFSSLRRA++ST+C+   LH        YTCN+C       WHC  C+D+DLC
Sbjct: 1462 KAREEHWEFSSLRRAKYSTLCLAYSLHETDSKGMEYTCNKCSS--PAVWHCQSCDDFDLC 1519

Query: 1693 ITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNAN 1752
              C  T  H H+MEK+   +        AA     G +R  SIQRCI SLVHACQCR+AN
Sbjct: 1520 DGCKPTTQHPHEMEKIKSLIGGGEAGDSAA-----GGTRYESIQRCIASLVHACQCRDAN 1574

Query: 1753 CSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIK 1810
            C   SC KMKRVVQHTK CK++ NG CP+CKQLIALCCYHAKHC  + C VPFC+NI+
Sbjct: 1575 CRRMSCHKMKRVVQHTKMCKKRINGTCPVCKQLIALCCYHAKHCTRDACTVPFCMNIR 1632




 Score = 93.6 bits (231), Expect = 5e-17
 Identities = 119/366 (32%), Positives = 141/366 (38%), Gaps = 61/366 (16%)

Query: 95  MGVGGPGQVMASQAQQSS--------PGLGLINSMVKSPMTQAGLTSPNMGM-------G 139
           M  G PG     Q QQ          PG+     M + P  Q G      GM        
Sbjct: 168 MRPGQPGMFQGDQQQQMMMGAQGQQFPGM-----MHRYPYAQGGPPPGAQGMPQGYPGVS 222

Query: 140 TSGPNQGPTQSTGMMNSPVNQPAMGMNTGTNAGMNPGMLAAGNGQGIMPNQVMNGSIGAG 199
             GP  G     G M +     +  M T    G+ P   A           + +G  G  
Sbjct: 223 RGGPTPGQPMGRGAMMNGAMPRSGPMPTQGRPGIPPNQQAMMQPMMTDRQFMQHGQYGQQ 282

Query: 200 RGRQDMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQPLKMGMMNNPNP---YGSP 256
           R     QY  PG           + QG         +RGP   +M MM+N +P   +G P
Sbjct: 283 RPEFMQQYGRPGGYPM-------MHQGMMMDSNGQPIRGPN--QMMMMSNGHPGMSHGPP 333

Query: 257 YTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVXXXXXXXXXXXXXXXXXXXGLV 316
             Q PG              +       +  A  + A                    G  
Sbjct: 334 NGQ-PGP--------QAAAAQHAAQQQAAAQAQAQAAAQQQQQQQREQEAAAAAQRNGAG 384

Query: 317 TPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEV---------RQCNLP 367
                G    A   DPEKRKLIQQQLVLLLHAHKC +RE+ N +            C LP
Sbjct: 385 RATTPGSSMLATHQDPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLP 444

Query: 368 HCRTMKNVLNHMTHC-----------QSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLP 416
           HC TMK VL HMT C           Q+ K C VAHCASSRQII+HWKNC+R DCPVC P
Sbjct: 445 HCSTMKEVLTHMTSCNVGRLCHSDTTQTTKKCSVAHCASSRQIIAHWKNCSREDCPVCKP 504

Query: 417 LKNAGD 422
           LK   D
Sbjct: 505 LKRIQD 510



>gi|17552708|ref|NP_499161.1| CBP/p300 homolog (cbp-1) [Caenorhabditis elegans]
 gi|14530537|emb|CAA82353.2| C. elegans CBP-1 protein (corresponding sequence R10E11.1a)
            [Caenorhabditis elegans]
          Length = 2045

 Score =  729 bits (1883), Expect = 0.0
 Identities = 385/778 (49%), Positives = 494/778 (63%), Gaps = 23/778 (2%)

Query: 1048 IFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLD 1107
            +F  E+L + L+P  E L + + ++ PFR PVD +LL IPDY +I+K PMDL T+ +KL 
Sbjct: 852  VFSQEDLIKFLLPVWEKLDKSE-DAAPFRVPVDAKLLNIPDYHEIIKRPMDLETVHKKLY 910

Query: 1108 TGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRK 1167
             GQYQ   Q+ DDIWLM +NAWLYNRK S+VYKY  KLSE+F  E+DPVM+S+GYCC +K
Sbjct: 911  AGQYQNAGQFCDDIWLMLDNAWLYNRKNSKVYKYGLKLSEMFVSEMDPVMKSMGYCCAKK 970

Query: 1168 LEFSPQTLCCYGKQLCTIPRDATYYSYQN-----------RYHFCEKCFNEIQGESVSLG 1216
            L F+P +L CYG  +CTI R+  Y+ ++            RY +C+KCF+ +  E +SL 
Sbjct: 971  LAFTPLSLFCYGAAMCTIAREQQYWVFEQSSTQYNVTVTERYTYCQKCFDALPPEGISLS 1030

Query: 1217 DDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCL 1276
            ++P+       K  F+++KN  +D E F  C  C RK H+IC LH + ++P GF+C+ C 
Sbjct: 1031 ENPNDRNNMAPKTSFTEQKNSVIDYEPFERCKYCMRKWHRICALHDKKVYPEGFICECCR 1090

Query: 1277 KKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGE--VTVRVVHASDKTVE 1334
                  + +NK+ A +LP  +L TFLE+RVN F+++Q   E+ +  V +R +   DK  E
Sbjct: 1091 TAKKYQKPDNKYLASKLPHNKLSTFLEDRVNGFIKKQLQAEAHKYPVIIRTLCVQDKEAE 1150

Query: 1335 VKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVY 1394
            VK  MK ++V+S +  E FPYRTKA+FAFE IDGV++CFFG+HVQEYGS CP PN RRVY
Sbjct: 1151 VKAQMKQKYVESNQFPEKFPYRTKAVFAFEIIDGVEVCFFGLHVQEYGSACPAPNARRVY 1210

Query: 1395 ISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPD 1454
            I+YLDSVHFF+P+ LRT VYHE+L+GYL+Y K LGYT  HIWACPPSEGDDYIFHCHPP+
Sbjct: 1211 IAYLDSVHFFQPRELRTDVYHELLLGYLDYAKMLGYTMAHIWACPPSEGDDYIFHCHPPE 1270

Query: 1455 QKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVXX 1514
            QKIPKPKRLQ+WYKKML+K V E  V ++KDI+KQA +D LT+  +LPYFEGDFWPNV  
Sbjct: 1271 QKIPKPKRLQDWYKKMLEKGVQEGSVVEFKDIYKQARDDNLTTPTQLPYFEGDFWPNVIE 1330

Query: 1515 XXXXXXXXXXXXXXXXXXXXXXSTDVTKGDXXXXXXXXXXXXXXXXXXLSRGNKKKPGMP 1574
                                                             +    KK    
Sbjct: 1331 DCIREASNEEAQRKVKEDDDDGEDADGGLGGGDSGKKKSSKNKKNNLKKNAKMNKKKAGS 1390

Query: 1575 NVSNDLSQKLYATMEKHKEVFFVIRLIA--GPAANSXXXXXXXXXXXXXXXMDGRDAFLT 1632
               N+++ KLY+  EKHKEVFF IRL++     A                 MDGRD FLT
Sbjct: 1391 ITGNEVADKLYSQFEKHKEVFFTIRLVSLQNEPAVLAKPISDPDGLMQSDMMDGRDTFLT 1450

Query: 1633 LARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLC 1692
             AR++H EFSSLRRA++ST+C+   LH        YTCN+C       WHC  C+D+DLC
Sbjct: 1451 KAREEHWEFSSLRRAKYSTLCLAYSLHETDSKGMEYTCNKCSS--PAVWHCQSCDDFDLC 1508

Query: 1693 ITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNAN 1752
              C  T  H H+MEK+   +        AA     G +R  SIQRCI SLVHACQCR+AN
Sbjct: 1509 DGCKPTTQHPHEMEKIKSLIGGGEAGDSAA-----GGTRYESIQRCIASLVHACQCRDAN 1563

Query: 1753 CSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIK 1810
            C   SC KMKRVVQHTK CK++ NG CP+CKQLIALCCYHAKHC  + C VPFC+NI+
Sbjct: 1564 CRRMSCHKMKRVVQHTKMCKKRINGTCPVCKQLIALCCYHAKHCTRDACTVPFCMNIR 1621




 Score =  122 bits (307), Expect = 6e-26
 Identities = 60/101 (59%), Positives = 78/101 (77%)

Query: 554 GPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYAR 613
           G +P    P      K+WH  +T+DLRNHLV KLV+AIFP P+  A+ D R+++L+AYAR
Sbjct: 570 GEIPNLPPPDMPDCTKEWHHQVTKDLRNHLVGKLVKAIFPEPNQEAMNDNRLKDLIAYAR 629

Query: 614 KVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQK 654
           KVE +M+ESAN+R EYYHLLAEKIYKIQKEL+EK+ +RL +
Sbjct: 630 KVEKEMFESANDREEYYHLLAEKIYKIQKELQEKKNSRLNQ 670




 Score = 98.2 bits (243), Expect = 2e-18
 Identities = 117/355 (32%), Positives = 139/355 (39%), Gaps = 50/355 (14%)

Query: 95  MGVGGPGQVMASQAQQSS--------PGLGLINSMVKSPMTQAGLTSPNMGM-------G 139
           M  G PG     Q QQ          PG+     M + P  Q G      GM        
Sbjct: 168 MRPGQPGMFQGDQQQQMMMGAQGQQFPGM-----MHRYPYAQGGPPPGAQGMPQGYPGVS 222

Query: 140 TSGPNQGPTQSTGMMNSPVNQPAMGMNTGTNAGMNPGMLAAGNGQGIMPNQVMNGSIGAG 199
             GP  G     G M +     +  M T    G+ P   A           + +G  G  
Sbjct: 223 RGGPTPGQPMGRGAMMNGAMPRSGPMPTQGRPGIPPNQQAMMQPMMTDRQFMQHGQYGQQ 282

Query: 200 RGRQDMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQPLKMGMMNNPNP---YGSP 256
           R     QY  PG           + QG         +RGP   +M MM+N +P   +G P
Sbjct: 283 RPEFMQQYGRPGGYPM-------MHQGMMMDSNGQPIRGPN--QMMMMSNGHPGMSHGPP 333

Query: 257 YTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVXXXXXXXXXXXXXXXXXXXGLV 316
             Q PG              +       +  A  + A                    G  
Sbjct: 334 NGQ-PGP--------QAAAAQHAAQQQAAAQAQAQAAAQQQQQQQREQEAAAAAQRNGAG 384

Query: 317 TPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEV---------RQCNLP 367
                G    A   DPEKRKLIQQQLVLLLHAHKC +RE+ N +            C LP
Sbjct: 385 RATTPGSSMLATHQDPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLP 444

Query: 368 HCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGD 422
           HC TMK VL HMT C  G+ C  AHCASSRQII+HWKNC+R DCPVC PLK   D
Sbjct: 445 HCSTMKEVLTHMTSCNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCKPLKRIQD 499



>gi|17552710|ref|NP_499160.1| CBP/p300 homolog (cbp-1) [Caenorhabditis elegans]
 gi|20455476|sp|P34545|CBP1_CAEEL Protein cbp-1
 gi|25299632|pir||G88564 protein R10E11.1 [imported] - Caenorhabditis elegans
 gi|17645979|emb|CAD18875.1| C. elegans CBP-1 protein (corresponding sequence R10E11.1b)
            [Caenorhabditis elegans]
          Length = 2056

 Score =  729 bits (1883), Expect = 0.0
 Identities = 385/778 (49%), Positives = 494/778 (63%), Gaps = 23/778 (2%)

Query: 1048 IFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLD 1107
            +F  E+L + L+P  E L + + ++ PFR PVD +LL IPDY +I+K PMDL T+ +KL 
Sbjct: 863  VFSQEDLIKFLLPVWEKLDKSE-DAAPFRVPVDAKLLNIPDYHEIIKRPMDLETVHKKLY 921

Query: 1108 TGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRK 1167
             GQYQ   Q+ DDIWLM +NAWLYNRK S+VYKY  KLSE+F  E+DPVM+S+GYCC +K
Sbjct: 922  AGQYQNAGQFCDDIWLMLDNAWLYNRKNSKVYKYGLKLSEMFVSEMDPVMKSMGYCCAKK 981

Query: 1168 LEFSPQTLCCYGKQLCTIPRDATYYSYQN-----------RYHFCEKCFNEIQGESVSLG 1216
            L F+P +L CYG  +CTI R+  Y+ ++            RY +C+KCF+ +  E +SL 
Sbjct: 982  LAFTPLSLFCYGAAMCTIAREQQYWVFEQSSTQYNVTVTERYTYCQKCFDALPPEGISLS 1041

Query: 1217 DDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCL 1276
            ++P+       K  F+++KN  +D E F  C  C RK H+IC LH + ++P GF+C+ C 
Sbjct: 1042 ENPNDRNNMAPKTSFTEQKNSVIDYEPFERCKYCMRKWHRICALHDKKVYPEGFICECCR 1101

Query: 1277 KKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGE--VTVRVVHASDKTVE 1334
                  + +NK+ A +LP  +L TFLE+RVN F+++Q   E+ +  V +R +   DK  E
Sbjct: 1102 TAKKYQKPDNKYLASKLPHNKLSTFLEDRVNGFIKKQLQAEAHKYPVIIRTLCVQDKEAE 1161

Query: 1335 VKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVY 1394
            VK  MK ++V+S +  E FPYRTKA+FAFE IDGV++CFFG+HVQEYGS CP PN RRVY
Sbjct: 1162 VKAQMKQKYVESNQFPEKFPYRTKAVFAFEIIDGVEVCFFGLHVQEYGSACPAPNARRVY 1221

Query: 1395 ISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPD 1454
            I+YLDSVHFF+P+ LRT VYHE+L+GYL+Y K LGYT  HIWACPPSEGDDYIFHCHPP+
Sbjct: 1222 IAYLDSVHFFQPRELRTDVYHELLLGYLDYAKMLGYTMAHIWACPPSEGDDYIFHCHPPE 1281

Query: 1455 QKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVXX 1514
            QKIPKPKRLQ+WYKKML+K V E  V ++KDI+KQA +D LT+  +LPYFEGDFWPNV  
Sbjct: 1282 QKIPKPKRLQDWYKKMLEKGVQEGSVVEFKDIYKQARDDNLTTPTQLPYFEGDFWPNVIE 1341

Query: 1515 XXXXXXXXXXXXXXXXXXXXXXSTDVTKGDXXXXXXXXXXXXXXXXXXLSRGNKKKPGMP 1574
                                                             +    KK    
Sbjct: 1342 DCIREASNEEAQRKVKEDDDDGEDADGGLGGGDSGKKKSSKNKKNNLKKNAKMNKKKAGS 1401

Query: 1575 NVSNDLSQKLYATMEKHKEVFFVIRLIA--GPAANSXXXXXXXXXXXXXXXMDGRDAFLT 1632
               N+++ KLY+  EKHKEVFF IRL++     A                 MDGRD FLT
Sbjct: 1402 ITGNEVADKLYSQFEKHKEVFFTIRLVSLQNEPAVLAKPISDPDGLMQSDMMDGRDTFLT 1461

Query: 1633 LARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLC 1692
             AR++H EFSSLRRA++ST+C+   LH        YTCN+C       WHC  C+D+DLC
Sbjct: 1462 KAREEHWEFSSLRRAKYSTLCLAYSLHETDSKGMEYTCNKCSS--PAVWHCQSCDDFDLC 1519

Query: 1693 ITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNAN 1752
              C  T  H H+MEK+   +        AA     G +R  SIQRCI SLVHACQCR+AN
Sbjct: 1520 DGCKPTTQHPHEMEKIKSLIGGGEAGDSAA-----GGTRYESIQRCIASLVHACQCRDAN 1574

Query: 1753 CSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIK 1810
            C   SC KMKRVVQHTK CK++ NG CP+CKQLIALCCYHAKHC  + C VPFC+NI+
Sbjct: 1575 CRRMSCHKMKRVVQHTKMCKKRINGTCPVCKQLIALCCYHAKHCTRDACTVPFCMNIR 1632




 Score = 93.6 bits (231), Expect = 4e-17
 Identities = 119/366 (32%), Positives = 141/366 (38%), Gaps = 61/366 (16%)

Query: 95  MGVGGPGQVMASQAQQSS--------PGLGLINSMVKSPMTQAGLTSPNMGM-------G 139
           M  G PG     Q QQ          PG+     M + P  Q G      GM        
Sbjct: 168 MRPGQPGMFQGDQQQQMMMGAQGQQFPGM-----MHRYPYAQGGPPPGAQGMPQGYPGVS 222

Query: 140 TSGPNQGPTQSTGMMNSPVNQPAMGMNTGTNAGMNPGMLAAGNGQGIMPNQVMNGSIGAG 199
             GP  G     G M +     +  M T    G+ P   A           + +G  G  
Sbjct: 223 RGGPTPGQPMGRGAMMNGAMPRSGPMPTQGRPGIPPNQQAMMQPMMTDRQFMQHGQYGQQ 282

Query: 200 RGRQDMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQPLKMGMMNNPNP---YGSP 256
           R     QY  PG           + QG         +RGP   +M MM+N +P   +G P
Sbjct: 283 RPEFMQQYGRPGGYPM-------MHQGMMMDSNGQPIRGPN--QMMMMSNGHPGMSHGPP 333

Query: 257 YTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVXXXXXXXXXXXXXXXXXXXGLV 316
             Q PG              +       +  A  + A                    G  
Sbjct: 334 NGQ-PGP--------QAAAAQHAAQQQAAAQAQAQAAAQQQQQQQREQEAAAAAQRNGAG 384

Query: 317 TPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEV---------RQCNLP 367
                G    A   DPEKRKLIQQQLVLLLHAHKC +RE+ N +            C LP
Sbjct: 385 RATTPGSSMLATHQDPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLP 444

Query: 368 HCRTMKNVLNHMTHC-----------QSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLP 416
           HC TMK VL HMT C           Q+ K C VAHCASSRQII+HWKNC+R DCPVC P
Sbjct: 445 HCSTMKEVLTHMTSCNVGRLCHSDTTQTTKKCSVAHCASSRQIIAHWKNCSREDCPVCKP 504

Query: 417 LKNAGD 422
           LK   D
Sbjct: 505 LKRIQD 510



>gi|27881767|gb|AAH44677.1| Similar to CREB binding protein (Rubinstein-Taybi syndrome)
           [Xenopus laevis]
          Length = 1047

 Score =  508 bits (1308), Expect = e-142
 Identities = 397/881 (45%), Positives = 505/881 (57%), Gaps = 76/881 (8%)

Query: 1   MAENVVEPGPPSAKRPKXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
           MAEN+++ GPP+ KRPK           D TDF S FDLE+DLPDELI        NGG+
Sbjct: 1   MAENLLD-GPPNRKRPK-LSSPGFSASTDSTDF-SFFDLENDLPDELI-------PNGGE 50

Query: 61  INQLQTSLGMVQDAASKHKQLSELLRSGSSP-NLNMGVGGPGQVMASQAQQS----SPGL 115
           ++ L T   + QDAAS+++QLS+LLR G++     MG G  G  +           SPGL
Sbjct: 51  LSILGTGGSLGQDAASQNRQLSDLLRGGNAGLGAAMGRGRSGSPVQQGLGSQGQQHSPGL 110

Query: 116 GLINSMVKSPMTQA-GLTSP---NMGMGTSGPNQGPTQSTGMMN------SPVNQP-AMG 164
           G + S+ KSP+ Q   +TSP       GT GP+   +Q+   ++      +P   P  + 
Sbjct: 111 GNLGSLNKSPLNQGLSVTSPAGLTKTTGTPGPSVPASQAQKQVSMVAGSTAPSQVPTGLC 170

Query: 165 MNTGTNAGMNPGMLAAGNGQGIMPN------QVMNGSIGAG-RGR-QDMQYPNPGMGS-A 215
           MN+  N G +  +L + +G  +M        QV+NGS+G G RGR   +QY +P M +  
Sbjct: 171 MNSNFNQG-HQTLLNSNSGHTLMSQAQPAQGQVLNGSLGVGSRGRGTALQYNSPAMQTNP 229

Query: 216 GNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQIGASGLGL 272
           G++L E L QG+  M    G+   Q     KMG+  N +P+G  + Q  GQQI A G+  
Sbjct: 230 GSVLAETLTQGTATMPTHAGMTTAQTGAMNKMGLPGNTSPFGQTFNQAAGQQIRAQGVSP 289

Query: 273 QIQTKTVLSNNLSPFAMDKKAVXXXXXXXXXXXXXXXXXXXGLVTPVAQGMGSGAHTADP 332
           Q+  K  ++N+L PF  D K                        +P    MG+G  TADP
Sbjct: 290 QLPAKPAMANSLPPFPSDIKNAPVANLPNMSPLQAQVQQVGIGTSP---SMGTGP-TADP 345

Query: 333 EKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAH 392
           EKRKLIQQQLVLLLHAHKCQRREQANGE+R C+LPHCRTMKNVLNHMTHCQ+GK+CQVAH
Sbjct: 346 EKRKLIQQQLVLLLHAHKCQRREQANGEMRDCSLPHCRTMKNVLNHMTHCQAGKACQVAH 405

Query: 393 CASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNPSSLGVGQQSAPN 452
           CASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQ   ++ A        + G GQQ+AP+
Sbjct: 406 CASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQNLPVSLASGVQSPIGTTGGGQQTAPS 465

Query: 453 LSTVSQIDPSSIERAYAALGLPYQVNQMXXXXXXXXXXXXXXXXXXXXXGMRPMSNMSAS 512
           LS+ + IDPSS++RAYAALGLPY                          G   M N++A 
Sbjct: 466 LSSPNPIDPSSMQRAYAALGLPYGNPAQGTGQQPAQTQVHQQIRNMNALGGNQM-NLTAG 524

Query: 513 PMGVNGGVGVQTPSLLSDSMLHSAINSQNPMMSE---NASVPSLGPMPTAAQPSTTGIRK 569
            M V      Q  +L+SD+ L +A+ + N ++S+    ++V + G MPTAA PS+TG+RK
Sbjct: 525 GMTVE-----QQTNLISDTALPTALANSNSLLSDGNGQSTVGNHGTMPTAAPPSSTGVRK 579

Query: 570 QWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEY 629
            WHE +TQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESAN+R EY
Sbjct: 580 AWHEHVTQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANSRDEY 639

Query: 630 YHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSXXXXXXXXXXXXXXTSNGPLP 689
           YH LAEKIYKIQKELEEKRR+RLQKQ ++ + A +                   +    P
Sbjct: 640 YHFLAEKIYKIQKELEEKRRSRLQKQGIMSSQAPLQAPGAQPTALTQTSPALGQTQPVRP 699

Query: 690 DPSMIRGSVPNQMMPRITPQSGLNQF-----GQMSMAQPPIVPRQTPPLQHHGQLAQPGA 744
               I  S+    M R+   SG+NQF     G + M   P+ PR   PL H  Q+   G+
Sbjct: 700 TNGPI--SMSTVPMNRMQVASGMNQFSNMPIGNVQMPTAPMGPRAASPLNHPAQINNMGS 757

Query: 745 LNPPMGYGP-RMQQP---------------SNQGQFLPQTQFPSQGMNVTNIPLAPSSGQ 788
           + P M   P RM QP                 Q QFL Q QFP+    ++       +G 
Sbjct: 758 V-PAMAMSPSRMSQPQPIIGAHAGSMIGPTQTQSQFLQQNQFPASAGTISVGLGQTGAGA 816

Query: 789 APVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQ 829
           A   Q Q  S+S P+++ +   G Q S +  P L Q  LHQ
Sbjct: 817 AVSQQGQAPSASLPISNSMNMLGPQTSQLPRPALSQSPLHQ 857



>gi|19173764|ref|NP_596894.1| E1A binding protein p300 [Rattus norvegicus]
 gi|15076626|dbj|BAB62425.1| E1A-binding protein [Rattus norvegicus]
          Length = 353

 Score =  502 bits (1293), Expect = e-140
 Identities = 300/353 (84%), Positives = 308/353 (87%), Gaps = 1/353 (0%)

Query: 1   MAENVVEPGPPSAKRPKXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
           MAENVVEPGPPSAKRPK           DGTDFGSLFDLEHDLPDELINSTELGLTNGGD
Sbjct: 1   MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60

Query: 61  INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS 120
           I+QLQTSLG+VQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQ+SPGL LINS
Sbjct: 61  ISQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQNSPGLSLINS 120

Query: 121 MVKSPMTQAGLTSPNMGMGTSGPNQGPTQST-GMMNSPVNQPAMGMNTGTNAGMNPGMLA 179
           MVKSPM Q GLTSPNMGMG+SGPNQGPTQST GMMNSPVNQPAMGMNTG NAGMNPGMLA
Sbjct: 121 MVKSPMAQTGLTSPNMGMGSSGPNQGPTQSTAGMMNSPVNQPAMGMNTGMNAGMNPGMLA 180

Query: 180 AGNGQGIMPNQVMNGSIGAGRGRQDMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGP 239
           AGNGQGIMPNQVMNGSIGAGRGR +MQYPN GMG+AG+LLTEPLQQGSPQMGGQ GLRGP
Sbjct: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEPLQQGSPQMGGQPGLRGP 240

Query: 240 QPLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVXXXXX 299
           Q  KMGMM+NP PYGSPYTQN GQQIGASGLGLQIQTKTVL NNLSPFAMDKKAV     
Sbjct: 241 QSHKMGMMSNPTPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVTGGGM 300

Query: 300 XXXXXXXXXXXXXXGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQ 352
                         GLV PVA GMGSGAHTADPEKRKLIQQQLVLLLHAHKCQ
Sbjct: 301 PNMGQQPTPSVQQPGLVNPVAPGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQ 353



>gi|1888540|gb|AAC51340.1| CREB-binding protein [Homo sapiens]
          Length = 932

 Score =  438 bits (1127), Expect = e-121
 Identities = 237/336 (70%), Positives = 254/336 (75%), Gaps = 1/336 (0%)

Query: 1476 SERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNV-XXXXXXXXXXXXXXXXXXXXXX 1534
            S RI+HDYKDIFKQATEDRLTSAKELPYFEGDFWPNV                       
Sbjct: 2    SGRIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAA 61

Query: 1535 XXSTDVTKGDXXXXXXXXXXXXXXXXXXLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEV 1594
              +T+ ++GD                  +SR NKKKP MPNVSNDLSQKLYATMEKHKEV
Sbjct: 62   SETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEV 121

Query: 1595 FFVIRLIAGPAANSXXXXXXXXXXXXXXXMDGRDAFLTLARDKHLEFSSLRRAQWSTMCM 1654
            FFVI L AGP  N+               MDGRDAFLTLARDKH EFSSLRR++WST+CM
Sbjct: 122  FFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCM 181

Query: 1655 LVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDD 1714
            LVELHTQ QDRFVYTCNECKHHVETRWHCTVC  YDLCI CYNTK+H HKM K GLGLDD
Sbjct: 182  LVELHTQGQDRFVYTCNECKHHVETRWHCTVCVVYDLCINCYNTKSHAHKMVKWGLGLDD 241

Query: 1715 ESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRK 1774
            E ++Q    ++SP +SRRLSIQRCIQSLVHACQCRNA CSLPSCQKMKRVVQHTKGCKRK
Sbjct: 242  EGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNAFCSLPSCQKMKRVVQHTKGCKRK 301

Query: 1775 TNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIK 1810
             NGGCP+CKQLIALCCYHAKHCQENKCPVPFCLNIK
Sbjct: 302  PNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIK 337




 Score = 65.5 bits (158), Expect = 1e-08
 Identities = 39/108 (36%), Positives = 48/108 (44%)

Query: 2269 MGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNXXXXXXXXXXXXXXXXXXXXXXX 2328
            +GSP QPNPMSPQQHML  Q Q+ HL GQQI  SLSN                       
Sbjct: 795  IGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPS 854

Query: 2329 XXXXXXXXXXXXXXXXXXXXXGLVAAQANPMEQGHFASPDQNSMLSQL 2376
                                 GL    A+ ++QGH  +P+Q++ML QL
Sbjct: 855  PRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQL 902




 Score = 58.9 bits (141), Expect = 1e-06
 Identities = 53/183 (28%), Positives = 74/183 (40%), Gaps = 29/183 (15%)

Query: 2010 MPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNXXXXXXXXXXXXXXXX 2069
            +PRP +   AQ       A   G     + P  P ++S  ALQ+                
Sbjct: 525  LPRPVISMQAQ-------AAVAGPRMPSVQP--PRSISPSALQDLLRTLKSPSSPQQQQQ 575

Query: 2070 XXXXXHANPQLLAAFIKQRAAKYANSNXXXXXXXXXXXXXXXXXXXXXXXXXXXVHSNPA 2129
                  +NPQL+AAFIKQR AKY  +                            +H  P+
Sbjct: 576  VLNILKSNPQLMAAFIKQRTAKYVANQ-------PGMQPQPGLQSQPGMQPQPGMHQQPS 628

Query: 2130 MQNMNPMQAGVQRAGXXXXXXXXXXXXXMGGMSPQAQQMNM-------NHNTMPSQFRDI 2182
            +QN+N MQAGV R G             MGG++PQ Q +N+       N  +M  Q+R++
Sbjct: 629  LQNLNAMQAGVPRPG------VPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREM 682

Query: 2183 LRR 2185
            LRR
Sbjct: 683  LRR 685



>gi|2996629|gb|AAC08447.1| CBP [Homo sapiens]
          Length = 555

 Score =  424 bits (1089), Expect = e-116
 Identities = 293/578 (50%), Positives = 356/578 (61%), Gaps = 51/578 (8%)

Query: 244 MGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVXXXXXXXXX 303
           MG+  N +P+G P++Q  GQ +GA+G+  Q+ +K  + N+L  F  D K           
Sbjct: 1   MGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPTDIKNT----SVTNV 56

Query: 304 XXXXXXXXXXGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQ 363
                     G+V   A   G    TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVR 
Sbjct: 57  PNMSQMQTSVGIVPTQAIATGP---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRA 113

Query: 364 CNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDK 423
           C+LPHCRTMKNVLNHMTHCQ+GK+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DK
Sbjct: 114 CSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDK 173

Query: 424 RNQQPILTGAPVGLGNP-SSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMXX 482
           RNQQ IL     G+ N   S+G GQQ+A +LS  + IDPSS++RAYAALGLPY +NQ   
Sbjct: 174 RNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPY-MNQ-PQ 231

Query: 483 XXXXXXXXXXXXXXXXXXXGMRPMSNMSASPMGVNGG---VGVQTPSLLSDSMLHSAINS 539
                               MR ++ +  +PM +  G      Q P+L+S+S L +++ +
Sbjct: 232 TQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGA 291

Query: 540 QNPMM---SENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPD 596
            NP+M   S + ++ +L  +PTAA PS+TG+RK WHE +TQDLR+HLVHKLVQAIFPTPD
Sbjct: 292 TNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPD 351

Query: 597 PAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQN 656
           PAALKDRRMENLVAYA+KVEGDMYESAN+R EYYHLLAEKIYKIQKELEEKRR+RL KQ 
Sbjct: 352 PAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQG 411

Query: 657 MLPNAAGMVPVSXXXXXXXXXXXXXXTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFG 716
           +L N   + P                  NGPL  P           + R+    G+N F 
Sbjct: 412 ILGNQPAL-PAPGAQPPVIPQAQPVRPPNGPLSLP-----------VNRMQVSQGMNSFN 459

Query: 717 QMSMA-----QPPIVPRQTPPLQHHGQLAQPGALNPPMGYGP-RMQQPSN---------- 760
            MS+      Q P+ PR   P+ H  Q+   G++ P M   P RM QP N          
Sbjct: 460 PMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSV-PGMAISPSRMPQPPNMMGAHTNNMM 518

Query: 761 -----QGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQ 793
                Q QFLPQ QFPS      ++ +     Q  VSQ
Sbjct: 519 AQAPAQSQFLPQNQFPSSS-GAMSVGMGQPPAQTGVSQ 555



>gi|28486618|ref|XP_128116.2| similar to E1A-associated protein p300 [Mus musculus]
          Length = 234

 Score =  394 bits (1013), Expect = e-108
 Identities = 170/171 (99%), Positives = 170/171 (99%)

Query: 1342 RFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSV 1401
            RFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSV
Sbjct: 10   RFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSV 69

Query: 1402 HFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPK 1461
            HFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPK
Sbjct: 70   HFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPK 129

Query: 1462 RLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNV 1512
            RLQEWYKKMLDKAVSERIVHDYKDI KQATEDRLTSAKELPYFEGDFWPNV
Sbjct: 130  RLQEWYKKMLDKAVSERIVHDYKDILKQATEDRLTSAKELPYFEGDFWPNV 180



>gi|3168627|gb|AAC17736.1| CBP [Homo sapiens]
          Length = 923

 Score =  340 bits (872), Expect = 2e-91
 Identities = 179/248 (72%), Positives = 194/248 (78%), Gaps = 11/248 (4%)

Query: 1574 PNVSND-----------LSQKLYATMEKHKEVFFVIRLIAGPAANSXXXXXXXXXXXXXX 1622
            PNV  +             ++      +  EVFFVI L AGP  N+              
Sbjct: 81   PNVLEESIKELEQEEEERKKEESTAASETTEVFFVIHLHAGPVINTLPPIVDPDPLLSCD 140

Query: 1623 XMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWH 1682
             MDGRDAFLTLARDKH EFSSLRR++WST+CMLVELHTQ QDRFVYTCNECKHHVETRWH
Sbjct: 141  LMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWH 200

Query: 1683 CTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSL 1742
            CTVCEDYDLCI CYNTK+H HKM K GLGLDDE ++Q    ++SP +SRRLSIQRCIQSL
Sbjct: 201  CTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSL 260

Query: 1743 VHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCP 1802
            VHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCP+CKQLIALCCYHAKHCQENKCP
Sbjct: 261  VHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCP 320

Query: 1803 VPFCLNIK 1810
            VPFCLNIK
Sbjct: 321  VPFCLNIK 328




 Score =  164 bits (416), Expect = 2e-38
 Identities = 79/83 (95%), Positives = 81/83 (97%)

Query: 1430 YTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQ 1489
            Y TGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKA +ERI+HDYKDIFKQ
Sbjct: 1    YVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQ 60

Query: 1490 ATEDRLTSAKELPYFEGDFWPNV 1512
            ATEDRLTSAKELPYFEGDFWPNV
Sbjct: 61   ATEDRLTSAKELPYFEGDFWPNV 83




 Score = 65.5 bits (158), Expect = 1e-08
 Identities = 39/108 (36%), Positives = 48/108 (44%)

Query: 2269 MGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNXXXXXXXXXXXXXXXXXXXXXXX 2328
            +GSP QPNPMSPQQHML  Q Q+ HL GQQI  SLSN                       
Sbjct: 786  IGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPS 845

Query: 2329 XXXXXXXXXXXXXXXXXXXXXGLVAAQANPMEQGHFASPDQNSMLSQL 2376
                                 GL    A+ ++QGH  +P+Q++ML QL
Sbjct: 846  PRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQL 893




 Score = 58.9 bits (141), Expect = 1e-06
 Identities = 53/183 (28%), Positives = 74/183 (40%), Gaps = 29/183 (15%)

Query: 2010 MPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNXXXXXXXXXXXXXXXX 2069
            +PRP +   AQ       A   G     + P  P ++S  ALQ+                
Sbjct: 516  LPRPVISMQAQ-------AAVAGPRMPSVQP--PRSISPSALQDLLRTLKSPSSPQQQQQ 566

Query: 2070 XXXXXHANPQLLAAFIKQRAAKYANSNXXXXXXXXXXXXXXXXXXXXXXXXXXXVHSNPA 2129
                  +NPQL+AAFIKQR AKY  +                            +H  P+
Sbjct: 567  VLNILKSNPQLMAAFIKQRTAKYVANQ-------PGMQPQPGLQSQPGMQPQPGMHQQPS 619

Query: 2130 MQNMNPMQAGVQRAGXXXXXXXXXXXXXMGGMSPQAQQMNM-------NHNTMPSQFRDI 2182
            +QN+N MQAGV R G             MGG++PQ Q +N+       N  +M  Q+R++
Sbjct: 620  LQNLNAMQAGVPRPG------VPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREM 673

Query: 2183 LRR 2185
            LRR
Sbjct: 674  LRR 676



>gi|27667568|ref|XP_213219.1| similar to CREB-binding protein [Mus musculus] [Rattus norvegicus]
          Length = 132

 Score =  281 bits (720), Expect = 9e-74
 Identities = 126/131 (96%), Positives = 130/131 (99%)

Query: 1059 MPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYV 1118
            MPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK+PMDLSTIKRKLDTGQYQEPWQYV
Sbjct: 1    MPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYV 60

Query: 1119 DDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCY 1178
            DD+WLMFNNAWLYNRKTSRVYK+CSKL+EVFEQEIDPVMQSLGYCCGRK EFSPQTLCCY
Sbjct: 61   DDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCY 120

Query: 1179 GKQLCTIPRDA 1189
            GKQLCTIPRDA
Sbjct: 121  GKQLCTIPRDA 131



>gi|21105780|gb|AAM34788.1|AF512558_2 HAC5 [Arabidopsis thaliana]
          Length = 1012

 Score =  258 bits (659), Expect = 1e-66
 Identities = 149/387 (38%), Positives = 217/387 (56%), Gaps = 50/387 (12%)

Query: 1163 CCGRKLEFSPQTLCCYGKQLCTIPRDATYYSY---QNRYHFCEKCFNEIQGESVSLGDDP 1219
            C   +L F P  + C       + R+A +Y+    ++R++ C  C+NE +  +VS+   P
Sbjct: 405  CAVERLAFEPTPIYCTPCG-ARVKRNAMHYTVVAGESRHYVCIPCYNEARANTVSVDGTP 463

Query: 1220 SQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHH--EIIWPAGFVCDGCLK 1277
                  + K +F K+KND    E +V+C +C    HQIC L +       A + C  C  
Sbjct: 464  ------VPKSRFEKKKNDEEVEESWVQCDKCQAWQHQICALFNGRRNHGQAEYTCPNCYI 517

Query: 1278 KSARTRKENKFS------AKRLPSTRLGTFLENRVNDFLRRQNH-------------PES 1318
            +     +    S      AK LP++ L   LE R+   L+++               P +
Sbjct: 518  QEVEQGERKPVSQNVILGAKSLPASTLSNHLEQRLFKKLKQERQERARLQGKSYEEVPGA 577

Query: 1319 GEVTVRVVHASDKTVEVKPGMKARFVD---SGEMAESFPYRTKALFAFEEIDGVDLCFFG 1375
              + +RVV + DK +EVKP    RF+D       +  FPY++KA+  F++I+GV++C FG
Sbjct: 578  DSLVIRVVASVDKILEVKP----RFLDIFREDNYSSEFPYKSKAILLFQKIEGVEVCLFG 633

Query: 1376 MHVQEYGSDCPPPNQRRVYISYLDSVHFFRP-------KCLRTAVYHEILIGYLEYVKKL 1428
            M+VQE+G+D   PNQRRVY+SYLDSV +FRP       + LRT VYHEILIGYL+Y KK 
Sbjct: 634  MYVQEFGTDSASPNQRRVYLSYLDSVKYFRPDVRTVSGEALRTFVYHEILIGYLDYCKKR 693

Query: 1429 GYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHD----YK 1484
            G+++ +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  E++V +    Y 
Sbjct: 694  GFSSCYIWACPPLKGEDYILYCHPEIQKTPKTDKLREWYLAMLKKASKEKVVVECTNFYD 753

Query: 1485 DIFKQATEDRL-TSAKELPYFEGDFWP 1510
              F Q+ E R   +A  LPYF+GD+WP
Sbjct: 754  HFFVQSGECRAKVTAARLPYFDGDYWP 780




 Score = 70.9 bits (172), Expect = 3e-10
 Identities = 34/82 (41%), Positives = 47/82 (57%), Gaps = 3/82 (3%)

Query: 1625 DGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETR--WH 1682
            D R AFL+L +  H ++ +LRRA+ S+M +L  LH  +   F   C  C+  +ET   W 
Sbjct: 931  DTRQAFLSLCQGNHYQYDTLRRAKHSSMMILYHLHNPTVPAFAMACAICQQELETAQGWR 990

Query: 1683 CTVCEDYDLCITCYNTK-NHDH 1703
            C VC DYD+C  CY+   NH H
Sbjct: 991  CEVCPDYDVCNACYSKGINHPH 1012




 Score = 60.5 bits (145), Expect = 4e-07
 Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 7/86 (8%)

Query: 342 LVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIIS 401
           L+ LLH  KC   E        C   +C T K +L H+  C++  +C   +C  +RQ+I 
Sbjct: 94  LLFLLHVRKCNAAED------NCESKYCFTAKTLLKHINCCKA-PACAYQYCHQTRQLIH 146

Query: 402 HWKNCTRHDCPVCLPLKNAGDKRNQQ 427
           H+K+C    CPVC+ +KN  +K+ ++
Sbjct: 147 HYKHCGDEACPVCVFVKNFKEKQKEK 172



>gi|15230656|ref|NP_187904.1| CREB-binding protein -related [Arabidopsis thaliana]
 gi|15795129|dbj|BAB02507.1| CREB-binding protein-like [Arabidopsis thaliana]
          Length = 1670

 Score =  251 bits (640), Expect = 2e-64
 Identities = 149/387 (38%), Positives = 217/387 (56%), Gaps = 50/387 (12%)

Query: 1163 CCGRKLEFSPQTLCCYGKQLCTIPRDATYYSY---QNRYHFCEKCFNEIQGESVSLGDDP 1219
            C   +L F P  + C       + R+A +Y+    ++R++ C  C+NE +  +VS+   P
Sbjct: 933  CAVERLAFEPTPIYCTPCG-ARVKRNAMHYTVVAGESRHYVCIPCYNEARANTVSVDGTP 991

Query: 1220 SQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHH--EIIWPAGFVCDGCLK 1277
                  + K +F K+KND    E +V+C +C    HQIC L +       A + C  C  
Sbjct: 992  ------VPKSRFEKKKNDEEVEESWVQCDKCQAWQHQICALFNGRRNHGQAEYTCPNCYI 1045

Query: 1278 KSARTRKENKFS------AKRLPSTRLGTFLENRVNDFLRRQNH-------------PES 1318
            +     +    S      AK LP++ L   LE R+   L+++               P +
Sbjct: 1046 QEVEQGERKPVSQNVILGAKSLPASTLSNHLEQRLFKKLKQERQERARLQGKSYEEVPGA 1105

Query: 1319 GEVTVRVVHASDKTVEVKPGMKARFVD---SGEMAESFPYRTKALFAFEEIDGVDLCFFG 1375
              + +RVV + DK +EVKP    RF+D       +  FPY++KA+  F++I+GV++C FG
Sbjct: 1106 DSLVIRVVASVDKILEVKP----RFLDIFREDNYSSEFPYKSKAILLFQKIEGVEVCLFG 1161

Query: 1376 MHVQEYGSDCPPPNQRRVYISYLDSVHFFRP-------KCLRTAVYHEILIGYLEYVKKL 1428
            M+VQE+G+D   PNQRRVY+SYLDSV +FRP       + LRT VYHEILIGYL+Y KK 
Sbjct: 1162 MYVQEFGTDSASPNQRRVYLSYLDSVKYFRPDVRTVSGEALRTFVYHEILIGYLDYCKKR 1221

Query: 1429 GYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHD----YK 1484
            G+++ +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  E++V +    Y 
Sbjct: 1222 GFSSCYIWACPPLKGEDYILYCHPEIQKTPKTDKLREWYLAMLKKASKEKVVVECTNFYD 1281

Query: 1485 DIFKQATEDRL-TSAKELPYFEGDFWP 1510
              F Q+ E R   +A  LPYF+GD+WP
Sbjct: 1282 HFFVQSGECRAKVTAARLPYFDGDYWP 1308




 Score =  107 bits (267), Expect = 3e-21
 Identities = 60/189 (31%), Positives = 95/189 (50%), Gaps = 15/189 (7%)

Query: 1625 DGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETR--WH 1682
            D R AFL+L +  H ++ +LRRA+ S+M +L  LH  +   F   C  C+  +ET   W 
Sbjct: 1459 DTRQAFLSLCQGNHYQYDTLRRAKHSSMMILYHLHNPTVPAFAMACAICQQELETAQGWR 1518

Query: 1683 CTVCEDYDLCITCYNTK-NHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQS 1741
            C VC DYD+C  CY+   NH H +       D    N Q    Q+          +  + 
Sbjct: 1519 CEVCPDYDVCNACYSKGINHPHSIISRPSATDSVVQNTQTNQIQN---------AQLREV 1569

Query: 1742 LVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKC 1801
            L+H   C  A C  P C+ +K +++H   CK +   GC  CK++ +L   H+++C++ +C
Sbjct: 1570 LLHVMTCCTAQCQYPRCRVIKGLIRHGLVCKTR---GCIACKKMWSLFRLHSRNCRDPQC 1626

Query: 1802 PVPFCLNIK 1810
             VP C  ++
Sbjct: 1627 KVPKCRELR 1635




 Score = 58.9 bits (141), Expect = 1e-06
 Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 7/86 (8%)

Query: 342 LVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIIS 401
           L+ LLH  KC   E        C   +C T K +L H+  C++  +C   +C  +RQ+I 
Sbjct: 622 LLFLLHVRKCNAAED------NCESKYCFTAKTLLKHINCCKA-PACAYQYCHQTRQLIH 674

Query: 402 HWKNCTRHDCPVCLPLKNAGDKRNQQ 427
           H+K+C    CPVC+ +KN  +K+ ++
Sbjct: 675 HYKHCGDEACPVCVFVKNFKEKQKEK 700



>gi|7487910|pir||T01055 hypothetical protein YUP8H12R.38 - Arabidopsis thaliana
 gi|3152587|gb|AAC17068.1| Similar to CREB-binding protein homolog gb|U88570 from D.
            melanogaster and contains similarity to callus-associated
            protein gb|U01961 from Nicotiana tabacum.  EST gb|W43427
            comes from this gene. [Arabidopsis thaliana]
          Length = 1516

 Score =  246 bits (628), Expect = 4e-63
 Identities = 152/385 (39%), Positives = 209/385 (54%), Gaps = 45/385 (11%)

Query: 1163 CCGRKLEFSPQTLCCYGKQLCTIPRDATYYSY---QNRYHFCEKCFNEIQGESVSLGDDP 1219
            C   KL F P  + C       I R+A YY+      R++FC  C+NE +G+++ L +  
Sbjct: 832  CAVEKLTFEPPPIYCTPCG-ARIKRNAMYYTVGAGDTRHYFCIPCYNESRGDTI-LAEGT 889

Query: 1220 SQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHH---------EIIWPAGF 1270
              P     K +  K+KND    E +V+C +C    HQIC L +         E   P  F
Sbjct: 890  PMP-----KARLEKKKNDEETEEWWVQCDKCEAWQHQICALFNGRRNDGGQAEYTCPYCF 944

Query: 1271 VCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNH-------------PE 1317
            + +    K     +     AK LP T L   +E R+   L+++               P 
Sbjct: 945  IAEVEQSKRKPLPQSAVLGAKDLPRTILSDHIEQRLFKRLKQERTERARAQGKSYDEIPT 1004

Query: 1318 SGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMH 1377
            +  + +RVV + DK +EVKP     F +     E F Y++K +  F++I+GV++C FGM+
Sbjct: 1005 AESLVIRVVSSVDKKLEVKPRFLEIFREDSYPTE-FAYKSKVVLLFQKIEGVEVCLFGMY 1063

Query: 1378 VQEYGSDCPPPNQRRVYISYLDSVHFFRP-------KCLRTAVYHEILIGYLEYVKKLGY 1430
            VQE+GS+C  PNQRRVY+SYLDSV +FRP       + LRT VYHEILIGYLEY K  G+
Sbjct: 1064 VQEFGSECAFPNQRRVYLSYLDSVKYFRPEVRSYNGEALRTFVYHEILIGYLEYCKLRGF 1123

Query: 1431 TTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHD----YKDI 1486
            T+ +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  E IV +    Y   
Sbjct: 1124 TSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLAMLRKASKEGIVAETINLYDHF 1183

Query: 1487 FKQATEDRL-TSAKELPYFEGDFWP 1510
            F Q  E R   +A  LPYF+GD+WP
Sbjct: 1184 FMQTGECRAKVTAARLPYFDGDYWP 1208




 Score =  140 bits (352), Expect = 3e-31
 Identities = 79/229 (34%), Positives = 122/229 (53%), Gaps = 16/229 (6%)

Query: 1583 KLYATMEKHKEVFFVIRLIAGPAANSXXXXXXXXXXXXXXXMDGRDAFLTLARDKHLEFS 1642
            +L  T+   KE F ++ ++  PA                   D R AFL+L +  H ++ 
Sbjct: 1298 QLGETIHPMKEDFIMVEIMDIPA-----DTRDKDEILESEFFDTRQAFLSLCQGNHYQYD 1352

Query: 1643 SLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVET--RWHCTVCEDYDLCITCYNTK- 1699
            +LRRA+ S+M +L  LH  +   FV TCN C   +ET   W C VC DYD+C  C++   
Sbjct: 1353 TLRRAKHSSMMVLYHLHNPTAPAFVTTCNACHLDIETGQGWRCEVCPDYDVCNACFSRDG 1412

Query: 1700 --NHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPS 1757
              NH HK+       D  + N++A         R L +++ +  LVHA QCR+A+C  P+
Sbjct: 1413 GVNHPHKLTNHPSLADQNAQNKEARQL------RVLQLRKMLDLLVHASQCRSAHCQYPN 1466

Query: 1758 CQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFC 1806
            C+K+K + +H   CK + +GGC +CK++  L   HA+ C+E++C VP C
Sbjct: 1467 CRKVKGLFRHGINCKVRASGGCVLCKKMWYLLQLHARACKESECHVPRC 1515




 Score = 51.6 bits (122), Expect = 2e-04
 Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 8/101 (7%)

Query: 318 PVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLN 377
           P A    +G    DP + K  Q+ L+ L HA  C+  E       +C   +C T++ +  
Sbjct: 498 PTATTCRNGNGNRDP-RFKNQQKWLLFLRHARHCKAPEG------KCPDRNCVTVQKLWK 550

Query: 378 HMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 418
           HM  C +   C    C  ++ +I+H ++C   +CPVC+P+K
Sbjct: 551 HMDSC-AAPQCSYPRCLPTKTLINHHRSCKEPNCPVCIPVK 590



>gi|23200188|pdb|1JSP|B Chain B, Nmr Structure Of Cbp Bromodomain In Complex With P53 Peptide
          Length = 121

 Score =  244 bits (622), Expect = 2e-62
 Identities = 112/117 (95%), Positives = 117/117 (100%)

Query: 1045 KKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKR 1104
            +KKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK+PMDLSTIKR
Sbjct: 5    RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR 64

Query: 1105 KLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLG 1161
            KLDTGQYQEPWQYVDD+WLMFNNAWLYNRKTSRVYK+CSKL+EVFEQEIDPVMQSLG
Sbjct: 65   KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG 121



>gi|18412221|ref|NP_565197.1| p300/CBP acetyltransferase-related protein 2 [Arabidopsis thaliana]
 gi|12597461|gb|AAG60059.1| p300/CBP acetyltransferase-related protein 2 [Arabidopsis thaliana]
          Length = 1654

 Score =  244 bits (622), Expect = 2e-62
 Identities = 152/385 (39%), Positives = 209/385 (54%), Gaps = 45/385 (11%)

Query: 1163 CCGRKLEFSPQTLCCYGKQLCTIPRDATYYSY---QNRYHFCEKCFNEIQGESVSLGDDP 1219
            C   KL F P  + C       I R+A YY+      R++FC  C+NE +G+++ L +  
Sbjct: 946  CAVEKLTFEPPPIYCTPCG-ARIKRNAMYYTVGAGDTRHYFCIPCYNESRGDTI-LAEGT 1003

Query: 1220 SQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHH---------EIIWPAGF 1270
              P     K +  K+KND    E +V+C +C    HQIC L +         E   P  F
Sbjct: 1004 PMP-----KARLEKKKNDEETEEWWVQCDKCEAWQHQICALFNGRRNDGGQAEYTCPYCF 1058

Query: 1271 VCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNH-------------PE 1317
            + +    K     +     AK LP T L   +E R+   L+++               P 
Sbjct: 1059 IAEVEQSKRKPLPQSAVLGAKDLPRTILSDHIEQRLFKRLKQERTERARAQGKSYDEIPT 1118

Query: 1318 SGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMH 1377
            +  + +RVV + DK +EVKP     F +     E F Y++K +  F++I+GV++C FGM+
Sbjct: 1119 AESLVIRVVSSVDKKLEVKPRFLEIFREDSYPTE-FAYKSKVVLLFQKIEGVEVCLFGMY 1177

Query: 1378 VQEYGSDCPPPNQRRVYISYLDSVHFFRP-------KCLRTAVYHEILIGYLEYVKKLGY 1430
            VQE+GS+C  PNQRRVY+SYLDSV +FRP       + LRT VYHEILIGYLEY K  G+
Sbjct: 1178 VQEFGSECAFPNQRRVYLSYLDSVKYFRPEVRSYNGEALRTFVYHEILIGYLEYCKLRGF 1237

Query: 1431 TTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHD----YKDI 1486
            T+ +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  E IV +    Y   
Sbjct: 1238 TSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLAMLRKASKEGIVAETINLYDHF 1297

Query: 1487 FKQATEDRL-TSAKELPYFEGDFWP 1510
            F Q  E R   +A  LPYF+GD+WP
Sbjct: 1298 FMQTGECRAKVTAARLPYFDGDYWP 1322




 Score =  139 bits (349), Expect = 1e-30
 Identities = 72/187 (38%), Positives = 109/187 (58%), Gaps = 11/187 (5%)

Query: 1625 DGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVET--RWH 1682
            D R AFL+L +  H ++ +LRRA+ S+M +L  LH  +   FV TCN C   +ET   W 
Sbjct: 1473 DTRQAFLSLCQGNHYQYDTLRRAKHSSMMVLYHLHNPTAPAFVTTCNACHLDIETGQGWR 1532

Query: 1683 CTVCEDYDLCITCYNTK---NHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCI 1739
            C VC DYD+C  C++     NH HK+       D  + N++A         R L +++ +
Sbjct: 1533 CEVCPDYDVCNACFSRDGGVNHPHKLTNHPSLADQNAQNKEARQL------RVLQLRKML 1586

Query: 1740 QSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQEN 1799
              LVHA QCR+A+C  P+C+K+K + +H   CK + +GGC +CK++  L   HA+ C+E+
Sbjct: 1587 DLLVHASQCRSAHCQYPNCRKVKGLFRHGINCKVRASGGCVLCKKMWYLLQLHARACKES 1646

Query: 1800 KCPVPFC 1806
            +C VP C
Sbjct: 1647 ECHVPRC 1653




 Score = 51.2 bits (121), Expect = 3e-04
 Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 8/101 (7%)

Query: 318 PVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLN 377
           P A    +G    DP + K  Q+ L+ L HA  C+  E       +C   +C T++ +  
Sbjct: 612 PTATTCRNGNGNRDP-RFKNQQKWLLFLRHARHCKAPEG------KCPDRNCVTVQKLWK 664

Query: 378 HMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 418
           HM  C +   C    C  ++ +I+H ++C   +CPVC+P+K
Sbjct: 665 HMDSC-AAPQCSYPRCLPTKTLINHHRSCKEPNCPVCIPVK 704



>gi|18408717|ref|NP_564891.1| hypothetical protein [Arabidopsis thaliana]
 gi|25404951|pir||B96696 protein F1N21.4 [imported] - Arabidopsis thaliana
 gi|9828615|gb|AAG00238.1|AC002130_3 F1N21.4 [Arabidopsis thaliana]
          Length = 1357

 Score =  236 bits (603), Expect = 3e-60
 Identities = 141/395 (35%), Positives = 206/395 (52%), Gaps = 53/395 (13%)

Query: 1158 QSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSY--------QNRYHFCEKCFNEIQ 1209
            +S   C    L F PQ L C    LC+   D   + Y          ++  C  C +  +
Sbjct: 643  ESCQLCDDGTLLFPPQPLYCL---LCSRRIDDRSFYYTPGEEELSNAQHQICSPCHSRCK 699

Query: 1210 GESVSLGDDPSQPQTTINKEQFSKRKN-DTLDPELFVECTECGRKMHQICVLHHEII--- 1265
             +    G         I+K +  KR N D  D E +V+C  C +  HQIC L++++    
Sbjct: 700  TKFPLCG-------VFIDKHKMLKRSNFDNADTEEWVQCESCEKWQHQICGLYNKLKDED 752

Query: 1266 WPAGFVCDGCLKKSARTRKENKF------SAKRLPSTRLGTFLENRVNDFLRRQNH---- 1315
              A ++C  CL +  ++             AK LP T L  FLE R+   L+ + +    
Sbjct: 753  KTAEYICPTCLLEECQSINNMALVDYTDSGAKDLPETVLSYFLEQRLFKRLKEERYQTAK 812

Query: 1316 ---------PESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEI 1366
                     PE   +T+RVV ++D+T+ V     A  +        FPYR+K +  F+++
Sbjct: 813  ATGKSINDVPEPEGLTLRVVFSADRTLTVNKQF-ASLLHKENFPSEFPYRSKVILLFQKV 871

Query: 1367 DGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRP-------KCLRTAVYHEILI 1419
             GVD+C F + VQE+GS+C  PNQR  YI YLDSV +F+P       + LRT VYHE+LI
Sbjct: 872  HGVDICIFALFVQEFGSECSQPNQRSTYIFYLDSVKYFKPERVTFAGEALRTFVYHEVLI 931

Query: 1420 GYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERI 1479
            GYLEY K  G+TT +IWACPP  G DYI + HP  Q+ P  K+L++WY  ML KA  +R+
Sbjct: 932  GYLEYCKLRGFTTSYIWACPPKIGQDYIMYSHPKTQQTPDTKKLRKWYVSMLQKAAEQRV 991

Query: 1480 VHDYKDIFKQ---ATEDRLTSAKELPYFEGDFWPN 1511
            V +  +++ +   +TE+ +T+A+ LPYFEG FW N
Sbjct: 992  VMNVTNLYDRFFDSTEEYMTAAR-LPYFEGSFWSN 1025




 Score = 93.6 bits (231), Expect = 5e-17
 Identities = 64/197 (32%), Positives = 91/197 (46%), Gaps = 30/197 (15%)

Query: 1625 DGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQ-----SQDRFVYTCNECKHHVET 1679
            + R AFL  ++  +  F +LR A+ S+M +L  LHT      SQ+    TC  CK  V T
Sbjct: 1175 ESRQAFLAFSQKHNYNFHTLRHAKHSSMMILHHLHTSNKHHCSQNSSSLTCTACKKDVST 1234

Query: 1680 RWH--CTVCEDYDLCITCYNTKN----HDHKMEKLGLGLDDESNNQQAAATQSPGDSRRL 1733
              +  C +C DY  C  CY TKN    H H    L             +A ++P  SR +
Sbjct: 1235 TIYFPCLLCPDYRACTGCY-TKNRTLRHLHIFPTL------------PSANRAP--SRTV 1279

Query: 1734 SIQRCIQSLVHACQCRN---ANCSLPSCQKMKRVVQHTKGCK-RKTNGGCPICKQLIALC 1789
             +   + ++ HA  C++    +CS P C ++K +  H   CK RK    C  C +L    
Sbjct: 1280 MVLEILNAISHALLCQHKTTKSCSYPKCHEVKALFTHNVQCKIRKKGTRCNTCYKLWQTI 1339

Query: 1790 CYHAKHCQENKCPVPFC 1806
              H  HCQ+  CPVP C
Sbjct: 1340 RIHVYHCQDLNCPVPQC 1356



>gi|25518555|pir||E86302 hypothetical protein F17F16.8 [imported] - Arabidopsis thaliana
 gi|9954734|gb|AAG09087.1|AC026237_8 Unknown Protein [Arabidopsis thaliana]
          Length = 1498

 Score =  236 bits (602), Expect = 4e-60
 Identities = 154/388 (39%), Positives = 212/388 (54%), Gaps = 51/388 (13%)

Query: 1163 CCGRKLEFSPQTLCCYGKQLCTIPRDATYYSY---QNRYHFCEKCFNEIQGESVSLGDDP 1219
            C   KL F P  + C       I R+A YY+    + R++FC  C+NE +G+++ L +  
Sbjct: 753  CAVEKLTFEPPPIYCTPCG-ARIKRNAMYYTVGGGETRHYFCIPCYNESRGDTI-LAEGT 810

Query: 1220 SQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHH---------EIIWPAGF 1270
            S P     K +  K+KND    E +V+C +C    HQIC L +         E   P  +
Sbjct: 811  SMP-----KAKLEKKKNDEEIEESWVQCDKCQAWQHQICALFNGRRNDGGQAEYTCPYCY 865

Query: 1271 VCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNH-------------PE 1317
            V D    +     +     AK LP T L   +E R+   L+++               P 
Sbjct: 866  VIDVEQNERKPLLQSAVLGAKDLPRTILSDHIEQRLFKRLKQERTERARVQGTSYDEIPT 925

Query: 1318 SGEVTVRVVHASDKTVEVKPGMKARFVD---SGEMAESFPYRTKALFAFEEIDGVDLCFF 1374
               + VRVV + DK +EV    K+RF++          FPY++K +  F++I+GV++C F
Sbjct: 926  VESLVVRVVSSVDKKLEV----KSRFLEIFREDNFPTEFPYKSKVVLLFQKIEGVEVCLF 981

Query: 1375 GMHVQEYGSDCPPPNQRRVYISYLDSVHFFRP-------KCLRTAVYHEILIGYLEYVKK 1427
            GM+VQE+GS+C  PNQRRVY+SYLDSV +FRP       + LRT VYHEILIGYLEY K 
Sbjct: 982  GMYVQEFGSECSNPNQRRVYLSYLDSVKYFRPDIKSANGEALRTFVYHEILIGYLEYCKL 1041

Query: 1428 LGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHD----Y 1483
             G+T+ +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  E IV +    Y
Sbjct: 1042 RGFTSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLAMLRKAAKEGIVAETTNLY 1101

Query: 1484 KDIFKQATEDRL-TSAKELPYFEGDFWP 1510
               F Q  E R   +A  LPYF+GD+WP
Sbjct: 1102 DHFFLQTGECRAKVTAARLPYFDGDYWP 1129




 Score =  135 bits (340), Expect = 9e-30
 Identities = 72/191 (37%), Positives = 110/191 (57%), Gaps = 11/191 (5%)

Query: 1625 DGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVET--RWH 1682
            D R AFL+L +  H ++ +LRRA+ S+M +L  LH  +   FV TCN C   +E+   W 
Sbjct: 1280 DTRQAFLSLCQGNHYQYDTLRRAKHSSMMVLYHLHNPTAPAFVTTCNVCHLDIESGLGWR 1339

Query: 1683 CTVCEDYDLCITCYNTK---NHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCI 1739
            C VC DYD+C  CY  +   NH HK+       D  + N++A         R L +++ +
Sbjct: 1340 CEVCPDYDVCNACYKKEGCINHPHKLTTHPSLADQNAQNKEARQL------RVLQLRKML 1393

Query: 1740 QSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQEN 1799
              LVHA QCR+  C  P+C+K+K + +H   CK + +GGC +CK++  L   HA+ C+E+
Sbjct: 1394 DLLVHASQCRSPVCLYPNCRKVKGLFRHGLRCKVRASGGCVLCKKMWYLLQLHARACKES 1453

Query: 1800 KCPVPFCLNIK 1810
            +C VP C ++K
Sbjct: 1454 ECDVPRCGDLK 1464




 Score = 50.1 bits (118), Expect = 5e-04
 Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 8/95 (8%)

Query: 331 DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQV 390
           DP K K  Q+ L+ L HA  C+      G   +C   +C T++ + +HM +C +   C  
Sbjct: 430 DP-KFKNQQRWLLFLRHARSCK---PPGG---RCQDQNCVTVQKLWSHMDNC-ADPQCLY 481

Query: 391 AHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRN 425
             C  ++ +I H+KNC    CPVC+P+K    + N
Sbjct: 482 PRCRHTKALIGHYKNCKDPRCPVCVPVKTYQQQAN 516



>gi|15219327|ref|NP_173115.1| expressed protein [Arabidopsis thaliana]
          Length = 1706

 Score =  234 bits (598), Expect = 1e-59
 Identities = 154/388 (39%), Positives = 212/388 (54%), Gaps = 51/388 (13%)

Query: 1163 CCGRKLEFSPQTLCCYGKQLCTIPRDATYYSY---QNRYHFCEKCFNEIQGESVSLGDDP 1219
            C   KL F P  + C       I R+A YY+    + R++FC  C+NE +G+++ L +  
Sbjct: 961  CAVEKLTFEPPPIYCTPCG-ARIKRNAMYYTVGGGETRHYFCIPCYNESRGDTI-LAEGT 1018

Query: 1220 SQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHH---------EIIWPAGF 1270
            S P     K +  K+KND    E +V+C +C    HQIC L +         E   P  +
Sbjct: 1019 SMP-----KAKLEKKKNDEEIEESWVQCDKCQAWQHQICALFNGRRNDGGQAEYTCPYCY 1073

Query: 1271 VCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNH-------------PE 1317
            V D    +     +     AK LP T L   +E R+   L+++               P 
Sbjct: 1074 VIDVEQNERKPLLQSAVLGAKDLPRTILSDHIEQRLFKRLKQERTERARVQGTSYDEIPT 1133

Query: 1318 SGEVTVRVVHASDKTVEVKPGMKARFVD---SGEMAESFPYRTKALFAFEEIDGVDLCFF 1374
               + VRVV + DK +EV    K+RF++          FPY++K +  F++I+GV++C F
Sbjct: 1134 VESLVVRVVSSVDKKLEV----KSRFLEIFREDNFPTEFPYKSKVVLLFQKIEGVEVCLF 1189

Query: 1375 GMHVQEYGSDCPPPNQRRVYISYLDSVHFFRP-------KCLRTAVYHEILIGYLEYVKK 1427
            GM+VQE+GS+C  PNQRRVY+SYLDSV +FRP       + LRT VYHEILIGYLEY K 
Sbjct: 1190 GMYVQEFGSECSNPNQRRVYLSYLDSVKYFRPDIKSANGEALRTFVYHEILIGYLEYCKL 1249

Query: 1428 LGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHD----Y 1483
             G+T+ +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  E IV +    Y
Sbjct: 1250 RGFTSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLAMLRKAAKEGIVAETTNLY 1309

Query: 1484 KDIFKQATEDRL-TSAKELPYFEGDFWP 1510
               F Q  E R   +A  LPYF+GD+WP
Sbjct: 1310 DHFFLQTGECRAKVTAARLPYFDGDYWP 1337




 Score =  135 bits (339), Expect = 1e-29
 Identities = 72/191 (37%), Positives = 110/191 (57%), Gaps = 11/191 (5%)

Query: 1625 DGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVET--RWH 1682
            D R AFL+L +  H ++ +LRRA+ S+M +L  LH  +   FV TCN C   +E+   W 
Sbjct: 1488 DTRQAFLSLCQGNHYQYDTLRRAKHSSMMVLYHLHNPTAPAFVTTCNVCHLDIESGLGWR 1547

Query: 1683 CTVCEDYDLCITCYNTK---NHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCI 1739
            C VC DYD+C  CY  +   NH HK+       D  + N++A         R L +++ +
Sbjct: 1548 CEVCPDYDVCNACYKKEGCINHPHKLTTHPSLADQNAQNKEARQL------RVLQLRKML 1601

Query: 1740 QSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQEN 1799
              LVHA QCR+  C  P+C+K+K + +H   CK + +GGC +CK++  L   HA+ C+E+
Sbjct: 1602 DLLVHASQCRSPVCLYPNCRKVKGLFRHGLRCKVRASGGCVLCKKMWYLLQLHARACKES 1661

Query: 1800 KCPVPFCLNIK 1810
            +C VP C ++K
Sbjct: 1662 ECDVPRCGDLK 1672




 Score = 50.1 bits (118), Expect = 6e-04
 Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 8/95 (8%)

Query: 331 DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQV 390
           DP K K  Q+ L+ L HA  C+      G   +C   +C T++ + +HM +C +   C  
Sbjct: 638 DP-KFKNQQRWLLFLRHARSCK---PPGG---RCQDQNCVTVQKLWSHMDNC-ADPQCLY 689

Query: 391 AHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRN 425
             C  ++ +I H+KNC    CPVC+P+K    + N
Sbjct: 690 PRCRHTKALIGHYKNCKDPRCPVCVPVKTYQQQAN 724



>gi|5042442|gb|AAD38279.1|AC007789_5 putative CREB-binding protein [Oryza sativa (japonica
            cultivar-group)]
          Length = 994

 Score =  224 bits (572), Expect = 1e-56
 Identities = 136/357 (38%), Positives = 195/357 (54%), Gaps = 47/357 (13%)

Query: 1200 FCEKCFNEIQGE-----SVSLGDDPSQ-----PQTTINKEQFSKR---KNDTLDPELFVE 1246
            FC  CF  I         V  G+D S         +  K ++ KR        + E +V+
Sbjct: 438  FCALCFKIINSTGSYYVEVENGNDKSSICGRCHHLSSAKAKYQKRFSYAETDAEAEWWVQ 497

Query: 1247 CTECGRKMHQICVLHH-EIIWP-AGFVCDGCLKKSARTRKENKFS------AKRLPSTRL 1298
            C +C    HQIC L + +I+ P A + C  C  K       +         A+ LP TRL
Sbjct: 498  CDKCKAWQHQICALFNPKIVDPEAEYTCAKCFLKEKDNEDVDSLEPSTILGARELPRTRL 557

Query: 1299 GTFLENRVNDFL---RRQNHPESGE----------VTVRVVHASDKTVEVKPGMKARFVD 1345
               +E R+++ L   R+Q    SG+          +TVRVV ++D+T++V+P  K  F  
Sbjct: 558  SDHIEQRLSERLVQERQQRAIASGKSVDEVPGVEGLTVRVVSSADRTLQVQPRFK-DFFK 616

Query: 1346 SGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFR 1405
              +    FPY++KA+  F++ +GVD+C F M+VQEYGS CP PNQR VY++Y+DSV +FR
Sbjct: 617  KEQYPGEFPYKSKAILLFQKNEGVDVCLFAMYVQEYGSACPSPNQRHVYLAYIDSVKYFR 676

Query: 1406 P-------KCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIP 1458
            P       + LRT VYHEILIGYL++ KK G+ +  IW CP ++ DDY+ +CHP  QK+P
Sbjct: 677  PEIKSASGEALRTFVYHEILIGYLDFCKKRGFVSCSIWTCPSTKRDDYVLYCHPTIQKMP 736

Query: 1459 KPKRLQEWYKKMLDKAVSERIV---HDYKDIFKQATEDRLT--SAKELPYFEGDFWP 1510
            K  +L+ WY+ ++ KAV E +V   +   D F Q T +  T  SA  LPY + DFWP
Sbjct: 737  KSDKLRSWYQNLVKKAVKEGVVVERNTLYDFFLQPTNECKTNISAAWLPYCDNDFWP 793



>gi|13486836|dbj|BAB40067.1| putative CREB-binding protein [Oryza sativa (japonica
            cultivar-group)]
          Length = 936

 Score =  224 bits (571), Expect = 1e-56
 Identities = 136/357 (38%), Positives = 195/357 (54%), Gaps = 47/357 (13%)

Query: 1200 FCEKCFNEIQGE-----SVSLGDDPSQ-----PQTTINKEQFSKR---KNDTLDPELFVE 1246
            FC  CF  I         V  G+D S         +  K ++ KR        + E +V+
Sbjct: 380  FCALCFKIINSTGSYYVEVENGNDKSSICGRCHHLSSAKAKYQKRFSYAETDAEAEWWVQ 439

Query: 1247 CTECGRKMHQICVLHH-EIIWP-AGFVCDGCLKKSARTRKENKFS------AKRLPSTRL 1298
            C +C    HQIC L + +I+ P A + C  C  K       +         A+ LP TRL
Sbjct: 440  CDKCKAWQHQICALFNPKIVDPEAEYTCAKCFLKEKDNEDVDSLEPSTILGARELPRTRL 499

Query: 1299 GTFLENRVNDFL---RRQNHPESGE----------VTVRVVHASDKTVEVKPGMKARFVD 1345
               +E R+++ L   R+Q    SG+          +TVRVV ++D+T++V+P  K  F  
Sbjct: 500  SDHIEQRLSERLVQERQQRAIASGKSVDEVPGVEGLTVRVVSSADRTLQVQPRFK-DFFK 558

Query: 1346 SGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFR 1405
              +    FPY++KA+  F++ +GVD+C F M+VQEYGS CP PNQR VY++Y+DSV +FR
Sbjct: 559  KEQYPGEFPYKSKAILLFQKNEGVDVCLFAMYVQEYGSACPSPNQRHVYLAYIDSVKYFR 618

Query: 1406 P-------KCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIP 1458
            P       + LRT VYHEILIGYL++ KK G+ +  IW CP ++ DDY+ +CHP  QK+P
Sbjct: 619  PEIKSASGEALRTFVYHEILIGYLDFCKKRGFVSCSIWTCPSTKRDDYVLYCHPTIQKMP 678

Query: 1459 KPKRLQEWYKKMLDKAVSERIV---HDYKDIFKQATEDRLT--SAKELPYFEGDFWP 1510
            K  +L+ WY+ ++ KAV E +V   +   D F Q T +  T  SA  LPY + DFWP
Sbjct: 679  KSDKLRSWYQNLVKKAVKEGVVVERNTLYDFFLQPTNECKTNISAAWLPYCDNDFWP 735



>gi|18405622|ref|NP_564706.1| CREB-binding protein -related [Arabidopsis thaliana]
          Length = 1456

 Score =  220 bits (561), Expect = 2e-55
 Identities = 143/388 (36%), Positives = 203/388 (52%), Gaps = 51/388 (13%)

Query: 1157 MQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSY---QNRYHFCEKCFNEIQGESV 1213
            + S   C    L F P  + C    +  I ++A +YS    ++R++ C  C+NE + + V
Sbjct: 721  VNSCQLCAVEWLVFEPVPIYCSPCGI-RIKKNALHYSIAVGESRHYVCAPCYNEAREKLV 779

Query: 1214 SLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVL------HHEIIWP 1267
             L        T+I K +  K+KND   PE +V+C +C    H IC L      H E    
Sbjct: 780  FLDG------TSIPKTRLQKKKNDEQVPEGWVQCDKCEAWQHIICALFNSRRNHGE---S 830

Query: 1268 AGFVCDGCLKKSARTRKENKF------SAKRLPSTRLGTFLENRVNDFLRRQNH------ 1315
              + C  C  +    R+           A  LP T L   LE R+   L+ +        
Sbjct: 831  TKYTCPSCYIQEVEQRERRPLPLSAVPGATSLPVTSLSKHLEERLFKKLKEERQERARLQ 890

Query: 1316 -------PESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDG 1368
                   P +  +TVRVV + DK +EVK      F +    +E FPY++KA+F F++I+ 
Sbjct: 891  GKTYEEVPGAESLTVRVVASVDKVLEVKERFLELFREENYPSE-FPYKSKAIFLFQKIEN 949

Query: 1369 VDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKL 1428
            V++C FGM VQE+G+D  PPN+RR + +          + LRT VYHEILIGYL+Y KK 
Sbjct: 950  VEVCLFGMFVQEFGTDSGPPNERRTFRT-------VSGEALRTFVYHEILIGYLDYCKKR 1002

Query: 1429 GYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHD----YK 1484
            G+T+ +IWACPP +GDDYI +CHP  QK PK  +L+EWY  ML KA  E +V +    Y 
Sbjct: 1003 GFTSCYIWACPPLKGDDYILYCHPEIQKTPKTDKLREWYLAMLRKASKEDVVVECTNLYN 1062

Query: 1485 DIFKQATEDRL-TSAKELPYFEGDFWPN 1511
              F Q+ E R   +A  LPYF+GD+WP+
Sbjct: 1063 HFFVQSGECRANVTAARLPYFDGDYWPS 1090




 Score =  119 bits (299), Expect = 6e-25
 Identities = 67/188 (35%), Positives = 100/188 (53%), Gaps = 11/188 (5%)

Query: 1627 RDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETR--WHCT 1684
            R AFL L +  + ++ +LRRA+ S+M +L  LH  +   F   C  C+  VE    WHC 
Sbjct: 1243 RQAFLNLCQGNNYQYETLRRAKHSSMMILYHLHNPTAPAFATVCTICQQEVENSQGWHCE 1302

Query: 1685 VCEDYDLCITCY--NTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSL 1742
            VC  YD+C  CY  ++ NH HK+       D     Q   A+Q    S ++ +++  + L
Sbjct: 1303 VCPGYDVCSACYSKDSINHSHKLTSRSSSTDSTVVQQNGQASQ----SYQVKLEKLKKLL 1358

Query: 1743 VHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCP 1802
            VHA  CR+  C    C+K K + +H   C   T G CPICK L +L   HA++C+++KC 
Sbjct: 1359 VHAATCRSTQCQYQGCRKSKMLFRHCIDC---TTGDCPICKGLWSLLKLHARNCRDSKCT 1415

Query: 1803 VPFCLNIK 1810
            VP C  ++
Sbjct: 1416 VPKCSGLR 1423



>gi|6056385|gb|AAF02849.1|AC009894_20 Unknown protein [Arabidopsis thaliana]
          Length = 1209

 Score =  194 bits (493), Expect = 2e-47
 Identities = 135/398 (33%), Positives = 192/398 (48%), Gaps = 80/398 (20%)

Query: 1157 MQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSY---QNRYHFCEKCFNEIQGESV 1213
            + S   C    L F P  + C    +  I ++A +YS    ++R++ C  C+NE + + V
Sbjct: 721  VNSCQLCAVEWLVFEPVPIYCSPCGI-RIKKNALHYSIAVGESRHYVCAPCYNEAREKLV 779

Query: 1214 SLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVL------HHEIIWP 1267
             L        T+I K +  K+KND   PE +V+C +C    H IC L      H E    
Sbjct: 780  FLDG------TSIPKTRLQKKKNDEQVPEGWVQCDKCEAWQHIICALFNSRRNHGE---S 830

Query: 1268 AGFVCDGCLKKSARTRKENKF------SAKRLPSTRLGTFLENR---------------- 1305
              + C  C  +    R+           A  LP T L   LE R                
Sbjct: 831  TKYTCPSCYIQEVEQRERRPLPLSAVPGATSLPVTSLSKHLEERLFKKLKEERQERARLQ 890

Query: 1306 -------VNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTK 1358
                   +++ LR    P +  +TVRVV + DK +EVK      F +    +E FPY++K
Sbjct: 891  GKTYEEVISNSLRLSTVPGAESLTVRVVASVDKVLEVKERFLELFREENYPSE-FPYKSK 949

Query: 1359 ALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEIL 1418
            A+F F++I+ V++C FGM VQE+G+D  PPN+RR                          
Sbjct: 950  AIFLFQKIENVEVCLFGMFVQEFGTDSGPPNERR-------------------------- 983

Query: 1419 IGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSER 1478
            IGYL+Y KK G+T+ +IWACPP +GDDYI +CHP  QK PK  +L+EWY  ML KA  E 
Sbjct: 984  IGYLDYCKKRGFTSCYIWACPPLKGDDYILYCHPEIQKTPKTDKLREWYLAMLRKASKED 1043

Query: 1479 IVHD----YKDIFKQATEDRL-TSAKELPYFEGDFWPN 1511
            +V +    Y   F Q+ E R   +A  LPYF+GD+WP+
Sbjct: 1044 VVVECTNLYNHFFVQSGECRANVTAARLPYFDGDYWPS 1081



>gi|20664269|pdb|1L3E|B Chain B, Nmr Structures Of The Hif-1alpha CtadP300 CH1 COMPLEX
 gi|33357860|pdb|1P4Q|B Chain B, Solution Structure Of The Cited2 Transactivation Domain In
           Complex With The P300 Ch1 Domain
          Length = 101

 Score =  191 bits (485), Expect = 1e-46
 Identities = 101/101 (100%), Positives = 101/101 (100%)

Query: 323 MGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHC 382
           MGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHC
Sbjct: 1   MGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHC 60

Query: 383 QSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDK 423
           QSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDK
Sbjct: 61  QSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDK 101



>gi|8778322|gb|AAF79331.1|AC002304_24 F14J16.27 [Arabidopsis thaliana]
          Length = 1550

 Score =  183 bits (464), Expect = 4e-44
 Identities = 143/456 (31%), Positives = 203/456 (44%), Gaps = 119/456 (26%)

Query: 1157 MQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSY---QNRYHFCEKCFNEIQGESV 1213
            + S   C    L F P  + C    +  I ++A +YS    ++R++ C  C+NE + + V
Sbjct: 721  VNSCQLCAVEWLVFEPVPIYCSPCGI-RIKKNALHYSIAVGESRHYVCAPCYNEAREKLV 779

Query: 1214 SLGDDPSQPQTTINKEQFSKRKNDTLDPE------------------------------- 1242
             L        T+I K +  K+KND   PE                               
Sbjct: 780  FLDG------TSIPKTRLQKKKNDEQVPEGVCMPHDFGNLFLPLFFFFFVFFFCVCLNQT 833

Query: 1243 ----LFVECTECGRKMHQICVL------HHEIIWPAGFVCDGCLKKSARTRKENKF---- 1288
                 +V+C +C    H IC L      H E      + C  C  +    R+        
Sbjct: 834  NGFLQWVQCDKCEAWQHIICALFNSRRNHGE---STKYTCPSCYIQEVEQRERRPLPLSA 890

Query: 1289 --SAKRLPSTRLGTFLENRVNDFLRRQNH-------------PESGEVTVRVVHASDKTV 1333
               A  LP T L   LE R+   L+ +               P +  +TVRVV + DK +
Sbjct: 891  VPGATSLPVTSLSKHLEERLFKKLKEERQERARLQGKTYEEVPGAESLTVRVVASVDKVL 950

Query: 1334 EVKPGMKARFVDSGEMAESFPYRTK---ALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQ 1390
            EVK      F +    +E FPY++K   A+F F++I+ V++C FGM VQE+G+D  PPN+
Sbjct: 951  EVKERFLELFREENYPSE-FPYKSKVAMAIFLFQKIENVEVCLFGMFVQEFGTDSGPPNE 1009

Query: 1391 RRVYISYLDSVHFFRPKCLRTAVYHEIL------------------------------IG 1420
            RR + +          + LRT VYHEIL                              IG
Sbjct: 1010 RRTFRT-------VSGEALRTFVYHEILVSRFISNPIFFRFRVLLHEYMKLIIVTNLQIG 1062

Query: 1421 YLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIV 1480
            YL+Y KK G+T+ +IWACPP +GDDYI +CHP  QK PK  +L+EWY  ML KA  E +V
Sbjct: 1063 YLDYCKKRGFTSCYIWACPPLKGDDYILYCHPEIQKTPKTDKLREWYLAMLRKASKEDVV 1122

Query: 1481 HD----YKDIFKQATEDRL-TSAKELPYFEGDFWPN 1511
             +    Y   F Q+ E R   +A  LPYF+GD+WP+
Sbjct: 1123 VECTNLYNHFFVQSGECRANVTAARLPYFDGDYWPS 1158




 Score =  120 bits (300), Expect = 4e-25
 Identities = 67/188 (35%), Positives = 100/188 (53%), Gaps = 11/188 (5%)

Query: 1627 RDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETR--WHCT 1684
            R AFL L +  + ++ +LRRA+ S+M +L  LH  +   F   C  C+  VE    WHC 
Sbjct: 1337 RQAFLNLCQGNNYQYETLRRAKHSSMMILYHLHNPTAPAFATVCTICQQEVENSQGWHCE 1396

Query: 1685 VCEDYDLCITCY--NTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSL 1742
            VC  YD+C  CY  ++ NH HK+       D     Q   A+Q    S ++ +++  + L
Sbjct: 1397 VCPGYDVCSACYSKDSINHSHKLTSRSSSTDSTVVQQNGQASQ----SYQVKLEKLKKLL 1452

Query: 1743 VHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCP 1802
            VHA  CR+  C    C+K K + +H   C   T G CPICK L +L   HA++C+++KC 
Sbjct: 1453 VHAATCRSTQCQYQGCRKSKMLFRHCIDC---TTGDCPICKGLWSLLKLHARNCRDSKCT 1509

Query: 1803 VPFCLNIK 1810
            VP C  ++
Sbjct: 1510 VPKCSGLR 1517



>gi|11514507|pdb|1F81|A Chain A, Solution Structure Of The Taz2 Domain Of The Transcriptional
            Adaptor Protein Cbp
          Length = 88

 Score =  177 bits (450), Expect = 2e-42
 Identities = 82/85 (96%), Positives = 84/85 (98%)

Query: 1726 SPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQL 1785
            SP +SRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCP+CKQL
Sbjct: 2    SPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQL 61

Query: 1786 IALCCYHAKHCQENKCPVPFCLNIK 1810
            IALCCYHAKHCQENKCPVPFCLNIK
Sbjct: 62   IALCCYHAKHCQENKCPVPFCLNIK 86




 Score = 40.0 bits (92), Expect = 0.60
 Identities = 32/94 (34%), Positives = 50/94 (53%), Gaps = 18/94 (19%)

Query: 333 EKRKL-IQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVA 391
           E R+L IQ+ +  L+HA +C+    AN     C+LP C+ MK V+ H   C+   +    
Sbjct: 5   ESRRLSIQRCIQSLVHACQCR---NAN-----CSLPSCQKMKRVVQHTKGCKRKTN---G 53

Query: 392 HCASSRQIIS----HWKNCTRHDCPV--CLPLKN 419
            C   +Q+I+    H K+C  + CPV  CL +K+
Sbjct: 54  GCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKH 87



>gi|20664319|pdb|1L8C|A Chain A, Structural Basis For Hif-1alphaCBP RECOGNITION IN THE
           Cellular Hypoxic Response
          Length = 95

 Score =  173 bits (438), Expect = 4e-41
 Identities = 90/95 (94%), Positives = 93/95 (97%)

Query: 330 ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQ 389
           ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+GK+CQ
Sbjct: 1   ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQ 60

Query: 390 VAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKR 424
           VAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKR
Sbjct: 61  VAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKR 95



>gi|4139873|pdb|1KDX|A Chain A, Kix Domain Of Mouse Cbp (Creb Binding Protein) In Complex
           With Phosphorylated Kinase Inducible Domain (Pkid) Of
           Rat Creb (Cyclic Amp Response Element Binding Protein),
           Nmr 17 Structures
          Length = 81

 Score =  159 bits (402), Expect = 6e-37
 Identities = 72/80 (90%), Positives = 77/80 (96%)

Query: 567 IRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNR 626
           +RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGDMYESAN+R
Sbjct: 2   VRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSR 61

Query: 627 AEYYHLLAEKIYKIQKELEE 646
            EYYHLLAEKIYKIQKELEE
Sbjct: 62  DEYYHLLAEKIYKIQKELEE 81



>gi|19173734|ref|NP_596872.1| CREB binding protein; Creb binding protein (CBP) [Rattus
           norvegicus]
 gi|15076624|dbj|BAB62424.1| CREB-binding protein [Rattus norvegicus]
          Length = 351

 Score =  143 bits (361), Expect = 3e-32
 Identities = 136/370 (36%), Positives = 183/370 (49%), Gaps = 53/370 (14%)

Query: 1   MAENVVEPGPPSAKRPKXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
           MAEN+++ GPP+ KR K           D TDFGSLFDLE+DLPDELI + EL L N G+
Sbjct: 1   MAENLLD-GPPNPKRAK--LSSPGFSANDSTDFGSLFDLENDLPDELIPNGELSLLNSGN 57

Query: 61  INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGG--------PGQVMASQAQQSS 112
                    +V DAASKHKQLSELLR GS  ++  G+G          G    +Q Q +S
Sbjct: 58  ---------LVPDAASKHKQLSELLRGGSGSSITPGIGNVSASSPVQQGLGGQAQGQPNS 108

Query: 113 PGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQP 161
             +  + +M KSP+     ++P++      TSGP    +Q+         G++ S     
Sbjct: 109 TSMASLGAMGKSPLNPGDSSTPSLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATS 168

Query: 162 AMGMNTGTNAGMN---PGMLAAGNGQGIMPN------QVMNGSI--GAGRGRQDMQYPNP 210
             G     NA  N   PG+L + +G  +M        QVMNGS+          M YP P
Sbjct: 169 QTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLGAAGRGRGAGMPYPAP 228

Query: 211 GM-GSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQIG 266
            M G+  ++L E L Q SPQM G  GL   Q     KMGM  N +P+G P++Q  GQ +G
Sbjct: 229 AMQGATSSVLAETLTQVSPQMAGHAGLNTAQAGGMTKMGMTGNTSPFGQPFSQTGGQPMG 288

Query: 267 ASGLGLQIQTKTVLSNNLSPFAMDKKAVXXXXXXXXXXXXXXXXXXXGLVTPVAQGMGSG 326
           A+G+  Q+ +K  + N+L  F  D K                     G+V   AQG+ +G
Sbjct: 289 ATGVNPQLASKQSMVNSLPAFPTDIKNT----SVTTVPNMSQLQTSVGIVP--AQGIATG 342

Query: 327 AHTADPEKRK 336
             TADPEKRK
Sbjct: 343 P-TADPEKRK 351



>gi|17553334|ref|NP_499197.1| CREB-binding protein like family member (22.2 kD) (3L5)
           [Caenorhabditis elegans]
 gi|542476|pir||S42836 F40F12.7 protein - Caenorhabditis elegans
 gi|3877001|emb|CAA82938.1| Hypothetical protein F40F12.7 [Caenorhabditis elegans]
          Length = 199

 Score =  130 bits (327), Expect = 3e-28
 Identities = 63/101 (62%), Positives = 70/101 (69%), Gaps = 9/101 (8%)

Query: 331 DPEKRKLIQQQLVLLLHAHKCQRREQANGEV---------RQCNLPHCRTMKNVLNHMTH 381
           DP KRKLIQQQ VLLLHAHKC +RE+ N E            C LPHC TMK VL HMT+
Sbjct: 7   DPVKRKLIQQQFVLLLHAHKCSQREKENNEFAARNQLLPHAACTLPHCSTMKEVLIHMTN 66

Query: 382 CQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGD 422
           C  G+ C  AHCASSRQII+HWK+C+R DCPVC PLK   D
Sbjct: 67  CNVGRLCHFAHCASSRQIIAHWKDCSREDCPVCKPLKGIQD 107



>gi|9368432|emb|CAB98139.1| MOZ/CBP protein [Homo sapiens]
          Length = 376

 Score =  128 bits (322), Expect = 1e-27
 Identities = 115/316 (36%), Positives = 160/316 (50%), Gaps = 44/316 (13%)

Query: 12  SAKRPKXXXXXXXXXXXDGTDFGSLFDLEHDLPDELI-NSTELGLTNGGDINQLQTSLGM 70
           S+ + K           D  DFGSLFDLE+DLPDELI N  ELGL N G+         +
Sbjct: 43  SSSKRKSKDEEEDEESDDADDFGSLFDLENDLPDELIPNGGELGLLNSGN---------L 93

Query: 71  VQDAASKHKQLSELLRSGSSPNLNMGVGG--------PGQVMASQAQQSSPGLGLINSMV 122
           V DAASKHKQLSELLR GS  ++N G+G          G    +Q Q +S  +  +++M 
Sbjct: 94  VPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMG 153

Query: 123 KSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQPAMGMNTGTNA 171
           KSP++Q   ++P++      TSGP    +Q+         G+  S       G     NA
Sbjct: 154 KSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNA 213

Query: 172 GMN---PGMLAAGNGQGIMPN------QVMNGSI--GAGRGRQDMQYPNPGM-GSAGNLL 219
             N   PG+L + +G  ++        QVMNGS+          M YP P M G++ ++L
Sbjct: 214 NFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVL 273

Query: 220 TEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQT 276
            E L Q SPQM G  GL   Q     KMG+  N +P+G P++Q  GQ +GA+G+  Q+ +
Sbjct: 274 AETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLAS 333

Query: 277 KTVLSNNLSPFAMDKK 292
           K  + N+L  F  D K
Sbjct: 334 KQSMVNSLPTFPTDIK 349



>gi|14794966|gb|AAK73519.1| HAC4 [Arabidopsis thaliana]
          Length = 413

 Score =  123 bits (308), Expect = 5e-26
 Identities = 67/188 (35%), Positives = 100/188 (53%), Gaps = 11/188 (5%)

Query: 1627 RDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETR--WHCT 1684
            R AFL L +  + ++ +LRRA+ S+M +L  LH  +   F   C  C+  VE    WHC 
Sbjct: 200  RQAFLNLCQGNNYQYETLRRAKHSSMMILYHLHNPTAPAFATVCTICQQEVENSQGWHCE 259

Query: 1685 VCEDYDLCITCY--NTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSL 1742
            VC  YD+C  CY  ++ NH HK+       D     Q   A+Q    S ++ +++  + L
Sbjct: 260  VCPGYDVCSACYSKDSINHSHKLTSRSSSTDSTVVQQNGQASQ----SYQVKLEKLKKLL 315

Query: 1743 VHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCP 1802
            VHA  CR+  C    C+K K + +H   C   T G CPICK L +L   HA++C+++KC 
Sbjct: 316  VHAATCRSTQCQYQGCRKSKMLFRHCIDC---TTGDCPICKGLWSLLKLHARNCRDSKCT 372

Query: 1803 VPFCLNIK 1810
            VP C  ++
Sbjct: 373  VPKCSGLR 380



>gi|21105785|gb|AAM34790.1|AF512560_2 HAC4 [Arabidopsis thaliana]
          Length = 385

 Score =  122 bits (306), Expect = 9e-26
 Identities = 67/188 (35%), Positives = 100/188 (53%), Gaps = 11/188 (5%)

Query: 1627 RDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETR--WHCT 1684
            R AFL L +  + ++ +LRRA+ S+M +L  LH  +   F   C  C+  VE    WHC 
Sbjct: 172  RQAFLNLCQGNNYQYETLRRAKHSSMMILYHLHNPTAPAFATVCTICQQEVENSQGWHCE 231

Query: 1685 VCEDYDLCITCY--NTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSL 1742
            VC  YD+C  CY  ++ NH HK+       D     Q   A+Q    S ++ +++  + L
Sbjct: 232  VCPGYDVCSACYSKDSINHSHKLTSRSSSTDSTVVQQNGQASQ----SYQVKLEKLKKLL 287

Query: 1743 VHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCP 1802
            VHA  CR+  C    C+K K + +H   C   T G CPICK L +L   HA++C+++KC 
Sbjct: 288  VHAATCRSTQCQYQGCRKSKMLFRHCIDC---TTGDCPICKGLWSLLKLHARNCRDSKCT 344

Query: 1803 VPFCLNIK 1810
            VP C  ++
Sbjct: 345  VPKCSGLR 352



>gi|7494646|pir||T37269 hypothetical protein - Caenorhabditis elegans (fragment)
 gi|2665395|dbj|BAA23766.1| unnamed protein product [Caenorhabditis elegans]
          Length = 118

 Score =  112 bits (280), Expect = 9e-23
 Identities = 65/101 (64%), Positives = 71/101 (70%), Gaps = 9/101 (8%)

Query: 331 DPEKRKLIQQQLVLLLHAHKCQRREQANGEV---------RQCNLPHCRTMKNVLNHMTH 381
           DPEKRKLIQQQLVLLLHAHKC +RE+ N +            C LPHC TMK VL HMT 
Sbjct: 3   DPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTS 62

Query: 382 CQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGD 422
           C  G+ C  AHCASSRQII+HWKNC+R DCPVC PLK   D
Sbjct: 63  CNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCKPLKRIQD 103



>gi|482238|pir||S41033 hypothetical protein K03H1.10 - Caenorhabditis elegans  (fragment)
          Length = 316

 Score =  108 bits (270), Expect = 1e-21
 Identities = 63/101 (62%), Positives = 71/101 (70%), Gaps = 9/101 (8%)

Query: 331 DPEKRKLIQQQLVLLLHAHKCQRREQANGEV---------RQCNLPHCRTMKNVLNHMTH 381
           DP K+KL+QQQLVLLLHAHKC  R++ N E            C LPHC TMK VL HMT+
Sbjct: 1   DPVKQKLVQQQLVLLLHAHKCSLRDKENNEFAARNQPLPHTTCRLPHCPTMKEVLIHMTN 60

Query: 382 CQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGD 422
           C  G+ C  AHCASSRQII+HWKNC+R DCPVC PLK A D
Sbjct: 61  CNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCTPLKRARD 101




 Score =  101 bits (252), Expect = 2e-19
 Identities = 53/108 (49%), Positives = 76/108 (70%), Gaps = 8/108 (7%)

Query: 547 NASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRME 606
           N ++ +L P      P+     K+WH  +T DLRNH+V KLV+AI P P+   + D R++
Sbjct: 145 NGNISNLPP------PNVPVRTKEWHRQVTNDLRNHIVGKLVKAICPAPE--MMNDIRLK 196

Query: 607 NLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQK 654
           +L AYARKVE +++E+A +R  YYHLLAEKIY+IQKEL+EK+ +RL +
Sbjct: 197 DLNAYARKVEKEVFETAIDRKNYYHLLAEKIYEIQKELQEKKNSRLNQ 244





  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF
    Posted date:  Sep 11, 2003  1:15 AM
  Number of letters in database: 490,308,901
  Number of sequences in database:  1,522,899
  
Lambda     K      H
   0.316    0.132    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 189,574,954
Number of Sequences: 1522899
Number of extensions: 7665832
Number of successful extensions: 20577
Number of sequences better than  1.0: 80
Number of HSP's better than  1.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 20074
Number of HSP's gapped (non-prelim): 355
length of query: 2414
length of database: 490,308,901
effective HSP length: 141
effective length of query: 2273
effective length of database: 275,580,142
effective search space: 626393662766
effective search space used: 626393662766
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 90 (39.3 bits)