RID=1063375501-11215-755243.BLASTQ3, Aplysia_CBP gi|21307831|gb|AAL54859_1| CREB-binding protein [Aplysia californica] BLASTP 2.2.6 [Apr-09-2003]

RID: 1063375501-11215-755243.BLASTQ3

Query= Aplysia_CBP gi|21307831|gb|AAL54859_1| CREB-binding protein [Aplysia californica] (2245 letters)

Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 1,522,899 sequences; 490,308,901 total letters

Distribution of 174 Blast Hits on the Query Sequence




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21307831|gb|AAL54859.1|  CREB-binding protein [Aplysia ca...  2962   0.0  
gi|7511830|pir||T13828  CREB-binding protein homolog - fruit...  1062   0.0  
gi|24640865|ref|NP_524642.2|  nejire CG15319-PB [Drosophila ...  1057   0.0  
gi|4758056|ref|NP_004371.1|  CREB binding protein [Homo sapi...  1038   0.0  
gi|4321116|gb|AAC51331.2|  CREB-binding protein [Homo sapiens]   1038   0.0  
gi|19547885|gb|AAL87531.1|  CREB-binding protein [Mus muscul...  1032   0.0  
gi|4557557|ref|NP_001420.1|  E1A binding protein p300; E1A-b...  1022   0.0  
gi|631119|pir||S39162  transcription coactivator CREB-bindin...  1004   0.0  
gi|737920|prf||1923401A  protein CBP                             1000   0.0  
gi|1345703|sp|P45481|CBP_MOUSE  CREB-binding protein >gi|481...   999   0.0  
gi|27663074|ref|XP_235502.1|  similar to E1A-associated prot...   994   0.0  
gi|27666550|ref|XP_235770.1|  similar to E1A-associated prot...   950   0.0  
gi|31753089|gb|AAH53889.1|  Unknown (protein for IMAGE:61513...   712   0.0  
gi|2133462|pir||S60123  hypothetical protein R10E11.1 - Caen...   545   e-153
gi|17552708|ref|NP_499161.1|  CBP/p300 homolog (cbp-1) [Caen...   544   e-153
gi|17552710|ref|NP_499160.1|  CBP/p300 homolog (cbp-1) [Caen...   544   e-153
gi|1888540|gb|AAC51340.1|  CREB-binding protein [Homo sapiens]    374   e-101
gi|28486618|ref|XP_128116.2|  similar to E1A-associated prot...   324   1e-86
gi|3168627|gb|AAC17736.1|  CBP [Homo sapiens]                     318   6e-85
gi|547239|gb|AAB31182.1|  p300=transcription coactivator {N-...   286   5e-75
gi|28486616|ref|XP_283295.1|  similar to E1A-associated prot...   269   6e-70
gi|27881767|gb|AAH44677.1|  Similar to CREB binding protein ...   266   3e-69
gi|2996629|gb|AAC08447.1|  CBP [Homo sapiens]                     266   3e-69
gi|21105780|gb|AAM34788.1|AF512558_2  HAC5 [Arabidopsis thal...   245   6e-63
gi|15230656|ref|NP_187904.1|  CREB-binding protein -related ...   239   6e-61
gi|27667568|ref|XP_213219.1|  similar to CREB-binding protei...   238   1e-60
gi|7487910|pir||T01055  hypothetical protein YUP8H12R.38 - A...   236   5e-60
gi|18412221|ref|NP_565197.1|  p300/CBP acetyltransferase-rel...   233   2e-59
gi|25518555|pir||E86302  hypothetical protein F17F16.8 [impo...   224   2e-56
gi|15219327|ref|NP_173115.1|  expressed protein [Arabidopsis...   223   3e-56
gi|18405622|ref|NP_564706.1|  CREB-binding protein -related ...   204   2e-50
gi|5042442|gb|AAD38279.1|AC007789_5  putative CREB-binding p...   200   2e-49
gi|13486836|dbj|BAB40067.1|  putative CREB-binding protein [...   200   3e-49
gi|23200188|pdb|1JSP|B  Chain B, Nmr Structure Of Cbp Bromod...   199   4e-49
gi|18408717|ref|NP_564891.1|  hypothetical protein [Arabidop...   199   7e-49
gi|6056385|gb|AAF02849.1|AC009894_20  Unknown protein [Arabi...   177   2e-42
gi|8778322|gb|AAF79331.1|AC002304_24  F14J16.27 [Arabidopsis...   168   1e-39
gi|11514507|pdb|1F81|A  Chain A, Solution Structure Of The T...   145   7e-33
gi|4139873|pdb|1KDX|A  Chain A, Kix Domain Of Mouse Cbp (Cre...   143   3e-32
gi|20664269|pdb|1L3E|B  Chain B, Nmr Structures Of The Hif-1...   125   1e-26
gi|20664319|pdb|1L8C|A  Chain A, Structural Basis For Hif-1a...   124   2e-26
gi|14794966|gb|AAK73519.1|  HAC4 [Arabidopsis thaliana]           124   3e-26
gi|21105785|gb|AAM34790.1|AF512560_2  HAC4 [Arabidopsis thal...   123   4e-26
gi|17553334|ref|NP_499197.1|  CREB-binding protein like fami...   120   2e-25
gi|482238|pir||S41033  hypothetical protein K03H1.10 - Caeno...   104   2e-20
gi|17554044|ref|NP_499201.1|  CREB-binding protein like fami...   104   2e-20
gi|7494646|pir||T37269  hypothetical protein - Caenorhabditi...   103   5e-20
gi|13699186|dbj|BAB41205.1|  kinase-like protein [Oryza sativa]    96   6e-18
gi|7493489|pir||T40984  transcription factor bdf1 homolog SP...    91   3e-16
gi|29569106|gb|AAO84020.1|  global transcription factor grou...    88   2e-15
gi|17552400|ref|NP_497145.1|  CREB-binding protein like fami...    87   4e-15
gi|23664002|gb|AAN39141.1|  CREB-binding protein [Rattus nor...    87   4e-15
gi|33146482|dbj|BAC79591.1|  putative RING3 protein [Oryza s...    86   1e-14
gi|6016737|gb|AAF01563.1|AC009325_33  hypothetical protein [...    84   3e-14
gi|18395937|ref|NP_566151.1|  DNA-binding protein family [Ar...    84   3e-14
gi|15242727|ref|NP_201138.1|  DNA-binding protein family [Ar...    83   7e-14
gi|27720883|ref|XP_236438.1|  similar to WD repeat domain 11...    82   2e-13
gi|17976800|emb|CAC83118.1|  WD repeat domain 11 protein [Ho...    81   2e-13
gi|8885596|dbj|BAA97526.1|  contains similarity to kinase~ge...    81   2e-13
gi|30694987|ref|NP_199467.2|  DNA-binding protein family [Ar...    80   4e-13
gi|17976802|emb|CAC83119.1|  WD repeat domain 11 protein [Mu...    80   4e-13
gi|12007334|gb|AAG45145.1|  IRS-1 PH domain binding protein ...    80   4e-13
gi|12007336|gb|AAG45146.1|  IRS-1 PH domain binding protein ...    80   4e-13
gi|6320132|ref|NP_010213.1|  bromodomain protein, homolog of...    80   6e-13
gi|17551090|ref|NP_510006.1|  CREB-binding protein like fami...    79   9e-13
gi|20149648|ref|NP_060404.2|  pleckstrin homology domain int...    79   1e-12
gi|7020972|dbj|BAA91336.1|  unnamed protein product [Homo sa...    79   1e-12
gi|19171509|emb|CAC84085.1|  hypothetical protein [Takifugu ...    78   2e-12
gi|22761009|dbj|BAC11417.1|  unnamed protein product [Homo s...    77   4e-12
gi|9294219|dbj|BAB02121.1|  gb|AAF01563.1~gene_id:K17E12.8~s...    77   5e-12
gi|15232127|ref|NP_189362.1|  DNA-binding protein family [Ar...    77   5e-12
gi|24649631|ref|NP_732982.1|  CG31132-PA [Drosophila melanog...    76   7e-12
gi|19114532|ref|NP_593620.1|  protein with 2 bromodomains, p...    76   7e-12
gi|7485801|pir||T00472  probable RING3 protein [imported] - ...    76   7e-12
gi|17064912|gb|AAL32610.1|  Unknown protein [Arabidopsis tha...    76   9e-12
gi|30686240|ref|NP_181036.2|  RING3 protein -related [Arabid...    75   1e-11
gi|27804346|gb|AAO22237.1|  BRD4-NUT fusion oncoprotein [Hom...    75   1e-11
gi|16445438|ref|NP_387505.1|  WD repeat domain 9 isoform B; ...    75   1e-11
gi|7717364|emb|CAB90452.1|  homolog to cAMP response element...    75   1e-11
gi|23831562|sp|Q9NSI6|WDR9_HUMAN  WD-repeat protein 9 >gi|20...    75   1e-11
gi|14970564|emb|CAC44372.1|  WDR9 protein, form B [Homo sapi...    75   1e-11
gi|16445436|ref|NP_061836.2|  WD repeat domain 9 isoform A; ...    75   2e-11
gi|14970562|emb|CAC44371.1|  WDR9 protein, form A [Homo sapi...    75   2e-11
gi|6323431|ref|NP_013503.1|  Required for sporulation, possi...    75   2e-11
gi|19173489|ref|NP_597292.1|  GENERAL TRANSCRIPTION FACTOR [...    75   2e-11
gi|311664|emb|CAA79377.1|  BDF1 [Saccharomyces cerevisiae]         75   2e-11
gi|20151643|gb|AAM11181.1|  LD40380p [Drosophila melanogaster]     74   2e-11
gi|608567|gb|AAA89115.1|  Bdf1p                                    74   2e-11
gi|11358472|pir||T48600  kinase-like protein - Arabidopsis t...    74   3e-11
gi|26345416|dbj|BAC36359.1|  unnamed protein product [Mus mu...    74   3e-11
gi|18417335|ref|NP_568297.1|  DNA-binding protein family [Ar...    74   3e-11
gi|26332152|dbj|BAC29806.1|  unnamed protein product [Mus mu...    74   3e-11
gi|3184498|gb|AAC27978.1|  R31546_1 [Homo sapiens]                 74   4e-11
gi|7657218|ref|NP_055114.1|  bromodomain-containing protein ...    74   4e-11
gi|33879612|gb|AAH30158.1|  Unknown (protein for IMAGE:50869...    74   4e-11
gi|18308127|gb|AAL67834.1|AF461396_1  bromodomain-containing...    74   4e-11
gi|24640484|ref|NP_727228.1|  female sterile (1) homoeotic C...    74   5e-11
gi|33416865|gb|AAH55543.1|  Unknown (protein for IMAGE:59138...    73   5e-11
gi|8575733|gb|AAF78072.1|  bromodomain-containing FSH-like p...    73   5e-11
gi|31981064|ref|NP_075825.2|  bromodomain containing 3; brom...    73   5e-11
Alignments
>gi|21307831|gb|AAL54859.1| CREB-binding protein [Aplysia californica]
          Length = 2245

 Score = 2962 bits (7680), Expect = 0.0
 Identities = 1590/1993 (79%), Positives = 1590/1993 (79%)

Query: 1    MADHQLGPPANKKPRIGSPSLNTPSDNNEFNFGNLNFDGIVNELPDDLDGLQGTSGDGQT 60
            MADHQLGPPANKKPRIGSPSLNTPSDNNEFNFGNLNFDGIVNELPDDLDGLQGTSGDGQT
Sbjct: 1    MADHQLGPPANKKPRIGSPSLNTPSDNNEFNFGNLNFDGIVNELPDDLDGLQGTSGDGQT 60

Query: 61   PQGSQDTSMGGSLSQLLSRSTPNSQTSLPLPVNSAGGIQTSRSPXXXXXXXXXXXXXXXX 120
            PQGSQDTSMGGSLSQLLSRSTPNSQTSLPLPVNSAGGIQTSRSP                
Sbjct: 61   PQGSQDTSMGGSLSQLLSRSTPNSQTSLPLPVNSAGGIQTSRSPGMGAMMNMGMGKNPMS 120

Query: 121  XXXXXXXXXXXXXXXHMNMNDALVSSASFTISGTNAGPMGGVTNTMGMNPTMGNPQMIGS 180
                           HMNMNDALVSSASFTISGTNAGPMGGVTNTMGMNPTMGNPQMIGS
Sbjct: 121  NNLAATLANKAATSSHMNMNDALVSSASFTISGTNAGPMGGVTNTMGMNPTMGNPQMIGS 180

Query: 181  VGSLXXXXXXXXXXXXGPTSFPGNMGQMRAMQGNNVNPSTSMQVXXXXXXXXXXXXXXXX 240
            VGSL            GPTSFPGNMGQMRAMQGNNVNPSTSMQV                
Sbjct: 181  VGSLNMNQQMPNQMMNGPTSFPGNMGQMRAMQGNNVNPSTSMQVPQTGMMQSPGMPQMQG 240

Query: 241  XXXXXXXXXXXXXXXXXXXIRXXXXXXXXXXXXRQAAGEPDKSKLIQQQLVLLLHAHKCQ 300
                               IR            RQAAGEPDKSKLIQQQLVLLLHAHKCQ
Sbjct: 241  HQGMPGHPNMNMPQNPPQNIRPGQPTGSGTSGPRQAAGEPDKSKLIQQQLVLLLHAHKCQ 300

Query: 301  RREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAHCASSRQIITHWKNCLRQDCPV 360
            RREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAHCASSRQIITHWKNCLRQDCPV
Sbjct: 301  RREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAHCASSRQIITHWKNCLRQDCPV 360

Query: 361  CFALKIADKRNTQGQSVNQTSTMTAPNAADPATMKRAFESLGLQYNQNTPAHNAAQHGHP 420
            CFALKIADKRNTQGQSVNQTSTMTAPNAADPATMKRAFESLGLQYNQNTPAHNAAQHGHP
Sbjct: 361  CFALKIADKRNTQGQSVNQTSTMTAPNAADPATMKRAFESLGLQYNQNTPAHNAAQHGHP 420

Query: 421  QMNAMQNDAGQINKTNMPNQQGPKVVPDQXXXXXXXXXXXXTGQLPQTIQPQSGTQLXXX 480
            QMNAMQNDAGQINKTNMPNQQGPKVVPDQ            TGQLPQTIQPQSGTQL   
Sbjct: 421  QMNAMQNDAGQINKTNMPNQQGPKVVPDQSSSPMSMLPVPPTGQLPQTIQPQSGTQLASA 480

Query: 481  XXXXXXXXXXPDIVKSIPVSSRKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMK 540
                      PDIVKSIPVSSRKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMK
Sbjct: 481  TAQAAAMGNAPDIVKSIPVSSRKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMK 540

Query: 541  NLVAYARKVEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQNAPNAQVPGMQ 600
            NLVAYARKVEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQNAPNAQVPGMQ
Sbjct: 541  NLVAYARKVEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQNAPNAQVPGMQ 600

Query: 601  GQIHPNAQNGPNNVQGNAFFXXXXXXXXXXXXXXXXXXXXLKMKWSNMRATPPPVQMPGV 660
            GQIHPNAQNGPNNVQGNAFF                    LKMKWSNMRATPPPVQMPGV
Sbjct: 601  GQIHPNAQNGPNNVQGNAFFNEMNNLPMPNQQQIQPPQGQLKMKWSNMRATPPPVQMPGV 660

Query: 661  ATSSTMTMNAALADSQQQFDAIKRSMPQQPGGMNRLMMPSATATSTXXXXXXXXXXXXXX 720
            ATSSTMTMNAALADSQQQFDAIKRSMPQQPGGMNRLMMPSATATST              
Sbjct: 661  ATSSTMTMNAALADSQQQFDAIKRSMPQQPGGMNRLMMPSATATSTHQSPQQPLLHQQLN 720

Query: 721  XXXXXXXXXXXXXXXMSTPQQSNLQNHMNSTLPDVLGGVNNQRMTGTPTVGGSLDSVVAT 780
                           MSTPQQSNLQNHMNSTLPDVLGGVNNQRMTGTPTVGGSLDSVVAT
Sbjct: 721  SQAQVVQSQASNQSAMSTPQQSNLQNHMNSTLPDVLGGVNNQRMTGTPTVGGSLDSVVAT 780

Query: 781  SGVHVATSQQSLIQLAGPAAATPVSQPHLPISRASQLNGQTPTQDLSNELSQVTDDLMKS 840
            SGVHVATSQQSLIQLAGPAAATPVSQPHLPISRASQLNGQTPTQDLSNELSQVTDDLMKS
Sbjct: 781  SGVHVATSQQSLIQLAGPAAATPVSQPHLPISRASQLNGQTPTQDLSNELSQVTDDLMKS 840

Query: 841  ESNNKDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPQKGDVKTES 900
            ESNNKD                                            PQKGDVKTES
Sbjct: 841  ESNNKDTALSESSQNLSSLLSAASPSTLSLTTMTPSVVTSSTTVSSMLNLPQKGDVKTES 900

Query: 901  STDXXXXXXXXXXXXXMDTGKSESEVKPEPDSIKAENETSSPKLDNLDESSQASIEEKPA 960
            STD             MDTGKSESEVKPEPDSIKAENETSSPKLDNLDESSQASIEEKPA
Sbjct: 901  STDVKVKQEVEVKEEKMDTGKSESEVKPEPDSIKAENETSSPKLDNLDESSQASIEEKPA 960

Query: 961  SVGDASNNSAASTPKPRCKKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIP 1020
            SVGDASNNSAASTPKPRCKKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIP
Sbjct: 961  SVGDASNNSAASTPKPRCKKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIP 1020

Query: 1021 DYFDIVKKPMDLSTIRRKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSE 1080
            DYFDIVKKPMDLSTIRRKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSE
Sbjct: 1021 DYFDIVKKPMDLSTIRRKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSE 1080

Query: 1081 VFESEIDSVMQSLGYCCGHKYVFCPQVLCCYGKQLCTIPRDSMYYSYQNRYVYCEKCFNE 1140
            VFESEIDSVMQSLGYCCGHKYVFCPQVLCCYGKQLCTIPRDSMYYSYQNRYVYCEKCFNE
Sbjct: 1081 VFESEIDSVMQSLGYCCGHKYVFCPQVLCCYGKQLCTIPRDSMYYSYQNRYVYCEKCFNE 1140

Query: 1141 IQTDEVELSEDPTQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWR 1200
            IQTDEVELSEDPTQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWR
Sbjct: 1141 IQTDEVELSEDPTQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWR 1200

Query: 1201 EGWSCDSCLKAKGVKRKENKFTSKKLPTTKLGTYLENRVNNFLRKKDSGAGEVTIRVLSS 1260
            EGWSCDSCLKAKGVKRKENKFTSKKLPTTKLGTYLENRVNNFLRKKDSGAGEVTIRVLSS
Sbjct: 1201 EGWSCDSCLKAKGVKRKENKFTSKKLPTTKLGTYLENRVNNFLRKKDSGAGEVTIRVLSS 1260

Query: 1261 YDKMTEVKPLMKKRFGNDMEDSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNT 1320
            YDKMTEVKPLMKKRFGNDMEDSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNT
Sbjct: 1261 YDKMTEVKPLMKKRFGNDMEDSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNT 1320

Query: 1321 RRVYISYLDSVHFFKPRHLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHC 1380
            RRVYISYLDSVHFFKPRHLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHC
Sbjct: 1321 RRVYISYLDSVHFFKPRHLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHC 1380

Query: 1381 HPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKDAIDSGISSAKDLAYFEGDFWP 1440
            HPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKDAIDSGISSAKDLAYFEGDFWP
Sbjct: 1381 HPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKDAIDSGISSAKDLAYFEGDFWP 1440

Query: 1441 NVIEESIKELDQXXXXXXXXXXXXXXXXXXXXQDTVEETTDAVCSDVAGTXXXXXXXXXX 1500
            NVIEESIKELDQ                    QDTVEETTDAVCSDVAGT          
Sbjct: 1441 NVIEESIKELDQEEEEKRRREEAEAAAAEAEAQDTVEETTDAVCSDVAGTKKGEKKGQRN 1500

Query: 1501 XXANKSKGSARKNNRKTNLPQGTNDLTAKLYNHMEKHKEVFFVIRLHNQQIAASLPPITE 1560
              ANKSKGSARKNNRKTNLPQGTNDLTAKLYNHMEKHKEVFFVIRLHNQQIAASLPPITE
Sbjct: 1501 KKANKSKGSARKNNRKTNLPQGTNDLTAKLYNHMEKHKEVFFVIRLHNQQIAASLPPITE 1560

Query: 1561 PDPAMSCELMDGRDAFLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCNSCK 1620
            PDPAMSCELMDGRDAFLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCNSCK
Sbjct: 1561 PDPAMSCELMDGRDAFLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCNSCK 1620

Query: 1621 AAVETRYHCSTCDDFDLCVPCYNKEGHHHKMTKLGLGLDDIASSDKEENPQESRRKSIQR 1680
            AAVETRYHCSTCDDFDLCVPCYNKEGHHHKMTKLGLGLDDIASSDKEENPQESRRKSIQR
Sbjct: 1621 AAVETRYHCSTCDDFDLCVPCYNKEGHHHKMTKLGLGLDDIASSDKEENPQESRRKSIQR 1680

Query: 1681 CISSLVHACQCRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCCYHAKHCV 1740
            CISSLVHACQCRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCCYHAKHCV
Sbjct: 1681 CISSLVHACQCRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCCYHAKHCV 1740

Query: 1741 ENKCQVPFCAXXXXXXXXXXXXTTLHQAQMLRRRVAIMXXXXXXXXXXXXXXXXXXXXXX 1800
            ENKCQVPFCA            TTLHQAQMLRRRVAIM                      
Sbjct: 1741 ENKCQVPFCAQLKQKLKQKQLLTTLHQAQMLRRRVAIMTGTTNTSTNNGPSSATPSSQDS 1800

Query: 1801 XXXXXXXXXXXXXGSVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPAINSIGKGAMQ 1860
                         GSV                                PAINSIGKGAMQ
Sbjct: 1801 PPQSTASQPSFTSGSVGKAPGAPPPRGALIAAQEAQVQAEAQRQGAGVPAINSIGKGAMQ 1860

Query: 1861 XXXXXXXXXXXXSTGKPMRXXXXXXXXXXXXXXXXXXXNMARDVRMQGMXXXXXXXXXXX 1920
                        STGKPMR                   NMARDVRMQGM           
Sbjct: 1861 PPIRPAAPAIVPSTGKPMRPQQAWPPSYPQAPSQQPRPNMARDVRMQGMQPHPQQQPQQQ 1920

Query: 1921 XXXXTMXXXXXXXXXXXXXXXXXXXXXXXXXVHTMLRAFKNQHLSQSEWLDLLRKNPQLM 1980
                TM                         VHTMLRAFKNQHLSQSEWLDLLRKNPQLM
Sbjct: 1921 QPVPTMGPSTGNATAGPAAAGGAGATPIGPAVHTMLRAFKNQHLSQSEWLDLLRKNPQLM 1980

Query: 1981 AQVLKLKNEKARM 1993
            AQVLKLKNEKARM
Sbjct: 1981 AQVLKLKNEKARM 1993

 Score =  233 bits (595), Expect = 2e-59
 Identities = 126/175 (72%), Positives = 126/175 (72%)

Query: 2071 FAQPQQPFVQRPRMNFPQQTFQNDTGXXXXXXXXXXXXXXXXXXXXXFMLAQQANPSSQQ 2130
            FAQPQQPFVQRPRMNFPQQTFQNDTG                     FMLAQQANPSSQQ
Sbjct: 2071 FAQPQQPFVQRPRMNFPQQTFQNDTGHNMHQFPQQHMMQHRQPMSPQFMLAQQANPSSQQ 2130

Query: 2131 MLNQVRSPPASAAGLXXXXXXXXXXXXXXXXXXXXXXXXXXXXHHNIVNNQSPLHGMGVG 2190
            MLNQVRSPPASAAGL                            HHNIVNNQSPLHGMGVG
Sbjct: 2131 MLNQVRSPPASAAGLPQTVRSPQPTPSPRQQPIPSPRQLQQSPHHNIVNNQSPLHGMGVG 2190

Query: 2191 QDTSQLSNDHVMLSSFQTHTTMTQLQNSDVSMGQQDNEVAPLTPQDKLANFVNQI 2245
            QDTSQLSNDHVMLSSFQTHTTMTQLQNSDVSMGQQDNEVAPLTPQDKLANFVNQI
Sbjct: 2191 QDTSQLSNDHVMLSSFQTHTTMTQLQNSDVSMGQQDNEVAPLTPQDKLANFVNQI 2245
>gi|7511830|pir||T13828 CREB-binding protein homolog - fruit fly (Drosophila melanogaster)
 gi|1916930|gb|AAB53050.1| CREB-binding protein homolog [Drosophila melanogaster]
          Length = 3190

 Score = 1062 bits (2746), Expect = 0.0
 Identities = 526/822 (63%), Positives = 625/822 (76%), Gaps = 24/822 (2%)

Query: 971  ASTPKPRCKKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPM 1030
            A   K +C+  F+ +ELR AL+PTLEKL++Q+PES+PFR PVDP  L IPDYF+IVKKPM
Sbjct: 1688 AGDKKKKCQ--FNPEELRTALLPTLEKLYRQEPESVPFRYPVDPQALGIPDYFEIVKKPM 1745

Query: 1031 DLSTIRRKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVM 1090
            DL TIR  + +G YSDPWEYVDDV LMFDNAWLYN KTSRVY+Y +KLSEVFE+EID VM
Sbjct: 1746 DLGTIRTNIQNGKYSDPWEYVDDVWLMFDNAWLYNPKTSRVYRYCTKLSEVFEAEIDPVM 1805

Query: 1091 QSLGYCCGHKYVFCPQVLCCYGKQLCTIPRDSMYYSYQ----------NRYVYCEKCFNE 1140
            Q+LGYCCG KY F PQVLCCYGKQLCTIPRD+ YYSYQ          NRY YC+KCFN+
Sbjct: 1806 QALGYCCGRKYTFNPQVLCCYGKQLCTIPRDAKYYSYQNSLKEYGVASNRYTYCQKCFND 1865

Query: 1141 IQTDEVELSEDPTQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWR 1200
            IQ D V L +DP Q  T+I+KDQF  +KND L+ EPF++CQECGR+ HQIC LW +SIW 
Sbjct: 1866 IQGDTVTLGDDPLQSQTQIKKDQFKEMKNDHLELEPFVNCQECGRKQHQICVLWLDSIWP 1925

Query: 1201 EGWSCDSCLKAKGVKRKENKFTSKKLPTTKLGTYLENRVNNFLRKKDSGAGEVTIRVLSS 1260
             G+ CD+CLK K  KRKENKF +K+LPTTKLG Y+E RVNNFL+KK++GAGEV IRV+SS
Sbjct: 1926 GGFVCDNCLKKKNSKRKENKFNAKRLPTTKLGVYIETRVNNFLKKKEAGAGEVHIRVVSS 1985

Query: 1261 YDKMTEVKPLMKKRF--GNDMEDSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGP 1318
             DK  EVKP M++RF    +M + +PYRAKA+FAFEE+DG+DVCFFGMHVQEYGS CP P
Sbjct: 1986 SDKCVEVKPGMRRRFVEQGEMMNEFPYRAKALFAFEEVDGIDVCFFGMHVQEYGSECPAP 2045

Query: 1319 NTRRVYISYLDSVHFFKPRHLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIF 1378
            NTRRVYI+YLDSVHFF+PR  RTAVYHEIL+GY++Y K LGYT AHIWACPPSEGDDYIF
Sbjct: 2046 NTRRVYIAYLDSVHFFRPRQYRTAVYHEILLGYMDYVKQLGYTMAHIWACPPSEGDDYIF 2105

Query: 1379 HCHPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKDAIDSGISSAKDLAYFEGDF 1438
            HCHP +QKIPKPKRLQEWYKKMLDK +I+R++ DYKDI K A++  + SA +L YFEGDF
Sbjct: 2106 HCHPTDQKIPKPKRLQEWYKKMLDKGMIERIIQDYKDILKQAMEDKLGSAAELPYFEGDF 2165

Query: 1439 WPNVIEESIKELDQXXXXXXXXXXXXXXXXXXXXQDTVEETTDAVCSDVAGTXXXXXXXX 1498
            WPNV+EESIKELDQ                      ++EE                    
Sbjct: 2166 WPNVLEESIKELDQEEEEKRKQAEAAEAAAAANLF-SIEENE-------VSGDGKKKGQK 2217

Query: 1499 XXXXANKSKGSARKNNRKTNLPQGTNDLTAKLYNHMEKHKEVFFVIRLHNQQIAASLPPI 1558
                +NKSK + RKN++K+N  Q  NDL+ K+Y  MEKHKEVFFVIRLH+ Q AASL PI
Sbjct: 2218 KAKKSNKSKAAQRKNSKKSNEHQSGNDLSTKIYATMEKHKEVFFVIRLHSAQSAASLAPI 2277

Query: 1559 TEPDPAMSCELMDGRDAFLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCNS 1618
             +PDP ++C+LMDGRDAFLT AR+KH+EFSSLRRA+ S++++LYELHNQG+D FVYTCN 
Sbjct: 2278 QDPDPLLTCDLMDGRDAFLTLARDKHFEFSSLRRAQFSTLSMLYELHNQGQDKFVYTCNH 2337

Query: 1619 CKAAVETRYHCSTCDDFDLCVPCYNKEGHHHKMTKLGLGLDDIA--SSDKEENPQESRRK 1676
            CK AVETRYHC+ CDDFDLC+ C  K GH HKM KLG  +DD +  +  K+ NPQE+R++
Sbjct: 2338 CKTAVETRYHCTVCDDFDLCIVCKEKVGHQHKMEKLGFDIDDGSALADHKQANPQEARKQ 2397

Query: 1677 SIQRCISSLVHACQCRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCCYHA 1736
            SIQRCI SL HACQCR+ANCR+ +C KMK VV HT +C+RK N GCPICKQLIALCCYHA
Sbjct: 2398 SIQRCIQSLAHACQCRDANCRLPSCQKMKLVVQHTKNCKRKPNGGCPICKQLIALCCYHA 2457

Query: 1737 KHCVENKCQVPFCAXXXXXXXXXXXXTTLHQAQMLRRRVAIM 1778
            K+C E KC VPFC                 Q Q+LRRRVA+M
Sbjct: 2458 KNCEEQKCPVPFCPNIKHKLKQQQSQQKFQQQQLLRRRVALM 2499

 Score =  128 bits (321), Expect = 1e-27
 Identities = 63/88 (71%), Positives = 71/88 (80%)

Query: 498  PVSSRKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARKVEGDMYESA 557
            P  + KDW   VT DLRNHLVHKLVQAIFPT D  T++D RM NLV+YA KVE DMYE A
Sbjct: 936  PGDNEKDWRESVTADLRNHLVHKLVQAIFPTSDPTTMQDKRMHNLVSYAEKVEKDMYEMA 995

Query: 558  NNRGQYYHLLAEKIYKIQKELEEKRIQR 585
             +R +YYHLLAEKIYKIQKELEEKR++R
Sbjct: 996  KSRSEYYHLLAEKIYKIQKELEEKRLKR 1023

 Score = 83.2 bits (204), Expect = 6e-14
 Identities = 45/86 (52%), Positives = 59/86 (68%), Gaps = 1/86 (1%)

Query: 281 DKSKLIQQQLVLLLHAHKCQRREQNNIEQE-CKLPYCRTMKNVLNHMTTCNKGKSCEVAH 339
           D+ + IQQQL+LLLHAHKC RRE  N  +E C + YC+ MK+VL HM TC + K C + H
Sbjct: 510 DRKRQIQQQLMLLLHAHKCNRRENLNPNREVCNVNYCKAMKSVLAHMGTCKQSKDCTMQH 569

Query: 340 CASSRQIITHWKNCLRQDCPVCFALK 365
           CASSRQI+ H+K C    C +C+  +
Sbjct: 570 CASSRQILLHYKTCQNSGCVICYPFR 595

 Score = 47.0 bits (110), Expect = 0.005
 Identities = 33/97 (34%), Positives = 47/97 (48%), Gaps = 14/97 (14%)

Query: 274  RQAAGEPDKSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGK 333
            +QA  +  + + IQ+ +  L  AH CQ R+ N     C+LP C+ MK V+ H   C +  
Sbjct: 2387 KQANPQEARKQSIQRCIQSL--AHACQCRDAN-----CRLPSCQKMKLVVQHTKNCKRKP 2439

Query: 334  SCEVAHCASSRQIIT----HWKNCLRQDCPVCFALKI 366
            +     C   +Q+I     H KNC  Q CPV F   I
Sbjct: 2440 N---GGCPICKQLIALCCYHAKNCEEQKCPVPFCPNI 2473
>gi|24640865|ref|NP_524642.2| nejire CG15319-PB [Drosophila melanogaster]
 gi|22833041|gb|AAF46516.2| CG15319-PB [Drosophila melanogaster]
          Length = 3276

 Score = 1057 bits (2734), Expect = 0.0
 Identities = 527/822 (64%), Positives = 626/822 (76%), Gaps = 24/822 (2%)

Query: 971  ASTPKPRCKKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPM 1030
            A   K +C+  F+ +ELR AL+PTLEKL++Q+PES+PFR PVDP  L IPDYF+IVKKPM
Sbjct: 1688 AGDKKKKCQ--FNPEELRTALLPTLEKLYRQEPESVPFRYPVDPQALGIPDYFEIVKKPM 1745

Query: 1031 DLSTIRRKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVM 1090
            DL TIR  + +G YSDPWEYVDDV LMFDNAWLYNRKTSRVY+Y +KLSEVFE+EID VM
Sbjct: 1746 DLGTIRTNIQNGKYSDPWEYVDDVWLMFDNAWLYNRKTSRVYRYCTKLSEVFEAEIDPVM 1805

Query: 1091 QSLGYCCGHKYVFCPQVLCCYGKQLCTIPRDSMYYSYQ----------NRYVYCEKCFNE 1140
            Q+LGYCCG KY F PQVLCCYGKQLCTIPRD+ YYSYQ          NRY YC+KCFN+
Sbjct: 1806 QALGYCCGRKYTFNPQVLCCYGKQLCTIPRDAKYYSYQNSLKEYGVASNRYTYCQKCFND 1865

Query: 1141 IQTDEVELSEDPTQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWR 1200
            IQ D V L +DP Q  T+I+KDQF  +KND L+ EPF++CQECGR+ HQIC LW +SIW 
Sbjct: 1866 IQGDTVTLGDDPLQSQTQIKKDQFKEMKNDHLELEPFVNCQECGRKQHQICVLWLDSIWP 1925

Query: 1201 EGWSCDSCLKAKGVKRKENKFTSKKLPTTKLGTYLENRVNNFLRKKDSGAGEVTIRVLSS 1260
             G+ CD+CLK K  KRKENKF +K+LPTTKLG Y+E RVNNFL+KK++GAGEV IRV+SS
Sbjct: 1926 GGFVCDNCLKKKNSKRKENKFNAKRLPTTKLGVYIETRVNNFLKKKEAGAGEVHIRVVSS 1985

Query: 1261 YDKMTEVKPLMKKRF--GNDMEDSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGP 1318
             DK  EVKP M++RF    +M + +PYRAKA+FAFEE+DG+DVCFFGMHVQEYGS CP P
Sbjct: 1986 SDKCVEVKPGMRRRFVEQGEMMNEFPYRAKALFAFEEVDGIDVCFFGMHVQEYGSECPAP 2045

Query: 1319 NTRRVYISYLDSVHFFKPRHLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIF 1378
            NTRRVYI+YLDSVHFF+PR  RTAVYHEIL+GY++Y K LGYT AHIWACPPSEGDDYIF
Sbjct: 2046 NTRRVYIAYLDSVHFFRPRQYRTAVYHEILLGYMDYVKQLGYTMAHIWACPPSEGDDYIF 2105

Query: 1379 HCHPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKDAIDSGISSAKDLAYFEGDF 1438
            HCHP +QKIPKPKRLQEWYKKMLDK +I+R++ DYKDI K A++  + SA +L YFEGDF
Sbjct: 2106 HCHPTDQKIPKPKRLQEWYKKMLDKGMIERIIQDYKDILKQAMEDKLGSAAELPYFEGDF 2165

Query: 1439 WPNVIEESIKELDQXXXXXXXXXXXXXXXXXXXXQDTVEETTDAVCSDVAGTXXXXXXXX 1498
            WPNV+EESIKELDQ                      ++EE                    
Sbjct: 2166 WPNVLEESIKELDQEEEEKRKQAEAAEAAAAANLF-SIEENE-------VSGDGKKKGQK 2217

Query: 1499 XXXXANKSKGSARKNNRKTNLPQGTNDLTAKLYNHMEKHKEVFFVIRLHNQQIAASLPPI 1558
                +NKSK + RKN++K+N  Q  NDL+ K+Y  MEKHKEVFFVIRLH+ Q AASL PI
Sbjct: 2218 KAKKSNKSKAAQRKNSKKSNEHQSGNDLSTKIYATMEKHKEVFFVIRLHSAQSAASLAPI 2277

Query: 1559 TEPDPAMSCELMDGRDAFLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCNS 1618
             +PDP ++C+LMDGRDAFLT AR+KH+EFSSLRRA+ S++++LYELHNQG+D FVYTCN 
Sbjct: 2278 QDPDPLLTCDLMDGRDAFLTLARDKHFEFSSLRRAQFSTLSMLYELHNQGQDKFVYTCNH 2337

Query: 1619 CKAAVETRYHCSTCDDFDLCVPCYNKEGHHHKMTKLGLGLDDIA--SSDKEENPQESRRK 1676
            CK AVETRYHC+ CDDFDLC+ C  K GH HKM KLG  +DD +  +  K+ NPQE+R++
Sbjct: 2338 CKTAVETRYHCTVCDDFDLCIVCKEKVGHQHKMEKLGFDIDDGSALADHKQANPQEARKQ 2397

Query: 1677 SIQRCISSLVHACQCRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCCYHA 1736
            SIQRCI SL HACQCR+ANCR+ +C KMK VV HT +C+RK N GCPICKQLIALCCYHA
Sbjct: 2398 SIQRCIQSLAHACQCRDANCRLPSCQKMKLVVQHTKNCKRKPNGGCPICKQLIALCCYHA 2457

Query: 1737 KHCVENKCQVPFCAXXXXXXXXXXXXTTLHQAQMLRRRVAIM 1778
            K+C E KC VPFC                 Q Q+LRRRVA+M
Sbjct: 2458 KNCEEQKCPVPFCPNIKHKLKQQQSQQKFQQQQLLRRRVALM 2499

 Score =  127 bits (319), Expect = 3e-27
 Identities = 63/88 (71%), Positives = 71/88 (80%)

Query: 498  PVSSRKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARKVEGDMYESA 557
            P  + KDW   VT DLRNHLVHKLVQAIFPT D  T++D RM NLV+YA KVE DMYE A
Sbjct: 936  PGDNEKDWRESVTADLRNHLVHKLVQAIFPTSDPTTMQDKRMHNLVSYAEKVEKDMYEMA 995

Query: 558  NNRGQYYHLLAEKIYKIQKELEEKRIQR 585
             +R +YYHLLAEKIYKIQKELEEKR++R
Sbjct: 996  KSRSEYYHLLAEKIYKIQKELEEKRLKR 1023

 Score = 82.4 bits (202), Expect = 8e-14
 Identities = 45/86 (52%), Positives = 59/86 (68%), Gaps = 1/86 (1%)

Query: 281 DKSKLIQQQLVLLLHAHKCQRREQNNIEQE-CKLPYCRTMKNVLNHMTTCNKGKSCEVAH 339
           D+ + IQQQL+LLLHAHKC RRE  N  +E C + YC+ MK+VL HM TC + K C + H
Sbjct: 510 DRKRQIQQQLMLLLHAHKCNRRENLNPNREVCNVNYCKAMKSVLAHMGTCKQSKDCTMQH 569

Query: 340 CASSRQIITHWKNCLRQDCPVCFALK 365
           CASSRQI+ H+K C    C +C+  +
Sbjct: 570 CASSRQILLHYKTCQNSGCVICYPFR 595

 Score = 46.2 bits (108), Expect = 0.006
 Identities = 33/97 (34%), Positives = 47/97 (48%), Gaps = 14/97 (14%)

Query: 274  RQAAGEPDKSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGK 333
            +QA  +  + + IQ+ +  L  AH CQ R+ N     C+LP C+ MK V+ H   C +  
Sbjct: 2387 KQANPQEARKQSIQRCIQSL--AHACQCRDAN-----CRLPSCQKMKLVVQHTKNCKRKP 2439

Query: 334  SCEVAHCASSRQIIT----HWKNCLRQDCPVCFALKI 366
            +     C   +Q+I     H KNC  Q CPV F   I
Sbjct: 2440 N---GGCPICKQLIALCCYHAKNCEEQKCPVPFCPNI 2473
>gi|4758056|ref|NP_004371.1| CREB binding protein [Homo sapiens]
 gi|3023440|sp|Q92793|CBP_HUMAN CREB-binding protein
 gi|2443859|gb|AAC51770.1| CREB-binding protein
          Length = 2442

 Score = 1038 bits (2684), Expect = 0.0
 Identities = 537/861 (62%), Positives = 637/861 (73%), Gaps = 24/861 (2%)

Query: 924  SEVKPEPDSIKAENETSSPKLDNLDESSQASIEEKPASVGDASNNSAASTPKPRCKKVFD 983
            S+VK E D  + ++E         +   +   EE+ +S G AS +++ S P+   KK+F 
Sbjct: 1030 SQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPR---KKIFK 1086

Query: 984  KDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPMDLSTIRRKLDSGL 1043
             +ELRQALMPTLE L++QDPESLPFRQPVDP +L IPDYFDIVK PMDLSTI+RKLD+G 
Sbjct: 1087 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQ 1146

Query: 1044 YSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVMQSLGYCCGHKYVF 1103
            Y +PW+YVDDV LMF+NAWLYNRKTSRVYK+ SKL+EVFE EID VMQSLGYCCG KY F
Sbjct: 1147 YQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEF 1206

Query: 1104 CPQVLCCYGKQLCTIPRDSMYYSYQNRYVYCEKCFNEIQTDEVELSEDPTQPMTKIRKDQ 1163
             PQ LCCYGKQLCTIPRD+ YYSYQNRY +CEKCF EIQ + V L +DP+QP T I KDQ
Sbjct: 1207 SPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQ 1266

Query: 1164 FDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREGWSCDSCLKAKGVKRKENKFTS 1223
            F++ KND LD EPF+DC+ECGR+ HQIC L ++ IW  G+ CD+CLK  G  RKENKF++
Sbjct: 1267 FEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSA 1326

Query: 1224 KKLPTTKLGTYLENRVNNFLRKKD-SGAGEVTIRVLSSYDKMTEVKPLMKKRF--GNDME 1280
            K+L TT+LG +LE+RVN FLR+++   AGEV +RV++S DK  EVKP MK RF    +M 
Sbjct: 1327 KRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMS 1386

Query: 1281 DSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISYLDSVHFFKPRHLR 1340
            +S+PYR KA+FAFEEIDGVDVCFFGMHVQEYGS CP PNTRRVYISYLDS+HFF+PR LR
Sbjct: 1387 ESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLR 1446

Query: 1341 TAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKM 1400
            TAVYHEILIGYLEY K LGY T HIWACPPSEGDDYIFHCHPP+QKIPKPKRLQEWYKKM
Sbjct: 1447 TAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM 1506

Query: 1401 LDKAIIDRVVVDYKDIFKDAIDSGISSAKDLAYFEGDFWPNVIEESIKELDQXXXXXXXX 1460
            LDKA  +R++ DYKDIFK A +  ++SAK+L YFEGDFWPNV+EESI             
Sbjct: 1507 LDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESI-----------KE 1555

Query: 1461 XXXXXXXXXXXXQDTVEETTDAVCSDVAGTXXXXXXXXXXXXANKSKGSARKNNRKTNLP 1520
                             ETT+    D                ++ S    R N +K ++P
Sbjct: 1556 LEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSIS----RANKKKPSMP 1611

Query: 1521 QGTNDLTAKLYNHMEKHKEVFFVIRLHNQQIAASLPPITEPDPAMSCELMDGRDAFLTTA 1580
              +NDL+ KLY  MEKHKEVFFVI LH   +  +LPPI +PDP +SC+LMDGRDAFLT A
Sbjct: 1612 NVSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLA 1671

Query: 1581 REKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCNSCKAAVETRYHCSTCDDFDLCVP 1640
            R+KH+EFSSLRR+K S++ +L ELH QG+D FVYTCN CK  VETR+HC+ C+D+DLC+ 
Sbjct: 1672 RDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCIN 1731

Query: 1641 CYNKEGHHHKMTKLGLGLDDIASSDKE---ENPQESRRKSIQRCISSLVHACQCRNANCR 1697
            CYN + H HKM K GLGLDD  SS  E   ++PQESRR SIQRCI SLVHACQCRNANC 
Sbjct: 1732 CYNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRVSIQRCIQSLVHACQCRNANCS 1791

Query: 1698 MNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCCYHAKHCVENKCQVPFCAXXXXXXX 1757
            + +C KMKRVV HT  C+RKTN GCP+CKQLIALCCYHAKHC ENKC VPFC        
Sbjct: 1792 LPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLR 1851

Query: 1758 XXXXXTTLHQAQMLRRRVAIM 1778
                   L QAQ++RRR+A M
Sbjct: 1852 QQQIQHRLQQAQLMRRRMATM 1872

 Score =  273 bits (699), Expect = 2e-71
 Identities = 186/372 (50%), Positives = 219/372 (58%), Gaps = 50/372 (13%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKGKSCEV 337
           +P+K KLIQQQLVLLLHAHKCQRREQ N E + C LP+CRTMKNVLNHMT C  GK+C+V
Sbjct: 347 DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQV 406

Query: 338 AHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRNTQ-----------------GQSVNQ 379
           AHCASSRQII+HWKNC R DCPVC  LK A DKRN Q                 G     
Sbjct: 407 AHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQN 466

Query: 380 TSTMTAPNAADPATMKRAFESLGLQYNQNTPAHNAAQHGHPQMNAMQNDAGQINKTNMPN 439
            ++++ PN  DP++M+RA+ +LGL Y  N P     Q   P     Q    Q  +T  P 
Sbjct: 467 ATSLSNPNPIDPSSMQRAYAALGLPY-MNQP-QTQLQPQVPGQQPAQPQTHQQMRTLNPL 524

Query: 440 QQGPKVVPDQXXXXXXXXXXXXTGQLPQTIQPQSG--TQLXXXXXXXXXXXXXPDI--VK 495
              P  +P              T Q P  +  +S   T L              +I  + 
Sbjct: 525 GNNPMNIP---------AGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLS 575

Query: 496 SIPVSS-------RKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARK 548
           +IP ++       RK WH  VTQDLR+HLVHKLVQAIFPTPD A L+D RM+NLVAYA+K
Sbjct: 576 TIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKK 635

Query: 549 VEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQ----NAPNAQVPGMQGQIH 604
           VEGDMYESAN+R +YYHLLAEKIYKIQKELEEKR  R+  Q    N P    PG Q  + 
Sbjct: 636 VEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVI 695

Query: 605 PNAQ-----NGP 611
           P AQ     NGP
Sbjct: 696 PQAQPVRPPNGP 707

 Score = 45.1 bits (105), Expect = 0.017
 Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 12/94 (12%)

Query: 280  PDKSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAH 339
            P +S+ +  Q  +    H CQ R  N     C LP C+ MK V+ H   C +  +     
Sbjct: 1764 PQESRRVSIQRCIQSLVHACQCRNAN-----CSLPSCQKMKRVVQHTKGCKRKTN---GG 1815

Query: 340  CASSRQIIT----HWKNCLRQDCPVCFALKIADK 369
            C   +Q+I     H K+C    CPV F L I  K
Sbjct: 1816 CPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHK 1849
>gi|4321116|gb|AAC51331.2| CREB-binding protein [Homo sapiens]
          Length = 2442

 Score = 1038 bits (2684), Expect = 0.0
 Identities = 537/861 (62%), Positives = 637/861 (73%), Gaps = 24/861 (2%)

Query: 924  SEVKPEPDSIKAENETSSPKLDNLDESSQASIEEKPASVGDASNNSAASTPKPRCKKVFD 983
            S+VK E D  + ++E         +   +   EE+ +S G AS +++ S P+   KK+F 
Sbjct: 1030 SQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPR---KKIFK 1086

Query: 984  KDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPMDLSTIRRKLDSGL 1043
             +ELRQALMPTLE L++QDPESLPFRQPVDP +L IPDYFDIVK PMDLSTI+RKLD+G 
Sbjct: 1087 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQ 1146

Query: 1044 YSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVMQSLGYCCGHKYVF 1103
            Y +PW+YVDDV LMF+NAWLYNRKTSRVYK+ SKL+EVFE EID VMQSLGYCCG KY F
Sbjct: 1147 YQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEF 1206

Query: 1104 CPQVLCCYGKQLCTIPRDSMYYSYQNRYVYCEKCFNEIQTDEVELSEDPTQPMTKIRKDQ 1163
             PQ LCCYGKQLCTIPRD+ YYSYQNRY +CEKCF EIQ + V L +DP+QP T I KDQ
Sbjct: 1207 SPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQ 1266

Query: 1164 FDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREGWSCDSCLKAKGVKRKENKFTS 1223
            F++ KND LD EPF+DC+ECGR+ HQIC L ++ IW  G+ CD+CLK  G  RKENKF++
Sbjct: 1267 FEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSA 1326

Query: 1224 KKLPTTKLGTYLENRVNNFLRKKD-SGAGEVTIRVLSSYDKMTEVKPLMKKRF--GNDME 1280
            K+L TT+LG +LE+RVN FLR+++   AGEV +RV++S DK  EVKP MK RF    +M 
Sbjct: 1327 KRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMS 1386

Query: 1281 DSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISYLDSVHFFKPRHLR 1340
            +S+PYR KA+FAFEEIDGVDVCFFGMHVQEYGS CP PNTRRVYISYLDS+HFF+PR LR
Sbjct: 1387 ESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLR 1446

Query: 1341 TAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKM 1400
            TAVYHEILIGYLEY K LGY T HIWACPPSEGDDYIFHCHPP+QKIPKPKRLQEWYKKM
Sbjct: 1447 TAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM 1506

Query: 1401 LDKAIIDRVVVDYKDIFKDAIDSGISSAKDLAYFEGDFWPNVIEESIKELDQXXXXXXXX 1460
            LDKA  +R++ DYKDIFK A +  ++SAK+L YFEGDFWPNV+EESI             
Sbjct: 1507 LDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESI-----------KE 1555

Query: 1461 XXXXXXXXXXXXQDTVEETTDAVCSDVAGTXXXXXXXXXXXXANKSKGSARKNNRKTNLP 1520
                             ETT+    D                ++ S    R N +K ++P
Sbjct: 1556 LEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSIS----RANKKKPSMP 1611

Query: 1521 QGTNDLTAKLYNHMEKHKEVFFVIRLHNQQIAASLPPITEPDPAMSCELMDGRDAFLTTA 1580
              +NDL+ KLY  MEKHKEVFFVI LH   +  +LPPI +PDP +SC+LMDGRDAFLT A
Sbjct: 1612 NVSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLA 1671

Query: 1581 REKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCNSCKAAVETRYHCSTCDDFDLCVP 1640
            R+KH+EFSSLRR+K S++ +L ELH QG+D FVYTCN CK  VETR+HC+ C+D+DLC+ 
Sbjct: 1672 RDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCIN 1731

Query: 1641 CYNKEGHHHKMTKLGLGLDDIASSDKE---ENPQESRRKSIQRCISSLVHACQCRNANCR 1697
            CYN + H HKM K GLGLDD  SS  E   ++PQESRR SIQRCI SLVHACQCRNANC 
Sbjct: 1732 CYNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCS 1791

Query: 1698 MNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCCYHAKHCVENKCQVPFCAXXXXXXX 1757
            + +C KMKRVV HT  C+RKTN GCP+CKQLIALCCYHAKHC ENKC VPFC        
Sbjct: 1792 LPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLR 1851

Query: 1758 XXXXXTTLHQAQMLRRRVAIM 1778
                   L QAQ++RRR+A M
Sbjct: 1852 QQQIQHRLQQAQLMRRRMATM 1872

 Score =  273 bits (699), Expect = 2e-71
 Identities = 186/372 (50%), Positives = 219/372 (58%), Gaps = 50/372 (13%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKGKSCEV 337
           +P+K KLIQQQLVLLLHAHKCQRREQ N E + C LP+CRTMKNVLNHMT C  GK+C+V
Sbjct: 347 DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQV 406

Query: 338 AHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRNTQ-----------------GQSVNQ 379
           AHCASSRQII+HWKNC R DCPVC  LK A DKRN Q                 G     
Sbjct: 407 AHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQN 466

Query: 380 TSTMTAPNAADPATMKRAFESLGLQYNQNTPAHNAAQHGHPQMNAMQNDAGQINKTNMPN 439
            ++++ PN  DP++M+RA+ +LGL Y  N P     Q   P     Q    Q  +T  P 
Sbjct: 467 ATSLSNPNPIDPSSMQRAYAALGLPY-MNQP-QTQLQPQVPGQQPAQPQTHQQMRTLNPL 524

Query: 440 QQGPKVVPDQXXXXXXXXXXXXTGQLPQTIQPQSG--TQLXXXXXXXXXXXXXPDI--VK 495
              P  +P              T Q P  +  +S   T L              +I  + 
Sbjct: 525 GNNPMNIP---------AGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLS 575

Query: 496 SIPVSS-------RKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARK 548
           +IP ++       RK WH  VTQDLR+HLVHKLVQAIFPTPD A L+D RM+NLVAYA+K
Sbjct: 576 TIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKK 635

Query: 549 VEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQ----NAPNAQVPGMQGQIH 604
           VEGDMYESAN+R +YYHLLAEKIYKIQKELEEKR  R+  Q    N P    PG Q  + 
Sbjct: 636 VEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVI 695

Query: 605 PNAQ-----NGP 611
           P AQ     NGP
Sbjct: 696 PQAQPVRPPNGP 707

 Score = 44.7 bits (104), Expect = 0.023
 Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 12/94 (12%)

Query: 280  PDKSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAH 339
            P +S+ +  Q  +    H CQ R  N     C LP C+ MK V+ H   C +  +     
Sbjct: 1764 PQESRRLSIQRCIQSLVHACQCRNAN-----CSLPSCQKMKRVVQHTKGCKRKTN---GG 1815

Query: 340  CASSRQIIT----HWKNCLRQDCPVCFALKIADK 369
            C   +Q+I     H K+C    CPV F L I  K
Sbjct: 1816 CPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHK 1849
>gi|19547885|gb|AAL87531.1| CREB-binding protein [Mus musculus]
 gi|19547887|gb|AAL87532.1| CREB-binding protein [Mus musculus]
          Length = 2429

 Score = 1032 bits (2668), Expect = 0.0
 Identities = 533/866 (61%), Positives = 636/866 (73%), Gaps = 28/866 (3%)

Query: 921  KSESEVKPEPDSIKAENETSSPKLDNLDESSQASIEEKPASVGDASNNSAASTPKPRC-- 978
            +  S+VK E D+ + ++E        ++E       E      ++SN++A+ +  P    
Sbjct: 1022 QGSSQVKEETDTTEQKSEPME-----VEEKKPEVKVEAKEEEENSSNDTASQSTSPSQPR 1076

Query: 979  KKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPMDLSTIRRK 1038
            KK+F  +ELRQALMPTLE L++QDPESLPFRQPVDP +L IPDYFDIVK PMDLSTI+RK
Sbjct: 1077 KKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRK 1136

Query: 1039 LDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVMQSLGYCCG 1098
            LD+G Y +PW+YVDDV LMF+NAWLYNRKTSRVYK+ SKL+EVFE EID VMQSLGYCCG
Sbjct: 1137 LDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCG 1196

Query: 1099 HKYVFCPQVLCCYGKQLCTIPRDSMYYSYQNRYVYCEKCFNEIQTDEVELSEDPTQPMTK 1158
             KY F PQ LCCYGKQLCTIPRD+ YYSYQNRY +CEKCF EIQ + V L +DP+QP T 
Sbjct: 1197 RKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTT 1256

Query: 1159 IRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREGWSCDSCLKAKGVKRKE 1218
            I KDQF++ KND LD EPF+DC+ECGR+ HQIC L ++ IW  G+ CD+CLK  G  RKE
Sbjct: 1257 ISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKE 1316

Query: 1219 NKFTSKKLPTTKLGTYLENRVNNFLRKKD-SGAGEVTIRVLSSYDKMTEVKPLMKKRF-- 1275
            NKF++K+L TT+LG +LE+RVN FLR+++   AGEV +RV++S DK  EVKP MK RF  
Sbjct: 1317 NKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVD 1376

Query: 1276 GNDMEDSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISYLDSVHFFK 1335
              +M +S+PYR KA+FAFEEIDGVDVCFFGMHVQEYGS CP PNTRRVYISYLDS+HFF+
Sbjct: 1377 SGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFR 1436

Query: 1336 PRHLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQE 1395
            PR LRTAVYHEILIGYLEY K LGY T HIWACPPSEGDDYIFHCHPP+QKIPKPKRLQE
Sbjct: 1437 PRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQE 1496

Query: 1396 WYKKMLDKAIIDRVVVDYKDIFKDAIDSGISSAKDLAYFEGDFWPNVIEESIKELDQXXX 1455
            WYKKMLDKA  +R++ DYKDIFK A +  ++SAK+L YFEGDFWPNV+EESI        
Sbjct: 1497 WYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESI-------- 1548

Query: 1456 XXXXXXXXXXXXXXXXXQDTVEETTDAVCSDVAGTXXXXXXXXXXXXANKSKGSARKNNR 1515
                                  ET +    D                ++ S    R N +
Sbjct: 1549 ---KELEQEEEERKKEESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSIS----RANKK 1601

Query: 1516 KTNLPQGTNDLTAKLYNHMEKHKEVFFVIRLHNQQIAASLPPITEPDPAMSCELMDGRDA 1575
            K ++P  +NDL+ KLY  MEKHKEVFFVI LH   + ++ PPI +PDP +SC+LMDGRDA
Sbjct: 1602 KPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDA 1661

Query: 1576 FLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCNSCKAAVETRYHCSTCDDF 1635
            FLT AR+KH+EFSSLRR+K S++ +L ELH QG+D FVYTCN CK  VETR+HC+ C+D+
Sbjct: 1662 FLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDY 1721

Query: 1636 DLCVPCYNKEGHHHKMTKLGLGLDDIASSDKE---ENPQESRRKSIQRCISSLVHACQCR 1692
            DLC+ CYN + H HKM K GLGLDD  SS  E   ++PQESRR SIQRCI SLVHACQCR
Sbjct: 1722 DLCINCYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCR 1781

Query: 1693 NANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCCYHAKHCVENKCQVPFCAXX 1752
            NANC + +C KMKRVV HT  C+RKTN GCP+CKQLIALCCYHAKHC ENKC VPFC   
Sbjct: 1782 NANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNI 1841

Query: 1753 XXXXXXXXXXTTLHQAQMLRRRVAIM 1778
                        L QAQ++RRR+A M
Sbjct: 1842 KHKLRQQQIQHRLQQAQLMRRRMATM 1867

 Score =  268 bits (686), Expect = 7e-70
 Identities = 185/377 (49%), Positives = 221/377 (58%), Gaps = 60/377 (15%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKGKSCEV 337
           +P+K KLIQQQLVLLLHAHKCQRREQ N E + C LP+CRTMKNVLNHMT C  GK+C+V
Sbjct: 340 DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQV 399

Query: 338 AHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRNTQ-----------------GQSVNQ 379
           AHCASSRQII+HWKNC R DCPVC  LK A DKRN Q                 G     
Sbjct: 400 AHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQN 459

Query: 380 TSTMTAPNAADPATMKRAFESLGLQY-NQ-----------NTPAHNAAQHGHPQMNAMQN 427
            ++++ PN  DP++M+RA+ +LGL Y NQ             PA   A      +NA+ N
Sbjct: 460 ATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPPAHQQMRTLNALGN 519

Query: 428 DAGQINKTNM-PNQQGPKVVPDQXXXXXXXXXXXXTGQLPQTIQPQSGTQLXXXXXXXXX 486
           +   I    +  +QQ P ++ +                LP ++   +   L         
Sbjct: 520 NPMSIPAGGITTDQQPPNLISES--------------ALPTSL--GATNPLMNDGSNSGN 563

Query: 487 XXXXPDIVKSIPVSS---RKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLV 543
                 I  + P SS   RK WH  VTQDLR+HLVHKLVQAIFPTPD A L+D RM+NLV
Sbjct: 564 IGSLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLV 623

Query: 544 AYARKVEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQ----NAPNAQVPGM 599
           AYA+KVEGDMYESAN+R +YYHLLAEKIYKIQKELEEKR  R+  Q    N P     G 
Sbjct: 624 AYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPASGA 683

Query: 600 QGQIHPNAQ-----NGP 611
           Q  + P AQ     NGP
Sbjct: 684 QPPVIPPAQSVRPPNGP 700

 Score = 44.3 bits (103), Expect = 0.026
 Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 12/94 (12%)

Query: 280  PDKSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAH 339
            P +S+ +  Q  +    H CQ R  N     C LP C+ MK V+ H   C +  +     
Sbjct: 1759 PQESRRLSIQRCIQSLVHACQCRNAN-----CSLPSCQKMKRVVQHTKGCKRKTN---GG 1810

Query: 340  CASSRQIIT----HWKNCLRQDCPVCFALKIADK 369
            C   +Q+I     H K+C    CPV F L I  K
Sbjct: 1811 CPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHK 1844
>gi|4557557|ref|NP_001420.1| E1A binding protein p300; E1A-binding protein, 300kD [Homo sapiens]
 gi|3024341|sp|Q09472|P300_HUMAN E1A-associated protein p300
 gi|627657|pir||A54277 transcription adaptor protein p300 - human
 gi|495301|gb|AAA18639.1| p300 protein
          Length = 2414

 Score = 1022 bits (2643), Expect = 0.0
 Identities = 537/868 (61%), Positives = 635/868 (73%), Gaps = 34/868 (3%)

Query: 927  KPEPDSIKAENETSSPKLDNLDESSQASIEEKPASV--------GDASNNSAASTPKP-- 976
            +PEP   + E+ + S   D   ES++   EE+   +           S ++  S+P P  
Sbjct: 986  QPEPADTQPEDISESKVEDCKMESTET--EERSTELKTEIKEEEDQPSTSATQSSPAPGQ 1043

Query: 977  RCKKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPMDLSTIR 1036
              KK+F  +ELRQALMPTLE L++QDPESLPFRQPVDP +L IPDYFDIVK PMDLSTI+
Sbjct: 1044 SKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIK 1103

Query: 1037 RKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVMQSLGYC 1096
            RKLD+G Y +PW+YVDD+ LMF+NAWLYNRKTSRVYKY SKLSEVFE EID VMQSLGYC
Sbjct: 1104 RKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYC 1163

Query: 1097 CGHKYVFCPQVLCCYGKQLCTIPRDSMYYSYQNRYVYCEKCFNEIQTDEVELSEDPTQPM 1156
            CG K  F PQ LCCYGKQLCTIPRD+ YYSYQNRY +CEKCFNEIQ + V L +DP+QP 
Sbjct: 1164 CGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQ 1223

Query: 1157 TKIRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREGWSCDSCLKAKGVKR 1216
            T I K+QF + KND LD E F++C ECGR+ HQIC L  E IW  G+ CD CLK     R
Sbjct: 1224 TTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTR 1283

Query: 1217 KENKFTSKKLPTTKLGTYLENRVNNFLRKKD-SGAGEVTIRVLSSYDKMTEVKPLMKKRF 1275
            KENKF++K+LP+T+LGT+LENRVN+FLR+++   +GEVT+RV+ + DK  EVKP MK RF
Sbjct: 1284 KENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARF 1343

Query: 1276 --GNDMEDSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISYLDSVHF 1333
                +M +S+PYR KA+FAFEEIDGVD+CFFGMHVQEYGS CP PN RRVYISYLDSVHF
Sbjct: 1344 VDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHF 1403

Query: 1334 FKPRHLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRL 1393
            F+P+ LRTAVYHEILIGYLEY K LGYTT HIWACPPSEGDDYIFHCHPP+QKIPKPKRL
Sbjct: 1404 FRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRL 1463

Query: 1394 QEWYKKMLDKAIIDRVVVDYKDIFKDAIDSGISSAKDLAYFEGDFWPNVIEESIKELDQX 1453
            QEWYKKMLDKA+ +R+V DYKDIFK A +  ++SAK+L YFEGDFWPNV+EESI      
Sbjct: 1464 QEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESI------ 1517

Query: 1454 XXXXXXXXXXXXXXXXXXXQDTVEETTDAVCSDVAGTXXXXXXXXXXXXANKSKGSARKN 1513
                               ++T  E+TD    D                ++ S+G    N
Sbjct: 1518 ------KELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRG----N 1567

Query: 1514 NRKTNLPQGTNDLTAKLYNHMEKHKEVFFVIRLHNQQIAASLPPITEPDPAMSCELMDGR 1573
             +K  +P  +NDL+ KLY  MEKHKEVFFVIRL     A SLPPI +PDP + C+LMDGR
Sbjct: 1568 KKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLIPCDLMDGR 1627

Query: 1574 DAFLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCNSCKAAVETRYHCSTCD 1633
            DAFLT AR+KH EFSSLRRA+ S+M +L ELH Q +D FVYTCN CK  VETR+HC+ C+
Sbjct: 1628 DAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCE 1687

Query: 1634 DFDLCVPCYNKEGHHHKMTKLGLGLDDIASSDK---EENPQESRRKSIQRCISSLVHACQ 1690
            D+DLC+ CYN + H HKM KLGLGLDD +++ +    ++P +SRR SIQRCI SLVHACQ
Sbjct: 1688 DYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQ 1747

Query: 1691 CRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCCYHAKHCVENKCQVPFCA 1750
            CRNANC + +C KMKRVV HT  C+RKTN GCPICKQLIALCCYHAKHC ENKC VPFC 
Sbjct: 1748 CRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCL 1807

Query: 1751 XXXXXXXXXXXXTTLHQAQMLRRRVAIM 1778
                          L QAQMLRRR+A M
Sbjct: 1808 NIKQKLRQQQLQHRLQQAQMLRRRMASM 1835

 Score =  266 bits (680), Expect = 3e-69
 Identities = 175/352 (49%), Positives = 204/352 (57%), Gaps = 26/352 (7%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKGKSCEV 337
           +P+K KLIQQQLVLLLHAHKCQRREQ N E ++C LP+CRTMKNVLNHMT C  GKSC+V
Sbjct: 331 DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQV 390

Query: 338 AHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRNTQ-----------GQSVNQTSTMTA 385
           AHCASSRQII+HWKNC R DCPVC  LK A DKRN Q             S       +A
Sbjct: 391 AHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNPSSLGVGQQSA 450

Query: 386 PNAA-----DPATMKRAFESLGLQYNQNTPAHNAAQHGHPQMNAMQNDAGQINKTNMPNQ 440
           PN +     DP++++RA+ +LGL Y  N            Q N     + Q  +      
Sbjct: 451 PNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGMRPMSNMS 510

Query: 441 QGPKVVPDQXXXXXXXXXXXXTGQLPQTIQPQSGTQLXXXXXXXXXXXXXPDIVKSIPVS 500
             P  V                  L   I  Q+   +             P   +     
Sbjct: 511 ASPMGV--NGGVGVQTPSLLSDSMLHSAINSQN--PMMSENASVPSLGPMPTAAQPSTTG 566

Query: 501 SRKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARKVEGDMYESANNR 560
            RK WH  +TQDLRNHLVHKLVQAIFPTPD A L+D RM+NLVAYARKVEGDMYESANNR
Sbjct: 567 IRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNR 626

Query: 561 GQYYHLLAEKIYKIQKELEEKRIQRMKVQNAPNAQVPGMQGQIHPNAQNGPN 612
            +YYHLLAEKIYKIQKELEEKR  R++ QN     +P   G +  +   GPN
Sbjct: 627 AEYYHLLAEKIYKIQKELEEKRRTRLQKQN----MLPNAAGMVPVSMNPGPN 674

 Score = 43.1 bits (100), Expect = 0.069
 Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 12/95 (12%)

Query: 276  AAGEPDKSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSC 335
            A   P  S+ +  Q  +    H CQ R  N     C LP C+ MK V+ H   C +  + 
Sbjct: 1723 ATQSPGDSRRLSIQRCIQSLVHACQCRNAN-----CSLPSCQKMKRVVQHTKGCKRKTN- 1776

Query: 336  EVAHCASSRQIIT----HWKNCLRQDCPVCFALKI 366
                C   +Q+I     H K+C    CPV F L I
Sbjct: 1777 --GGCPICKQLIALCCYHAKHCQENKCPVPFCLNI 1809
>gi|631119|pir||S39162 transcription coactivator CREB-binding protein - human
          Length = 2440

 Score = 1004 bits (2595), Expect = 0.0
 Identities = 525/861 (60%), Positives = 628/861 (72%), Gaps = 24/861 (2%)

Query: 924  SEVKPEPDSIKAENETSSPKLDNLDESSQASIEEKPASVGDASNNSAASTPKPRCKKVFD 983
            S+VK E D  + ++E    +    +   +   EE+ +S G AS +++ S P+   KK+F 
Sbjct: 1030 SQVKEETDIAEQKSEPMEVEDKKPEVKVEVKEEEESSSNGTASQSTSPSQPR---KKIFK 1086

Query: 984  KDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPMDLSTIRRKLDSGL 1043
             +ELRQALMPTLE L++QDPESLPFRQPVDP +L IPDYFDIVK PMDLSTI+RKLD+G 
Sbjct: 1087 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQ 1146

Query: 1044 YSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVMQSLGYCCGHKYVF 1103
            Y +PW+YVDDV LMF+NAWLYNRKTSRVYK+ SKL+EVFE EID VMQSLGYCCG KY F
Sbjct: 1147 YQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEF 1206

Query: 1104 CPQVLCCYGKQLCTIPRDSMYYSYQNRYVYCEKCFNEIQTDEVELSEDPTQPMTKIRKDQ 1163
             PQ LCCYGKQLCTIPRD+ YYSYQNRY +CEKCF EIQ + V L +DP+QP T I KDQ
Sbjct: 1207 SPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQ 1266

Query: 1164 FDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREGWSCDSCLKAKGVKRKENKFTS 1223
            F++ KND LD EPF+DC+ECGR+ HQIC L ++ IW  G+ CD+CLK  G  RKENKF++
Sbjct: 1267 FEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSA 1326

Query: 1224 KKLPTTKLGTYLENRVNNFLRKKD-SGAGEVTIRVLSSYDKMTEVKPLMKKRF--GNDME 1280
            K+L TT+LG +LE+RVN FLR+++   AGEV +RV++S DK  EVKP MK RF    +M 
Sbjct: 1327 KRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMS 1386

Query: 1281 DSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISYLDSVHFFKPRHLR 1340
            +S+PYR KA+FAFEEIDGVDVCFFGMHVQ+     P      VYISYLDS+HFF+PR LR
Sbjct: 1387 ESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSIHFFRPRCLR 1446

Query: 1341 TAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKM 1400
            TAVYHEILIGYLEY K L Y TAHIWACPPSEGDDYIFHCHPP+QKIPKPKRLQEWYKKM
Sbjct: 1447 TAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKM 1506

Query: 1401 LDKAIIDRVVVDYKDIFKDAIDSGISSAKDLAYFEGDFWPNVIEESIKELDQXXXXXXXX 1460
            LDKA  +R++ DYKDIFK A +  ++SAK+L YFEGDFWPNV+EESI             
Sbjct: 1507 LDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESI-----------KE 1555

Query: 1461 XXXXXXXXXXXXQDTVEETTDAVCSDVAGTXXXXXXXXXXXXANKSKGSARKNNRKTNLP 1520
                             ET +    D                ++ S    R N +K ++P
Sbjct: 1556 LEQEEEERKKEESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSIS----RANKKKPSMP 1611

Query: 1521 QGTNDLTAKLYNHMEKHKEVFFVIRLHNQQIAASLPPITEPDPAMSCELMDGRDAFLTTA 1580
              +NDL+ KLY  MEKHKEVFFVI LH   + ++ PPI +PDP +SC+LMDGRDAFLT A
Sbjct: 1612 NVSNDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLA 1671

Query: 1581 REKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCNSCKAAVETRYHCSTCDDFDLCVP 1640
            R+KH+EFSSLRR+K S++ +L ELH QG+D FVYTCN CK  VETR+HC+ C+D+DLC+ 
Sbjct: 1672 RDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCIN 1731

Query: 1641 CYNKEGHHHKMTKLGLGLDDIASSDKE---ENPQESRRKSIQRCISSLVHACQCRNANCR 1697
            CYN + H HKM K GLGLDD  SS  E   ++PQESRR SIQRCI SLVHACQCRNANC 
Sbjct: 1732 CYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCS 1791

Query: 1698 MNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCCYHAKHCVENKCQVPFCAXXXXXXX 1757
            + +C KMKRVV HT  C+RKTN GCP+CKQLIALCCYHAKHC ENKC VPFC        
Sbjct: 1792 LPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHNVR 1851

Query: 1758 XXXXXTTLHQAQMLRRRVAIM 1778
                   L QAQ++RRR+A M
Sbjct: 1852 QQQIQHCLQQAQLMRRRMATM 1872

 Score =  273 bits (699), Expect = 2e-71
 Identities = 186/372 (50%), Positives = 219/372 (58%), Gaps = 50/372 (13%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKGKSCEV 337
           +P+K KLIQQQLVLLLHAHKCQRREQ N E + C LP+CRTMKNVLNHMT C  GK+C+V
Sbjct: 347 DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQV 406

Query: 338 AHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRNTQ-----------------GQSVNQ 379
           AHCASSRQII+HWKNC R DCPVC  LK A DKRN Q                 G     
Sbjct: 407 AHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQN 466

Query: 380 TSTMTAPNAADPATMKRAFESLGLQYNQNTPAHNAAQHGHPQMNAMQNDAGQINKTNMPN 439
            ++++ PN  DP++M+RA+ +LGL Y  N P     Q   P     Q    Q  +T  P 
Sbjct: 467 ATSLSNPNPIDPSSMQRAYAALGLPY-MNQP-QTQLQPQVPGQQPAQPQTHQQMRTLNPL 524

Query: 440 QQGPKVVPDQXXXXXXXXXXXXTGQLPQTIQPQSG--TQLXXXXXXXXXXXXXPDI--VK 495
              P  +P              T Q P  +  +S   T L              +I  + 
Sbjct: 525 GNNPMNIP---------AGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLS 575

Query: 496 SIPVSS-------RKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARK 548
           +IP ++       RK WH  VTQDLR+HLVHKLVQAIFPTPD A L+D RM+NLVAYA+K
Sbjct: 576 TIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKK 635

Query: 549 VEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQ----NAPNAQVPGMQGQIH 604
           VEGDMYESAN+R +YYHLLAEKIYKIQKELEEKR  R+  Q    N P    PG Q  + 
Sbjct: 636 VEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVI 695

Query: 605 PNAQ-----NGP 611
           P AQ     NGP
Sbjct: 696 PQAQSVRPPNGP 707

 Score = 43.5 bits (101), Expect = 0.045
 Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 12/91 (13%)

Query: 280  PDKSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAH 339
            P +S+ +  Q  +    H CQ R  N     C LP C+ MK V+ H   C +  +     
Sbjct: 1764 PQESRRLSIQRCIQSLVHACQCRNAN-----CSLPSCQKMKRVVQHTKGCKRKTN---GG 1815

Query: 340  CASSRQIIT----HWKNCLRQDCPVCFALKI 366
            C   +Q+I     H K+C    CPV F L I
Sbjct: 1816 CPVCKQLIALCCYHAKHCQENKCPVPFCLNI 1846
>gi|737920|prf||1923401A protein CBP
          Length = 2441

 Score = 1000 bits (2585), Expect = 0.0
 Identities = 522/866 (60%), Positives = 626/866 (72%), Gaps = 28/866 (3%)

Query: 921  KSESEVKPEPDSIKAENETSSPKLDNLDESSQASIEEKPASVGDASNNSAASTPKPRC-- 978
            +  S+VK E D+ + ++E        ++E       E      ++SN++A+ +  P    
Sbjct: 1028 QGSSQVKEETDTTEQKSEPME-----VEEKKPEVKVEAKEEEENSSNDTASQSTSPSQPR 1082

Query: 979  KKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPMDLSTIRRK 1038
            KK+F  +ELRQALMPTLE L++QDPESLPFRQPVDP +L IPDYFDIVK PMDLSTI+RK
Sbjct: 1083 KKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRK 1142

Query: 1039 LDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVMQSLGYCCG 1098
            LD+G Y +PW+YVDDV LMF+NAWLYNRKTSRVYK+ SKL+EVFE EID VMQSLGYCCG
Sbjct: 1143 LDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCG 1202

Query: 1099 HKYVFCPQVLCCYGKQLCTIPRDSMYYSYQNRYVYCEKCFNEIQTDEVELSEDPTQPMTK 1158
             KY F PQ LCCYGKQLCTIPRD+ YYSYQNRY +C KCF EIQ + V L +DP+QP T 
Sbjct: 1203 RKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCGKCFTEIQGENVTLGDDPSQPQTT 1262

Query: 1159 IRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREGWSCDSCLKAKGVKRKE 1218
            I KDQF++ KND LD EPF+DC+ECGR+ HQIC L ++ IW  G+ CD+CLK  G  RKE
Sbjct: 1263 ISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKE 1322

Query: 1219 NKFTSKKLPTTKLGTYLENRVNNFLRKKD-SGAGEVTIRVLSSYDKMTEVKPLMKKRF-- 1275
            NKF++K+L TT+LG +LE+RVN FLR+++   AGEV +RV++S DK  EVKP MK RF  
Sbjct: 1323 NKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVD 1382

Query: 1276 GNDMEDSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISYLDSVHFFK 1335
              +M +S+PYR KA+FAFEEIDGVDVCFFGMHVQ+     P      VYISYLDS+HFF+
Sbjct: 1383 SGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSIHFFR 1442

Query: 1336 PRHLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQE 1395
            PR LRTAVYHEILIGYLEY K L Y TAHIWACPPSEGDDYIFHCHPP+QKIPKPKRLQE
Sbjct: 1443 PRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQE 1502

Query: 1396 WYKKMLDKAIIDRVVVDYKDIFKDAIDSGISSAKDLAYFEGDFWPNVIEESIKELDQXXX 1455
            WYKKMLDKA  +R++ DYKDIFK A +  ++SAK+L YFEGDFWPNV+EESI        
Sbjct: 1503 WYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESI-------- 1554

Query: 1456 XXXXXXXXXXXXXXXXXQDTVEETTDAVCSDVAGTXXXXXXXXXXXXANKSKGSARKNNR 1515
                                  ET +    D                ++ S    R N +
Sbjct: 1555 ---KELEQEEEERKKEESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSIS----RANKK 1607

Query: 1516 KTNLPQGTNDLTAKLYNHMEKHKEVFFVIRLHNQQIAASLPPITEPDPAMSCELMDGRDA 1575
            K ++P  +NDL+ KLY  MEKHKEVFFVI LH   + ++ PPI +PDP +SC+LMDGRDA
Sbjct: 1608 KPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDA 1667

Query: 1576 FLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCNSCKAAVETRYHCSTCDDF 1635
            FLT AR+KH+EFSSLRR+K S++ +L ELH QG+D FVYTCN CK  VETR+HC+ C+D+
Sbjct: 1668 FLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDY 1727

Query: 1636 DLCVPCYNKEGHHHKMTKLGLGLDDIASSDKE---ENPQESRRKSIQRCISSLVHACQCR 1692
            DLC+ CYN + H HKM K GLGLDD  SS  E   ++PQESRR SIQRCI SLVHACQCR
Sbjct: 1728 DLCINCYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCR 1787

Query: 1693 NANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCCYHAKHCVENKCQVPFCAXX 1752
            NANC + +C KMKRVV HT  C+RKTN GCP+CKQLIALCCYHAKHC ENKC VPFC   
Sbjct: 1788 NANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNI 1847

Query: 1753 XXXXXXXXXXTTLHQAQMLRRRVAIM 1778
                        L QAQ++RRR+A M
Sbjct: 1848 KHNVRQQQIQHCLQQAQLMRRRMATM 1873

 Score =  265 bits (677), Expect = 7e-69
 Identities = 183/377 (48%), Positives = 221/377 (58%), Gaps = 60/377 (15%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKGKSCEV 337
           +P+K KLIQQQLVLLLHAHKCQRREQ N E + C LP+CRTMKNVLNHMT C   K+C+V
Sbjct: 346 DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQV 405

Query: 338 AHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRNTQ-----------------GQSVNQ 379
           AHCASSRQII+HWKNC R DCPVC  LK A DKRN Q                 G     
Sbjct: 406 AHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQN 465

Query: 380 TSTMTAPNAADPATMKRAFESLGLQY-NQ-----------NTPAHNAAQHGHPQMNAMQN 427
            ++++ PN  DP++M+RA+ +LGL Y NQ             PA   A      +NA+ N
Sbjct: 466 ATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPPAHQQMRTLNALGN 525

Query: 428 DAGQINKTNM-PNQQGPKVVPDQXXXXXXXXXXXXTGQLPQTIQPQSGTQLXXXXXXXXX 486
           +   +    +  +QQ P ++ +                LP ++   +   L         
Sbjct: 526 NPMSVPAGGITTDQQPPNLISES--------------ALPTSL--GATNPLMNDGSNSGN 569

Query: 487 XXXXPDIVKSIPVSS---RKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLV 543
                 I  + P SS   RK WH +VTQDLR+HLVHKLVQAIFPTPD A L+D RM+NLV
Sbjct: 570 IGSLSTIPTAAPPSSTGVRKGWHERVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLV 629

Query: 544 AYARKVEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQ----NAPNAQVPGM 599
           AYA+KVEGDMYESAN+R +YYHLLAEKIYKIQKELEEKR  R+  Q    N P     G 
Sbjct: 630 AYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPALPASGA 689

Query: 600 QGQIHPNAQ-----NGP 611
           Q  + P AQ     NGP
Sbjct: 690 QPPVIPPAQSVRPPNGP 706

 Score = 43.5 bits (101), Expect = 0.052
 Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 12/91 (13%)

Query: 280  PDKSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAH 339
            P +S+ +  Q  +    H CQ R  N     C LP C+ MK V+ H   C +  +     
Sbjct: 1765 PQESRRLSIQRCIQSLVHACQCRNAN-----CSLPSCQKMKRVVQHTKGCKRKTN---GG 1816

Query: 340  CASSRQIIT----HWKNCLRQDCPVCFALKI 366
            C   +Q+I     H K+C    CPV F L I
Sbjct: 1817 CPVCKQLIALCCYHAKHCQENKCPVPFCLNI 1847
>gi|1345703|sp|P45481|CBP_MOUSE CREB-binding protein
 gi|481698|pir||S39161 CREB-binding protein - mouse
 gi|435855|gb|AAB28651.1| CREB-binding protein; CBP [Mus sp.]
          Length = 2441

 Score =  999 bits (2584), Expect = 0.0
 Identities = 522/866 (60%), Positives = 626/866 (72%), Gaps = 28/866 (3%)

Query: 921  KSESEVKPEPDSIKAENETSSPKLDNLDESSQASIEEKPASVGDASNNSAASTPKPRC-- 978
            +  S+VK E D+ + ++E        ++E       E      ++SN++A+ +  P    
Sbjct: 1028 QGSSQVKEETDTTEQKSEPME-----VEEKKPEVKVEAKEEEENSSNDTASQSTSPSQPR 1082

Query: 979  KKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPMDLSTIRRK 1038
            KK+F  +ELRQALMPTLE L++QDPESLPFRQPVDP +L IPDYFDIVK PMDLSTI+RK
Sbjct: 1083 KKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRK 1142

Query: 1039 LDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVMQSLGYCCG 1098
            LD+G Y +PW+YVDDV LMF+NAWLYNRKTSRVYK+ SKL+EVFE EID VMQSLGYCCG
Sbjct: 1143 LDTGQYQEPWQYVDDVRLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCG 1202

Query: 1099 HKYVFCPQVLCCYGKQLCTIPRDSMYYSYQNRYVYCEKCFNEIQTDEVELSEDPTQPMTK 1158
             KY F PQ LCCYGKQLCTIPRD+ YYSYQNRY +C KCF EIQ + V L +DP+QP T 
Sbjct: 1203 RKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCGKCFTEIQGENVTLGDDPSQPQTT 1262

Query: 1159 IRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREGWSCDSCLKAKGVKRKE 1218
            I KDQF++ KND LD EPF+DC+ECGR+ HQIC L ++ IW  G+ CD+CLK  G  RKE
Sbjct: 1263 ISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKE 1322

Query: 1219 NKFTSKKLPTTKLGTYLENRVNNFLRKKD-SGAGEVTIRVLSSYDKMTEVKPLMKKRF-- 1275
            NKF++K+L TT+LG +LE+RVN FLR+++   AGEV +RV++S DK  EVKP MK RF  
Sbjct: 1323 NKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVD 1382

Query: 1276 GNDMEDSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISYLDSVHFFK 1335
              +M +S+PYR KA+FAFEEIDGVDVCFFGMHVQ+     P      VYISYLDS+HFF+
Sbjct: 1383 SGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQDTALIAPHQIQGCVYISYLDSIHFFR 1442

Query: 1336 PRHLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQE 1395
            PR LRTAVYHEILIGYLEY K L Y TAHIWACPPSEGDDYIFHCHPP+QKIPKPKRLQE
Sbjct: 1443 PRCLRTAVYHEILIGYLEYVKKLVYVTAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQE 1502

Query: 1396 WYKKMLDKAIIDRVVVDYKDIFKDAIDSGISSAKDLAYFEGDFWPNVIEESIKELDQXXX 1455
            WYKKMLDKA  +R++ DYKDIFK A +  ++SAK+L YFEGDFWPNV+EESI        
Sbjct: 1503 WYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESI-------- 1554

Query: 1456 XXXXXXXXXXXXXXXXXQDTVEETTDAVCSDVAGTXXXXXXXXXXXXANKSKGSARKNNR 1515
                                  ET +    D                ++ S    R N +
Sbjct: 1555 ---KELEQEEEERKKEESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSIS----RANKK 1607

Query: 1516 KTNLPQGTNDLTAKLYNHMEKHKEVFFVIRLHNQQIAASLPPITEPDPAMSCELMDGRDA 1575
            K ++P  +NDL+ KLY  MEKHKEVFFVI LH   + ++ PPI +PDP +SC+LMDGRDA
Sbjct: 1608 KPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDA 1667

Query: 1576 FLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCNSCKAAVETRYHCSTCDDF 1635
            FLT AR+KH+EFSSLRR+K S++ +L ELH QG+D FVYTCN CK  VETR+HC+ C+D+
Sbjct: 1668 FLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDY 1727

Query: 1636 DLCVPCYNKEGHHHKMTKLGLGLDDIASSDKE---ENPQESRRKSIQRCISSLVHACQCR 1692
            DLC+ CYN + H HKM K GLGLDD  SS  E   ++PQESRR SIQRCI SLVHACQCR
Sbjct: 1728 DLCINCYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCR 1787

Query: 1693 NANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCCYHAKHCVENKCQVPFCAXX 1752
            NANC + +C KMKRVV HT  C+RKTN GCP+CKQLIALCCYHAKHC ENKC VPFC   
Sbjct: 1788 NANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNI 1847

Query: 1753 XXXXXXXXXXTTLHQAQMLRRRVAIM 1778
                        L QAQ++RRR+A M
Sbjct: 1848 KHNVRQQQIQHCLQQAQLMRRRMATM 1873

 Score =  265 bits (676), Expect = 9e-69
 Identities = 183/377 (48%), Positives = 220/377 (58%), Gaps = 60/377 (15%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKGKSCEV 337
           +P+K KLIQQQLVLLLHAHKCQRREQ N E + C LP+CRTMKNVLNHMT C   K+C+V
Sbjct: 346 DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAPKACQV 405

Query: 338 AHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRNTQ-----------------GQSVNQ 379
           AHCASSRQII+HWKNC R DCPVC  LK A DKRN Q                 G     
Sbjct: 406 AHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQN 465

Query: 380 TSTMTAPNAADPATMKRAFESLGLQY-NQ-----------NTPAHNAAQHGHPQMNAMQN 427
            ++++ PN  DP++M+RA+ +LGL Y NQ             PA   A      +NA+ N
Sbjct: 466 ATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPPAHQQMRTLNALGN 525

Query: 428 DAGQINKTNM-PNQQGPKVVPDQXXXXXXXXXXXXTGQLPQTIQPQSGTQLXXXXXXXXX 486
           +   +    +  +QQ P ++ +                LP ++   +   L         
Sbjct: 526 NPMSVPAGGITTDQQPPNLISES--------------ALPTSL--GATNPLMNDGSNSGN 569

Query: 487 XXXXPDIVKSIPVSS---RKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLV 543
                 I  + P SS   RK WH  VTQDLR+HLVHKLVQAIFPTPD A L+D RM+NLV
Sbjct: 570 IGSLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLV 629

Query: 544 AYARKVEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQ----NAPNAQVPGM 599
           AYA+KVEGDMYESAN+R +YYHLLAEKIYKIQKELEEKR  R+  Q    N P     G 
Sbjct: 630 AYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRTRLHKQGILGNQPALPASGA 689

Query: 600 QGQIHPNAQ-----NGP 611
           Q  + P AQ     NGP
Sbjct: 690 QPPVIPPAQSVRPPNGP 706

 Score = 43.5 bits (101), Expect = 0.052
 Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 12/91 (13%)

Query: 280  PDKSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAH 339
            P +S+ +  Q  +    H CQ R  N     C LP C+ MK V+ H   C +  +     
Sbjct: 1765 PQESRRLSIQRCIQSLVHACQCRNAN-----CSLPSCQKMKRVVQHTKGCKRKTN---GG 1816

Query: 340  CASSRQIIT----HWKNCLRQDCPVCFALKI 366
            C   +Q+I     H K+C    CPV F L I
Sbjct: 1817 CPVCKQLIALCCYHAKHCQENKCPVPFCLNI 1847
>gi|27663074|ref|XP_235502.1| similar to E1A-associated protein p300 [Rattus norvegicus]
          Length = 2156

 Score =  994 bits (2570), Expect = 0.0
 Identities = 532/911 (58%), Positives = 629/911 (69%), Gaps = 65/911 (7%)

Query: 917  MDTGKSESEVKPEPDSIKAENETSSPKLDNLDESSQASIEEKPASVGDASNNSAASTPKP 976
            MD  + E       D+ +A+ E    +    +E       E        S ++A S+P P
Sbjct: 621  MDVDQPEPADAQPDDTKEAKAEDGKVEPTETEERGPELKTEVKEEEDQPSTSAAQSSPAP 680

Query: 977  --RCKKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPMDLST 1034
                KK+F  +ELRQALMPTLE L++QDPESLPFRQPVDP +L IPDYFDIVK PMDLST
Sbjct: 681  GQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLST 740

Query: 1035 IRRKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVMQSLG 1094
            I+RKLD+G Y +PW+Y+DD+ LMF+NAWLYNRKTSRVYKY SKLSEVFE EID VMQSLG
Sbjct: 741  IKRKLDTGQYQEPWQYIDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLG 800

Query: 1095 YCCGHKYV------------FCPQVLCCYGKQLCTIPRDSMYYSYQNRYVYCEKCFNEIQ 1142
            YCCG K              F PQ LCCYGKQLCTIPRD+ YYSYQNRY +CEKCFNEIQ
Sbjct: 801  YCCGRKVFALLNKYFLLQLEFSPQTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQ 860

Query: 1143 TDEVELSEDPTQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREG 1202
             + V L +DP+QP T I K+QF + KND LD E F++C ECGR+ HQIC L  E IW  G
Sbjct: 861  GESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEVIWPSG 920

Query: 1203 WSCDSCLKAKGVKRKENKFTSKKLPTTKLGTYLENRVNNFLRKKD-SGAGEVTIRVLSSY 1261
            + CD CLK     RKENKF++K+LP+T+LGT+LENRVN+FLR+++   +GEVT+RV+ + 
Sbjct: 921  FVCDGCLKKTARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHAS 980

Query: 1262 DKMTEVKPLMKKRF----------------GNDMEDSYPYRAKAMFAFEEIDGVDVCFFG 1305
            DK  EVKP MK R                   +M +S+PYR KA+FAFEEIDGVD+CFFG
Sbjct: 981  DKTVEVKPGMKARCLVISHSLLTDLQLFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFG 1040

Query: 1306 MHVQEYGSSCPGPNTRRVYISYLDSVHFFKPRHLRTAVYHEILIGYLEYAKTLGYTTAHI 1365
            MHVQEYGS CP PN RRVYISYLDSVHFF+P+ LRTAVYHEILIGYLEY K LGYTT HI
Sbjct: 1041 MHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHI 1100

Query: 1366 WACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKDAIDSGI 1425
            WACPPSEGDDYIFHCHPP+QKIPKPKRLQEWYKKMLDKA+ +R+V DYKDI K A +  +
Sbjct: 1101 WACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDILKQATEDRL 1160

Query: 1426 SSAKDLAYFEGDFWPNVIEESIKELDQXXXXXXXXXXXXXXXXXXXXQDTVEETTDAVCS 1485
            +SAK+L YFEGDFWPNV+EESI                         ++T  E+TD    
Sbjct: 1161 TSAKELPYFEGDFWPNVLEESI------------KELEQEEEERKREENTSNESTDVTKG 1208

Query: 1486 DVAGTXXXXXXXXXXXXANKSKGSARKNNRKTNLPQGTNDLTAKLYNHMEKHKE------ 1539
            D                ++ S+G    N +K  +P  +NDL+ KLY  MEKHKE      
Sbjct: 1209 DSKNAKKKNNKKTSKNKSSLSRG----NKKKPGVPNVSNDLSQKLYATMEKHKEWHYSSR 1264

Query: 1540 ---------VFFVIRLHNQQIAASLPPITEPDPAMSCELMDGRDAFLTTAREKHYEFSSL 1590
                     VFFVIRL       SLPPI +PDP + C+LMDGRDAFLT AR+KH EFSSL
Sbjct: 1265 VTVSLVCWQVFFVIRLIACPAPNSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSL 1324

Query: 1591 RRAKLSSMALLYELHNQGKDAFVYTCNSCKAAVETRYHCSTCDDFDLCVPCYNKEGHHHK 1650
            RRA+ S+M +L ELH Q +D FVYTCN CK  VETR+HC+ C+D+DLC+ CYN + H HK
Sbjct: 1325 RRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHK 1384

Query: 1651 MTKLGLGLDDIASSDK---EENPQESRRKSIQRCISSLVHACQCRNANCRMNACHKMKRV 1707
            M KLGLGLDD +++ +    ++P +SRR SIQRCI SLVHACQCRNANC + +C KMKRV
Sbjct: 1385 MEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRV 1444

Query: 1708 VGHTMSCRRKTNNGCPICKQLIALCCYHAKHCVENKCQVPFCAXXXXXXXXXXXXTTLHQ 1767
            V HT  C+RKTN GCPICKQLIALCCYHAKHC ENKC VPFC               L Q
Sbjct: 1445 VQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQ 1504

Query: 1768 AQMLRRRVAIM 1778
            AQMLRRR+A M
Sbjct: 1505 AQMLRRRMASM 1515

 Score =  231 bits (590), Expect = 1e-58
 Identities = 147/311 (47%), Positives = 173/311 (55%), Gaps = 48/311 (15%)

Query: 319 MKNVLNHMTTCNKGKSCEVAHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRNTQ---- 373
           MKNVLNHMT C  GKSC+VAHCASSRQII+HWKNC R DCPVC  LK A DKRN Q    
Sbjct: 1   MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQSILT 60

Query: 374 ------------GQSVNQTSTMTAPNAADPATMKRAFESLGLQYNQNT-----PAHNAAQ 416
                       G     T +++  +  DP++++RA+ +LGL Y  N      P     Q
Sbjct: 61  GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQIPPQPPVQAKNQ 120

Query: 417 HGHPQMNAMQNDAGQINKTNMP-------NQQGPKVVPDQXXXXXXXXXXXXTGQLPQTI 469
              P   + Q      N +  P         Q P ++ D                L  TI
Sbjct: 121 QSQPSGQSPQGMRSMNNMSASPMGVNGGVGVQTPNLLSDS--------------MLHSTI 166

Query: 470 QPQSGTQLXXXXXXXXXXXXXPDIVKSIPVSSRKDWHAQVTQDLRNHLVHKLVQAIFPTP 529
             Q+   +             P   +      RK WH  +TQDLRNHLVHKLVQAIFPTP
Sbjct: 167 NSQN--PMMNENASVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTP 224

Query: 530 DQATLRDSRMKNLVAYARKVEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQ 589
           D A L+D RM+NLVAYARKVEGDMYESANNR +YYHLLAEKIYKIQKELEEKR  R++ Q
Sbjct: 225 DPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQ 284

Query: 590 NA-PNAQVPGM 599
           N  P+A  PGM
Sbjct: 285 NMLPSA--PGM 293

 Score = 43.1 bits (100), Expect = 0.061
 Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 12/95 (12%)

Query: 276  AAGEPDKSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSC 335
            A   P  S+ +  Q  +    H CQ R  N     C LP C+ MK V+ H   C +  + 
Sbjct: 1403 ATQSPGDSRRLSIQRCIQSLVHACQCRNAN-----CSLPSCQKMKRVVQHTKGCKRKTN- 1456

Query: 336  EVAHCASSRQIIT----HWKNCLRQDCPVCFALKI 366
                C   +Q+I     H K+C    CPV F L I
Sbjct: 1457 --GGCPICKQLIALCCYHAKHCQENKCPVPFCLNI 1489
>gi|27666550|ref|XP_235770.1| similar to E1A-associated protein p300 [Rattus norvegicus]
          Length = 1605

 Score =  950 bits (2456), Expect = 0.0
 Identities = 506/894 (56%), Positives = 592/894 (66%), Gaps = 98/894 (10%)

Query: 917  MDTGKSESEVKPEPDSIKAENETSSPKLDNLDESSQASIEEKPASVGDASNNSAASTPKP 976
            MD  + E       D+ +A+ E    +    +E       E        S ++A S+P P
Sbjct: 479  MDVDQPEPADAQPDDTKEAKAEDGKVEPTETEERGPELKTEVKEEEDQPSTSAAQSSPAP 538

Query: 977  --RCKKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPMDLST 1034
                KK+F  +ELRQALMPTLE L++QDPESLPFRQPVDP +L IPDYFDIVK PMDLST
Sbjct: 539  GQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLST 598

Query: 1035 IRRKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVMQSLG 1094
            I+RKLD+G Y +PW+Y+DD+ LMF+NAWLYNRKTSRVYKY SKLSEVFE EID VMQSLG
Sbjct: 599  IKRKLDTGQYQEPWQYIDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLG 658

Query: 1095 YCCGHKYV------------FCPQVLCCYGKQLCTIPRDSMYYSYQNRYVYCEKCFNEIQ 1142
            YCCG K              F PQ LCCYGKQLCTIPRD+ YYSYQNRY +CEKCFNEIQ
Sbjct: 659  YCCGRKVFALLNKYFLLQLEFSPQTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQ 718

Query: 1143 TDEVELSEDPTQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREG 1202
             + V L +DP+QP T I K+QF + KND LD E F++C ECGR+ HQIC L  E IW  G
Sbjct: 719  GESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEVIWPSG 778

Query: 1203 WSCDSCLKAKGVKRKENKFTSKKLPTTKLGTYLENRVNNFLRKKDSGAGEVTIRVLSSYD 1262
            + CD CLK     RKENKF++K+LP+T+LGT+LENR                        
Sbjct: 779  FVCDGCLKKTARTRKENKFSAKRLPSTRLGTFLENR------------------------ 814

Query: 1263 KMTEVKPLMKKRFGNDMEDSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNTRR 1322
                                      A+FAFEEIDGVD+CFFGMHVQEYGS CP PN RR
Sbjct: 815  --------------------------ALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRR 848

Query: 1323 VYISYLDSVHFFKPRHLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHCHP 1382
            VYISYLDSVHFF+P+ LRTAVYHEILIGYLEY K LGYTT HIWACPPSEGDDYIFHCHP
Sbjct: 849  VYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHP 908

Query: 1383 PEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKDAIDSGISSAKDLAYFEGDFWPNV 1442
            P+QKIPKPKRLQEWYKKMLDKA+ +R+V DYKDI K A +  ++SAK+L YFEGDFWPNV
Sbjct: 909  PDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDILKQATEDRLTSAKELPYFEGDFWPNV 968

Query: 1443 IEESIKELDQXXXXXXXXXXXXXXXXXXXXQDTVEETTDAVCSDVAGTXXXXXXXXXXXX 1502
            +EESI                         ++T  E+TD    D                
Sbjct: 969  LEESI------------KELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKNK 1016

Query: 1503 ANKSKGSARKNNRKTNLPQGTNDLTAKLYNHMEKHKE---------------VFFVIRLH 1547
            ++ S+G    N +K  +P  +NDL+ KLY  MEKHKE               VFFVIRL 
Sbjct: 1017 SSLSRG----NKKKPGVPNVSNDLSQKLYATMEKHKEWHYSSRVTVSLVCWQVFFVIRLI 1072

Query: 1548 NQQIAASLPPITEPDPAMSCELMDGRDAFLTTAREKHYEFSSLRRAKLSSMALLYELHNQ 1607
                  SLPPI +PDP + C+LMDGRDAFLT AR+KH EFSSLRRA+ S+M +L ELH Q
Sbjct: 1073 ACPAPNSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQ 1132

Query: 1608 GKDAFVYTCNSCKAAVETRYHCSTCDDFDLCVPCYNKEGHHHKMTKLGLGLDDIASSDK- 1666
             +D FVYTCN CK  VETR+HC+ C+D+DLC+ CYN + H HKM KLGLGLDD +++ + 
Sbjct: 1133 SQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQA 1192

Query: 1667 --EENPQESRRKSIQRCISSLVHACQCRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPI 1724
               ++P +SRR SIQRCI SLVHACQCRNANC + +C KMKRVV HT  C+RKTN GCPI
Sbjct: 1193 AATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPI 1252

Query: 1725 CKQLIALCCYHAKHCVENKCQVPFCAXXXXXXXXXXXXTTLHQAQMLRRRVAIM 1778
            CKQLIALCCYHAKHC ENKC VPFC               L QAQMLRRR+A M
Sbjct: 1253 CKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASM 1306

 Score =  235 bits (600), Expect = 6e-60
 Identities = 147/311 (47%), Positives = 173/311 (55%), Gaps = 48/311 (15%)

Query: 319 MKNVLNHMTTCNKGKSCEVAHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRNTQ---- 373
           MKNVLNHMT C  GKSC+VAHCASSRQII+HWKNC R DCPVC  LK A DKRN Q    
Sbjct: 1   MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQSILT 60

Query: 374 ------------GQSVNQTSTMTAPNAADPATMKRAFESLGLQYNQNT-----PAHNAAQ 416
                       G     T +++  +  DP++++RA+ +LGL Y  N      P     Q
Sbjct: 61  GAPVGLGNPSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQIPPQPPVQAKNQ 120

Query: 417 HGHPQMNAMQNDAGQINKTNMP-------NQQGPKVVPDQXXXXXXXXXXXXTGQLPQTI 469
              P   + Q      N +  P         Q P ++ D                L  TI
Sbjct: 121 QSQPSGQSPQGMRSMNNMSASPMGVNGGVGVQTPNLLSDS--------------MLHSTI 166

Query: 470 QPQSGTQLXXXXXXXXXXXXXPDIVKSIPVSSRKDWHAQVTQDLRNHLVHKLVQAIFPTP 529
             Q+   +             P   +      RK WH  +TQDLRNHLVHKLVQAIFPTP
Sbjct: 167 NSQN--PMMNENASVASLGPLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTP 224

Query: 530 DQATLRDSRMKNLVAYARKVEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQ 589
           D A L+D RM+NLVAYARKVEGDMYESANNR +YYHLLAEKIYKIQKELEEKR  R++ Q
Sbjct: 225 DPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQ 284

Query: 590 NA-PNAQVPGM 599
           N  P+A  PGM
Sbjct: 285 NMLPSA--PGM 293

 Score = 43.9 bits (102), Expect = 0.032
 Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 12/95 (12%)

Query: 276  AAGEPDKSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSC 335
            A   P  S+ +  Q  +    H CQ R  N     C LP C+ MK V+ H   C +  + 
Sbjct: 1194 ATQSPGDSRRLSIQRCIQSLVHACQCRNAN-----CSLPSCQKMKRVVQHTKGCKRKTN- 1247

Query: 336  EVAHCASSRQIIT----HWKNCLRQDCPVCFALKI 366
                C   +Q+I     H K+C    CPV F L I
Sbjct: 1248 --GGCPICKQLIALCCYHAKHCQENKCPVPFCLNI 1280
>gi|31753089|gb|AAH53889.1| Unknown (protein for IMAGE:6151364) [Homo sapiens]
          Length = 1553

 Score =  712 bits (1839), Expect = 0.0
 Identities = 359/534 (67%), Positives = 422/534 (79%), Gaps = 15/534 (2%)

Query: 927  KPEPDSIKAENETSSPKLDNLDESSQASIEEKPASV--------GDASNNSAASTPKP-- 976
            +PEP   + E+ + S   D   ES++   EE+   +           S ++  S+P P  
Sbjct: 986  QPEPADTQPEDISESKVEDCKMESTET--EERSTELKTEIKEEEDQPSTSATQSSPAPGQ 1043

Query: 977  RCKKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPMDLSTIR 1036
              KK+F  +ELRQALMPTLE L++QDPESLPFRQPVDP +L IPDYFDIVK PMDLSTI+
Sbjct: 1044 SKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIK 1103

Query: 1037 RKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVMQSLGYC 1096
            RKLD+G Y +PW+YVDD+ LMF+NAWLYNRKTSRVYKY SKLSEVFE EID VMQSLGYC
Sbjct: 1104 RKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYC 1163

Query: 1097 CGHKYVFCPQVLCCYGKQLCTIPRDSMYYSYQNRYVYCEKCFNEIQTDEVELSEDPTQPM 1156
            CG K  F PQ LCCYGKQLCTIPRD+ YYSYQNRY +CEKCFNEIQ + V L +DP+QP 
Sbjct: 1164 CGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQ 1223

Query: 1157 TKIRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREGWSCDSCLKAKGVKR 1216
            T I K+QF + KND LD E F++C ECGR+ HQIC L  E IW  G+ CD CLK     R
Sbjct: 1224 TTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTR 1283

Query: 1217 KENKFTSKKLPTTKLGTYLENRVNNFLRKKD-SGAGEVTIRVLSSYDKMTEVKPLMKKRF 1275
            KENKF++K+LP+T+LGT+LENRVN+FLR+++   +GEVT+RV+ + DK  EVKP MK RF
Sbjct: 1284 KENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARF 1343

Query: 1276 --GNDMEDSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISYLDSVHF 1333
                +M +S+PYR KA+FAFEEIDGVD+CFFGMHVQEYGS CP PN RRVYISYLDSVHF
Sbjct: 1344 VDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHF 1403

Query: 1334 FKPRHLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRL 1393
            F+P+ LRTAVYHEILIGYLEY K LGYTT HIWACPPSEGDDYIFHCHPP+QKIPKPKRL
Sbjct: 1404 FRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRL 1463

Query: 1394 QEWYKKMLDKAIIDRVVVDYKDIFKDAIDSGISSAKDLAYFEGDFWPNVIEESI 1447
            QEWYKKMLDKA+ +R+V DYKDIFK A +  ++SAK+L YFEGDFWPNV+EESI
Sbjct: 1464 QEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESI 1517

 Score =  269 bits (688), Expect = 5e-70
 Identities = 176/360 (48%), Positives = 206/360 (57%), Gaps = 42/360 (11%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKGKSCEV 337
           +P+K KLIQQQLVLLLHAHKCQRREQ N E ++C LP+CRTMKNVLNHMT C  GKSC+V
Sbjct: 331 DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQV 390

Query: 338 AHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRNTQ-----------GQSVNQTSTMTA 385
           AHCASSRQII+HWKNC R DCPVC  LK A DKRN Q             S       +A
Sbjct: 391 AHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNPSSLGVGQQSA 450

Query: 386 PNAA-----DPATMKRAFESLGLQYNQNTPAHNAAQHGHPQMNAMQNDAGQINKTNMPNQ 440
           PN +     DP++++RA+ +LGL Y  N            QM        +  +   P Q
Sbjct: 451 PNLSTVSQIDPSSIERAYAALGLPYQVN------------QMPTQPQVQAKNQQNQQPGQ 498

Query: 441 QGPKVVPDQXXXXXXXXXXXXTG-QLPQTIQP-------QSGTQLXXXXXXXXXXXXXPD 492
               + P               G Q P  +          S   +             P 
Sbjct: 499 SPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQNPMMSENASVPSLGPMPT 558

Query: 493 IVKSIPVSSRKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARKVEGD 552
             +      RK WH  +TQDLRNHLVHKLVQAIFPTPD A L+D RM+NLVAYARKVEGD
Sbjct: 559 AAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGD 618

Query: 553 MYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQNAPNAQVPGMQGQIHPNAQNGPN 612
           MYESANNR +YYHLLAEKIYKIQKELEEKR  R++ QN     +P   G +  +   GPN
Sbjct: 619 MYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQN----MLPNAAGMVPVSMNPGPN 674
>gi|2133462|pir||S60123 hypothetical protein R10E11.1 - Caenorhabditis elegans
          Length = 2027

 Score =  545 bits (1403), Expect = e-153
 Identities = 280/566 (49%), Positives = 376/566 (66%), Gaps = 34/566 (6%)

Query: 917  MDTGKSESEVKPEPDSI---KAENETSSPKLDNL---DESSQASIEEKPASVGDASNNSA 970
            MD   ++S     P +I    + + T +P ++ +   +E  + S  + P SV D  +  A
Sbjct: 782  MDDQNTDSLSSRPPTAIGFGGSSSSTPAPIMNGIVKKEEDPEESSNQAPPSVKDTKDGVA 841

Query: 971  ASTPK-----------PRCKKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHI 1019
             S PK           P    VF +++L + L+P  EKL K + ++ PFR PVD  +L+I
Sbjct: 842  ESKPKEQQAKREPTPPPTEDTVFSQEDLIKFLLPVWEKLDKSE-DAAPFRVPVDAKLLNI 900

Query: 1020 PDYFDIVKKPMDLSTIRRKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLS 1079
            PDY +I+K+PMDL T+ +KL +G Y +  ++ DD+ LM DNAWLYNRK S+VYKY  KLS
Sbjct: 901  PDYHEIIKRPMDLETVHKKLYAGQYQNAGQFCDDIWLMLDNAWLYNRKNSKVYKYGLKLS 960

Query: 1080 EVFESEIDSVMQSLGYCCGHKYVFCPQVLCCYGKQLCTIPRDSMYYSYQN---------- 1129
            E+F SE+D VM+S+GYCC  K  F P  L CYG  +CTI R+  Y+ ++           
Sbjct: 961  EMFVSEMDPVMKSMGYCCAKKLAFTPLSLFCYGAAMCTIAREQQYWVFEQSSTQYNVTVT 1020

Query: 1130 -RYVYCEKCFNEIQTDEVELSEDPTQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWH 1188
             RY YC+KCF+ +  + + LSE+P        K  F   KN  +DYEPF  C+ C R+WH
Sbjct: 1021 ERYTYCQKCFDALPPEGISLSENPNDRNNMAPKTSFTEQKNSVIDYEPFERCKYCMRKWH 1080

Query: 1189 QICALWFESIWREGWSCDSCLKAKGVKRKENKFTSKKLPTTKLGTYLENRVNNFLRKK-- 1246
            +ICAL  + ++ EG+ C+ C  AK  ++ +NK+ + KLP  KL T+LE+RVN F++K+  
Sbjct: 1081 RICALHDKKVYPEGFICECCRTAKKYQKPDNKYLASKLPHNKLSTFLEDRVNGFIKKQLQ 1140

Query: 1247 -DSGAGEVTIRVLSSYDKMTEVKPLMKKRF--GNDMEDSYPYRAKAMFAFEEIDGVDVCF 1303
             ++    V IR L   DK  EVK  MK+++   N   + +PYR KA+FAFE IDGV+VCF
Sbjct: 1141 AEAHKYPVIIRTLCVQDKEAEVKAQMKQKYVESNQFPEKFPYRTKAVFAFEIIDGVEVCF 1200

Query: 1304 FGMHVQEYGSSCPGPNTRRVYISYLDSVHFFKPRHLRTAVYHEILIGYLEYAKTLGYTTA 1363
            FG+HVQEYGS+CP PN RRVYI+YLDSVHFF+PR LRT VYHE+L+GYL+YAK LGYT A
Sbjct: 1201 FGLHVQEYGSACPAPNARRVYIAYLDSVHFFQPRELRTDVYHELLLGYLDYAKMLGYTMA 1260

Query: 1364 HIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKDAIDS 1423
            HIWACPPSEGDDYIFHCHPPEQKIPKPKRLQ+WYKKML+K + +  VV++KDI+K A D 
Sbjct: 1261 HIWACPPSEGDDYIFHCHPPEQKIPKPKRLQDWYKKMLEKGVQEGSVVEFKDIYKQARDD 1320

Query: 1424 GISSAKDLAYFEGDFWPNVIEESIKE 1449
             +++   L YFEGDFWPNVIE+ I+E
Sbjct: 1321 NLTTPTQLPYFEGDFWPNVIEDCIRE 1346

 Score = 99.4 bits (246), Expect = 6e-19
 Identities = 62/108 (57%), Positives = 70/108 (64%), Gaps = 21/108 (19%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE----------QECKLPYCRTMKNVLNHMTT 328
           +P+K KLIQQQLVLLLHAHKC +RE+ N +            C LP+C TMK VL HMT+
Sbjct: 399 DPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTS 458

Query: 329 CNKG-----------KSCEVAHCASSRQIITHWKNCLRQDCPVCFALK 365
           CN G           K C VAHCASSRQII HWKNC R+DCPVC  LK
Sbjct: 459 CNVGRLCHSDTTQTTKKCSVAHCASSRQIIAHWKNCSREDCPVCKPLK 506

 Score = 39.3 bits (90), Expect = 0.90
 Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 14/95 (14%)

Query: 286  IQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAHCASSRQ 345
            IQ+ +  L+HA  CQ R+ N     C+   C  MK V+ H   C K  +     C   +Q
Sbjct: 1557 IQRCIASLVHA--CQCRDAN-----CRRMSCHKMKRVVQHTKMCKKRIN---GTCPVCKQ 1606

Query: 346  IIT----HWKNCLRQDCPVCFALKIADKRNTQGQS 376
            +I     H K+C R  C V F + I  K   Q +S
Sbjct: 1607 LIALCCYHAKHCTRDACTVPFCMNIRQKLAEQKRS 1641
>gi|17552708|ref|NP_499161.1| CBP/p300 homolog (cbp-1) [Caenorhabditis elegans]
 gi|14530537|emb|CAA82353.2| C. elegans CBP-1 protein (corresponding sequence R10E11.1a)
            [Caenorhabditis elegans]
          Length = 2045

 Score =  544 bits (1402), Expect = e-153
 Identities = 280/566 (49%), Positives = 376/566 (66%), Gaps = 34/566 (6%)

Query: 917  MDTGKSESEVKPEPDSI---KAENETSSPKLDNL---DESSQASIEEKPASVGDASNNSA 970
            MD   ++S     P +I    + + T +P ++ +   +E  + S  + P SV D  +  A
Sbjct: 771  MDDQNTDSLSSRPPTAIGFGGSSSSTPAPIMNGIVKKEEDPEESSNQAPPSVKDTKDGVA 830

Query: 971  ASTPK-----------PRCKKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHI 1019
             S PK           P    VF +++L + L+P  EKL K + ++ PFR PVD  +L+I
Sbjct: 831  ESKPKEQQAKREPTPPPTEDTVFSQEDLIKFLLPVWEKLDKSE-DAAPFRVPVDAKLLNI 889

Query: 1020 PDYFDIVKKPMDLSTIRRKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLS 1079
            PDY +I+K+PMDL T+ +KL +G Y +  ++ DD+ LM DNAWLYNRK S+VYKY  KLS
Sbjct: 890  PDYHEIIKRPMDLETVHKKLYAGQYQNAGQFCDDIWLMLDNAWLYNRKNSKVYKYGLKLS 949

Query: 1080 EVFESEIDSVMQSLGYCCGHKYVFCPQVLCCYGKQLCTIPRDSMYYSYQN---------- 1129
            E+F SE+D VM+S+GYCC  K  F P  L CYG  +CTI R+  Y+ ++           
Sbjct: 950  EMFVSEMDPVMKSMGYCCAKKLAFTPLSLFCYGAAMCTIAREQQYWVFEQSSTQYNVTVT 1009

Query: 1130 -RYVYCEKCFNEIQTDEVELSEDPTQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWH 1188
             RY YC+KCF+ +  + + LSE+P        K  F   KN  +DYEPF  C+ C R+WH
Sbjct: 1010 ERYTYCQKCFDALPPEGISLSENPNDRNNMAPKTSFTEQKNSVIDYEPFERCKYCMRKWH 1069

Query: 1189 QICALWFESIWREGWSCDSCLKAKGVKRKENKFTSKKLPTTKLGTYLENRVNNFLRKK-- 1246
            +ICAL  + ++ EG+ C+ C  AK  ++ +NK+ + KLP  KL T+LE+RVN F++K+  
Sbjct: 1070 RICALHDKKVYPEGFICECCRTAKKYQKPDNKYLASKLPHNKLSTFLEDRVNGFIKKQLQ 1129

Query: 1247 -DSGAGEVTIRVLSSYDKMTEVKPLMKKRF--GNDMEDSYPYRAKAMFAFEEIDGVDVCF 1303
             ++    V IR L   DK  EVK  MK+++   N   + +PYR KA+FAFE IDGV+VCF
Sbjct: 1130 AEAHKYPVIIRTLCVQDKEAEVKAQMKQKYVESNQFPEKFPYRTKAVFAFEIIDGVEVCF 1189

Query: 1304 FGMHVQEYGSSCPGPNTRRVYISYLDSVHFFKPRHLRTAVYHEILIGYLEYAKTLGYTTA 1363
            FG+HVQEYGS+CP PN RRVYI+YLDSVHFF+PR LRT VYHE+L+GYL+YAK LGYT A
Sbjct: 1190 FGLHVQEYGSACPAPNARRVYIAYLDSVHFFQPRELRTDVYHELLLGYLDYAKMLGYTMA 1249

Query: 1364 HIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKDAIDS 1423
            HIWACPPSEGDDYIFHCHPPEQKIPKPKRLQ+WYKKML+K + +  VV++KDI+K A D 
Sbjct: 1250 HIWACPPSEGDDYIFHCHPPEQKIPKPKRLQDWYKKMLEKGVQEGSVVEFKDIYKQARDD 1309

Query: 1424 GISSAKDLAYFEGDFWPNVIEESIKE 1449
             +++   L YFEGDFWPNVIE+ I+E
Sbjct: 1310 NLTTPTQLPYFEGDFWPNVIEDCIRE 1335

 Score =  104 bits (259), Expect = 2e-20
 Identities = 60/97 (61%), Positives = 69/97 (71%), Gaps = 10/97 (10%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE----------QECKLPYCRTMKNVLNHMTT 328
           +P+K KLIQQQLVLLLHAHKC +RE+ N +            C LP+C TMK VL HMT+
Sbjct: 399 DPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTS 458

Query: 329 CNKGKSCEVAHCASSRQIITHWKNCLRQDCPVCFALK 365
           CN G+ C  AHCASSRQII HWKNC R+DCPVC  LK
Sbjct: 459 CNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCKPLK 495

 Score = 39.3 bits (90), Expect = 0.91
 Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 14/95 (14%)

Query: 286  IQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAHCASSRQ 345
            IQ+ +  L+HA  CQ R+ N     C+   C  MK V+ H   C K  +     C   +Q
Sbjct: 1546 IQRCIASLVHA--CQCRDAN-----CRRMSCHKMKRVVQHTKMCKKRIN---GTCPVCKQ 1595

Query: 346  IIT----HWKNCLRQDCPVCFALKIADKRNTQGQS 376
            +I     H K+C R  C V F + I  K   Q +S
Sbjct: 1596 LIALCCYHAKHCTRDACTVPFCMNIRQKLAEQKRS 1630
>gi|17552710|ref|NP_499160.1| CBP/p300 homolog (cbp-1) [Caenorhabditis elegans]
 gi|20455476|sp|P34545|CBP1_CAEEL Protein cbp-1
 gi|25299632|pir||G88564 protein R10E11.1 [imported] - Caenorhabditis elegans
 gi|17645979|emb|CAD18875.1| C. elegans CBP-1 protein (corresponding sequence R10E11.1b)
            [Caenorhabditis elegans]
          Length = 2056

 Score =  544 bits (1401), Expect = e-153
 Identities = 280/566 (49%), Positives = 376/566 (66%), Gaps = 34/566 (6%)

Query: 917  MDTGKSESEVKPEPDSI---KAENETSSPKLDNL---DESSQASIEEKPASVGDASNNSA 970
            MD   ++S     P +I    + + T +P ++ +   +E  + S  + P SV D  +  A
Sbjct: 782  MDDQNTDSLSSRPPTAIGFGGSSSSTPAPIMNGIVKKEEDPEESSNQAPPSVKDTKDGVA 841

Query: 971  ASTPK-----------PRCKKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHI 1019
             S PK           P    VF +++L + L+P  EKL K + ++ PFR PVD  +L+I
Sbjct: 842  ESKPKEQQAKREPTPPPTEDTVFSQEDLIKFLLPVWEKLDKSE-DAAPFRVPVDAKLLNI 900

Query: 1020 PDYFDIVKKPMDLSTIRRKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLS 1079
            PDY +I+K+PMDL T+ +KL +G Y +  ++ DD+ LM DNAWLYNRK S+VYKY  KLS
Sbjct: 901  PDYHEIIKRPMDLETVHKKLYAGQYQNAGQFCDDIWLMLDNAWLYNRKNSKVYKYGLKLS 960

Query: 1080 EVFESEIDSVMQSLGYCCGHKYVFCPQVLCCYGKQLCTIPRDSMYYSYQN---------- 1129
            E+F SE+D VM+S+GYCC  K  F P  L CYG  +CTI R+  Y+ ++           
Sbjct: 961  EMFVSEMDPVMKSMGYCCAKKLAFTPLSLFCYGAAMCTIAREQQYWVFEQSSTQYNVTVT 1020

Query: 1130 -RYVYCEKCFNEIQTDEVELSEDPTQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWH 1188
             RY YC+KCF+ +  + + LSE+P        K  F   KN  +DYEPF  C+ C R+WH
Sbjct: 1021 ERYTYCQKCFDALPPEGISLSENPNDRNNMAPKTSFTEQKNSVIDYEPFERCKYCMRKWH 1080

Query: 1189 QICALWFESIWREGWSCDSCLKAKGVKRKENKFTSKKLPTTKLGTYLENRVNNFLRKK-- 1246
            +ICAL  + ++ EG+ C+ C  AK  ++ +NK+ + KLP  KL T+LE+RVN F++K+  
Sbjct: 1081 RICALHDKKVYPEGFICECCRTAKKYQKPDNKYLASKLPHNKLSTFLEDRVNGFIKKQLQ 1140

Query: 1247 -DSGAGEVTIRVLSSYDKMTEVKPLMKKRF--GNDMEDSYPYRAKAMFAFEEIDGVDVCF 1303
             ++    V IR L   DK  EVK  MK+++   N   + +PYR KA+FAFE IDGV+VCF
Sbjct: 1141 AEAHKYPVIIRTLCVQDKEAEVKAQMKQKYVESNQFPEKFPYRTKAVFAFEIIDGVEVCF 1200

Query: 1304 FGMHVQEYGSSCPGPNTRRVYISYLDSVHFFKPRHLRTAVYHEILIGYLEYAKTLGYTTA 1363
            FG+HVQEYGS+CP PN RRVYI+YLDSVHFF+PR LRT VYHE+L+GYL+YAK LGYT A
Sbjct: 1201 FGLHVQEYGSACPAPNARRVYIAYLDSVHFFQPRELRTDVYHELLLGYLDYAKMLGYTMA 1260

Query: 1364 HIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKDAIDS 1423
            HIWACPPSEGDDYIFHCHPPEQKIPKPKRLQ+WYKKML+K + +  VV++KDI+K A D 
Sbjct: 1261 HIWACPPSEGDDYIFHCHPPEQKIPKPKRLQDWYKKMLEKGVQEGSVVEFKDIYKQARDD 1320

Query: 1424 GISSAKDLAYFEGDFWPNVIEESIKE 1449
             +++   L YFEGDFWPNVIE+ I+E
Sbjct: 1321 NLTTPTQLPYFEGDFWPNVIEDCIRE 1346

 Score = 99.4 bits (246), Expect = 7e-19
 Identities = 62/108 (57%), Positives = 70/108 (64%), Gaps = 21/108 (19%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE----------QECKLPYCRTMKNVLNHMTT 328
           +P+K KLIQQQLVLLLHAHKC +RE+ N +            C LP+C TMK VL HMT+
Sbjct: 399 DPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTS 458

Query: 329 CNKG-----------KSCEVAHCASSRQIITHWKNCLRQDCPVCFALK 365
           CN G           K C VAHCASSRQII HWKNC R+DCPVC  LK
Sbjct: 459 CNVGRLCHSDTTQTTKKCSVAHCASSRQIIAHWKNCSREDCPVCKPLK 506

 Score = 39.3 bits (90), Expect = 0.91
 Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 14/95 (14%)

Query: 286  IQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAHCASSRQ 345
            IQ+ +  L+HA  CQ R+ N     C+   C  MK V+ H   C K  +     C   +Q
Sbjct: 1557 IQRCIASLVHA--CQCRDAN-----CRRMSCHKMKRVVQHTKMCKKRIN---GTCPVCKQ 1606

Query: 346  IIT----HWKNCLRQDCPVCFALKIADKRNTQGQS 376
            +I     H K+C R  C V F + I  K   Q +S
Sbjct: 1607 LIALCCYHAKHCTRDACTVPFCMNIRQKLAEQKRS 1641
>gi|1888540|gb|AAC51340.1| CREB-binding protein [Homo sapiens]
          Length = 932

 Score =  374 bits (959), Expect = e-101
 Identities = 201/374 (53%), Positives = 242/374 (64%), Gaps = 18/374 (4%)

Query: 1408 RVVVDYKDIFKDAIDSGISSAKDLAYFEGDFWPNVIEESIKELDQXXXXXXXXXXXXXXX 1467
            R++ DYKDIFK A +  ++SAK+L YFEGDFWPNV+EESI                    
Sbjct: 4    RIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESI-----------KELEQEEEE 52

Query: 1468 XXXXXQDTVEETTDAVCSDVAGTXXXXXXXXXXXXANKSKGSARKNNRKTNLPQGTNDLT 1527
                      ETT+    D                ++ S    R N +K ++P  +NDL+
Sbjct: 53   RKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSIS----RANKKKPSMPNVSNDLS 108

Query: 1528 AKLYNHMEKHKEVFFVIRLHNQQIAASLPPITEPDPAMSCELMDGRDAFLTTAREKHYEF 1587
             KLY  MEKHKEVFFVI LH   +  +LPPI +PDP +SC+LMDGRDAFLT AR+KH+EF
Sbjct: 109  QKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEF 168

Query: 1588 SSLRRAKLSSMALLYELHNQGKDAFVYTCNSCKAAVETRYHCSTCDDFDLCVPCYNKEGH 1647
            SSLRR+K S++ +L ELH QG+D FVYTCN CK  VETR+HC+ C  +DLC+ CYN + H
Sbjct: 169  SSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCVVYDLCINCYNTKSH 228

Query: 1648 HHKMTKLGLGLDDIASSDKE---ENPQESRRKSIQRCISSLVHACQCRNANCRMNACHKM 1704
             HKM K GLGLDD  SS  E   ++PQESRR SIQRCI SLVHACQCRNA C + +C KM
Sbjct: 229  AHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNAFCSLPSCQKM 288

Query: 1705 KRVVGHTMSCRRKTNNGCPICKQLIALCCYHAKHCVENKCQVPFCAXXXXXXXXXXXXTT 1764
            KRVV HT  C+RK N GCP+CKQLIALCCYHAKHC ENKC VPFC               
Sbjct: 289  KRVVQHTKGCKRKPNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHR 348

Query: 1765 LHQAQMLRRRVAIM 1778
            L QAQ++RRR+A M
Sbjct: 349  LQQAQLMRRRMATM 362

 Score = 40.8 bits (94), Expect = 0.27
 Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 12/94 (12%)

Query: 280 PDKSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAH 339
           P +S+ +  Q  +    H CQ R        C LP C+ MK V+ H   C +  +     
Sbjct: 254 PQESRRLSIQRCIQSLVHACQCRNAF-----CSLPSCQKMKRVVQHTKGCKRKPN---GG 305

Query: 340 CASSRQIIT----HWKNCLRQDCPVCFALKIADK 369
           C   +Q+I     H K+C    CPV F L I  K
Sbjct: 306 CPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHK 339
>gi|28486618|ref|XP_128116.2| similar to E1A-associated protein p300 [Mus musculus]
          Length = 234

 Score =  324 bits (831), Expect = 1e-86
 Identities = 137/170 (80%), Positives = 153/170 (90%)

Query: 1278 DMEDSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISYLDSVHFFKPR 1337
            +M +S+PYR KA+FAFEEIDGVD+CFFGMHVQEYGS CP PN RRVYISYLDSVHFF+P+
Sbjct: 16   EMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPK 75

Query: 1338 HLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWY 1397
             LRTAVYHEILIGYLEY K LGYTT HIWACPPSEGDDYIFHCHPP+QKIPKPKRLQEWY
Sbjct: 76   CLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWY 135

Query: 1398 KKMLDKAIIDRVVVDYKDIFKDAIDSGISSAKDLAYFEGDFWPNVIEESI 1447
            KKMLDKA+ +R+V DYKDI K A +  ++SAK+L YFEGDFWPNV+EESI
Sbjct: 136  KKMLDKAVSERIVHDYKDILKQATEDRLTSAKELPYFEGDFWPNVLEESI 185
>gi|3168627|gb|AAC17736.1| CBP [Homo sapiens]
          Length = 923

 Score =  318 bits (816), Expect = 6e-85
 Identities = 157/243 (64%), Positives = 184/243 (75%), Gaps = 3/243 (1%)

Query: 1539 EVFFVIRLHNQQIAASLPPITEPDPAMSCELMDGRDAFLTTAREKHYEFSSLRRAKLSSM 1598
            EVFFVI LH   +  +LPPI +PDP +SC+LMDGRDAFLT AR+KH+EFSSLRR+K S++
Sbjct: 111  EVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTL 170

Query: 1599 ALLYELHNQGKDAFVYTCNSCKAAVETRYHCSTCDDFDLCVPCYNKEGHHHKMTKLGLGL 1658
             +L ELH QG+D FVYTCN CK  VETR+HC+ C+D+DLC+ CYN + H HKM K GLGL
Sbjct: 171  CMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWGLGL 230

Query: 1659 DDIASSDKE---ENPQESRRKSIQRCISSLVHACQCRNANCRMNACHKMKRVVGHTMSCR 1715
            DD  SS  E   ++PQESRR SIQRCI SLVHACQCRNANC + +C KMKRVV HT  C+
Sbjct: 231  DDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCK 290

Query: 1716 RKTNNGCPICKQLIALCCYHAKHCVENKCQVPFCAXXXXXXXXXXXXTTLHQAQMLRRRV 1775
            RKTN GCP+CKQLIALCCYHAKHC ENKC VPFC               L QAQ++RRR+
Sbjct: 291  RKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRM 350

Query: 1776 AIM 1778
            A M
Sbjct: 351  ATM 353

 Score =  153 bits (386), Expect = 4e-35
 Identities = 69/88 (78%), Positives = 78/88 (88%)

Query: 1360 YTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKD 1419
            Y T HIWACPPSEGDDYIFHCHPP+QKIPKPKRLQEWYKKMLDKA  +R++ DYKDIFK 
Sbjct: 1    YVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQ 60

Query: 1420 AIDSGISSAKDLAYFEGDFWPNVIEESI 1447
            A +  ++SAK+L YFEGDFWPNV+EESI
Sbjct: 61   ATEDRLTSAKELPYFEGDFWPNVLEESI 88

 Score = 44.7 bits (104), Expect = 0.022
 Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 12/94 (12%)

Query: 280 PDKSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAH 339
           P +S+ +  Q  +    H CQ R  N     C LP C+ MK V+ H   C +  +     
Sbjct: 245 PQESRRLSIQRCIQSLVHACQCRNAN-----CSLPSCQKMKRVVQHTKGCKRKTN---GG 296

Query: 340 CASSRQIIT----HWKNCLRQDCPVCFALKIADK 369
           C   +Q+I     H K+C    CPV F L I  K
Sbjct: 297 CPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHK 330
>gi|547239|gb|AAB31182.1| p300=transcription coactivator {N-terminal} [mice, Peptide Partial,
           688 aa]
          Length = 688

 Score =  286 bits (731), Expect = 5e-75
 Identities = 176/352 (50%), Positives = 209/352 (59%), Gaps = 49/352 (13%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKGKSCEV 337
           +P+K  +IQQQLVLLLHAHKCQRREQ N E ++C LP+CRTMKNVLNHMT C  GKSC+V
Sbjct: 332 DPEKRNVIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQV 391

Query: 338 AHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRN----------------TQGQSVNQT 380
           AHCASSRQII+HWKNC R DCPVC  LK A DKRN                + G     T
Sbjct: 392 AHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQCSILTGAPVGLGNPSSLGVGQQST 451

Query: 381 STMTAPNAADPATMKRAFESLGLQY--NQNTPAHNAAQHGHPQMNAMQNDAGQINKTNMP 438
            +++  +  DP++++RA+ +LGL Y  NQ  P             + Q+  G  +  NM 
Sbjct: 452 PSLSTVSQIDPSSIERAYAALGLPYQVNQIPPQPQVQAKNQQSQPSGQSPQGMRSVNNMS 511

Query: 439 NQ----------QGPKVVPDQXXXXXXXXXXXXTGQLPQTIQPQSGTQLXXXXXXXXXXX 488
                       Q P ++ D                L  TI  Q+   +           
Sbjct: 512 ASPMGVNGGVGVQTPNLLSDS--------------MLHSTINSQN--PMMSGNAGVASLG 555

Query: 489 XXPDIVKSIPVSSRKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARK 548
             P   +      RK WH  +TQDLRNHLVHKLVQAIFPTPD A L+D RM+NLVAYARK
Sbjct: 556 PLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARK 615

Query: 549 VEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQNA-PNAQVPGM 599
           VEGDMYESANNR +YYHLLAEKIYKIQKELEEKR  R++ QN  PNA  PGM
Sbjct: 616 VEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNA--PGM 665
>gi|28486616|ref|XP_283295.1| similar to E1A-associated protein p300 [Mus musculus]
 gi|29244384|ref|NP_808489.1| hypothetical protein A730011L11 [Mus musculus]
 gi|26335221|dbj|BAC31311.1| unnamed protein product [Mus musculus]
          Length = 714

 Score =  269 bits (687), Expect = 6e-70
 Identities = 179/352 (50%), Positives = 210/352 (59%), Gaps = 49/352 (13%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKGKSCEV 337
           +P+K KLIQQQLVLLLHAHKCQRREQ N E ++C LP+CRTMKNVLNHMT C  GKSC+V
Sbjct: 332 DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQV 391

Query: 338 AHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRNTQ----------------GQSVNQT 380
           AHCASSRQII+HWKNC R DCPVC  LK A DKRN Q                G     T
Sbjct: 392 AHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQSILTGAPVGLGNPSSLGVGQQST 451

Query: 381 STMTAPNAADPATMKRAFESLGLQY--NQNTPAHNAAQHGHPQMNAMQNDAGQINKTNMP 438
            +++  +  DP++++RA+ +LGL Y  NQ  P             + Q+  G  +  NM 
Sbjct: 452 PSLSTVSQIDPSSIERAYAALGLPYQVNQIPPQPQVQAKNQQSQPSGQSPQGMRSVNNMS 511

Query: 439 NQ----------QGPKVVPDQXXXXXXXXXXXXTGQLPQTIQPQSGTQLXXXXXXXXXXX 488
                       Q P ++ D                L  TI  Q+   +           
Sbjct: 512 ASPMGVNGGVGVQTPNLLSDS--------------MLHSTINSQN--PMMSENAGVASLG 555

Query: 489 XXPDIVKSIPVSSRKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARK 548
             P   +      RK WH  +TQDLRNHLVHKLVQAIFPTPD A L+D RM+NLVAYARK
Sbjct: 556 PLPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARK 615

Query: 549 VEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQNA-PNAQVPGM 599
           VEGDMYESANNR +YYHLLAEKIYKIQKELEEKR  R++ QN  PNA  PGM
Sbjct: 616 VEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNA--PGM 665
>gi|27881767|gb|AAH44677.1| Similar to CREB binding protein (Rubinstein-Taybi syndrome)
           [Xenopus laevis]
          Length = 1047

 Score =  266 bits (680), Expect = 3e-69
 Identities = 178/356 (50%), Positives = 213/356 (59%), Gaps = 43/356 (12%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKGKSCEV 337
           +P+K KLIQQQLVLLLHAHKCQRREQ N E ++C LP+CRTMKNVLNHMT C  GK+C+V
Sbjct: 344 DPEKRKLIQQQLVLLLHAHKCQRREQANGEMRDCSLPHCRTMKNVLNHMTHCQAGKACQV 403

Query: 338 AHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRN----------------TQGQSVNQT 380
           AHCASSRQII+HWKNC R DCPVC  LK A DKRN                T G      
Sbjct: 404 AHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQNLPVSLASGVQSPIGTTGGGQQTA 463

Query: 381 STMTAPNAADPATMKRAFESLGLQYN---QNTPAHNAAQHGHPQ---MNAMQNDAGQINK 434
            ++++PN  DP++M+RA+ +LGL Y    Q T    A    H Q   MNA+  +   +  
Sbjct: 464 PSLSSPNPIDPSSMQRAYAALGLPYGNPAQGTGQQPAQTQVHQQIRNMNALGGNQMNLTA 523

Query: 435 TNMPNQQGPKVVPDQXXXXXXXXXXXXTGQLPQTIQPQSGTQLXXXXXXXXXXXXXPDIV 494
             M  +Q   ++ D                LP  +   +   L               + 
Sbjct: 524 GGMTVEQQTNLISDT--------------ALPTAL--ANSNSLLSDGNGQSTVGNHGTMP 567

Query: 495 KSIPVSS---RKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARKVEG 551
            + P SS   RK WH  VTQDLRNHLVHKLVQAIFPTPD A L+D RM+NLVAYARKVEG
Sbjct: 568 TAAPPSSTGVRKAWHEHVTQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG 627

Query: 552 DMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQNAPNAQVPGMQGQIHPNA 607
           DMYESAN+R +YYH LAEKIYKIQKELEEKR  R++ Q   ++Q P       P A
Sbjct: 628 DMYESANSRDEYYHFLAEKIYKIQKELEEKRRSRLQKQGIMSSQAPLQAPGAQPTA 683
>gi|2996629|gb|AAC08447.1| CBP [Homo sapiens]
          Length = 555

 Score =  266 bits (680), Expect = 3e-69
 Identities = 186/372 (50%), Positives = 219/372 (58%), Gaps = 50/372 (13%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKGKSCEV 337
           +P+K KLIQQQLVLLLHAHKCQRREQ N E + C LP+CRTMKNVLNHMT C  GK+C+V
Sbjct: 81  DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQV 140

Query: 338 AHCASSRQIITHWKNCLRQDCPVCFALKIA-DKRNTQ-----------------GQSVNQ 379
           AHCASSRQII+HWKNC R DCPVC  LK A DKRN Q                 G     
Sbjct: 141 AHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQN 200

Query: 380 TSTMTAPNAADPATMKRAFESLGLQYNQNTPAHNAAQHGHPQMNAMQNDAGQINKTNMPN 439
            ++++ PN  DP++M+RA+ +LGL Y  N P     Q   P     Q    Q  +T  P 
Sbjct: 201 ATSLSNPNPIDPSSMQRAYAALGLPY-MNQP-QTQLQPQVPGQQPAQPQTHQQMRTLNPL 258

Query: 440 QQGPKVVPDQXXXXXXXXXXXXTGQLPQTIQPQSG--TQLXXXXXXXXXXXXXPDI--VK 495
              P  +P              T Q P  +  +S   T L              +I  + 
Sbjct: 259 GNNPMNIP---------AGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLS 309

Query: 496 SIPVSS-------RKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARK 548
           +IP ++       RK WH  VTQDLR+HLVHKLVQAIFPTPD A L+D RM+NLVAYA+K
Sbjct: 310 TIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKK 369

Query: 549 VEGDMYESANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQ----NAPNAQVPGMQGQIH 604
           VEGDMYESAN+R +YYHLLAEKIYKIQKELEEKR  R+  Q    N P    PG Q  + 
Sbjct: 370 VEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVI 429

Query: 605 PNAQ-----NGP 611
           P AQ     NGP
Sbjct: 430 PQAQPVRPPNGP 441
>gi|21105780|gb|AAM34788.1|AF512558_2 HAC5 [Arabidopsis thaliana]
          Length = 1012

 Score =  245 bits (626), Expect = 6e-63
 Identities = 144/375 (38%), Positives = 215/375 (57%), Gaps = 48/375 (12%)

Query: 1118 IPRDSMYYSY---QNRYVYCEKCFNEIQTDEVELSEDPTQPMTKIRKDQFDRVKNDQLDY 1174
            + R++M+Y+    ++R+  C  C+NE + + V +   P      + K +F++ KND+   
Sbjct: 426  VKRNAMHYTVVAGESRHYVCIPCYNEARANTVSVDGTP------VPKSRFEKKKNDEEVE 479

Query: 1175 EPFIDCQECGRRWHQICALWFESIWREG---WSCDSCLKAKGVKRKENKFTS-------K 1224
            E ++ C +C    HQICAL F      G   ++C +C   + V++ E K  S       K
Sbjct: 480  ESWVQCDKCQAWQHQICAL-FNGRRNHGQAEYTCPNCY-IQEVEQGERKPVSQNVILGAK 537

Query: 1225 KLPTTKLGTYLENRVNNFLRKKDS--------------GAGEVTIRVLSSYDKMTEVKPL 1270
             LP + L  +LE R+   L+++                GA  + IRV++S DK+ EVKP 
Sbjct: 538  SLPASTLSNHLEQRLFKKLKQERQERARLQGKSYEEVPGADSLVIRVVASVDKILEVKPR 597

Query: 1271 MKKRFGNDMEDS-YPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISYLD 1329
                F  D   S +PY++KA+  F++I+GV+VC FGM+VQE+G+    PN RRVY+SYLD
Sbjct: 598  FLDIFREDNYSSEFPYKSKAILLFQKIEGVEVCLFGMYVQEFGTDSASPNQRRVYLSYLD 657

Query: 1330 SVHFFKP-------RHLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHCHP 1382
            SV +F+P         LRT VYHEILIGYL+Y K  G+++ +IWACPP +G+DYI +CHP
Sbjct: 658  SVKYFRPDVRTVSGEALRTFVYHEILIGYLDYCKKRGFSSCYIWACPPLKGEDYILYCHP 717

Query: 1383 PEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKD-AIDSGISSAK----DLAYFEGD 1437
              QK PK  +L+EWY  ML KA  ++VVV+  + +    + SG   AK     L YF+GD
Sbjct: 718  EIQKTPKTDKLREWYLAMLKKASKEKVVVECTNFYDHFFVQSGECRAKVTAARLPYFDGD 777

Query: 1438 FWPNVIEESIKELDQ 1452
            +WP   E+ I ++ Q
Sbjct: 778  YWPGAAEDLIDQMSQ 792

 Score = 79.7 bits (195), Expect = 6e-13
 Identities = 43/117 (36%), Positives = 63/117 (53%), Gaps = 9/117 (7%)

Query: 1535 EKHKEVFFVIRLHNQQIAASLPP-ITEPDPAMSCELMDGRDAFLTTAREKHYEFSSLRRA 1593
            +K K V + + + N      +P  I + D  +  E  D R AFL+  +  HY++ +LRRA
Sbjct: 900  QKEKHVLYPVAIDN------IPTEIKDNDDILESEFFDTRQAFLSLCQGNHYQYDTLRRA 953

Query: 1594 KLSSMALLYELHNQGKDAFVYTCNSCKAAVETR--YHCSTCDDFDLCVPCYNKEGHH 1648
            K SSM +LY LHN    AF   C  C+  +ET   + C  C D+D+C  CY+K  +H
Sbjct: 954  KHSSMMILYHLHNPTVPAFAMACAICQQELETAQGWRCEVCPDYDVCNACYSKGINH 1010

 Score = 62.8 bits (151), Expect = 7e-08
 Identities = 38/123 (30%), Positives = 60/123 (48%), Gaps = 10/123 (8%)

Query: 290 LVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAHCASSRQIITH 349
           L+ LLH  KC   E N     C+  YC T K +L H+  C K  +C   +C  +RQ+I H
Sbjct: 94  LLFLLHVRKCNAAEDN-----CESKYCFTAKTLLKHINCC-KAPACAYQYCHQTRQLIHH 147

Query: 350 WKNCLRQDCPVC-FALKIADKRNTQGQSVNQTSTMTAPNAADPATMKRAFESLGLQYNQN 408
           +K+C  + CPVC F     +K+  +   + +    +A     P   K +FES+     ++
Sbjct: 148 YKHCGDEACPVCVFVKNFKEKQKEKFTFLQRAEPSSASLNHGP---KESFESMRTSSERD 204

Query: 409 TPA 411
           + A
Sbjct: 205 SEA 207
>gi|15230656|ref|NP_187904.1| CREB-binding protein -related [Arabidopsis thaliana]
 gi|15795129|dbj|BAB02507.1| CREB-binding protein-like [Arabidopsis thaliana]
          Length = 1670

 Score =  239 bits (609), Expect = 6e-61
 Identities = 144/375 (38%), Positives = 215/375 (57%), Gaps = 48/375 (12%)

Query: 1118 IPRDSMYYSY---QNRYVYCEKCFNEIQTDEVELSEDPTQPMTKIRKDQFDRVKNDQLDY 1174
            + R++M+Y+    ++R+  C  C+NE + + V +   P      + K +F++ KND+   
Sbjct: 954  VKRNAMHYTVVAGESRHYVCIPCYNEARANTVSVDGTP------VPKSRFEKKKNDEEVE 1007

Query: 1175 EPFIDCQECGRRWHQICALWFESIWREG---WSCDSCLKAKGVKRKENKFTS-------K 1224
            E ++ C +C    HQICAL F      G   ++C +C   + V++ E K  S       K
Sbjct: 1008 ESWVQCDKCQAWQHQICAL-FNGRRNHGQAEYTCPNCY-IQEVEQGERKPVSQNVILGAK 1065

Query: 1225 KLPTTKLGTYLENRVNNFLRKKDS--------------GAGEVTIRVLSSYDKMTEVKPL 1270
             LP + L  +LE R+   L+++                GA  + IRV++S DK+ EVKP 
Sbjct: 1066 SLPASTLSNHLEQRLFKKLKQERQERARLQGKSYEEVPGADSLVIRVVASVDKILEVKPR 1125

Query: 1271 MKKRFGNDMEDS-YPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISYLD 1329
                F  D   S +PY++KA+  F++I+GV+VC FGM+VQE+G+    PN RRVY+SYLD
Sbjct: 1126 FLDIFREDNYSSEFPYKSKAILLFQKIEGVEVCLFGMYVQEFGTDSASPNQRRVYLSYLD 1185

Query: 1330 SVHFFKP-------RHLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHCHP 1382
            SV +F+P         LRT VYHEILIGYL+Y K  G+++ +IWACPP +G+DYI +CHP
Sbjct: 1186 SVKYFRPDVRTVSGEALRTFVYHEILIGYLDYCKKRGFSSCYIWACPPLKGEDYILYCHP 1245

Query: 1383 PEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKD-AIDSGISSAK----DLAYFEGD 1437
              QK PK  +L+EWY  ML KA  ++VVV+  + +    + SG   AK     L YF+GD
Sbjct: 1246 EIQKTPKTDKLREWYLAMLKKASKEKVVVECTNFYDHFFVQSGECRAKVTAARLPYFDGD 1305

Query: 1438 FWPNVIEESIKELDQ 1452
            +WP   E+ I ++ Q
Sbjct: 1306 YWPGAAEDLIDQMSQ 1320

 Score =  113 bits (282), Expect = 4e-23
 Identities = 66/219 (30%), Positives = 110/219 (50%), Gaps = 19/219 (8%)

Query: 1535 EKHKEVFFVIRLHNQQIAASLPP-ITEPDPAMSCELMDGRDAFLTTAREKHYEFSSLRRA 1593
            +K K V + + + N      +P  I + D  +  E  D R AFL+  +  HY++ +LRRA
Sbjct: 1428 QKEKHVLYPVAIDN------IPTEIKDNDDILESEFFDTRQAFLSLCQGNHYQYDTLRRA 1481

Query: 1594 KLSSMALLYELHNQGKDAFVYTCNSCKAAVETR--YHCSTCDDFDLCVPCYNKE-GHHHK 1650
            K SSM +LY LHN    AF   C  C+  +ET   + C  C D+D+C  CY+K   H H 
Sbjct: 1482 KHSSMMILYHLHNPTVPAFAMACAICQQELETAQGWRCEVCPDYDVCNACYSKGINHPHS 1541

Query: 1651 MTKLGLGLDDIASSDKEENPQESRRKSIQRCISSLVHACQCRNANCRMNACHKMKRVVGH 1710
            +       D +  + +    Q ++ + +      L+H   C  A C+   C  +K ++ H
Sbjct: 1542 IISRPSATDSVVQNTQTNQIQNAQLREV------LLHVMTCCTAQCQYPRCRVIKGLIRH 1595

Query: 1711 TMSCRRKTNNGCPICKQLIALCCYHAKHCVENKCQVPFC 1749
             + C+ +   GC  CK++ +L   H+++C + +C+VP C
Sbjct: 1596 GLVCKTR---GCIACKKMWSLFRLHSRNCRDPQCKVPKC 1631

 Score = 61.2 bits (147), Expect = 2e-07
 Identities = 38/123 (30%), Positives = 60/123 (48%), Gaps = 10/123 (8%)

Query: 290 LVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAHCASSRQIITH 349
           L+ LLH  KC   E N     C+  YC T K +L H+  C K  +C   +C  +RQ+I H
Sbjct: 622 LLFLLHVRKCNAAEDN-----CESKYCFTAKTLLKHINCC-KAPACAYQYCHQTRQLIHH 675

Query: 350 WKNCLRQDCPVC-FALKIADKRNTQGQSVNQTSTMTAPNAADPATMKRAFESLGLQYNQN 408
           +K+C  + CPVC F     +K+  +   + +    +A     P   K +FES+     ++
Sbjct: 676 YKHCGDEACPVCVFVKNFKEKQKEKFTFLQRAEPSSASLNHGP---KESFESMRTSSERD 732

Query: 409 TPA 411
           + A
Sbjct: 733 SEA 735
>gi|27667568|ref|XP_213219.1| similar to CREB-binding protein [Mus musculus] [Rattus norvegicus]
          Length = 132

 Score =  238 bits (607), Expect = 1e-60
 Identities = 106/131 (80%), Positives = 117/131 (89%)

Query: 992  MPTLEKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPMDLSTIRRKLDSGLYSDPWEYV 1051
            MPTLE L++QDPESLPFRQPVDP +L IPDYFDIVK PMDLSTI+RKLD+G Y +PW+YV
Sbjct: 1    MPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYV 60

Query: 1052 DDVCLMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVMQSLGYCCGHKYVFCPQVLCCY 1111
            DDV LMF+NAWLYNRKTSRVYK+ SKL+EVFE EID VMQSLGYCCG KY F PQ LCCY
Sbjct: 61   DDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCY 120

Query: 1112 GKQLCTIPRDS 1122
            GKQLCTIPRD+
Sbjct: 121  GKQLCTIPRDA 131
>gi|7487910|pir||T01055 hypothetical protein YUP8H12R.38 - Arabidopsis thaliana
 gi|3152587|gb|AAC17068.1| Similar to CREB-binding protein homolog gb|U88570 from D.
            melanogaster and contains similarity to callus-associated
            protein gb|U01961 from Nicotiana tabacum.  EST gb|W43427
            comes from this gene. [Arabidopsis thaliana]
          Length = 1516

 Score =  236 bits (601), Expect = 5e-60
 Identities = 152/400 (38%), Positives = 217/400 (54%), Gaps = 54/400 (13%)

Query: 1096 CCGHKYVFCPQVLCCYGKQLCTIPRDSMYYSY---QNRYVYCEKCFNEIQTDEVELSEDP 1152
            C   K  F P  + C       I R++MYY+      R+ +C  C+NE + D + L+E  
Sbjct: 832  CAVEKLTFEPPPIYCTPCG-ARIKRNAMYYTVGAGDTRHYFCIPCYNESRGDTI-LAEGT 889

Query: 1153 TQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREG----WSCDSC 1208
              P  ++ K      KND+   E ++ C +C    HQICAL F     +G    ++C  C
Sbjct: 890  PMPKARLEKK-----KNDEETEEWWVQCDKCEAWQHQICAL-FNGRRNDGGQAEYTCPYC 943

Query: 1209 LKAKGVKRKENKFT------SKKLPTTKLGTYLENRVNNFLRKKDS-------------- 1248
              A+  + K           +K LP T L  ++E R+   L+++ +              
Sbjct: 944  FIAEVEQSKRKPLPQSAVLGAKDLPRTILSDHIEQRLFKRLKQERTERARAQGKSYDEIP 1003

Query: 1249 GAGEVTIRVLSSYDKMTEVKPLMKKRFGNDMEDSYP----YRAKAMFAFEEIDGVDVCFF 1304
             A  + IRV+SS DK  EVKP   + F    EDSYP    Y++K +  F++I+GV+VC F
Sbjct: 1004 TAESLVIRVVSSVDKKLEVKPRFLEIF---REDSYPTEFAYKSKVVLLFQKIEGVEVCLF 1060

Query: 1305 GMHVQEYGSSCPGPNTRRVYISYLDSVHFFKP-------RHLRTAVYHEILIGYLEYAKT 1357
            GM+VQE+GS C  PN RRVY+SYLDSV +F+P         LRT VYHEILIGYLEY K 
Sbjct: 1061 GMYVQEFGSECAFPNQRRVYLSYLDSVKYFRPEVRSYNGEALRTFVYHEILIGYLEYCKL 1120

Query: 1358 LGYTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIF 1417
             G+T+ +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  + +V +  +++
Sbjct: 1121 RGFTSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLAMLRKASKEGIVAETINLY 1180

Query: 1418 KD-AIDSGISSAK----DLAYFEGDFWPNVIEESIKELDQ 1452
                + +G   AK     L YF+GD+WP   E+ I ++ Q
Sbjct: 1181 DHFFMQTGECRAKVTAARLPYFDGDYWPGAAEDLIYQMSQ 1220

 Score =  142 bits (358), Expect = 7e-32
 Identities = 74/195 (37%), Positives = 116/195 (59%), Gaps = 8/195 (4%)

Query: 1560 EPDPAMSCELMDGRDAFLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCNSC 1619
            + D  +  E  D R AFL+  +  HY++ +LRRAK SSM +LY LHN    AFV TCN+C
Sbjct: 1324 DKDEILESEFFDTRQAFLSLCQGNHYQYDTLRRAKHSSMMVLYHLHNPTAPAFVTTCNAC 1383

Query: 1620 KAAVET--RYHCSTCDDFDLCVPCYNKEG---HHHKMTKLGLGLDDIASSDKEENPQESR 1674
               +ET   + C  C D+D+C  C++++G   H HK+T     L D  + +KE   ++ R
Sbjct: 1384 HLDIETGQGWRCEVCPDYDVCNACFSRDGGVNHPHKLTN-HPSLADQNAQNKE--ARQLR 1440

Query: 1675 RKSIQRCISSLVHACQCRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCCY 1734
               +++ +  LVHA QCR+A+C+   C K+K +  H ++C+ + + GC +CK++  L   
Sbjct: 1441 VLQLRKMLDLLVHASQCRSAHCQYPNCRKVKGLFRHGINCKVRASGGCVLCKKMWYLLQL 1500

Query: 1735 HAKHCVENKCQVPFC 1749
            HA+ C E++C VP C
Sbjct: 1501 HARACKESECHVPRC 1515

 Score = 45.8 bits (107), Expect = 0.009
 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 6/98 (6%)

Query: 287 QQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAHCASSRQI 346
           Q+ L+ L HA  C+       E +C    C T++ +  HM +C     C    C  ++ +
Sbjct: 518 QKWLLFLRHARHCKAP-----EGKCPDRNCVTVQKLWKHMDSC-AAPQCSYPRCLPTKTL 571

Query: 347 ITHWKNCLRQDCPVCFALKIADKRNTQGQSVNQTSTMT 384
           I H ++C   +CPVC  +K   ++    +S+ +    T
Sbjct: 572 INHHRSCKEPNCPVCIPVKAYLQQQANARSLARLKNET 609
>gi|18412221|ref|NP_565197.1| p300/CBP acetyltransferase-related protein 2 [Arabidopsis thaliana]
 gi|12597461|gb|AAG60059.1| p300/CBP acetyltransferase-related protein 2 [Arabidopsis thaliana]
          Length = 1654

 Score =  233 bits (595), Expect = 2e-59
 Identities = 152/400 (38%), Positives = 217/400 (54%), Gaps = 54/400 (13%)

Query: 1096 CCGHKYVFCPQVLCCYGKQLCTIPRDSMYYSY---QNRYVYCEKCFNEIQTDEVELSEDP 1152
            C   K  F P  + C       I R++MYY+      R+ +C  C+NE + D + L+E  
Sbjct: 946  CAVEKLTFEPPPIYCTPCG-ARIKRNAMYYTVGAGDTRHYFCIPCYNESRGDTI-LAEGT 1003

Query: 1153 TQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREG----WSCDSC 1208
              P  ++ K      KND+   E ++ C +C    HQICAL F     +G    ++C  C
Sbjct: 1004 PMPKARLEKK-----KNDEETEEWWVQCDKCEAWQHQICAL-FNGRRNDGGQAEYTCPYC 1057

Query: 1209 LKAKGVKRKENKFT------SKKLPTTKLGTYLENRVNNFLRKKDS-------------- 1248
              A+  + K           +K LP T L  ++E R+   L+++ +              
Sbjct: 1058 FIAEVEQSKRKPLPQSAVLGAKDLPRTILSDHIEQRLFKRLKQERTERARAQGKSYDEIP 1117

Query: 1249 GAGEVTIRVLSSYDKMTEVKPLMKKRFGNDMEDSYP----YRAKAMFAFEEIDGVDVCFF 1304
             A  + IRV+SS DK  EVKP   + F    EDSYP    Y++K +  F++I+GV+VC F
Sbjct: 1118 TAESLVIRVVSSVDKKLEVKPRFLEIF---REDSYPTEFAYKSKVVLLFQKIEGVEVCLF 1174

Query: 1305 GMHVQEYGSSCPGPNTRRVYISYLDSVHFFKP-------RHLRTAVYHEILIGYLEYAKT 1357
            GM+VQE+GS C  PN RRVY+SYLDSV +F+P         LRT VYHEILIGYLEY K 
Sbjct: 1175 GMYVQEFGSECAFPNQRRVYLSYLDSVKYFRPEVRSYNGEALRTFVYHEILIGYLEYCKL 1234

Query: 1358 LGYTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIF 1417
             G+T+ +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  + +V +  +++
Sbjct: 1235 RGFTSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLAMLRKASKEGIVAETINLY 1294

Query: 1418 KD-AIDSGISSAK----DLAYFEGDFWPNVIEESIKELDQ 1452
                + +G   AK     L YF+GD+WP   E+ I ++ Q
Sbjct: 1295 DHFFMQTGECRAKVTAARLPYFDGDYWPGAAEDLIYQMSQ 1334

 Score =  141 bits (355), Expect = 2e-31
 Identities = 74/195 (37%), Positives = 116/195 (59%), Gaps = 8/195 (4%)

Query: 1560 EPDPAMSCELMDGRDAFLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCNSC 1619
            + D  +  E  D R AFL+  +  HY++ +LRRAK SSM +LY LHN    AFV TCN+C
Sbjct: 1462 DKDEILESEFFDTRQAFLSLCQGNHYQYDTLRRAKHSSMMVLYHLHNPTAPAFVTTCNAC 1521

Query: 1620 KAAVET--RYHCSTCDDFDLCVPCYNKEG---HHHKMTKLGLGLDDIASSDKEENPQESR 1674
               +ET   + C  C D+D+C  C++++G   H HK+T     L D  + +KE   ++ R
Sbjct: 1522 HLDIETGQGWRCEVCPDYDVCNACFSRDGGVNHPHKLTN-HPSLADQNAQNKE--ARQLR 1578

Query: 1675 RKSIQRCISSLVHACQCRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCCY 1734
               +++ +  LVHA QCR+A+C+   C K+K +  H ++C+ + + GC +CK++  L   
Sbjct: 1579 VLQLRKMLDLLVHASQCRSAHCQYPNCRKVKGLFRHGINCKVRASGGCVLCKKMWYLLQL 1638

Query: 1735 HAKHCVENKCQVPFC 1749
            HA+ C E++C VP C
Sbjct: 1639 HARACKESECHVPRC 1653

 Score = 45.4 bits (106), Expect = 0.012
 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 6/98 (6%)

Query: 287 QQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAHCASSRQI 346
           Q+ L+ L HA  C+       E +C    C T++ +  HM +C     C    C  ++ +
Sbjct: 632 QKWLLFLRHARHCKAP-----EGKCPDRNCVTVQKLWKHMDSC-AAPQCSYPRCLPTKTL 685

Query: 347 ITHWKNCLRQDCPVCFALKIADKRNTQGQSVNQTSTMT 384
           I H ++C   +CPVC  +K   ++    +S+ +    T
Sbjct: 686 INHHRSCKEPNCPVCIPVKAYLQQQANARSLARLKNET 723
>gi|25518555|pir||E86302 hypothetical protein F17F16.8 [imported] - Arabidopsis thaliana
 gi|9954734|gb|AAG09087.1|AC026237_8 Unknown Protein [Arabidopsis thaliana]
          Length = 1498

 Score =  224 bits (570), Expect = 2e-56
 Identities = 149/398 (37%), Positives = 216/398 (54%), Gaps = 50/398 (12%)

Query: 1096 CCGHKYVFCPQVLCCYGKQLCTIPRDSMYYSY---QNRYVYCEKCFNEIQTDEVELSEDP 1152
            C   K  F P  + C       I R++MYY+    + R+ +C  C+NE + D + L+E  
Sbjct: 753  CAVEKLTFEPPPIYCTPCG-ARIKRNAMYYTVGGGETRHYFCIPCYNESRGDTI-LAEGT 810

Query: 1153 TQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREG----WSCDSC 1208
            + P  K+ K      KND+   E ++ C +C    HQICAL F     +G    ++C  C
Sbjct: 811  SMPKAKLEKK-----KNDEEIEESWVQCDKCQAWQHQICAL-FNGRRNDGGQAEYTCPYC 864

Query: 1209 LKAKGVKRKENK-------FTSKKLPTTKLGTYLENRVNNFLRKKDSGAGEVT------- 1254
                 V++ E K         +K LP T L  ++E R+   L+++ +    V        
Sbjct: 865  Y-VIDVEQNERKPLLQSAVLGAKDLPRTILSDHIEQRLFKRLKQERTERARVQGTSYDEI 923

Query: 1255 -------IRVLSSYDKMTEVKPLMKKRFGND-MEDSYPYRAKAMFAFEEIDGVDVCFFGM 1306
                   +RV+SS DK  EVK    + F  D     +PY++K +  F++I+GV+VC FGM
Sbjct: 924  PTVESLVVRVVSSVDKKLEVKSRFLEIFREDNFPTEFPYKSKVVLLFQKIEGVEVCLFGM 983

Query: 1307 HVQEYGSSCPGPNTRRVYISYLDSVHFFKP-------RHLRTAVYHEILIGYLEYAKTLG 1359
            +VQE+GS C  PN RRVY+SYLDSV +F+P         LRT VYHEILIGYLEY K  G
Sbjct: 984  YVQEFGSECSNPNQRRVYLSYLDSVKYFRPDIKSANGEALRTFVYHEILIGYLEYCKLRG 1043

Query: 1360 YTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKD 1419
            +T+ +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  + +V +  +++  
Sbjct: 1044 FTSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLAMLRKAAKEGIVAETTNLYDH 1103

Query: 1420 -AIDSGISSAK----DLAYFEGDFWPNVIEESIKELDQ 1452
              + +G   AK     L YF+GD+WP   E+ I ++ Q
Sbjct: 1104 FFLQTGECRAKVTAARLPYFDGDYWPGAAEDIISQMSQ 1141

 Score =  140 bits (352), Expect = 3e-31
 Identities = 85/232 (36%), Positives = 122/232 (52%), Gaps = 15/232 (6%)

Query: 1553 ASLPPIT-EPDPAMSCELMDGRDAFLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDA 1611
            A +P  T + D  +  E  D R AFL+  +  HY++ +LRRAK SSM +LY LHN    A
Sbjct: 1261 ADIPTDTKDRDEILESEFFDTRQAFLSLCQGNHYQYDTLRRAKHSSMMVLYHLHNPTAPA 1320

Query: 1612 FVYTCNSCKAAVET--RYHCSTCDDFDLCVPCYNKEG---HHHKMTKLGLGLDDIASSDK 1666
            FV TCN C   +E+   + C  C D+D+C  CY KEG   H HK+T     L D  + +K
Sbjct: 1321 FVTTCNVCHLDIESGLGWRCEVCPDYDVCNACYKKEGCINHPHKLTT-HPSLADQNAQNK 1379

Query: 1667 EENPQESRRKSIQRCISSLVHACQCRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPICK 1726
            E   ++ R   +++ +  LVHA QCR+  C    C K+K +  H + C+ + + GC +CK
Sbjct: 1380 E--ARQLRVLQLRKMLDLLVHASQCRSPVCLYPNCRKVKGLFRHGLRCKVRASGGCVLCK 1437

Query: 1727 QLIALCCYHAKHCVENKCQVPFCAXXXXXXXXXXXXTTLHQAQMLRRRVAIM 1778
            ++  L   HA+ C E++C VP C               L Q    RRR A+M
Sbjct: 1438 KMWYLLQLHARACKESECDVPRCGDLKEHLRR------LQQQSDSRRRAAVM 1483

 Score = 43.1 bits (100), Expect = 0.067
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 282 KSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAHCA 341
           K K  Q+ L+ L HA  C+          C+   C T++ + +HM  C   + C    C 
Sbjct: 432 KFKNQQRWLLFLRHARSCKPP-----GGRCQDQNCVTVQKLWSHMDNCADPQ-CLYPRCR 485

Query: 342 SSRQIITHWKNCLRQDCPVCFALK 365
            ++ +I H+KNC    CPVC  +K
Sbjct: 486 HTKALIGHYKNCKDPRCPVCVPVK 509
>gi|15219327|ref|NP_173115.1| expressed protein [Arabidopsis thaliana]
          Length = 1706

 Score =  223 bits (568), Expect = 3e-56
 Identities = 149/398 (37%), Positives = 216/398 (54%), Gaps = 50/398 (12%)

Query: 1096 CCGHKYVFCPQVLCCYGKQLCTIPRDSMYYSY---QNRYVYCEKCFNEIQTDEVELSEDP 1152
            C   K  F P  + C       I R++MYY+    + R+ +C  C+NE + D + L+E  
Sbjct: 961  CAVEKLTFEPPPIYCTPCG-ARIKRNAMYYTVGGGETRHYFCIPCYNESRGDTI-LAEGT 1018

Query: 1153 TQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREG----WSCDSC 1208
            + P  K+ K      KND+   E ++ C +C    HQICAL F     +G    ++C  C
Sbjct: 1019 SMPKAKLEKK-----KNDEEIEESWVQCDKCQAWQHQICAL-FNGRRNDGGQAEYTCPYC 1072

Query: 1209 LKAKGVKRKENK-------FTSKKLPTTKLGTYLENRVNNFLRKKDSGAGEVT------- 1254
                 V++ E K         +K LP T L  ++E R+   L+++ +    V        
Sbjct: 1073 Y-VIDVEQNERKPLLQSAVLGAKDLPRTILSDHIEQRLFKRLKQERTERARVQGTSYDEI 1131

Query: 1255 -------IRVLSSYDKMTEVKPLMKKRFGND-MEDSYPYRAKAMFAFEEIDGVDVCFFGM 1306
                   +RV+SS DK  EVK    + F  D     +PY++K +  F++I+GV+VC FGM
Sbjct: 1132 PTVESLVVRVVSSVDKKLEVKSRFLEIFREDNFPTEFPYKSKVVLLFQKIEGVEVCLFGM 1191

Query: 1307 HVQEYGSSCPGPNTRRVYISYLDSVHFFKP-------RHLRTAVYHEILIGYLEYAKTLG 1359
            +VQE+GS C  PN RRVY+SYLDSV +F+P         LRT VYHEILIGYLEY K  G
Sbjct: 1192 YVQEFGSECSNPNQRRVYLSYLDSVKYFRPDIKSANGEALRTFVYHEILIGYLEYCKLRG 1251

Query: 1360 YTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKD 1419
            +T+ +IWACPP +G+DYI +CHP  QK PK  +L+EWY  ML KA  + +V +  +++  
Sbjct: 1252 FTSCYIWACPPLKGEDYILYCHPEIQKTPKSDKLREWYLAMLRKAAKEGIVAETTNLYDH 1311

Query: 1420 -AIDSGISSAK----DLAYFEGDFWPNVIEESIKELDQ 1452
              + +G   AK     L YF+GD+WP   E+ I ++ Q
Sbjct: 1312 FFLQTGECRAKVTAARLPYFDGDYWPGAAEDIISQMSQ 1349

 Score =  139 bits (351), Expect = 5e-31
 Identities = 85/232 (36%), Positives = 122/232 (52%), Gaps = 15/232 (6%)

Query: 1553 ASLPPIT-EPDPAMSCELMDGRDAFLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDA 1611
            A +P  T + D  +  E  D R AFL+  +  HY++ +LRRAK SSM +LY LHN    A
Sbjct: 1469 ADIPTDTKDRDEILESEFFDTRQAFLSLCQGNHYQYDTLRRAKHSSMMVLYHLHNPTAPA 1528

Query: 1612 FVYTCNSCKAAVET--RYHCSTCDDFDLCVPCYNKEG---HHHKMTKLGLGLDDIASSDK 1666
            FV TCN C   +E+   + C  C D+D+C  CY KEG   H HK+T     L D  + +K
Sbjct: 1529 FVTTCNVCHLDIESGLGWRCEVCPDYDVCNACYKKEGCINHPHKLTT-HPSLADQNAQNK 1587

Query: 1667 EENPQESRRKSIQRCISSLVHACQCRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPICK 1726
            E   ++ R   +++ +  LVHA QCR+  C    C K+K +  H + C+ + + GC +CK
Sbjct: 1588 E--ARQLRVLQLRKMLDLLVHASQCRSPVCLYPNCRKVKGLFRHGLRCKVRASGGCVLCK 1645

Query: 1727 QLIALCCYHAKHCVENKCQVPFCAXXXXXXXXXXXXTTLHQAQMLRRRVAIM 1778
            ++  L   HA+ C E++C VP C               L Q    RRR A+M
Sbjct: 1646 KMWYLLQLHARACKESECDVPRCGDLKEHLRR------LQQQSDSRRRAAVM 1691

 Score = 42.7 bits (99), Expect = 0.074
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 282 KSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAHCA 341
           K K  Q+ L+ L HA  C+          C+   C T++ + +HM  C   + C    C 
Sbjct: 640 KFKNQQRWLLFLRHARSCKPP-----GGRCQDQNCVTVQKLWSHMDNCADPQ-CLYPRCR 693

Query: 342 SSRQIITHWKNCLRQDCPVCFALK 365
            ++ +I H+KNC    CPVC  +K
Sbjct: 694 HTKALIGHYKNCKDPRCPVCVPVK 717
>gi|18405622|ref|NP_564706.1| CREB-binding protein -related [Arabidopsis thaliana]
          Length = 1456

 Score =  204 bits (518), Expect = 2e-50
 Identities = 137/396 (34%), Positives = 210/396 (53%), Gaps = 48/396 (12%)

Query: 1090 MQSLGYCCGHKYVFCPQVLCCYGKQLCTIPRDSMYYSY---QNRYVYCEKCFNEIQTDEV 1146
            + S   C     VF P  + C    +  I +++++YS    ++R+  C  C+NE +   V
Sbjct: 721  VNSCQLCAVEWLVFEPVPIYCSPCGI-RIKKNALHYSIAVGESRHYVCAPCYNEAREKLV 779

Query: 1147 ELSEDPTQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREG---- 1202
             L        T I K +  + KND+   E ++ C +C    H ICAL F S    G    
Sbjct: 780  FLDG------TSIPKTRLQKKKNDEQVPEGWVQCDKCEAWQHIICAL-FNSRRNHGESTK 832

Query: 1203 WSCDSCLKAKGVKRKENKFT------SKKLPTTKLGTYLENRVNNFLRKKDS-------- 1248
            ++C SC   +  +R+           +  LP T L  +LE R+   L+++          
Sbjct: 833  YTCPSCYIQEVEQRERRPLPLSAVPGATSLPVTSLSKHLEERLFKKLKEERQERARLQGK 892

Query: 1249 ------GAGEVTIRVLSSYDKMTEVKPLMKKRFGNDMEDS-YPYRAKAMFAFEEIDGVDV 1301
                  GA  +T+RV++S DK+ EVK    + F  +   S +PY++KA+F F++I+ V+V
Sbjct: 893  TYEEVPGAESLTVRVVASVDKVLEVKERFLELFREENYPSEFPYKSKAIFLFQKIENVEV 952

Query: 1302 CFFGMHVQEYGSSCPGPNTRRVYISYLDSVHFFKPRHLRTAVYHEILIGYLEYAKTLGYT 1361
            C FGM VQE+G+    PN RR + +            LRT VYHEILIGYL+Y K  G+T
Sbjct: 953  CLFGMFVQEFGTDSGPPNERRTFRT-------VSGEALRTFVYHEILIGYLDYCKKRGFT 1005

Query: 1362 TAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFKD-A 1420
            + +IWACPP +GDDYI +CHP  QK PK  +L+EWY  ML KA  + VVV+  +++    
Sbjct: 1006 SCYIWACPPLKGDDYILYCHPEIQKTPKTDKLREWYLAMLRKASKEDVVVECTNLYNHFF 1065

Query: 1421 IDSGIS----SAKDLAYFEGDFWPNVIEESIKELDQ 1452
            + SG      +A  L YF+GD+WP+  E+ +++++Q
Sbjct: 1066 VQSGECRANVTAARLPYFDGDYWPSAAEDLLRQMNQ 1101

 Score =  122 bits (305), Expect = 1e-25
 Identities = 76/225 (33%), Positives = 109/225 (48%), Gaps = 14/225 (6%)

Query: 1558 ITEPDPAMSCELMDGRDAFLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCN 1617
            I + D  +  E    R AFL   +  +Y++ +LRRAK SSM +LY LHN    AF   C 
Sbjct: 1228 IEDKDNNLESEFFHNRQAFLNLCQGNNYQYETLRRAKHSSMMILYHLHNPTAPAFATVCT 1287

Query: 1618 SCKAAVETR--YHCSTCDDFDLCVPCYNKEGHHHKMTKLGLGLDDIASSDKEENPQESRR 1675
             C+  VE    +HC  C  +D+C  CY+K+  +H   KL        S+  ++N Q S+ 
Sbjct: 1288 ICQQEVENSQGWHCEVCPGYDVCSACYSKDSINHSH-KLTSRSSSTDSTVVQQNGQASQS 1346

Query: 1676 KSI--QRCISSLVHACQCRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCC 1733
              +  ++    LVHA  CR+  C+   C K K +  H + C   T   CPICK L +L  
Sbjct: 1347 YQVKLEKLKKLLVHAATCRSTQCQYQGCRKSKMLFRHCIDC---TTGDCPICKGLWSLLK 1403

Query: 1734 YHAKHCVENKCQVPFCAXXXXXXXXXXXXTTLHQAQMLRRRVAIM 1778
             HA++C ++KC VP C+                Q    RRR A+M
Sbjct: 1404 LHARNCRDSKCTVPKCSGLRAISRRK------QQQADKRRRAAVM 1442
>gi|5042442|gb|AAD38279.1|AC007789_5 putative CREB-binding protein [Oryza sativa (japonica
            cultivar-group)]
          Length = 994

 Score =  200 bits (509), Expect = 2e-49
 Identities = 112/317 (35%), Positives = 178/317 (56%), Gaps = 45/317 (14%)

Query: 1175 EPFIDCQECGRRWHQICALWFESIW--REGWSCDSCLKAKGVKRKENK----------FT 1222
            E ++ C +C    HQICAL+   I      ++C  C     +K K+N+            
Sbjct: 493  EWWVQCDKCKAWQHQICALFNPKIVDPEAEYTCAKCF----LKEKDNEDVDSLEPSTILG 548

Query: 1223 SKKLPTTKLGTYLENRVNNFLRKKDS--------------GAGEVTIRVLSSYDKMTEVK 1268
            +++LP T+L  ++E R++  L ++                G   +T+RV+SS D+  +V+
Sbjct: 549  ARELPRTRLSDHIEQRLSERLVQERQQRAIASGKSVDEVPGVEGLTVRVVSSADRTLQVQ 608

Query: 1269 PLMKKRFGNDM-EDSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISY 1327
            P  K  F  +     +PY++KA+  F++ +GVDVC F M+VQEYGS+CP PN R VY++Y
Sbjct: 609  PRFKDFFKKEQYPGEFPYKSKAILLFQKNEGVDVCLFAMYVQEYGSACPSPNQRHVYLAY 668

Query: 1328 LDSVHFFKP-------RHLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHC 1380
            +DSV +F+P         LRT VYHEILIGYL++ K  G+ +  IW CP ++ DDY+ +C
Sbjct: 669  IDSVKYFRPEIKSASGEALRTFVYHEILIGYLDFCKKRGFVSCSIWTCPSTKRDDYVLYC 728

Query: 1381 HPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIF------KDAIDSGISSAKDLAYF 1434
            HP  QK+PK  +L+ WY+ ++ KA+ + VVV+   ++       +   + IS+A  L Y 
Sbjct: 729  HPTIQKMPKSDKLRSWYQNLVKKAVKEGVVVERNTLYDFFLQPTNECKTNISAAW-LPYC 787

Query: 1435 EGDFWPNVIEESIKELD 1451
            + DFWP   E  +++ D
Sbjct: 788  DNDFWPGEAERLLEKKD 804
>gi|13486836|dbj|BAB40067.1| putative CREB-binding protein [Oryza sativa (japonica
            cultivar-group)]
          Length = 936

 Score =  200 bits (509), Expect = 3e-49
 Identities = 112/317 (35%), Positives = 178/317 (56%), Gaps = 45/317 (14%)

Query: 1175 EPFIDCQECGRRWHQICALWFESIW--REGWSCDSCLKAKGVKRKENK----------FT 1222
            E ++ C +C    HQICAL+   I      ++C  C     +K K+N+            
Sbjct: 435  EWWVQCDKCKAWQHQICALFNPKIVDPEAEYTCAKCF----LKEKDNEDVDSLEPSTILG 490

Query: 1223 SKKLPTTKLGTYLENRVNNFLRKKDS--------------GAGEVTIRVLSSYDKMTEVK 1268
            +++LP T+L  ++E R++  L ++                G   +T+RV+SS D+  +V+
Sbjct: 491  ARELPRTRLSDHIEQRLSERLVQERQQRAIASGKSVDEVPGVEGLTVRVVSSADRTLQVQ 550

Query: 1269 PLMKKRFGNDM-EDSYPYRAKAMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISY 1327
            P  K  F  +     +PY++KA+  F++ +GVDVC F M+VQEYGS+CP PN R VY++Y
Sbjct: 551  PRFKDFFKKEQYPGEFPYKSKAILLFQKNEGVDVCLFAMYVQEYGSACPSPNQRHVYLAY 610

Query: 1328 LDSVHFFKP-------RHLRTAVYHEILIGYLEYAKTLGYTTAHIWACPPSEGDDYIFHC 1380
            +DSV +F+P         LRT VYHEILIGYL++ K  G+ +  IW CP ++ DDY+ +C
Sbjct: 611  IDSVKYFRPEIKSASGEALRTFVYHEILIGYLDFCKKRGFVSCSIWTCPSTKRDDYVLYC 670

Query: 1381 HPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIF------KDAIDSGISSAKDLAYF 1434
            HP  QK+PK  +L+ WY+ ++ KA+ + VVV+   ++       +   + IS+A  L Y 
Sbjct: 671  HPTIQKMPKSDKLRSWYQNLVKKAVKEGVVVERNTLYDFFLQPTNECKTNISAAW-LPYC 729

Query: 1435 EGDFWPNVIEESIKELD 1451
            + DFWP   E  +++ D
Sbjct: 730  DNDFWPGEAERLLEKKD 746
>gi|23200188|pdb|1JSP|B Chain B, Nmr Structure Of Cbp Bromodomain In Complex With P53 Peptide
          Length = 121

 Score =  199 bits (507), Expect = 4e-49
 Identities = 92/116 (79%), Positives = 104/116 (89%)

Query: 979  KKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPMDLSTIRRK 1038
            KK+F  +ELRQALMPTLE L++QDPESLPFRQPVDP +L IPDYFDIVK PMDLSTI+RK
Sbjct: 6    KKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRK 65

Query: 1039 LDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVMQSLG 1094
            LD+G Y +PW+YVDDV LMF+NAWLYNRKTSRVYK+ SKL+EVFE EID VMQSLG
Sbjct: 66   LDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG 121
>gi|18408717|ref|NP_564891.1| hypothetical protein [Arabidopsis thaliana]
 gi|25404951|pir||B96696 protein F1N21.4 [imported] - Arabidopsis thaliana
 gi|9828615|gb|AAG00238.1|AC002130_3 F1N21.4 [Arabidopsis thaliana]
          Length = 1357

 Score =  199 bits (505), Expect = 7e-49
 Identities = 133/406 (32%), Positives = 198/406 (48%), Gaps = 56/406 (13%)

Query: 1091 QSLGYCCGHKYVFCPQVLCCYGKQLCT--IPRDSMYYS------YQNRYVYCEKCFNEIQ 1142
            +S   C     +F PQ L C    LC+  I   S YY+         ++  C  C +  +
Sbjct: 643  ESCQLCDDGTLLFPPQPLYCL---LCSRRIDDRSFYYTPGEEELSNAQHQICSPCHSRCK 699

Query: 1143 TDEVELSEDPTQPMTKIRKDQFDRVKN---DQLDYEPFIDCQECGRRWHQICALWFESIW 1199
            T           P+  +  D+   +K    D  D E ++ C+ C +  HQIC L+ +   
Sbjct: 700  T---------KFPLCGVFIDKHKMLKRSNFDNADTEEWVQCESCEKWQHQICGLYNKLKD 750

Query: 1200 REG---WSCDSCLKAKGVKRKENKFT------SKKLPTTKLGTYLENRVNNFLRKKDSGA 1250
             +    + C +CL  +                +K LP T L  +LE R+   L+++    
Sbjct: 751  EDKTAEYICPTCLLEECQSINNMALVDYTDSGAKDLPETVLSYFLEQRLFKRLKEERYQT 810

Query: 1251 GE--------------VTIRVLSSYDK-MTEVKPLMKKRFGNDMEDSYPYRAKAMFAFEE 1295
             +              +T+RV+ S D+ +T  K         +    +PYR+K +  F++
Sbjct: 811  AKATGKSINDVPEPEGLTLRVVFSADRTLTVNKQFASLLHKENFPSEFPYRSKVILLFQK 870

Query: 1296 IDGVDVCFFGMHVQEYGSSCPGPNTRRVYISYLDSVHFFKPRH-------LRTAVYHEIL 1348
            + GVD+C F + VQE+GS C  PN R  YI YLDSV +FKP         LRT VYHE+L
Sbjct: 871  VHGVDICIFALFVQEFGSECSQPNQRSTYIFYLDSVKYFKPERVTFAGEALRTFVYHEVL 930

Query: 1349 IGYLEYAKTLGYTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKMLDKAIIDR 1408
            IGYLEY K  G+TT++IWACPP  G DYI + HP  Q+ P  K+L++WY  ML KA   R
Sbjct: 931  IGYLEYCKLRGFTTSYIWACPPKIGQDYIMYSHPKTQQTPDTKKLRKWYVSMLQKAAEQR 990

Query: 1409 VVVDYKDIFKDAIDSG--ISSAKDLAYFEGDFWPNVIEESIKELDQ 1452
            VV++  +++    DS     +A  L YFEG FW N  E  I+++++
Sbjct: 991  VVMNVTNLYDRFFDSTEEYMTAARLPYFEGSFWSNRAEIMIQDIER 1036

 Score = 88.2 bits (217), Expect = 2e-15
 Identities = 67/235 (28%), Positives = 101/235 (42%), Gaps = 31/235 (13%)

Query: 1530 LYNHMEKHKEVFFVIRLHNQQIAASLPPITEP-DPAMSCELMDGRDAFLTTAREKHYEFS 1588
            +Y  M+K K      +L   Q+   L   TE  D     ++ + R AFL  +++ +Y F 
Sbjct: 1138 IYKRMDKEKH-----QLSKVQVNGVLFSTTEDNDIIQENDMFESRQAFLAFSQKHNYNFH 1192

Query: 1589 SLRRAKLSSMALLYELHNQGK-----DAFVYTCNSCKAAVETR--YHCSTCDDFDLCVPC 1641
            +LR AK SSM +L+ LH   K     ++   TC +CK  V T   + C  C D+  C  C
Sbjct: 1193 TLRHAKHSSMMILHHLHTSNKHHCSQNSSSLTCTACKKDVSTTIYFPCLLCPDYRACTGC 1252

Query: 1642 YNKE---GHHHKMTKLGLGLDDIASSDKEENPQESRRKSIQRCISSLVHACQCRN---AN 1695
            Y K     H H    L              N   SR   +   ++++ HA  C++    +
Sbjct: 1253 YTKNRTLRHLHIFPTL-----------PSANRAPSRTVMVLEILNAISHALLCQHKTTKS 1301

Query: 1696 CRMNACHKMKRVVGHTMSCR-RKTNNGCPICKQLIALCCYHAKHCVENKCQVPFC 1749
            C    CH++K +  H + C+ RK    C  C +L      H  HC +  C VP C
Sbjct: 1302 CSYPKCHEVKALFTHNVQCKIRKKGTRCNTCYKLWQTIRIHVYHCQDLNCPVPQC 1356
>gi|6056385|gb|AAF02849.1|AC009894_20 Unknown protein [Arabidopsis thaliana]
          Length = 1209

 Score =  177 bits (448), Expect = 2e-42
 Identities = 130/406 (32%), Positives = 199/406 (49%), Gaps = 77/406 (18%)

Query: 1090 MQSLGYCCGHKYVFCPQVLCCYGKQLCTIPRDSMYYSY---QNRYVYCEKCFNEIQTDEV 1146
            + S   C     VF P  + C    +  I +++++YS    ++R+  C  C+NE +   V
Sbjct: 721  VNSCQLCAVEWLVFEPVPIYCSPCGI-RIKKNALHYSIAVGESRHYVCAPCYNEAREKLV 779

Query: 1147 ELSEDPTQPMTKIRKDQFDRVKNDQLDYEPFIDCQECGRRWHQICALWFESIWREG---- 1202
             L        T I K +  + KND+   E ++ C +C    H ICAL F S    G    
Sbjct: 780  FLDG------TSIPKTRLQKKKNDEQVPEGWVQCDKCEAWQHIICAL-FNSRRNHGESTK 832

Query: 1203 WSCDSCLKAKGVKRKENKFT------SKKLPTTKLGTYLENR------------------ 1238
            ++C SC   +  +R+           +  LP T L  +LE R                  
Sbjct: 833  YTCPSCYIQEVEQRERRPLPLSAVPGATSLPVTSLSKHLEERLFKKLKEERQERARLQGK 892

Query: 1239 -----VNNFLRKKD-SGAGEVTIRVLSSYDKMTEVKPLMKKRFGNDMEDS-YPYRAKAMF 1291
                 ++N LR     GA  +T+RV++S DK+ EVK    + F  +   S +PY++KA+F
Sbjct: 893  TYEEVISNSLRLSTVPGAESLTVRVVASVDKVLEVKERFLELFREENYPSEFPYKSKAIF 952

Query: 1292 AFEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISYLDSVHFFKPRHLRTAVYHEILIGY 1351
             F++I+ V+VC FGM VQE+G+    PN RR                          IGY
Sbjct: 953  LFQKIENVEVCLFGMFVQEFGTDSGPPNERR--------------------------IGY 986

Query: 1352 LEYAKTLGYTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKMLDKAIIDRVVV 1411
            L+Y K  G+T+ +IWACPP +GDDYI +CHP  QK PK  +L+EWY  ML KA  + VVV
Sbjct: 987  LDYCKKRGFTSCYIWACPPLKGDDYILYCHPEIQKTPKTDKLREWYLAMLRKASKEDVVV 1046

Query: 1412 DYKDIFKD-AIDSGIS----SAKDLAYFEGDFWPNVIEESIKELDQ 1452
            +  +++    + SG      +A  L YF+GD+WP+  E+ +++++Q
Sbjct: 1047 ECTNLYNHFFVQSGECRANVTAARLPYFDGDYWPSAAEDLLRQMNQ 1092
>gi|8778322|gb|AAF79331.1|AC002304_24 F14J16.27 [Arabidopsis thaliana]
          Length = 1550

 Score =  168 bits (425), Expect = 1e-39
 Identities = 135/459 (29%), Positives = 212/459 (46%), Gaps = 106/459 (23%)

Query: 1090 MQSLGYCCGHKYVFCPQVLCCYGKQLCTIPRDSMYYSY---QNRYVYCEKCFNEIQTDEV 1146
            + S   C     VF P  + C    +  I +++++YS    ++R+  C  C+NE +   V
Sbjct: 721  VNSCQLCAVEWLVFEPVPIYCSPCGI-RIKKNALHYSIAVGESRHYVCAPCYNEAREKLV 779

Query: 1147 ELSEDPTQPMTKIRKDQFDR------------------------------VKNDQLDYEP 1176
             L +  + P T+++K + D                                 N    +  
Sbjct: 780  FL-DGTSIPKTRLQKKKNDEQVPEGVCMPHDFGNLFLPLFFFFFVFFFCVCLNQTNGFLQ 838

Query: 1177 FIDCQECGRRWHQICALWFESIWREG----WSCDSCLKAKGVKRKENKFT------SKKL 1226
            ++ C +C    H ICAL F S    G    ++C SC   +  +R+           +  L
Sbjct: 839  WVQCDKCEAWQHIICAL-FNSRRNHGESTKYTCPSCYIQEVEQRERRPLPLSAVPGATSL 897

Query: 1227 PTTKLGTYLENRVNNFLRKKDS--------------GAGEVTIRVLSSYDKMTEVKPLMK 1272
            P T L  +LE R+   L+++                GA  +T+RV++S DK+ EVK    
Sbjct: 898  PVTSLSKHLEERLFKKLKEERQERARLQGKTYEEVPGAESLTVRVVASVDKVLEVKERFL 957

Query: 1273 KRFGNDMEDS-YPYRAK---AMFAFEEIDGVDVCFFGMHVQEYGSSCPGPNTRRVYISYL 1328
            + F  +   S +PY++K   A+F F++I+ V+VC FGM VQE+G+    PN RR + +  
Sbjct: 958  ELFREENYPSEFPYKSKVAMAIFLFQKIENVEVCLFGMFVQEFGTDSGPPNERRTFRT-- 1015

Query: 1329 DSVHFFKPRHLRTAVYHEIL------------------------------IGYLEYAKTL 1358
                      LRT VYHEIL                              IGYL+Y K  
Sbjct: 1016 -----VSGEALRTFVYHEILVSRFISNPIFFRFRVLLHEYMKLIIVTNLQIGYLDYCKKR 1070

Query: 1359 GYTTAHIWACPPSEGDDYIFHCHPPEQKIPKPKRLQEWYKKMLDKAIIDRVVVDYKDIFK 1418
            G+T+ +IWACPP +GDDYI +CHP  QK PK  +L+EWY  ML KA  + VVV+  +++ 
Sbjct: 1071 GFTSCYIWACPPLKGDDYILYCHPEIQKTPKTDKLREWYLAMLRKASKEDVVVECTNLYN 1130

Query: 1419 D-AIDSGIS----SAKDLAYFEGDFWPNVIEESIKELDQ 1452
               + SG      +A  L YF+GD+WP+  E+ +++++Q
Sbjct: 1131 HFFVQSGECRANVTAARLPYFDGDYWPSAAEDLLRQMNQ 1169

 Score =  128 bits (322), Expect = 1e-27
 Identities = 89/282 (31%), Positives = 130/282 (46%), Gaps = 16/282 (5%)

Query: 1503 ANKSKGSARKNNRKTNLPQGTNDLTAKLYNHMEKHKEVFFVIRLHNQQIAASLPP--ITE 1560
            +N S      N+R   + Q   ++     N  EKH     + R  + Q+A    P  I +
Sbjct: 1265 SNHSTKQLSFNHRCYEVEQNRINIERHPINQKEKHALFPKLTRCGSLQVAIKDVPTKIED 1324

Query: 1561 PDPAMSCELMDGRDAFLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCNSCK 1620
             D  +  E    R AFL   +  +Y++ +LRRAK SSM +LY LHN    AF   C  C+
Sbjct: 1325 KDNNLESEFFHNRQAFLNLCQGNNYQYETLRRAKHSSMMILYHLHNPTAPAFATVCTICQ 1384

Query: 1621 AAVETR--YHCSTCDDFDLCVPCYNKEGHHHKMTKLGLGLDDIASSDKEENPQESRRKSI 1678
              VE    +HC  C  +D+C  CY+K+  +H   KL        S+  ++N Q S+   +
Sbjct: 1385 QEVENSQGWHCEVCPGYDVCSACYSKDSINHSH-KLTSRSSSTDSTVVQQNGQASQSYQV 1443

Query: 1679 --QRCISSLVHACQCRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCCYHA 1736
              ++    LVHA  CR+  C+   C K K +  H + C   T   CPICK L +L   HA
Sbjct: 1444 KLEKLKKLLVHAATCRSTQCQYQGCRKSKMLFRHCIDC---TTGDCPICKGLWSLLKLHA 1500

Query: 1737 KHCVENKCQVPFCAXXXXXXXXXXXXTTLHQAQMLRRRVAIM 1778
            ++C ++KC VP C+                Q    RRR A+M
Sbjct: 1501 RNCRDSKCTVPKCSGLRAISRRK------QQQADKRRRAAVM 1536

 Score = 39.3 bits (90), Expect = 0.95
 Identities = 19/89 (21%), Positives = 42/89 (47%), Gaps = 6/89 (6%)

Query: 283 SKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAHCAS 342
           S  + + +  + HA  C+ +     + +C   +C   + ++ H+  C K  +C+  +C  
Sbjct: 420 SNTVLRWIPFMFHARHCKAK-----KDKCASKFCFQARKIVKHIDCC-KVPNCKYRYCLG 473

Query: 343 SRQIITHWKNCLRQDCPVCFALKIADKRN 371
           +R  + H+K C    C  C A++   ++N
Sbjct: 474 TRMWLDHFKQCKSISCRTCVAVREYMEKN 502
>gi|11514507|pdb|1F81|A Chain A, Solution Structure Of The Taz2 Domain Of The Transcriptional
            Adaptor Protein Cbp
          Length = 88

 Score =  145 bits (367), Expect = 7e-33
 Identities = 65/81 (80%), Positives = 70/81 (86%)

Query: 1669 NPQESRRKSIQRCISSLVHACQCRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQL 1728
            +PQESRR SIQRCI SLVHACQCRNANC + +C KMKRVV HT  C+RKTN GCP+CKQL
Sbjct: 2    SPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQL 61

Query: 1729 IALCCYHAKHCVENKCQVPFC 1749
            IALCCYHAKHC ENKC VPFC
Sbjct: 62   IALCCYHAKHCQENKCPVPFC 82

 Score = 45.4 bits (106), Expect = 0.012
 Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 12/94 (12%)

Query: 280 PDKSKLIQQQLVLLLHAHKCQRREQNNIEQECKLPYCRTMKNVLNHMTTCNKGKSCEVAH 339
           P +S+ +  Q  +    H CQ R  N     C LP C+ MK V+ H   C +  +     
Sbjct: 3   PQESRRLSIQRCIQSLVHACQCRNAN-----CSLPSCQKMKRVVQHTKGCKRKTN---GG 54

Query: 340 CASSRQIIT----HWKNCLRQDCPVCFALKIADK 369
           C   +Q+I     H K+C    CPV F L I  K
Sbjct: 55  CPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHK 88
>gi|4139873|pdb|1KDX|A Chain A, Kix Domain Of Mouse Cbp (Creb Binding Protein) In Complex
           With Phosphorylated Kinase Inducible Domain (Pkid) Of
           Rat Creb (Cyclic Amp Response Element Binding Protein),
           Nmr 17 Structures
          Length = 81

 Score =  143 bits (361), Expect = 3e-32
 Identities = 66/79 (83%), Positives = 72/79 (91%)

Query: 502 RKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARKVEGDMYESANNRG 561
           RK WH  VTQDLR+HLVHKLVQAIFPTPD A L+D RM+NLVAYA+KVEGDMYESAN+R 
Sbjct: 3   RKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRD 62

Query: 562 QYYHLLAEKIYKIQKELEE 580
           +YYHLLAEKIYKIQKELEE
Sbjct: 63  EYYHLLAEKIYKIQKELEE 81
>gi|20664269|pdb|1L3E|B Chain B, Nmr Structures Of The Hif-1alpha CtadP300 CH1 COMPLEX
 gi|33357860|pdb|1P4Q|B Chain B, Solution Structure Of The Cited2 Transactivation Domain In
           Complex With The P300 Ch1 Domain
          Length = 101

 Score =  125 bits (314), Expect = 1e-26
 Identities = 70/90 (77%), Positives = 77/90 (85%), Gaps = 1/90 (1%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKGKSCEV 337
           +P+K KLIQQQLVLLLHAHKCQRREQ N E ++C LP+CRTMKNVLNHMT C  GKSC+V
Sbjct: 9   DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQV 68

Query: 338 AHCASSRQIITHWKNCLRQDCPVCFALKIA 367
           AHCASSRQII+HWKNC R DCPVC  LK A
Sbjct: 69  AHCASSRQIISHWKNCTRHDCPVCLPLKNA 98
>gi|20664319|pdb|1L8C|A Chain A, Structural Basis For Hif-1alphaCBP RECOGNITION IN THE
           Cellular Hypoxic Response
          Length = 95

 Score =  124 bits (312), Expect = 2e-26
 Identities = 72/94 (76%), Positives = 79/94 (84%), Gaps = 2/94 (2%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE-QECKLPYCRTMKNVLNHMTTCNKGKSCEV 337
           +P+K KLIQQQLVLLLHAHKCQRREQ N E + C LP+CRTMKNVLNHMT C  GK+C+V
Sbjct: 2   DPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQV 61

Query: 338 AHCASSRQIITHWKNCLRQDCPVCFALKIA-DKR 370
           AHCASSRQII+HWKNC R DCPVC  LK A DKR
Sbjct: 62  AHCASSRQIISHWKNCTRHDCPVCLPLKNASDKR 95
>gi|14794966|gb|AAK73519.1| HAC4 [Arabidopsis thaliana]
          Length = 413

 Score =  124 bits (310), Expect = 3e-26
 Identities = 76/225 (33%), Positives = 109/225 (48%), Gaps = 14/225 (6%)

Query: 1558 ITEPDPAMSCELMDGRDAFLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCN 1617
            I + D  +  E    R AFL   +  +Y++ +LRRAK SSM +LY LHN    AF   C 
Sbjct: 185  IEDKDNNLESEFFHNRQAFLNLCQGNNYQYETLRRAKHSSMMILYHLHNPTAPAFATVCT 244

Query: 1618 SCKAAVETR--YHCSTCDDFDLCVPCYNKEGHHHKMTKLGLGLDDIASSDKEENPQESRR 1675
             C+  VE    +HC  C  +D+C  CY+K+  +H   KL        S+  ++N Q S+ 
Sbjct: 245  ICQQEVENSQGWHCEVCPGYDVCSACYSKDSINHSH-KLTSRSSSTDSTVVQQNGQASQS 303

Query: 1676 KSI--QRCISSLVHACQCRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCC 1733
              +  ++    LVHA  CR+  C+   C K K +  H + C   T   CPICK L +L  
Sbjct: 304  YQVKLEKLKKLLVHAATCRSTQCQYQGCRKSKMLFRHCIDC---TTGDCPICKGLWSLLK 360

Query: 1734 YHAKHCVENKCQVPFCAXXXXXXXXXXXXTTLHQAQMLRRRVAIM 1778
             HA++C ++KC VP C+                Q    RRR A+M
Sbjct: 361  LHARNCRDSKCTVPKCSGLRAISRRK------QQQADKRRRAAVM 399
>gi|21105785|gb|AAM34790.1|AF512560_2 HAC4 [Arabidopsis thaliana]
          Length = 385

 Score =  123 bits (308), Expect = 4e-26
 Identities = 76/225 (33%), Positives = 109/225 (48%), Gaps = 14/225 (6%)

Query: 1558 ITEPDPAMSCELMDGRDAFLTTAREKHYEFSSLRRAKLSSMALLYELHNQGKDAFVYTCN 1617
            I + D  +  E    R AFL   +  +Y++ +LRRAK SSM +LY LHN    AF   C 
Sbjct: 157  IEDKDNNLESEFFHNRQAFLNLCQGNNYQYETLRRAKHSSMMILYHLHNPTAPAFATVCT 216

Query: 1618 SCKAAVETR--YHCSTCDDFDLCVPCYNKEGHHHKMTKLGLGLDDIASSDKEENPQESRR 1675
             C+  VE    +HC  C  +D+C  CY+K+  +H   KL        S+  ++N Q S+ 
Sbjct: 217  ICQQEVENSQGWHCEVCPGYDVCSACYSKDSINHSH-KLTSRSSSTDSTVVQQNGQASQS 275

Query: 1676 KSI--QRCISSLVHACQCRNANCRMNACHKMKRVVGHTMSCRRKTNNGCPICKQLIALCC 1733
              +  ++    LVHA  CR+  C+   C K K +  H + C   T   CPICK L +L  
Sbjct: 276  YQVKLEKLKKLLVHAATCRSTQCQYQGCRKSKMLFRHCIDC---TTGDCPICKGLWSLLK 332

Query: 1734 YHAKHCVENKCQVPFCAXXXXXXXXXXXXTTLHQAQMLRRRVAIM 1778
             HA++C ++KC VP C+                Q    RRR A+M
Sbjct: 333  LHARNCRDSKCTVPKCSGLRAISRRK------QQQADKRRRAAVM 371
>gi|17553334|ref|NP_499197.1| CREB-binding protein like family member (22.2 kD) (3L5)
           [Caenorhabditis elegans]
 gi|542476|pir||S42836 F40F12.7 protein - Caenorhabditis elegans
 gi|3877001|emb|CAA82938.1| Hypothetical protein F40F12.7 [Caenorhabditis elegans]
          Length = 199

 Score =  120 bits (302), Expect = 2e-25
 Identities = 59/97 (60%), Positives = 66/97 (68%), Gaps = 10/97 (10%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE----------QECKLPYCRTMKNVLNHMTT 328
           +P K KLIQQQ VLLLHAHKC +RE+ N E            C LP+C TMK VL HMT 
Sbjct: 7   DPVKRKLIQQQFVLLLHAHKCSQREKENNEFAARNQLLPHAACTLPHCSTMKEVLIHMTN 66

Query: 329 CNKGKSCEVAHCASSRQIITHWKNCLRQDCPVCFALK 365
           CN G+ C  AHCASSRQII HWK+C R+DCPVC  LK
Sbjct: 67  CNVGRLCHFAHCASSRQIIAHWKDCSREDCPVCKPLK 103
>gi|482238|pir||S41033 hypothetical protein K03H1.10 - Caenorhabditis elegans  (fragment)
          Length = 316

 Score =  104 bits (260), Expect = 2e-20
 Identities = 57/102 (55%), Positives = 76/102 (74%), Gaps = 6/102 (5%)

Query: 496 SIPVSSRKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARKVEGDMYE 555
           ++PV + K+WH QVT DLRNH+V KLV+AI P P+   + D R+K+L AYARKVE +++E
Sbjct: 155 NVPVRT-KEWHRQVTNDLRNHIVGKLVKAICPAPEM--MNDIRLKDLNAYARKVEKEVFE 211

Query: 556 SANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQNAPNAQVP 597
           +A +R  YYHLLAEKIY+IQKEL+EK+  R+   N   AQ P
Sbjct: 212 TAIDRKNYYHLLAEKIYEIQKELQEKKNSRL---NQGAAQSP 250

 Score = 99.8 bits (247), Expect = 6e-19
 Identities = 60/99 (60%), Positives = 68/99 (68%), Gaps = 10/99 (10%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE----------QECKLPYCRTMKNVLNHMTT 328
           +P K KL+QQQLVLLLHAHKC  R++ N E            C+LP+C TMK VL HMT 
Sbjct: 1   DPVKQKLVQQQLVLLLHAHKCSLRDKENNEFAARNQPLPHTTCRLPHCPTMKEVLIHMTN 60

Query: 329 CNKGKSCEVAHCASSRQIITHWKNCLRQDCPVCFALKIA 367
           CN G+ C  AHCASSRQII HWKNC R+DCPVC  LK A
Sbjct: 61  CNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCTPLKRA 99
>gi|17554044|ref|NP_499201.1| CREB-binding protein like family member (36.7 kD) (3L15)
           [Caenorhabditis elegans]
 gi|25395947|pir||D88569 protein K03H1.10 [imported] - Caenorhabditis elegans
 gi|3877003|emb|CAA82940.1| Hypothetical protein K03H1.10 [Caenorhabditis elegans]
 gi|3878179|emb|CAA82665.1| Hypothetical protein K03H1.10 [Caenorhabditis elegans]
          Length = 322

 Score =  104 bits (260), Expect = 2e-20
 Identities = 57/102 (55%), Positives = 76/102 (74%), Gaps = 6/102 (5%)

Query: 496 SIPVSSRKDWHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARKVEGDMYE 555
           ++PV + K+WH QVT DLRNH+V KLV+AI P P+   + D R+K+L AYARKVE +++E
Sbjct: 161 NVPVRT-KEWHRQVTNDLRNHIVGKLVKAICPAPEM--MNDIRLKDLNAYARKVEKEVFE 217

Query: 556 SANNRGQYYHLLAEKIYKIQKELEEKRIQRMKVQNAPNAQVP 597
           +A +R  YYHLLAEKIY+IQKEL+EK+  R+   N   AQ P
Sbjct: 218 TAIDRKNYYHLLAEKIYEIQKELQEKKNSRL---NQGAAQSP 256

 Score = 99.8 bits (247), Expect = 6e-19
 Identities = 60/99 (60%), Positives = 68/99 (68%), Gaps = 10/99 (10%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE----------QECKLPYCRTMKNVLNHMTT 328
           +P K KL+QQQLVLLLHAHKC  R++ N E            C+LP+C TMK VL HMT 
Sbjct: 7   DPVKQKLVQQQLVLLLHAHKCSLRDKENNEFAARNQPLPHTTCRLPHCPTMKEVLIHMTN 66

Query: 329 CNKGKSCEVAHCASSRQIITHWKNCLRQDCPVCFALKIA 367
           CN G+ C  AHCASSRQII HWKNC R+DCPVC  LK A
Sbjct: 67  CNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCTPLKRA 105
>gi|7494646|pir||T37269 hypothetical protein - Caenorhabditis elegans (fragment)
 gi|2665395|dbj|BAA23766.1| unnamed protein product [Caenorhabditis elegans]
          Length = 118

 Score =  103 bits (256), Expect = 5e-20
 Identities = 60/97 (61%), Positives = 69/97 (71%), Gaps = 10/97 (10%)

Query: 279 EPDKSKLIQQQLVLLLHAHKCQRREQNNIE----------QECKLPYCRTMKNVLNHMTT 328
           +P+K KLIQQQLVLLLHAHKC +RE+ N +            C LP+C TMK VL HMT+
Sbjct: 3   DPEKRKLIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTS 62

Query: 329 CNKGKSCEVAHCASSRQIITHWKNCLRQDCPVCFALK 365
           CN G+ C  AHCASSRQII HWKNC R+DCPVC  LK
Sbjct: 63  CNVGRLCHFAHCASSRQIIAHWKNCSREDCPVCKPLK 99
>gi|13699186|dbj|BAB41205.1| kinase-like protein [Oryza sativa]
          Length = 714

 Score = 96.3 bits (238), Expect = 6e-18
 Identities = 71/206 (34%), Positives = 98/206 (47%), Gaps = 15/206 (7%)

Query: 962  VGDASNNSAASTPKPRCKKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIPD 1021
            V  A      + P+P    V  +D + +     L+KL  Q   ++ F  PVD V L+IPD
Sbjct: 142  VRGAKGRFLPTKPRPEASTVLTEDAIFKQCDAILKKLMTQKCSNI-FDSPVDAVKLNIPD 200

Query: 1022 YFDIVKKPMDLSTIRRKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEV 1081
            YF I+KKPMDL TIR KLDSG Y+ P E+  DV L F NA  YN +   V+ YA +L+++
Sbjct: 201  YFQIIKKPMDLGTIRNKLDSGSYTSPSEFAADVRLTFSNAMTYNPRGHVVHDYAIQLNKM 260

Query: 1082 FESEIDSVMQSLGYCCGHKYV----------FCPQVLCCYGKQLCTIPRDSM--YYSYQN 1129
            FES   ++ + L       +V            P V C      C  P +S+    S + 
Sbjct: 261  FESRWRTIEKKLASIATEAHVEVDRADSKRRKTPPVDCSEVSTECVRPTESVRPTESVKP 320

Query: 1130 RYVYCEKCFNEIQTDEVELSEDPTQP 1155
            +  + EK           LSEDP  P
Sbjct: 321  KMTFEEK--ESFGNCLASLSEDPEVP 344
>gi|7493489|pir||T40984 transcription factor bdf1 homolog SPCC1450.02 - fission yeast
            (Schizosaccharomyces pombe)
 gi|4581512|emb|CAB40169.1| SPCC1450.02 [Schizosaccharomyces pombe]
          Length = 578

 Score = 90.5 bits (223), Expect = 3e-16
 Identities = 67/189 (35%), Positives = 91/189 (48%), Gaps = 21/189 (11%)

Query: 917  MDTGKSESEVKPEPDSIKAENETSSPKLDNLDESSQASIEEKP-----------ASVGDA 965
            M +   E+EVK E     A + +     DN  +SS    +E             A+VGD 
Sbjct: 1    MSSESRENEVKAETKDEIANDGSPQLNGDNNIQSSDGHNDENEESLSRKRDSSGATVGDL 60

Query: 966  SNNSAASTPKPRCKKVFDKDELRQALMPTLEKLF--------KQDPESLPFRQPVDPVVL 1017
                  S PK   +    K  +R + MP  ++ +        K+   S PF+ PVDP+  
Sbjct: 61   KQEEKESMPKKEPEPTVKK--IRGSGMPPPQQKYCLAIVRQLKRTKNSAPFKVPVDPIKQ 118

Query: 1018 HIPDYFDIVKKPMDLSTIRRKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASK 1077
            +IPDY  IVK PMDL TI +KL S  YS P E++DD+ LMF N +LYN   S V      
Sbjct: 119  NIPDYPTIVKNPMDLGTIEKKLTSYEYSVPQEFIDDMNLMFSNCFLYNGTESPVGSMGKA 178

Query: 1078 LSEVFESEI 1086
            L EVFE ++
Sbjct: 179  LQEVFERQL 187

 Score = 76.3 bits (186), Expect = 7e-12
 Identities = 57/181 (31%), Positives = 88/181 (48%), Gaps = 26/181 (14%)

Query: 923  ESEVKPEPDSIKAENETSSPKLDNLDESSQASIEEKPASV----------------GDAS 966
            E ++K  PD   AE   ++P    + +S Q S    P                       
Sbjct: 184  ERQLKQLPD---AEQPAAAP----VKKSKQKSASTAPPRTRRNSSVSSTSASVAASTAPK 236

Query: 967  NNSAASTPKPRCKKVFDKDELRQALMPTLEKLFKQDPES--LPFRQPVDPVVLHIPDYFD 1024
              S A  P+ + ++  +  ++R      L++L+K+  ES   PF QPVDPV    PDYFD
Sbjct: 237  AASPAVLPEGKPRRRKNNSQMR-FCSTVLKELYKRQYESFAFPFYQPVDPVACDCPDYFD 295

Query: 1025 IVKKPMDLSTIRRKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEVFES 1084
            ++K+PMDLSTI+ KL+   YS   E+  D+ LMF+N + YN   + V+    +L  VF+ 
Sbjct: 296  VIKEPMDLSTIQSKLNKNEYSTLEEFESDILLMFNNCFTYNPPGTPVHVMGRQLENVFKE 355

Query: 1085 E 1085
            +
Sbjct: 356  K 356
>gi|29569106|gb|AAO84020.1| global transcription factor group E [Zea mays]
          Length = 696

 Score = 88.2 bits (217), Expect = 2e-15
 Identities = 50/129 (38%), Positives = 72/129 (55%), Gaps = 1/129 (0%)

Query: 974  PKPRCKKVFDKDELRQALMPTLEKLFKQDPESLPFRQPVDPVVLHIPDYFDIVKKPMDLS 1033
            P+P    V  +    +     L+KL  Q    + F  PVD V L IPDYFDIVK PMDL 
Sbjct: 155  PRPETSTVLSEAAAFKQCEAILKKLMTQKYSHI-FNVPVDIVKLQIPDYFDIVKTPMDLG 213

Query: 1034 TIRRKLDSGLYSDPWEYVDDVCLMFDNAWLYNRKTSRVYKYASKLSEVFESEIDSVMQSL 1093
            T+++KL+SG Y+ P ++  DV L F+NA  YN +   V+  A +L+++FES    + + L
Sbjct: 214  TVKKKLESGSYTSPSDFAADVRLTFNNAMAYNPRGHAVHDMAIQLNKMFESRWRPIEKKL 273

Query: 1094 GYCCGHKYV 1102
                  K+V
Sbjct: 274  ASAATEKHV 282
  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF
    Posted date:  Sep 11, 2003  1:15 AM
  Number of letters in database: 490,308,901
  Number of sequences in database:  1,522,899
  
Lambda     K      H
   0.316    0.130    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 166,306,883
Number of Sequences: 1522899
Number of extensions: 6321964
Number of successful extensions: 17257
Number of sequences better than  1.0: 62
Number of HSP's better than  1.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 17072
Number of HSP's gapped (non-prelim): 147
length of query: 2245
length of database: 490,308,901
effective HSP length: 140
effective length of query: 2105
effective length of database: 277,103,041
effective search space: 583301901305
effective search space used: 583301901305
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 90 (39.3 bits)