>gi|547239|gb|AAB31182.1| p300=transcription coactivator {N-terminal} [mice, Peptide Partial,
688 aa]
Length = 688
Score = 1018 bits (2633), Expect = 0.0
Identities = 594/688 (86%), Positives = 594/688 (86%)
Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
MAENVVEPGPP DGTDFGSLFDLEHDLPDELINSTELGLTNGGD
Sbjct: 1 MAENVVEPGPPSAKRLKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQACQNSPGLSLINS 120
SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQACQNSPGLSLINS
Sbjct: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQACQNSPGLSLINS 120
Query: 121 MVKSPMACTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQXXXXXXXXXXXXXXXXXLA 180
MVKSPMACTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQ LA
Sbjct: 121 MVKSPMACTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQPAMGMNTGMNAGMNPGMLA 180
Query: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEXXXXXXXXXXXXXXXXXX 240
AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTE
Sbjct: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEPLQQGSPQMGGQPGLRGP 240
Query: 241 XXLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXX 300
LKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAV
Sbjct: 241 QPLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVPGGGM 300
Query: 301 XXXXXXXXXSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANG 360
SVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANG
Sbjct: 301 PSMGQQPTPSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANG 360
Query: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420
EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN
Sbjct: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420
Query: 421 AGDKRNQCSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXX 480
AGDKRNQCSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGL
Sbjct: 421 AGDKRNQCSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQ 480
Query: 481 XXXXXXXXAKNXXXXXXXXXXXXMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS 540
AKN MRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS
Sbjct: 481 IPPQPQVQAKNQQSQPSGQSPQGMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS 540
Query: 541 QNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 600
QNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA
Sbjct: 541 QNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 600
Query: 601 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660
LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP
Sbjct: 601 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660
Query: 661 NAPGMGPVPMNTGSNMGQQPTGMTTNGP 688
NAPGMGPVPMNTGSNMGQQPTGMTTNGP
Sbjct: 661 NAPGMGPVPMNTGSNMGQQPTGMTTNGP 688
>gi|28486616|ref|XP_283295.1| similar to E1A-associated protein p300 [Mus musculus]
gi|29244384|ref|NP_808489.1| hypothetical protein A730011L11 [Mus musculus]
gi|26335221|dbj|BAC31311.1| unnamed protein product [Mus musculus]
Length = 714
Score = 974 bits (2517), Expect = 0.0
Identities = 587/688 (85%), Positives = 588/688 (85%)
Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
MAENVVEPGPP DGTDFGSLFDLEHDLPDELINSTELGLTNGGD
Sbjct: 1 MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQACQNSPGLSLINS 120
SQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQA QNSPGLSLINS
Sbjct: 61 ISQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQAQQNSPGLSLINS 120
Query: 121 MVKSPMACTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQXXXXXXXXXXXXXXXXXLA 180
MVKSPMA TGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQ LA
Sbjct: 121 MVKSPMAQTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQPAMGMNTGMNAGMNPGMLA 180
Query: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEXXXXXXXXXXXXXXXXXX 240
AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTE
Sbjct: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEPLQQGSPQMGGQPGLRGP 240
Query: 241 XXLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXX 300
LKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAV
Sbjct: 241 QPLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVPGGGM 300
Query: 301 XXXXXXXXXSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANG 360
SVQQPGLVTPVAAGMGSGAHTADPEKR +IQQQLVLLLHAHKCQRREQANG
Sbjct: 301 PSMGQQPTPSVQQPGLVTPVAAGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANG 360
Query: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420
EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN
Sbjct: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420
Query: 421 AGDKRNQCSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXX 480
AGDKRNQ SILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGL
Sbjct: 421 AGDKRNQQSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQ 480
Query: 481 XXXXXXXXAKNXXXXXXXXXXXXMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS 540
AKN MRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS
Sbjct: 481 IPPQPQVQAKNQQSQPSGQSPQGMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS 540
Query: 541 QNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 600
QNPMMS NAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA
Sbjct: 541 QNPMMSENAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 600
Query: 601 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660
LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP
Sbjct: 601 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660
Query: 661 NAPGMGPVPMNTGSNMGQQPTGMTTNGP 688
NAPGMGPVPMNTGSNMGQQPTGMTTNGP
Sbjct: 661 NAPGMGPVPMNTGSNMGQQPTGMTTNGP 688
>gi|31753089|gb|AAH53889.1| Unknown (protein for IMAGE:6151364) [Homo sapiens]
Length = 1553
Score = 959 bits (2480), Expect = 0.0
Identities = 546/688 (79%), Positives = 562/688 (81%), Gaps = 1/688 (0%)
Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
MAENVVEPGPP DGTDFGSLFDLEHDLPDELINSTELGLTNGGD
Sbjct: 1 MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQACQNSPGLSLINS 120
+QLQTSLG+VQDAASKHKQLSELLRSGSSPNLNMGVGGPGQ MASQA Q+SPGL LINS
Sbjct: 61 INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS 120
Query: 121 MVKSPMACTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQXXXXXXXXXXXXXXXXXLA 180
MVKSPM GLTSPNMG+G+SGPNQGPTQS GMMNSPVNQ LA
Sbjct: 121 MVKSPMTQAGLTSPNMGMGTSGPNQGPTQS-TGMMNSPVNQPAMGMNTGMNAGMNPGMLA 179
Query: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEXXXXXXXXXXXXXXXXXX 240
AGNGQGIMPNQVMNGSIGAGRGR NMQYPN GMG+AG+LLTE
Sbjct: 180 AGNGQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGP 239
Query: 241 XXLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXX 300
LKMGMMNNP+PYGSPYTQN GQQIGASGLGLQIQTKTVL NNLSPFAMDKKAV
Sbjct: 240 QPLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGM 299
Query: 301 XXXXXXXXXSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANG 360
VQQPGLVTPVA GMGSGAHTADPEKR +IQQQLVLLLHAHKCQRREQANG
Sbjct: 300 PNMGQQPAPQVQQPGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANG 359
Query: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420
EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN
Sbjct: 360 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 419
Query: 421 AGDKRNQCSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXX 480
AGDKRNQ ILTGAPVGLGNPSSLGVGQQS P+LSTVSQIDPSSIERAYAALGL
Sbjct: 420 AGDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQ 479
Query: 481 XXXXXXXXAKNXXXXXXXXXXXXMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS 540
AKN MR ++NMSASPMGVNGGVGVQTP+LLSDSMLHS INS
Sbjct: 480 MPTQPQVQAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINS 539
Query: 541 QNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 600
QNPMMS NA V SLGP+PTAAQPS+TGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA
Sbjct: 540 QNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 599
Query: 601 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660
LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP
Sbjct: 600 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 659
Query: 661 NAPGMGPVPMNTGSNMGQQPTGMTTNGP 688
NA GM PV MN G NMGQ GMT+NGP
Sbjct: 660 NAAGMVPVSMNPGPNMGQPQPGMTSNGP 687
>gi|4557557|ref|NP_001420.1| E1A binding protein p300; E1A-binding protein, 300kD [Homo sapiens]
gi|3024341|sp|Q09472|P300_HUMAN E1A-associated protein p300
gi|627657|pir||A54277 transcription adaptor protein p300 - human
gi|495301|gb|AAA18639.1| p300 protein
Length = 2414
Score = 942 bits (2435), Expect = 0.0
Identities = 545/688 (79%), Positives = 562/688 (81%), Gaps = 1/688 (0%)
Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
MAENVVEPGPP DGTDFGSLFDLEHDLPDELINSTELGLTNGGD
Sbjct: 1 MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQACQNSPGLSLINS 120
+QLQTSLG+VQDAASKHKQLSELLRSGSSPNLNMGVGGPGQ MASQA Q+SPGL LINS
Sbjct: 61 INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS 120
Query: 121 MVKSPMACTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQXXXXXXXXXXXXXXXXXLA 180
MVKSPM GLTSPNMG+G+SGPNQGPTQS GMMNSPVNQ LA
Sbjct: 121 MVKSPMTQAGLTSPNMGMGTSGPNQGPTQS-TGMMNSPVNQPAMGMNTGTNAGMNPGMLA 179
Query: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEXXXXXXXXXXXXXXXXXX 240
AGNGQGIMPNQVMNGSIGAGRGR +MQYPN GMG+AG+LLTE
Sbjct: 180 AGNGQGIMPNQVMNGSIGAGRGRQDMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGP 239
Query: 241 XXLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXX 300
LKMGMMNNP+PYGSPYTQN GQQIGASGLGLQIQTKTVL NNLSPFAMDKKAV
Sbjct: 240 QPLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGM 299
Query: 301 XXXXXXXXXSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANG 360
VQQPGLVTPVA GMGSGAHTADPEKR +IQQQLVLLLHAHKCQRREQANG
Sbjct: 300 PNMGQQPAPQVQQPGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANG 359
Query: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420
EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN
Sbjct: 360 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 419
Query: 421 AGDKRNQCSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXX 480
AGDKRNQ ILTGAPVGLGNPSSLGVGQQS P+LSTVSQIDPSSIERAYAALGL
Sbjct: 420 AGDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQ 479
Query: 481 XXXXXXXXAKNXXXXXXXXXXXXMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS 540
AKN MR ++NMSASPMGVNGGVGVQTP+LLSDSMLHS INS
Sbjct: 480 MPTQPQVQAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINS 539
Query: 541 QNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 600
QNPMMS NA V SLGP+PTAAQPS+TGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA
Sbjct: 540 QNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 599
Query: 601 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660
LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP
Sbjct: 600 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 659
Query: 661 NAPGMGPVPMNTGSNMGQQPTGMTTNGP 688
NA GM PV MN G NMGQ GMT+NGP
Sbjct: 660 NAAGMVPVSMNPGPNMGQPQPGMTSNGP 687
>gi|27666550|ref|XP_235770.1| similar to E1A-associated protein p300 [Rattus norvegicus]
Length = 1605
Score = 532 bits (1371), Expect = e-150
Identities = 278/313 (88%), Positives = 281/313 (89%)
Query: 373 MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILT 432
MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQ SILT
Sbjct: 1 MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQSILT 60
Query: 433 GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNX 492
GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGL AKN
Sbjct: 61 GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQIPPQPPVQAKNQ 120
Query: 493 XXXXXXXXXXXMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMMSGNAGVA 552
MRS+NNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMM+ NA VA
Sbjct: 121 QSQPSGQSPQGMRSMNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMMNENASVA 180
Query: 553 SLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY 612
SLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY
Sbjct: 181 SLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY 240
Query: 613 ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGMGPVPMNT 672
ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP+APGM PVPMNT
Sbjct: 241 ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPSAPGMVPVPMNT 300
Query: 673 GSNMGQQPTGMTT 685
NMGQQPTGMTT
Sbjct: 301 APNMGQQPTGMTT 313
Score = 37.7 bits (86), Expect = 0.65
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 15/84 (17%)
Query: 335 KRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHC 394
+R IQ+ + L+HA +C+ AN C+LP C+ MK V+ H C+ + C
Sbjct: 1202 RRLSIQRCIQSLVHACQCR---NAN-----CSLPSCQKMKRVVQHTKGCKRKTN---GGC 1250
Query: 395 ASSRQIIS----HWKNCTRHDCPV 414
+Q+I+ H K+C + CPV
Sbjct: 1251 PICKQLIALCCYHAKHCQENKCPV 1274
>gi|27663074|ref|XP_235502.1| similar to E1A-associated protein p300 [Rattus norvegicus]
Length = 2156
Score = 517 bits (1331), Expect = e-145
Identities = 278/313 (88%), Positives = 281/313 (89%)
Query: 373 MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILT 432
MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQ SILT
Sbjct: 1 MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQSILT 60
Query: 433 GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNX 492
GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGL AKN
Sbjct: 61 GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQIPPQPPVQAKNQ 120
Query: 493 XXXXXXXXXXXMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMMSGNAGVA 552
MRS+NNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMM+ NA VA
Sbjct: 121 QSQPSGQSPQGMRSMNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMMNENASVA 180
Query: 553 SLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY 612
SLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY
Sbjct: 181 SLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY 240
Query: 613 ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGMGPVPMNT 672
ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP+APGM PVPMNT
Sbjct: 241 ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPSAPGMVPVPMNT 300
Query: 673 GSNMGQQPTGMTT 685
NMGQQPTGMTT
Sbjct: 301 APNMGQQPTGMTT 313
>gi|4758056|ref|NP_004371.1| CREB binding protein [Homo sapiens]
gi|3023440|sp|Q92793|CBP_HUMAN CREB-binding protein
gi|2443859|gb|AAC51770.1| CREB-binding protein
Length = 2442
Score = 474 bits (1220), Expect = e-132
Identities = 340/735 (46%), Positives = 418/735 (56%), Gaps = 75/735 (10%)
Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG 59
MAEN+++ GPP D TDFGSLFDLE+DLPDELI N ELGL N G
Sbjct: 1 MAENLLD-GPP--NPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSG 57
Query: 60 DSSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQA--------MASQACQN 111
+ +V DAASKHKQLSELLR GS ++N G+G + +Q N
Sbjct: 58 N---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN 108
Query: 112 SPGLSLINSMVKSPMACTGLTSPNM---GIGSSGPNQGPTQS------------------ 150
S ++ +++M KSP++ ++P++ +SGP +Q+
Sbjct: 109 SANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT 168
Query: 151 ----PAGMMNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSI--GAGRGRP 204
P MN+ NQ + G QVMNGS+
Sbjct: 169 SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQA------QVMNGSLGAAGRGRGA 222
Query: 205 NMQYPNAGM-GNAGSLLTE---XXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQ 260
M YP M G + S+L E KMG+ N SP+G P++Q
Sbjct: 223 GMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQ 282
Query: 261 NSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPV 320
GQ +GA+G+ Q+ +K + N+L F D K G+V
Sbjct: 283 AGGQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQ----TSVGIVPTQ 338
Query: 321 AAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHM 380
A G TADPEKR +IQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHM
Sbjct: 339 AIATGP---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHM 395
Query: 381 THCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGN 440
THCQ+GK+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQ +IL G+ N
Sbjct: 396 THCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQN 455
Query: 441 P-SSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNXXXXXXXX 499
S+G GQQ+ SLS + IDPSS++RAYAALGL
Sbjct: 456 TIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQ--QPAQPQ 513
Query: 500 XXXXMRSVNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINSQNPMM---SGNAGVAS 553
MR++N + +PM + G Q PNL+S+S L +++ + NP+M S + + +
Sbjct: 514 THQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGT 573
Query: 554 LGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYA 613
L +PTAA PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA
Sbjct: 574 LSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYA 633
Query: 614 RKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGMGPVPMNTG 673
+KVEGDMYESAN+R EYYHLLAEKIYKIQKELEEKRR+RL KQ +L N P + P P
Sbjct: 634 KKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPAL-PAPGAQP 692
Query: 674 SNMGQQPTGMTTNGP 688
+ Q NGP
Sbjct: 693 PVIPQAQPVRPPNGP 707
>gi|4321116|gb|AAC51331.2| CREB-binding protein [Homo sapiens]
Length = 2442
Score = 474 bits (1220), Expect = e-132
Identities = 340/735 (46%), Positives = 418/735 (56%), Gaps = 75/735 (10%)
Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG 59
MAEN+++ GPP D TDFGSLFDLE+DLPDELI N ELGL N G
Sbjct: 1 MAENLLD-GPP--NPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSG 57
Query: 60 DSSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQA--------MASQACQN 111
+ +V DAASKHKQLSELLR GS ++N G+G + +Q N
Sbjct: 58 N---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN 108
Query: 112 SPGLSLINSMVKSPMACTGLTSPNM---GIGSSGPNQGPTQS------------------ 150
S ++ +++M KSP++ ++P++ +SGP +Q+
Sbjct: 109 SANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT 168
Query: 151 ----PAGMMNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSI--GAGRGRP 204
P MN+ NQ + G QVMNGS+
Sbjct: 169 SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQA------QVMNGSLGAAGRGRGA 222
Query: 205 NMQYPNAGM-GNAGSLLTE---XXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQ 260
M YP M G + S+L E KMG+ N SP+G P++Q
Sbjct: 223 GMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQ 282
Query: 261 NSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPV 320
GQ +GA+G+ Q+ +K + N+L F D K G+V
Sbjct: 283 AGGQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQ----TSVGIVPTQ 338
Query: 321 AAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHM 380
A G TADPEKR +IQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHM
Sbjct: 339 AIATGP---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHM 395
Query: 381 THCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGN 440
THCQ+GK+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQ +IL G+ N
Sbjct: 396 THCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQN 455
Query: 441 P-SSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNXXXXXXXX 499
S+G GQQ+ SLS + IDPSS++RAYAALGL
Sbjct: 456 TIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQ--QPAQPQ 513
Query: 500 XXXXMRSVNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINSQNPMM---SGNAGVAS 553
MR++N + +PM + G Q PNL+S+S L +++ + NP+M S + + +
Sbjct: 514 THQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGT 573
Query: 554 LGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYA 613
L +PTAA PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA
Sbjct: 574 LSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYA 633
Query: 614 RKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGMGPVPMNTG 673
+KVEGDMYESAN+R EYYHLLAEKIYKIQKELEEKRR+RL KQ +L N P + P P
Sbjct: 634 KKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPAL-PAPGAQP 692
Query: 674 SNMGQQPTGMTTNGP 688
+ Q NGP
Sbjct: 693 PVIPQAQPVRPPNGP 707
>gi|1345703|sp|P45481|CBP_MOUSE CREB-binding protein
gi|481698|pir||S39161 CREB-binding protein - mouse
gi|435855|gb|AAB28651.1| CREB-binding protein; CBP [Mus sp.]
Length = 2441
Score = 473 bits (1216), Expect = e-132
Identities = 336/711 (47%), Positives = 405/711 (56%), Gaps = 73/711 (10%)
Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
MAEN+++ GPP D TDFGSLFDLE+DLPDELI + EL L N G+
Sbjct: 1 MAENLLD-GPP--NPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIPNGELSLLNSGN 57
Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQA--------MASQACQNS 112
+V DAASKHKQLSELLR GS ++N G+G + +Q NS
Sbjct: 58 ---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNS 108
Query: 113 PGLSLINSMVKSPMACTGLTSPNM---GIGSSGPNQGPTQS------------------- 150
++ + +M KSP+ ++PN+ +SGP +Q+
Sbjct: 109 TNMASLGAMGKSPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATS 168
Query: 151 ---PAGMMNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSI--GAGRGRPN 205
P MN+ NQ G QVMNGS+
Sbjct: 169 QTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQA------QVMNGSLGAAGRGRGAG 222
Query: 206 MQYPNAGM-GNAGSLLTE---XXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQN 261
M YP M G S+L E KMGM SP+G P++Q
Sbjct: 223 MPYPAPAMQGATSSVLAETLTQVSPQMAGHAGLNTAQAGGMTKMGMTGTTSPFGQPFSQT 282
Query: 262 SGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPVA 321
GQQ+GA+G+ Q+ +K + N+L F D K G+V A
Sbjct: 283 GGQQMGATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMSQLQ----TSVGIVPTQA 338
Query: 322 AGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMT 381
G TADPEKR +IQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMT
Sbjct: 339 IATGP---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMT 395
Query: 382 HCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGNP 441
HCQ+ K+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQ +IL G+ N
Sbjct: 396 HCQAPKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNT 455
Query: 442 -SSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNXXXXXXXXX 500
S+G GQQ+ SLS + IDPSS++RAYAALGL
Sbjct: 456 IGSVGAGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQ--QPAQPPA 513
Query: 501 XXXMRSVNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINSQNPMM---SGNAGVASL 554
MR++N + +PM V G Q PNL+S+S L +++ + NP+M S + + SL
Sbjct: 514 HQQMRTLNALGNNPMSVPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGSL 573
Query: 555 GPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYAR 614
+PTAA PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+
Sbjct: 574 STIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAK 633
Query: 615 KVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGM 665
KVEGDMYESAN+R EYYHLLAEKIYKIQKELEEKRRTRL KQ +L N P +
Sbjct: 634 KVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPAL 684
>gi|737920|prf||1923401A protein CBP
Length = 2441
Score = 473 bits (1216), Expect = e-132
Identities = 336/711 (47%), Positives = 405/711 (56%), Gaps = 73/711 (10%)
Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
MAEN+++ GPP D TDFGSLFDLE+DLPDELI + EL L N G+
Sbjct: 1 MAENLLD-GPP--NPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIPNGELSLLNSGN 57
Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQA--------MASQACQNS 112
+V DAASKHKQLSELLR GS ++N G+G + +Q NS
Sbjct: 58 ---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNS 108
Query: 113 PGLSLINSMVKSPMACTGLTSPNM---GIGSSGPNQGPTQS------------------- 150
++ + +M KSP+ ++PN+ +SGP +Q+
Sbjct: 109 TNMASLGAMGKSPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATS 168
Query: 151 ---PAGMMNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSI--GAGRGRPN 205
P MN+ NQ G QVMNGS+
Sbjct: 169 QTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQA------QVMNGSLGAAGRGRGAG 222
Query: 206 MQYPNAGM-GNAGSLLTE---XXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQN 261
M YP M G S+L E KMGM SP+G P++Q
Sbjct: 223 MPYPAPAMQGATSSVLAETLTQVSPQMAGHAGLNTAQAGGMTKMGMTGTTSPFGQPFSQT 282
Query: 262 SGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPVA 321
GQQ+GA+G+ Q+ +K + N+L F D K G+V A
Sbjct: 283 GGQQMGATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMSQLQ----TSVGIVPTQA 338
Query: 322 AGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMT 381
G TADPEKR +IQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMT
Sbjct: 339 IATGP---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMT 395
Query: 382 HCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGNP 441
HCQ+ K+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQ +IL G+ N
Sbjct: 396 HCQAPKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNT 455
Query: 442 -SSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNXXXXXXXXX 500
S+G GQQ+ SLS + IDPSS++RAYAALGL
Sbjct: 456 IGSVGAGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQ--QPAQPPA 513
Query: 501 XXXMRSVNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINSQNPMM---SGNAGVASL 554
MR++N + +PM V G Q PNL+S+S L +++ + NP+M S + + SL
Sbjct: 514 HQQMRTLNALGNNPMSVPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGSL 573
Query: 555 GPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYAR 614
+PTAA PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+
Sbjct: 574 STIPTAAPPSSTGVRKGWHERVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAK 633
Query: 615 KVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGM 665
KVEGDMYESAN+R EYYHLLAEKIYKIQKELEEKRRTRL KQ +L N P +
Sbjct: 634 KVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPAL 684
>gi|19547885|gb|AAL87531.1| CREB-binding protein [Mus musculus]
gi|19547887|gb|AAL87532.1| CREB-binding protein [Mus musculus]
Length = 2429
Score = 471 bits (1213), Expect = e-131
Identities = 328/683 (48%), Positives = 396/683 (57%), Gaps = 70/683 (10%)
Query: 29 DGTDFGSLFDLEHDLPDELINSTELGLTNGGDSSQLQTSLGIVQDAASKHKQLSELLRSG 88
D TDFGSLFDLE+DLPDELI + EL L N G+ +V DAASKHKQLSELLR G
Sbjct: 20 DNTDFGSLFDLENDLPDELIPNGELSLLNSGN---------LVPDAASKHKQLSELLRGG 70
Query: 89 SSPNLNMGVGGPGQA--------MASQACQNSPGLSLINSMVKSPMACTGLTSPNM---G 137
S ++N G+G + +Q NS ++ + +M KSP+ ++PN+
Sbjct: 71 SGSSINPGIGNVSASSPVQQGLGGQAQGQPNSTNMASLGAMGKSPLNQGDSSTPNLPKQA 130
Query: 138 IGSSGPNQGPTQS----------------------PAGMMNSPVNQXXXXXXXXXXXXXX 175
+SGP +Q+ P MN+ NQ
Sbjct: 131 ASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSL 190
Query: 176 XXXLAAGNGQGIMPNQVMNGSI--GAGRGRPNMQYPNAGM-GNAGSLLTE---XXXXXXX 229
G QVMNGS+ M YP M G S+L E
Sbjct: 191 MNQAQQGQA------QVMNGSLGAAGRGRGAGMPYPAPAMQGATSSVLAETLTQVSPQMA 244
Query: 230 XXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFA 289
KMGM SP+G P++Q GQQ+GA+G+ Q+ +K + N+L F
Sbjct: 245 GHAGLNTAQAGGMTKMGMTGTTSPFGQPFSQTGGQQMGATGVNPQLASKQSMVNSLPAFP 304
Query: 290 MDKKAVXXXXXXXXXXXXXXSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHA 349
D K G+V A G TADPEKR +IQQQLVLLLHA
Sbjct: 305 TDIKNTSVTTVPNMSQLQ----TSVGIVPTQAIATGP---TADPEKRKLIQQQLVLLLHA 357
Query: 350 HKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTR 409
HKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+GK+CQVAHCASSRQIISHWKNCTR
Sbjct: 358 HKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTR 417
Query: 410 HDCPVCLPLKNAGDKRNQCSILTGAPVGLGNP-SSLGVGQQSTPSLSTVSQIDPSSIERA 468
HDCPVCLPLKNA DKRNQ +IL G+ N S+G GQQ+ SLS + IDPSS++RA
Sbjct: 418 HDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSMQRA 477
Query: 469 YAALGLXXXXXXXXXXXXXXAKNXXXXXXXXXXXXMRSVNNMSASPMGVNGG---VGVQT 525
YAALGL MR++N + +PM + G Q
Sbjct: 478 YAALGLPYMNQPQTQLQPQVPGQ--QPAQPPAHQQMRTLNALGNNPMSIPAGGITTDQQP 535
Query: 526 PNLLSDSMLHSTINSQNPMM---SGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRN 582
PNL+S+S L +++ + NP+M S + + SL +PTAA PSSTG+RK WHE +TQDLR+
Sbjct: 536 PNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLRS 595
Query: 583 HLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQ 642
HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGDMYESAN+R EYYHLLAEKIYKIQ
Sbjct: 596 HLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQ 655
Query: 643 KELEEKRRTRLQKQNMLPNAPGM 665
KELEEKRR+RL KQ +L N P +
Sbjct: 656 KELEEKRRSRLHKQGILGNQPAL 678
>gi|631119|pir||S39162 transcription coactivator CREB-binding protein - human
Length = 2440
Score = 468 bits (1205), Expect = e-130
Identities = 339/735 (46%), Positives = 417/735 (56%), Gaps = 75/735 (10%)
Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG 59
MAEN+++ GPP TDFGSLFDLE+DLPDELI N ELGL N G
Sbjct: 1 MAENLLD-GPP--NPKRAKLSSPGFSANSNTDFGSLFDLENDLPDELIPNGGELGLLNSG 57
Query: 60 DSSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQA--------MASQACQN 111
+ +V DAASKHKQLSELLR GS ++N G+G + +Q N
Sbjct: 58 N---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN 108
Query: 112 SPGLSLINSMVKSPMACTGLTSPNM---GIGSSGPNQGPTQS------------------ 150
S ++ +++M KSP++ +SP++ +SGP +Q+
Sbjct: 109 SANMASLSAMGKSPLSQGDSSSPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT 168
Query: 151 ----PAGMMNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSIGAGRGRPNM 206
P MN+ NQ + G QVMNGS+GA
Sbjct: 169 SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQA------QVMNGSLGAAGRGRGA 222
Query: 207 QYP---NAGMGNAGSLLTE---XXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQ 260
P A G + S+L E K+GM SP+G P++Q
Sbjct: 223 GMPYTAPAMQGASSSVLAETLTQVSPQTAGHAGLNTAQAGGMAKIGMNGTTSPFGQPFSQ 282
Query: 261 NSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPV 320
GQ +GA+G+ Q+ +K + N+L F D K G+V
Sbjct: 283 AGGQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQ----TSVGIVPTQ 338
Query: 321 AAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHM 380
A G TADPEKR +IQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHM
Sbjct: 339 AIATGP---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHM 395
Query: 381 THCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGN 440
THCQ+GK+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQ +IL G+ N
Sbjct: 396 THCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQN 455
Query: 441 P-SSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNXXXXXXXX 499
S+G GQQ+ SLS + IDPSS++RAYAALGL
Sbjct: 456 TIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQ--QPAQPQ 513
Query: 500 XXXXMRSVNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINSQNPMM---SGNAGVAS 553
MR++N + +PM + G Q PNL+S+S L +++ + NP+M S + + +
Sbjct: 514 THQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGT 573
Query: 554 LGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYA 613
L +PTAA PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA
Sbjct: 574 LSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYA 633
Query: 614 RKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGMGPVPMNTG 673
+KVEGDMYESAN+R EYYHLLAEKIYKIQKELEEKRR+RL KQ +L N P + P P
Sbjct: 634 KKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPAL-PAPGAQP 692
Query: 674 SNMGQQPTGMTTNGP 688
+ Q + NGP
Sbjct: 693 PVIPQAQSVRPPNGP 707
>gi|27881767|gb|AAH44677.1| Similar to CREB binding protein (Rubinstein-Taybi syndrome)
[Xenopus laevis]
Length = 1047
Score = 427 bits (1099), Expect = e-118
Identities = 349/731 (47%), Positives = 424/731 (58%), Gaps = 71/731 (9%)
Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
MAEN+++ GPP D TDF S FDLE+DLPDELI NGG+
Sbjct: 1 MAENLLD-GPP-NRKRPKLSSPGFSASTDSTDF-SFFDLENDLPDELI-------PNGGE 50
Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSP-NLNMGVGGPGQAM----ASQACQNSPGL 115
S L T + QDAAS+++QLS+LLR G++ MG G G + SQ Q+SPGL
Sbjct: 51 LSILGTGGSLGQDAASQNRQLSDLLRGGNAGLGAAMGRGRSGSPVQQGLGSQGQQHSPGL 110
Query: 116 SLINSMVKSPM-------ACTGLTSPNMGIGSSGP-------------NQGPTQSPAGM- 154
+ S+ KSP+ + GLT G S P + P+Q P G+
Sbjct: 111 GNLGSLNKSPLNQGLSVTSPAGLTKTTGTPGPSVPASQAQKQVSMVAGSTAPSQVPTGLC 170
Query: 155 MNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSIGAG-RGRPN-MQYPNAG 212
MNS NQ G QV+NGS+G G RGR +QY +
Sbjct: 171 MNSNFNQGHQTLLNSNSGHTLMSQAQPAQG------QVLNGSLGVGSRGRGTALQYNSPA 224
Query: 213 M-GNAGSLLTE---XXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQNSGQQIGA 268
M N GS+L E KMG+ N SP+G + Q +GQQI A
Sbjct: 225 MQTNPGSVLAETLTQGTATMPTHAGMTTAQTGAMNKMGLPGNTSPFGQTFNQAAGQQIRA 284
Query: 269 SGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPVAAGMGSGA 328
G+ Q+ K + N+L PF D K VQQ G+ T + G G
Sbjct: 285 QGVSPQLPAKPAMANSLPPFPSDIKNA-PVANLPNMSPLQAQVQQVGIGTSPSMGTGP-- 341
Query: 329 HTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKS 388
TADPEKR +IQQQLVLLLHAHKCQRREQANGE+R C+LPHCRTMKNVLNHMTHCQ+GK+
Sbjct: 342 -TADPEKRKLIQQQLVLLLHAHKCQRREQANGEMRDCSLPHCRTMKNVLNHMTHCQAGKA 400
Query: 389 CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGNPSSLGVGQ 448
CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQ ++ A + G GQ
Sbjct: 401 CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQNLPVSLASGVQSPIGTTGGGQ 460
Query: 449 QSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNXXXXXXXXXXXXMRSVN 508
Q+ PSLS+ + IDPSS++RAYAALGL +R++N
Sbjct: 461 QTAPSLSSPNPIDPSSMQRAYAALGLPYGNPAQGTGQQPAQTQ--------VHQQIRNMN 512
Query: 509 NMSASPMGVN-GGVGV-QTPNLLSDSMLHSTINSQNPMMS---GNAGVASLGPLPTAAQP 563
+ + M + GG+ V Q NL+SD+ L + + + N ++S G + V + G +PTAA P
Sbjct: 513 ALGGNQMNLTAGGMTVEQQTNLISDTALPTALANSNSLLSDGNGQSTVGNHGTMPTAAPP 572
Query: 564 SSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYES 623
SSTG+RK WHE +TQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYES
Sbjct: 573 SSTGVRKAWHEHVTQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYES 632
Query: 624 ANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPN-----APGMGPVPM-NTGSNMG 677
AN+R EYYH LAEKIYKIQKELEEKRR+RLQKQ ++ + APG P + T +G
Sbjct: 633 ANSRDEYYHFLAEKIYKIQKELEEKRRSRLQKQGIMSSQAPLQAPGAQPTALTQTSPALG 692
Query: 678 QQPTGMTTNGP 688
Q TNGP
Sbjct: 693 QTQPVRPTNGP 703
>gi|19173764|ref|NP_596894.1| E1A binding protein p300 [Rattus norvegicus]
gi|15076626|dbj|BAB62425.1| E1A-binding protein [Rattus norvegicus]
Length = 353
Score = 414 bits (1065), Expect = e-114
Identities = 272/353 (77%), Positives = 276/353 (78%)
Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
MAENVVEPGPP DGTDFGSLFDLEHDLPDELINSTELGLTNGGD
Sbjct: 1 MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQACQNSPGLSLINS 120
SQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQ MASQA QNSPGLSLINS
Sbjct: 61 ISQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQNSPGLSLINS 120
Query: 121 MVKSPMACTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQXXXXXXXXXXXXXXXXXLA 180
MVKSPMA TGLTSPNMG+GSSGPNQGPTQS AGMMNSPVNQ LA
Sbjct: 121 MVKSPMAQTGLTSPNMGMGSSGPNQGPTQSTAGMMNSPVNQPAMGMNTGMNAGMNPGMLA 180
Query: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEXXXXXXXXXXXXXXXXXX 240
AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTE
Sbjct: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEPLQQGSPQMGGQPGLRGP 240
Query: 241 XXLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXX 300
KMGMM+NP+PYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAV
Sbjct: 241 QSHKMGMMSNPTPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVTGGGM 300
Query: 301 XXXXXXXXXSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQ 353
SVQQPGLV PVA GMGSGAHTADPEKR +IQQQLVLLLHAHKCQ
Sbjct: 301 PNMGQQPTPSVQQPGLVNPVAPGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQ 353
>gi|2996629|gb|AAC08447.1| CBP [Homo sapiens]
Length = 555
Score = 390 bits (1001), Expect = e-107
Identities = 255/451 (56%), Positives = 303/451 (67%), Gaps = 17/451 (3%)
Query: 245 MGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXX 304
MG+ N SP+G P++Q GQ +GA+G+ Q+ +K + N+L F D K
Sbjct: 1 MGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMS 60
Query: 305 XXXXXSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQ 364
G+V A G TADPEKR +IQQQLVLLLHAHKCQRREQANGEVR
Sbjct: 61 QMQ----TSVGIVPTQAIATGP---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRA 113
Query: 365 CNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDK 424
C+LPHCRTMKNVLNHMTHCQ+GK+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DK
Sbjct: 114 CSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDK 173
Query: 425 RNQCSILTGAPVGLGNP-SSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXX 483
RNQ +IL G+ N S+G GQQ+ SLS + IDPSS++RAYAALGL
Sbjct: 174 RNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQ 233
Query: 484 XXXXXAKNXXXXXXXXXXXXMRSVNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINS 540
MR++N + +PM + G Q PNL+S+S L +++ +
Sbjct: 234 LQPQVPGQ--QPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGA 291
Query: 541 QNPMM---SGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPD 597
NP+M S + + +L +PTAA PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPD
Sbjct: 292 TNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPD 351
Query: 598 PAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQN 657
PAALKDRRMENLVAYA+KVEGDMYESAN+R EYYHLLAEKIYKIQKELEEKRR+RL KQ
Sbjct: 352 PAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQG 411
Query: 658 MLPNAPGMGPVPMNTGSNMGQQPTGMTTNGP 688
+L N P + P P + Q NGP
Sbjct: 412 ILGNQPAL-PAPGAQPPVIPQAQPVRPPNGP 441
>gi|21307831|gb|AAL54859.1| CREB-binding protein [Aplysia californica]
Length = 2245
Score = 249 bits (637), Expect = 9e-65
Identities = 244/653 (37%), Positives = 306/653 (46%), Gaps = 103/653 (15%)
Query: 32 DFGSL-FD-LEHDLPDELINSTELGLTNGGDSSQLQTSLGIVQDAASKHKQLSELLRSGS 89
+FG+L FD + ++LPD+L GL G S QT G QD S LS+LL S S
Sbjct: 31 NFGNLNFDGIVNELPDDLD-----GLQ--GTSGDGQTPQG-SQD-TSMGGSLSQLL-SRS 80
Query: 90 SPNLNMGVGGPGQAMASQACQNSP--GLSLINSMVKSPMACTGLTSPNMGIGSSGPNQGP 147
+PN + P + SP G + M K+PM+ + ++ N+
Sbjct: 81 TPNSQTSLPLPVNSAGGIQTSRSPGMGAMMNMGMGKNPMS--------NNLAATLANKAA 132
Query: 148 TQSPAGMMNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSIGAGRGRPNMQ 207
T S M ++ V+ G M N M GS+G+ N Q
Sbjct: 133 TSSHMNMNDALVSSASFTISGTNAGPMGGVTNTMGMNP-TMGNPQMIGSVGS--LNMNQQ 189
Query: 208 YPNAGMGNAGSLLTEXXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQNSGQQIG 267
PN M S + GMM +P G P Q G
Sbjct: 190 MPNQMMNGPTSFPGNMGQMRAMQGNNVNPSTSMQVPQTGMMQSP---GMPQMQGHQGMPG 246
Query: 268 ASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPVAAGMGSG 327
+ + P N+ P P +G
Sbjct: 247 HPNMNMPQNP----PQNIRPG-----------------------------QPTGSGTSGP 273
Query: 328 AHTA-DPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSG 386
A +P+K +IQQQLVLLLHAHKCQRREQ N E ++C LP+CRTMKNVLNHMT C G
Sbjct: 274 RQAAGEPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKG 332
Query: 387 KSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGNPSSLGV 446
KSC+VAHCASSRQII+HWKNC R DCPVC LK A DKRN + G
Sbjct: 333 KSCEVAHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRN----------------TQGQ 375
Query: 447 GQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNXXXXXXXXXXXXMRS 506
T +++ + DP++++RA+ +LGL A N
Sbjct: 376 SVNQTSTMTAPNAADPATMKRAFESLGL-------QYNQNTPAHNAAQHGHPQMNAMQND 428
Query: 507 VNNMSASPMGVNGGVGVQTPNLLSDSM----------LHSTINSQN--PMMSGNAGVASL 554
++ + M G V P+ S M L TI Q+ + S A A++
Sbjct: 429 AGQINKTNMPNQQGPKV-VPDQSSSPMSMLPVPPTGQLPQTIQPQSGTQLASATAQAAAM 487
Query: 555 GPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYAR 614
G P + RK WH +TQDLRNHLVHKLVQAIFPTPD A L+D RM+NLVAYAR
Sbjct: 488 GNAPDIVKSIPVSSRKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYAR 547
Query: 615 KVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNA--PGM 665
KVEGDMYESANNR +YYHLLAEKIYKIQKELEEKR R++ QN PNA PGM
Sbjct: 548 KVEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQNA-PNAQVPGM 599
>gi|20664269|pdb|1L3E|B Chain B, Nmr Structures Of The Hif-1alpha CtadP300 CH1 COMPLEX
gi|33357860|pdb|1P4Q|B Chain B, Solution Structure Of The Cited2 Transactivation Domain In
Complex With The P300 Ch1 Domain
Length = 101
Score = 194 bits (494), Expect = 3e-48
Identities = 99/101 (98%), Positives = 100/101 (99%)
Query: 324 MGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHC 383
MGSGAHTADPEKR +IQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHC
Sbjct: 1 MGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHC 60
Query: 384 QSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDK 424
QSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDK
Sbjct: 61 QSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDK 101
>gi|20664319|pdb|1L8C|A Chain A, Structural Basis For Hif-1alphaCBP RECOGNITION IN THE
Cellular Hypoxic Response
Length = 95
Score = 179 bits (453), Expect = 2e-43
Identities = 88/95 (92%), Positives = 92/95 (96%)
Query: 331 ADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQ 390
ADPEKR +IQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+GK+CQ
Sbjct: 1 ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQ 60
Query: 391 VAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKR 425
VAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKR
Sbjct: 61 VAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKR 95
>gi|4139873|pdb|1KDX|A Chain A, Kix Domain Of Mouse Cbp (Creb Binding Protein) In Complex
With Phosphorylated Kinase Inducible Domain (Pkid) Of
Rat Creb (Cyclic Amp Response Element Binding Protein),
Nmr 17 Structures
Length = 81
Score = 164 bits (415), Expect = 5e-39
Identities = 72/80 (90%), Positives = 77/80 (96%)
Query: 568 IRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNR 627
+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGDMYESAN+R
Sbjct: 2 VRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSR 61
Query: 628 AEYYHLLAEKIYKIQKELEE 647
EYYHLLAEKIYKIQKELEE
Sbjct: 62 DEYYHLLAEKIYKIQKELEE 81
>gi|17553334|ref|NP_499197.1| CREB-binding protein like family member (22.2 kD) (3L5)
[Caenorhabditis elegans]
gi|542476|pir||S42836 F40F12.7 protein - Caenorhabditis elegans
gi|3877001|emb|CAA82938.1| Hypothetical protein F40F12.7 [Caenorhabditis elegans]
Length = 199
Score = 130 bits (328), Expect = 7e-29
Identities = 63/108 (58%), Positives = 72/108 (66%), Gaps = 9/108 (8%)
Query: 332 DPEKRNVIQQQLVLLLHAHKCQRREQANGEV---------RQCNLPHCRTMKNVLNHMTH 382
DP KR +IQQQ VLLLHAHKC +RE+ N E C LPHC TMK VL HMT+
Sbjct: 7 DPVKRKLIQQQFVLLLHAHKCSQREKENNEFAARNQLLPHAACTLPHCSTMKEVLIHMTN 66
Query: 383 CQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSI 430
C G+ C AHCASSRQII+HWK+C+R DCPVC PLK D Q S+
Sbjct: 67 CNVGRLCHFAHCASSRQIIAHWKDCSREDCPVCKPLKGIQDTPLQFSL 114
>gi|17552708|ref|NP_499161.1| CBP/p300 homolog (cbp-1) [Caenorhabditis elegans]
gi|14530537|emb|CAA82353.2| C. elegans CBP-1 protein (corresponding sequence R10E11.1a)
[Caenorhabditis elegans]
Length = 2045
Score = 124 bits (310), Expect = 7e-27
Identities = 60/101 (59%), Positives = 78/101 (77%)
Query: 555 GPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYAR 614
G +P P K+WH +T+DLRNHLV KLV+AIFP P+ A+ D R+++L+AYAR
Sbjct: 570 GEIPNLPPPDMPDCTKEWHHQVTKDLRNHLVGKLVKAIFPEPNQEAMNDNRLKDLIAYAR 629
Query: 615 KVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQK 655
KVE +M+ESAN+R EYYHLLAEKIYKIQKEL+EK+ +RL +
Sbjct: 630 KVEKEMFESANDREEYYHLLAEKIYKIQKELQEKKNSRLNQ 670
Score = 109 bits (273), Expect = 2e-22
Identities = 69/130 (53%), Positives = 79/130 (60%), Gaps = 9/130 (6%)
Query: 310 SVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEV------- 362
+ Q+ G G A DPEKR +IQQQLVLLLHAHKC +RE+ N +
Sbjct: 377 AAQRNGAGRATTPGSSMLATHQDPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPP 436
Query: 363 --RQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420
C LPHC TMK VL HMT C G+ C AHCASSRQII+HWKNC+R DCPVC PLK
Sbjct: 437 PHAACTLPHCSTMKEVLTHMTSCNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCKPLKR 496
Query: 421 AGDKRNQCSI 430
D Q S+
Sbjct: 497 IQDTPLQFSL 506
>gi|31204369|ref|XP_311133.1| ENSANGP00000004748 [Anopheles gambiae]
gi|30178093|gb|EAA06516.2| ENSANGP00000004748 [Anopheles gambiae str. PEST]
Length = 2572
Score = 121 bits (304), Expect = 4e-26
Identities = 77/149 (51%), Positives = 92/149 (61%), Gaps = 12/149 (8%)
Query: 504 MRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMMSGNAGVASLGPLPTAAQP 563
M +N + S M G G PN + S + S+ +P
Sbjct: 689 MPLMNATNTSTM---SGGGGGGPN--TSSFAAGSGAGGGGAGGTGGTNPSMVAVPVQGT- 742
Query: 564 SSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYES 623
K WH +T DLRNHLVHKLVQAIFP+PDP+A+ D+RM NLVAYA+KVEGDMYE
Sbjct: 743 ------KDWHHSVTPDLRNHLVHKLVQAIFPSPDPSAMFDKRMYNLVAYAKKVEGDMYEM 796
Query: 624 ANNRAEYYHLLAEKIYKIQKELEEKRRTR 652
AN+R+EYYHLLAEKIYKIQKELEEKR+ R
Sbjct: 797 ANSRSEYYHLLAEKIYKIQKELEEKRQKR 825
Score = 115 bits (288), Expect = 2e-24
Identities = 66/101 (65%), Positives = 73/101 (72%)
Query: 325 GSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQ 384
G ADPEKR +IQQQLVLLLHAHKCQRRE N C+L HCRTMK VL HM C
Sbjct: 332 GGNPLLADPEKRKLIQQQLVLLLHAHKCQRREAENPSGNICSLAHCRTMKEVLTHMQSCL 391
Query: 385 SGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKR 425
GK+C HC+SSRQII+HWKNC R DCPVCLPL+ DK+
Sbjct: 392 LGKNCPKTHCSSSRQIINHWKNCQRQDCPVCLPLQQHHDKQ 432
>gi|7511830|pir||T13828 CREB-binding protein homolog - fruit fly (Drosophila melanogaster)
gi|1916930|gb|AAB53050.1| CREB-binding protein homolog [Drosophila melanogaster]
Length = 3190
Score = 118 bits (295), Expect = 4e-25
Identities = 70/137 (51%), Positives = 84/137 (61%)
Query: 516 GVNGGVGVQTPNLLSDSMLHSTINSQNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHED 575
G +GG ++L + + N+ NP + G K W E
Sbjct: 887 GASGGQVAAGSSVLMPADTTGSGNAGNPNQNAGGVAGGAGGGNGGNTGPPGDNEKDWRES 946
Query: 576 ITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLA 635
+T DLRNHLVHKLVQAIFPT DP ++D+RM NLV+YA KVE DMYE A +R+EYYHLLA
Sbjct: 947 VTADLRNHLVHKLVQAIFPTSDPTTMQDKRMHNLVSYAEKVEKDMYEMAKSRSEYYHLLA 1006
Query: 636 EKIYKIQKELEEKRRTR 652
EKIYKIQKELEEKR R
Sbjct: 1007 EKIYKIQKELEEKRLKR 1023
Score = 80.9 bits (198), Expect = 7e-14
Identities = 45/99 (45%), Positives = 61/99 (61%)
Query: 321 AAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHM 380
++G G +++ IQQQL+LLLHAHKC RRE N CN+ +C+ MK+VL HM
Sbjct: 497 SSGPGGANRDVPDDRKRQIQQQLMLLLHAHKCNRRENLNPNREVCNVNYCKAMKSVLAHM 556
Query: 381 THCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 419
C+ K C + HCASSRQI+ H+K C C +C P +
Sbjct: 557 GTCKQSKDCTMQHCASSRQILLHYKTCQNSGCVICYPFR 595
Score = 38.9 bits (89), Expect = 0.35
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 13/88 (14%)
Query: 331 ADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQ 390
A+P++ Q + AH CQ R+ C LP C+ MK V+ H +C+ +
Sbjct: 2389 ANPQEARKQSIQRCIQSLAHACQCRDA------NCRLPSCQKMKLVVQHTKNCKRKPN-- 2440
Query: 391 VAHCASSRQIIS----HWKNCTRHDCPV 414
C +Q+I+ H KNC CPV
Sbjct: 2441 -GGCPICKQLIALCCYHAKNCEEQKCPV 2467
>gi|24640865|ref|NP_524642.2| nejire CG15319-PB [Drosophila melanogaster]
gi|22833041|gb|AAF46516.2| CG15319-PB [Drosophila melanogaster]
Length = 3276
Score = 117 bits (293), Expect = 7e-25
Identities = 70/137 (51%), Positives = 84/137 (61%)
Query: 516 GVNGGVGVQTPNLLSDSMLHSTINSQNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHED 575
G +GG ++L + + N+ NP + G K W E
Sbjct: 887 GASGGQVAAGSSVLMPADTTGSGNAGNPNQNAGGVAGGAGGGNGGNTGPPGDNEKDWRES 946
Query: 576 ITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLA 635
+T DLRNHLVHKLVQAIFPT DP ++D+RM NLV+YA KVE DMYE A +R+EYYHLLA
Sbjct: 947 VTADLRNHLVHKLVQAIFPTSDPTTMQDKRMHNLVSYAEKVEKDMYEMAKSRSEYYHLLA 1006
Query: 636 EKIYKIQKELEEKRRTR 652
EKIYKIQKELEEKR R
Sbjct: 1007 EKIYKIQKELEEKRLKR 1023
Score = 80.5 bits (197), Expect = 1e-13
Identities = 45/99 (45%), Positives = 61/99 (61%)
Query: 321 AAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHM 380
++G G +++ IQQQL+LLLHAHKC RRE N CN+ +C+ MK+VL HM
Sbjct: 497 SSGPGGANRDVPDDRKRQIQQQLMLLLHAHKCNRRENLNPNREVCNVNYCKAMKSVLAHM 556
Query: 381 THCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 419
C+ K C + HCASSRQI+ H+K C C +C P +
Sbjct: 557 GTCKQSKDCTMQHCASSRQILLHYKTCQNSGCVICYPFR 595
Score = 38.5 bits (88), Expect = 0.44
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 13/88 (14%)
Query: 331 ADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQ 390
A+P++ Q + AH CQ R+ C LP C+ MK V+ H +C+ +
Sbjct: 2389 ANPQEARKQSIQRCIQSLAHACQCRDA------NCRLPSCQKMKLVVQHTKNCKRKPN-- 2440
Query: 391 VAHCASSRQIIS----HWKNCTRHDCPV 414
C +Q+I+ H KNC CPV
Sbjct: 2441 -GGCPICKQLIALCCYHAKNCEEQKCPV 2467
>gi|7494646|pir||T37269 hypothetical protein - Caenorhabditis elegans (fragment)
gi|2665395|dbj|BAA23766.1| unnamed protein product [Caenorhabditis elegans]
Length = 118
Score = 117 bits (293), Expect = 8e-25
Identities = 65/108 (60%), Positives = 73/108 (67%), Gaps = 9/108 (8%)
Query: 332 DPEKRNVIQQQLVLLLHAHKCQRREQANGEV---------RQCNLPHCRTMKNVLNHMTH 382
DPEKR +IQQQLVLLLHAHKC +RE+ N + C LPHC TMK VL HMT
Sbjct: 3 DPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTS 62
Query: 383 CQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSI 430
C G+ C AHCASSRQII+HWKNC+R DCPVC PLK D Q S+
Sbjct: 63 CNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCKPLKRIQDTPLQFSL 110
>gi|482238|pir||S41033 hypothetical protein K03H1.10 - Caenorhabditis elegans (fragment)
Length = 316
Score = 110 bits (276), Expect = 6e-23
Identities = 61/101 (60%), Positives = 70/101 (69%), Gaps = 9/101 (8%)
Query: 332 DPEKRNVIQQQLVLLLHAHKCQRREQANGEV---------RQCNLPHCRTMKNVLNHMTH 382
DP K+ ++QQQLVLLLHAHKC R++ N E C LPHC TMK VL HMT+
Sbjct: 1 DPVKQKLVQQQLVLLLHAHKCSLRDKENNEFAARNQPLPHTTCRLPHCPTMKEVLIHMTN 60
Query: 383 CQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGD 423
C G+ C AHCASSRQII+HWKNC+R DCPVC PLK A D
Sbjct: 61 CNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCTPLKRARD 101
Score = 105 bits (263), Expect = 2e-21
Identities = 55/112 (49%), Positives = 77/112 (68%), Gaps = 5/112 (4%)
Query: 544 MMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKD 603
M +G ++ LP P T K+WH +T DLRNH+V KLV+AI P P+ + D
Sbjct: 138 MSAGRITNGNISNLPPPNVPVRT---KEWHRQVTNDLRNHIVGKLVKAICPAPE--MMND 192
Query: 604 RRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQK 655
R+++L AYARKVE +++E+A +R YYHLLAEKIY+IQKEL+EK+ +RL +
Sbjct: 193 IRLKDLNAYARKVEKEVFETAIDRKNYYHLLAEKIYEIQKELQEKKNSRLNQ 244
>gi|17554044|ref|NP_499201.1| CREB-binding protein like family member (36.7 kD) (3L15)
[Caenorhabditis elegans]
gi|25395947|pir||D88569 protein K03H1.10 [imported] - Caenorhabditis elegans
gi|3877003|emb|CAA82940.1| Hypothetical protein K03H1.10 [Caenorhabditis elegans]
gi|3878179|emb|CAA82665.1| Hypothetical protein K03H1.10 [Caenorhabditis elegans]
Length = 322
Score = 110 bits (276), Expect = 7e-23
Identities = 61/101 (60%), Positives = 70/101 (69%), Gaps = 9/101 (8%)
Query: 332 DPEKRNVIQQQLVLLLHAHKCQRREQANGEV---------RQCNLPHCRTMKNVLNHMTH 382
DP K+ ++QQQLVLLLHAHKC R++ N E C LPHC TMK VL HMT+
Sbjct: 7 DPVKQKLVQQQLVLLLHAHKCSLRDKENNEFAARNQPLPHTTCRLPHCPTMKEVLIHMTN 66
Query: 383 CQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGD 423
C G+ C AHCASSRQII+HWKNC+R DCPVC PLK A D
Sbjct: 67 CNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCTPLKRARD 107
Score = 105 bits (262), Expect = 3e-21
Identities = 55/112 (49%), Positives = 77/112 (68%), Gaps = 5/112 (4%)
Query: 544 MMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKD 603
M +G ++ LP P T K+WH +T DLRNH+V KLV+AI P P+ + D
Sbjct: 144 MSAGRITNGNISNLPPPNVPVRT---KEWHRQVTNDLRNHIVGKLVKAICPAPE--MMND 198
Query: 604 RRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQK 655
R+++L AYARKVE +++E+A +R YYHLLAEKIY+IQKEL+EK+ +RL +
Sbjct: 199 IRLKDLNAYARKVEKEVFETAIDRKNYYHLLAEKIYEIQKELQEKKNSRLNQ 250
>gi|2133462|pir||S60123 hypothetical protein R10E11.1 - Caenorhabditis elegans
Length = 2027
Score = 105 bits (261), Expect = 3e-21
Identities = 71/141 (50%), Positives = 81/141 (57%), Gaps = 20/141 (14%)
Query: 310 SVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEV------- 362
+ Q+ G G A DPEKR +IQQQLVLLLHAHKC +RE+ N +
Sbjct: 377 AAQRNGAGRATTPGSSMLATHQDPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPP 436
Query: 363 --RQCNLPHCRTMKNVLNHMTHC-----------QSGKSCQVAHCASSRQIISHWKNCTR 409
C LPHC TMK VL HMT C Q+ K C VAHCASSRQII+HWKNC+R
Sbjct: 437 PHAACTLPHCSTMKEVLTHMTSCNVGRLCHSDTTQTTKKCSVAHCASSRQIIAHWKNCSR 496
Query: 410 HDCPVCLPLKNAGDKRNQCSI 430
DCPVC PLK D Q S+
Sbjct: 497 EDCPVCKPLKRIQDTPLQFSL 517
>gi|17552710|ref|NP_499160.1| CBP/p300 homolog (cbp-1) [Caenorhabditis elegans]
gi|20455476|sp|P34545|CBP1_CAEEL Protein cbp-1
gi|25299632|pir||G88564 protein R10E11.1 [imported] - Caenorhabditis elegans
gi|17645979|emb|CAD18875.1| C. elegans CBP-1 protein (corresponding sequence R10E11.1b)
[Caenorhabditis elegans]
Length = 2056
Score = 104 bits (260), Expect = 4e-21
Identities = 71/141 (50%), Positives = 81/141 (57%), Gaps = 20/141 (14%)
Query: 310 SVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEV------- 362
+ Q+ G G A DPEKR +IQQQLVLLLHAHKC +RE+ N +
Sbjct: 377 AAQRNGAGRATTPGSSMLATHQDPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPP 436
Query: 363 --RQCNLPHCRTMKNVLNHMTHC-----------QSGKSCQVAHCASSRQIISHWKNCTR 409
C LPHC TMK VL HMT C Q+ K C VAHCASSRQII+HWKNC+R
Sbjct: 437 PHAACTLPHCSTMKEVLTHMTSCNVGRLCHSDTTQTTKKCSVAHCASSRQIIAHWKNCSR 496
Query: 410 HDCPVCLPLKNAGDKRNQCSI 430
DCPVC PLK D Q S+
Sbjct: 497 EDCPVCKPLKRIQDTPLQFSL 517
>gi|17552400|ref|NP_497145.1| CREB-binding protein like family member (3A735) [Caenorhabditis
elegans]
gi|7496696|pir||T33580 hypothetical protein C29F9.5 - Caenorhabditis elegans
gi|3790687|gb|AAC68747.1| Hypothetical protein C29F9.5 [Caenorhabditis elegans]
Length = 226
Score = 92.4 bits (228), Expect = 2e-17
Identities = 42/90 (46%), Positives = 52/90 (57%), Gaps = 9/90 (10%)
Query: 338 VIQQQLVLLLHAHKCQRREQANGEVRQ---------CNLPHCRTMKNVLNHMTHCQSGKS 388
+I +QL LLLHAH+C RR+ E + C + C MK VL HMT C+ G
Sbjct: 4 LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
Query: 389 CQVAHCASSRQIISHWKNCTRHDCPVCLPL 418
C HCASSR I+SHWK C +CPVC P+
Sbjct: 64 CNSVHCASSRTILSHWKKCFNEECPVCKPI 93
Score = 54.3 bits (129), Expect = 7e-06
Identities = 23/93 (24%), Positives = 47/93 (50%)
Query: 559 TAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG 618
T A+P + WH ++ + R+ L+ K+ + I P L + +M+ Y+R E
Sbjct: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164
Query: 619 DMYESANNRAEYYHLLAEKIYKIQKELEEKRRT 651
++++A YYH+ EK+ + Q+ +++T
Sbjct: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
>gi|19173734|ref|NP_596872.1| CREB binding protein; Creb binding protein (CBP) [Rattus
norvegicus]
gi|15076624|dbj|BAB62424.1| CREB-binding protein [Rattus norvegicus]
Length = 351
Score = 89.4 bits (220), Expect = 2e-16
Identities = 115/375 (30%), Positives = 155/375 (41%), Gaps = 64/375 (17%)
Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
MAEN+++ GPP D TDFGSLFDLE+DLPDELI + EL L N G+
Sbjct: 1 MAENLLD-GPP--NPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGELSLLNSGN 57
Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQA--------MASQACQNS 112
+V DAASKHKQLSELLR GS ++ G+G + +Q NS
Sbjct: 58 ---------LVPDAASKHKQLSELLRGGSGSSITPGIGNVSASSPVQQGLGGQAQGQPNS 108
Query: 113 PGLSLINSMVKSPMACTGLTSPNM---GIGSSGPNQGPTQS------------------- 150
++ + +M KSP+ ++P++ +SGP +Q+
Sbjct: 109 TSMASLGAMGKSPLNPGDSSTPSLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATS 168
Query: 151 ---PAGMMNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSI--GAGRGRPN 205
P MN+ NQ G QVMNGS+
Sbjct: 169 QTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQA------QVMNGSLGAAGRGRGAG 222
Query: 206 MQYPNAGM-GNAGSLLTE---XXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQN 261
M YP M G S+L E KMGM N SP+G P++Q
Sbjct: 223 MPYPAPAMQGATSSVLAETLTQVSPQMAGHAGLNTAQAGGMTKMGMTGNTSPFGQPFSQT 282
Query: 262 SGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPVA 321
GQ +GA+G+ Q+ +K + N+L F D K S Q + A
Sbjct: 283 GGQPMGATGVNPQLASKQSMVNSLPAFPTDIKNT------SVTTVPNMSQLQTSVGIVPA 336
Query: 322 AGMGSGAHTADPEKR 336
G+ +G TADPEKR
Sbjct: 337 QGIATGP-TADPEKR 350
>gi|9368432|emb|CAB98139.1| MOZ/CBP protein [Homo sapiens]
Length = 376
Score = 89.0 bits (219), Expect = 2e-16
Identities = 97/305 (31%), Positives = 135/305 (44%), Gaps = 55/305 (18%)
Query: 29 DGTDFGSLFDLEHDLPDELI-NSTELGLTNGGDSSQLQTSLGIVQDAASKHKQLSELLRS 87
D DFGSLFDLE+DLPDELI N ELGL N G+ +V DAASKHKQLSELLR
Sbjct: 60 DADDFGSLFDLENDLPDELIPNGGELGLLNSGN---------LVPDAASKHKQLSELLRG 110
Query: 88 GSSPNLNMGVGGPGQA--------MASQACQNSPGLSLINSMVKSPMACTGLTSPNM--- 136
GS ++N G+G + +Q NS ++ +++M KSP++ ++P++
Sbjct: 111 GSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQ 170
Query: 137 GIGSSGPNQGPTQS----------------------PAGMMNSPVNQXXXXXXXXXXXXX 174
+SGP +Q+ P MN+ NQ
Sbjct: 171 AASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNSGHS 230
Query: 175 XXXXLAAGNGQGIMPNQVMNGSI--GAGRGRPNMQYPNAGM-GNAGSLLTE---XXXXXX 228
+ G QVMNGS+ M YP M G + S+L E
Sbjct: 231 LINQASQGQA------QVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQM 284
Query: 229 XXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPF 288
KMG+ N SP+G P++Q GQ +GA+G+ Q+ +K + N+L F
Sbjct: 285 TGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTF 344
Query: 289 AMDKK 293
D K
Sbjct: 345 PTDIK 349
>gi|17551090|ref|NP_510006.1| CREB-binding protein like family member (XM605) [Caenorhabditis
elegans]
gi|7497672|pir||T20071 hypothetical protein C49F5.5 - Caenorhabditis elegans
gi|3875065|emb|CAB03976.1| Hypothetical protein C49F5.5 [Caenorhabditis elegans]
Length = 151
Score = 86.7 bits (213), Expect = 1e-15
Identities = 35/97 (36%), Positives = 56/97 (57%), Gaps = 9/97 (9%)
Query: 332 DPEKRNVIQQQLVLLLHAHKCQRREQANGEVR---------QCNLPHCRTMKNVLNHMTH 382
DP VI++QL+LLLHA+ C +R++ N + +C+LP C K L+H+
Sbjct: 47 DPHILKVIKEQLILLLHANVCTKRDRENYQAAINGQPARHPRCDLPSCGLFKYTLSHLNM 106
Query: 383 CQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 419
C +G C + +C +S+Q+I HW+ C C +C PL+
Sbjct: 107 CTNGSHCLIDYCNTSKQLIKHWRECQNRACAICAPLR 143
>gi|17552402|ref|NP_497144.1| CREB-binding protein like family member (3A733) [Caenorhabditis
elegans]
gi|7496697|pir||T33579 hypothetical protein C29F9.6 - Caenorhabditis elegans
gi|3790688|gb|AAC68748.1| Hypothetical protein C29F9.6 [Caenorhabditis elegans]
Length = 228
Score = 70.1 bits (170), Expect = 1e-10
Identities = 26/52 (50%), Positives = 32/52 (61%)
Query: 364 QCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVC 415
QC +P C TMK V+ HM C +G C HC SSR +I HW CT +CP+C
Sbjct: 37 QCPVPQCSTMKEVIGHMMTCWNGFQCPSEHCTSSRMVIHHWTRCTNAECPIC 88
Score = 38.5 bits (88), Expect = 0.44
Identities = 26/112 (23%), Positives = 49/112 (43%), Gaps = 10/112 (8%)
Query: 548 NAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRME 607
N S P+ +P G + WH ++ + R ++ ++ + I P +R E
Sbjct: 96 NMNALSTIPIVKDPEPRPPGTSQPWHSEVPKTDREAVIERISKHIMLHP-------QRFE 148
Query: 608 ---NLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQ 656
+ AR E ++E+A +R EYY ++ E+ + Q + E QK+
Sbjct: 149 PIWKIKEDARAAELQIFEAAGSRDEYYRMVEERAPREQDKAPEGPGQEAQKE 200
>gi|12718195|emb|CAC28863.1| MORF/CBP protein [Homo sapiens]
Length = 141
Score = 67.4 bits (163), Expect = 9e-10
Identities = 40/64 (62%), Positives = 46/64 (71%), Gaps = 10/64 (15%)
Query: 32 DFGSLFDLEHDLPDELI-NSTELGLTNGGDSSQLQTSLGIVQDAASKHKQLSELLRSGSS 90
+FGSLFDLE+DLPDELI N ELGL N G+ +V DAASKHKQLSELLR GS
Sbjct: 87 NFGSLFDLENDLPDELIPNGGELGLLNSGN---------LVPDAASKHKQLSELLRGGSG 137
Query: 91 PNLN 94
++N
Sbjct: 138 SSIN 141
>gi|21105780|gb|AAM34788.1|AF512558_2 HAC5 [Arabidopsis thaliana]
Length = 1012
Score = 62.4 bits (150), Expect = 3e-08
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 7/85 (8%)
Query: 343 LVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIIS 402
L+ LLH KC E C +C T K +L H+ C++ +C +C +RQ+I
Sbjct: 94 LLFLLHVRKCNAAED------NCESKYCFTAKTLLKHINCCKA-PACAYQYCHQTRQLIH 146
Query: 403 HWKNCTRHDCPVCLPLKNAGDKRNQ 427
H+K+C CPVC+ +KN +K+ +
Sbjct: 147 HYKHCGDEACPVCVFVKNFKEKQKE 171
>gi|15230656|ref|NP_187904.1| CREB-binding protein -related [Arabidopsis thaliana]
gi|15795129|dbj|BAB02507.1| CREB-binding protein-like [Arabidopsis thaliana]
Length = 1670
Score = 59.7 bits (143), Expect = 2e-07
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 7/85 (8%)
Query: 343 LVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIIS 402
L+ LLH KC E C +C T K +L H+ C++ +C +C +RQ+I
Sbjct: 622 LLFLLHVRKCNAAED------NCESKYCFTAKTLLKHINCCKA-PACAYQYCHQTRQLIH 674
Query: 403 HWKNCTRHDCPVCLPLKNAGDKRNQ 427
H+K+C CPVC+ +KN +K+ +
Sbjct: 675 HYKHCGDEACPVCVFVKNFKEKQKE 699
>gi|21466092|pdb|1LIQ|A Chain A, Non-Native Solution Structure Of A Fragment Of The Ch1
Domain Of Cbp
Length = 27
Score = 58.5 bits (140), Expect = 4e-07
Identities = 24/27 (88%), Positives = 26/27 (96%)
Query: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGK 387
EVR C+LPHCRTMKNVLNHMTHCQ+GK
Sbjct: 1 EVRACSLPHCRTMKNVLNHMTHCQAGK 27
>gi|17508323|ref|NP_493339.1| CREB-binding protein like family member (80.3 kD) (1N890)
[Caenorhabditis elegans]
gi|7505888|pir||T23651 hypothetical protein M01E5.6 - Caenorhabditis elegans
gi|3878635|emb|CAB07643.1| Hypothetical protein M01E5.6 [Caenorhabditis elegans]
gi|3879438|emb|CAB03290.1| Hypothetical protein M01E5.6 [Caenorhabditis elegans]
Length = 702
Score = 55.1 bits (131), Expect = 4e-06
Identities = 30/96 (31%), Positives = 54/96 (56%), Gaps = 4/96 (4%)
Query: 566 TGIRKQWHEDITQDLRNHLVHKLVQAIFP-TPDPAALKDRRMENLVAYARKVEGDMYESA 624
T K+W I +D+RNH+V KL++A +P + + + L+A ARK E ++ E++
Sbjct: 596 TNTSKEW---IVEDIRNHMVGKLLKAFWPRIQNVEEMNGELFKKLIANARKCETEILEAS 652
Query: 625 NNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660
N+R EYY L+ + +I K+ +K + + + P
Sbjct: 653 NDRDEYYRLMQLTVDQILKKTLKKDQRATEHNHQQP 688
>gi|7487910|pir||T01055 hypothetical protein YUP8H12R.38 - Arabidopsis thaliana
gi|3152587|gb|AAC17068.1| Similar to CREB-binding protein homolog gb|U88570 from D.
melanogaster and contains similarity to
callus-associated protein gb|U01961 from Nicotiana
tabacum. EST gb|W43427 comes from this gene.
[Arabidopsis thaliana]
Length = 1516
Score = 54.3 bits (129), Expect = 8e-06
Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 8/101 (7%)
Query: 319 PVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLN 378
P A +G DP +N Q+ L+ L HA C+ E +C +C T++ +
Sbjct: 498 PTATTCRNGNGNRDPRFKNQ-QKWLLFLRHARHCKAPEG------KCPDRNCVTVQKLWK 550
Query: 379 HMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 419
HM C + C C ++ +I+H ++C +CPVC+P+K
Sbjct: 551 HMDSC-AAPQCSYPRCLPTKTLINHHRSCKEPNCPVCIPVK 590
>gi|18412221|ref|NP_565197.1| p300/CBP acetyltransferase-related protein 2 [Arabidopsis thaliana]
gi|12597461|gb|AAG60059.1| p300/CBP acetyltransferase-related protein 2 [Arabidopsis thaliana]
Length = 1654
Score = 53.9 bits (128), Expect = 1e-05
Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 8/101 (7%)
Query: 319 PVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLN 378
P A +G DP +N Q+ L+ L HA C+ E +C +C T++ +
Sbjct: 612 PTATTCRNGNGNRDPRFKNQ-QKWLLFLRHARHCKAPEG------KCPDRNCVTVQKLWK 664
Query: 379 HMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 419
HM C + C C ++ +I+H ++C +CPVC+P+K
Sbjct: 665 HMDSC-AAPQCSYPRCLPTKTLINHHRSCKEPNCPVCIPVK 704
>gi|25518555|pir||E86302 hypothetical protein F17F16.8 [imported] - Arabidopsis thaliana
gi|9954734|gb|AAG09087.1|AC026237_8 Unknown Protein [Arabidopsis thaliana]
Length = 1498
Score = 52.8 bits (125), Expect = 2e-05
Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 8/95 (8%)
Query: 332 DPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQV 391
DP+ +N Q+ L+ L HA C+ G +C +C T++ + +HM +C + C
Sbjct: 430 DPKFKNQ-QRWLLFLRHARSCK---PPGG---RCQDQNCVTVQKLWSHMDNC-ADPQCLY 481
Query: 392 AHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRN 426
C ++ +I H+KNC CPVC+P+K + N
Sbjct: 482 PRCRHTKALIGHYKNCKDPRCPVCVPVKTYQQQAN 516
>gi|17567279|ref|NP_509376.1| CREB-binding protein like (XI780) [Caenorhabditis elegans]
gi|7499689|pir||T16139 hypothetical protein F22F1.3 - Caenorhabditis elegans
gi|1118044|gb|AAA83283.1| Hypothetical protein F22F1.3 [Caenorhabditis elegans]
Length = 295
Score = 52.0 bits (123), Expect = 4e-05
Identities = 23/72 (31%), Positives = 42/72 (58%)
Query: 576 ITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLA 635
IT+ +R H++ KL +FP PD A D RM+ ++ R +E + + + +YY+L +
Sbjct: 187 ITRRIRIHVIDKLGLMLFPAPDQNAYYDGRMDRIIRKLRNLEAEAFRECIDCDDYYNLAS 246
Query: 636 EKIYKIQKELEE 647
K YK+ K +++
Sbjct: 247 IKAYKLHKTMKK 258
Score = 48.9 bits (115), Expect = 3e-04
Identities = 24/73 (32%), Positives = 38/73 (52%)
Query: 576 ITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLA 635
+ + LR +++ K+V+ P P+ A D RM L YA +E +E + EYY LA
Sbjct: 66 LERGLRQYMITKIVREAVPRPNSDAKNDARMIELKEYATFMEKKSFEKVQTKDEYYAELA 125
Query: 636 EKIYKIQKELEEK 648
I +QK L+ +
Sbjct: 126 RIILSMQKHLQSR 138
>gi|15219327|ref|NP_173115.1| expressed protein [Arabidopsis thaliana]
Length = 1706
Score = 52.0 bits (123), Expect = 4e-05
Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 8/95 (8%)
Query: 332 DPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQV 391
DP+ +N Q+ L+ L HA C+ G +C +C T++ + +HM +C + C
Sbjct: 638 DPKFKNQ-QRWLLFLRHARSCK---PPGG---RCQDQNCVTVQKLWSHMDNC-ADPQCLY 689
Query: 392 AHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRN 426
C ++ +I H+KNC CPVC+P+K + N
Sbjct: 690 PRCRHTKALIGHYKNCKDPRCPVCVPVKTYQQQAN 724
>gi|7489105|pir||T02019 callus-associated protein - common tobacco (fragment)
gi|432982|gb|AAA03633.1| callus associated protein
Length = 670
Score = 47.0 bits (110), Expect = 0.001
Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 9/89 (10%)
Query: 333 PEKRNVIQQQ--LVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQ 390
P +R + Q+ L+ L+HA +C E +C +C + +L HM C C
Sbjct: 468 PRERQYLNQKRWLLFLIHARRCSAPEG------KCPENNCIHAQKLLRHMERCIK-FDCP 520
Query: 391 VAHCASSRQIISHWKNCTRHDCPVCLPLK 419
C ++ +I+H K+C +CPVC+P+K
Sbjct: 521 YPRCPETKVLINHHKHCKNENCPVCIPVK 549
>gi|11514507|pdb|1F81|A Chain A, Solution Structure Of The Taz2 Domain Of The
Transcriptional Adaptor Protein Cbp
Length = 88
Score = 42.7 bits (99), Expect = 0.024
Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 17/92 (18%)
Query: 335 KRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHC 394
+R IQ+ + L+HA +C+ AN C+LP C+ MK V+ H C+ + C
Sbjct: 7 RRLSIQRCIQSLVHACQCR---NAN-----CSLPSCQKMKRVVQHTKGCKRKTN---GGC 55
Query: 395 ASSRQIIS----HWKNCTRHDCPV--CLPLKN 420
+Q+I+ H K+C + CPV CL +K+
Sbjct: 56 PVCKQLIALCCYHAKHCQENKCPVPFCLNIKH 87
>gi|6056385|gb|AAF02849.1|AC009894_20 Unknown protein [Arabidopsis thaliana]
Length = 1209
Score = 37.7 bits (86), Expect = 0.72
Identities = 17/88 (19%), Positives = 40/88 (45%), Gaps = 7/88 (7%)
Query: 337 NVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCAS 396
N + + + + HA C+ ++ +C C + ++ H+ C+ +C+ +C
Sbjct: 421 NTVLRWIPFMFHARHCKAKKD------KCASKFCFQARKIVKHIDCCKV-PNCKYRYCLG 473
Query: 397 SRQIISHWKNCTRHDCPVCLPLKNAGDK 424
+R + H+K C C C+ ++ +K
Sbjct: 474 TRMWLDHFKQCKSISCRTCVAVREYMEK 501
>gi|14794966|gb|AAK73519.1| HAC4 [Arabidopsis thaliana]
Length = 413
Score = 37.4 bits (85), Expect = 0.85
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 9/76 (11%)
Query: 348 HAHKCQRRE--------QANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQ 399
H+HK R Q NG+ Q +K +L H C+S + CQ C S+
Sbjct: 278 HSHKLTSRSSSTDSTVVQQNGQASQSYQVKLEKLKKLLVHAATCRSTQ-CQYQGCRKSKM 336
Query: 400 IISHWKNCTRHDCPVC 415
+ H +CT DCP+C
Sbjct: 337 LFRHCIDCTTGDCPIC 352
>gi|21105785|gb|AAM34790.1|AF512560_2 HAC4 [Arabidopsis thaliana]
Length = 385
Score = 37.4 bits (85), Expect = 0.96
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 9/76 (11%)
Query: 348 HAHKCQRRE--------QANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQ 399
H+HK R Q NG+ Q +K +L H C+S + CQ C S+
Sbjct: 250 HSHKLTSRSSSTDSTVVQQNGQASQSYQVKLEKLKKLLVHAATCRSTQ-CQYQGCRKSKM 308
Query: 400 IISHWKNCTRHDCPVC 415
+ H +CT DCP+C
Sbjct: 309 LFRHCIDCTTGDCPIC 324