>gi|547239|gb|AAB31182.1| p300=transcription coactivator {N-terminal} [mice, Peptide Partial, 688 aa] Length = 688 Score = 1018 bits (2633), Expect = 0.0 Identities = 594/688 (86%), Positives = 594/688 (86%) Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60 MAENVVEPGPP DGTDFGSLFDLEHDLPDELINSTELGLTNGGD Sbjct: 1 MAENVVEPGPPSAKRLKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60 Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQACQNSPGLSLINS 120 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQACQNSPGLSLINS Sbjct: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQACQNSPGLSLINS 120 Query: 121 MVKSPMACTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQXXXXXXXXXXXXXXXXXLA 180 MVKSPMACTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQ LA Sbjct: 121 MVKSPMACTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQPAMGMNTGMNAGMNPGMLA 180 Query: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEXXXXXXXXXXXXXXXXXX 240 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTE Sbjct: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEPLQQGSPQMGGQPGLRGP 240 Query: 241 XXLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXX 300 LKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAV Sbjct: 241 QPLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVPGGGM 300 Query: 301 XXXXXXXXXSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANG 360 SVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANG Sbjct: 301 PSMGQQPTPSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANG 360 Query: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN Sbjct: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420 Query: 421 AGDKRNQCSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXX 480 AGDKRNQCSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGL Sbjct: 421 AGDKRNQCSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQ 480 Query: 481 XXXXXXXXAKNXXXXXXXXXXXXMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS 540 AKN MRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS Sbjct: 481 IPPQPQVQAKNQQSQPSGQSPQGMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS 540 Query: 541 QNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 600 QNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA Sbjct: 541 QNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 600 Query: 601 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP Sbjct: 601 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660 Query: 661 NAPGMGPVPMNTGSNMGQQPTGMTTNGP 688 NAPGMGPVPMNTGSNMGQQPTGMTTNGP Sbjct: 661 NAPGMGPVPMNTGSNMGQQPTGMTTNGP 688
>gi|28486616|ref|XP_283295.1| similar to E1A-associated protein p300 [Mus musculus] gi|29244384|ref|NP_808489.1| hypothetical protein A730011L11 [Mus musculus] gi|26335221|dbj|BAC31311.1| unnamed protein product [Mus musculus] Length = 714 Score = 974 bits (2517), Expect = 0.0 Identities = 587/688 (85%), Positives = 588/688 (85%) Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60 MAENVVEPGPP DGTDFGSLFDLEHDLPDELINSTELGLTNGGD Sbjct: 1 MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60 Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQACQNSPGLSLINS 120 SQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQA QNSPGLSLINS Sbjct: 61 ISQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQAQQNSPGLSLINS 120 Query: 121 MVKSPMACTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQXXXXXXXXXXXXXXXXXLA 180 MVKSPMA TGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQ LA Sbjct: 121 MVKSPMAQTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQPAMGMNTGMNAGMNPGMLA 180 Query: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEXXXXXXXXXXXXXXXXXX 240 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTE Sbjct: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEPLQQGSPQMGGQPGLRGP 240 Query: 241 XXLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXX 300 LKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAV Sbjct: 241 QPLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVPGGGM 300 Query: 301 XXXXXXXXXSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANG 360 SVQQPGLVTPVAAGMGSGAHTADPEKR +IQQQLVLLLHAHKCQRREQANG Sbjct: 301 PSMGQQPTPSVQQPGLVTPVAAGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANG 360 Query: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN Sbjct: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420 Query: 421 AGDKRNQCSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXX 480 AGDKRNQ SILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGL Sbjct: 421 AGDKRNQQSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQ 480 Query: 481 XXXXXXXXAKNXXXXXXXXXXXXMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS 540 AKN MRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS Sbjct: 481 IPPQPQVQAKNQQSQPSGQSPQGMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS 540 Query: 541 QNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 600 QNPMMS NAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA Sbjct: 541 QNPMMSENAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 600 Query: 601 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP Sbjct: 601 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660 Query: 661 NAPGMGPVPMNTGSNMGQQPTGMTTNGP 688 NAPGMGPVPMNTGSNMGQQPTGMTTNGP Sbjct: 661 NAPGMGPVPMNTGSNMGQQPTGMTTNGP 688
>gi|31753089|gb|AAH53889.1| Unknown (protein for IMAGE:6151364) [Homo sapiens] Length = 1553 Score = 959 bits (2480), Expect = 0.0 Identities = 546/688 (79%), Positives = 562/688 (81%), Gaps = 1/688 (0%) Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60 MAENVVEPGPP DGTDFGSLFDLEHDLPDELINSTELGLTNGGD Sbjct: 1 MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60 Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQACQNSPGLSLINS 120 +QLQTSLG+VQDAASKHKQLSELLRSGSSPNLNMGVGGPGQ MASQA Q+SPGL LINS Sbjct: 61 INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS 120 Query: 121 MVKSPMACTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQXXXXXXXXXXXXXXXXXLA 180 MVKSPM GLTSPNMG+G+SGPNQGPTQS GMMNSPVNQ LA Sbjct: 121 MVKSPMTQAGLTSPNMGMGTSGPNQGPTQS-TGMMNSPVNQPAMGMNTGMNAGMNPGMLA 179 Query: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEXXXXXXXXXXXXXXXXXX 240 AGNGQGIMPNQVMNGSIGAGRGR NMQYPN GMG+AG+LLTE Sbjct: 180 AGNGQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGP 239 Query: 241 XXLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXX 300 LKMGMMNNP+PYGSPYTQN GQQIGASGLGLQIQTKTVL NNLSPFAMDKKAV Sbjct: 240 QPLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGM 299 Query: 301 XXXXXXXXXSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANG 360 VQQPGLVTPVA GMGSGAHTADPEKR +IQQQLVLLLHAHKCQRREQANG Sbjct: 300 PNMGQQPAPQVQQPGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANG 359 Query: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN Sbjct: 360 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 419 Query: 421 AGDKRNQCSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXX 480 AGDKRNQ ILTGAPVGLGNPSSLGVGQQS P+LSTVSQIDPSSIERAYAALGL Sbjct: 420 AGDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQ 479 Query: 481 XXXXXXXXAKNXXXXXXXXXXXXMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS 540 AKN MR ++NMSASPMGVNGGVGVQTP+LLSDSMLHS INS Sbjct: 480 MPTQPQVQAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINS 539 Query: 541 QNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 600 QNPMMS NA V SLGP+PTAAQPS+TGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA Sbjct: 540 QNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 599 Query: 601 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP Sbjct: 600 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 659 Query: 661 NAPGMGPVPMNTGSNMGQQPTGMTTNGP 688 NA GM PV MN G NMGQ GMT+NGP Sbjct: 660 NAAGMVPVSMNPGPNMGQPQPGMTSNGP 687
>gi|4557557|ref|NP_001420.1| E1A binding protein p300; E1A-binding protein, 300kD [Homo sapiens] gi|3024341|sp|Q09472|P300_HUMAN E1A-associated protein p300 gi|627657|pir||A54277 transcription adaptor protein p300 - human gi|495301|gb|AAA18639.1| p300 protein Length = 2414 Score = 942 bits (2435), Expect = 0.0 Identities = 545/688 (79%), Positives = 562/688 (81%), Gaps = 1/688 (0%) Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60 MAENVVEPGPP DGTDFGSLFDLEHDLPDELINSTELGLTNGGD Sbjct: 1 MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60 Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQACQNSPGLSLINS 120 +QLQTSLG+VQDAASKHKQLSELLRSGSSPNLNMGVGGPGQ MASQA Q+SPGL LINS Sbjct: 61 INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS 120 Query: 121 MVKSPMACTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQXXXXXXXXXXXXXXXXXLA 180 MVKSPM GLTSPNMG+G+SGPNQGPTQS GMMNSPVNQ LA Sbjct: 121 MVKSPMTQAGLTSPNMGMGTSGPNQGPTQS-TGMMNSPVNQPAMGMNTGTNAGMNPGMLA 179 Query: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEXXXXXXXXXXXXXXXXXX 240 AGNGQGIMPNQVMNGSIGAGRGR +MQYPN GMG+AG+LLTE Sbjct: 180 AGNGQGIMPNQVMNGSIGAGRGRQDMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGP 239 Query: 241 XXLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXX 300 LKMGMMNNP+PYGSPYTQN GQQIGASGLGLQIQTKTVL NNLSPFAMDKKAV Sbjct: 240 QPLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGM 299 Query: 301 XXXXXXXXXSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANG 360 VQQPGLVTPVA GMGSGAHTADPEKR +IQQQLVLLLHAHKCQRREQANG Sbjct: 300 PNMGQQPAPQVQQPGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANG 359 Query: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN Sbjct: 360 EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 419 Query: 421 AGDKRNQCSILTGAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXX 480 AGDKRNQ ILTGAPVGLGNPSSLGVGQQS P+LSTVSQIDPSSIERAYAALGL Sbjct: 420 AGDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQ 479 Query: 481 XXXXXXXXAKNXXXXXXXXXXXXMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINS 540 AKN MR ++NMSASPMGVNGGVGVQTP+LLSDSMLHS INS Sbjct: 480 MPTQPQVQAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINS 539 Query: 541 QNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 600 QNPMMS NA V SLGP+PTAAQPS+TGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA Sbjct: 540 QNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA 599 Query: 601 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP Sbjct: 600 LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 659 Query: 661 NAPGMGPVPMNTGSNMGQQPTGMTTNGP 688 NA GM PV MN G NMGQ GMT+NGP Sbjct: 660 NAAGMVPVSMNPGPNMGQPQPGMTSNGP 687
>gi|27666550|ref|XP_235770.1| similar to E1A-associated protein p300 [Rattus norvegicus] Length = 1605 Score = 532 bits (1371), Expect = e-150 Identities = 278/313 (88%), Positives = 281/313 (89%) Query: 373 MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILT 432 MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQ SILT Sbjct: 1 MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQSILT 60 Query: 433 GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNX 492 GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGL AKN Sbjct: 61 GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQIPPQPPVQAKNQ 120 Query: 493 XXXXXXXXXXXMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMMSGNAGVA 552 MRS+NNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMM+ NA VA Sbjct: 121 QSQPSGQSPQGMRSMNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMMNENASVA 180 Query: 553 SLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY 612 SLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY Sbjct: 181 SLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY 240 Query: 613 ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGMGPVPMNT 672 ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP+APGM PVPMNT Sbjct: 241 ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPSAPGMVPVPMNT 300 Query: 673 GSNMGQQPTGMTT 685 NMGQQPTGMTT Sbjct: 301 APNMGQQPTGMTT 313
Score = 37.7 bits (86), Expect = 0.65 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 15/84 (17%) Query: 335 KRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHC 394 +R IQ+ + L+HA +C+ AN C+LP C+ MK V+ H C+ + C Sbjct: 1202 RRLSIQRCIQSLVHACQCR---NAN-----CSLPSCQKMKRVVQHTKGCKRKTN---GGC 1250 Query: 395 ASSRQIIS----HWKNCTRHDCPV 414 +Q+I+ H K+C + CPV Sbjct: 1251 PICKQLIALCCYHAKHCQENKCPV 1274
>gi|27663074|ref|XP_235502.1| similar to E1A-associated protein p300 [Rattus norvegicus] Length = 2156 Score = 517 bits (1331), Expect = e-145 Identities = 278/313 (88%), Positives = 281/313 (89%) Query: 373 MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILT 432 MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQ SILT Sbjct: 1 MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQSILT 60 Query: 433 GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNX 492 GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGL AKN Sbjct: 61 GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQIPPQPPVQAKNQ 120 Query: 493 XXXXXXXXXXXMRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMMSGNAGVA 552 MRS+NNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMM+ NA VA Sbjct: 121 QSQPSGQSPQGMRSMNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMMNENASVA 180 Query: 553 SLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY 612 SLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY Sbjct: 181 SLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAY 240 Query: 613 ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGMGPVPMNT 672 ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP+APGM PVPMNT Sbjct: 241 ARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPSAPGMVPVPMNT 300 Query: 673 GSNMGQQPTGMTT 685 NMGQQPTGMTT Sbjct: 301 APNMGQQPTGMTT 313
>gi|4758056|ref|NP_004371.1| CREB binding protein [Homo sapiens] gi|3023440|sp|Q92793|CBP_HUMAN CREB-binding protein gi|2443859|gb|AAC51770.1| CREB-binding protein Length = 2442 Score = 474 bits (1220), Expect = e-132 Identities = 340/735 (46%), Positives = 418/735 (56%), Gaps = 75/735 (10%) Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG 59 MAEN+++ GPP D TDFGSLFDLE+DLPDELI N ELGL N G Sbjct: 1 MAENLLD-GPP--NPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSG 57 Query: 60 DSSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQA--------MASQACQN 111 + +V DAASKHKQLSELLR GS ++N G+G + +Q N Sbjct: 58 N---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN 108 Query: 112 SPGLSLINSMVKSPMACTGLTSPNM---GIGSSGPNQGPTQS------------------ 150 S ++ +++M KSP++ ++P++ +SGP +Q+ Sbjct: 109 SANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT 168 Query: 151 ----PAGMMNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSI--GAGRGRP 204 P MN+ NQ + G QVMNGS+ Sbjct: 169 SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQA------QVMNGSLGAAGRGRGA 222 Query: 205 NMQYPNAGM-GNAGSLLTE---XXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQ 260 M YP M G + S+L E KMG+ N SP+G P++Q Sbjct: 223 GMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQ 282 Query: 261 NSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPV 320 GQ +GA+G+ Q+ +K + N+L F D K G+V Sbjct: 283 AGGQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQ----TSVGIVPTQ 338 Query: 321 AAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHM 380 A G TADPEKR +IQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHM Sbjct: 339 AIATGP---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHM 395 Query: 381 THCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGN 440 THCQ+GK+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQ +IL G+ N Sbjct: 396 THCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQN 455 Query: 441 P-SSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNXXXXXXXX 499 S+G GQQ+ SLS + IDPSS++RAYAALGL Sbjct: 456 TIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQ--QPAQPQ 513 Query: 500 XXXXMRSVNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINSQNPMM---SGNAGVAS 553 MR++N + +PM + G Q PNL+S+S L +++ + NP+M S + + + Sbjct: 514 THQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGT 573 Query: 554 LGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYA 613 L +PTAA PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA Sbjct: 574 LSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYA 633 Query: 614 RKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGMGPVPMNTG 673 +KVEGDMYESAN+R EYYHLLAEKIYKIQKELEEKRR+RL KQ +L N P + P P Sbjct: 634 KKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPAL-PAPGAQP 692 Query: 674 SNMGQQPTGMTTNGP 688 + Q NGP Sbjct: 693 PVIPQAQPVRPPNGP 707
>gi|4321116|gb|AAC51331.2| CREB-binding protein [Homo sapiens] Length = 2442 Score = 474 bits (1220), Expect = e-132 Identities = 340/735 (46%), Positives = 418/735 (56%), Gaps = 75/735 (10%) Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG 59 MAEN+++ GPP D TDFGSLFDLE+DLPDELI N ELGL N G Sbjct: 1 MAENLLD-GPP--NPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSG 57 Query: 60 DSSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQA--------MASQACQN 111 + +V DAASKHKQLSELLR GS ++N G+G + +Q N Sbjct: 58 N---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN 108 Query: 112 SPGLSLINSMVKSPMACTGLTSPNM---GIGSSGPNQGPTQS------------------ 150 S ++ +++M KSP++ ++P++ +SGP +Q+ Sbjct: 109 SANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT 168 Query: 151 ----PAGMMNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSI--GAGRGRP 204 P MN+ NQ + G QVMNGS+ Sbjct: 169 SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQA------QVMNGSLGAAGRGRGA 222 Query: 205 NMQYPNAGM-GNAGSLLTE---XXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQ 260 M YP M G + S+L E KMG+ N SP+G P++Q Sbjct: 223 GMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQ 282 Query: 261 NSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPV 320 GQ +GA+G+ Q+ +K + N+L F D K G+V Sbjct: 283 AGGQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQ----TSVGIVPTQ 338 Query: 321 AAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHM 380 A G TADPEKR +IQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHM Sbjct: 339 AIATGP---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHM 395 Query: 381 THCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGN 440 THCQ+GK+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQ +IL G+ N Sbjct: 396 THCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQN 455 Query: 441 P-SSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNXXXXXXXX 499 S+G GQQ+ SLS + IDPSS++RAYAALGL Sbjct: 456 TIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQ--QPAQPQ 513 Query: 500 XXXXMRSVNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINSQNPMM---SGNAGVAS 553 MR++N + +PM + G Q PNL+S+S L +++ + NP+M S + + + Sbjct: 514 THQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGT 573 Query: 554 LGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYA 613 L +PTAA PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA Sbjct: 574 LSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYA 633 Query: 614 RKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGMGPVPMNTG 673 +KVEGDMYESAN+R EYYHLLAEKIYKIQKELEEKRR+RL KQ +L N P + P P Sbjct: 634 KKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPAL-PAPGAQP 692 Query: 674 SNMGQQPTGMTTNGP 688 + Q NGP Sbjct: 693 PVIPQAQPVRPPNGP 707
>gi|1345703|sp|P45481|CBP_MOUSE CREB-binding protein gi|481698|pir||S39161 CREB-binding protein - mouse gi|435855|gb|AAB28651.1| CREB-binding protein; CBP [Mus sp.] Length = 2441 Score = 473 bits (1216), Expect = e-132 Identities = 336/711 (47%), Positives = 405/711 (56%), Gaps = 73/711 (10%) Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60 MAEN+++ GPP D TDFGSLFDLE+DLPDELI + EL L N G+ Sbjct: 1 MAENLLD-GPP--NPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIPNGELSLLNSGN 57 Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQA--------MASQACQNS 112 +V DAASKHKQLSELLR GS ++N G+G + +Q NS Sbjct: 58 ---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNS 108 Query: 113 PGLSLINSMVKSPMACTGLTSPNM---GIGSSGPNQGPTQS------------------- 150 ++ + +M KSP+ ++PN+ +SGP +Q+ Sbjct: 109 TNMASLGAMGKSPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATS 168 Query: 151 ---PAGMMNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSI--GAGRGRPN 205 P MN+ NQ G QVMNGS+ Sbjct: 169 QTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQA------QVMNGSLGAAGRGRGAG 222 Query: 206 MQYPNAGM-GNAGSLLTE---XXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQN 261 M YP M G S+L E KMGM SP+G P++Q Sbjct: 223 MPYPAPAMQGATSSVLAETLTQVSPQMAGHAGLNTAQAGGMTKMGMTGTTSPFGQPFSQT 282 Query: 262 SGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPVA 321 GQQ+GA+G+ Q+ +K + N+L F D K G+V A Sbjct: 283 GGQQMGATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMSQLQ----TSVGIVPTQA 338 Query: 322 AGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMT 381 G TADPEKR +IQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMT Sbjct: 339 IATGP---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMT 395 Query: 382 HCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGNP 441 HCQ+ K+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQ +IL G+ N Sbjct: 396 HCQAPKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNT 455 Query: 442 -SSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNXXXXXXXXX 500 S+G GQQ+ SLS + IDPSS++RAYAALGL Sbjct: 456 IGSVGAGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQ--QPAQPPA 513 Query: 501 XXXMRSVNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINSQNPMM---SGNAGVASL 554 MR++N + +PM V G Q PNL+S+S L +++ + NP+M S + + SL Sbjct: 514 HQQMRTLNALGNNPMSVPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGSL 573 Query: 555 GPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYAR 614 +PTAA PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+ Sbjct: 574 STIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAK 633 Query: 615 KVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGM 665 KVEGDMYESAN+R EYYHLLAEKIYKIQKELEEKRRTRL KQ +L N P + Sbjct: 634 KVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPAL 684
>gi|737920|prf||1923401A protein CBP Length = 2441 Score = 473 bits (1216), Expect = e-132 Identities = 336/711 (47%), Positives = 405/711 (56%), Gaps = 73/711 (10%) Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60 MAEN+++ GPP D TDFGSLFDLE+DLPDELI + EL L N G+ Sbjct: 1 MAENLLD-GPP--NPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIPNGELSLLNSGN 57 Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQA--------MASQACQNS 112 +V DAASKHKQLSELLR GS ++N G+G + +Q NS Sbjct: 58 ---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNS 108 Query: 113 PGLSLINSMVKSPMACTGLTSPNM---GIGSSGPNQGPTQS------------------- 150 ++ + +M KSP+ ++PN+ +SGP +Q+ Sbjct: 109 TNMASLGAMGKSPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATS 168 Query: 151 ---PAGMMNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSI--GAGRGRPN 205 P MN+ NQ G QVMNGS+ Sbjct: 169 QTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQA------QVMNGSLGAAGRGRGAG 222 Query: 206 MQYPNAGM-GNAGSLLTE---XXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQN 261 M YP M G S+L E KMGM SP+G P++Q Sbjct: 223 MPYPAPAMQGATSSVLAETLTQVSPQMAGHAGLNTAQAGGMTKMGMTGTTSPFGQPFSQT 282 Query: 262 SGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPVA 321 GQQ+GA+G+ Q+ +K + N+L F D K G+V A Sbjct: 283 GGQQMGATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMSQLQ----TSVGIVPTQA 338 Query: 322 AGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMT 381 G TADPEKR +IQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMT Sbjct: 339 IATGP---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMT 395 Query: 382 HCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGNP 441 HCQ+ K+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQ +IL G+ N Sbjct: 396 HCQAPKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNT 455 Query: 442 -SSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNXXXXXXXXX 500 S+G GQQ+ SLS + IDPSS++RAYAALGL Sbjct: 456 IGSVGAGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQ--QPAQPPA 513 Query: 501 XXXMRSVNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINSQNPMM---SGNAGVASL 554 MR++N + +PM V G Q PNL+S+S L +++ + NP+M S + + SL Sbjct: 514 HQQMRTLNALGNNPMSVPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGSL 573 Query: 555 GPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYAR 614 +PTAA PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+ Sbjct: 574 STIPTAAPPSSTGVRKGWHERVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAK 633 Query: 615 KVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGM 665 KVEGDMYESAN+R EYYHLLAEKIYKIQKELEEKRRTRL KQ +L N P + Sbjct: 634 KVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPAL 684
>gi|19547885|gb|AAL87531.1| CREB-binding protein [Mus musculus] gi|19547887|gb|AAL87532.1| CREB-binding protein [Mus musculus] Length = 2429 Score = 471 bits (1213), Expect = e-131 Identities = 328/683 (48%), Positives = 396/683 (57%), Gaps = 70/683 (10%) Query: 29 DGTDFGSLFDLEHDLPDELINSTELGLTNGGDSSQLQTSLGIVQDAASKHKQLSELLRSG 88 D TDFGSLFDLE+DLPDELI + EL L N G+ +V DAASKHKQLSELLR G Sbjct: 20 DNTDFGSLFDLENDLPDELIPNGELSLLNSGN---------LVPDAASKHKQLSELLRGG 70 Query: 89 SSPNLNMGVGGPGQA--------MASQACQNSPGLSLINSMVKSPMACTGLTSPNM---G 137 S ++N G+G + +Q NS ++ + +M KSP+ ++PN+ Sbjct: 71 SGSSINPGIGNVSASSPVQQGLGGQAQGQPNSTNMASLGAMGKSPLNQGDSSTPNLPKQA 130 Query: 138 IGSSGPNQGPTQS----------------------PAGMMNSPVNQXXXXXXXXXXXXXX 175 +SGP +Q+ P MN+ NQ Sbjct: 131 ASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSL 190 Query: 176 XXXLAAGNGQGIMPNQVMNGSI--GAGRGRPNMQYPNAGM-GNAGSLLTE---XXXXXXX 229 G QVMNGS+ M YP M G S+L E Sbjct: 191 MNQAQQGQA------QVMNGSLGAAGRGRGAGMPYPAPAMQGATSSVLAETLTQVSPQMA 244 Query: 230 XXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFA 289 KMGM SP+G P++Q GQQ+GA+G+ Q+ +K + N+L F Sbjct: 245 GHAGLNTAQAGGMTKMGMTGTTSPFGQPFSQTGGQQMGATGVNPQLASKQSMVNSLPAFP 304 Query: 290 MDKKAVXXXXXXXXXXXXXXSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHA 349 D K G+V A G TADPEKR +IQQQLVLLLHA Sbjct: 305 TDIKNTSVTTVPNMSQLQ----TSVGIVPTQAIATGP---TADPEKRKLIQQQLVLLLHA 357 Query: 350 HKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTR 409 HKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+GK+CQVAHCASSRQIISHWKNCTR Sbjct: 358 HKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTR 417 Query: 410 HDCPVCLPLKNAGDKRNQCSILTGAPVGLGNP-SSLGVGQQSTPSLSTVSQIDPSSIERA 468 HDCPVCLPLKNA DKRNQ +IL G+ N S+G GQQ+ SLS + IDPSS++RA Sbjct: 418 HDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSMQRA 477 Query: 469 YAALGLXXXXXXXXXXXXXXAKNXXXXXXXXXXXXMRSVNNMSASPMGVNGG---VGVQT 525 YAALGL MR++N + +PM + G Q Sbjct: 478 YAALGLPYMNQPQTQLQPQVPGQ--QPAQPPAHQQMRTLNALGNNPMSIPAGGITTDQQP 535 Query: 526 PNLLSDSMLHSTINSQNPMM---SGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRN 582 PNL+S+S L +++ + NP+M S + + SL +PTAA PSSTG+RK WHE +TQDLR+ Sbjct: 536 PNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLRS 595 Query: 583 HLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQ 642 HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGDMYESAN+R EYYHLLAEKIYKIQ Sbjct: 596 HLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQ 655 Query: 643 KELEEKRRTRLQKQNMLPNAPGM 665 KELEEKRR+RL KQ +L N P + Sbjct: 656 KELEEKRRSRLHKQGILGNQPAL 678
>gi|631119|pir||S39162 transcription coactivator CREB-binding protein - human Length = 2440 Score = 468 bits (1205), Expect = e-130 Identities = 339/735 (46%), Positives = 417/735 (56%), Gaps = 75/735 (10%) Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG 59 MAEN+++ GPP TDFGSLFDLE+DLPDELI N ELGL N G Sbjct: 1 MAENLLD-GPP--NPKRAKLSSPGFSANSNTDFGSLFDLENDLPDELIPNGGELGLLNSG 57 Query: 60 DSSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQA--------MASQACQN 111 + +V DAASKHKQLSELLR GS ++N G+G + +Q N Sbjct: 58 N---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN 108 Query: 112 SPGLSLINSMVKSPMACTGLTSPNM---GIGSSGPNQGPTQS------------------ 150 S ++ +++M KSP++ +SP++ +SGP +Q+ Sbjct: 109 SANMASLSAMGKSPLSQGDSSSPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT 168 Query: 151 ----PAGMMNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSIGAGRGRPNM 206 P MN+ NQ + G QVMNGS+GA Sbjct: 169 SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQA------QVMNGSLGAAGRGRGA 222 Query: 207 QYP---NAGMGNAGSLLTE---XXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQ 260 P A G + S+L E K+GM SP+G P++Q Sbjct: 223 GMPYTAPAMQGASSSVLAETLTQVSPQTAGHAGLNTAQAGGMAKIGMNGTTSPFGQPFSQ 282 Query: 261 NSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPV 320 GQ +GA+G+ Q+ +K + N+L F D K G+V Sbjct: 283 AGGQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQ----TSVGIVPTQ 338 Query: 321 AAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHM 380 A G TADPEKR +IQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHM Sbjct: 339 AIATGP---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHM 395 Query: 381 THCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGN 440 THCQ+GK+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQ +IL G+ N Sbjct: 396 THCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQN 455 Query: 441 P-SSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNXXXXXXXX 499 S+G GQQ+ SLS + IDPSS++RAYAALGL Sbjct: 456 TIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQ--QPAQPQ 513 Query: 500 XXXXMRSVNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINSQNPMM---SGNAGVAS 553 MR++N + +PM + G Q PNL+S+S L +++ + NP+M S + + + Sbjct: 514 THQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGT 573 Query: 554 LGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYA 613 L +PTAA PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA Sbjct: 574 LSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYA 633 Query: 614 RKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGMGPVPMNTG 673 +KVEGDMYESAN+R EYYHLLAEKIYKIQKELEEKRR+RL KQ +L N P + P P Sbjct: 634 KKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPAL-PAPGAQP 692 Query: 674 SNMGQQPTGMTTNGP 688 + Q + NGP Sbjct: 693 PVIPQAQSVRPPNGP 707
>gi|27881767|gb|AAH44677.1| Similar to CREB binding protein (Rubinstein-Taybi syndrome) [Xenopus laevis] Length = 1047 Score = 427 bits (1099), Expect = e-118 Identities = 349/731 (47%), Positives = 424/731 (58%), Gaps = 71/731 (9%) Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60 MAEN+++ GPP D TDF S FDLE+DLPDELI NGG+ Sbjct: 1 MAENLLD-GPP-NRKRPKLSSPGFSASTDSTDF-SFFDLENDLPDELI-------PNGGE 50 Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSP-NLNMGVGGPGQAM----ASQACQNSPGL 115 S L T + QDAAS+++QLS+LLR G++ MG G G + SQ Q+SPGL Sbjct: 51 LSILGTGGSLGQDAASQNRQLSDLLRGGNAGLGAAMGRGRSGSPVQQGLGSQGQQHSPGL 110 Query: 116 SLINSMVKSPM-------ACTGLTSPNMGIGSSGP-------------NQGPTQSPAGM- 154 + S+ KSP+ + GLT G S P + P+Q P G+ Sbjct: 111 GNLGSLNKSPLNQGLSVTSPAGLTKTTGTPGPSVPASQAQKQVSMVAGSTAPSQVPTGLC 170 Query: 155 MNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSIGAG-RGRPN-MQYPNAG 212 MNS NQ G QV+NGS+G G RGR +QY + Sbjct: 171 MNSNFNQGHQTLLNSNSGHTLMSQAQPAQG------QVLNGSLGVGSRGRGTALQYNSPA 224 Query: 213 M-GNAGSLLTE---XXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQNSGQQIGA 268 M N GS+L E KMG+ N SP+G + Q +GQQI A Sbjct: 225 MQTNPGSVLAETLTQGTATMPTHAGMTTAQTGAMNKMGLPGNTSPFGQTFNQAAGQQIRA 284 Query: 269 SGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPVAAGMGSGA 328 G+ Q+ K + N+L PF D K VQQ G+ T + G G Sbjct: 285 QGVSPQLPAKPAMANSLPPFPSDIKNA-PVANLPNMSPLQAQVQQVGIGTSPSMGTGP-- 341 Query: 329 HTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKS 388 TADPEKR +IQQQLVLLLHAHKCQRREQANGE+R C+LPHCRTMKNVLNHMTHCQ+GK+ Sbjct: 342 -TADPEKRKLIQQQLVLLLHAHKCQRREQANGEMRDCSLPHCRTMKNVLNHMTHCQAGKA 400 Query: 389 CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGNPSSLGVGQ 448 CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQ ++ A + G GQ Sbjct: 401 CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQNLPVSLASGVQSPIGTTGGGQ 460 Query: 449 QSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNXXXXXXXXXXXXMRSVN 508 Q+ PSLS+ + IDPSS++RAYAALGL +R++N Sbjct: 461 QTAPSLSSPNPIDPSSMQRAYAALGLPYGNPAQGTGQQPAQTQ--------VHQQIRNMN 512 Query: 509 NMSASPMGVN-GGVGV-QTPNLLSDSMLHSTINSQNPMMS---GNAGVASLGPLPTAAQP 563 + + M + GG+ V Q NL+SD+ L + + + N ++S G + V + G +PTAA P Sbjct: 513 ALGGNQMNLTAGGMTVEQQTNLISDTALPTALANSNSLLSDGNGQSTVGNHGTMPTAAPP 572 Query: 564 SSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYES 623 SSTG+RK WHE +TQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYES Sbjct: 573 SSTGVRKAWHEHVTQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYES 632 Query: 624 ANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPN-----APGMGPVPM-NTGSNMG 677 AN+R EYYH LAEKIYKIQKELEEKRR+RLQKQ ++ + APG P + T +G Sbjct: 633 ANSRDEYYHFLAEKIYKIQKELEEKRRSRLQKQGIMSSQAPLQAPGAQPTALTQTSPALG 692 Query: 678 QQPTGMTTNGP 688 Q TNGP Sbjct: 693 QTQPVRPTNGP 703
>gi|19173764|ref|NP_596894.1| E1A binding protein p300 [Rattus norvegicus] gi|15076626|dbj|BAB62425.1| E1A-binding protein [Rattus norvegicus] Length = 353 Score = 414 bits (1065), Expect = e-114 Identities = 272/353 (77%), Positives = 276/353 (78%) Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60 MAENVVEPGPP DGTDFGSLFDLEHDLPDELINSTELGLTNGGD Sbjct: 1 MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60 Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQAMASQACQNSPGLSLINS 120 SQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQ MASQA QNSPGLSLINS Sbjct: 61 ISQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQNSPGLSLINS 120 Query: 121 MVKSPMACTGLTSPNMGIGSSGPNQGPTQSPAGMMNSPVNQXXXXXXXXXXXXXXXXXLA 180 MVKSPMA TGLTSPNMG+GSSGPNQGPTQS AGMMNSPVNQ LA Sbjct: 121 MVKSPMAQTGLTSPNMGMGSSGPNQGPTQSTAGMMNSPVNQPAMGMNTGMNAGMNPGMLA 180 Query: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEXXXXXXXXXXXXXXXXXX 240 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTE Sbjct: 181 AGNGQGIMPNQVMNGSIGAGRGRPNMQYPNAGMGNAGSLLTEPLQQGSPQMGGQPGLRGP 240 Query: 241 XXLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXX 300 KMGMM+NP+PYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAV Sbjct: 241 QSHKMGMMSNPTPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVTGGGM 300 Query: 301 XXXXXXXXXSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQ 353 SVQQPGLV PVA GMGSGAHTADPEKR +IQQQLVLLLHAHKCQ Sbjct: 301 PNMGQQPTPSVQQPGLVNPVAPGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQ 353
>gi|2996629|gb|AAC08447.1| CBP [Homo sapiens] Length = 555 Score = 390 bits (1001), Expect = e-107 Identities = 255/451 (56%), Positives = 303/451 (67%), Gaps = 17/451 (3%) Query: 245 MGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXX 304 MG+ N SP+G P++Q GQ +GA+G+ Q+ +K + N+L F D K Sbjct: 1 MGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMS 60 Query: 305 XXXXXSVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQ 364 G+V A G TADPEKR +IQQQLVLLLHAHKCQRREQANGEVR Sbjct: 61 QMQ----TSVGIVPTQAIATGP---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRA 113 Query: 365 CNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDK 424 C+LPHCRTMKNVLNHMTHCQ+GK+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DK Sbjct: 114 CSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDK 173 Query: 425 RNQCSILTGAPVGLGNP-SSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXX 483 RNQ +IL G+ N S+G GQQ+ SLS + IDPSS++RAYAALGL Sbjct: 174 RNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQ 233 Query: 484 XXXXXAKNXXXXXXXXXXXXMRSVNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINS 540 MR++N + +PM + G Q PNL+S+S L +++ + Sbjct: 234 LQPQVPGQ--QPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGA 291 Query: 541 QNPMM---SGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPD 597 NP+M S + + +L +PTAA PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPD Sbjct: 292 TNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPD 351 Query: 598 PAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQN 657 PAALKDRRMENLVAYA+KVEGDMYESAN+R EYYHLLAEKIYKIQKELEEKRR+RL KQ Sbjct: 352 PAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQG 411 Query: 658 MLPNAPGMGPVPMNTGSNMGQQPTGMTTNGP 688 +L N P + P P + Q NGP Sbjct: 412 ILGNQPAL-PAPGAQPPVIPQAQPVRPPNGP 441
>gi|21307831|gb|AAL54859.1| CREB-binding protein [Aplysia californica] Length = 2245 Score = 249 bits (637), Expect = 9e-65 Identities = 244/653 (37%), Positives = 306/653 (46%), Gaps = 103/653 (15%) Query: 32 DFGSL-FD-LEHDLPDELINSTELGLTNGGDSSQLQTSLGIVQDAASKHKQLSELLRSGS 89 +FG+L FD + ++LPD+L GL G S QT G QD S LS+LL S S Sbjct: 31 NFGNLNFDGIVNELPDDLD-----GLQ--GTSGDGQTPQG-SQD-TSMGGSLSQLL-SRS 80 Query: 90 SPNLNMGVGGPGQAMASQACQNSP--GLSLINSMVKSPMACTGLTSPNMGIGSSGPNQGP 147 +PN + P + SP G + M K+PM+ + ++ N+ Sbjct: 81 TPNSQTSLPLPVNSAGGIQTSRSPGMGAMMNMGMGKNPMS--------NNLAATLANKAA 132 Query: 148 TQSPAGMMNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSIGAGRGRPNMQ 207 T S M ++ V+ G M N M GS+G+ N Q Sbjct: 133 TSSHMNMNDALVSSASFTISGTNAGPMGGVTNTMGMNP-TMGNPQMIGSVGS--LNMNQQ 189 Query: 208 YPNAGMGNAGSLLTEXXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQNSGQQIG 267 PN M S + GMM +P G P Q G Sbjct: 190 MPNQMMNGPTSFPGNMGQMRAMQGNNVNPSTSMQVPQTGMMQSP---GMPQMQGHQGMPG 246 Query: 268 ASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPVAAGMGSG 327 + + P N+ P P +G Sbjct: 247 HPNMNMPQNP----PQNIRPG-----------------------------QPTGSGTSGP 273 Query: 328 AHTA-DPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSG 386 A +P+K +IQQQLVLLLHAHKCQRREQ N E ++C LP+CRTMKNVLNHMT C G Sbjct: 274 RQAAGEPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKG 332 Query: 387 KSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGNPSSLGV 446 KSC+VAHCASSRQII+HWKNC R DCPVC LK A DKRN + G Sbjct: 333 KSCEVAHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRN----------------TQGQ 375 Query: 447 GQQSTPSLSTVSQIDPSSIERAYAALGLXXXXXXXXXXXXXXAKNXXXXXXXXXXXXMRS 506 T +++ + DP++++RA+ +LGL A N Sbjct: 376 SVNQTSTMTAPNAADPATMKRAFESLGL-------QYNQNTPAHNAAQHGHPQMNAMQND 428 Query: 507 VNNMSASPMGVNGGVGVQTPNLLSDSM----------LHSTINSQN--PMMSGNAGVASL 554 ++ + M G V P+ S M L TI Q+ + S A A++ Sbjct: 429 AGQINKTNMPNQQGPKV-VPDQSSSPMSMLPVPPTGQLPQTIQPQSGTQLASATAQAAAM 487 Query: 555 GPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYAR 614 G P + RK WH +TQDLRNHLVHKLVQAIFPTPD A L+D RM+NLVAYAR Sbjct: 488 GNAPDIVKSIPVSSRKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYAR 547 Query: 615 KVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNA--PGM 665 KVEGDMYESANNR +YYHLLAEKIYKIQKELEEKR R++ QN PNA PGM Sbjct: 548 KVEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQNA-PNAQVPGM 599
>gi|20664269|pdb|1L3E|B Chain B, Nmr Structures Of The Hif-1alpha CtadP300 CH1 COMPLEX gi|33357860|pdb|1P4Q|B Chain B, Solution Structure Of The Cited2 Transactivation Domain In Complex With The P300 Ch1 Domain Length = 101 Score = 194 bits (494), Expect = 3e-48 Identities = 99/101 (98%), Positives = 100/101 (99%) Query: 324 MGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHC 383 MGSGAHTADPEKR +IQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHC Sbjct: 1 MGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHC 60 Query: 384 QSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDK 424 QSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDK Sbjct: 61 QSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDK 101
>gi|20664319|pdb|1L8C|A Chain A, Structural Basis For Hif-1alphaCBP RECOGNITION IN THE Cellular Hypoxic Response Length = 95 Score = 179 bits (453), Expect = 2e-43 Identities = 88/95 (92%), Positives = 92/95 (96%) Query: 331 ADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQ 390 ADPEKR +IQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+GK+CQ Sbjct: 1 ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQ 60 Query: 391 VAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKR 425 VAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKR Sbjct: 61 VAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKR 95
>gi|4139873|pdb|1KDX|A Chain A, Kix Domain Of Mouse Cbp (Creb Binding Protein) In Complex With Phosphorylated Kinase Inducible Domain (Pkid) Of Rat Creb (Cyclic Amp Response Element Binding Protein), Nmr 17 Structures Length = 81 Score = 164 bits (415), Expect = 5e-39 Identities = 72/80 (90%), Positives = 77/80 (96%) Query: 568 IRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNR 627 +RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGDMYESAN+R Sbjct: 2 VRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSR 61 Query: 628 AEYYHLLAEKIYKIQKELEE 647 EYYHLLAEKIYKIQKELEE Sbjct: 62 DEYYHLLAEKIYKIQKELEE 81
>gi|17553334|ref|NP_499197.1| CREB-binding protein like family member (22.2 kD) (3L5) [Caenorhabditis elegans] gi|542476|pir||S42836 F40F12.7 protein - Caenorhabditis elegans gi|3877001|emb|CAA82938.1| Hypothetical protein F40F12.7 [Caenorhabditis elegans] Length = 199 Score = 130 bits (328), Expect = 7e-29 Identities = 63/108 (58%), Positives = 72/108 (66%), Gaps = 9/108 (8%) Query: 332 DPEKRNVIQQQLVLLLHAHKCQRREQANGEV---------RQCNLPHCRTMKNVLNHMTH 382 DP KR +IQQQ VLLLHAHKC +RE+ N E C LPHC TMK VL HMT+ Sbjct: 7 DPVKRKLIQQQFVLLLHAHKCSQREKENNEFAARNQLLPHAACTLPHCSTMKEVLIHMTN 66 Query: 383 CQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSI 430 C G+ C AHCASSRQII+HWK+C+R DCPVC PLK D Q S+ Sbjct: 67 CNVGRLCHFAHCASSRQIIAHWKDCSREDCPVCKPLKGIQDTPLQFSL 114
>gi|17552708|ref|NP_499161.1| CBP/p300 homolog (cbp-1) [Caenorhabditis elegans] gi|14530537|emb|CAA82353.2| C. elegans CBP-1 protein (corresponding sequence R10E11.1a) [Caenorhabditis elegans] Length = 2045 Score = 124 bits (310), Expect = 7e-27 Identities = 60/101 (59%), Positives = 78/101 (77%) Query: 555 GPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYAR 614 G +P P K+WH +T+DLRNHLV KLV+AIFP P+ A+ D R+++L+AYAR Sbjct: 570 GEIPNLPPPDMPDCTKEWHHQVTKDLRNHLVGKLVKAIFPEPNQEAMNDNRLKDLIAYAR 629 Query: 615 KVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQK 655 KVE +M+ESAN+R EYYHLLAEKIYKIQKEL+EK+ +RL + Sbjct: 630 KVEKEMFESANDREEYYHLLAEKIYKIQKELQEKKNSRLNQ 670
Score = 109 bits (273), Expect = 2e-22 Identities = 69/130 (53%), Positives = 79/130 (60%), Gaps = 9/130 (6%) Query: 310 SVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEV------- 362 + Q+ G G A DPEKR +IQQQLVLLLHAHKC +RE+ N + Sbjct: 377 AAQRNGAGRATTPGSSMLATHQDPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPP 436 Query: 363 --RQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN 420 C LPHC TMK VL HMT C G+ C AHCASSRQII+HWKNC+R DCPVC PLK Sbjct: 437 PHAACTLPHCSTMKEVLTHMTSCNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCKPLKR 496 Query: 421 AGDKRNQCSI 430 D Q S+ Sbjct: 497 IQDTPLQFSL 506
>gi|31204369|ref|XP_311133.1| ENSANGP00000004748 [Anopheles gambiae] gi|30178093|gb|EAA06516.2| ENSANGP00000004748 [Anopheles gambiae str. PEST] Length = 2572 Score = 121 bits (304), Expect = 4e-26 Identities = 77/149 (51%), Positives = 92/149 (61%), Gaps = 12/149 (8%) Query: 504 MRSVNNMSASPMGVNGGVGVQTPNLLSDSMLHSTINSQNPMMSGNAGVASLGPLPTAAQP 563 M +N + S M G G PN + S + S+ +P Sbjct: 689 MPLMNATNTSTM---SGGGGGGPN--TSSFAAGSGAGGGGAGGTGGTNPSMVAVPVQGT- 742 Query: 564 SSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYES 623 K WH +T DLRNHLVHKLVQAIFP+PDP+A+ D+RM NLVAYA+KVEGDMYE Sbjct: 743 ------KDWHHSVTPDLRNHLVHKLVQAIFPSPDPSAMFDKRMYNLVAYAKKVEGDMYEM 796 Query: 624 ANNRAEYYHLLAEKIYKIQKELEEKRRTR 652 AN+R+EYYHLLAEKIYKIQKELEEKR+ R Sbjct: 797 ANSRSEYYHLLAEKIYKIQKELEEKRQKR 825
Score = 115 bits (288), Expect = 2e-24 Identities = 66/101 (65%), Positives = 73/101 (72%) Query: 325 GSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQ 384 G ADPEKR +IQQQLVLLLHAHKCQRRE N C+L HCRTMK VL HM C Sbjct: 332 GGNPLLADPEKRKLIQQQLVLLLHAHKCQRREAENPSGNICSLAHCRTMKEVLTHMQSCL 391 Query: 385 SGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKR 425 GK+C HC+SSRQII+HWKNC R DCPVCLPL+ DK+ Sbjct: 392 LGKNCPKTHCSSSRQIINHWKNCQRQDCPVCLPLQQHHDKQ 432
>gi|7511830|pir||T13828 CREB-binding protein homolog - fruit fly (Drosophila melanogaster) gi|1916930|gb|AAB53050.1| CREB-binding protein homolog [Drosophila melanogaster] Length = 3190 Score = 118 bits (295), Expect = 4e-25 Identities = 70/137 (51%), Positives = 84/137 (61%) Query: 516 GVNGGVGVQTPNLLSDSMLHSTINSQNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHED 575 G +GG ++L + + N+ NP + G K W E Sbjct: 887 GASGGQVAAGSSVLMPADTTGSGNAGNPNQNAGGVAGGAGGGNGGNTGPPGDNEKDWRES 946 Query: 576 ITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLA 635 +T DLRNHLVHKLVQAIFPT DP ++D+RM NLV+YA KVE DMYE A +R+EYYHLLA Sbjct: 947 VTADLRNHLVHKLVQAIFPTSDPTTMQDKRMHNLVSYAEKVEKDMYEMAKSRSEYYHLLA 1006 Query: 636 EKIYKIQKELEEKRRTR 652 EKIYKIQKELEEKR R Sbjct: 1007 EKIYKIQKELEEKRLKR 1023
Score = 80.9 bits (198), Expect = 7e-14 Identities = 45/99 (45%), Positives = 61/99 (61%) Query: 321 AAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHM 380 ++G G +++ IQQQL+LLLHAHKC RRE N CN+ +C+ MK+VL HM Sbjct: 497 SSGPGGANRDVPDDRKRQIQQQLMLLLHAHKCNRRENLNPNREVCNVNYCKAMKSVLAHM 556 Query: 381 THCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 419 C+ K C + HCASSRQI+ H+K C C +C P + Sbjct: 557 GTCKQSKDCTMQHCASSRQILLHYKTCQNSGCVICYPFR 595
Score = 38.9 bits (89), Expect = 0.35 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 13/88 (14%) Query: 331 ADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQ 390 A+P++ Q + AH CQ R+ C LP C+ MK V+ H +C+ + Sbjct: 2389 ANPQEARKQSIQRCIQSLAHACQCRDA------NCRLPSCQKMKLVVQHTKNCKRKPN-- 2440 Query: 391 VAHCASSRQIIS----HWKNCTRHDCPV 414 C +Q+I+ H KNC CPV Sbjct: 2441 -GGCPICKQLIALCCYHAKNCEEQKCPV 2467
>gi|24640865|ref|NP_524642.2| nejire CG15319-PB [Drosophila melanogaster] gi|22833041|gb|AAF46516.2| CG15319-PB [Drosophila melanogaster] Length = 3276 Score = 117 bits (293), Expect = 7e-25 Identities = 70/137 (51%), Positives = 84/137 (61%) Query: 516 GVNGGVGVQTPNLLSDSMLHSTINSQNPMMSGNAGVASLGPLPTAAQPSSTGIRKQWHED 575 G +GG ++L + + N+ NP + G K W E Sbjct: 887 GASGGQVAAGSSVLMPADTTGSGNAGNPNQNAGGVAGGAGGGNGGNTGPPGDNEKDWRES 946 Query: 576 ITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLA 635 +T DLRNHLVHKLVQAIFPT DP ++D+RM NLV+YA KVE DMYE A +R+EYYHLLA Sbjct: 947 VTADLRNHLVHKLVQAIFPTSDPTTMQDKRMHNLVSYAEKVEKDMYEMAKSRSEYYHLLA 1006 Query: 636 EKIYKIQKELEEKRRTR 652 EKIYKIQKELEEKR R Sbjct: 1007 EKIYKIQKELEEKRLKR 1023
Score = 80.5 bits (197), Expect = 1e-13 Identities = 45/99 (45%), Positives = 61/99 (61%) Query: 321 AAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHM 380 ++G G +++ IQQQL+LLLHAHKC RRE N CN+ +C+ MK+VL HM Sbjct: 497 SSGPGGANRDVPDDRKRQIQQQLMLLLHAHKCNRRENLNPNREVCNVNYCKAMKSVLAHM 556 Query: 381 THCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 419 C+ K C + HCASSRQI+ H+K C C +C P + Sbjct: 557 GTCKQSKDCTMQHCASSRQILLHYKTCQNSGCVICYPFR 595
Score = 38.5 bits (88), Expect = 0.44 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 13/88 (14%) Query: 331 ADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQ 390 A+P++ Q + AH CQ R+ C LP C+ MK V+ H +C+ + Sbjct: 2389 ANPQEARKQSIQRCIQSLAHACQCRDA------NCRLPSCQKMKLVVQHTKNCKRKPN-- 2440 Query: 391 VAHCASSRQIIS----HWKNCTRHDCPV 414 C +Q+I+ H KNC CPV Sbjct: 2441 -GGCPICKQLIALCCYHAKNCEEQKCPV 2467
>gi|7494646|pir||T37269 hypothetical protein - Caenorhabditis elegans (fragment) gi|2665395|dbj|BAA23766.1| unnamed protein product [Caenorhabditis elegans] Length = 118 Score = 117 bits (293), Expect = 8e-25 Identities = 65/108 (60%), Positives = 73/108 (67%), Gaps = 9/108 (8%) Query: 332 DPEKRNVIQQQLVLLLHAHKCQRREQANGEV---------RQCNLPHCRTMKNVLNHMTH 382 DPEKR +IQQQLVLLLHAHKC +RE+ N + C LPHC TMK VL HMT Sbjct: 3 DPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTS 62 Query: 383 CQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSI 430 C G+ C AHCASSRQII+HWKNC+R DCPVC PLK D Q S+ Sbjct: 63 CNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCKPLKRIQDTPLQFSL 110
>gi|482238|pir||S41033 hypothetical protein K03H1.10 - Caenorhabditis elegans (fragment) Length = 316 Score = 110 bits (276), Expect = 6e-23 Identities = 61/101 (60%), Positives = 70/101 (69%), Gaps = 9/101 (8%) Query: 332 DPEKRNVIQQQLVLLLHAHKCQRREQANGEV---------RQCNLPHCRTMKNVLNHMTH 382 DP K+ ++QQQLVLLLHAHKC R++ N E C LPHC TMK VL HMT+ Sbjct: 1 DPVKQKLVQQQLVLLLHAHKCSLRDKENNEFAARNQPLPHTTCRLPHCPTMKEVLIHMTN 60 Query: 383 CQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGD 423 C G+ C AHCASSRQII+HWKNC+R DCPVC PLK A D Sbjct: 61 CNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCTPLKRARD 101
Score = 105 bits (263), Expect = 2e-21 Identities = 55/112 (49%), Positives = 77/112 (68%), Gaps = 5/112 (4%) Query: 544 MMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKD 603 M +G ++ LP P T K+WH +T DLRNH+V KLV+AI P P+ + D Sbjct: 138 MSAGRITNGNISNLPPPNVPVRT---KEWHRQVTNDLRNHIVGKLVKAICPAPE--MMND 192 Query: 604 RRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQK 655 R+++L AYARKVE +++E+A +R YYHLLAEKIY+IQKEL+EK+ +RL + Sbjct: 193 IRLKDLNAYARKVEKEVFETAIDRKNYYHLLAEKIYEIQKELQEKKNSRLNQ 244
>gi|17554044|ref|NP_499201.1| CREB-binding protein like family member (36.7 kD) (3L15) [Caenorhabditis elegans] gi|25395947|pir||D88569 protein K03H1.10 [imported] - Caenorhabditis elegans gi|3877003|emb|CAA82940.1| Hypothetical protein K03H1.10 [Caenorhabditis elegans] gi|3878179|emb|CAA82665.1| Hypothetical protein K03H1.10 [Caenorhabditis elegans] Length = 322 Score = 110 bits (276), Expect = 7e-23 Identities = 61/101 (60%), Positives = 70/101 (69%), Gaps = 9/101 (8%) Query: 332 DPEKRNVIQQQLVLLLHAHKCQRREQANGEV---------RQCNLPHCRTMKNVLNHMTH 382 DP K+ ++QQQLVLLLHAHKC R++ N E C LPHC TMK VL HMT+ Sbjct: 7 DPVKQKLVQQQLVLLLHAHKCSLRDKENNEFAARNQPLPHTTCRLPHCPTMKEVLIHMTN 66 Query: 383 CQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGD 423 C G+ C AHCASSRQII+HWKNC+R DCPVC PLK A D Sbjct: 67 CNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCTPLKRARD 107
Score = 105 bits (262), Expect = 3e-21 Identities = 55/112 (49%), Positives = 77/112 (68%), Gaps = 5/112 (4%) Query: 544 MMSGNAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKD 603 M +G ++ LP P T K+WH +T DLRNH+V KLV+AI P P+ + D Sbjct: 144 MSAGRITNGNISNLPPPNVPVRT---KEWHRQVTNDLRNHIVGKLVKAICPAPE--MMND 198 Query: 604 RRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQK 655 R+++L AYARKVE +++E+A +R YYHLLAEKIY+IQKEL+EK+ +RL + Sbjct: 199 IRLKDLNAYARKVEKEVFETAIDRKNYYHLLAEKIYEIQKELQEKKNSRLNQ 250
>gi|2133462|pir||S60123 hypothetical protein R10E11.1 - Caenorhabditis elegans Length = 2027 Score = 105 bits (261), Expect = 3e-21 Identities = 71/141 (50%), Positives = 81/141 (57%), Gaps = 20/141 (14%) Query: 310 SVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEV------- 362 + Q+ G G A DPEKR +IQQQLVLLLHAHKC +RE+ N + Sbjct: 377 AAQRNGAGRATTPGSSMLATHQDPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPP 436 Query: 363 --RQCNLPHCRTMKNVLNHMTHC-----------QSGKSCQVAHCASSRQIISHWKNCTR 409 C LPHC TMK VL HMT C Q+ K C VAHCASSRQII+HWKNC+R Sbjct: 437 PHAACTLPHCSTMKEVLTHMTSCNVGRLCHSDTTQTTKKCSVAHCASSRQIIAHWKNCSR 496 Query: 410 HDCPVCLPLKNAGDKRNQCSI 430 DCPVC PLK D Q S+ Sbjct: 497 EDCPVCKPLKRIQDTPLQFSL 517
>gi|17552710|ref|NP_499160.1| CBP/p300 homolog (cbp-1) [Caenorhabditis elegans] gi|20455476|sp|P34545|CBP1_CAEEL Protein cbp-1 gi|25299632|pir||G88564 protein R10E11.1 [imported] - Caenorhabditis elegans gi|17645979|emb|CAD18875.1| C. elegans CBP-1 protein (corresponding sequence R10E11.1b) [Caenorhabditis elegans] Length = 2056 Score = 104 bits (260), Expect = 4e-21 Identities = 71/141 (50%), Positives = 81/141 (57%), Gaps = 20/141 (14%) Query: 310 SVQQPGLVTPVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEV------- 362 + Q+ G G A DPEKR +IQQQLVLLLHAHKC +RE+ N + Sbjct: 377 AAQRNGAGRATTPGSSMLATHQDPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPP 436 Query: 363 --RQCNLPHCRTMKNVLNHMTHC-----------QSGKSCQVAHCASSRQIISHWKNCTR 409 C LPHC TMK VL HMT C Q+ K C VAHCASSRQII+HWKNC+R Sbjct: 437 PHAACTLPHCSTMKEVLTHMTSCNVGRLCHSDTTQTTKKCSVAHCASSRQIIAHWKNCSR 496 Query: 410 HDCPVCLPLKNAGDKRNQCSI 430 DCPVC PLK D Q S+ Sbjct: 497 EDCPVCKPLKRIQDTPLQFSL 517
>gi|17552400|ref|NP_497145.1| CREB-binding protein like family member (3A735) [Caenorhabditis elegans] gi|7496696|pir||T33580 hypothetical protein C29F9.5 - Caenorhabditis elegans gi|3790687|gb|AAC68747.1| Hypothetical protein C29F9.5 [Caenorhabditis elegans] Length = 226 Score = 92.4 bits (228), Expect = 2e-17 Identities = 42/90 (46%), Positives = 52/90 (57%), Gaps = 9/90 (10%) Query: 338 VIQQQLVLLLHAHKCQRREQANGEVRQ---------CNLPHCRTMKNVLNHMTHCQSGKS 388 +I +QL LLLHAH+C RR+ E + C + C MK VL HMT C+ G Sbjct: 4 LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63 Query: 389 CQVAHCASSRQIISHWKNCTRHDCPVCLPL 418 C HCASSR I+SHWK C +CPVC P+ Sbjct: 64 CNSVHCASSRTILSHWKKCFNEECPVCKPI 93
Score = 54.3 bits (129), Expect = 7e-06 Identities = 23/93 (24%), Positives = 47/93 (50%) Query: 559 TAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG 618 T A+P + WH ++ + R+ L+ K+ + I P L + +M+ Y+R E Sbjct: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164 Query: 619 DMYESANNRAEYYHLLAEKIYKIQKELEEKRRT 651 ++++A YYH+ EK+ + Q+ +++T Sbjct: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
>gi|19173734|ref|NP_596872.1| CREB binding protein; Creb binding protein (CBP) [Rattus norvegicus] gi|15076624|dbj|BAB62424.1| CREB-binding protein [Rattus norvegicus] Length = 351 Score = 89.4 bits (220), Expect = 2e-16 Identities = 115/375 (30%), Positives = 155/375 (41%), Gaps = 64/375 (17%) Query: 1 MAENVVEPGPPXXXXXXXXXXXXXXXXXDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60 MAEN+++ GPP D TDFGSLFDLE+DLPDELI + EL L N G+ Sbjct: 1 MAENLLD-GPP--NPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGELSLLNSGN 57 Query: 61 SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQA--------MASQACQNS 112 +V DAASKHKQLSELLR GS ++ G+G + +Q NS Sbjct: 58 ---------LVPDAASKHKQLSELLRGGSGSSITPGIGNVSASSPVQQGLGGQAQGQPNS 108 Query: 113 PGLSLINSMVKSPMACTGLTSPNM---GIGSSGPNQGPTQS------------------- 150 ++ + +M KSP+ ++P++ +SGP +Q+ Sbjct: 109 TSMASLGAMGKSPLNPGDSSTPSLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATS 168 Query: 151 ---PAGMMNSPVNQXXXXXXXXXXXXXXXXXLAAGNGQGIMPNQVMNGSI--GAGRGRPN 205 P MN+ NQ G QVMNGS+ Sbjct: 169 QTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQA------QVMNGSLGAAGRGRGAG 222 Query: 206 MQYPNAGM-GNAGSLLTE---XXXXXXXXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQN 261 M YP M G S+L E KMGM N SP+G P++Q Sbjct: 223 MPYPAPAMQGATSSVLAETLTQVSPQMAGHAGLNTAQAGGMTKMGMTGNTSPFGQPFSQT 282 Query: 262 SGQQIGASGLGLQIQTKTVLPNNLSPFAMDKKAVXXXXXXXXXXXXXXSVQQPGLVTPVA 321 GQ +GA+G+ Q+ +K + N+L F D K S Q + A Sbjct: 283 GGQPMGATGVNPQLASKQSMVNSLPAFPTDIKNT------SVTTVPNMSQLQTSVGIVPA 336 Query: 322 AGMGSGAHTADPEKR 336 G+ +G TADPEKR Sbjct: 337 QGIATGP-TADPEKR 350
>gi|9368432|emb|CAB98139.1| MOZ/CBP protein [Homo sapiens] Length = 376 Score = 89.0 bits (219), Expect = 2e-16 Identities = 97/305 (31%), Positives = 135/305 (44%), Gaps = 55/305 (18%) Query: 29 DGTDFGSLFDLEHDLPDELI-NSTELGLTNGGDSSQLQTSLGIVQDAASKHKQLSELLRS 87 D DFGSLFDLE+DLPDELI N ELGL N G+ +V DAASKHKQLSELLR Sbjct: 60 DADDFGSLFDLENDLPDELIPNGGELGLLNSGN---------LVPDAASKHKQLSELLRG 110 Query: 88 GSSPNLNMGVGGPGQA--------MASQACQNSPGLSLINSMVKSPMACTGLTSPNM--- 136 GS ++N G+G + +Q NS ++ +++M KSP++ ++P++ Sbjct: 111 GSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQ 170 Query: 137 GIGSSGPNQGPTQS----------------------PAGMMNSPVNQXXXXXXXXXXXXX 174 +SGP +Q+ P MN+ NQ Sbjct: 171 AASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNSGHS 230 Query: 175 XXXXLAAGNGQGIMPNQVMNGSI--GAGRGRPNMQYPNAGM-GNAGSLLTE---XXXXXX 228 + G QVMNGS+ M YP M G + S+L E Sbjct: 231 LINQASQGQA------QVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQM 284 Query: 229 XXXXXXXXXXXXXXLKMGMMNNPSPYGSPYTQNSGQQIGASGLGLQIQTKTVLPNNLSPF 288 KMG+ N SP+G P++Q GQ +GA+G+ Q+ +K + N+L F Sbjct: 285 TGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTF 344 Query: 289 AMDKK 293 D K Sbjct: 345 PTDIK 349
>gi|17551090|ref|NP_510006.1| CREB-binding protein like family member (XM605) [Caenorhabditis elegans] gi|7497672|pir||T20071 hypothetical protein C49F5.5 - Caenorhabditis elegans gi|3875065|emb|CAB03976.1| Hypothetical protein C49F5.5 [Caenorhabditis elegans] Length = 151 Score = 86.7 bits (213), Expect = 1e-15 Identities = 35/97 (36%), Positives = 56/97 (57%), Gaps = 9/97 (9%) Query: 332 DPEKRNVIQQQLVLLLHAHKCQRREQANGEVR---------QCNLPHCRTMKNVLNHMTH 382 DP VI++QL+LLLHA+ C +R++ N + +C+LP C K L+H+ Sbjct: 47 DPHILKVIKEQLILLLHANVCTKRDRENYQAAINGQPARHPRCDLPSCGLFKYTLSHLNM 106 Query: 383 CQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 419 C +G C + +C +S+Q+I HW+ C C +C PL+ Sbjct: 107 CTNGSHCLIDYCNTSKQLIKHWRECQNRACAICAPLR 143
>gi|17552402|ref|NP_497144.1| CREB-binding protein like family member (3A733) [Caenorhabditis elegans] gi|7496697|pir||T33579 hypothetical protein C29F9.6 - Caenorhabditis elegans gi|3790688|gb|AAC68748.1| Hypothetical protein C29F9.6 [Caenorhabditis elegans] Length = 228 Score = 70.1 bits (170), Expect = 1e-10 Identities = 26/52 (50%), Positives = 32/52 (61%) Query: 364 QCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVC 415 QC +P C TMK V+ HM C +G C HC SSR +I HW CT +CP+C Sbjct: 37 QCPVPQCSTMKEVIGHMMTCWNGFQCPSEHCTSSRMVIHHWTRCTNAECPIC 88
Score = 38.5 bits (88), Expect = 0.44 Identities = 26/112 (23%), Positives = 49/112 (43%), Gaps = 10/112 (8%) Query: 548 NAGVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRME 607 N S P+ +P G + WH ++ + R ++ ++ + I P +R E Sbjct: 96 NMNALSTIPIVKDPEPRPPGTSQPWHSEVPKTDREAVIERISKHIMLHP-------QRFE 148 Query: 608 ---NLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQ 656 + AR E ++E+A +R EYY ++ E+ + Q + E QK+ Sbjct: 149 PIWKIKEDARAAELQIFEAAGSRDEYYRMVEERAPREQDKAPEGPGQEAQKE 200
>gi|12718195|emb|CAC28863.1| MORF/CBP protein [Homo sapiens] Length = 141 Score = 67.4 bits (163), Expect = 9e-10 Identities = 40/64 (62%), Positives = 46/64 (71%), Gaps = 10/64 (15%) Query: 32 DFGSLFDLEHDLPDELI-NSTELGLTNGGDSSQLQTSLGIVQDAASKHKQLSELLRSGSS 90 +FGSLFDLE+DLPDELI N ELGL N G+ +V DAASKHKQLSELLR GS Sbjct: 87 NFGSLFDLENDLPDELIPNGGELGLLNSGN---------LVPDAASKHKQLSELLRGGSG 137 Query: 91 PNLN 94 ++N Sbjct: 138 SSIN 141
>gi|21105780|gb|AAM34788.1|AF512558_2 HAC5 [Arabidopsis thaliana] Length = 1012 Score = 62.4 bits (150), Expect = 3e-08 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 7/85 (8%) Query: 343 LVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIIS 402 L+ LLH KC E C +C T K +L H+ C++ +C +C +RQ+I Sbjct: 94 LLFLLHVRKCNAAED------NCESKYCFTAKTLLKHINCCKA-PACAYQYCHQTRQLIH 146 Query: 403 HWKNCTRHDCPVCLPLKNAGDKRNQ 427 H+K+C CPVC+ +KN +K+ + Sbjct: 147 HYKHCGDEACPVCVFVKNFKEKQKE 171
>gi|15230656|ref|NP_187904.1| CREB-binding protein -related [Arabidopsis thaliana] gi|15795129|dbj|BAB02507.1| CREB-binding protein-like [Arabidopsis thaliana] Length = 1670 Score = 59.7 bits (143), Expect = 2e-07 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 7/85 (8%) Query: 343 LVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIIS 402 L+ LLH KC E C +C T K +L H+ C++ +C +C +RQ+I Sbjct: 622 LLFLLHVRKCNAAED------NCESKYCFTAKTLLKHINCCKA-PACAYQYCHQTRQLIH 674 Query: 403 HWKNCTRHDCPVCLPLKNAGDKRNQ 427 H+K+C CPVC+ +KN +K+ + Sbjct: 675 HYKHCGDEACPVCVFVKNFKEKQKE 699
>gi|21466092|pdb|1LIQ|A Chain A, Non-Native Solution Structure Of A Fragment Of The Ch1 Domain Of Cbp Length = 27 Score = 58.5 bits (140), Expect = 4e-07 Identities = 24/27 (88%), Positives = 26/27 (96%) Query: 361 EVRQCNLPHCRTMKNVLNHMTHCQSGK 387 EVR C+LPHCRTMKNVLNHMTHCQ+GK Sbjct: 1 EVRACSLPHCRTMKNVLNHMTHCQAGK 27
>gi|17508323|ref|NP_493339.1| CREB-binding protein like family member (80.3 kD) (1N890) [Caenorhabditis elegans] gi|7505888|pir||T23651 hypothetical protein M01E5.6 - Caenorhabditis elegans gi|3878635|emb|CAB07643.1| Hypothetical protein M01E5.6 [Caenorhabditis elegans] gi|3879438|emb|CAB03290.1| Hypothetical protein M01E5.6 [Caenorhabditis elegans] Length = 702 Score = 55.1 bits (131), Expect = 4e-06 Identities = 30/96 (31%), Positives = 54/96 (56%), Gaps = 4/96 (4%) Query: 566 TGIRKQWHEDITQDLRNHLVHKLVQAIFP-TPDPAALKDRRMENLVAYARKVEGDMYESA 624 T K+W I +D+RNH+V KL++A +P + + + L+A ARK E ++ E++ Sbjct: 596 TNTSKEW---IVEDIRNHMVGKLLKAFWPRIQNVEEMNGELFKKLIANARKCETEILEAS 652 Query: 625 NNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP 660 N+R EYY L+ + +I K+ +K + + + P Sbjct: 653 NDRDEYYRLMQLTVDQILKKTLKKDQRATEHNHQQP 688
>gi|7487910|pir||T01055 hypothetical protein YUP8H12R.38 - Arabidopsis thaliana gi|3152587|gb|AAC17068.1| Similar to CREB-binding protein homolog gb|U88570 from D. melanogaster and contains similarity to callus-associated protein gb|U01961 from Nicotiana tabacum. EST gb|W43427 comes from this gene. [Arabidopsis thaliana] Length = 1516 Score = 54.3 bits (129), Expect = 8e-06 Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 8/101 (7%) Query: 319 PVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLN 378 P A +G DP +N Q+ L+ L HA C+ E +C +C T++ + Sbjct: 498 PTATTCRNGNGNRDPRFKNQ-QKWLLFLRHARHCKAPEG------KCPDRNCVTVQKLWK 550 Query: 379 HMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 419 HM C + C C ++ +I+H ++C +CPVC+P+K Sbjct: 551 HMDSC-AAPQCSYPRCLPTKTLINHHRSCKEPNCPVCIPVK 590
>gi|18412221|ref|NP_565197.1| p300/CBP acetyltransferase-related protein 2 [Arabidopsis thaliana] gi|12597461|gb|AAG60059.1| p300/CBP acetyltransferase-related protein 2 [Arabidopsis thaliana] Length = 1654 Score = 53.9 bits (128), Expect = 1e-05 Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 8/101 (7%) Query: 319 PVAAGMGSGAHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLN 378 P A +G DP +N Q+ L+ L HA C+ E +C +C T++ + Sbjct: 612 PTATTCRNGNGNRDPRFKNQ-QKWLLFLRHARHCKAPEG------KCPDRNCVTVQKLWK 664 Query: 379 HMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLK 419 HM C + C C ++ +I+H ++C +CPVC+P+K Sbjct: 665 HMDSC-AAPQCSYPRCLPTKTLINHHRSCKEPNCPVCIPVK 704
>gi|25518555|pir||E86302 hypothetical protein F17F16.8 [imported] - Arabidopsis thaliana gi|9954734|gb|AAG09087.1|AC026237_8 Unknown Protein [Arabidopsis thaliana] Length = 1498 Score = 52.8 bits (125), Expect = 2e-05 Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 8/95 (8%) Query: 332 DPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQV 391 DP+ +N Q+ L+ L HA C+ G +C +C T++ + +HM +C + C Sbjct: 430 DPKFKNQ-QRWLLFLRHARSCK---PPGG---RCQDQNCVTVQKLWSHMDNC-ADPQCLY 481 Query: 392 AHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRN 426 C ++ +I H+KNC CPVC+P+K + N Sbjct: 482 PRCRHTKALIGHYKNCKDPRCPVCVPVKTYQQQAN 516
>gi|17567279|ref|NP_509376.1| CREB-binding protein like (XI780) [Caenorhabditis elegans] gi|7499689|pir||T16139 hypothetical protein F22F1.3 - Caenorhabditis elegans gi|1118044|gb|AAA83283.1| Hypothetical protein F22F1.3 [Caenorhabditis elegans] Length = 295 Score = 52.0 bits (123), Expect = 4e-05 Identities = 23/72 (31%), Positives = 42/72 (58%) Query: 576 ITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLA 635 IT+ +R H++ KL +FP PD A D RM+ ++ R +E + + + +YY+L + Sbjct: 187 ITRRIRIHVIDKLGLMLFPAPDQNAYYDGRMDRIIRKLRNLEAEAFRECIDCDDYYNLAS 246 Query: 636 EKIYKIQKELEE 647 K YK+ K +++ Sbjct: 247 IKAYKLHKTMKK 258
Score = 48.9 bits (115), Expect = 3e-04 Identities = 24/73 (32%), Positives = 38/73 (52%) Query: 576 ITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLA 635 + + LR +++ K+V+ P P+ A D RM L YA +E +E + EYY LA Sbjct: 66 LERGLRQYMITKIVREAVPRPNSDAKNDARMIELKEYATFMEKKSFEKVQTKDEYYAELA 125 Query: 636 EKIYKIQKELEEK 648 I +QK L+ + Sbjct: 126 RIILSMQKHLQSR 138
>gi|15219327|ref|NP_173115.1| expressed protein [Arabidopsis thaliana] Length = 1706 Score = 52.0 bits (123), Expect = 4e-05 Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 8/95 (8%) Query: 332 DPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQV 391 DP+ +N Q+ L+ L HA C+ G +C +C T++ + +HM +C + C Sbjct: 638 DPKFKNQ-QRWLLFLRHARSCK---PPGG---RCQDQNCVTVQKLWSHMDNC-ADPQCLY 689 Query: 392 AHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRN 426 C ++ +I H+KNC CPVC+P+K + N Sbjct: 690 PRCRHTKALIGHYKNCKDPRCPVCVPVKTYQQQAN 724
>gi|7489105|pir||T02019 callus-associated protein - common tobacco (fragment) gi|432982|gb|AAA03633.1| callus associated protein Length = 670 Score = 47.0 bits (110), Expect = 0.001 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 9/89 (10%) Query: 333 PEKRNVIQQQ--LVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQ 390 P +R + Q+ L+ L+HA +C E +C +C + +L HM C C Sbjct: 468 PRERQYLNQKRWLLFLIHARRCSAPEG------KCPENNCIHAQKLLRHMERCIK-FDCP 520 Query: 391 VAHCASSRQIISHWKNCTRHDCPVCLPLK 419 C ++ +I+H K+C +CPVC+P+K Sbjct: 521 YPRCPETKVLINHHKHCKNENCPVCIPVK 549
>gi|11514507|pdb|1F81|A Chain A, Solution Structure Of The Taz2 Domain Of The Transcriptional Adaptor Protein Cbp Length = 88 Score = 42.7 bits (99), Expect = 0.024 Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 17/92 (18%) Query: 335 KRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHC 394 +R IQ+ + L+HA +C+ AN C+LP C+ MK V+ H C+ + C Sbjct: 7 RRLSIQRCIQSLVHACQCR---NAN-----CSLPSCQKMKRVVQHTKGCKRKTN---GGC 55 Query: 395 ASSRQIIS----HWKNCTRHDCPV--CLPLKN 420 +Q+I+ H K+C + CPV CL +K+ Sbjct: 56 PVCKQLIALCCYHAKHCQENKCPVPFCLNIKH 87
>gi|6056385|gb|AAF02849.1|AC009894_20 Unknown protein [Arabidopsis thaliana] Length = 1209 Score = 37.7 bits (86), Expect = 0.72 Identities = 17/88 (19%), Positives = 40/88 (45%), Gaps = 7/88 (7%) Query: 337 NVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCAS 396 N + + + + HA C+ ++ +C C + ++ H+ C+ +C+ +C Sbjct: 421 NTVLRWIPFMFHARHCKAKKD------KCASKFCFQARKIVKHIDCCKV-PNCKYRYCLG 473 Query: 397 SRQIISHWKNCTRHDCPVCLPLKNAGDK 424 +R + H+K C C C+ ++ +K Sbjct: 474 TRMWLDHFKQCKSISCRTCVAVREYMEK 501
>gi|14794966|gb|AAK73519.1| HAC4 [Arabidopsis thaliana] Length = 413 Score = 37.4 bits (85), Expect = 0.85 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 9/76 (11%) Query: 348 HAHKCQRRE--------QANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQ 399 H+HK R Q NG+ Q +K +L H C+S + CQ C S+ Sbjct: 278 HSHKLTSRSSSTDSTVVQQNGQASQSYQVKLEKLKKLLVHAATCRSTQ-CQYQGCRKSKM 336 Query: 400 IISHWKNCTRHDCPVC 415 + H +CT DCP+C Sbjct: 337 LFRHCIDCTTGDCPIC 352
>gi|21105785|gb|AAM34790.1|AF512560_2 HAC4 [Arabidopsis thaliana] Length = 385 Score = 37.4 bits (85), Expect = 0.96 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 9/76 (11%) Query: 348 HAHKCQRRE--------QANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQ 399 H+HK R Q NG+ Q +K +L H C+S + CQ C S+ Sbjct: 250 HSHKLTSRSSSTDSTVVQQNGQASQSYQVKLEKLKKLLVHAATCRSTQ-CQYQGCRKSKM 308 Query: 400 IISHWKNCTRHDCPVC 415 + H +CT DCP+C Sbjct: 309 LFRHCIDCTTGDCPIC 324