BLASTP 2.2.6 [Apr-09-2003]

RID: 1063376412-17047-1978105.BLASTQ3

Query= CBP_MOUSE gi|1345703|sp|P45481|CBP_MOUSE CREB-binding
protein
         (2441 letters)


Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF 
           1,522,899 sequences; 490,308,901 total letters

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|1345703|sp|P45481|CBP_MOUSE  CREB-binding protein >gi|481...  3467   0.0  
gi|737920|prf||1923401A  protein CBP                             3465   0.0  
gi|19547885|gb|AAL87531.1|  CREB-binding protein [Mus muscul...  3387   0.0  
gi|631119|pir||S39162  transcription coactivator CREB-bindin...  3359   0.0  
gi|4321116|gb|AAC51331.2|  CREB-binding protein [Homo sapiens]   3214   0.0  
gi|4758056|ref|NP_004371.1|  CREB binding protein [Homo sapi...  3213   0.0  
gi|27666550|ref|XP_235770.1|  similar to E1A-associated prot...  1126   0.0  
gi|31204369|ref|XP_311133.1|  ENSANGP00000004748 [Anopheles ...  1021   0.0  
gi|7511830|pir||T13828  CREB-binding protein homolog - fruit...  1004   0.0  
gi|24640865|ref|NP_524642.2|  nejire CG15319-PB [Drosophila ...   995   0.0  
gi|1888540|gb|AAC51340.1|  CREB-binding protein [Homo sapiens]    978   0.0  
gi|3168627|gb|AAC17736.1|  CBP [Homo sapiens]                     869   0.0  
gi|2996629|gb|AAC08447.1|  CBP [Homo sapiens]                     863   0.0  
gi|27881767|gb|AAH44677.1|  Similar to CREB binding protein ...   847   0.0  
gi|17552708|ref|NP_499161.1|  CBP/p300 homolog (cbp-1) [Caen...   701   0.0  
gi|17552710|ref|NP_499160.1|  CBP/p300 homolog (cbp-1) [Caen...   701   0.0  
gi|2133462|pir||S60123  hypothetical protein R10E11.1 - Caen...   700   0.0  
gi|31753089|gb|AAH53889.1|  Unknown (protein for IMAGE:61513...   541   e-152
gi|4557557|ref|NP_001420.1|  E1A binding protein p300; E1A-b...   530   e-148
gi|547239|gb|AAB31182.1|  p300=transcription coactivator {N-...   498   e-139
gi|28486616|ref|XP_283295.1|  similar to E1A-associated prot...   483   e-134
gi|19173734|ref|NP_596872.1|  CREB binding protein; Creb bin...   449   e-124
gi|27663074|ref|XP_235502.1|  similar to E1A-associated prot...   392   e-107
gi|9368432|emb|CAB98139.1|  MOZ/CBP protein [Homo sapiens]        366   2e-99
gi|28486618|ref|XP_128116.2|  similar to E1A-associated prot...   339   4e-91
gi|27667568|ref|XP_213219.1|  similar to CREB-binding protei...   284   1e-74
gi|21307831|gb|AAL54859.1|  CREB-binding protein [Aplysia ca...   266   3e-69
gi|23200188|pdb|1JSP|B  Chain B, Nmr Structure Of Cbp Bromod...   244   1e-62
gi|21105780|gb|AAM34788.1|AF512558_2  HAC5 [Arabidopsis thal...   239   4e-61
gi|15230656|ref|NP_187904.1|  CREB-binding protein -related ...   232   8e-59
gi|7487910|pir||T01055  hypothetical protein YUP8H12R.38 - A...   218   1e-54
gi|18412221|ref|NP_565197.1|  p300/CBP acetyltransferase-rel...   216   4e-54
gi|25518555|pir||E86302  hypothetical protein F17F16.8 [impo...   205   8e-51
gi|15219327|ref|NP_173115.1|  expressed protein [Arabidopsis...   204   2e-50
gi|18405622|ref|NP_564706.1|  CREB-binding protein -related ...   197   2e-48
gi|5042442|gb|AAD38279.1|AC007789_5  putative CREB-binding p...   192   1e-46
gi|13486836|dbj|BAB40067.1|  putative CREB-binding protein [...   191   1e-46
gi|18408717|ref|NP_564891.1|  hypothetical protein [Arabidop...   189   4e-46
gi|11514507|pdb|1F81|A  Chain A, Solution Structure Of The T...   187   3e-45
gi|20664319|pdb|1L8C|A  Chain A, Structural Basis For Hif-1a...   178   1e-42
gi|4139873|pdb|1KDX|A  Chain A, Kix Domain Of Mouse Cbp (Cre...   175   9e-42
gi|6056385|gb|AAF02849.1|AC009894_20  Unknown protein [Arabi...   171   2e-40
gi|1888538|gb|AAC51339.1|  CREB-binding protein [Homo sapiens]    171   2e-40
gi|20664269|pdb|1L3E|B  Chain B, Nmr Structures Of The Hif-1...   170   3e-40
gi|8778322|gb|AAF79331.1|AC002304_24  F14J16.27 [Arabidopsis...   159   5e-37
gi|17553334|ref|NP_499197.1|  CREB-binding protein like fami...   132   8e-29
gi|19173764|ref|NP_596894.1|  E1A binding protein p300 [Ratt...   125   8e-27
gi|14794966|gb|AAK73519.1|  HAC4 [Arabidopsis thaliana]           124   3e-26
gi|21105785|gb|AAM34790.1|AF512560_2  HAC4 [Arabidopsis thal...   123   5e-26
gi|7494646|pir||T37269  hypothetical protein - Caenorhabditi...   112   1e-22
gi|482238|pir||S41033  hypothetical protein K03H1.10 - Caeno...   108   1e-21
gi|17554044|ref|NP_499201.1|  CREB-binding protein like fami...   108   1e-21
gi|23664002|gb|AAN39141.1|  CREB-binding protein [Rattus nor...   105   1e-20
gi|33146482|dbj|BAC79591.1|  putative RING3 protein [Oryza s...    86   6e-15
gi|17552400|ref|NP_497145.1|  CREB-binding protein like fami...    85   1e-14
gi|29569106|gb|AAO84020.1|  global transcription factor grou...    82   1e-13
gi|17551090|ref|NP_510006.1|  CREB-binding protein like fami...    82   1e-13
gi|33417197|gb|AAH55508.1|  Unknown (protein for IMAGE:38191...    81   2e-13
gi|19171509|emb|CAC84085.1|  hypothetical protein [Takifugu ...    81   3e-13
gi|18395937|ref|NP_566151.1|  DNA-binding protein family [Ar...    80   4e-13
gi|6016737|gb|AAF01563.1|AC009325_33  hypothetical protein [...    80   4e-13
gi|7493489|pir||T40984  transcription factor bdf1 homolog SP...    80   5e-13
gi|27720883|ref|XP_236438.1|  similar to WD repeat domain 11...    80   6e-13
gi|17976800|emb|CAC83118.1|  WD repeat domain 11 protein [Ho...    80   6e-13
gi|12007334|gb|AAG45145.1|  IRS-1 PH domain binding protein ...    79   9e-13
gi|7485801|pir||T00472  probable RING3 protein [imported] - ...    79   9e-13
gi|12007336|gb|AAG45146.1|  IRS-1 PH domain binding protein ...    79   1e-12
gi|16905089|ref|NP_473395.1|  female sterile homeotic-relate...    79   1e-12
gi|30686240|ref|NP_181036.2|  RING3 protein -related [Arabid...    79   2e-12
gi|17976802|emb|CAC83119.1|  WD repeat domain 11 protein [Mu...    78   2e-12
gi|23480253|gb|EAA16864.1|  ERYTHROCYTE MEMBRANE PROTEIN PFE...    78   2e-12
gi|19173489|ref|NP_597292.1|  GENERAL TRANSCRIPTION FACTOR [...    78   2e-12
gi|1502355|emb|CAA67614.1|  GCN5 [Saccharomyces cerevisiae]        78   2e-12
gi|6321691|ref|NP_011768.1|  functions in the Ada and SAGA (...    77   3e-12
gi|15231174|ref|NP_190796.1|  hypothetical protein [Arabidop...    77   3e-12
gi|20149648|ref|NP_060404.2|  pleckstrin homology domain int...    77   3e-12
gi|16445438|ref|NP_387505.1|  WD repeat domain 9 isoform B; ...    77   3e-12
gi|23831562|sp|Q9NSI6|WDR9_HUMAN  WD-repeat protein 9 >gi|20...    77   3e-12
gi|7717364|emb|CAB90452.1|  homolog to cAMP response element...    77   3e-12
gi|7020972|dbj|BAA91336.1|  unnamed protein product [Homo sa...    77   4e-12
gi|14970564|emb|CAC44372.1|  WDR9 protein, form B [Homo sapi...    77   4e-12
gi|16445436|ref|NP_061836.2|  WD repeat domain 9 isoform A; ...    77   4e-12
gi|14970562|emb|CAC44371.1|  WDR9 protein, form A [Homo sapi...    77   5e-12
gi|15242727|ref|NP_201138.1|  DNA-binding protein family [Ar...    77   5e-12
gi|24659254|ref|NP_726307.1|  CG30417-PA [Drosophila melanog...    77   5e-12
gi|18655484|pdb|1KBH|B  Chain B, Mutual Synergistic Folding ...    77   5e-12
gi|1588281|prf||2208296A  RING3 protein                            76   7e-12
gi|27469649|gb|AAH38844.1|  Unknown (protein for IMAGE:57426...    76   7e-12
gi|25511645|pir||H86312  F2H15.2 protein - Arabidopsis thali...    76   7e-12
gi|13699186|dbj|BAB41205.1|  kinase-like protein [Oryza sativa]    76   8e-12
gi|6320132|ref|NP_010213.1|  bromodomain protein, homolog of...    76   8e-12
gi|18394534|ref|NP_564037.1|  bromodomain-containing protein...    75   1e-11
gi|33355659|gb|AAQ16198.1|  testis-specific BRDT protein [Ho...    75   1e-11
gi|11513447|pdb|1E6I|A  Chain A, Bromodomain From Gcn5 Compl...    75   1e-11
gi|27692264|ref|XP_223146.1|  similar to testis-specific bro...    75   1e-11
gi|22761009|dbj|BAC11417.1|  unnamed protein product [Homo s...    75   1e-11
gi|24210305|emb|CAD54663.1|  SI:dZ12F11.5 (bromodomain-conta...    75   2e-11
gi|24649631|ref|NP_732982.1|  CG31132-PA [Drosophila melanog...    75   2e-11
gi|23508824|ref|NP_701492.1|  bromodomain protein, putative ...    75   2e-11
gi|15810439|gb|AAL07107.1|  unknown protein [Arabidopsis tha...    75   2e-11

Alignments

>gi|1345703|sp|P45481|CBP_MOUSE CREB-binding protein
 gi|481698|pir||S39161 CREB-binding protein - mouse
 gi|435855|gb|AAB28651.1| CREB-binding protein; CBP [Mus sp.]
          Length = 2441

 Score = 3467 bits (8991), Expect = 0.0
 Identities = 1964/2441 (80%), Positives = 1964/2441 (80%)

Query: 1    MAENLLDGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIPXXXXXXXXXXXXVP 60
            MAENLLDGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIP            VP
Sbjct: 1    MAENLLDGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIPNGELSLLNSGNLVP 60

Query: 61   DAASKHKQLSELLRXXXXXXXXXXXXXXXASSPVXXXXXXXXXXXPNSTNMASLGAMGKS 120
            DAASKHKQLSELLR               ASSPV           PNSTNMASLGAMGKS
Sbjct: 61   DAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSTNMASLGAMGKS 120

Query: 121  PLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANF 180
            PLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANF
Sbjct: 121  PLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANF 180

Query: 181  NQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLXXXXXXXXXXXXXXXXXXXXXTSSVLAE 240
            NQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSL                     TSSVLAE
Sbjct: 181  NQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLGAAGRGRGAGMPYPAPAMQGATSSVLAE 240

Query: 241  TLTQVSPQMAGHAGLNTAQAXXXXXXXXXXXXSPFGQPFSQTGGQQMGATGVNPQLASKQ 300
            TLTQVSPQMAGHAGLNTAQA            SPFGQPFSQTGGQQMGATGVNPQLASKQ
Sbjct: 241  TLTQVSPQMAGHAGLNTAQAGGMTKMGMTGTTSPFGQPFSQTGGQQMGATGVNPQLASKQ 300

Query: 301  SMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLL 360
            SMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLL
Sbjct: 301  SMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLL 360

Query: 361  LHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQIISHWKN 420
            LHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQIISHWKN
Sbjct: 361  LHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQIISHWKN 420

Query: 421  CTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSM 480
            CTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSM
Sbjct: 421  CTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSM 480

Query: 481  QRAYAALGLPYMNXXXXXXXXXXXXXXXXXXXXXXXMRTLNALGNNPMSVPAGGITTDQQ 540
            QRAYAALGLPYMN                       MRTLNALGNNPMSVPAGGITTDQQ
Sbjct: 481  QRAYAALGLPYMNQPQTQLQPQVPGQQPAQPPAHQQMRTLNALGNNPMSVPAGGITTDQQ 540

Query: 541  PPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLR 600
            PPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLR
Sbjct: 541  PPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLR 600

Query: 601  SHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKI 660
            SHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKI
Sbjct: 601  SHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKI 660

Query: 661  QKELEEKRRTRLHKQGILGNQPALPASGAQPPVIPPAQSVRPPNGPLPLPVNRMQVSQGM 720
            QKELEEKRRTRLHKQGILGNQPALPASGAQPPVIPPAQSVRPPNGPLPLPVNRMQVSQGM
Sbjct: 661  QKELEEKRRTRLHKQGILGNQPALPASGAQPPVIPPAQSVRPPNGPLPLPVNRMQVSQGM 720

Query: 721  NSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHAN 780
            NSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHAN
Sbjct: 721  NSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHAN 780

Query: 781  NIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQEPGAALPNPLNMLAP 840
            NIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQEPGAALPNPLNMLAP
Sbjct: 781  NIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQEPGAALPNPLNMLAP 840

Query: 841  QASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHXXXXXXXXXXXXXXXXXXXXVSSGQTP 900
            QASQLPCPPVTQSPLHPTPPPASTAAGMPSLQH                    VSSGQTP
Sbjct: 841  QASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHPTAPGMTPPQPAAPTQPSTPVSSGQTP 900

Query: 901  TPTPGSVPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGT 960
            TPTPGSVP                                                  GT
Sbjct: 901  TPTPGSVPSAAQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHTQPPGT 960

Query: 961  PLSQAAASIDNRVPTPSTVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRS 1020
            PLSQAAASIDNRVPTPSTVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRS
Sbjct: 961  PLSQAAASIDNRVPTPSTVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRS 1020

Query: 1021 EMMEEDLQGSSQVKEETDTTEQKSXXXXXXXXXXXXXXXXXXXXXNSSNDTASQSTSPSQ 1080
            EMMEEDLQGSSQVKEETDTTEQKS                     NSSNDTASQSTSPSQ
Sbjct: 1021 EMMEEDLQGSSQVKEETDTTEQKSEPMEVEEKKPEVKVEAKEEEENSSNDTASQSTSPSQ 1080

Query: 1081 PRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIK 1140
            PRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIK
Sbjct: 1081 PRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIK 1140

Query: 1141 RKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYC 1200
            RKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYC
Sbjct: 1141 RKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYC 1200

Query: 1201 CGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCGKCFTEIQGENVTLGDDPSQPQ 1260
            CGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCGKCFTEIQGENVTLGDDPSQPQ
Sbjct: 1201 CGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCGKCFTEIQGENVTLGDDPSQPQ 1260

Query: 1261 TTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPR 1320
            TTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPR
Sbjct: 1261 TTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPR 1320

Query: 1321 KENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRF 1380
            KENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRF
Sbjct: 1321 KENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRF 1380

Query: 1381 VDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSIHF 1440
            VDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSIHF
Sbjct: 1381 VDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSIHF 1440

Query: 1441 FRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRL 1500
            FRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRL
Sbjct: 1441 FRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRL 1500

Query: 1501 QEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLXXXXXXXXXX 1560
            QEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVL          
Sbjct: 1501 QEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQE 1560

Query: 1561 XXXXXXXXXXXXXXTPEGSQGDSXXXXXXXXXXXXXXXSSISRANKKKPSMPNVSNDLSQ 1620
                          TPEGSQGDS               SSISRANKKKPSMPNVSNDLSQ
Sbjct: 1561 EEERKKEESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQ 1620

Query: 1621 KLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFS 1680
            KLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFS
Sbjct: 1621 KLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFS 1680

Query: 1681 SLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHT 1740
            SLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHT
Sbjct: 1681 SLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHT 1740

Query: 1741 HKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMK 1800
            HKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMK
Sbjct: 1741 HKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMK 1800

Query: 1801 RVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHNVRXXXXXXXX 1860
            RVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHNVR        
Sbjct: 1801 RVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHNVRQQQIQHCL 1860

Query: 1861 XXXXLXXXXXXXXXXXXVPQQSLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVNMSPA 1920
                L            VPQQSL                               VNMSPA
Sbjct: 1861 QQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVNMSPA 1920

Query: 1921 GFPNVARTQPPTIVSAGKPTNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHLYRANINN 1980
            GFPNVARTQPPTIVSAGKPTN                              HLYRANINN
Sbjct: 1921 GFPNVARTQPPTIVSAGKPTNQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRANINN 1980

Query: 1981 GMPPGRDGMGTPGSQMTPVGLNVPRPNQVSGPVMSSMXXXXXXXXXXXXXXXXXXXXXXV 2040
            GMPPGRDGMGTPGSQMTPVGLNVPRPNQVSGPVMSSM                      V
Sbjct: 1981 GMPPGRDGMGTPGSQMTPVGLNVPRPNQVSGPVMSSMPPGQWQQAPIPQQQPMPGMPRPV 2040

Query: 2041 MSMQAQAAVAGPRMPNVQPNRSISPSALQDLLRTLKXXXXXXXXXXVLNILKSNPQLMAA 2100
            MSMQAQAAVAGPRMPNVQPNRSISPSALQDLLRTLK          VLNILKSNPQLMAA
Sbjct: 2041 MSMQAQAAVAGPRMPNVQPNRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAA 2100

Query: 2101 FIKQRTAKYVANXXXXXXXXXXXXXXXXXXXXXXXXXXSLQNLNAMXXXXXXXXXXXXXX 2160
            FIKQRTAKYVAN                          SLQNLNAM              
Sbjct: 2101 FIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPPQP 2160

Query: 2161 XMGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRRXXXXXXXXXXXXXXXXXXXXNSAS 2220
             MGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRR                    NSAS
Sbjct: 2161 AMGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRRQLLQHQQQQQQQQQQQQQQQNSAS 2220

Query: 2221 LAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSXXXXXXXXXXXXXXXXXXXXA 2280
            LAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSS                    A
Sbjct: 2221 LAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSMGQMAAPMGQLGQMGQPGLGA 2280

Query: 2281 DSTPNXXXXXXXXXXXXXXXXXXXGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSN 2340
            DSTPN                   GSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSN
Sbjct: 2281 DSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSN 2340

Query: 2341 QVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGTPHPGLAVTMASSMDQGHLG 2400
            QV                                    TGTPHPGLAVTMASSMDQGHLG
Sbjct: 2341 QVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGTPHPGLAVTMASSMDQGHLG 2400

Query: 2401 NPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL 2441
            NPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL
Sbjct: 2401 NPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL 2441



>gi|737920|prf||1923401A protein CBP
          Length = 2441

 Score = 3465 bits (8984), Expect = 0.0
 Identities = 1963/2441 (80%), Positives = 1963/2441 (80%)

Query: 1    MAENLLDGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIPXXXXXXXXXXXXVP 60
            MAENLLDGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIP            VP
Sbjct: 1    MAENLLDGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIPNGELSLLNSGNLVP 60

Query: 61   DAASKHKQLSELLRXXXXXXXXXXXXXXXASSPVXXXXXXXXXXXPNSTNMASLGAMGKS 120
            DAASKHKQLSELLR               ASSPV           PNSTNMASLGAMGKS
Sbjct: 61   DAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSTNMASLGAMGKS 120

Query: 121  PLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANF 180
            PLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANF
Sbjct: 121  PLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANF 180

Query: 181  NQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLXXXXXXXXXXXXXXXXXXXXXTSSVLAE 240
            NQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSL                     TSSVLAE
Sbjct: 181  NQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLGAAGRGRGAGMPYPAPAMQGATSSVLAE 240

Query: 241  TLTQVSPQMAGHAGLNTAQAXXXXXXXXXXXXSPFGQPFSQTGGQQMGATGVNPQLASKQ 300
            TLTQVSPQMAGHAGLNTAQA            SPFGQPFSQTGGQQMGATGVNPQLASKQ
Sbjct: 241  TLTQVSPQMAGHAGLNTAQAGGMTKMGMTGTTSPFGQPFSQTGGQQMGATGVNPQLASKQ 300

Query: 301  SMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLL 360
            SMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLL
Sbjct: 301  SMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLL 360

Query: 361  LHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQIISHWKN 420
            LHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQIISHWKN
Sbjct: 361  LHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQIISHWKN 420

Query: 421  CTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSM 480
            CTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSM
Sbjct: 421  CTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSM 480

Query: 481  QRAYAALGLPYMNXXXXXXXXXXXXXXXXXXXXXXXMRTLNALGNNPMSVPAGGITTDQQ 540
            QRAYAALGLPYMN                       MRTLNALGNNPMSVPAGGITTDQQ
Sbjct: 481  QRAYAALGLPYMNQPQTQLQPQVPGQQPAQPPAHQQMRTLNALGNNPMSVPAGGITTDQQ 540

Query: 541  PPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLR 600
            PPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHE VTQDLR
Sbjct: 541  PPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHERVTQDLR 600

Query: 601  SHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKI 660
            SHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKI
Sbjct: 601  SHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKI 660

Query: 661  QKELEEKRRTRLHKQGILGNQPALPASGAQPPVIPPAQSVRPPNGPLPLPVNRMQVSQGM 720
            QKELEEKRRTRLHKQGILGNQPALPASGAQPPVIPPAQSVRPPNGPLPLPVNRMQVSQGM
Sbjct: 661  QKELEEKRRTRLHKQGILGNQPALPASGAQPPVIPPAQSVRPPNGPLPLPVNRMQVSQGM 720

Query: 721  NSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHAN 780
            NSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHAN
Sbjct: 721  NSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHAN 780

Query: 781  NIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQEPGAALPNPLNMLAP 840
            NIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQEPGAALPNPLNMLAP
Sbjct: 781  NIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQEPGAALPNPLNMLAP 840

Query: 841  QASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHXXXXXXXXXXXXXXXXXXXXVSSGQTP 900
            QASQLPCPPVTQSPLHPTPPPASTAAGMPSLQH                    VSSGQTP
Sbjct: 841  QASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHPTAPGMTPPQPAAPTQPSTPVSSGQTP 900

Query: 901  TPTPGSVPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGT 960
            TPTPGSVP                                                  GT
Sbjct: 901  TPTPGSVPSAAQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHTQPPGT 960

Query: 961  PLSQAAASIDNRVPTPSTVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRS 1020
            PLSQAAASIDNRVPTPSTVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRS
Sbjct: 961  PLSQAAASIDNRVPTPSTVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRS 1020

Query: 1021 EMMEEDLQGSSQVKEETDTTEQKSXXXXXXXXXXXXXXXXXXXXXNSSNDTASQSTSPSQ 1080
            EMMEEDLQGSSQVKEETDTTEQKS                     NSSNDTASQSTSPSQ
Sbjct: 1021 EMMEEDLQGSSQVKEETDTTEQKSEPMEVEEKKPEVKVEAKEEEENSSNDTASQSTSPSQ 1080

Query: 1081 PRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIK 1140
            PRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIK
Sbjct: 1081 PRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIK 1140

Query: 1141 RKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYC 1200
            RKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYC
Sbjct: 1141 RKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYC 1200

Query: 1201 CGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCGKCFTEIQGENVTLGDDPSQPQ 1260
            CGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCGKCFTEIQGENVTLGDDPSQPQ
Sbjct: 1201 CGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCGKCFTEIQGENVTLGDDPSQPQ 1260

Query: 1261 TTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPR 1320
            TTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPR
Sbjct: 1261 TTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPR 1320

Query: 1321 KENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRF 1380
            KENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRF
Sbjct: 1321 KENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRF 1380

Query: 1381 VDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSIHF 1440
            VDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSIHF
Sbjct: 1381 VDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSIHF 1440

Query: 1441 FRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRL 1500
            FRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRL
Sbjct: 1441 FRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRL 1500

Query: 1501 QEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLXXXXXXXXXX 1560
            QEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVL          
Sbjct: 1501 QEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQE 1560

Query: 1561 XXXXXXXXXXXXXXTPEGSQGDSXXXXXXXXXXXXXXXSSISRANKKKPSMPNVSNDLSQ 1620
                          TPEGSQGDS               SSISRANKKKPSMPNVSNDLSQ
Sbjct: 1561 EEERKKEESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQ 1620

Query: 1621 KLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFS 1680
            KLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFS
Sbjct: 1621 KLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFS 1680

Query: 1681 SLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHT 1740
            SLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHT
Sbjct: 1681 SLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHT 1740

Query: 1741 HKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMK 1800
            HKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMK
Sbjct: 1741 HKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMK 1800

Query: 1801 RVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHNVRXXXXXXXX 1860
            RVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHNVR        
Sbjct: 1801 RVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHNVRQQQIQHCL 1860

Query: 1861 XXXXLXXXXXXXXXXXXVPQQSLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVNMSPA 1920
                L            VPQQSL                               VNMSPA
Sbjct: 1861 QQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVNMSPA 1920

Query: 1921 GFPNVARTQPPTIVSAGKPTNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHLYRANINN 1980
            GFPNVARTQPPTIVSAGKPTN                              HLYRANINN
Sbjct: 1921 GFPNVARTQPPTIVSAGKPTNQVPAPPPPAPQQQAAVEAARQIEREAQQQQHLYRANINN 1980

Query: 1981 GMPPGRDGMGTPGSQMTPVGLNVPRPNQVSGPVMSSMXXXXXXXXXXXXXXXXXXXXXXV 2040
            GMPPGRDGMGTPGSQMTPVGLNVPRPNQVSGPVMSSM                      V
Sbjct: 1981 GMPPGRDGMGTPGSQMTPVGLNVPRPNQVSGPVMSSMPPGQWQQAPIPQQQPMPGMPRPV 2040

Query: 2041 MSMQAQAAVAGPRMPNVQPNRSISPSALQDLLRTLKXXXXXXXXXXVLNILKSNPQLMAA 2100
            MSMQAQAAVAGPRMPNVQPNRSISPSALQDLLRTLK          VLNILKSNPQLMAA
Sbjct: 2041 MSMQAQAAVAGPRMPNVQPNRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAA 2100

Query: 2101 FIKQRTAKYVANXXXXXXXXXXXXXXXXXXXXXXXXXXSLQNLNAMXXXXXXXXXXXXXX 2160
            FIKQRTAKYVAN                          SLQNLNAM              
Sbjct: 2101 FIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPPQP 2160

Query: 2161 XMGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRRXXXXXXXXXXXXXXXXXXXXNSAS 2220
             MGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRR                    NSAS
Sbjct: 2161 AMGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRRQLLQHQQQQQQQQQQQQQQQNSAS 2220

Query: 2221 LAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSXXXXXXXXXXXXXXXXXXXXA 2280
            LAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSS                    A
Sbjct: 2221 LAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSMGQMAAPMGQLGQMGQPGLGA 2280

Query: 2281 DSTPNXXXXXXXXXXXXXXXXXXXGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSN 2340
            DSTPN                   GSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSN
Sbjct: 2281 DSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSN 2340

Query: 2341 QVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGTPHPGLAVTMASSMDQGHLG 2400
            QV                                    TGTPHPGLAVTMASSMDQGHLG
Sbjct: 2341 QVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGTPHPGLAVTMASSMDQGHLG 2400

Query: 2401 NPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL 2441
            NPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL
Sbjct: 2401 NPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL 2441



>gi|19547885|gb|AAL87531.1| CREB-binding protein [Mus musculus]
 gi|19547887|gb|AAL87532.1| CREB-binding protein [Mus musculus]
          Length = 2429

 Score = 3387 bits (8781), Expect = 0.0
 Identities = 1926/2429 (79%), Positives = 1932/2429 (79%)

Query: 7    DGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIPXXXXXXXXXXXXVPDAASKH 66
            DGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIP            VPDAASKH
Sbjct: 1    DGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIPNGELSLLNSGNLVPDAASKH 60

Query: 67   KQLSELLRXXXXXXXXXXXXXXXASSPVXXXXXXXXXXXPNSTNMASLGAMGKSPLNQGD 126
            KQLSELLR               ASSPV           PNSTNMASLGAMGKSPLNQGD
Sbjct: 61   KQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSTNMASLGAMGKSPLNQGD 120

Query: 127  SSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANFNQTHPG 186
            SSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANFNQTHPG
Sbjct: 121  SSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANFNQTHPG 180

Query: 187  LLNSNSGHSLMNQAQQGQAQVMNGSLXXXXXXXXXXXXXXXXXXXXXTSSVLAETLTQVS 246
            LLNSNSGHSLMNQAQQGQAQVMNGSL                     TSSVLAETLTQVS
Sbjct: 181  LLNSNSGHSLMNQAQQGQAQVMNGSLGAAGRGRGAGMPYPAPAMQGATSSVLAETLTQVS 240

Query: 247  PQMAGHAGLNTAQAXXXXXXXXXXXXSPFGQPFSQTGGQQMGATGVNPQLASKQSMVNSL 306
            PQMAGHAGLNTAQA            SPFGQPFSQTGGQQMGATGVNPQLASKQSMVNSL
Sbjct: 241  PQMAGHAGLNTAQAGGMTKMGMTGTTSPFGQPFSQTGGQQMGATGVNPQLASKQSMVNSL 300

Query: 307  PAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKC 366
            PAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKC
Sbjct: 301  PAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKC 360

Query: 367  QRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQIISHWKNCTRHDC 426
            QRREQANGEVRACSLPHCRTMKNVLNHMTHCQA KACQVAHCASSRQIISHWKNCTRHDC
Sbjct: 361  QRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDC 420

Query: 427  PVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSMQRAYAA 486
            PVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSMQRAYAA
Sbjct: 421  PVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSMQRAYAA 480

Query: 487  LGLPYMNXXXXXXXXXXXXXXXXXXXXXXXMRTLNALGNNPMSVPAGGITTDQQPPNLIS 546
            LGLPYMN                       MRTLNALGNNPMS+PAGGITTDQQPPNLIS
Sbjct: 481  LGLPYMNQPQTQLQPQVPGQQPAQPPAHQQMRTLNALGNNPMSIPAGGITTDQQPPNLIS 540

Query: 547  ESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHK 606
            ESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHK
Sbjct: 541  ESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHK 600

Query: 607  LVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEE 666
            LVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEE
Sbjct: 601  LVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEE 660

Query: 667  KRRTRLHKQGILGNQPALPASGAQPPVIPPAQSVRPPNGPLPLPVNRMQVSQGMNSFNPM 726
            KRR+RLHKQGILGNQPALPASGAQPPVIPPAQSVRPPNGPLPLPVNRMQVSQGMNSFNPM
Sbjct: 661  KRRSRLHKQGILGNQPALPASGAQPPVIPPAQSVRPPNGPLPLPVNRMQVSQGMNSFNPM 720

Query: 727  SLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHANNIMAQA 786
            SLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHANNIMAQA
Sbjct: 721  SLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHANNIMAQA 780

Query: 787  PTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQEPGAALPNPLNMLAPQASQLP 846
            PTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQ PGAALPNPLNMLAPQASQLP
Sbjct: 781  PTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQVPGAALPNPLNMLAPQASQLP 840

Query: 847  CPPVTQSPLHPTPPPASTAAGMPSLQHXXXXXXXXXXXXXXXXXXXXVSSGQTPTPTPGS 906
            CPPVTQSPLHPTPPPASTAAGMPSLQH                    VSSGQTPTPTPGS
Sbjct: 841  CPPVTQSPLHPTPPPASTAAGMPSLQHPTAPGMTPPQPAAPTQPSTPVSSGQTPTPTPGS 900

Query: 907  VPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGTPLSQAA 966
            VP                                                  GTPLSQAA
Sbjct: 901  VPSAAQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHTQPPGTPLSQAA 960

Query: 967  ASIDNRVPTPSTVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRSEMMEED 1026
            ASIDNRVPTPS+VTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRSEMMEED
Sbjct: 961  ASIDNRVPTPSSVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRSEMMEED 1020

Query: 1027 LQGSSQVKEETDTTEQKSXXXXXXXXXXXXXXXXXXXXXNSSNDTASQSTSPSQPRKKIF 1086
            LQGSSQVKEETDTTEQKS                     NSSNDTASQSTSPSQPRKKIF
Sbjct: 1021 LQGSSQVKEETDTTEQKSEPMEVEEKKPEVKVEAKEEEENSSNDTASQSTSPSQPRKKIF 1080

Query: 1087 KPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTG 1146
            KPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTG
Sbjct: 1081 KPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTG 1140

Query: 1147 QYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYE 1206
            QYQEPWQYVDDV LMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYE
Sbjct: 1141 QYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYE 1200

Query: 1207 FSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCGKCFTEIQGENVTLGDDPSQPQTTISKD 1266
            FSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFC KCFTEIQGENVTLGDDPSQPQTTISKD
Sbjct: 1201 FSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKD 1260

Query: 1267 QFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFS 1326
            QFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFS
Sbjct: 1261 QFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFS 1320

Query: 1327 AKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEM 1386
            AKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEM
Sbjct: 1321 AKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEM 1380

Query: 1387 SESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSIHFFRPRCL 1446
            SESFPYRTKALFAFEEIDGVDVCFFGMHVQ+     P      VYISYLDSIHFFRPRCL
Sbjct: 1381 SESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCL 1440

Query: 1447 RTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKK 1506
            RTAVYHEILIGYLEYVKKL YVT HIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKK
Sbjct: 1441 RTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKK 1500

Query: 1507 MLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLXXXXXXXXXXXXXXXX 1566
            MLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVL                
Sbjct: 1501 MLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKK 1560

Query: 1567 XXXXXXXXTPEGSQGDSXXXXXXXXXXXXXXXSSISRANKKKPSMPNVSNDLSQKLYATM 1626
                    TPEGSQGDS               SSISRANKKKPSMPNVSNDLSQKLYATM
Sbjct: 1561 EESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATM 1620

Query: 1627 EKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSK 1686
            EKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSK
Sbjct: 1621 EKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSK 1680

Query: 1687 WSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKW 1746
            WSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKW
Sbjct: 1681 WSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKW 1740

Query: 1747 GLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHT 1806
            GLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHT
Sbjct: 1741 GLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHT 1800

Query: 1807 KGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHNVRXXXXXXXXXXXXLX 1866
            KGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKH +R            L 
Sbjct: 1801 KGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLM 1860

Query: 1867 XXXXXXXXXXXVPQQSLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVNMSPAGFPNVA 1926
                       VPQQSL                               VNMSPAGFPNVA
Sbjct: 1861 RRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVNMSPAGFPNVA 1920

Query: 1927 RTQPPTIVSAGKPTNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHLYRANINNGMPPGR 1986
            RTQPPTIVSAGKPTN                              HLYRANINNGMPPGR
Sbjct: 1921 RTQPPTIVSAGKPTNQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRANINNGMPPGR 1980

Query: 1987 DGMGTPGSQMTPVGLNVPRPNQVSGPVMSSMXXXXXXXXXXXXXXXXXXXXXXVMSMQAQ 2046
             GMGTPGSQMTPVGLNVPRPNQVSGPVMSSM                      VMSMQAQ
Sbjct: 1981 AGMGTPGSQMTPVGLNVPRPNQVSGPVMSSMPPGQWQQAPIPQQQPMPGMPRPVMSMQAQ 2040

Query: 2047 AAVAGPRMPNVQPNRSISPSALQDLLRTLKXXXXXXXXXXVLNILKSNPQLMAAFIKQRT 2106
            AAVAGPRMPNVQP RSISPSALQDLLRTLK          VLNILKSNPQLMAAFIKQRT
Sbjct: 2041 AAVAGPRMPNVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRT 2100

Query: 2107 AKYVANXXXXXXXXXXXXXXXXXXXXXXXXXXSLQNLNAMXXXXXXXXXXXXXXXMGGLN 2166
            AKYVAN                          SLQNLNAM               MGGLN
Sbjct: 2101 AKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPPQPAMGGLN 2160

Query: 2167 PQGQALNIMNPGHNPNMTNMNPQYREMVRRXXXXXXXXXXXXXXXXXXXXNSASLAGGMA 2226
            PQGQALNIMNPGHNPNMTNMNPQYREMVRR                    NSASLAGGMA
Sbjct: 2161 PQGQALNIMNPGHNPNMTNMNPQYREMVRRQLLQHQQQQQQQQQQQQQQQNSASLAGGMA 2220

Query: 2227 GHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSXXXXXXXXXXXXXXXXXXXXADSTPNX 2286
            GHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSS                    ADSTPN 
Sbjct: 2221 GHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSMGQMAAPMGQLGQMGQPGLGADSTPNI 2280

Query: 2287 XXXXXXXXXXXXXXXXXXGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVXXXX 2346
                              GSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQV    
Sbjct: 2281 QQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPA 2340

Query: 2347 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGTPHPGLAVTMASSMDQGHLGNPEQSA 2406
                                            TG+PHPGLAVTMASSMDQGHLGNPEQSA
Sbjct: 2341 PVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSMDQGHLGNPEQSA 2400

Query: 2407 MLPQLNTPNRSALSSELSLVGDTTGDTLE 2435
            MLPQLNTPNRSALSSELSLVGDTTGDTLE
Sbjct: 2401 MLPQLNTPNRSALSSELSLVGDTTGDTLE 2429



>gi|631119|pir||S39162 transcription coactivator CREB-binding protein - human
          Length = 2440

 Score = 3359 bits (8710), Expect = 0.0
 Identities = 1908/2443 (78%), Positives = 1926/2443 (78%), Gaps = 5/2443 (0%)

Query: 1    MAENLLDGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIP-XXXXXXXXXXXXV 59
            MAENLLDGPPNPKRAKLSSPGFSAN NTDFGSLFDLENDLPDELIP             V
Sbjct: 1    MAENLLDGPPNPKRAKLSSPGFSANSNTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV 60

Query: 60   PDAASKHKQLSELLRXXXXXXXXXXXXXXXASSPVXXXXXXXXXXXPNSTNMASLGAMGK 119
            PDAASKHKQLSELLR               ASSPV           PNS NMASL AMGK
Sbjct: 61   PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK 120

Query: 120  SPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNAN 179
            SPL+QGDSS+P+LPKQAASTSGPTP ASQALNPQAQKQVGL TSSPATSQTGPGICMNAN
Sbjct: 121  SPLSQGDSSSPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN 180

Query: 180  FNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLXXXXXXXXXXXXXXXXXXXXXTSSVLA 239
            FNQTHPGLLNSNSGHSL+NQA QGQAQVMNGSL                     +SSVLA
Sbjct: 181  FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYTAPAMQGASSSVLA 240

Query: 240  ETLTQVSPQMAGHAGLNTAQAXXXXXXXXXXXXSPFGQPFSQTGGQQMGATGVNPQLASK 299
            ETLTQVSPQ AGHAGLNTAQA            SPFGQPFSQ GGQ MGATGVNPQLASK
Sbjct: 241  ETLTQVSPQTAGHAGLNTAQAGGMAKIGMNGTTSPFGQPFSQAGGQPMGATGVNPQLASK 300

Query: 300  QSMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL 359
            QSMVNSLP FPTDIKNTSVT VPNMSQ+QTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
Sbjct: 301  QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL 360

Query: 360  LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQIISHWK 419
            LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQA KACQVAHCASSRQIISHWK
Sbjct: 361  LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK 420

Query: 420  NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSS 479
            NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVG GQQNATSLSNPNPIDPSS
Sbjct: 421  NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS 480

Query: 480  MQRAYAALGLPYMNXXXXXXXXXXXXXXXXXXXXXXXMRTLNALGNNPMSVPAGGITTDQ 539
            MQRAYAALGLPYMN                       MRTLN LGNNPM++PAGGITTDQ
Sbjct: 481  MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ 540

Query: 540  QPPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDL 599
            QPPNLISESALPTSLGATNPLMNDGSNSGNIG+LSTIPTAAPPSSTGVRKGWHEHVTQDL
Sbjct: 541  QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL 600

Query: 600  RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK 659
            RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
Sbjct: 601  RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK 660

Query: 660  IQKELEEKRRTRLHKQGILGNQPALPASGAQPPVIPPAQSVRPPNGPLPLPVNRMQVSQG 719
            IQKELEEKRR+RLHKQGILGNQPALPA GAQPPVIP AQSVRPPNGPL LPVNRMQVSQG
Sbjct: 661  IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQSVRPPNGPLSLPVNRMQVSQG 720

Query: 720  MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHA 779
            MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSM SVPGMAISPSRMPQPPNMMG H 
Sbjct: 721  MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT 780

Query: 780  NNIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQEPGAALPNPLNMLA 839
            NN+MAQAP Q+QFLPQNQFPSSSGAM   SVGMGQP AQ GVSQGQ PGAALPNPLNML 
Sbjct: 781  NNMMAQAPAQSQFLPQNQFPSSSGAM---SVGMGQPPAQTGVSQGQVPGAALPNPLNMLG 837

Query: 840  PQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHXXXXXXXXXXXXXXXXXXXXV-SSGQ 898
            PQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQH                    V SSGQ
Sbjct: 838  PQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQ 897

Query: 899  TPTPTPGSVPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 958
            TPTPTPGSVP                                                  
Sbjct: 898  TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPP 957

Query: 959  GTPLSQAAASIDNRVPTPSTVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEP 1018
            GTPLSQAAASIDNRVPTPSTV SAET+SQQPGPDVP+LEMKTE Q +D EP+P ESKGEP
Sbjct: 958  GTPLSQAAASIDNRVPTPSTVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEP 1017

Query: 1019 RSEMMEEDLQGSSQVKEETDTTEQKSXXXXXXXXXXXXXXXXXXXXXNSSNDTASQSTSP 1078
            RSEMMEEDLQG+SQVKEETD  EQKS                     +SSN TASQSTSP
Sbjct: 1018 RSEMMEEDLQGASQVKEETDIAEQKSEPMEVEDKKPEVKVEVKEEEESSSNGTASQSTSP 1077

Query: 1079 SQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLST 1138
            SQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLST
Sbjct: 1078 SQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLST 1137

Query: 1139 IKRKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG 1198
            IKRKLDTGQYQEPWQYVDDV LMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG
Sbjct: 1138 IKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG 1197

Query: 1199 YCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCGKCFTEIQGENVTLGDDPSQ 1258
            YCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFC KCFTEIQGENVTLGDDPSQ
Sbjct: 1198 YCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQ 1257

Query: 1259 PQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGR 1318
            PQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGR
Sbjct: 1258 PQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGR 1317

Query: 1319 PRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKS 1378
            PRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKS
Sbjct: 1318 PRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKS 1377

Query: 1379 RFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSI 1438
            RFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSI
Sbjct: 1378 RFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSI 1437

Query: 1439 HFFRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPK 1498
            HFFRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPK
Sbjct: 1438 HFFRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPK 1497

Query: 1499 RLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLXXXXXXXX 1558
            RLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVL        
Sbjct: 1498 RLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELE 1557

Query: 1559 XXXXXXXXXXXXXXXXTPEGSQGDSXXXXXXXXXXXXXXXSSISRANKKKPSMPNVSNDL 1618
                            TPEGSQGDS               SSISRANKKKPSMPNVSNDL
Sbjct: 1558 QEEEERKKEESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDL 1617

Query: 1619 SQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWE 1678
            SQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWE
Sbjct: 1618 SQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWE 1677

Query: 1679 FSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKS 1738
            FSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKS
Sbjct: 1678 FSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKS 1737

Query: 1739 HTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQK 1798
            HTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQK
Sbjct: 1738 HTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQK 1797

Query: 1799 MKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHNVRXXXXXX 1858
            MKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHNVR      
Sbjct: 1798 MKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHNVRQQQIQH 1857

Query: 1859 XXXXXXLXXXXXXXXXXXXVPQQSLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVNMS 1918
                  L            VPQQSL                               VNMS
Sbjct: 1858 CLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVNMS 1917

Query: 1919 PAGFPNVARTQPPTIVSAGKPTNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHLYRANI 1978
            PAGFPNVARTQPPTIVSAGKPTN                              HLYRANI
Sbjct: 1918 PAGFPNVARTQPPTIVSAGKPTNQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRANI 1977

Query: 1979 NNGMPPGRDGMGTPGSQMTPVGLNVPRPNQVSGPVMSSMXXXXXXXXXXXXXXXXXXXXX 2038
            NNGMPPGRDGMGTPGSQMTPVGLNVPRPNQVSGPVMSSM                     
Sbjct: 1978 NNGMPPGRDGMGTPGSQMTPVGLNVPRPNQVSGPVMSSMPPGQWQQAPIPQQQPMPGMPR 2037

Query: 2039 XVMSMQAQAAVAGPRMPNVQPNRSISPSALQDLLRTLKXXXXXXXXXXVLNILKSNPQLM 2098
             VMSMQAQAAVAGPRMPNVQPNRSISPSALQDLLRTLK          VLNILKSNPQLM
Sbjct: 2038 PVMSMQAQAAVAGPRMPNVQPNRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLM 2097

Query: 2099 AAFIKQRTAKYVANXXXXXXXXXXXXXXXXXXXXXXXXXXSLQNLNAMXXXXXXXXXXXX 2158
            AAFIKQRTAKYVAN                          SLQNLNAM            
Sbjct: 2098 AAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPP 2157

Query: 2159 XXXMGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRRXXXXXXXXXXXXXXXXXXXXNS 2218
               MGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRR                    NS
Sbjct: 2158 QPAMGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRRQLLQHQQQQQQQQQQQQQQQNS 2217

Query: 2219 ASLAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSXXXXXXXXXXXXXXXXXXX 2278
            ASLAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSS                   
Sbjct: 2218 ASLAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSMGQMAAPMGQLGQMGQPGL 2277

Query: 2279 XADSTPNXXXXXXXXXXXXXXXXXXXGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSL 2338
             ADSTPN                   GSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSL
Sbjct: 2278 GADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSL 2337

Query: 2339 SNQVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGTPHPGLAVTMASSMDQGH 2398
            SNQV                                    TGTPHPGLAVTMASSMDQGH
Sbjct: 2338 SNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGTPHPGLAVTMASSMDQGH 2397

Query: 2399 LGNPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL 2441
            LGNPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL
Sbjct: 2398 LGNPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL 2440



>gi|4321116|gb|AAC51331.2| CREB-binding protein [Homo sapiens]
          Length = 2442

 Score = 3214 bits (8334), Expect = 0.0
 Identities = 1857/2445 (75%), Positives = 1892/2445 (77%), Gaps = 7/2445 (0%)

Query: 1    MAENLLDGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIP-XXXXXXXXXXXXV 59
            MAENLLDGPPNPKRAKLSSPGFSAND+TDFGSLFDLENDLPDELIP             V
Sbjct: 1    MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV 60

Query: 60   PDAASKHKQLSELLRXXXXXXXXXXXXXXXASSPVXXXXXXXXXXXPNSTNMASLGAMGK 119
            PDAASKHKQLSELLR               ASSPV           PNS NMASL AMGK
Sbjct: 61   PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK 120

Query: 120  SPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNAN 179
            SPL+QGDSS P+LPKQAASTSGPTP ASQALNPQAQKQVGL TSSPATSQTGPGICMNAN
Sbjct: 121  SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN 180

Query: 180  FNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLXXXXXXXXXXXXXXXXXXXXXTSSVLA 239
            FNQTHPGLLNSNSGHSL+NQA QGQAQVMNGSL                     +SSVLA
Sbjct: 181  FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA 240

Query: 240  ETLTQVSPQMAGHAGLNTAQAXXXXXXXXXXXXSPFGQPFSQTGGQQMGATGVNPQLASK 299
            ETLTQVSPQM GHAGLNTAQA            SPFGQPFSQ GGQ MGATGVNPQLASK
Sbjct: 241  ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK 300

Query: 300  QSMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL 359
            QSMVNSLP FPTDIKNTSVT VPNMSQ+QTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
Sbjct: 301  QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL 360

Query: 360  LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQIISHWK 419
            LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQA KACQVAHCASSRQIISHWK
Sbjct: 361  LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK 420

Query: 420  NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSS 479
            NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVG GQQNATSLSNPNPIDPSS
Sbjct: 421  NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS 480

Query: 480  MQRAYAALGLPYMNXXXXXXXXXXXXXXXXXXXXXXXMRTLNALGNNPMSVPAGGITTDQ 539
            MQRAYAALGLPYMN                       MRTLN LGNNPM++PAGGITTDQ
Sbjct: 481  MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ 540

Query: 540  QPPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDL 599
            QPPNLISESALPTSLGATNPLMNDGSNSGNIG+LSTIPTAAPPSSTGVRKGWHEHVTQDL
Sbjct: 541  QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL 600

Query: 600  RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK 659
            RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
Sbjct: 601  RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK 660

Query: 660  IQKELEEKRRTRLHKQGILGNQPALPASGAQPPVIPPAQSVRPPNGPLPLPVNRMQVSQG 719
            IQKELEEKRR+RLHKQGILGNQPALPA GAQPPVIP AQ VRPPNGPL LPVNRMQVSQG
Sbjct: 661  IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG 720

Query: 720  MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHA 779
            MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSM SVPGMAISPSRMPQPPNMMG H 
Sbjct: 721  MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT 780

Query: 780  NNIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQEPGAALPNPLNMLA 839
            NN+MAQAP Q+QFLPQNQFPSSSGAM   SVGMGQP AQ GVSQGQ PGAALPNPLNML 
Sbjct: 781  NNMMAQAPAQSQFLPQNQFPSSSGAM---SVGMGQPPAQTGVSQGQVPGAALPNPLNMLG 837

Query: 840  PQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHXXXXXXXXXXXXXXXXXXXXV-SSGQ 898
            PQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQH                    V SSGQ
Sbjct: 838  PQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQ 897

Query: 899  TPTPTPGSVPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 958
            TPTPTPGSVP                                                  
Sbjct: 898  TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPP 957

Query: 959  GTPLSQAAASIDNRVPTPSTVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEP 1018
            GTPLSQAAASIDNRVPTPS+V SAET+SQQPGPDVP+LEMKTE Q +D EP+P ESKGEP
Sbjct: 958  GTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEP 1017

Query: 1019 RSEMMEEDLQGSSQVKEETDTTEQKSXXXXXXXXXXXXXXXXXXXXXNSSNDTASQSTSP 1078
            RSEMMEEDLQG+SQVKEETD  EQKS                     +SSN TASQSTSP
Sbjct: 1018 RSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSP 1077

Query: 1079 SQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLST 1138
            SQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLST
Sbjct: 1078 SQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLST 1137

Query: 1139 IKRKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG 1198
            IKRKLDTGQYQEPWQYVDDV LMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG
Sbjct: 1138 IKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG 1197

Query: 1199 YCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCGKCFTEIQGENVTLGDDPSQ 1258
            YCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFC KCFTEIQGENVTLGDDPSQ
Sbjct: 1198 YCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQ 1257

Query: 1259 PQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGR 1318
            PQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGR
Sbjct: 1258 PQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGR 1317

Query: 1319 PRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKS 1378
            PRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKS
Sbjct: 1318 PRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKS 1377

Query: 1379 RFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSI 1438
            RFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQ+     P      VYISYLDSI
Sbjct: 1378 RFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSI 1437

Query: 1439 HFFRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPK 1498
            HFFRPRCLRTAVYHEILIGYLEYVKKL YVT HIWACPPSEGDDYIFHCHPPDQKIPKPK
Sbjct: 1438 HFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPK 1497

Query: 1499 RLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLXXXXXXXX 1558
            RLQEWYKKMLDKAFAERII+DYKDIFKQA EDRLTSAKELPYFEGDFWPNVL        
Sbjct: 1498 RLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELE 1557

Query: 1559 XXXXXXXXXXXXXXXXTPEGSQGDSXXXXXXXXXXXXXXXSSISRANKKKPSMPNVSNDL 1618
                            T EGSQGDS               SSISRANKKKPSMPNVSNDL
Sbjct: 1558 QEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDL 1617

Query: 1619 SQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWE 1678
            SQKLYATMEKHKEVFFVIHLHAGPVI+T PPIVDPDPLLSCDLMDGRDAFLTLARDKHWE
Sbjct: 1618 SQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWE 1677

Query: 1679 FSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKS 1738
            FSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKS
Sbjct: 1678 FSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKS 1737

Query: 1739 HTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQK 1798
            H HKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQK
Sbjct: 1738 HAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQK 1797

Query: 1799 MKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHNVRXXXXXX 1858
            MKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKH +R      
Sbjct: 1798 MKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQH 1857

Query: 1859 XXXXXXLXXXXXXXXXXXXVPQQSLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVNMS 1918
                  L            VPQQSL                               V+MS
Sbjct: 1858 RLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMS 1917

Query: 1919 PAGFPNVARTQPPTIVSAGKPTNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHLYRANI 1978
            PAGFP+VARTQPPT VS GKPT+                              HLYR NI
Sbjct: 1918 PAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNI 1977

Query: 1979 NNGMPPGRDGMGTPGSQMTPVGLNVPRPNQVSGPVMSSMXXXXXXXXXXXXXXXXXXXXX 2038
            NN MPPGR GMGTPGSQM PV LNVPRPNQVSGPVM SM                     
Sbjct: 1978 NNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPR 2037

Query: 2039 XVMSMQAQAAVAGPRMPNVQPNRSISPSALQDLLRTLKXXXXXXXXXXVLNILKSNPQLM 2098
             V+SMQAQAAVAGPRMP+VQP RSISPSALQDLLRTLK          VLNILKSNPQLM
Sbjct: 2038 PVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLM 2097

Query: 2099 AAFIKQRTAKYVANXXXXXXXXXXXXXXXXXXXXXXXXXXSLQNLNAMXXXXXXXXXXXX 2158
            AAFIKQRTAKYVAN                          SLQNLNAM            
Sbjct: 2098 AAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQ 2157

Query: 2159 XXXMGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRR-XXXXXXXXXXXXXXXXXXXXN 2217
               MGGLNPQGQALNIMNPGHNPNM +MNPQYREM+RR                      
Sbjct: 2158 QQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQG 2217

Query: 2218 SASLAGGMAGHSQFQQPQGPGGYAPA-MQQQRMQQHLPIQGSSXXXXXXXXXXXXXXXXX 2276
            SA +AGGMAGH QFQQPQGPGGY PA  QQQRMQQHLP+QGSS                 
Sbjct: 2218 SAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQP 2277

Query: 2277 XXXADSTPNXXXXXXXXXXXXXXXXXXXGSPGQPNPMSPQQHMLSGQPQASHLPGQQIAT 2336
               ADSTPN                   GSPGQPNPMSPQQHMLSGQPQASHLPGQQIAT
Sbjct: 2278 GLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIAT 2337

Query: 2337 SLSNQVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGTPHPGLAVTMASSMDQ 2396
            SLSNQV                                    TG+PHPGLAVTMASS+DQ
Sbjct: 2338 SLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQ 2397

Query: 2397 GHLGNPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL 2441
            GHLGNPEQSAMLPQLNTP+RSALSSELSLVGDTTGDTLEKFVEGL
Sbjct: 2398 GHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL 2442



>gi|4758056|ref|NP_004371.1| CREB binding protein [Homo sapiens]
 gi|3023440|sp|Q92793|CBP_HUMAN CREB-binding protein
 gi|2443859|gb|AAC51770.1| CREB-binding protein
          Length = 2442

 Score = 3213 bits (8331), Expect = 0.0
 Identities = 1856/2445 (75%), Positives = 1892/2445 (77%), Gaps = 7/2445 (0%)

Query: 1    MAENLLDGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIP-XXXXXXXXXXXXV 59
            MAENLLDGPPNPKRAKLSSPGFSAND+TDFGSLFDLENDLPDELIP             V
Sbjct: 1    MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV 60

Query: 60   PDAASKHKQLSELLRXXXXXXXXXXXXXXXASSPVXXXXXXXXXXXPNSTNMASLGAMGK 119
            PDAASKHKQLSELLR               ASSPV           PNS NMASL AMGK
Sbjct: 61   PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK 120

Query: 120  SPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNAN 179
            SPL+QGDSS P+LPKQAASTSGPTP ASQALNPQAQKQVGL TSSPATSQTGPGICMNAN
Sbjct: 121  SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN 180

Query: 180  FNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLXXXXXXXXXXXXXXXXXXXXXTSSVLA 239
            FNQTHPGLLNSNSGHSL+NQA QGQAQVMNGSL                     +SSVLA
Sbjct: 181  FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA 240

Query: 240  ETLTQVSPQMAGHAGLNTAQAXXXXXXXXXXXXSPFGQPFSQTGGQQMGATGVNPQLASK 299
            ETLTQVSPQM GHAGLNTAQA            SPFGQPFSQ GGQ MGATGVNPQLASK
Sbjct: 241  ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK 300

Query: 300  QSMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL 359
            QSMVNSLP FPTDIKNTSVT VPNMSQ+QTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
Sbjct: 301  QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL 360

Query: 360  LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQIISHWK 419
            LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQA KACQVAHCASSRQIISHWK
Sbjct: 361  LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK 420

Query: 420  NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSS 479
            NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVG GQQNATSLSNPNPIDPSS
Sbjct: 421  NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS 480

Query: 480  MQRAYAALGLPYMNXXXXXXXXXXXXXXXXXXXXXXXMRTLNALGNNPMSVPAGGITTDQ 539
            MQRAYAALGLPYMN                       MRTLN LGNNPM++PAGGITTDQ
Sbjct: 481  MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ 540

Query: 540  QPPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDL 599
            QPPNLISESALPTSLGATNPLMNDGSNSGNIG+LSTIPTAAPPSSTGVRKGWHEHVTQDL
Sbjct: 541  QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL 600

Query: 600  RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK 659
            RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
Sbjct: 601  RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK 660

Query: 660  IQKELEEKRRTRLHKQGILGNQPALPASGAQPPVIPPAQSVRPPNGPLPLPVNRMQVSQG 719
            IQKELEEKRR+RLHKQGILGNQPALPA GAQPPVIP AQ VRPPNGPL LPVNRMQVSQG
Sbjct: 661  IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG 720

Query: 720  MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHA 779
            MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSM SVPGMAISPSRMPQPPNMMG H 
Sbjct: 721  MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT 780

Query: 780  NNIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQEPGAALPNPLNMLA 839
            NN+MAQAP Q+QFLPQNQFPSSSGAM   SVGMGQP AQ GVSQGQ PGAALPNPLNML 
Sbjct: 781  NNMMAQAPAQSQFLPQNQFPSSSGAM---SVGMGQPPAQTGVSQGQVPGAALPNPLNMLG 837

Query: 840  PQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHXXXXXXXXXXXXXXXXXXXXV-SSGQ 898
            PQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQH                    V SSGQ
Sbjct: 838  PQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQ 897

Query: 899  TPTPTPGSVPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 958
            TPTPTPGSVP                                                  
Sbjct: 898  TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPP 957

Query: 959  GTPLSQAAASIDNRVPTPSTVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEP 1018
            GTPLSQAAASIDNRVPTPS+V SAET+SQQPGPDVP+LEMKTE Q +D EP+P ESKGEP
Sbjct: 958  GTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEP 1017

Query: 1019 RSEMMEEDLQGSSQVKEETDTTEQKSXXXXXXXXXXXXXXXXXXXXXNSSNDTASQSTSP 1078
            RSEMMEEDLQG+SQVKEETD  EQKS                     +SSN TASQSTSP
Sbjct: 1018 RSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSP 1077

Query: 1079 SQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLST 1138
            SQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLST
Sbjct: 1078 SQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLST 1137

Query: 1139 IKRKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG 1198
            IKRKLDTGQYQEPWQYVDDV LMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG
Sbjct: 1138 IKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG 1197

Query: 1199 YCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCGKCFTEIQGENVTLGDDPSQ 1258
            YCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFC KCFTEIQGENVTLGDDPSQ
Sbjct: 1198 YCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQ 1257

Query: 1259 PQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGR 1318
            PQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGR
Sbjct: 1258 PQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGR 1317

Query: 1319 PRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKS 1378
            PRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKS
Sbjct: 1318 PRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKS 1377

Query: 1379 RFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSI 1438
            RFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQ+     P      VYISYLDSI
Sbjct: 1378 RFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSI 1437

Query: 1439 HFFRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPK 1498
            HFFRPRCLRTAVYHEILIGYLEYVKKL YVT HIWACPPSEGDDYIFHCHPPDQKIPKPK
Sbjct: 1438 HFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPK 1497

Query: 1499 RLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLXXXXXXXX 1558
            RLQEWYKKMLDKAFAERII+DYKDIFKQA EDRLTSAKELPYFEGDFWPNVL        
Sbjct: 1498 RLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELE 1557

Query: 1559 XXXXXXXXXXXXXXXXTPEGSQGDSXXXXXXXXXXXXXXXSSISRANKKKPSMPNVSNDL 1618
                            T EGSQGDS               SSISRANKKKPSMPNVSNDL
Sbjct: 1558 QEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDL 1617

Query: 1619 SQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWE 1678
            SQKLYATMEKHKEVFFVIHLHAGPVI+T PPIVDPDPLLSCDLMDGRDAFLTLARDKHWE
Sbjct: 1618 SQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWE 1677

Query: 1679 FSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKS 1738
            FSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKS
Sbjct: 1678 FSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKS 1737

Query: 1739 HTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQK 1798
            H HKMVKWGLGLDDEGSSQGEPQSKSPQESRR+SIQRCIQSLVHACQCRNANCSLPSCQK
Sbjct: 1738 HAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRVSIQRCIQSLVHACQCRNANCSLPSCQK 1797

Query: 1799 MKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHNVRXXXXXX 1858
            MKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKH +R      
Sbjct: 1798 MKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQH 1857

Query: 1859 XXXXXXLXXXXXXXXXXXXVPQQSLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVNMS 1918
                  L            VPQQSL                               V+MS
Sbjct: 1858 RLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMS 1917

Query: 1919 PAGFPNVARTQPPTIVSAGKPTNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHLYRANI 1978
            PAGFP+VARTQPPT VS GKPT+                              HLYR NI
Sbjct: 1918 PAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNI 1977

Query: 1979 NNGMPPGRDGMGTPGSQMTPVGLNVPRPNQVSGPVMSSMXXXXXXXXXXXXXXXXXXXXX 2038
            NN MPPGR GMGTPGSQM PV LNVPRPNQVSGPVM SM                     
Sbjct: 1978 NNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPR 2037

Query: 2039 XVMSMQAQAAVAGPRMPNVQPNRSISPSALQDLLRTLKXXXXXXXXXXVLNILKSNPQLM 2098
             V+SMQAQAAVAGPRMP+VQP RSISPSALQDLLRTLK          VLNILKSNPQLM
Sbjct: 2038 PVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLM 2097

Query: 2099 AAFIKQRTAKYVANXXXXXXXXXXXXXXXXXXXXXXXXXXSLQNLNAMXXXXXXXXXXXX 2158
            AAFIKQRTAKYVAN                          SLQNLNAM            
Sbjct: 2098 AAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQ 2157

Query: 2159 XXXMGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRR-XXXXXXXXXXXXXXXXXXXXN 2217
               MGGLNPQGQALNIMNPGHNPNM +MNPQYREM+RR                      
Sbjct: 2158 QQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQG 2217

Query: 2218 SASLAGGMAGHSQFQQPQGPGGYAPA-MQQQRMQQHLPIQGSSXXXXXXXXXXXXXXXXX 2276
            SA +AGGMAGH QFQQPQGPGGY PA  QQQRMQQHLP+QGSS                 
Sbjct: 2218 SAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQP 2277

Query: 2277 XXXADSTPNXXXXXXXXXXXXXXXXXXXGSPGQPNPMSPQQHMLSGQPQASHLPGQQIAT 2336
               ADSTPN                   GSPGQPNPMSPQQHMLSGQPQASHLPGQQIAT
Sbjct: 2278 GLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIAT 2337

Query: 2337 SLSNQVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGTPHPGLAVTMASSMDQ 2396
            SLSNQV                                    TG+PHPGLAVTMASS+DQ
Sbjct: 2338 SLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQ 2397

Query: 2397 GHLGNPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL 2441
            GHLGNPEQSAMLPQLNTP+RSALSSELSLVGDTTGDTLEKFVEGL
Sbjct: 2398 GHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL 2442



>gi|27666550|ref|XP_235770.1| similar to E1A-associated protein p300 [Rattus norvegicus]
          Length = 1605

 Score = 1126 bits (2912), Expect = 0.0
 Identities = 611/913 (66%), Positives = 670/913 (73%), Gaps = 96/913 (10%)

Query: 962  LSQAAASIDNRVPTPSTVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRSE 1021
            LSQ A S++ +V  P + +S E +SQ      P  E+K EV+ D  +PEP +++ +   E
Sbjct: 437  LSQPAVSVEGQVSNPPSTSSTEVNSQTIPEKQPSQEVKMEVKMDVDQPEPADAQPDDTKE 496

Query: 1022 MMEEDLQGSSQVKEETDTTEQKSXXXXXXXXXXXXXXXXXXXXXNSSNDTASQSTSPSQP 1081
               ED +      E T+T E+                         S   A  S +P Q 
Sbjct: 497  AKAEDGK-----VEPTETEER----------GPELKTEVKEEEDQPSTSAAQSSPAPGQS 541

Query: 1082 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR 1141
            +KKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK+PMDLSTIKR
Sbjct: 542  KKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKR 601

Query: 1142 KLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC 1201
            KLDTGQYQEPWQY+DD+ LMFNNAWLYNRKTSRVYK+CSKL+EVFEQEIDPVMQSLGYCC
Sbjct: 602  KLDTGQYQEPWQYIDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCC 661

Query: 1202 GRK------------YEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCGKCFTEIQGEN 1249
            GRK             EFSPQTLCCYGKQLCTIPRDA YYSYQNRYHFC KCF EIQGE+
Sbjct: 662  GRKVFALLNKYFLLQLEFSPQTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGES 721

Query: 1250 VTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVC 1309
            V+LGDDPSQPQTTI+K+QF K+KNDTLDPE FV+C ECGRKMHQICVLH+++IWPSGFVC
Sbjct: 722  VSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEVIWPSGFVC 781

Query: 1310 DNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKT 1369
            D CLKKT R RKENKFSAKRL +TRLG  LE+R                           
Sbjct: 782  DGCLKKTARTRKENKFSAKRLPSTRLGTFLENR--------------------------- 814

Query: 1370 VEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGC 1429
                                      ALFAFEEIDGVD+CFFGMHVQ+     P   Q  
Sbjct: 815  --------------------------ALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRR 848

Query: 1430 VYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHP 1489
            VYISYLDS+HFFRP+CLRTAVYHEILIGYLEYVKKL Y T HIWACPPSEGDDYIFHCHP
Sbjct: 849  VYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHP 908

Query: 1490 PDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNV 1549
            PDQKIPKPKRLQEWYKKMLDKA +ERI++DYKDI KQA EDRLTSAKELPYFEGDFWPNV
Sbjct: 909  PDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDILKQATEDRLTSAKELPYFEGDFWPNV 968

Query: 1550 LXXXXXXXXXXXXXXXXXXXXXXXXTPEGSQGDSXXXXXXXXXXXXXXXSSISRANKKKP 1609
            L                        T + ++GDS               SS+SR NKKKP
Sbjct: 969  LEESIKELEQEEEERKREENTSNEST-DVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKP 1027

Query: 1610 SMPNVSNDLSQKLYATMEKHKE---------------VFFVIHLHAGPVISTQPPIVDPD 1654
             +PNVSNDLSQKLYATMEKHKE               VFFVI L A P  ++ PPIVDPD
Sbjct: 1028 GVPNVSNDLSQKLYATMEKHKEWHYSSRVTVSLVCWQVFFVIRLIACPAPNSLPPIVDPD 1087

Query: 1655 PLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHH 1714
            PL+ CDLMDGRDAFLTLARDKH EFSSLRR++WST+CMLVELHTQ QDRFVYTCNECKHH
Sbjct: 1088 PLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHH 1147

Query: 1715 VETRWHCTVCEDYDLCINCYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQ 1774
            VETRWHCTVCEDYDLCI CYNTK+H HKM K GLGLDDE ++Q    ++SP +SRRLSIQ
Sbjct: 1148 VETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQ 1207

Query: 1775 RCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHC 1834
            RCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCP+CKQLIALCCYHAKHC
Sbjct: 1208 RCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHC 1267

Query: 1835 QENKCPVPFCLNI 1847
            QENKCPVPFCLNI
Sbjct: 1268 QENKCPVPFCLNI 1280




 Score =  353 bits (905), Expect = 3e-95
 Identities = 217/411 (52%), Positives = 259/411 (63%), Gaps = 37/411 (9%)

Query: 387 MKNVLNHMTHCQAPKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILG 446
           MKNVLNHMTHCQ+ K+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQQ+IL 
Sbjct: 1   MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQSILT 60

Query: 447 SPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSMQRAYAALGLPYM--NXXXXXXXXXXX 504
               G+ N   S+G GQQ+  SLS  + IDPSS++RAYAALGLPY               
Sbjct: 61  GAPVGLGNP-SSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQIPPQPPVQAKN 119

Query: 505 XXXXXXXXXXXXMRTLNALGNNPMSVPAGGITTDQQPPNLISESALPTSLGATNPLMNDG 564
                       MR++N +  +PM V  G      Q PNL+S+S L +++ + NP+MN+ 
Sbjct: 120 QQSQPSGQSPQGMRSMNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINSQNPMMNE- 175

Query: 565 SNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRR 624
             + ++ SL  +PTAA PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRR
Sbjct: 176 --NASVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRR 233

Query: 625 MENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPAL 684
           MENLVAYA+KVEGDMYESAN+R EYYHLLAEKIYKIQKELEEKRRTRL KQ +L + P +
Sbjct: 234 MENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPSAPGM 293

Query: 685 --------PASGAQPPVIPPAQ------SVRPPNGPLPLPVNRMQVSQGMNSFNPMSLGN 730
                   P  G QP  +          SV  P+GPLP P           S    S+ N
Sbjct: 294 VPVPMNTAPNMGQQPTGMTTKTKGYLTISVSTPDGPLPDP-----------SMIRGSVPN 342

Query: 731 VQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQP---PNMMGTH 778
             +P+    P +     H   +   A     +  PSR P P   P  +GT 
Sbjct: 343 QMMPRMTPQPGSQGSHIHCPTLPQQAHQNSPSPVPSRTPTPHHTPPSIGTQ 393




 Score = 49.3 bits (116), Expect = 9e-04
 Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 24/128 (18%)

Query: 1988 GMGTPGSQMTP--VGLNVPRPNQVSG----PVMSSMXXXXXXXXXXXXXXXXXXXXXXVM 2041
            GMG  G Q  P      +P+P Q+      P M S+                       +
Sbjct: 1453 GMGPAGMQQQPPWAQGGMPQPQQMQSGMPRPAMMSVAQHGQP-----------------L 1495

Query: 2042 SMQAQAAVAGPRMPNVQPNRSISPSALQDLLRTLKXXXXXXXXXXVLNILKSNPQLMAAF 2101
            +M  Q  +    +  ++P  ++S  ALQ+LLRTL+          VL+IL +NPQL+AAF
Sbjct: 1496 NMAPQPGLGQVGVSPLKPG-TVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAF 1554

Query: 2102 IKQRTAKY 2109
            IKQR AKY
Sbjct: 1555 IKQRAAKY 1562



>gi|31204369|ref|XP_311133.1| ENSANGP00000004748 [Anopheles gambiae]
 gi|30178093|gb|EAA06516.2| ENSANGP00000004748 [Anopheles gambiae str. PEST]
          Length = 2572

 Score = 1021 bits (2640), Expect = 0.0
 Identities = 522/796 (65%), Positives = 613/796 (77%), Gaps = 23/796 (2%)

Query: 1074 QSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNP 1133
            Q+ +    +K  FKPEELR+AL+PTLE L  Q+PES+PFR PVDP  LGIPDYFDIV+ P
Sbjct: 1415 QTNASDNKKKCSFKPEELREALLPTLEKLVTQEPESIPFRMPVDPNSLGIPDYFDIVRQP 1474

Query: 1134 MDLSTIKRKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPV 1193
            MDLSTI++KL++GQYQ+P +YVDDV LMF+NAWLYNRKTSRVY++C+KL+EVFE EIDPV
Sbjct: 1475 MDLSTIRKKLESGQYQDPREYVDDVWLMFDNAWLYNRKTSRVYRYCTKLSEVFEMEIDPV 1534

Query: 1194 MQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQN--------RYHFCGKCFTEI 1245
            MQSLGYCCGRKY F+PQ LCCYGKQLCTIPRDA YYSYQN        RY +C KCF EI
Sbjct: 1535 MQSLGYCCGRKYTFNPQVLCCYGKQLCTIPRDAKYYSYQNRSFGALSTRYTYCQKCFNEI 1594

Query: 1246 QGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPS 1305
             G+ VTLGDDP Q QT I KDQF++ KND L+ EPFVDC +CGRK HQICVL+ + IWP 
Sbjct: 1595 PGDTVTLGDDPMQSQTQIKKDQFKEMKNDHLELEPFVDCLDCGRKQHQICVLYLESIWPG 1654

Query: 1306 GFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVAS 1365
            GFVCD CLKK G+ RK+NKF+AKRL T++LG ++E RVN FL+++    AGEV +RVV+S
Sbjct: 1655 GFVCDACLKKKGQKRKDNKFNAKRLPTSKLGTYIETRVNNFLKKK-EAGAGEVHIRVVSS 1713

Query: 1366 SDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQD--TALIAP 1423
            SDK VEVKPGM+SRFV++GEM   FPYR KALFAFEE+DGVDVCFFGMHVQ+  +   AP
Sbjct: 1714 SDKMVEVKPGMRSRFVENGEMLPEFPYRAKALFAFEEVDGVDVCFFGMHVQEYGSECAAP 1773

Query: 1424 HQIQGCVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDY 1483
            +  +  VYI+YLDS+HFFRPR  RT+VYHEIL+GY++Y K+L Y  AHIWACPPSEGDDY
Sbjct: 1774 NTRR--VYIAYLDSVHFFRPRQYRTSVYHEILLGYMDYAKQLGYTMAHIWACPPSEGDDY 1831

Query: 1484 IFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEG 1543
            IFHCHPP+Q+IPKPKRLQEWYKKMLDK   ER I DYKDI KQA ED+L SA ELPYFEG
Sbjct: 1832 IFHCHPPEQRIPKPKRLQEWYKKMLDKGMVERTIQDYKDILKQAMEDKLQSASELPYFEG 1891

Query: 1544 DFWPNVLXXXXXXXXXXXXXXXXXXXXXXXXTP-------EGSQGDSXXXXXXXXXXXXX 1596
            DFWPNVL                                   +  D              
Sbjct: 1892 DFWPNVLEESIKELDQEEEEKRKQAEREEAANAMIMSNDDSDTVADGKKKGQKKAKKSNK 1951

Query: 1597 XXSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPL 1656
              ++  ++NKK  +   + NDLS K++ATMEKHKEVFFVI LH+    ++  PI DPDPL
Sbjct: 1952 SKAAQRKSNKK--TNEQIGNDLSAKIFATMEKHKEVFFVIRLHSAQSAASLAPIQDPDPL 2009

Query: 1657 LSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVE 1716
            ++CDLMDGRDAFLTLARDKH+EFSSLRR+++STLCML ELH QGQD+FVYTCN CK+HVE
Sbjct: 2010 INCDLMDGRDAFLTLARDKHFEFSSLRRAQFSTLCMLYELHNQGQDKFVYTCNNCKNHVE 2069

Query: 1717 TRWHCTVCEDYDLCINCYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRC 1776
            TR+HCTVC+D+DLCI C     H HKM K G  LDD GSS  + +  +PQE+R+ SIQRC
Sbjct: 2070 TRYHCTVCDDFDLCITCKEKVGHQHKMDKLGFDLDD-GSSPSDVKQTNPQEARKQSIQRC 2128

Query: 1777 IQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQE 1836
            IQSLVHACQCR+ANC LPSCQKMKRVVQHTK CKRKT+GGCP+CKQLIALCCYHAKHCQE
Sbjct: 2129 IQSLVHACQCRDANCRLPSCQKMKRVVQHTKHCKRKTHGGCPICKQLIALCCYHAKHCQE 2188

Query: 1837 NKCPVPFCLNIKHNVR 1852
             KC VPFC NIKH ++
Sbjct: 2189 AKCLVPFCPNIKHKLK 2204




 Score =  125 bits (313), Expect = 1e-26
 Identities = 84/156 (53%), Positives = 93/156 (59%), Gaps = 20/156 (12%)

Query: 517 MRTLNALGNNPMSVPAGGI-TTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGSLST 575
           M  +NA   + MS   GG   T        +        G TNP M              
Sbjct: 689 MPLMNATNTSTMSGGGGGGPNTSSFAAGSGAGGGGAGGTGGTNPSM-------------- 734

Query: 576 IPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKV 635
              A P   T   K WH  VT DLR+HLVHKLVQAIFP+PDP+A+ D+RM NLVAYAKKV
Sbjct: 735 --VAVPVQGT---KDWHHSVTPDLRNHLVHKLVQAIFPSPDPSAMFDKRMYNLVAYAKKV 789

Query: 636 EGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTR 671
           EGDMYE ANSR EYYHLLAEKIYKIQKELEEKR+ R
Sbjct: 790 EGDMYEMANSRSEYYHLLAEKIYKIQKELEEKRQKR 825




 Score =  118 bits (296), Expect = 1e-24
 Identities = 73/107 (68%), Positives = 76/107 (71%), Gaps = 3/107 (2%)

Query: 345 ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQ 404
           ADPEKRKLIQQQLVLLLHAHKCQRRE  N     CSL HCRTMK VL HM  C   K C 
Sbjct: 338 ADPEKRKLIQQQLVLLLHAHKCQRREAENPSGNICSLAHCRTMKEVLTHMQSCLLGKNCP 397

Query: 405 VAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASG 451
             HC+SSRQII+HWKNC R DCPVCLPL+   DK  QQ  L  PA G
Sbjct: 398 KTHCSSSRQIINHWKNCQRQDCPVCLPLQQHHDK--QQDTL-EPAKG 441




 Score = 41.6 bits (96), Expect = 0.17
 Identities = 32/105 (30%), Positives = 44/105 (41%), Gaps = 13/105 (12%)

Query: 1755 SSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNAN------CSLPSCQKMKRVVQHTKG 1808
            S  G P    P++ + +  Q  +    H CQ R A       CSL  C+ MK V+ H + 
Sbjct: 330  SPGGNPLLADPEKRKLIQQQLVLLLHAHKCQRREAENPSGNICSLAHCRTMKEVLTHMQS 389

Query: 1809 C---KRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHN 1850
            C   K      C   +Q+I     H K+CQ   CPV   L   H+
Sbjct: 390  CLLGKNCPKTHCSSSRQIIN----HWKNCQRQDCPVCLPLQQHHD 430



>gi|7511830|pir||T13828 CREB-binding protein homolog - fruit fly (Drosophila melanogaster)
 gi|1916930|gb|AAB53050.1| CREB-binding protein homolog [Drosophila melanogaster]
          Length = 3190

 Score = 1004 bits (2596), Expect = 0.0
 Identities = 517/785 (65%), Positives = 589/785 (75%), Gaps = 19/785 (2%)

Query: 1082 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR 1141
            +K  F PEELR AL+PTLE LYRQ+PES+PFR PVDPQ LGIPDYF+IVK PMDL TI+ 
Sbjct: 1693 KKCQFNPEELRTALLPTLEKLYRQEPESVPFRYPVDPQALGIPDYFEIVKKPMDLGTIRT 1752

Query: 1142 KLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC 1201
             +  G+Y +PW+YVDDV LMF+NAWLYN KTSRVY++C+KL+EVFE EIDPVMQ+LGYCC
Sbjct: 1753 NIQNGKYSDPWEYVDDVWLMFDNAWLYNPKTSRVYRYCTKLSEVFEAEIDPVMQALGYCC 1812

Query: 1202 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQ----------NRYHFCGKCFTEIQGENVT 1251
            GRKY F+PQ LCCYGKQLCTIPRDA YYSYQ          NRY +C KCF +IQG+ VT
Sbjct: 1813 GRKYTFNPQVLCCYGKQLCTIPRDAKYYSYQNSLKEYGVASNRYTYCQKCFNDIQGDTVT 1872

Query: 1252 LGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDN 1311
            LGDDP Q QT I KDQF++ KND L+ EPFV+C+ECGRK HQICVL  D IWP GFVCDN
Sbjct: 1873 LGDDPLQSQTQIKKDQFKEMKNDHLELEPFVNCQECGRKQHQICVLWLDSIWPGGFVCDN 1932

Query: 1312 CLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVE 1371
            CLKK    RKENKF+AKRL TT+LG ++E RVN FL+++    AGEV +RVV+SSDK VE
Sbjct: 1933 CLKKKNSKRKENKFNAKRLPTTKLGVYIETRVNNFLKKK-EAGAGEVHIRVVSSSDKCVE 1991

Query: 1372 VKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVY 1431
            VKPGM+ RFV+ GEM   FPYR KALFAFEE+DG+DVCFFGMHVQ+     P      VY
Sbjct: 1992 VKPGMRRRFVEQGEMMNEFPYRAKALFAFEEVDGIDVCFFGMHVQEYGSECPAPNTRRVY 2051

Query: 1432 ISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPD 1491
            I+YLDS+HFFRPR  RTAVYHEIL+GY++YVK+L Y  AHIWACPPSEGDDYIFHCHP D
Sbjct: 2052 IAYLDSVHFFRPRQYRTAVYHEILLGYMDYVKQLGYTMAHIWACPPSEGDDYIFHCHPTD 2111

Query: 1492 QKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLX 1551
            QKIPKPKRLQEWYKKMLDK   ERII DYKDI KQA ED+L SA ELPYFEGDFWPNVL 
Sbjct: 2112 QKIPKPKRLQEWYKKMLDKGMIERIIQDYKDILKQAMEDKLGSAAELPYFEGDFWPNVLE 2171

Query: 1552 XXXXXXXXXXXXXXXXXXXXXXXTP-------EGSQGDSXXXXXXXXXXXXXXXSSISRA 1604
                                            E                      +  R 
Sbjct: 2172 ESIKELDQEEEEKRKQAEAAEAAAAANLFSIEENEVSGDGKKKGQKKAKKSNKSKAAQRK 2231

Query: 1605 NKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDG 1664
            N KK +     NDLS K+YATMEKHKEVFFVI LH+    ++  PI DPDPLL+CDLMDG
Sbjct: 2232 NSKKSNEHQSGNDLSTKIYATMEKHKEVFFVIRLHSAQSAASLAPIQDPDPLLTCDLMDG 2291

Query: 1665 RDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVC 1724
            RDAFLTLARDKH+EFSSLRR+++STL ML ELH QGQD+FVYTCN CK  VETR+HCTVC
Sbjct: 2292 RDAFLTLARDKHFEFSSLRRAQFSTLSMLYELHNQGQDKFVYTCNHCKTAVETRYHCTVC 2351

Query: 1725 EDYDLCINCYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHAC 1784
            +D+DLCI C     H HKM K G  +DD GS+  + +  +PQE+R+ SIQRCIQSL HAC
Sbjct: 2352 DDFDLCIVCKEKVGHQHKMEKLGFDIDD-GSALADHKQANPQEARKQSIQRCIQSLAHAC 2410

Query: 1785 QCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFC 1844
            QCR+ANC LPSCQKMK VVQHTK CKRK NGGCP+CKQLIALCCYHAK+C+E KCPVPFC
Sbjct: 2411 QCRDANCRLPSCQKMKLVVQHTKNCKRKPNGGCPICKQLIALCCYHAKNCEEQKCPVPFC 2470

Query: 1845 LNIKH 1849
             NIKH
Sbjct: 2471 PNIKH 2475




 Score =  115 bits (287), Expect = 1e-23
 Identities = 72/116 (62%), Positives = 81/116 (69%), Gaps = 3/116 (2%)

Query: 556  ATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTP 615
            A NP  N G  +G  G  +   T  P  +    K W E VT DLR+HLVHKLVQAIFPT 
Sbjct: 911  AGNPNQNAGGVAGGAGGGNGGNTGPPGDN---EKDWRESVTADLRNHLVHKLVQAIFPTS 967

Query: 616  DPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTR 671
            DP  ++D+RM NLV+YA+KVE DMYE A SR EYYHLLAEKIYKIQKELEEKR  R
Sbjct: 968  DPTTMQDKRMHNLVSYAEKVEKDMYEMAKSRSEYYHLLAEKIYKIQKELEEKRLKR 1023




 Score = 78.2 bits (191), Expect = 2e-12
 Identities = 42/86 (48%), Positives = 58/86 (67%)

Query: 348 EKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAH 407
           ++++ IQQQL+LLLHAHKC RRE  N     C++ +C+ MK+VL HM  C+  K C + H
Sbjct: 510 DRKRQIQQQLMLLLHAHKCNRRENLNPNREVCNVNYCKAMKSVLAHMGTCKQSKDCTMQH 569

Query: 408 CASSRQIISHWKNCTRHDCPVCLPLK 433
           CASSRQI+ H+K C    C +C P +
Sbjct: 570 CASSRQILLHYKTCQNSGCVICYPFR 595




 Score = 40.0 bits (92), Expect = 0.50
 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 13/95 (13%)

Query: 338  AIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHC 397
            A+A    A+P++ +    Q  +   AH CQ R+ AN     C LP C+ MK V+ H  +C
Sbjct: 2382 ALADHKQANPQEARKQSIQRCIQSLAHACQCRD-AN-----CRLPSCQKMKLVVQHTKNC 2435

Query: 398  QAPKACQVAHCASSRQIIS----HWKNCTRHDCPV 428
            +         C   +Q+I+    H KNC    CPV
Sbjct: 2436 KRKPN---GGCPICKQLIALCCYHAKNCEEQKCPV 2467



>gi|24640865|ref|NP_524642.2| nejire CG15319-PB [Drosophila melanogaster]
 gi|22833041|gb|AAF46516.2| CG15319-PB [Drosophila melanogaster]
          Length = 3276

 Score =  995 bits (2573), Expect = 0.0
 Identities = 518/785 (65%), Positives = 590/785 (75%), Gaps = 19/785 (2%)

Query: 1082 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR 1141
            +K  F PEELR AL+PTLE LYRQ+PES+PFR PVDPQ LGIPDYF+IVK PMDL TI+ 
Sbjct: 1693 KKCQFNPEELRTALLPTLEKLYRQEPESVPFRYPVDPQALGIPDYFEIVKKPMDLGTIRT 1752

Query: 1142 KLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC 1201
             +  G+Y +PW+YVDDV LMF+NAWLYNRKTSRVY++C+KL+EVFE EIDPVMQ+LGYCC
Sbjct: 1753 NIQNGKYSDPWEYVDDVWLMFDNAWLYNRKTSRVYRYCTKLSEVFEAEIDPVMQALGYCC 1812

Query: 1202 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQ----------NRYHFCGKCFTEIQGENVT 1251
            GRKY F+PQ LCCYGKQLCTIPRDA YYSYQ          NRY +C KCF +IQG+ VT
Sbjct: 1813 GRKYTFNPQVLCCYGKQLCTIPRDAKYYSYQNSLKEYGVASNRYTYCQKCFNDIQGDTVT 1872

Query: 1252 LGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDN 1311
            LGDDP Q QT I KDQF++ KND L+ EPFV+C+ECGRK HQICVL  D IWP GFVCDN
Sbjct: 1873 LGDDPLQSQTQIKKDQFKEMKNDHLELEPFVNCQECGRKQHQICVLWLDSIWPGGFVCDN 1932

Query: 1312 CLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVE 1371
            CLKK    RKENKF+AKRL TT+LG ++E RVN FL+++    AGEV +RVV+SSDK VE
Sbjct: 1933 CLKKKNSKRKENKFNAKRLPTTKLGVYIETRVNNFLKKK-EAGAGEVHIRVVSSSDKCVE 1991

Query: 1372 VKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVY 1431
            VKPGM+ RFV+ GEM   FPYR KALFAFEE+DG+DVCFFGMHVQ+     P      VY
Sbjct: 1992 VKPGMRRRFVEQGEMMNEFPYRAKALFAFEEVDGIDVCFFGMHVQEYGSECPAPNTRRVY 2051

Query: 1432 ISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPD 1491
            I+YLDS+HFFRPR  RTAVYHEIL+GY++YVK+L Y  AHIWACPPSEGDDYIFHCHP D
Sbjct: 2052 IAYLDSVHFFRPRQYRTAVYHEILLGYMDYVKQLGYTMAHIWACPPSEGDDYIFHCHPTD 2111

Query: 1492 QKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLX 1551
            QKIPKPKRLQEWYKKMLDK   ERII DYKDI KQA ED+L SA ELPYFEGDFWPNVL 
Sbjct: 2112 QKIPKPKRLQEWYKKMLDKGMIERIIQDYKDILKQAMEDKLGSAAELPYFEGDFWPNVLE 2171

Query: 1552 XXXXXXXXXXXXXXXXXXXXXXXTP-------EGSQGDSXXXXXXXXXXXXXXXSSISRA 1604
                                            E                      +  R 
Sbjct: 2172 ESIKELDQEEEEKRKQAEAAEAAAAANLFSIEENEVSGDGKKKGQKKAKKSNKSKAAQRK 2231

Query: 1605 NKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDG 1664
            N KK +     NDLS K+YATMEKHKEVFFVI LH+    ++  PI DPDPLL+CDLMDG
Sbjct: 2232 NSKKSNEHQSGNDLSTKIYATMEKHKEVFFVIRLHSAQSAASLAPIQDPDPLLTCDLMDG 2291

Query: 1665 RDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVC 1724
            RDAFLTLARDKH+EFSSLRR+++STL ML ELH QGQD+FVYTCN CK  VETR+HCTVC
Sbjct: 2292 RDAFLTLARDKHFEFSSLRRAQFSTLSMLYELHNQGQDKFVYTCNHCKTAVETRYHCTVC 2351

Query: 1725 EDYDLCINCYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHAC 1784
            +D+DLCI C     H HKM K G  +DD GS+  + +  +PQE+R+ SIQRCIQSL HAC
Sbjct: 2352 DDFDLCIVCKEKVGHQHKMEKLGFDIDD-GSALADHKQANPQEARKQSIQRCIQSLAHAC 2410

Query: 1785 QCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFC 1844
            QCR+ANC LPSCQKMK VVQHTK CKRK NGGCP+CKQLIALCCYHAK+C+E KCPVPFC
Sbjct: 2411 QCRDANCRLPSCQKMKLVVQHTKNCKRKPNGGCPICKQLIALCCYHAKNCEEQKCPVPFC 2470

Query: 1845 LNIKH 1849
             NIKH
Sbjct: 2471 PNIKH 2475




 Score =  114 bits (284), Expect = 3e-23
 Identities = 72/116 (62%), Positives = 81/116 (69%), Gaps = 3/116 (2%)

Query: 556  ATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTP 615
            A NP  N G  +G  G  +   T  P  +    K W E VT DLR+HLVHKLVQAIFPT 
Sbjct: 911  AGNPNQNAGGVAGGAGGGNGGNTGPPGDN---EKDWRESVTADLRNHLVHKLVQAIFPTS 967

Query: 616  DPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTR 671
            DP  ++D+RM NLV+YA+KVE DMYE A SR EYYHLLAEKIYKIQKELEEKR  R
Sbjct: 968  DPTTMQDKRMHNLVSYAEKVEKDMYEMAKSRSEYYHLLAEKIYKIQKELEEKRLKR 1023




 Score = 77.4 bits (189), Expect = 3e-12
 Identities = 42/86 (48%), Positives = 58/86 (67%)

Query: 348 EKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAH 407
           ++++ IQQQL+LLLHAHKC RRE  N     C++ +C+ MK+VL HM  C+  K C + H
Sbjct: 510 DRKRQIQQQLMLLLHAHKCNRRENLNPNREVCNVNYCKAMKSVLAHMGTCKQSKDCTMQH 569

Query: 408 CASSRQIISHWKNCTRHDCPVCLPLK 433
           CASSRQI+ H+K C    C +C P +
Sbjct: 570 CASSRQILLHYKTCQNSGCVICYPFR 595




 Score = 39.7 bits (91), Expect = 0.81
 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 13/95 (13%)

Query: 338  AIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHC 397
            A+A    A+P++ +    Q  +   AH CQ R+ AN     C LP C+ MK V+ H  +C
Sbjct: 2382 ALADHKQANPQEARKQSIQRCIQSLAHACQCRD-AN-----CRLPSCQKMKLVVQHTKNC 2435

Query: 398  QAPKACQVAHCASSRQIIS----HWKNCTRHDCPV 428
            +         C   +Q+I+    H KNC    CPV
Sbjct: 2436 KRKPN---GGCPICKQLIALCCYHAKNCEEQKCPV 2467



>gi|1888540|gb|AAC51340.1| CREB-binding protein [Homo sapiens]
          Length = 932

 Score =  978 bits (2527), Expect = 0.0
 Identities = 597/929 (64%), Positives = 612/929 (65%), Gaps = 2/929 (0%)

Query: 1515 RIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLXXXXXXXXXXXXXXXXXXXXXXXX 1574
            RII+DYKDIFKQA EDRLTSAKELPYFEGDFWPNVL                        
Sbjct: 4    RIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASE 63

Query: 1575 TPEGSQGDSXXXXXXXXXXXXXXXSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFF 1634
            T EGSQGDS               SSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFF
Sbjct: 64   TTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFF 123

Query: 1635 VIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLV 1694
            VIHLHAGPVI+T PPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLV
Sbjct: 124  VIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLV 183

Query: 1695 ELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKWGLGLDDEG 1754
            ELHTQGQDRFVYTCNECKHHVETRWHCTVC  YDLCINCYNTKSH HKMVKWGLGLDDEG
Sbjct: 184  ELHTQGQDRFVYTCNECKHHVETRWHCTVCVVYDLCINCYNTKSHAHKMVKWGLGLDDEG 243

Query: 1755 SSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTN 1814
            SSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNA CSLPSCQKMKRVVQHTKGCKRK N
Sbjct: 244  SSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNAFCSLPSCQKMKRVVQHTKGCKRKPN 303

Query: 1815 GGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHNVRXXXXXXXXXXXXLXXXXXXXXX 1874
            GGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKH +R            L         
Sbjct: 304  GGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMN 363

Query: 1875 XXXVPQQSLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVNMSPAGFPNVARTQPPTIV 1934
               VPQQSL                               V+MSPAGFP+VARTQPPT V
Sbjct: 364  TRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTV 423

Query: 1935 SAGKPTNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHLYRANINNGMPPGRDGMGTPGS 1994
            S GKPT+                              HLYR NINN MPPGR GMGTPGS
Sbjct: 424  STGKPTSQVXAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGS 483

Query: 1995 QMTPVGLNVPRPNQVSGPVMSSMXXXXXXXXXXXXXXXXXXXXXXVMSMQAQAAVAGPRM 2054
            QM PV LNVPRPNQVSGPVM SM                      V+SMQAQAAVAGPRM
Sbjct: 484  QMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRM 543

Query: 2055 PNVQPNRSISPSALQDLLRTLKXXXXXXXXXXVLNILKSNPQLMAAFIKQRTAKYVANXX 2114
            P+VQP RSISPSALQDLLRTLK          VLNILKSNPQLMAAFIKQRTAKYVAN  
Sbjct: 544  PSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQP 603

Query: 2115 XXXXXXXXXXXXXXXXXXXXXXXXSLQNLNAMXXXXXXXXXXXXXXXMGGLNPQGQALNI 2174
                                    SLQNLNAM               MGGLNPQGQALNI
Sbjct: 604  GMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNI 663

Query: 2175 MNPGHNPNMTNMNPQYREMVRR-XXXXXXXXXXXXXXXXXXXXNSASLAGGMAGHSQFQQ 2233
            MNPGHNPNM +MNPQYREM+RR                      SA +AGGMAGH QFQQ
Sbjct: 664  MNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQ 723

Query: 2234 PQGPGGYAPA-MQQQRMQQHLPIQGSSXXXXXXXXXXXXXXXXXXXXADSTPNXXXXXXX 2292
            PQGPGGY PA  QQQRMQQHLP+QGSS                    ADSTPN       
Sbjct: 724  PQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQ 783

Query: 2293 XXXXXXXXXXXXGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVXXXXXXXXXX 2352
                        GSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQV          
Sbjct: 784  RILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPR 843

Query: 2353 XXXXXXXXXXXXXXXXXXXXXXXXXXTGTPHPGLAVTMASSMDQGHLGNPEQSAMLPQLN 2412
                                      TG+PHPGLAVTMASS+DQGHLGNPEQSAMLPQLN
Sbjct: 844  PQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLN 903

Query: 2413 TPNRSALSSELSLVGDTTGDTLEKFVEGL 2441
            TP+RSALSSELSLVGDTTGDTLEKFVEGL
Sbjct: 904  TPSRSALSSELSLVGDTTGDTLEKFVEGL 932



>gi|3168627|gb|AAC17736.1| CBP [Homo sapiens]
          Length = 923

 Score =  869 bits (2245), Expect = 0.0
 Identities = 529/843 (62%), Positives = 547/843 (64%), Gaps = 13/843 (1%)

Query: 1612 PNVSND-----------LSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCD 1660
            PNV  +             ++      +  EVFFVIHLHAGPVI+T PPIVDPDPLLSCD
Sbjct: 81   PNVLEESIKELEQEEEERKKEESTAASETTEVFFVIHLHAGPVINTLPPIVDPDPLLSCD 140

Query: 1661 LMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWH 1720
            LMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWH
Sbjct: 141  LMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWH 200

Query: 1721 CTVCEDYDLCINCYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSL 1780
            CTVCEDYDLCINCYNTKSH HKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSL
Sbjct: 201  CTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSL 260

Query: 1781 VHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCP 1840
            VHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCP
Sbjct: 261  VHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCP 320

Query: 1841 VPFCLNIKHNVRXXXXXXXXXXXXLXXXXXXXXXXXXVPQQSLXXXXXXXXXXXXXXXXX 1900
            VPFCLNIKH +R            L            VPQQSL                 
Sbjct: 321  VPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPST 380

Query: 1901 XXXXXXXXXXXXXXVNMSPAGFPNVARTQPPTIVSAGKPTNXXXXXXXXXXXXXXXXXXX 1960
                          V+MSPAGFP+VARTQPPT VS GKPT+                   
Sbjct: 381  PQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAA 440

Query: 1961 XXXXXXXXXXXHLYRANINNGMPPGRDGMGTPGSQMTPVGLNVPRPNQVSGPVMSSMXXX 2020
                       HLYR NINN MPPGR GMGTPGSQM PV LNVPRPNQVSGPVM SM   
Sbjct: 441  RQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPG 500

Query: 2021 XXXXXXXXXXXXXXXXXXXVMSMQAQAAVAGPRMPNVQPNRSISPSALQDLLRTLKXXXX 2080
                               V+SMQAQAAVAGPRMP+VQP RSISPSALQDLLRTLK    
Sbjct: 501  QWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSS 560

Query: 2081 XXXXXXVLNILKSNPQLMAAFIKQRTAKYVANXXXXXXXXXXXXXXXXXXXXXXXXXXSL 2140
                  VLNILKSNPQLMAAFIKQRTAKYVAN                          SL
Sbjct: 561  PQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSL 620

Query: 2141 QNLNAMXXXXXXXXXXXXXXXMGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRR-XXX 2199
            QNLNAM               MGGLNPQGQALNIMNPGHNPNM +MNPQYREM+RR    
Sbjct: 621  QNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQ 680

Query: 2200 XXXXXXXXXXXXXXXXXNSASLAGGMAGHSQFQQPQGPGGYAPA-MQQQRMQQHLPIQGS 2258
                              SA +AGGMAGH QFQQPQGPGGY PA  QQQRMQQHLP+QGS
Sbjct: 681  QQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGS 740

Query: 2259 SXXXXXXXXXXXXXXXXXXXXADSTPNXXXXXXXXXXXXXXXXXXXGSPGQPNPMSPQQH 2318
            S                    ADSTPN                   GSPGQPNPMSPQQH
Sbjct: 741  SMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQH 800

Query: 2319 MLSGQPQASHLPGQQIATSLSNQVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2378
            MLSGQPQASHLPGQQIATSLSNQV                                    
Sbjct: 801  MLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQ 860

Query: 2379 TGTPHPGLAVTMASSMDQGHLGNPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFV 2438
            TG+PHPGLAVTMASS+DQGHLGNPEQSAMLPQLNTP+RSALSSELSLVGDTTGDTLEKFV
Sbjct: 861  TGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFV 920

Query: 2439 EGL 2441
            EGL
Sbjct: 921  EGL 923




 Score =  164 bits (414), Expect = 3e-38
 Identities = 81/84 (96%), Positives = 82/84 (97%)

Query: 1467 YVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQ 1526
            YVT HIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERII+DYKDIFKQ
Sbjct: 1    YVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQ 60

Query: 1527 ANEDRLTSAKELPYFEGDFWPNVL 1550
            A EDRLTSAKELPYFEGDFWPNVL
Sbjct: 61   ATEDRLTSAKELPYFEGDFWPNVL 84



>gi|2996629|gb|AAC08447.1| CBP [Homo sapiens]
          Length = 555

 Score =  863 bits (2230), Expect = 0.0
 Identities = 501/551 (90%), Positives = 508/551 (92%), Gaps = 3/551 (0%)

Query: 273 SPFGQPFSQTGGQQMGATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVG 332
           SPFGQPFSQ GGQ MGATGVNPQLASKQSMVNSLP FPTDIKNTSVT VPNMSQ+QTSVG
Sbjct: 8   SPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVG 67

Query: 333 IVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLN 392
           IVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLN
Sbjct: 68  IVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLN 127

Query: 393 HMTHCQAPKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGI 452
           HMTHCQA KACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGI
Sbjct: 128 HMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGI 187

Query: 453 QNTIGSVGAGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNXXXXXXXXXXXXXXXXXXX 512
           QNTIGSVG GQQNATSLSNPNPIDPSSMQRAYAALGLPYMN                   
Sbjct: 188 QNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQ 247

Query: 513 XXXXMRTLNALGNNPMSVPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGS 572
               MRTLN LGNNPM++PAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIG+
Sbjct: 248 THQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGT 307

Query: 573 LSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYA 632
           LSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYA
Sbjct: 308 LSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYA 367

Query: 633 KKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPALPASGAQPP 692
           KKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRR+RLHKQGILGNQPALPA GAQPP
Sbjct: 368 KKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPP 427

Query: 693 VIPPAQSVRPPNGPLPLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQM 752
           VIP AQ VRPPNGPL LPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQM
Sbjct: 428 VIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQM 487

Query: 753 NSMASVPGMAISPSRMPQPPNMMGTHANNIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGM 812
           NSM SVPGMAISPSRMPQPPNMMG H NN+MAQAP Q+QFLPQNQFPSSSGAM   SVGM
Sbjct: 488 NSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAM---SVGM 544

Query: 813 GQPAAQAGVSQ 823
           GQP AQ GVSQ
Sbjct: 545 GQPPAQTGVSQ 555



>gi|27881767|gb|AAH44677.1| Similar to CREB binding protein (Rubinstein-Taybi syndrome) [Xenopus
            laevis]
          Length = 1047

 Score =  847 bits (2187), Expect = 0.0
 Identities = 580/1057 (54%), Positives = 684/1057 (64%), Gaps = 53/1057 (5%)

Query: 1    MAENLLDGPPNPKRAKLSSPGFSAN-DNTDFGSLFDLENDLPDELIPXXXXXXXXXXXXV 59
            MAENLLDGPPN KR KLSSPGFSA+ D+TDF S FDLENDLPDELIP             
Sbjct: 1    MAENLLDGPPNRKRPKLSSPGFSASTDSTDF-SFFDLENDLPDELIPNGGELSILGTGGS 59

Query: 60   --PDAASKHKQLSELLRXXXXXXXXXXXXXXXASSPVXXXXXXXXXXXPNSTNMASLGAM 117
               DAAS+++QLS+LLR               + SPV            +S  + +LG++
Sbjct: 60   LGQDAASQNRQLSDLLR-GGNAGLGAAMGRGRSGSPV--QQGLGSQGQQHSPGLGNLGSL 116

Query: 118  GKSPLNQGDSST-PNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICM 176
             KSPLNQG S T P    +   T GP+ PAS     QAQKQV +V  S A SQ   G+CM
Sbjct: 117  NKSPLNQGLSVTSPAGLTKTTGTPGPSVPAS-----QAQKQVSMVAGSTAPSQVPTGLCM 171

Query: 177  NANFNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLXXXXXXXXXXXXXXXXXXXXXTSS 236
            N+NFNQ H  LLNSNSGH+LM+QAQ  Q QV+NGSL                       S
Sbjct: 172  NSNFNQGHQTLLNSNSGHTLMSQAQPAQGQVLNGSLGVGSRGRGTALQYNSPAMQTNPGS 231

Query: 237  VLAETLTQVSPQMAGHAGLNTAQAXXXXXXXXXXXXSPFGQPFSQTGGQQMGATGVNPQL 296
            VLAETLTQ +  M  HAG+ TAQ             SPFGQ F+Q  GQQ+ A GV+PQL
Sbjct: 232  VLAETLTQGTATMPTHAGMTTAQTGAMNKMGLPGNTSPFGQTFNQAAGQQIRAQGVSPQL 291

Query: 297  ASKQSMVNSLPAFPTDIKNTSVTTVPNMSQLQT---SVGIVPTQAIATGPTADPEKRKLI 353
             +K +M NSLP FP+DIKN  V  +PNMS LQ     VGI  + ++ TGPTADPEKRKLI
Sbjct: 292  PAKPAMANSLPPFPSDIKNAPVANLPNMSPLQAQVQQVGIGTSPSMGTGPTADPEKRKLI 351

Query: 354  QQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQ 413
            QQQLVLLLHAHKCQRREQANGE+R CSLPHCRTMKNVLNHMTHCQA KACQVAHCASSRQ
Sbjct: 352  QQQLVLLLHAHKCQRREQANGEMRDCSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQ 411

Query: 414  IISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPN 473
            IISHWKNCTRHDCPVCLPLKNASDKRNQ   + S ASG+Q+ IG+ G GQQ A SLS+PN
Sbjct: 412  IISHWKNCTRHDCPVCLPLKNASDKRNQNLPV-SLASGVQSPIGTTGGGQQTAPSLSSPN 470

Query: 474  PIDPSSMQRAYAALGLPYMNXXXXXXXXXXXXXXXXXXXXXXXMRTLNALGNNPMSVPAG 533
            PIDPSSMQRAYAALGLPY N                       +R +NALG N M++ AG
Sbjct: 471  PIDPSSMQRAYAALGLPYGN------PAQGTGQQPAQTQVHQQIRNMNALGGNQMNLTAG 524

Query: 534  GITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHE 593
            G+T +QQ  NLIS++ALPT+L  +N L++DG+    +G+  T+PTAAPPSSTGVRK WHE
Sbjct: 525  GMTVEQQ-TNLISDTALPTALANSNSLLSDGNGQSTVGNHGTMPTAAPPSSTGVRKAWHE 583

Query: 594  HVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLL 653
            HVTQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGDMYESANSRDEYYH L
Sbjct: 584  HVTQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANSRDEYYHFL 643

Query: 654  AEKIYKIQKELEEKRRTRLHKQGILGNQPALPASGAQP-------PVIPPAQSVRPPNGP 706
            AEKIYKIQKELEEKRR+RL KQGI+ +Q  L A GAQP       P +   Q VRP NGP
Sbjct: 644  AEKIYKIQKELEEKRRSRLQKQGIMSSQAPLQAPGAQPTALTQTSPALGQTQPVRPTNGP 703

Query: 707  LPL---PVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAI 763
            + +   P+NRMQV+ GMN F+ M +GNVQ+P APMGPRAASP+NH  Q+N+M SVP MA+
Sbjct: 704  ISMSTVPMNRMQVASGMNQFSNMPIGNVQMPTAPMGPRAASPLNHPAQINNMGSVPAMAM 763

Query: 764  SPSRMPQPPNMMGTHANNIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVS- 822
            SPSRM QP  ++G HA +++    TQ+QFL QNQFP+S+G +   SVG+GQ  A A VS 
Sbjct: 764  SPSRMSQPQPIIGAHAGSMIGPTQTQSQFLQQNQFPASAGTI---SVGLGQTGAGAAVSQ 820

Query: 823  QGQEPGAALP--NPLNMLAPQASQLPCPPVTQSPLHPTPPPAS-TAAGMPSLQHXXXXXX 879
            QGQ P A+LP  N +NML PQ SQLP P ++QSPLH TPP  + +AA MP +QH      
Sbjct: 821  QGQAPSASLPISNSMNMLGPQTSQLPRPALSQSPLHQTPPSVTASAAVMPPVQHPAPAAM 880

Query: 880  XXXXXXXXXXXXXXV-SSGQTPTPTPGSVPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 938
                          + + GQTP PTPGSVP                              
Sbjct: 881  TPPQPTAPAQPSTPLPTPGQTPAPTPGSVP---NAMQSQSTPTVQAAAQTQLTPQPQTPV 937

Query: 939  XXXXXXXXXXXXXXXXXXXXGTPLSQAAASIDNRVPTPSTVTSAETSSQQPGPDVPMLEM 998
                                  P + AAAS+DN V TP++V S +    QP PD  M E+
Sbjct: 938  PVQSVPTPQPAQLQPTSVHAPAPGTPAAASVDNHVRTPASVASTD---NQPAPDHSMTEV 994

Query: 999  KTEVQTDDAEPEPTESKGEPRSEMMEEDLQGSSQVKE 1035
            K EV+    EPE  E++ EP++E+   +   S+Q KE
Sbjct: 995  KVEVKM--GEPEVCENQVEPKTEV---EPNASTQAKE 1026



>gi|17552708|ref|NP_499161.1| CBP/p300 homolog (cbp-1) [Caenorhabditis elegans]
 gi|14530537|emb|CAA82353.2| C. elegans CBP-1 protein (corresponding sequence R10E11.1a)
            [Caenorhabditis elegans]
          Length = 2045

 Score =  701 bits (1809), Expect = 0.0
 Identities = 382/796 (47%), Positives = 496/796 (62%), Gaps = 26/796 (3%)

Query: 1072 ASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK 1131
            A +  +P      +F  E+L + L+P  E L + + ++ PFR PVD +LL IPDY +I+K
Sbjct: 839  AKREPTPPPTEDTVFSQEDLIKFLLPVWEKLDKSE-DAAPFRVPVDAKLLNIPDYHEIIK 897

Query: 1132 NPMDLSTIKRKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEID 1191
             PMDL T+ +KL  GQYQ   Q+ DD+ LM +NAWLYNRK S+VYK+  KL+E+F  E+D
Sbjct: 898  RPMDLETVHKKLYAGQYQNAGQFCDDIWLMLDNAWLYNRKNSKVYKYGLKLSEMFVSEMD 957

Query: 1192 PVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQN-----------RYHFCGK 1240
            PVM+S+GYCC +K  F+P +L CYG  +CTI R+  Y+ ++            RY +C K
Sbjct: 958  PVMKSMGYCCAKKLAFTPLSLFCYGAAMCTIAREQQYWVFEQSSTQYNVTVTERYTYCQK 1017

Query: 1241 CFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYD 1300
            CF  +  E ++L ++P+       K  F ++KN  +D EPF  CK C RK H+IC LH  
Sbjct: 1018 CFDALPPEGISLSENPNDRNNMAPKTSFTEQKNSVIDYEPFERCKYCMRKWHRICALHDK 1077

Query: 1301 IIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGE--V 1358
             ++P GF+C+ C       + +NK+ A +L   +L   LEDRVN F+++Q   EA +  V
Sbjct: 1078 KVYPEGFICECCRTAKKYQKPDNKYLASKLPHNKLSTFLEDRVNGFIKKQLQAEAHKYPV 1137

Query: 1359 FVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDT 1418
             +R +   DK  EVK  MK ++V+S +  E FPYRTKA+FAFE IDGV+VCFFG+HVQ+ 
Sbjct: 1138 IIRTLCVQDKEAEVKAQMKQKYVESNQFPEKFPYRTKAVFAFEIIDGVEVCFFGLHVQEY 1197

Query: 1419 ALIAPHQIQGCVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPS 1478
                P      VYI+YLDS+HFF+PR LRT VYHE+L+GYL+Y K L Y  AHIWACPPS
Sbjct: 1198 GSACPAPNARRVYIAYLDSVHFFQPRELRTDVYHELLLGYLDYAKMLGYTMAHIWACPPS 1257

Query: 1479 EGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKEL 1538
            EGDDYIFHCHPP+QKIPKPKRLQ+WYKKML+K   E  + ++KDI+KQA +D LT+  +L
Sbjct: 1258 EGDDYIFHCHPPEQKIPKPKRLQDWYKKMLEKGVQEGSVVEFKDIYKQARDDNLTTPTQL 1317

Query: 1539 PYFEGDFWPNVLXXXXXXXXXXXXXXXXXXXXXXXXTPEGSQGDSXXXXXXXXXXXXXXX 1598
            PYFEGDFWPNV+                          +G  G                 
Sbjct: 1318 PYFEGDFWPNVIEDCIREASNEEAQRKVKEDDDDGEDADGGLGGGDSGKKKSSKNKKNNL 1377

Query: 1599 SSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIH---LHAGPVISTQPPIVDPDP 1655
               ++ NKKK       N+++ KLY+  EKHKEVFF I    L   P +  + PI DPD 
Sbjct: 1378 KKNAKMNKKKAG-SITGNEVADKLYSQFEKHKEVFFTIRLVSLQNEPAVLAK-PISDPDG 1435

Query: 1656 LLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHV 1715
            L+  D+MDGRD FLT AR++HWEFSSLRR+K+STLC+   LH        YTCN+C    
Sbjct: 1436 LMQSDMMDGRDTFLTKAREEHWEFSSLRRAKYSTLCLAYSLHETDSKGMEYTCNKCSS-- 1493

Query: 1716 ETRWHCTVCEDYDLCINCYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQR 1775
               WHC  C+D+DLC  C  T  H H+M K    +       GE    +   +R  SIQR
Sbjct: 1494 PAVWHCQSCDDFDLCDGCKPTTQHPHEMEKIKSLI-----GGGEAGDSAAGGTRYESIQR 1548

Query: 1776 CIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQ 1835
            CI SLVHACQCR+ANC   SC KMKRVVQHTK CK++ NG CPVCKQLIALCCYHAKHC 
Sbjct: 1549 CIASLVHACQCRDANCRRMSCHKMKRVVQHTKMCKKRINGTCPVCKQLIALCCYHAKHCT 1608

Query: 1836 ENKCPVPFCLNIKHNV 1851
             + C VPFC+NI+  +
Sbjct: 1609 RDACTVPFCMNIRQKL 1624




 Score =  124 bits (310), Expect = 3e-26
 Identities = 103/314 (32%), Positives = 149/314 (47%), Gaps = 35/314 (11%)

Query: 558 NPLMNDGSNSGNIGSLST--IPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTP 615
           NP  N  +  G         IP   PP      K WH  VT+DLR+HLV KLV+AIFP P
Sbjct: 552 NPFQNGPNRGGPRPPGGNGEIPNLPPPDMPDCTKEWHHQVTKDLRNHLVGKLVKAIFPEP 611

Query: 616 DPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQ 675
           +  A+ D R+++L+AYA+KVE +M+ESAN R+EYYHLLAEKIYKIQKEL+EK+ +RL++ 
Sbjct: 612 NQEAMNDNRLKDLIAYARKVEKEMFESANDREEYYHLLAEKIYKIQKELQEKKNSRLNQG 671

Query: 676 GILGNQPALPASG--AQPPVIPPAQSVRPPNGP----LPLPVNRMQVSQGMNSFNPMSLG 729
               +Q A+P S   AQ   +   +S     G      P   N+       ++ +     
Sbjct: 672 AAAHDQYAIPPSNELAQMLGVEGGRSDVHSEGSSMAVAPSQQNQPWGGAPNSNMHQQIPP 731

Query: 730 NVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMP-----------QPPNMMGTH 778
           N Q+PQ        S  N +  + + ++V  M + P   P           +PP  +G  
Sbjct: 732 NGQVPQVNNSSTFPSSGNSTPNIGASSTVSAM-LQPKTEPMDDQNTDSLSSRPPTAIGFG 790

Query: 779 ANNIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQEPGAALPNPLNML 838
            ++    AP  N  + + + P  S   +  SV            +  + G A   P    
Sbjct: 791 GSSSSTPAPIMNGIVKKEEDPEESSNQAPPSV------------KDTKDGVAESKPKEQ- 837

Query: 839 APQASQLPCPPVTQ 852
             QA + P PP T+
Sbjct: 838 --QAKREPTPPPTE 849




 Score = 97.8 bits (242), Expect = 2e-18
 Identities = 83/202 (41%), Positives = 100/202 (49%), Gaps = 20/202 (9%)

Query: 274 PFGQPFSQTGGQQMGATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGI 333
           P GQP          A        ++              +  +     N +   T+ G 
Sbjct: 333 PNGQP-GPQAAAAQHAAQQQAAAQAQAQAAAQQQQQQQREQEAAAAAQRNGAGRATTPG- 390

Query: 334 VPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEV---------RACSLPHC 384
             +  +AT    DPEKRKLIQQQLVLLLHAHKC +RE+ N +           AC+LPHC
Sbjct: 391 --SSMLAT--HQDPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHC 446

Query: 385 RTMKNVLNHMTHCQAPKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTI 444
            TMK VL HMT C   + C  AHCASSRQII+HWKNC+R DCPVC PL     KR Q T 
Sbjct: 447 STMKEVLTHMTSCNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCKPL-----KRIQDTP 501

Query: 445 LGSPASGIQNTIGSVGAGQQNA 466
           L      + N IG  G    +A
Sbjct: 502 LQFSLPDLANLIGVNGNSNGSA 523



>gi|17552710|ref|NP_499160.1| CBP/p300 homolog (cbp-1) [Caenorhabditis elegans]
 gi|20455476|sp|P34545|CBP1_CAEEL Protein cbp-1
 gi|25299632|pir||G88564 protein R10E11.1 [imported] - Caenorhabditis elegans
 gi|17645979|emb|CAD18875.1| C. elegans CBP-1 protein (corresponding sequence R10E11.1b)
            [Caenorhabditis elegans]
          Length = 2056

 Score =  701 bits (1808), Expect = 0.0
 Identities = 382/796 (47%), Positives = 496/796 (62%), Gaps = 26/796 (3%)

Query: 1072 ASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK 1131
            A +  +P      +F  E+L + L+P  E L + + ++ PFR PVD +LL IPDY +I+K
Sbjct: 850  AKREPTPPPTEDTVFSQEDLIKFLLPVWEKLDKSE-DAAPFRVPVDAKLLNIPDYHEIIK 908

Query: 1132 NPMDLSTIKRKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEID 1191
             PMDL T+ +KL  GQYQ   Q+ DD+ LM +NAWLYNRK S+VYK+  KL+E+F  E+D
Sbjct: 909  RPMDLETVHKKLYAGQYQNAGQFCDDIWLMLDNAWLYNRKNSKVYKYGLKLSEMFVSEMD 968

Query: 1192 PVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQN-----------RYHFCGK 1240
            PVM+S+GYCC +K  F+P +L CYG  +CTI R+  Y+ ++            RY +C K
Sbjct: 969  PVMKSMGYCCAKKLAFTPLSLFCYGAAMCTIAREQQYWVFEQSSTQYNVTVTERYTYCQK 1028

Query: 1241 CFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYD 1300
            CF  +  E ++L ++P+       K  F ++KN  +D EPF  CK C RK H+IC LH  
Sbjct: 1029 CFDALPPEGISLSENPNDRNNMAPKTSFTEQKNSVIDYEPFERCKYCMRKWHRICALHDK 1088

Query: 1301 IIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGE--V 1358
             ++P GF+C+ C       + +NK+ A +L   +L   LEDRVN F+++Q   EA +  V
Sbjct: 1089 KVYPEGFICECCRTAKKYQKPDNKYLASKLPHNKLSTFLEDRVNGFIKKQLQAEAHKYPV 1148

Query: 1359 FVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDT 1418
             +R +   DK  EVK  MK ++V+S +  E FPYRTKA+FAFE IDGV+VCFFG+HVQ+ 
Sbjct: 1149 IIRTLCVQDKEAEVKAQMKQKYVESNQFPEKFPYRTKAVFAFEIIDGVEVCFFGLHVQEY 1208

Query: 1419 ALIAPHQIQGCVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPS 1478
                P      VYI+YLDS+HFF+PR LRT VYHE+L+GYL+Y K L Y  AHIWACPPS
Sbjct: 1209 GSACPAPNARRVYIAYLDSVHFFQPRELRTDVYHELLLGYLDYAKMLGYTMAHIWACPPS 1268

Query: 1479 EGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKEL 1538
            EGDDYIFHCHPP+QKIPKPKRLQ+WYKKML+K   E  + ++KDI+KQA +D LT+  +L
Sbjct: 1269 EGDDYIFHCHPPEQKIPKPKRLQDWYKKMLEKGVQEGSVVEFKDIYKQARDDNLTTPTQL 1328

Query: 1539 PYFEGDFWPNVLXXXXXXXXXXXXXXXXXXXXXXXXTPEGSQGDSXXXXXXXXXXXXXXX 1598
            PYFEGDFWPNV+                          +G  G                 
Sbjct: 1329 PYFEGDFWPNVIEDCIREASNEEAQRKVKEDDDDGEDADGGLGGGDSGKKKSSKNKKNNL 1388

Query: 1599 SSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIH---LHAGPVISTQPPIVDPDP 1655
               ++ NKKK       N+++ KLY+  EKHKEVFF I    L   P +  + PI DPD 
Sbjct: 1389 KKNAKMNKKKAG-SITGNEVADKLYSQFEKHKEVFFTIRLVSLQNEPAVLAK-PISDPDG 1446

Query: 1656 LLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHV 1715
            L+  D+MDGRD FLT AR++HWEFSSLRR+K+STLC+   LH        YTCN+C    
Sbjct: 1447 LMQSDMMDGRDTFLTKAREEHWEFSSLRRAKYSTLCLAYSLHETDSKGMEYTCNKCSS-- 1504

Query: 1716 ETRWHCTVCEDYDLCINCYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQR 1775
               WHC  C+D+DLC  C  T  H H+M K    +       GE    +   +R  SIQR
Sbjct: 1505 PAVWHCQSCDDFDLCDGCKPTTQHPHEMEKIKSLI-----GGGEAGDSAAGGTRYESIQR 1559

Query: 1776 CIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQ 1835
            CI SLVHACQCR+ANC   SC KMKRVVQHTK CK++ NG CPVCKQLIALCCYHAKHC 
Sbjct: 1560 CIASLVHACQCRDANCRRMSCHKMKRVVQHTKMCKKRINGTCPVCKQLIALCCYHAKHCT 1619

Query: 1836 ENKCPVPFCLNIKHNV 1851
             + C VPFC+NI+  +
Sbjct: 1620 RDACTVPFCMNIRQKL 1635




 Score =  123 bits (309), Expect = 3e-26
 Identities = 103/314 (32%), Positives = 149/314 (47%), Gaps = 35/314 (11%)

Query: 558 NPLMNDGSNSGNIGSLST--IPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTP 615
           NP  N  +  G         IP   PP      K WH  VT+DLR+HLV KLV+AIFP P
Sbjct: 563 NPFQNGPNRGGPRPPGGNGEIPNLPPPDMPDCTKEWHHQVTKDLRNHLVGKLVKAIFPEP 622

Query: 616 DPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQ 675
           +  A+ D R+++L+AYA+KVE +M+ESAN R+EYYHLLAEKIYKIQKEL+EK+ +RL++ 
Sbjct: 623 NQEAMNDNRLKDLIAYARKVEKEMFESANDREEYYHLLAEKIYKIQKELQEKKNSRLNQG 682

Query: 676 GILGNQPALPASG--AQPPVIPPAQSVRPPNGP----LPLPVNRMQVSQGMNSFNPMSLG 729
               +Q A+P S   AQ   +   +S     G      P   N+       ++ +     
Sbjct: 683 AAAHDQYAIPPSNELAQMLGVEGGRSDVHSEGSSMAVAPSQQNQPWGGAPNSNMHQQIPP 742

Query: 730 NVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMP-----------QPPNMMGTH 778
           N Q+PQ        S  N +  + + ++V  M + P   P           +PP  +G  
Sbjct: 743 NGQVPQVNNSSTFPSSGNSTPNIGASSTVSAM-LQPKTEPMDDQNTDSLSSRPPTAIGFG 801

Query: 779 ANNIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQEPGAALPNPLNML 838
            ++    AP  N  + + + P  S   +  SV            +  + G A   P    
Sbjct: 802 GSSSSTPAPIMNGIVKKEEDPEESSNQAPPSV------------KDTKDGVAESKPKEQ- 848

Query: 839 APQASQLPCPPVTQ 852
             QA + P PP T+
Sbjct: 849 --QAKREPTPPPTE 860




 Score = 94.7 bits (234), Expect = 2e-17
 Identities = 86/213 (40%), Positives = 102/213 (47%), Gaps = 31/213 (14%)

Query: 274 PFGQPFSQTGGQQMGATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGI 333
           P GQP          A        ++              +  +     N +   T+ G 
Sbjct: 333 PNGQP-GPQAAAAQHAAQQQAAAQAQAQAAAQQQQQQQREQEAAAAAQRNGAGRATTPG- 390

Query: 334 VPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEV---------RACSLPHC 384
             +  +AT    DPEKRKLIQQQLVLLLHAHKC +RE+ N +           AC+LPHC
Sbjct: 391 --SSMLAT--HQDPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHC 446

Query: 385 RTMKNVLNHMTHC-----------QAPKACQVAHCASSRQIISHWKNCTRHDCPVCLPLK 433
            TMK VL HMT C           Q  K C VAHCASSRQII+HWKNC+R DCPVC PL 
Sbjct: 447 STMKEVLTHMTSCNVGRLCHSDTTQTTKKCSVAHCASSRQIIAHWKNCSREDCPVCKPL- 505

Query: 434 NASDKRNQQTILGSPASGIQNTIGSVGAGQQNA 466
               KR Q T L      + N IG  G    +A
Sbjct: 506 ----KRIQDTPLQFSLPDLANLIGVNGNSNGSA 534



>gi|2133462|pir||S60123 hypothetical protein R10E11.1 - Caenorhabditis elegans
          Length = 2027

 Score =  700 bits (1807), Expect = 0.0
 Identities = 382/796 (47%), Positives = 496/796 (62%), Gaps = 26/796 (3%)

Query: 1072 ASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK 1131
            A +  +P      +F  E+L + L+P  E L + + ++ PFR PVD +LL IPDY +I+K
Sbjct: 850  AKREPTPPPTEDTVFSQEDLIKFLLPVWEKLDKSE-DAAPFRVPVDAKLLNIPDYHEIIK 908

Query: 1132 NPMDLSTIKRKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEID 1191
             PMDL T+ +KL  GQYQ   Q+ DD+ LM +NAWLYNRK S+VYK+  KL+E+F  E+D
Sbjct: 909  RPMDLETVHKKLYAGQYQNAGQFCDDIWLMLDNAWLYNRKNSKVYKYGLKLSEMFVSEMD 968

Query: 1192 PVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQN-----------RYHFCGK 1240
            PVM+S+GYCC +K  F+P +L CYG  +CTI R+  Y+ ++            RY +C K
Sbjct: 969  PVMKSMGYCCAKKLAFTPLSLFCYGAAMCTIAREQQYWVFEQSSTQYNVTVTERYTYCQK 1028

Query: 1241 CFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYD 1300
            CF  +  E ++L ++P+       K  F ++KN  +D EPF  CK C RK H+IC LH  
Sbjct: 1029 CFDALPPEGISLSENPNDRNNMAPKTSFTEQKNSVIDYEPFERCKYCMRKWHRICALHDK 1088

Query: 1301 IIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGE--V 1358
             ++P GF+C+ C       + +NK+ A +L   +L   LEDRVN F+++Q   EA +  V
Sbjct: 1089 KVYPEGFICECCRTAKKYQKPDNKYLASKLPHNKLSTFLEDRVNGFIKKQLQAEAHKYPV 1148

Query: 1359 FVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDT 1418
             +R +   DK  EVK  MK ++V+S +  E FPYRTKA+FAFE IDGV+VCFFG+HVQ+ 
Sbjct: 1149 IIRTLCVQDKEAEVKAQMKQKYVESNQFPEKFPYRTKAVFAFEIIDGVEVCFFGLHVQEY 1208

Query: 1419 ALIAPHQIQGCVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPS 1478
                P      VYI+YLDS+HFF+PR LRT VYHE+L+GYL+Y K L Y  AHIWACPPS
Sbjct: 1209 GSACPAPNARRVYIAYLDSVHFFQPRELRTDVYHELLLGYLDYAKMLGYTMAHIWACPPS 1268

Query: 1479 EGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKEL 1538
            EGDDYIFHCHPP+QKIPKPKRLQ+WYKKML+K   E  + ++KDI+KQA +D LT+  +L
Sbjct: 1269 EGDDYIFHCHPPEQKIPKPKRLQDWYKKMLEKGVQEGSVVEFKDIYKQARDDNLTTPTQL 1328

Query: 1539 PYFEGDFWPNVLXXXXXXXXXXXXXXXXXXXXXXXXTPEGSQGDSXXXXXXXXXXXXXXX 1598
            PYFEGDFWPNV+                          +G  G                 
Sbjct: 1329 PYFEGDFWPNVIEDCIREASNEEAQRKVKEDDDDGEDADGGLGGGDSGKKKSSKNKKNNL 1388

Query: 1599 SSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIH---LHAGPVISTQPPIVDPDP 1655
               ++ NKKK       N+++ KLY+  EKHKEVFF I    L   P +  + PI DPD 
Sbjct: 1389 KKNAKMNKKKAG-SITGNEVADKLYSQFEKHKEVFFTIRLVSLQNEPAVLAK-PISDPDG 1446

Query: 1656 LLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHV 1715
            L+  D+MDGRD FLT AR++HWEFSSLRR+K+STLC+   LH        YTCN+C    
Sbjct: 1447 LMQSDMMDGRDTFLTKAREEHWEFSSLRRAKYSTLCLAYSLHETDSKGMEYTCNKCSS-- 1504

Query: 1716 ETRWHCTVCEDYDLCINCYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQR 1775
               WHC  C+D+DLC  C  T  H H+M K    +       GE    +   +R  SIQR
Sbjct: 1505 PAVWHCQSCDDFDLCDGCKPTTQHPHEMEKIKSLI-----GGGEAGDSAAGGTRYESIQR 1559

Query: 1776 CIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQ 1835
            CI SLVHACQCR+ANC   SC KMKRVVQHTK CK++ NG CPVCKQLIALCCYHAKHC 
Sbjct: 1560 CIASLVHACQCRDANCRRMSCHKMKRVVQHTKMCKKRINGTCPVCKQLIALCCYHAKHCT 1619

Query: 1836 ENKCPVPFCLNIKHNV 1851
             + C VPFC+NI+  +
Sbjct: 1620 RDACTVPFCMNIRQKL 1635




 Score =  123 bits (309), Expect = 4e-26
 Identities = 103/314 (32%), Positives = 149/314 (47%), Gaps = 35/314 (11%)

Query: 558 NPLMNDGSNSGNIGSLST--IPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTP 615
           NP  N  +  G         IP   PP      K WH  VT+DLR+HLV KLV+AIFP P
Sbjct: 563 NPFQNGPNRGGPRPPGGNGEIPNLPPPDMPDCTKEWHHQVTKDLRNHLVGKLVKAIFPEP 622

Query: 616 DPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQ 675
           +  A+ D R+++L+AYA+KVE +M+ESAN R+EYYHLLAEKIYKIQKEL+EK+ +RL++ 
Sbjct: 623 NQEAMNDNRLKDLIAYARKVEKEMFESANDREEYYHLLAEKIYKIQKELQEKKNSRLNQG 682

Query: 676 GILGNQPALPASG--AQPPVIPPAQSVRPPNGP----LPLPVNRMQVSQGMNSFNPMSLG 729
               +Q A+P S   AQ   +   +S     G      P   N+       ++ +     
Sbjct: 683 AAAHDQYAIPPSNELAQMLGVEGGRSDVHSEGSSMAVAPSQQNQPWGGAPNSNMHQQIPP 742

Query: 730 NVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMP-----------QPPNMMGTH 778
           N Q+PQ        S  N +  + + ++V  M + P   P           +PP  +G  
Sbjct: 743 NGQVPQVNNSSTFPSSGNSTPNIGASSTVSAM-LQPKTEPMDDQNTDSLSSRPPTAIGFG 801

Query: 779 ANNIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQEPGAALPNPLNML 838
            ++    AP  N  + + + P  S   +  SV            +  + G A   P    
Sbjct: 802 GSSSSTPAPIMNGIVKKEEDPEESSNQAPPSV------------KDTKDGVAESKPKEQ- 848

Query: 839 APQASQLPCPPVTQ 852
             QA + P PP T+
Sbjct: 849 --QAKREPTPPPTE 860




 Score = 94.0 bits (232), Expect = 3e-17
 Identities = 88/221 (39%), Positives = 98/221 (44%), Gaps = 47/221 (21%)

Query: 274 PFGQP--------FSQTGGQQMGATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMS 325
           P GQP         +        A         +Q       A           T P  S
Sbjct: 333 PNGQPGPQAAAAQHAAQQQAAAQAQAQAAAQQQQQQQREQEAAAAAQRNGAGRATTPGSS 392

Query: 326 QLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEV--------- 376
            L T                DPEKRKLIQQQLVLLLHAHKC +RE+ N +          
Sbjct: 393 MLATH--------------QDPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPH 438

Query: 377 RACSLPHCRTMKNVLNHMTHC-----------QAPKACQVAHCASSRQIISHWKNCTRHD 425
            AC+LPHC TMK VL HMT C           Q  K C VAHCASSRQII+HWKNC+R D
Sbjct: 439 AACTLPHCSTMKEVLTHMTSCNVGRLCHSDTTQTTKKCSVAHCASSRQIIAHWKNCSRED 498

Query: 426 CPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNA 466
           CPVC PL     KR Q T L      + N IG  G    +A
Sbjct: 499 CPVCKPL-----KRIQDTPLQFSLPDLANLIGVNGNSNGSA 534



>gi|31753089|gb|AAH53889.1| Unknown (protein for IMAGE:6151364) [Homo sapiens]
          Length = 1553

 Score =  541 bits (1393), Expect = e-152
 Identities = 402/903 (44%), Positives = 498/903 (55%), Gaps = 103/903 (11%)

Query: 1   MAENLLD-GPPNPKRAK--LSSPGFSANDNTDFGSLFDLENDLPDELIP---------XX 48
           MAEN+++ GPP+ KR K    +   SA+D TDFGSLFDLE+DLPDELI            
Sbjct: 1   MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60

Query: 49  XXXXXXXXXXVPDAASKHKQLSELLRXXXXXXXXXXXXXXXASSPVXXXXXXXXXXXPNS 108
                     V DAASKHKQLSELLR                                +S
Sbjct: 61  INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQ--------VMASQAQQSS 112

Query: 109 TNMASLGAMGKSPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATS 168
             +  + +M KSP+ Q   ++PN+      TSGP    +Q+         G++ S     
Sbjct: 113 PGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQP 161

Query: 169 QTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLXXXXXXXXXXXXXXXX 228
             G    MNA  N   PG+L + +G  +M        QVMNGS+                
Sbjct: 162 AMGMNTGMNAGMN---PGMLAAGNGQGIMPN------QVMNGSI---GAGRGRQNMQYPN 209

Query: 229 XXXXXTSSVLAETLTQVSPQMAGHAGLNTAQAXXXXXXXXXXXXSPFGQPFSQTGGQQMG 288
                  ++L E L Q SPQM G  GL   Q             +P+G P++Q  GQQ+G
Sbjct: 210 PGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQIG 266

Query: 289 ATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMS----QLQTSVGIVPTQAIATGP- 343
           A+G+  Q+ +K  + N+L  F  D K      +PNM           G+V   A   G  
Sbjct: 267 ASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGMGSG 326

Query: 344 --TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPK 401
             TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+ K
Sbjct: 327 AHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGK 386

Query: 402 ACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGA 461
           +CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQQ IL     G+ N   S+G 
Sbjct: 387 SCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNP-SSLGV 445

Query: 462 GQQNATSLSNPNPIDPSSMQRAYAALGLPYM--NXXXXXXXXXXXXXXXXXXXXXXXMRT 519
           GQQ+A +LS  + IDPSS++RAYAALGLPY                           MR 
Sbjct: 446 GQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGMRP 505

Query: 520 LNALGNNPMSVPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTA 579
           ++ +  +PM V  G      Q P+L+S+S L +++ + NP+M   S + ++ SL  +PTA
Sbjct: 506 MSNMSASPMGVNGG---VGVQTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMPTA 559

Query: 580 APPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDM 639
           A PS+TG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGDM
Sbjct: 560 AQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDM 619

Query: 640 YESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPAL-PASGAQPPVIPPAQ 698
           YESAN+R EYYHLLAEKIYKIQKELEEKRRTRL KQ +L N   + P S    P +   Q
Sbjct: 620 YESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQ 679

Query: 699 SVRPPNGPLPLP-----------VNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMN 747
                NGPLP P           + R+    G+N F  MS+      Q P+ PR   P+ 
Sbjct: 680 PGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMA-----QPPIVPRQTPPLQ 734

Query: 748 HSVQMNSMASV-PGMAISPSRMPQPPNMMGTHANNIMAQAPTQNQFLPQNQFPSSSGAMS 806
           H  Q+    ++ P M   P RM QP N               Q QFLPQ QFPS    M+
Sbjct: 735 HHGQLAQPGALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQ--GMN 776

Query: 807 VNSVGMGQPAAQAGVSQGQEPGAALP--NPLNMLAPQASQLPCPPVTQSPLH---PTPPP 861
           V ++ +   + QA VSQ Q   ++ P  +P+     Q S + CP + Q  LH   P+P P
Sbjct: 777 VTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVP 836

Query: 862 AST 864
           + T
Sbjct: 837 SRT 839



>gi|4557557|ref|NP_001420.1| E1A binding protein p300; E1A-binding protein, 300kD [Homo sapiens]
 gi|3024341|sp|Q09472|P300_HUMAN E1A-associated protein p300
 gi|627657|pir||A54277 transcription adaptor protein p300 - human
 gi|495301|gb|AAA18639.1| p300 protein
          Length = 2414

 Score =  530 bits (1365), Expect = e-148
 Identities = 401/903 (44%), Positives = 497/903 (55%), Gaps = 103/903 (11%)

Query: 1   MAENLLD-GPPNPKRAK--LSSPGFSANDNTDFGSLFDLENDLPDELIP---------XX 48
           MAEN+++ GPP+ KR K    +   SA+D TDFGSLFDLE+DLPDELI            
Sbjct: 1   MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60

Query: 49  XXXXXXXXXXVPDAASKHKQLSELLRXXXXXXXXXXXXXXXASSPVXXXXXXXXXXXPNS 108
                     V DAASKHKQLSELLR                                +S
Sbjct: 61  INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVG--------GPGQVMASQAQQSS 112

Query: 109 TNMASLGAMGKSPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATS 168
             +  + +M KSP+ Q   ++PN+      TSGP    +Q+         G++ S     
Sbjct: 113 PGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQP 161

Query: 169 QTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLXXXXXXXXXXXXXXXX 228
             G     NA  N   PG+L + +G  +M        QVMNGS+                
Sbjct: 162 AMGMNTGTNAGMN---PGMLAAGNGQGIMPN------QVMNGSI---GAGRGRQDMQYPN 209

Query: 229 XXXXXTSSVLAETLTQVSPQMAGHAGLNTAQAXXXXXXXXXXXXSPFGQPFSQTGGQQMG 288
                  ++L E L Q SPQM G  GL   Q             +P+G P++Q  GQQ+G
Sbjct: 210 PGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQ---PLKMGMMNNPNPYGSPYTQNPGQQIG 266

Query: 289 ATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMS----QLQTSVGIVPTQAIATGP- 343
           A+G+  Q+ +K  + N+L  F  D K      +PNM           G+V   A   G  
Sbjct: 267 ASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGMGSG 326

Query: 344 --TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPK 401
             TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+ K
Sbjct: 327 AHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGK 386

Query: 402 ACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGA 461
           +CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQQ IL     G+ N   S+G 
Sbjct: 387 SCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNP-SSLGV 445

Query: 462 GQQNATSLSNPNPIDPSSMQRAYAALGLPYM--NXXXXXXXXXXXXXXXXXXXXXXXMRT 519
           GQQ+A +LS  + IDPSS++RAYAALGLPY                           MR 
Sbjct: 446 GQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGMRP 505

Query: 520 LNALGNNPMSVPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTA 579
           ++ +  +PM V  G      Q P+L+S+S L +++ + NP+M   S + ++ SL  +PTA
Sbjct: 506 MSNMSASPMGVNGG---VGVQTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMPTA 559

Query: 580 APPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDM 639
           A PS+TG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGDM
Sbjct: 560 AQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDM 619

Query: 640 YESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPAL-PASGAQPPVIPPAQ 698
           YESAN+R EYYHLLAEKIYKIQKELEEKRRTRL KQ +L N   + P S    P +   Q
Sbjct: 620 YESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQ 679

Query: 699 SVRPPNGPLPLP-----------VNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMN 747
                NGPLP P           + R+    G+N F  MS+      Q P+ PR   P+ 
Sbjct: 680 PGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMA-----QPPIVPRQTPPLQ 734

Query: 748 HSVQMNSMASV-PGMAISPSRMPQPPNMMGTHANNIMAQAPTQNQFLPQNQFPSSSGAMS 806
           H  Q+    ++ P M   P RM QP N               Q QFLPQ QFPS    M+
Sbjct: 735 HHGQLAQPGALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQ--GMN 776

Query: 807 VNSVGMGQPAAQAGVSQGQEPGAALP--NPLNMLAPQASQLPCPPVTQSPLH---PTPPP 861
           V ++ +   + QA VSQ Q   ++ P  +P+     Q S + CP + Q  LH   P+P P
Sbjct: 777 VTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVP 836

Query: 862 AST 864
           + T
Sbjct: 837 SRT 839




 Score =  118 bits (296), Expect = 1e-24
 Identities = 123/443 (27%), Positives = 165/443 (37%), Gaps = 68/443 (15%)

Query: 1988 GMGTPGSQMTPVGLN--VPRPNQVSG----PVMSSMXXXXXXXXXXXXXXXXXXXXXXVM 2041
            GMG  G Q  P      +P+P Q+      P M S+                       +
Sbjct: 1983 GMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQP-----------------L 2025

Query: 2042 SMQAQAAVAGPRMPNVQPNRSISPSALQDLLRTLKXXXXXXXXXXVLNILKSNPQLMAAF 2101
            +M  Q  +    +  ++P  ++S  ALQ+LLRTL+          VL+IL +NPQL+AAF
Sbjct: 2026 NMAPQPGLGQVGISPLKPG-TVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAF 2084

Query: 2102 IKQRTAKY-------VANXXXXXXXXXXXXXXXXXXXXXXXXXXSLQNLNAM------XX 2148
            IKQR AKY       +                            ++QN+N M        
Sbjct: 2085 IKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAG 2144

Query: 2149 XXXXXXXXXXXXXMGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRRXXXXXXXXXXXX 2208
                         MGG++PQ Q +N+       N   M  Q+R+++RR            
Sbjct: 2145 LPQQQPQQQLQPPMGGMSPQAQQMNM-------NHNTMPSQFRDILRRQQMMQQQQQQGA 2197

Query: 2209 XXXXXXXXNSASLAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSXXXXXXXXX 2268
                        +  GMA H+QFQQPQG  GY P  QQ+       +Q  +         
Sbjct: 2198 ---------GPGIGPGMANHNQFQQPQGV-GYPPQPQQRMQHHMQQMQQGNMGQIGQLPQ 2247

Query: 2269 XXXXXXXXXXXADSTPNXXXXXXXXXXXXXXXXXXXGSPGQPNPMSPQQHMLSGQPQASH 2328
                       A                        GSP QPNPMSPQQHML  Q Q+ H
Sbjct: 2248 ALGAEAGASLQA--------------YQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPH 2293

Query: 2329 LPGQQIATSLSNQVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGTPHPGLAV 2388
            L GQQI  SLSNQV                                    T +PHPGL  
Sbjct: 2294 LQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVA 2353

Query: 2389 TMASSMDQGHLGNPEQSAMLPQL 2411
              A+ M+QGH  +P+Q++ML QL
Sbjct: 2354 AQANPMEQGHFASPDQNSMLSQL 2376



>gi|547239|gb|AAB31182.1| p300=transcription coactivator {N-terminal} [mice, Peptide Partial,
           688 aa]
          Length = 688

 Score =  498 bits (1281), Expect = e-139
 Identities = 343/705 (48%), Positives = 415/705 (58%), Gaps = 61/705 (8%)

Query: 1   MAENLLD-GPPNPKRAK--LSSPGFSANDNTDFGSLFDLENDLPDELIP---------XX 48
           MAEN+++ GPP+ KR K    +   SA+D TDFGSLFDLE+DLPDELI            
Sbjct: 1   MAENVVEPGPPSAKRLKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60

Query: 49  XXXXXXXXXXVPDAASKHKQLSELLRXXXXXXXXXXXXXXXASSPVXXXXXXXXXXXPNS 108
                     V DAASKHKQLSELLR                +               NS
Sbjct: 61  SSQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQA--------MASQACQNS 112

Query: 109 TNMASLGAMGKSPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATS 168
             ++ + +M KSP+     ++PN+      +SGP    +Q+         G++ S     
Sbjct: 113 PGLSLINSMVKSPMACTGLTSPNM---GIGSSGPNQGPTQS-------PAGMMNSPVNQP 162

Query: 169 QTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLXXXXXXXXXXXXXXXX 228
             G    MNA  N   PG+L + +G  +M        QVMNGS+                
Sbjct: 163 AMGMNTGMNAGMN---PGMLAAGNGQGIMPN------QVMNGSI---GAGRGRPNMQYPN 210

Query: 229 XXXXXTSSVLAETLTQVSPQMAGHAGLNTAQAXXXXXXXXXXXXSPFGQPFSQTGGQQMG 288
                  S+L E L Q SPQM G  GL   Q             SP+G P++Q  GQQ+G
Sbjct: 211 AGMGNAGSLLTEPLQQGSPQMGGQPGLRGPQ---PLKMGMMNNPSPYGSPYTQNSGQQIG 267

Query: 289 ATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMSQLQT----SVGIVPTQAIATGP- 343
           A+G+  Q+ +K  + N+L  F  D K      +P+M Q  T      G+V   A   G  
Sbjct: 268 ASGLGLQIQTKTVLPNNLSPFAMDKKAVPGGGMPSMGQQPTPSVQQPGLVTPVAAGMGSG 327

Query: 344 --TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPK 401
             TADPEKR +IQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+ K
Sbjct: 328 AHTADPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGK 387

Query: 402 ACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGA 461
           +CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQ +IL     G+ N   S+G 
Sbjct: 388 SCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGNP-SSLGV 446

Query: 462 GQQNATSLSNPNPIDPSSMQRAYAALGLPYM--NXXXXXXXXXXXXXXXXXXXXXXXMRT 519
           GQQ+  SLS  + IDPSS++RAYAALGLPY                           MR+
Sbjct: 447 GQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQIPPQPQVQAKNQQSQPSGQSPQGMRS 506

Query: 520 LNALGNNPMSVPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTA 579
           +N +  +PM V  G      Q PNL+S+S L +++ + NP+M   S +  + SL  +PTA
Sbjct: 507 VNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINSQNPMM---SGNAGVASLGPLPTA 560

Query: 580 APPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDM 639
           A PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGDM
Sbjct: 561 AQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDM 620

Query: 640 YESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPAL 684
           YESAN+R EYYHLLAEKIYKIQKELEEKRRTRL KQ +L N P +
Sbjct: 621 YESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGM 665



>gi|28486616|ref|XP_283295.1| similar to E1A-associated protein p300 [Mus musculus]
 gi|29244384|ref|NP_808489.1| hypothetical protein A730011L11 [Mus musculus]
 gi|26335221|dbj|BAC31311.1| unnamed protein product [Mus musculus]
          Length = 714

 Score =  483 bits (1242), Expect = e-134
 Identities = 353/732 (48%), Positives = 427/732 (58%), Gaps = 62/732 (8%)

Query: 1   MAENLLD-GPPNPKRAK--LSSPGFSANDNTDFGSLFDLENDLPDELIP---------XX 48
           MAEN+++ GPP+ KR K    +   SA+D TDFGSLFDLE+DLPDELI            
Sbjct: 1   MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60

Query: 49  XXXXXXXXXXVPDAASKHKQLSELLRXXXXXXXXXXXXXXXASSPVXXXXXXXXXXXPNS 108
                     V DAASKHKQLSELLR                +               NS
Sbjct: 61  ISQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQA--------MASQAQQNS 112

Query: 109 TNMASLGAMGKSPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATS 168
             ++ + +M KSP+ Q   ++PN+      +SGP    +Q+         G++ S     
Sbjct: 113 PGLSLINSMVKSPMAQTGLTSPNM---GIGSSGPNQGPTQS-------PAGMMNSPVNQP 162

Query: 169 QTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLXXXXXXXXXXXXXXXX 228
             G    MNA  N   PG+L + +G  +M        QVMNGS+                
Sbjct: 163 AMGMNTGMNAGMN---PGMLAAGNGQGIMPN------QVMNGSI---GAGRGRPNMQYPN 210

Query: 229 XXXXXTSSVLAETLTQVSPQMAGHAGLNTAQAXXXXXXXXXXXXSPFGQPFSQTGGQQMG 288
                  S+L E L Q SPQM G  GL   Q             SP+G P++Q  GQQ+G
Sbjct: 211 AGMGNAGSLLTEPLQQGSPQMGGQPGLRGPQ---PLKMGMMNNPSPYGSPYTQNSGQQIG 267

Query: 289 ATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMSQLQT----SVGIVPTQAIATGP- 343
           A+G+  Q+ +K  + N+L  F  D K      +P+M Q  T      G+V   A   G  
Sbjct: 268 ASGLGLQIQTKTVLPNNLSPFAMDKKAVPGGGMPSMGQQPTPSVQQPGLVTPVAAGMGSG 327

Query: 344 --TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPK 401
             TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+ K
Sbjct: 328 AHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGK 387

Query: 402 ACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGA 461
           +CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQQ+IL     G+ N   S+G 
Sbjct: 388 SCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQSILTGAPVGLGNP-SSLGV 446

Query: 462 GQQNATSLSNPNPIDPSSMQRAYAALGLPYM--NXXXXXXXXXXXXXXXXXXXXXXXMRT 519
           GQQ+  SLS  + IDPSS++RAYAALGLPY                           MR+
Sbjct: 447 GQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQIPPQPQVQAKNQQSQPSGQSPQGMRS 506

Query: 520 LNALGNNPMSVPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTA 579
           +N +  +PM V  G      Q PNL+S+S L +++ + NP+M   S +  + SL  +PTA
Sbjct: 507 VNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINSQNPMM---SENAGVASLGPLPTA 560

Query: 580 APPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDM 639
           A PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGDM
Sbjct: 561 AQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDM 620

Query: 640 YESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPAL-PASGAQPPVIPPAQ 698
           YESAN+R EYYHLLAEKIYKIQKELEEKRRTRL KQ +L N P + P        +    
Sbjct: 621 YESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAPGMGPVPMNTGSNMGQQP 680

Query: 699 SVRPPNGPLPLP 710
           +    NGP+P P
Sbjct: 681 TGMTTNGPVPDP 692



>gi|19173734|ref|NP_596872.1| CREB binding protein; Creb binding protein (CBP) [Rattus
           norvegicus]
 gi|15076624|dbj|BAB62424.1| CREB-binding protein [Rattus norvegicus]
          Length = 351

 Score =  449 bits (1155), Expect = e-124
 Identities = 273/351 (77%), Positives = 276/351 (78%)

Query: 1   MAENLLDGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIPXXXXXXXXXXXXVP 60
           MAENLLDGPPNPKRAKLSSPGFSAND+TDFGSLFDLENDLPDELIP            VP
Sbjct: 1   MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGELSLLNSGNLVP 60

Query: 61  DAASKHKQLSELLRXXXXXXXXXXXXXXXASSPVXXXXXXXXXXXPNSTNMASLGAMGKS 120
           DAASKHKQLSELLR               ASSPV           PNST+MASLGAMGKS
Sbjct: 61  DAASKHKQLSELLRGGSGSSITPGIGNVSASSPVQQGLGGQAQGQPNSTSMASLGAMGKS 120

Query: 121 PLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANF 180
           PLN GDSSTP+LPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANF
Sbjct: 121 PLNPGDSSTPSLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANF 180

Query: 181 NQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLXXXXXXXXXXXXXXXXXXXXXTSSVLAE 240
           NQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSL                     TSSVLAE
Sbjct: 181 NQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLGAAGRGRGAGMPYPAPAMQGATSSVLAE 240

Query: 241 TLTQVSPQMAGHAGLNTAQAXXXXXXXXXXXXSPFGQPFSQTGGQQMGATGVNPQLASKQ 300
           TLTQVSPQMAGHAGLNTAQA            SPFGQPFSQTGGQ MGATGVNPQLASKQ
Sbjct: 241 TLTQVSPQMAGHAGLNTAQAGGMTKMGMTGNTSPFGQPFSQTGGQPMGATGVNPQLASKQ 300

Query: 301 SMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRK 351
           SMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVP Q IATGPTADPEKRK
Sbjct: 301 SMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPAQGIATGPTADPEKRK 351



>gi|27663074|ref|XP_235502.1| similar to E1A-associated protein p300 [Rattus norvegicus]
          Length = 2156

 Score =  392 bits (1008), Expect = e-107
 Identities = 252/513 (49%), Positives = 309/513 (60%), Gaps = 60/513 (11%)

Query: 387 MKNVLNHMTHCQAPKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILG 446
           MKNVLNHMTHCQ+ K+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQQ+IL 
Sbjct: 1   MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQSILT 60

Query: 447 SPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSMQRAYAALGLPYM--NXXXXXXXXXXX 504
               G+ N   S+G GQQ+  SLS  + IDPSS++RAYAALGLPY               
Sbjct: 61  GAPVGLGNP-SSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQIPPQPPVQAKN 119

Query: 505 XXXXXXXXXXXXMRTLNALGNNPMSVPAGGITTDQQPPNLISESALPTSLGATNPLMNDG 564
                       MR++N +  +PM V  G      Q PNL+S+S L +++ + NP+MN+ 
Sbjct: 120 QQSQPSGQSPQGMRSMNNMSASPMGVNGG---VGVQTPNLLSDSMLHSTINSQNPMMNE- 175

Query: 565 SNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRR 624
             + ++ SL  +PTAA PSSTG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRR
Sbjct: 176 --NASVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRR 233

Query: 625 MENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPAL 684
           MENLVAYA+KVEGDMYESAN+R EYYHLLAEKIYKIQKELEEKRRTRL KQ +L + P +
Sbjct: 234 MENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPSAPGM 293

Query: 685 --------PASGAQPPVIPPAQ------SVRPPNGPLPLP-----------VNRMQVSQG 719
                   P  G QP  +          SV  P+GPLP P           + RM    G
Sbjct: 294 VPVPMNTAPNMGQQPTGMTTKTKGYLTISVSTPDGPLPDPSMIRGSVPNQMMPRMTPQPG 353

Query: 720 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMASV-PGMAISPSRMPQPPNMMGTH 778
           +N F     G + +PQ P+GPR  SP+ H  Q+    S+ P M   P             
Sbjct: 354 LNQF-----GQMNIPQPPIGPRQPSPLQHHGQLAQSGSLNPPMGYGPR------------ 396

Query: 779 ANNIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQEPGAALP--NPLN 836
               M Q   QNQFL Q QFPS    M+V ++ +   ++QA VSQ Q   ++ P  +P+ 
Sbjct: 397 ----MQQTSGQNQFLSQTQFPSQ--GMNVTNMPLAPSSSQAPVSQAQMSSSSCPVNSPIM 450

Query: 837 MLAPQASQLPCPPVTQSPLHPTPPPASTAAGMP 869
               Q S + CP + Q     +P P  +    P
Sbjct: 451 PPGSQGSHIHCPTLPQQAHQNSPSPVPSRTPTP 483




 Score =  117 bits (294), Expect = 2e-24
 Identities = 127/444 (28%), Positives = 167/444 (37%), Gaps = 68/444 (15%)

Query: 1988 GMGTPGSQMTP--VGLNVPRPNQVSG----PVMSSMXXXXXXXXXXXXXXXXXXXXXXVM 2041
            GMG  G Q  P      +P+P Q+      P M S+                       +
Sbjct: 1662 GMGPAGMQQQPPWAQGGMPQPQQMQSGMPRPAMMSVAQHGQP-----------------L 1704

Query: 2042 SMQAQAAVAGPRMPNVQPNRSISPSALQDLLRTLKXXXXXXXXXXVLNILKSNPQLMAAF 2101
            +M  Q  +    +  ++P  ++S  ALQ+LLRTL+          VL+IL +NPQL+AAF
Sbjct: 1705 NMAPQPGLGQVGVSPLKPG-TVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAF 1763

Query: 2102 IKQRTAKY-------VANXXXXXXXXXXXXXXXXXXXXXXXXXXSLQNLNAM------XX 2148
            IKQR AKY       +                            +LQN+N M        
Sbjct: 1764 IKQRAAKYANSNPQPLPGQPGMPQGQPGLQPPTMPGQQGVHSNPALQNMNPMQAGVQRAG 1823

Query: 2149 XXXXXXXXXXXXXMGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRRXXXXXXXXXXXX 2208
                         MGG++PQ Q +N+       N   M  Q+R+++RR            
Sbjct: 1824 LPQQQPQQQLQPPMGGMSPQAQQMNM-------NHNTMPSQFRDILRRQMMQQQGA---- 1872

Query: 2209 XXXXXXXXNSASLAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSXXXXXXXXX 2268
                        +  GMA H+QFQQPQG  GY P  QQQ+ QQ +               
Sbjct: 1873 ---------GPGIGPGMANHNQFQQPQGI-GYPPQQQQQQQQQRMQHHMQQMQQGNMGQM 1922

Query: 2269 XXXXXXXXXXXADSTPNXXXXXXXXXXXXXXXXXXXGSPGQPNPMSPQQHMLSGQPQASH 2328
                         S                      GSP QPNPMSPQQHML  Q Q+ H
Sbjct: 1923 GQLPQALGAEAGAS---------LQAYQQRLLQQQMGSPAQPNPMSPQQHMLPNQAQSPH 1973

Query: 2329 LPGQQIATSLSNQVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGTPHPGL-A 2387
            L GQQI  SLSNQV                                    T +PHPGL A
Sbjct: 1974 LQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVA 2033

Query: 2388 VTMASSMDQGHLGNPEQSAMLPQL 2411
               A+ M+QGH  +P+Q++ML QL
Sbjct: 2034 AQAANPMEQGHFASPDQNSMLSQL 2057



>gi|9368432|emb|CAB98139.1| MOZ/CBP protein [Homo sapiens]
          Length = 376

 Score =  366 bits (940), Expect = 2e-99
 Identities = 228/330 (69%), Positives = 238/330 (72%), Gaps = 1/330 (0%)

Query: 13  KRAKLSSPGFSANDNTDFGSLFDLENDLPDELIP-XXXXXXXXXXXXVPDAASKHKQLSE 71
           +++K       ++D  DFGSLFDLENDLPDELIP             VPDAASKHKQLSE
Sbjct: 47  RKSKDEEEDEESDDADDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSE 106

Query: 72  LLRXXXXXXXXXXXXXXXASSPVXXXXXXXXXXXPNSTNMASLGAMGKSPLNQGDSSTPN 131
           LLR               ASSPV           PNS NMASL AMGKSPL+QGDSS P+
Sbjct: 107 LLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPS 166

Query: 132 LPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANFNQTHPGLLNSN 191
           LPKQAASTSGPTP ASQALNPQAQKQVGL TSSPATSQTGPGICMNANFNQTHPGLLNSN
Sbjct: 167 LPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSN 226

Query: 192 SGHSLMNQAQQGQAQVMNGSLXXXXXXXXXXXXXXXXXXXXXTSSVLAETLTQVSPQMAG 251
           SGHSL+NQA QGQAQVMNGSL                     +SSVLAETLTQVSPQM G
Sbjct: 227 SGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTG 286

Query: 252 HAGLNTAQAXXXXXXXXXXXXSPFGQPFSQTGGQQMGATGVNPQLASKQSMVNSLPAFPT 311
           HAGLNTAQA            SPFGQPFSQ GGQ MGATGVNPQLASKQSMVNSLP FPT
Sbjct: 287 HAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPT 346

Query: 312 DIKNTSVTTVPNMSQLQTSVGIVPTQAIAT 341
           DIKNTSVT VPNMSQ+QTSVGIVPTQAIAT
Sbjct: 347 DIKNTSVTNVPNMSQMQTSVGIVPTQAIAT 376



>gi|28486618|ref|XP_128116.2| similar to E1A-associated protein p300 [Mus musculus]
          Length = 234

 Score =  339 bits (870), Expect = 4e-91
 Identities = 148/172 (86%), Positives = 156/172 (90%)

Query: 1379 RFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSI 1438
            RFVDSGEM+ESFPYRTKALFAFEEIDGVD+CFFGMHVQ+     P   Q  VYISYLDS+
Sbjct: 10   RFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSV 69

Query: 1439 HFFRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPK 1498
            HFFRP+CLRTAVYHEILIGYLEYVKKL Y T HIWACPPSEGDDYIFHCHPPDQKIPKPK
Sbjct: 70   HFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPK 129

Query: 1499 RLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVL 1550
            RLQEWYKKMLDKA +ERI++DYKDI KQA EDRLTSAKELPYFEGDFWPNVL
Sbjct: 130  RLQEWYKKMLDKAVSERIVHDYKDILKQATEDRLTSAKELPYFEGDFWPNVL 181



>gi|27667568|ref|XP_213219.1| similar to CREB-binding protein [Mus musculus] [Rattus norvegicus]
          Length = 132

 Score =  284 bits (727), Expect = 1e-74
 Identities = 131/132 (99%), Positives = 131/132 (99%)

Query: 1096 MPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYV 1155
            MPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYV
Sbjct: 1    MPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYV 60

Query: 1156 DDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCY 1215
            DDV LMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCY
Sbjct: 61   DDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCY 120

Query: 1216 GKQLCTIPRDAA 1227
            GKQLCTIPRDAA
Sbjct: 121  GKQLCTIPRDAA 132



>gi|21307831|gb|AAL54859.1| CREB-binding protein [Aplysia californica]
          Length = 2245

 Score =  266 bits (681), Expect = 3e-69
 Identities = 229/610 (37%), Positives = 294/610 (48%), Gaps = 82/610 (13%)

Query: 125 GDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPA---TSQTGPGICMNANFN 181
           GD  TP    Q  S  G          P +Q  + L  +S     TS++     M     
Sbjct: 56  GDGQTPQ-GSQDTSMGGSLSQLLSRSTPNSQTSLPLPVNSAGGIQTSRSPGMGAMMNMGM 114

Query: 182 QTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLXXXXXXXXXXXXXXXXXXXXXTSSVLAET 241
             +P  +++N   +L N+A       MN +L                     T   +   
Sbjct: 115 GKNP--MSNNLAATLANKAATSSHMNMNDALVSSASFTISGTNAGPMGGVTNT---MGMN 169

Query: 242 LTQVSPQMAGHAG-LNTAQAXXXXXXXXXXXXSPFGQPFSQTGGQQMGATGVNPQLASK- 299
            T  +PQM G  G LN  Q              P   P +    + M    VNP  + + 
Sbjct: 170 PTMGNPQMIGSVGSLNMNQQ-----MPNQMMNGPTSFPGNMGQMRAMQGNNVNPSTSMQV 224

Query: 300 -QSMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIV----PTQAIATGP---TADPEKRK 351
            Q+ +   P  P    +  +   PNM+  Q     +    PT +  +GP     +P+K K
Sbjct: 225 PQTGMMQSPGMPQMQGHQGMPGHPNMNMPQNPPQNIRPGQPTGSGTSGPRQAAGEPDKSK 284

Query: 352 LIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASS 411
           LIQQQLVLLLHAHKCQRREQ N E + C LP+CRTMKNVLNHMT C   K+C+VAHCASS
Sbjct: 285 LIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKGKSCEVAHCASS 343

Query: 412 RQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSN 471
           RQII+HWKNC R DCPVC  LK A DKRN Q                 G      ++++ 
Sbjct: 344 RQIITHWKNCLRQDCPVCFALKIA-DKRNTQ-----------------GQSVNQTSTMTA 385

Query: 472 PNPIDPSSMQRAYAALGLPYMNXXXXXXXXXXXXXXXXXXXXXXXMRTLNALGNNPMSVP 531
           PN  DP++M+RA+ +LGL Y                            +NA+ N+   + 
Sbjct: 386 PNAADPATMKRAFESLGLQYNQNTPAHNAAQHGHP------------QMNAMQNDAGQIN 433

Query: 532 AGGITTDQQPPNLISESALPTSLGATNP---------------LMNDGSNSGNIGSLSTI 576
              +   Q P  +  +S+ P S+    P               L +  + +  +G+   I
Sbjct: 434 KTNMPNQQGPKVVPDQSSSPMSMLPVPPTGQLPQTIQPQSGTQLASATAQAAAMGNAPDI 493

Query: 577 PTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVE 636
             + P SS   RK WH  VTQDLR+HLVHKLVQAIFPTPD A L+D RM+NLVAYA+KVE
Sbjct: 494 VKSIPVSS---RKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARKVE 550

Query: 637 GDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPALPASGAQPPVIPP 696
           GDMYESAN+R +YYHLLAEKIYKIQKELEEKR  R+  Q    N P     G Q  + P 
Sbjct: 551 GDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQ----NAPNAQVPGMQGQIHPN 606

Query: 697 AQSVRPPNGP 706
           AQ     NGP
Sbjct: 607 AQ-----NGP 611



>gi|23200188|pdb|1JSP|B Chain B, Nmr Structure Of Cbp Bromodomain In Complex With P53 Peptide
          Length = 121

 Score =  244 bits (624), Expect = 1e-62
 Identities = 117/120 (97%), Positives = 117/120 (97%)

Query: 1079 SQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLST 1138
            S  RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLST
Sbjct: 2    SHMRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLST 61

Query: 1139 IKRKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG 1198
            IKRKLDTGQYQEPWQYVDDV LMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG
Sbjct: 62   IKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG 121



>gi|21105780|gb|AAM34788.1|AF512558_2 HAC5 [Arabidopsis thaliana]
          Length = 1012

 Score =  239 bits (610), Expect = 4e-61
 Identities = 148/388 (38%), Positives = 210/388 (54%), Gaps = 52/388 (13%)

Query: 1200 CCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSY---QNRYHFCGKCFTEIQGENVTLGDDP 1256
            C   +  F P  + C       + R+A +Y+    ++R++ C  C+ E +   V++   P
Sbjct: 405  CAVERLAFEPTPIYCTPCG-ARVKRNAMHYTVVAGESRHYVCIPCYNEARANTVSVDGTP 463

Query: 1257 SQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSG---FVCDNCL 1313
                  + K +FEKKKND    E +V C +C    HQIC L ++     G   + C NC 
Sbjct: 464  ------VPKSRFEKKKNDEEVEESWVQCDKCQAWQHQICAL-FNGRRNHGQAEYTCPNCY 516

Query: 1314 -----KKTGRPRKENK-FSAKRLQTTRLGNHLEDRVNKFLRRQNH-------------PE 1354
                 +   +P  +N    AK L  + L NHLE R+ K L+++               P 
Sbjct: 517  IQEVEQGERKPVSQNVILGAKSLPASTLSNHLEQRLFKKLKQERQERARLQGKSYEEVPG 576

Query: 1355 AGEVFVRVVASSDKTVEVKPGMKSRFVD---SGEMSESFPYRTKALFAFEEIDGVDVCFF 1411
            A  + +RVVAS DK +EVKP    RF+D       S  FPY++KA+  F++I+GV+VC F
Sbjct: 577  ADSLVIRVVASVDKILEVKP----RFLDIFREDNYSSEFPYKSKAILLFQKIEGVEVCLF 632

Query: 1412 GMHVQDTALIAPHQIQGCVYISYLDSIHFFRP-------RCLRTAVYHEILIGYLEYVKK 1464
            GM+VQ+    +    Q  VY+SYLDS+ +FRP         LRT VYHEILIGYL+Y KK
Sbjct: 633  GMYVQEFGTDSASPNQRRVYLSYLDSVKYFRPDVRTVSGEALRTFVYHEILIGYLDYCKK 692

Query: 1465 LVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERII----NDY 1520
              + + +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  E+++    N Y
Sbjct: 693  RGFSSCYIWACPPLKGEDYILYCHPEIQKTPKTDKLREWYLAMLKKASKEKVVVECTNFY 752

Query: 1521 KDIFKQANEDRL-TSAKELPYFEGDFWP 1547
               F Q+ E R   +A  LPYF+GD+WP
Sbjct: 753  DHFFVQSGECRAKVTAARLPYFDGDYWP 780




 Score = 75.9 bits (185), Expect = 9e-12
 Identities = 41/129 (31%), Positives = 66/129 (51%), Gaps = 8/129 (6%)

Query: 1616 NDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDK 1675
            N + ++ +   +K K V + + +   P       I D D +L  +  D R AFL+L +  
Sbjct: 889  NRVEKEKHPVNQKEKHVLYPVAIDNIPT-----EIKDNDDILESEFFDTRQAFLSLCQGN 943

Query: 1676 HWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETR--WHCTVCEDYDLCINC 1733
            H+++ +LRR+K S++ +L  LH      F   C  C+  +ET   W C VC DYD+C  C
Sbjct: 944  HYQYDTLRRAKHSSMMILYHLHNPTVPAFAMACAICQQELETAQGWRCEVCPDYDVCNAC 1003

Query: 1734 YNTK-SHTH 1741
            Y+   +H H
Sbjct: 1004 YSKGINHPH 1012




 Score = 65.9 bits (159), Expect = 8e-09
 Identities = 32/86 (37%), Positives = 48/86 (55%), Gaps = 7/86 (8%)

Query: 357 LVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQIIS 416
           L+ LLH  KC   E        C   +C T K +L H+  C+AP AC   +C  +RQ+I 
Sbjct: 94  LLFLLHVRKCNAAED------NCESKYCFTAKTLLKHINCCKAP-ACAYQYCHQTRQLIH 146

Query: 417 HWKNCTRHDCPVCLPLKNASDKRNQQ 442
           H+K+C    CPVC+ +KN  +K+ ++
Sbjct: 147 HYKHCGDEACPVCVFVKNFKEKQKEK 172



>gi|15230656|ref|NP_187904.1| CREB-binding protein -related [Arabidopsis thaliana]
 gi|15795129|dbj|BAB02507.1| CREB-binding protein-like [Arabidopsis thaliana]
          Length = 1670

 Score =  232 bits (591), Expect = 8e-59
 Identities = 147/387 (37%), Positives = 208/387 (53%), Gaps = 50/387 (12%)

Query: 1200 CCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSY---QNRYHFCGKCFTEIQGENVTLGDDP 1256
            C   +  F P  + C       + R+A +Y+    ++R++ C  C+ E +   V++   P
Sbjct: 933  CAVERLAFEPTPIYCTPCG-ARVKRNAMHYTVVAGESRHYVCIPCYNEARANTVSVDGTP 991

Query: 1257 SQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDII--WPSGFVCDNCL- 1313
                  + K +FEKKKND    E +V C +C    HQIC L         + + C NC  
Sbjct: 992  ------VPKSRFEKKKNDEEVEESWVQCDKCQAWQHQICALFNGRRNHGQAEYTCPNCYI 1045

Query: 1314 ----KKTGRPRKENK-FSAKRLQTTRLGNHLEDRVNKFLRRQNH-------------PEA 1355
                +   +P  +N    AK L  + L NHLE R+ K L+++               P A
Sbjct: 1046 QEVEQGERKPVSQNVILGAKSLPASTLSNHLEQRLFKKLKQERQERARLQGKSYEEVPGA 1105

Query: 1356 GEVFVRVVASSDKTVEVKPGMKSRFVD---SGEMSESFPYRTKALFAFEEIDGVDVCFFG 1412
              + +RVVAS DK +EVKP    RF+D       S  FPY++KA+  F++I+GV+VC FG
Sbjct: 1106 DSLVIRVVASVDKILEVKP----RFLDIFREDNYSSEFPYKSKAILLFQKIEGVEVCLFG 1161

Query: 1413 MHVQDTALIAPHQIQGCVYISYLDSIHFFRP-------RCLRTAVYHEILIGYLEYVKKL 1465
            M+VQ+    +    Q  VY+SYLDS+ +FRP         LRT VYHEILIGYL+Y KK 
Sbjct: 1162 MYVQEFGTDSASPNQRRVYLSYLDSVKYFRPDVRTVSGEALRTFVYHEILIGYLDYCKKR 1221

Query: 1466 VYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERII----NDYK 1521
             + + +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  E+++    N Y 
Sbjct: 1222 GFSSCYIWACPPLKGEDYILYCHPEIQKTPKTDKLREWYLAMLKKASKEKVVVECTNFYD 1281

Query: 1522 DIFKQANEDRL-TSAKELPYFEGDFWP 1547
              F Q+ E R   +A  LPYF+GD+WP
Sbjct: 1282 HFFVQSGECRAKVTAARLPYFDGDYWP 1308




 Score =  110 bits (275), Expect = 3e-22
 Identities = 66/236 (27%), Positives = 115/236 (48%), Gaps = 20/236 (8%)

Query: 1616 NDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDK 1675
            N + ++ +   +K K V + + +   P       I D D +L  +  D R AFL+L +  
Sbjct: 1417 NRVEKEKHPVNQKEKHVLYPVAIDNIPT-----EIKDNDDILESEFFDTRQAFLSLCQGN 1471

Query: 1676 HWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETR--WHCTVCEDYDLCINC 1733
            H+++ +LRR+K S++ +L  LH      F   C  C+  +ET   W C VC DYD+C  C
Sbjct: 1472 HYQYDTLRRAKHSSMMILYHLHNPTVPAFAMACAICQQELETAQGWRCEVCPDYDVCNAC 1531

Query: 1734 YNTK-SHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCS 1792
            Y+   +H H ++      D    +    Q ++ Q           + L+H   C  A C 
Sbjct: 1532 YSKGINHPHSIISRPSATDSVVQNTQTNQIQNAQLR---------EVLLHVMTCCTAQCQ 1582

Query: 1793 LPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIK 1848
             P C+ +K +++H   CK +   GC  CK++ +L   H+++C++ +C VP C  ++
Sbjct: 1583 YPRCRVIKGLIRHGLVCKTR---GCIACKKMWSLFRLHSRNCRDPQCKVPKCRELR 1635




 Score = 64.3 bits (155), Expect = 3e-08
 Identities = 32/86 (37%), Positives = 48/86 (55%), Gaps = 7/86 (8%)

Query: 357 LVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQIIS 416
           L+ LLH  KC   E        C   +C T K +L H+  C+AP AC   +C  +RQ+I 
Sbjct: 622 LLFLLHVRKCNAAED------NCESKYCFTAKTLLKHINCCKAP-ACAYQYCHQTRQLIH 674

Query: 417 HWKNCTRHDCPVCLPLKNASDKRNQQ 442
           H+K+C    CPVC+ +KN  +K+ ++
Sbjct: 675 HYKHCGDEACPVCVFVKNFKEKQKEK 700



>gi|7487910|pir||T01055 hypothetical protein YUP8H12R.38 - Arabidopsis thaliana
 gi|3152587|gb|AAC17068.1| Similar to CREB-binding protein homolog gb|U88570 from D.
            melanogaster and contains similarity to callus-associated
            protein gb|U01961 from Nicotiana tabacum.  EST gb|W43427
            comes from this gene. [Arabidopsis thaliana]
          Length = 1516

 Score =  218 bits (555), Expect = 1e-54
 Identities = 144/385 (37%), Positives = 196/385 (50%), Gaps = 45/385 (11%)

Query: 1200 CCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSY---QNRYHFCGKCFTEIQGENVTLGDDP 1256
            C   K  F P  + C       I R+A YY+      R++FC  C+ E +G+ +     P
Sbjct: 832  CAVEKLTFEPPPIYCTPCG-ARIKRNAMYYTVGAGDTRHYFCIPCYNESRGDTILAEGTP 890

Query: 1257 SQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVL---------HYDIIWPSGF 1307
                  + K + EKKKND    E +V C +C    HQIC L           +   P  F
Sbjct: 891  ------MPKARLEKKKNDEETEEWWVQCDKCEAWQHQICALFNGRRNDGGQAEYTCPYCF 944

Query: 1308 VCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNH-------------PE 1354
            + +    K     +     AK L  T L +H+E R+ K L+++               P 
Sbjct: 945  IAEVEQSKRKPLPQSAVLGAKDLPRTILSDHIEQRLFKRLKQERTERARAQGKSYDEIPT 1004

Query: 1355 AGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMH 1414
            A  + +RVV+S DK +EVKP     F +    +E F Y++K +  F++I+GV+VC FGM+
Sbjct: 1005 AESLVIRVVSSVDKKLEVKPRFLEIFREDSYPTE-FAYKSKVVLLFQKIEGVEVCLFGMY 1063

Query: 1415 VQDTALIAPHQIQGCVYISYLDSIHFFRP-------RCLRTAVYHEILIGYLEYVKKLVY 1467
            VQ+         Q  VY+SYLDS+ +FRP         LRT VYHEILIGYLEY K   +
Sbjct: 1064 VQEFGSECAFPNQRRVYLSYLDSVKYFRPEVRSYNGEALRTFVYHEILIGYLEYCKLRGF 1123

Query: 1468 VTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERI----INDYKDI 1523
             + +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  E I    IN Y   
Sbjct: 1124 TSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLAMLRKASKEGIVAETINLYDHF 1183

Query: 1524 FKQANEDRL-TSAKELPYFEGDFWP 1547
            F Q  E R   +A  LPYF+GD+WP
Sbjct: 1184 FMQTGECRAKVTAARLPYFDGDYWP 1208




 Score =  144 bits (362), Expect = 2e-32
 Identities = 80/229 (34%), Positives = 129/229 (56%), Gaps = 16/229 (6%)

Query: 1621 KLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFS 1680
            +L  T+   KE F ++ +   P  +      D D +L  +  D R AFL+L +  H+++ 
Sbjct: 1298 QLGETIHPMKEDFIMVEIMDIPADTR-----DKDEILESEFFDTRQAFLSLCQGNHYQYD 1352

Query: 1681 SLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVET--RWHCTVCEDYDLCINCYNTK- 1737
            +LRR+K S++ +L  LH      FV TCN C   +ET   W C VC DYD+C  C++   
Sbjct: 1353 TLRRAKHSSMMVLYHLHNPTAPAFVTTCNACHLDIETGQGWRCEVCPDYDVCNACFSRDG 1412

Query: 1738 --SHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPS 1795
              +H HK+      L D+ +     Q+K  ++ R L +++ +  LVHA QCR+A+C  P+
Sbjct: 1413 GVNHPHKLTNHP-SLADQNA-----QNKEARQLRVLQLRKMLDLLVHASQCRSAHCQYPN 1466

Query: 1796 CQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFC 1844
            C+K+K + +H   CK + +GGC +CK++  L   HA+ C+E++C VP C
Sbjct: 1467 CRKVKGLFRHGINCKVRASGGCVLCKKMWYLLQLHARACKESECHVPRC 1515




 Score = 54.7 bits (130), Expect = 2e-05
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 15/140 (10%)

Query: 299 KQSMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIAT-----GPTADPEKRKLI 353
           +Q M  +  A P ++   S+     +S   TS  + P    AT         DP + K  
Sbjct: 461 RQRMSGTDEAQPNNMSGGSIIGQNRVS--TTSESLNPQNPTATTCRNGNGNRDP-RFKNQ 517

Query: 354 QQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQ 413
           Q+ L+ L HA  C+  E        C   +C T++ +  HM  C AP+ C    C  ++ 
Sbjct: 518 QKWLLFLRHARHCKAPEG------KCPDRNCVTVQKLWKHMDSCAAPQ-CSYPRCLPTKT 570

Query: 414 IISHWKNCTRHDCPVCLPLK 433
           +I+H ++C   +CPVC+P+K
Sbjct: 571 LINHHRSCKEPNCPVCIPVK 590



>gi|18412221|ref|NP_565197.1| p300/CBP acetyltransferase-related protein 2 [Arabidopsis thaliana]
 gi|12597461|gb|AAG60059.1| p300/CBP acetyltransferase-related protein 2 [Arabidopsis thaliana]
          Length = 1654

 Score =  216 bits (550), Expect = 4e-54
 Identities = 144/385 (37%), Positives = 196/385 (50%), Gaps = 45/385 (11%)

Query: 1200 CCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSY---QNRYHFCGKCFTEIQGENVTLGDDP 1256
            C   K  F P  + C       I R+A YY+      R++FC  C+ E +G+ +     P
Sbjct: 946  CAVEKLTFEPPPIYCTPCG-ARIKRNAMYYTVGAGDTRHYFCIPCYNESRGDTILAEGTP 1004

Query: 1257 SQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVL---------HYDIIWPSGF 1307
                  + K + EKKKND    E +V C +C    HQIC L           +   P  F
Sbjct: 1005 ------MPKARLEKKKNDEETEEWWVQCDKCEAWQHQICALFNGRRNDGGQAEYTCPYCF 1058

Query: 1308 VCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNH-------------PE 1354
            + +    K     +     AK L  T L +H+E R+ K L+++               P 
Sbjct: 1059 IAEVEQSKRKPLPQSAVLGAKDLPRTILSDHIEQRLFKRLKQERTERARAQGKSYDEIPT 1118

Query: 1355 AGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMH 1414
            A  + +RVV+S DK +EVKP     F +    +E F Y++K +  F++I+GV+VC FGM+
Sbjct: 1119 AESLVIRVVSSVDKKLEVKPRFLEIFREDSYPTE-FAYKSKVVLLFQKIEGVEVCLFGMY 1177

Query: 1415 VQDTALIAPHQIQGCVYISYLDSIHFFRP-------RCLRTAVYHEILIGYLEYVKKLVY 1467
            VQ+         Q  VY+SYLDS+ +FRP         LRT VYHEILIGYLEY K   +
Sbjct: 1178 VQEFGSECAFPNQRRVYLSYLDSVKYFRPEVRSYNGEALRTFVYHEILIGYLEYCKLRGF 1237

Query: 1468 VTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERI----INDYKDI 1523
             + +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  E I    IN Y   
Sbjct: 1238 TSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLAMLRKASKEGIVAETINLYDHF 1297

Query: 1524 FKQANEDRL-TSAKELPYFEGDFWP 1547
            F Q  E R   +A  LPYF+GD+WP
Sbjct: 1298 FMQTGECRAKVTAARLPYFDGDYWP 1322




 Score =  142 bits (357), Expect = 1e-31
 Identities = 74/198 (37%), Positives = 117/198 (59%), Gaps = 11/198 (5%)

Query: 1652 DPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNEC 1711
            D D +L  +  D R AFL+L +  H+++ +LRR+K S++ +L  LH      FV TCN C
Sbjct: 1462 DKDEILESEFFDTRQAFLSLCQGNHYQYDTLRRAKHSSMMVLYHLHNPTAPAFVTTCNAC 1521

Query: 1712 KHHVET--RWHCTVCEDYDLCINCYNTK---SHTHKMVKWGLGLDDEGSSQGEPQSKSPQ 1766
               +ET   W C VC DYD+C  C++     +H HK+      L D+ +     Q+K  +
Sbjct: 1522 HLDIETGQGWRCEVCPDYDVCNACFSRDGGVNHPHKLTNHP-SLADQNA-----QNKEAR 1575

Query: 1767 ESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIAL 1826
            + R L +++ +  LVHA QCR+A+C  P+C+K+K + +H   CK + +GGC +CK++  L
Sbjct: 1576 QLRVLQLRKMLDLLVHASQCRSAHCQYPNCRKVKGLFRHGINCKVRASGGCVLCKKMWYL 1635

Query: 1827 CCYHAKHCQENKCPVPFC 1844
               HA+ C+E++C VP C
Sbjct: 1636 LQLHARACKESECHVPRC 1653




 Score = 54.3 bits (129), Expect = 3e-05
 Identities = 39/139 (28%), Positives = 64/139 (46%), Gaps = 13/139 (9%)

Query: 299 KQSMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIAT----GPTADPEKRKLIQ 354
           +Q M  +  A P ++   S+     +S   TS  + P    AT    G      + K  Q
Sbjct: 575 RQRMSGTDEAQPNNMSGGSIIGQNRVS--TTSESLNPQNPTATTCRNGNGNRDPRFKNQQ 632

Query: 355 QQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVAHCASSRQI 414
           + L+ L HA  C+  E        C   +C T++ +  HM  C AP+ C    C  ++ +
Sbjct: 633 KWLLFLRHARHCKAPEG------KCPDRNCVTVQKLWKHMDSCAAPQ-CSYPRCLPTKTL 685

Query: 415 ISHWKNCTRHDCPVCLPLK 433
           I+H ++C   +CPVC+P+K
Sbjct: 686 INHHRSCKEPNCPVCIPVK 704



>gi|25518555|pir||E86302 hypothetical protein F17F16.8 [imported] - Arabidopsis thaliana
 gi|9954734|gb|AAG09087.1|AC026237_8 Unknown Protein [Arabidopsis thaliana]
          Length = 1498

 Score =  205 bits (522), Expect = 8e-51
 Identities = 146/388 (37%), Positives = 200/388 (51%), Gaps = 51/388 (13%)

Query: 1200 CCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSY---QNRYHFCGKCFTEIQGENVTLGDDP 1256
            C   K  F P  + C       I R+A YY+    + R++FC  C+ E +G+ + L +  
Sbjct: 753  CAVEKLTFEPPPIYCTPCG-ARIKRNAMYYTVGGGETRHYFCIPCYNESRGDTI-LAEGT 810

Query: 1257 SQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVL---------HYDIIWPSGF 1307
            S P     K + EKKKND    E +V C +C    HQIC L           +   P  +
Sbjct: 811  SMP-----KAKLEKKKNDEEIEESWVQCDKCQAWQHQICALFNGRRNDGGQAEYTCPYCY 865

Query: 1308 VCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNH-------------PE 1354
            V D    +     +     AK L  T L +H+E R+ K L+++               P 
Sbjct: 866  VIDVEQNERKPLLQSAVLGAKDLPRTILSDHIEQRLFKRLKQERTERARVQGTSYDEIPT 925

Query: 1355 AGEVFVRVVASSDKTVEVKPGMKSRFVD---SGEMSESFPYRTKALFAFEEIDGVDVCFF 1411
               + VRVV+S DK +EV    KSRF++          FPY++K +  F++I+GV+VC F
Sbjct: 926  VESLVVRVVSSVDKKLEV----KSRFLEIFREDNFPTEFPYKSKVVLLFQKIEGVEVCLF 981

Query: 1412 GMHVQDTALIAPHQIQGCVYISYLDSIHFFRP-------RCLRTAVYHEILIGYLEYVKK 1464
            GM+VQ+      +  Q  VY+SYLDS+ +FRP         LRT VYHEILIGYLEY K 
Sbjct: 982  GMYVQEFGSECSNPNQRRVYLSYLDSVKYFRPDIKSANGEALRTFVYHEILIGYLEYCKL 1041

Query: 1465 LVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERII----NDY 1520
              + + +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  E I+    N Y
Sbjct: 1042 RGFTSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLAMLRKAAKEGIVAETTNLY 1101

Query: 1521 KDIFKQANEDRL-TSAKELPYFEGDFWP 1547
               F Q  E R   +A  LPYF+GD+WP
Sbjct: 1102 DHFFLQTGECRAKVTAARLPYFDGDYWP 1129




 Score =  140 bits (354), Expect = 2e-31
 Identities = 75/206 (36%), Positives = 121/206 (58%), Gaps = 11/206 (5%)

Query: 1652 DPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNEC 1711
            D D +L  +  D R AFL+L +  H+++ +LRR+K S++ +L  LH      FV TCN C
Sbjct: 1269 DRDEILESEFFDTRQAFLSLCQGNHYQYDTLRRAKHSSMMVLYHLHNPTAPAFVTTCNVC 1328

Query: 1712 KHHVET--RWHCTVCEDYDLCINCYNTK---SHTHKMVKWGLGLDDEGSSQGEPQSKSPQ 1766
               +E+   W C VC DYD+C  CY  +   +H HK+      L D+ +     Q+K  +
Sbjct: 1329 HLDIESGLGWRCEVCPDYDVCNACYKKEGCINHPHKLTTHP-SLADQNA-----QNKEAR 1382

Query: 1767 ESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIAL 1826
            + R L +++ +  LVHA QCR+  C  P+C+K+K + +H   CK + +GGC +CK++  L
Sbjct: 1383 QLRVLQLRKMLDLLVHASQCRSPVCLYPNCRKVKGLFRHGLRCKVRASGGCVLCKKMWYL 1442

Query: 1827 CCYHAKHCQENKCPVPFCLNIKHNVR 1852
               HA+ C+E++C VP C ++K ++R
Sbjct: 1443 LQLHARACKESECDVPRCGDLKEHLR 1468




 Score = 57.0 bits (136), Expect = 4e-06
 Identities = 49/186 (26%), Positives = 86/186 (46%), Gaps = 22/186 (11%)

Query: 289 ATGVNPQLASKQSMVNSLPAFPTDIKNTSV------TTVPNMSQLQTSVGIVPTQAIATG 342
           ++G + Q   +Q +     A P ++   SV      +T+     LQ S+G   T      
Sbjct: 370 SSGKHIQEDFRQRITGMDEAQPNNLTEGSVIGQNHTSTISESHNLQNSIG---TTCRYGN 426

Query: 343 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKA 402
            + DP K K  Q+ L+ L HA  C+      G    C   +C T++ + +HM +C  P+ 
Sbjct: 427 VSHDP-KFKNQQRWLLFLRHARSCK---PPGGR---CQDQNCVTVQKLWSHMDNCADPQ- 478

Query: 403 CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAG 462
           C    C  ++ +I H+KNC    CPVC+P+K    + N + +     + ++N   +VG+ 
Sbjct: 479 CLYPRCRHTKALIGHYKNCKDPRCPVCVPVKTYQQQANVRAL-----ARLKNESSAVGSV 533

Query: 463 QQNATS 468
            ++  S
Sbjct: 534 NRSVVS 539



>gi|15219327|ref|NP_173115.1| expressed protein [Arabidopsis thaliana]
          Length = 1706

 Score =  204 bits (519), Expect = 2e-50
 Identities = 146/388 (37%), Positives = 200/388 (51%), Gaps = 51/388 (13%)

Query: 1200 CCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSY---QNRYHFCGKCFTEIQGENVTLGDDP 1256
            C   K  F P  + C       I R+A YY+    + R++FC  C+ E +G+ + L +  
Sbjct: 961  CAVEKLTFEPPPIYCTPCG-ARIKRNAMYYTVGGGETRHYFCIPCYNESRGDTI-LAEGT 1018

Query: 1257 SQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVL---------HYDIIWPSGF 1307
            S P     K + EKKKND    E +V C +C    HQIC L           +   P  +
Sbjct: 1019 SMP-----KAKLEKKKNDEEIEESWVQCDKCQAWQHQICALFNGRRNDGGQAEYTCPYCY 1073

Query: 1308 VCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNH-------------PE 1354
            V D    +     +     AK L  T L +H+E R+ K L+++               P 
Sbjct: 1074 VIDVEQNERKPLLQSAVLGAKDLPRTILSDHIEQRLFKRLKQERTERARVQGTSYDEIPT 1133

Query: 1355 AGEVFVRVVASSDKTVEVKPGMKSRFVD---SGEMSESFPYRTKALFAFEEIDGVDVCFF 1411
               + VRVV+S DK +EV    KSRF++          FPY++K +  F++I+GV+VC F
Sbjct: 1134 VESLVVRVVSSVDKKLEV----KSRFLEIFREDNFPTEFPYKSKVVLLFQKIEGVEVCLF 1189

Query: 1412 GMHVQDTALIAPHQIQGCVYISYLDSIHFFRP-------RCLRTAVYHEILIGYLEYVKK 1464
            GM+VQ+      +  Q  VY+SYLDS+ +FRP         LRT VYHEILIGYLEY K 
Sbjct: 1190 GMYVQEFGSECSNPNQRRVYLSYLDSVKYFRPDIKSANGEALRTFVYHEILIGYLEYCKL 1249

Query: 1465 LVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERII----NDY 1520
              + + +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  E I+    N Y
Sbjct: 1250 RGFTSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLAMLRKAAKEGIVAETTNLY 1309

Query: 1521 KDIFKQANEDRL-TSAKELPYFEGDFWP 1547
               F Q  E R   +A  LPYF+GD+WP
Sbjct: 1310 DHFFLQTGECRAKVTAARLPYFDGDYWP 1337




 Score =  140 bits (353), Expect = 3e-31
 Identities = 75/206 (36%), Positives = 121/206 (58%), Gaps = 11/206 (5%)

Query: 1652 DPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNEC 1711
            D D +L  +  D R AFL+L +  H+++ +LRR+K S++ +L  LH      FV TCN C
Sbjct: 1477 DRDEILESEFFDTRQAFLSLCQGNHYQYDTLRRAKHSSMMVLYHLHNPTAPAFVTTCNVC 1536

Query: 1712 KHHVET--RWHCTVCEDYDLCINCYNTK---SHTHKMVKWGLGLDDEGSSQGEPQSKSPQ 1766
               +E+   W C VC DYD+C  CY  +   +H HK+      L D+ +     Q+K  +
Sbjct: 1537 HLDIESGLGWRCEVCPDYDVCNACYKKEGCINHPHKLTTHP-SLADQNA-----QNKEAR 1590

Query: 1767 ESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIAL 1826
            + R L +++ +  LVHA QCR+  C  P+C+K+K + +H   CK + +GGC +CK++  L
Sbjct: 1591 QLRVLQLRKMLDLLVHASQCRSPVCLYPNCRKVKGLFRHGLRCKVRASGGCVLCKKMWYL 1650

Query: 1827 CCYHAKHCQENKCPVPFCLNIKHNVR 1852
               HA+ C+E++C VP C ++K ++R
Sbjct: 1651 LQLHARACKESECDVPRCGDLKEHLR 1676




 Score = 57.0 bits (136), Expect = 5e-06
 Identities = 49/186 (26%), Positives = 86/186 (46%), Gaps = 22/186 (11%)

Query: 289 ATGVNPQLASKQSMVNSLPAFPTDIKNTSV------TTVPNMSQLQTSVGIVPTQAIATG 342
           ++G + Q   +Q +     A P ++   SV      +T+     LQ S+G   T      
Sbjct: 578 SSGKHIQEDFRQRITGMDEAQPNNLTEGSVIGQNHTSTISESHNLQNSIG---TTCRYGN 634

Query: 343 PTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKA 402
            + DP K K  Q+ L+ L HA  C+      G    C   +C T++ + +HM +C  P+ 
Sbjct: 635 VSHDP-KFKNQQRWLLFLRHARSCK---PPGGR---CQDQNCVTVQKLWSHMDNCADPQ- 686

Query: 403 CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAG 462
           C    C  ++ +I H+KNC    CPVC+P+K    + N + +     + ++N   +VG+ 
Sbjct: 687 CLYPRCRHTKALIGHYKNCKDPRCPVCVPVKTYQQQANVRAL-----ARLKNESSAVGSV 741

Query: 463 QQNATS 468
            ++  S
Sbjct: 742 NRSVVS 747



>gi|18405622|ref|NP_564706.1| CREB-binding protein -related [Arabidopsis thaliana]
          Length = 1456

 Score =  197 bits (501), Expect = 2e-48
 Identities = 133/359 (37%), Positives = 188/359 (52%), Gaps = 48/359 (13%)

Query: 1222 IPRDAAYYSY---QNRYHFCGKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDP 1278
            I ++A +YS    ++R++ C  C+ E + + V L        T+I K + +KKKND   P
Sbjct: 748  IKKNALHYSIAVGESRHYVCAPCYNEAREKLVFLDG------TSIPKTRLQKKKNDEQVP 801

Query: 1279 EPFVDCKECGRKMHQICVL---HYDIIWPSGFVCDNCLKKTGRPRKENKF------SAKR 1329
            E +V C +C    H IC L     +    + + C +C  +    R+           A  
Sbjct: 802  EGWVQCDKCEAWQHIICALFNSRRNHGESTKYTCPSCYIQEVEQRERRPLPLSAVPGATS 861

Query: 1330 LQTTRLGNHLEDRVNKFLRRQNH-------------PEAGEVFVRVVASSDKTVEVKPGM 1376
            L  T L  HLE+R+ K L+ +               P A  + VRVVAS DK +EVK   
Sbjct: 862  LPVTSLSKHLEERLFKKLKEERQERARLQGKTYEEVPGAESLTVRVVASVDKVLEVKERF 921

Query: 1377 KSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQD--TALIAPHQIQGCVYISY 1434
               F +    SE FPY++KA+F F++I+ V+VC FGM VQ+  T    P++ +    +S 
Sbjct: 922  LELFREENYPSE-FPYKSKAIFLFQKIENVEVCLFGMFVQEFGTDSGPPNERRTFRTVS- 979

Query: 1435 LDSIHFFRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKI 1494
                       LRT VYHEILIGYL+Y KK  + + +IWACPP +GDDYI +CHP  QK 
Sbjct: 980  --------GEALRTFVYHEILIGYLDYCKKRGFTSCYIWACPPLKGDDYILYCHPEIQKT 1031

Query: 1495 PKPKRLQEWYKKMLDKAFAERII----NDYKDIFKQANEDRL-TSAKELPYFEGDFWPN 1548
            PK  +L+EWY  ML KA  E ++    N Y   F Q+ E R   +A  LPYF+GD+WP+
Sbjct: 1032 PKTDKLREWYLAMLRKASKEDVVVECTNLYNHFFVQSGECRANVTAARLPYFDGDYWPS 1090




 Score =  119 bits (298), Expect = 8e-25
 Identities = 74/237 (31%), Positives = 116/237 (48%), Gaps = 16/237 (6%)

Query: 1616 NDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDK 1675
            N ++ + +   +K K   F + +   P       I D D  L  +    R AFL L +  
Sbjct: 1199 NRINIERHPINQKEKHALFPVAIKDVPT-----KIEDKDNNLESEFFHNRQAFLNLCQGN 1253

Query: 1676 HWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETR--WHCTVCEDYDLCINC 1733
            ++++ +LRR+K S++ +L  LH      F   C  C+  VE    WHC VC  YD+C  C
Sbjct: 1254 NYQYETLRRAKHSSMMILYHLHNPTAPAFATVCTICQQEVENSQGWHCEVCPGYDVCSAC 1313

Query: 1734 YNTKS--HTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANC 1791
            Y+  S  H+HK+       D     Q    S+S Q    + +++  + LVHA  CR+  C
Sbjct: 1314 YSKDSINHSHKLTSRSSSTDSTVVQQNGQASQSYQ----VKLEKLKKLLVHAATCRSTQC 1369

Query: 1792 SLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIK 1848
                C+K K + +H   C   T G CP+CK L +L   HA++C+++KC VP C  ++
Sbjct: 1370 QYQGCRKSKMLFRHCIDC---TTGDCPICKGLWSLLKLHARNCRDSKCTVPKCSGLR 1423



>gi|5042442|gb|AAD38279.1|AC007789_5 putative CREB-binding protein [Oryza sativa (japonica
            cultivar-group)]
          Length = 994

 Score =  192 bits (487), Expect = 1e-46
 Identities = 125/361 (34%), Positives = 188/361 (52%), Gaps = 55/361 (15%)

Query: 1237 FCGKCFTEIQGE-----NVTLGDDPSQ-----PQTTISKDQFEKK---KNDTLDPEPFVD 1283
            FC  CF  I         V  G+D S         + +K +++K+        + E +V 
Sbjct: 438  FCALCFKIINSTGSYYVEVENGNDKSSICGRCHHLSSAKAKYQKRFSYAETDAEAEWWVQ 497

Query: 1284 CKECGRKMHQICVL-HYDIIWPSG-FVCDNCLKKTGRPRKENK----------FSAKRLQ 1331
            C +C    HQIC L +  I+ P   + C  C  K     K+N+            A+ L 
Sbjct: 498  CDKCKAWQHQICALFNPKIVDPEAEYTCAKCFLK----EKDNEDVDSLEPSTILGARELP 553

Query: 1332 TTRLGNHLEDRVNKFL---RRQNHPEAGE----------VFVRVVASSDKTVEVKPGMKS 1378
             TRL +H+E R+++ L   R+Q    +G+          + VRVV+S+D+T++V+P  K 
Sbjct: 554  RTRLSDHIEQRLSERLVQERQQRAIASGKSVDEVPGVEGLTVRVVSSADRTLQVQPRFKD 613

Query: 1379 RFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSI 1438
             F    +    FPY++KA+  F++ +GVDVC F M+VQ+     P   Q  VY++Y+DS+
Sbjct: 614  -FFKKEQYPGEFPYKSKAILLFQKNEGVDVCLFAMYVQEYGSACPSPNQRHVYLAYIDSV 672

Query: 1439 HFFRP-------RCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPD 1491
             +FRP         LRT VYHEILIGYL++ KK  +V+  IW CP ++ DDY+ +CHP  
Sbjct: 673  KYFRPEIKSASGEALRTFVYHEILIGYLDFCKKRGFVSCSIWTCPSTKRDDYVLYCHPTI 732

Query: 1492 QKIPKPKRLQEWYKKMLDKAFAERII---NDYKDIFKQANEDRLT--SAKELPYFEGDFW 1546
            QK+PK  +L+ WY+ ++ KA  E ++   N   D F Q   +  T  SA  LPY + DFW
Sbjct: 733  QKMPKSDKLRSWYQNLVKKAVKEGVVVERNTLYDFFLQPTNECKTNISAAWLPYCDNDFW 792

Query: 1547 P 1547
            P
Sbjct: 793  P 793



>gi|13486836|dbj|BAB40067.1| putative CREB-binding protein [Oryza sativa (japonica
            cultivar-group)]
          Length = 936

 Score =  191 bits (486), Expect = 1e-46
 Identities = 125/361 (34%), Positives = 188/361 (52%), Gaps = 55/361 (15%)

Query: 1237 FCGKCFTEIQGE-----NVTLGDDPSQ-----PQTTISKDQFEKK---KNDTLDPEPFVD 1283
            FC  CF  I         V  G+D S         + +K +++K+        + E +V 
Sbjct: 380  FCALCFKIINSTGSYYVEVENGNDKSSICGRCHHLSSAKAKYQKRFSYAETDAEAEWWVQ 439

Query: 1284 CKECGRKMHQICVL-HYDIIWPSG-FVCDNCLKKTGRPRKENK----------FSAKRLQ 1331
            C +C    HQIC L +  I+ P   + C  C  K     K+N+            A+ L 
Sbjct: 440  CDKCKAWQHQICALFNPKIVDPEAEYTCAKCFLK----EKDNEDVDSLEPSTILGARELP 495

Query: 1332 TTRLGNHLEDRVNKFL---RRQNHPEAGE----------VFVRVVASSDKTVEVKPGMKS 1378
             TRL +H+E R+++ L   R+Q    +G+          + VRVV+S+D+T++V+P  K 
Sbjct: 496  RTRLSDHIEQRLSERLVQERQQRAIASGKSVDEVPGVEGLTVRVVSSADRTLQVQPRFKD 555

Query: 1379 RFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSI 1438
             F    +    FPY++KA+  F++ +GVDVC F M+VQ+     P   Q  VY++Y+DS+
Sbjct: 556  -FFKKEQYPGEFPYKSKAILLFQKNEGVDVCLFAMYVQEYGSACPSPNQRHVYLAYIDSV 614

Query: 1439 HFFRP-------RCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPD 1491
             +FRP         LRT VYHEILIGYL++ KK  +V+  IW CP ++ DDY+ +CHP  
Sbjct: 615  KYFRPEIKSASGEALRTFVYHEILIGYLDFCKKRGFVSCSIWTCPSTKRDDYVLYCHPTI 674

Query: 1492 QKIPKPKRLQEWYKKMLDKAFAERII---NDYKDIFKQANEDRLT--SAKELPYFEGDFW 1546
            QK+PK  +L+ WY+ ++ KA  E ++   N   D F Q   +  T  SA  LPY + DFW
Sbjct: 675  QKMPKSDKLRSWYQNLVKKAVKEGVVVERNTLYDFFLQPTNECKTNISAAWLPYCDNDFW 734

Query: 1547 P 1547
            P
Sbjct: 735  P 735



>gi|18408717|ref|NP_564891.1| hypothetical protein [Arabidopsis thaliana]
 gi|25404951|pir||B96696 protein F1N21.4 [imported] - Arabidopsis thaliana
 gi|9828615|gb|AAG00238.1|AC002130_3 F1N21.4 [Arabidopsis thaliana]
          Length = 1357

 Score =  189 bits (481), Expect = 4e-46
 Identities = 128/383 (33%), Positives = 184/383 (48%), Gaps = 53/383 (13%)

Query: 1207 FSPQTLCCYGKQLCTIPRDAAYYSY--------QNRYHFCGKCFTEIQGENVTLGDDPSQ 1258
            F PQ L C    LC+   D   + Y          ++  C  C +  + +    G     
Sbjct: 655  FPPQPLYCL---LCSRRIDDRSFYYTPGEEELSNAQHQICSPCHSRCKTKFPLCG----- 706

Query: 1259 PQTTISKDQFEKKKN-DTLDPEPFVDCKECGRKMHQICVLH---YDIIWPSGFVCDNCLK 1314
                I K +  K+ N D  D E +V C+ C +  HQIC L+    D    + ++C  CL 
Sbjct: 707  --VFIDKHKMLKRSNFDNADTEEWVQCESCEKWQHQICGLYNKLKDEDKTAEYICPTCLL 764

Query: 1315 KTGRPRKENKF------SAKRLQTTRLGNHLEDRVNKFLRRQNH-------------PEA 1355
            +  +              AK L  T L   LE R+ K L+ + +             PE 
Sbjct: 765  EECQSINNMALVDYTDSGAKDLPETVLSYFLEQRLFKRLKEERYQTAKATGKSINDVPEP 824

Query: 1356 GEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHV 1415
              + +RVV S+D+T+ V     S        SE FPYR+K +  F+++ GVD+C F + V
Sbjct: 825  EGLTLRVVFSADRTLTVNKQFASLLHKENFPSE-FPYRSKVILLFQKVHGVDICIFALFV 883

Query: 1416 QDTALIAPHQIQGCVYISYLDSIHFFRP-------RCLRTAVYHEILIGYLEYVKKLVYV 1468
            Q+         Q   YI YLDS+ +F+P         LRT VYHE+LIGYLEY K   + 
Sbjct: 884  QEFGSECSQPNQRSTYIFYLDSVKYFKPERVTFAGEALRTFVYHEVLIGYLEYCKLRGFT 943

Query: 1469 TAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERI---INDYKDIFK 1525
            T++IWACPP  G DYI + HP  Q+ P  K+L++WY  ML KA  +R+   + +  D F 
Sbjct: 944  TSYIWACPPKIGQDYIMYSHPKTQQTPDTKKLRKWYVSMLQKAAEQRVVMNVTNLYDRFF 1003

Query: 1526 QANEDRLTSAKELPYFEGDFWPN 1548
             + E+ +T+A+ LPYFEG FW N
Sbjct: 1004 DSTEEYMTAAR-LPYFEGSFWSN 1025




 Score = 96.7 bits (239), Expect = 5e-18
 Identities = 69/236 (29%), Positives = 108/236 (45%), Gaps = 26/236 (11%)

Query: 1620 QKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEF 1679
            + +Y  M+K K     + ++ G + ST     D D +   D+ + R AFL  ++  ++ F
Sbjct: 1136 EHIYKRMDKEKHQLSKVQVN-GVLFSTTE---DNDIIQENDMFESRQAFLAFSQKHNYNF 1191

Query: 1680 SSLRRSKWSTLCMLVELHTQ-----GQDRFVYTCNECKHHVETRWH--CTVCEDYDLCIN 1732
             +LR +K S++ +L  LHT       Q+    TC  CK  V T  +  C +C DY  C  
Sbjct: 1192 HTLRHAKHSSMMILHHLHTSNKHHCSQNSSSLTCTACKKDVSTTIYFPCLLCPDYRACTG 1251

Query: 1733 CYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRN---A 1789
            CY TK+ T + +     L           S +   SR + +   + ++ HA  C++    
Sbjct: 1252 CY-TKNRTLRHLHIFPTL----------PSANRAPSRTVMVLEILNAISHALLCQHKTTK 1300

Query: 1790 NCSLPSCQKMKRVVQHTKGCK-RKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFC 1844
            +CS P C ++K +  H   CK RK    C  C +L      H  HCQ+  CPVP C
Sbjct: 1301 SCSYPKCHEVKALFTHNVQCKIRKKGTRCNTCYKLWQTIRIHVYHCQDLNCPVPQC 1356



>gi|11514507|pdb|1F81|A Chain A, Solution Structure Of The Taz2 Domain Of The Transcriptional
            Adaptor Protein Cbp
          Length = 88

 Score =  187 bits (474), Expect = 3e-45
 Identities = 86/86 (100%), Positives = 86/86 (100%)

Query: 1764 SPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQL 1823
            SPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQL
Sbjct: 2    SPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQL 61

Query: 1824 IALCCYHAKHCQENKCPVPFCLNIKH 1849
            IALCCYHAKHCQENKCPVPFCLNIKH
Sbjct: 62   IALCCYHAKHCQENKCPVPFCLNIKH 87




 Score = 40.8 bits (94), Expect = 0.31
 Identities = 33/94 (35%), Positives = 49/94 (52%), Gaps = 18/94 (19%)

Query: 348 EKRKL-IQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQVA 406
           E R+L IQ+ +  L+HA +C+    AN     CSLP C+ MK V+ H   C+        
Sbjct: 5   ESRRLSIQRCIQSLVHACQCR---NAN-----CSLPSCQKMKRVVQHTKGCKRKTN---G 53

Query: 407 HCASSRQIIS----HWKNCTRHDCPV--CLPLKN 434
            C   +Q+I+    H K+C  + CPV  CL +K+
Sbjct: 54  GCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKH 87



>gi|20664319|pdb|1L8C|A Chain A, Structural Basis For Hif-1alphaCBP RECOGNITION IN THE
           Cellular Hypoxic Response
          Length = 95

 Score =  178 bits (451), Expect = 1e-42
 Identities = 94/95 (98%), Positives = 94/95 (98%)

Query: 345 ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQ 404
           ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQA KACQ
Sbjct: 1   ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQ 60

Query: 405 VAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKR 439
           VAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKR
Sbjct: 61  VAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKR 95



>gi|4139873|pdb|1KDX|A Chain A, Kix Domain Of Mouse Cbp (Creb Binding Protein) In Complex
           With Phosphorylated Kinase Inducible Domain (Pkid) Of
           Rat Creb (Cyclic Amp Response Element Binding Protein),
           Nmr 17 Structures
          Length = 81

 Score =  175 bits (444), Expect = 9e-42
 Identities = 80/80 (100%), Positives = 80/80 (100%)

Query: 587 VRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSR 646
           VRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSR
Sbjct: 2   VRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSR 61

Query: 647 DEYYHLLAEKIYKIQKELEE 666
           DEYYHLLAEKIYKIQKELEE
Sbjct: 62  DEYYHLLAEKIYKIQKELEE 81



>gi|6056385|gb|AAF02849.1|AC009894_20 Unknown protein [Arabidopsis thaliana]
          Length = 1209

 Score =  171 bits (432), Expect = 2e-40
 Identities = 122/367 (33%), Positives = 175/367 (47%), Gaps = 73/367 (19%)

Query: 1222 IPRDAAYYSY---QNRYHFCGKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDP 1278
            I ++A +YS    ++R++ C  C+ E + + V L        T+I K + +KKKND   P
Sbjct: 748  IKKNALHYSIAVGESRHYVCAPCYNEAREKLVFLDG------TSIPKTRLQKKKNDEQVP 801

Query: 1279 EPFVDCKECGRKMHQICVL---HYDIIWPSGFVCDNCLKKTGRPRKENKF------SAKR 1329
            E +V C +C    H IC L     +    + + C +C  +    R+           A  
Sbjct: 802  EGWVQCDKCEAWQHIICALFNSRRNHGESTKYTCPSCYIQEVEQRERRPLPLSAVPGATS 861

Query: 1330 LQTTRLGNHLEDRVNKFLRRQNH-----------------------PEAGEVFVRVVASS 1366
            L  T L  HLE+R+ K L+ +                         P A  + VRVVAS 
Sbjct: 862  LPVTSLSKHLEERLFKKLKEERQERARLQGKTYEEVISNSLRLSTVPGAESLTVRVVASV 921

Query: 1367 DKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQI 1426
            DK +EVK      F +    SE FPY++KA+F F++I+ V+VC FGM VQ+         
Sbjct: 922  DKVLEVKERFLELFREENYPSE-FPYKSKAIFLFQKIENVEVCLFGMFVQEFG------- 973

Query: 1427 QGCVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFH 1486
                                 +   +E  IGYL+Y KK  + + +IWACPP +GDDYI +
Sbjct: 974  -------------------TDSGPPNERRIGYLDYCKKRGFTSCYIWACPPLKGDDYILY 1014

Query: 1487 CHPPDQKIPKPKRLQEWYKKMLDKAFAERII----NDYKDIFKQANEDRL-TSAKELPYF 1541
            CHP  QK PK  +L+EWY  ML KA  E ++    N Y   F Q+ E R   +A  LPYF
Sbjct: 1015 CHPEIQKTPKTDKLREWYLAMLRKASKEDVVVECTNLYNHFFVQSGECRANVTAARLPYF 1074

Query: 1542 EGDFWPN 1548
            +GD+WP+
Sbjct: 1075 DGDYWPS 1081



>gi|1888538|gb|AAC51339.1| CREB-binding protein [Homo sapiens]
          Length = 190

 Score =  171 bits (432), Expect = 2e-40
 Identities = 111/190 (58%), Positives = 115/190 (60%)

Query: 2252 HLPIQGSSXXXXXXXXXXXXXXXXXXXXADSTPNXXXXXXXXXXXXXXXXXXXGSPGQPN 2311
            HLP+QGSS                    ADSTPN                   GSPGQPN
Sbjct: 1    HLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPN 60

Query: 2312 PMSPQQHMLSGQPQASHLPGQQIATSLSNQVXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2371
            PMSPQQHMLSGQPQASHLPGQQIATSLSNQV                             
Sbjct: 61   PMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPS 120

Query: 2372 XXXXXXXTGTPHPGLAVTMASSMDQGHLGNPEQSAMLPQLNTPNRSALSSELSLVGDTTG 2431
                   TG+PHPGLAVTMASS+DQGHLGNPEQSAMLPQLNTP+RSALSSELSLVGDTTG
Sbjct: 121  PHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTG 180

Query: 2432 DTLEKFVEGL 2441
            DTLEKFVEGL
Sbjct: 181  DTLEKFVEGL 190



>gi|20664269|pdb|1L3E|B Chain B, Nmr Structures Of The Hif-1alpha CtadP300 CH1 COMPLEX
 gi|33357860|pdb|1P4Q|B Chain B, Solution Structure Of The Cited2 Transactivation Domain In
           Complex With The P300 Ch1 Domain
          Length = 101

 Score =  170 bits (431), Expect = 3e-40
 Identities = 89/95 (93%), Positives = 92/95 (96%)

Query: 344 TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKAC 403
           TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+ K+C
Sbjct: 7   TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSC 66

Query: 404 QVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDK 438
           QVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DK
Sbjct: 67  QVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDK 101



>gi|8778322|gb|AAF79331.1|AC002304_24 F14J16.27 [Arabidopsis thaliana]
          Length = 1550

 Score =  159 bits (403), Expect = 5e-37
 Identities = 133/427 (31%), Positives = 188/427 (44%), Gaps = 116/427 (27%)

Query: 1222 IPRDAAYYSY---QNRYHFCGKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDP 1278
            I ++A +YS    ++R++ C  C+ E + + V L        T+I K + +KKKND   P
Sbjct: 748  IKKNALHYSIAVGESRHYVCAPCYNEAREKLVFLDG------TSIPKTRLQKKKNDEQVP 801

Query: 1279 E-----------------------------------PFVDCKECGRKMHQICVL---HYD 1300
            E                                    +V C +C    H IC L     +
Sbjct: 802  EGVCMPHDFGNLFLPLFFFFFVFFFCVCLNQTNGFLQWVQCDKCEAWQHIICALFNSRRN 861

Query: 1301 IIWPSGFVCDNCLKKTGRPRKENKF------SAKRLQTTRLGNHLEDRVNKFLRRQNH-- 1352
                + + C +C  +    R+           A  L  T L  HLE+R+ K L+ +    
Sbjct: 862  HGESTKYTCPSCYIQEVEQRERRPLPLSAVPGATSLPVTSLSKHLEERLFKKLKEERQER 921

Query: 1353 -----------PEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTK---ALF 1398
                       P A  + VRVVAS DK +EVK      F +    SE FPY++K   A+F
Sbjct: 922  ARLQGKTYEEVPGAESLTVRVVASVDKVLEVKERFLELFREENYPSE-FPYKSKVAMAIF 980

Query: 1399 AFEEIDGVDVCFFGMHVQD--TALIAPHQIQGCVYISYLDSIHFFRPRCLRTAVYHEIL- 1455
             F++I+ V+VC FGM VQ+  T    P++ +    +S            LRT VYHEIL 
Sbjct: 981  LFQKIENVEVCLFGMFVQEFGTDSGPPNERRTFRTVS---------GEALRTFVYHEILV 1031

Query: 1456 -----------------------------IGYLEYVKKLVYVTAHIWACPPSEGDDYIFH 1486
                                         IGYL+Y KK  + + +IWACPP +GDDYI +
Sbjct: 1032 SRFISNPIFFRFRVLLHEYMKLIIVTNLQIGYLDYCKKRGFTSCYIWACPPLKGDDYILY 1091

Query: 1487 CHPPDQKIPKPKRLQEWYKKMLDKAFAERII----NDYKDIFKQANEDRL-TSAKELPYF 1541
            CHP  QK PK  +L+EWY  ML KA  E ++    N Y   F Q+ E R   +A  LPYF
Sbjct: 1092 CHPEIQKTPKTDKLREWYLAMLRKASKEDVVVECTNLYNHFFVQSGECRANVTAARLPYF 1151

Query: 1542 EGDFWPN 1548
            +GD+WP+
Sbjct: 1152 DGDYWPS 1158




 Score =  119 bits (297), Expect = 1e-24
 Identities = 69/203 (33%), Positives = 104/203 (51%), Gaps = 11/203 (5%)

Query: 1650 IVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCN 1709
            I D D  L  +    R AFL L +  ++++ +LRR+K S++ +L  LH      F   C 
Sbjct: 1322 IEDKDNNLESEFFHNRQAFLNLCQGNNYQYETLRRAKHSSMMILYHLHNPTAPAFATVCT 1381

Query: 1710 ECKHHVETR--WHCTVCEDYDLCINCYNTKS--HTHKMVKWGLGLDDEGSSQGEPQSKSP 1765
             C+  VE    WHC VC  YD+C  CY+  S  H+HK+       D     Q    S+S 
Sbjct: 1382 ICQQEVENSQGWHCEVCPGYDVCSACYSKDSINHSHKLTSRSSSTDSTVVQQNGQASQSY 1441

Query: 1766 QESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIA 1825
            Q    + +++  + LVHA  CR+  C    C+K K + +H   C   T G CP+CK L +
Sbjct: 1442 Q----VKLEKLKKLLVHAATCRSTQCQYQGCRKSKMLFRHCIDC---TTGDCPICKGLWS 1494

Query: 1826 LCCYHAKHCQENKCPVPFCLNIK 1848
            L   HA++C+++KC VP C  ++
Sbjct: 1495 LLKLHARNCRDSKCTVPKCSGLR 1517



>gi|17553334|ref|NP_499197.1| CREB-binding protein like family member (22.2 kD) (3L5)
           [Caenorhabditis elegans]
 gi|542476|pir||S42836 F40F12.7 protein - Caenorhabditis elegans
 gi|3877001|emb|CAA82938.1| Hypothetical protein F40F12.7 [Caenorhabditis elegans]
          Length = 199

 Score =  132 bits (332), Expect = 8e-29
 Identities = 63/101 (62%), Positives = 71/101 (70%), Gaps = 9/101 (8%)

Query: 346 DPEKRKLIQQQLVLLLHAHKCQRREQANGEV---------RACSLPHCRTMKNVLNHMTH 396
           DP KRKLIQQQ VLLLHAHKC +RE+ N E           AC+LPHC TMK VL HMT+
Sbjct: 7   DPVKRKLIQQQFVLLLHAHKCSQREKENNEFAARNQLLPHAACTLPHCSTMKEVLIHMTN 66

Query: 397 CQAPKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASD 437
           C   + C  AHCASSRQII+HWK+C+R DCPVC PLK   D
Sbjct: 67  CNVGRLCHFAHCASSRQIIAHWKDCSREDCPVCKPLKGIQD 107



>gi|19173764|ref|NP_596894.1| E1A binding protein p300 [Rattus norvegicus]
 gi|15076626|dbj|BAB62425.1| E1A-binding protein [Rattus norvegicus]
          Length = 353

 Score =  125 bits (315), Expect = 8e-27
 Identities = 137/386 (35%), Positives = 177/386 (45%), Gaps = 52/386 (13%)

Query: 1   MAENLLD-GPPNPKRAK--LSSPGFSANDNTDFGSLFDLENDLPDELIP---------XX 48
           MAEN+++ GPP+ KR K    +   SA+D TDFGSLFDLE+DLPDELI            
Sbjct: 1   MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60

Query: 49  XXXXXXXXXXVPDAASKHKQLSELLRXXXXXXXXXXXXXXXASSPVXXXXXXXXXXXPNS 108
                     V DAASKHKQLSELLR                                NS
Sbjct: 61  ISQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQ--------VMASQAQQNS 112

Query: 109 TNMASLGAMGKSPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATS 168
             ++ + +M KSP+ Q   ++PN+      +SGP    +Q+         G++ S     
Sbjct: 113 PGLSLINSMVKSPMAQTGLTSPNM---GMGSSGPNQGPTQS-------TAGMMNSPVNQP 162

Query: 169 QTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLXXXXXXXXXXXXXXXX 228
             G    MNA  N   PG+L + +G  +M        QVMNGS+                
Sbjct: 163 AMGMNTGMNAGMN---PGMLAAGNGQGIMPN------QVMNGSI---GAGRGRPNMQYPN 210

Query: 229 XXXXXTSSVLAETLTQVSPQMAGHAGLNTAQAXXXXXXXXXXXXSPFGQPFSQTGGQQMG 288
                  S+L E L Q SPQM G  GL   Q+            +P+G P++Q  GQQ+G
Sbjct: 211 AGMGNAGSLLTEPLQQGSPQMGGQPGLRGPQS---HKMGMMSNPTPYGSPYTQNSGQQIG 267

Query: 289 ATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGP----- 343
           A+G+  Q+ +K  + N+L  F  D K  +   +PNM Q  T     P       P     
Sbjct: 268 ASGLGLQIQTKTVLPNNLSPFAMDKKAVTGGGMPNMGQQPTPSVQQPGLVNPVAPGMGSG 327

Query: 344 --TADPEKRKLIQQQLVLLLHAHKCQ 367
             TADPEKRKLIQQQLVLLLHAHKCQ
Sbjct: 328 AHTADPEKRKLIQQQLVLLLHAHKCQ 353



>gi|14794966|gb|AAK73519.1| HAC4 [Arabidopsis thaliana]
          Length = 413

 Score =  124 bits (311), Expect = 3e-26
 Identities = 74/237 (31%), Positives = 116/237 (48%), Gaps = 16/237 (6%)

Query: 1616 NDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDK 1675
            N ++ + +   +K K   F + +   P       I D D  L  +    R AFL L +  
Sbjct: 156  NRINIERHPINQKEKHALFPVAIKDVPT-----KIEDKDNNLESEFFHNRQAFLNLCQGN 210

Query: 1676 HWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETR--WHCTVCEDYDLCINC 1733
            ++++ +LRR+K S++ +L  LH      F   C  C+  VE    WHC VC  YD+C  C
Sbjct: 211  NYQYETLRRAKHSSMMILYHLHNPTAPAFATVCTICQQEVENSQGWHCEVCPGYDVCSAC 270

Query: 1734 YNTKS--HTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANC 1791
            Y+  S  H+HK+       D     Q    S+S Q    + +++  + LVHA  CR+  C
Sbjct: 271  YSKDSINHSHKLTSRSSSTDSTVVQQNGQASQSYQ----VKLEKLKKLLVHAATCRSTQC 326

Query: 1792 SLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIK 1848
                C+K K + +H   C   T G CP+CK L +L   HA++C+++KC VP C  ++
Sbjct: 327  QYQGCRKSKMLFRHCIDC---TTGDCPICKGLWSLLKLHARNCRDSKCTVPKCSGLR 380



>gi|21105785|gb|AAM34790.1|AF512560_2 HAC4 [Arabidopsis thaliana]
          Length = 385

 Score =  123 bits (308), Expect = 5e-26
 Identities = 74/237 (31%), Positives = 116/237 (48%), Gaps = 16/237 (6%)

Query: 1616 NDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDK 1675
            N ++ + +   +K K   F + +   P       I D D  L  +    R AFL L +  
Sbjct: 128  NRINIERHPINQKEKHALFPVAIKDVPT-----KIEDKDNNLESEFFHNRQAFLNLCQGN 182

Query: 1676 HWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETR--WHCTVCEDYDLCINC 1733
            ++++ +LRR+K S++ +L  LH      F   C  C+  VE    WHC VC  YD+C  C
Sbjct: 183  NYQYETLRRAKHSSMMILYHLHNPTAPAFATVCTICQQEVENSQGWHCEVCPGYDVCSAC 242

Query: 1734 YNTKS--HTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANC 1791
            Y+  S  H+HK+       D     Q    S+S Q    + +++  + LVHA  CR+  C
Sbjct: 243  YSKDSINHSHKLTSRSSSTDSTVVQQNGQASQSYQ----VKLEKLKKLLVHAATCRSTQC 298

Query: 1792 SLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIK 1848
                C+K K + +H   C   T G CP+CK L +L   HA++C+++KC VP C  ++
Sbjct: 299  QYQGCRKSKMLFRHCIDC---TTGDCPICKGLWSLLKLHARNCRDSKCTVPKCSGLR 352



>gi|7494646|pir||T37269 hypothetical protein - Caenorhabditis elegans (fragment)
 gi|2665395|dbj|BAA23766.1| unnamed protein product [Caenorhabditis elegans]
          Length = 118

 Score =  112 bits (280), Expect = 1e-22
 Identities = 65/101 (64%), Positives = 72/101 (71%), Gaps = 9/101 (8%)

Query: 346 DPEKRKLIQQQLVLLLHAHKCQRREQANGEV---------RACSLPHCRTMKNVLNHMTH 396
           DPEKRKLIQQQLVLLLHAHKC +RE+ N +           AC+LPHC TMK VL HMT 
Sbjct: 3   DPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTS 62

Query: 397 CQAPKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASD 437
           C   + C  AHCASSRQII+HWKNC+R DCPVC PLK   D
Sbjct: 63  CNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCKPLKRIQD 103





  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF
    Posted date:  Sep 11, 2003  1:15 AM
  Number of letters in database: 490,308,901
  Number of sequences in database:  1,522,899
  
Lambda     K      H
   0.314    0.130    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 200,572,572
Number of Sequences: 1522899
Number of extensions: 7967760
Number of successful extensions: 23262
Number of sequences better than  1.0: 93
Number of HSP's better than  1.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 22616
Number of HSP's gapped (non-prelim): 494
length of query: 2441
length of database: 490,308,901
effective HSP length: 141
effective length of query: 2300
effective length of database: 275,580,142
effective search space: 633834326600
effective search space used: 633834326600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 90 (39.3 bits)