HumanPRENbase
Database of Prenylated Human
Proteins and their Orthologues
Protein CaaX Farnesylation, CaaX Geranylgeranylation and Rab Geranylgeranylation

CLUSTER parameter selection

REQUIRE one of the features for at least one member of listed clusters:
Status-KNOWN Status-LIKELY Status-NEW FT-substrate(s)
EXCLUDE clusters with the following features for at least one member:
Status-OUT-OF-CONTEXT GGT1-substrate(s) GGT2-substrate(s)
Other features for cluster members are ALLOWED.
Minimum cluster-size: 1

SEQUENCE parameter selection

INCLUDE entries with the following features:
Viruses Mammalia Aves Amphibia Fishes Insecta Nematoda Fungi Plants Other-Eukaryota
EXCLUDE entries with the following features:
Synthetic-constructs
Ranked by evOluation of cluster after selection

Querycode: Hcs2220ce200ct11111111111111cm1se111st00202222222221r3 (save for easy recovery of the identical query parameters)
 Clusters  Selected Sequences
General Information Stats Stats Enzyme Taxonomic Kingdom Taxonomic Detail Eukaryota
Status Rank ClustID Name Pren Total PC EvO Number PC EvO FT GGT1 GGT2 Viruses Synthetic Eukaryota Mammalia Birds Amphibia Fishes Insecta Nematoda Fungi Plants Other
+ 1 21327708
(no isoinpas)		 nucleosome assembly protein 1-like 1 25 41 11.500 15.244 25
Explore		 11.500 15.244 25 0 0 0 0 25 3 1 2 1 0 0 11 7 0
+ 2 23308519
(3 isoinpas)		 prickle-like 1 9 9 3.750 9.000 9
Explore		 3.750 9.000 9 0 0 0 0 9 4 1 1 2 0 1 0 0 0
+ 3 4505783
(2 isoinpas)		 phosphorylase kinase, beta 13 19 4.583 8.895 13
Explore		 4.583 8.895 13 0 0 0 0 13 6 1 0 1 3 2 0 0 0
+ 4 55665085
(2 isoinpas)		 BRO1/Rhophilin-like domain 9 11 3.000 7.364 9
Explore		 3.000 7.364 9 0 0 0 0 9 5 1 0 2 0 1 0 0 0
+ 5 4092830
(2 isoinpas)		 DEXRAS2, RASD2, Rhes 7 7 2.333 7.000 7
Explore		 2.333 7.000 7 0 0 0 0 7 4 1 1 0 1 0 0 0 0
+ 6 2695592
(2 isoinpas)		 photoreceptor transducin gamma subunit T1 7 8 1.750 6.125 7
Explore		 1.750 6.125 7 0 0 0 0 7 4 0 1 2 0 0 0 0 0
* 7 4757770
(no isoinpas)		 RhoH - Rho-related GTP-binding protein 6 7 1.500 5.143 6
Explore		 1.500 5.143 6 0 0 0 0 6 4 1 0 1 0 0 0 0 0
+ 8 51460469
(6 isoinpas)		 RhoQ - Rho-related GTP-binding protein, TC10 5 5 1.250 5.000 5
Explore		 1.250 5.000 5 0 0 0 0 5 2 1 0 2 0 0 0 0 0
+ 9 4758994
(2 isoinpas)		 RAB28, member RAS oncogene family isoform 2 5 5 1.250 5.000 5
Explore		 1.250 5.000 5 0 0 0 0 5 2 0 0 0 1 2 0 0 0
+ 10 14589849
(no isoinpas)		 G protein, gamma 2, transducing activity 5 5 0.833 5.000 5
Explore		 0.833 5.000 5 0 0 0 0 5 4 0 0 1 0 0 0 0 0
? 11 45501001
(4 isoinpas)		 EHBP1 - EH domain binding protein 1 7 11 1.167 4.455 7
Explore		 1.167 4.455 7 0 0 0 0 7 4 0 0 0 3 0 0 0 0
* 12 50949371
(7 isoinpas)		 hypothetical coiled-coil protein 5 6 0.667 4.167 5
Explore		 0.667 4.167 5 0 0 0 0 5 4 0 0 1 0 0 0 0 0
? 13 17402931
(2 isoinpas)		 sperm associated antigen 11 isoform C precursor, secreted, similarity to beta-defensins = cysteine used as disulfide bridge? 4 4 0.333 4.000 4
Explore		 0.333 4.000 4 0 0 0 0 4 4 0 0 0 0 0 0 0 0
* 14 21758015
(6 isoinpas)		 DnaJA4 - DnaJ/Hsp40 homolog, subfamily A, member 4 10 25 5.000 4.000 10
Explore		 5.000 4.000 10 0 0 1 0 9 5 1 0 0 1 1 0 0 1
? 15 50960731
(2 isoinpas)		 DEAQ box polypeptide 1 RNA-dependent ATPase 4 4 0.333 4.000 4
Explore		 0.333 4.000 4 0 0 0 0 4 4 0 0 0 0 0 0 0 0
+ 16 4507271
(2 isoinpas)		 LKB1 - serine/threonine protein kinase 11 7 13 2.333 3.769 7
Explore		 2.333 3.769 7 0 0 0 0 7 4 0 1 1 0 0 0 0 1
* 17 38327539
(2 isoinpas)		 72kDa inositol polyphosphate-5-phosphatase E 5 7 1.250 3.571 5
Explore		 1.250 3.571 5 0 0 0 0 5 2 1 0 0 2 0 0 0 0
? 18 50949308
(3 isoinpas)		 hypothetical protein DPCD 6 11 1.500 3.273 6
Explore		 1.500 3.273 6 0 0 0 0 6 4 1 0 1 0 0 0 0 0
? 19 41018470
(3 isoinpas)		 WD and tetratricopeptide repeats protein 1 7 15 3.000 3.267 7
Explore		 3.000 3.267 7 0 0 0 0 7 2 1 0 1 0 1 1 1 0
+ 20 4506263
(no isoinpas)		 prostaglandin I2 prostacyclin receptor IP 4 5 0.250 3.200 4
Explore		 0.250 3.200 4 0 0 0 0 4 4 0 0 0 0 0 0 0 0
* 21 4758690
(3 isoinpas)		 leucine rich repeat in FLII interacting protein 1 4 5 0.333 3.200 4
Explore		 0.333 3.200 4 0 0 0 0 4 4 0 0 0 0 0 0 0 0
? 22 22062496
(3 isoinpas)		 tangerin, calponin homology domain 3 3 0.250 3.000 3
Explore		 0.250 3.000 3 0 0 0 0 3 3 0 0 0 0 0 0 0 0
* 23 31559833
(no isoinpas)		 E-Ras, small GTPase 3 3 0.250 3.000 3
Explore		 0.250 3.000 3 0 0 0 0 3 3 0 0 0 0 0 0 0 0
? 24 34783118
(5 isoinpas)		 DEAD/H Asp-Glu-Ala-Asp/His box polypeptide 32 4 6 0.667 2.667 4
Explore		 0.667 2.667 4 0 0 0 0 4 3 0 1 0 0 0 0 0 0
* 25 7710129
(3 isoinpas)		 LIM domain only 6 4 6 0.250 2.667 4
Explore		 0.250 2.667 4 0 0 0 0 4 4 0 0 0 0 0 0 0 0
? 26 13124858
(2 isoinpas)		 stoned B-like factor SBLF, stonin 1 4 7 0.333 2.286 4
Explore		 0.333 2.286 4 0 0 0 0 4 4 0 0 0 0 0 0 0 0
* 27 21361653
(2 isoinpas)		 hypothetical coiled-coil protein FLJ20364 4 8 0.667 2.000 4
Explore		 0.667 2.000 4 0 0 0 0 4 3 1 0 0 0 0 0 0 0
? 28 30353973
(no isoinpas)		 Similar to N-terminus of solute carrier family 34 sodium phosphate, member 3 2 2 0.167 2.000 2
Explore		 0.167 2.000 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
? 29 51477353
(no isoinpas)		 WD40 repeats, similar to H326, WDR42A 2 2 0.167 2.000 2
Explore		 0.167 2.000 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
? 30 47117499
(3 isoinpas)		 Zinc finger CCCH type antiviral protein 1, Zinc finger CCCH type domain containing protein 2 3 5 0.167 1.800 3
Explore		 0.167 1.800 3 0 0 0 0 3 3 0 0 0 0 0 0 0 0
? 31 34535072
(4 isoinpas)		 Arrestin N- and C-terminal domains 5 14 1.000 1.786 5
Explore		 1.000 1.786 5 0 0 0 0 5 2 0 2 1 0 0 0 0 0
+ 32 627477
(4 isoinpas)		 INPP5A - inositol-polyphosphate 5-phosphatase EC 3.1.3. 5 15 1.250 1.667 5
Explore		 1.250 1.667 5 0 0 0 0 5 3 1 1 0 0 0 0 0 0
? 33 4503113
(2 isoinpas)		 cystatin M precursor 4 10 0.333 1.600 4
Explore		 0.333 1.600 4 0 0 0 0 4 4 0 0 0 0 0 0 0 0
+ 34 1246236
(3 isoinpas)		 PTP-IV1b, protein tyrosine phosphatase 3 6 0.333 1.500 3
Explore		 0.333 1.500 3 0 0 0 0 3 2 0 1 0 0 0 0 0 0
? 35 22658314
(2 isoinpas)		 FAM83F, phospholipase D domain hit 3 6 0.250 1.500 3
Explore		 0.250 1.500 3 0 0 0 0 3 3 0 0 0 0 0 0 0 0
+ 36 55770834
(4 isoinpas)		 centromere protein F 350/400kD 4 11 0.667 1.455 4
Explore		 0.667 1.455 4 0 0 0 0 4 3 1 0 0 0 0 0 0 0
? 37 20562230
(no isoinpas)		 PREDICTED: similar to caspase 14-like protein 2 3 0.167 1.333 2
Explore		 0.167 1.333 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
? 38 37182964
(3 isoinpas)		 ECEL1 - metallopeptidase 5 20 1.250 1.250 5
Explore		 1.250 1.250 5 0 0 0 0 5 3 0 1 1 0 0 0 0 0
? 39 20270357
(no isoinpas)		 similar to Arsenite inducible RNA associated protein 4 13 0.667 1.231 4
Explore		 0.667 1.231 4 0 0 0 0 4 3 0 0 1 0 0 0 0 0
? 40 51471094
(no isoinpas)		 low complexity, proline-rich, PREDICTED: hypothetical protein XP_378365 1 1 0.083 1.000 1
Explore		 0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 41 11360231
(no isoinpas)		 hypothetical protein DKFZp761E13121.1 fragment 1 1 0.000 1.000 1
Explore		 0.000 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 42 37182490
(no isoinpas)		 C-terminal variant of transmembrane Crumbs protein homolog 3 precursor 2 4 0.167 1.000 2
Explore		 0.167 1.000 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
? 43 21754420
(no isoinpas)		 similar to At2g27390 1 1 0.083 1.000 1
Explore		 0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 44 7690063
(no isoinpas)		 aniridia protein, PAX6 fragment truncated through premature translational termination mutations 1 1 0.083 1.000 1
Explore		 0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 45 34533082
(no isoinpas)		 unnamed protein, similar to BT2029 from Bacteroides thetaiotaomicron 1 1 0.083 1.000 1
Explore		 0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
* 46 12060820
(no isoinpas)		 serologically defined breast cancer antigen NY-BR-15, coiled coil 1 1 0.083 1.000 1
Explore		 0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 47 47077088
(no isoinpas)		 unnamed protein 1 1 0.083 1.000 1
Explore		 0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 48 28193148
(no isoinpas)		 C14orf167 1 1 0.083 1.000 1
Explore		 0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 49 51477210
(no isoinpas)		 brain expressed X-linked-like 1 1 1 0.083 1.000 1
Explore		 0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
* 50 27501389
(no isoinpas)		 similar to RAC1 RAS-related C3 botulinum toxin substrate 1 1 1 0.083 1.000 1
Explore		 0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 51 42660066
(no isoinpas)		 PREDICTED: hypothetical protein XP_378394 1 1 0.083 1.000 1
Explore		 0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 52 41151611
(no isoinpas)		 WD40 repeats, WDR42B 1 1 0.083 1.000 1
Explore		 0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 53 27479553
(no isoinpas)		 PREDICTED: hypothetical protein XP_211089 1 1 0.083 1.000 1
Explore		 0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 54 3540176
(no isoinpas)		 F23269_1, partial CDS 1 1 0.083 1.000 1
Explore		 0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 55 34531647
(no isoinpas)		 unnamed protein 1 1 0.083 1.000 1
Explore		 0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 56 51492807
(2 isoinpas)		 PREDICTED: hypothetical protein XP_380155 1 1 0.083 1.000 1
Explore		 0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 57 5174461
(2 isoinpas)		 G protein-coupled receptor 109B, seven transmembrane helix 2 5 0.167 0.800 2
Explore		 0.167 0.800 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
? 58 40674056
(2 isoinpas)		 N-terminus contains part of Formin homology domain 2, C14orf173 protein 2 5 0.167 0.800 2
Explore		 0.167 0.800 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
? 59 4557335
(no isoinpas)		 aspartoacylase 3 14 0.250 0.643 3
Explore		 0.250 0.643 3 0 0 0 0 3 3 0 0 0 0 0 0 0 0
? 60 27262649
(2 isoinpas)		 ataxin 2 related protein isoform C 3 14 0.250 0.643 3
Explore		 0.250 0.643 3 0 0 0 0 3 3 0 0 0 0 0 0 0 0
? 61 51475774
(2 isoinpas)		 von Willebrand factor type A + BPTI/Kunitz family serine protease inhibitor domains 2 7 0.167 0.571 2
Explore		 0.167 0.571 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
+ 62 4502781
(2 isoinpas)		 centromere protein E 3 16 0.500 0.562 3
Explore		 0.500 0.562 3 0 0 0 0 3 2 0 1 0 0 0 0 0 0
? 63 51466681
(no isoinpas)		 similar to N-terminus of putative eukaryotic translation initiation factor 3 subunit (eIF-3 1 2 0.083 0.500 1
Explore		 0.083 0.500 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 64 34530046
(no isoinpas)		 unnamed protein, shares 24 N-terminal residues with Asialoglycoprotein receptor 1 1 2 0.083 0.500 1
Explore		 0.083 0.500 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 65 51470845
(no isoinpas)		 PREDICTED: hypothetical protein XP_498512 1 2 0.083 0.500 1
Explore		 0.083 0.500 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 66 45708550
(no isoinpas)		 DUF872 1 3 0.083 0.333 1
Explore		 0.083 0.333 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 67 51476980
(no isoinpas)		 N-terminal fragment of Piwi-like 4, PAZ domain, RNAI pathway 1 3 0.083 0.333 1
Explore		 0.083 0.333 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 68 51466249
(no isoinpas)		 similar to vomeronasal putative G-protein coupled receptor 1 3 0.083 0.333 1
Explore		 0.083 0.333 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
* 69 32171177
(no isoinpas)		 OEBT over-expressed breast tumor LIM protein 1 4 0.083 0.250 1
Explore		 0.083 0.250 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 70 51464670
(no isoinpas)		 similar to hypothetical protein L1H 3 region 1 4 0.083 0.250 1
Explore		 0.083 0.250 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 71 24497591
(no isoinpas)		 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit isoform 2 1 5 0.083 0.200 1
Explore		 0.083 0.200 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 72 18676548
(no isoinpas)		 FLJ00171 protein, contains N-terminal half of UhpC, Sugar phosphate permease domain 2 23 0.167 0.174 2
Explore		 0.167 0.174 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
+ 73 38606970
(4 isoinpas)		 phospholipase A2, group IVC cytosolic, calcium-independent 1 6 0.083 0.167 1
Explore		 0.083 0.167 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 74 16307060
(no isoinpas)		 Clathrin adaptor complex small chain, AP1S3 protein 1 6 0.083 0.167 1
Explore		 0.083 0.167 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 75 37678114
(no isoinpas)		 voltage-gated calcium channel beta 1 subunit splice variant CavB1d, contains SH3 domain 1 6 0.083 0.167 1
Explore		 0.083 0.167 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 76 39918780
(no isoinpas)		 synaptotagmin 14 splice variant 1 1 7 0.083 0.143 1
Explore		 0.083 0.143 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 77 7385003
(no isoinpas)		 integrin alpha 10 subunit 1 7 0.083 0.143 1
Explore		 0.083 0.143 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 78 31874655
(no isoinpas)		 fragment of IL2-inducible T-cell kinase 1 7 0.083 0.143 1
Explore		 0.083 0.143 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 79 33150550
(no isoinpas)		 possible Armadillo-repeat 1 10 0.083 0.100 1
Explore		 0.083 0.100 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 80 20336253
(no isoinpas)		 palmitoyl-protein thioesterase 2 isoform c precursor 1 11 0.083 0.091 1
Explore		 0.083 0.091 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 81 28279804
(no isoinpas)		 Non-catalytic N-terminus of Alpha-2,8-sialyltransferase 8A 1 13 0.083 0.077 1
Explore		 0.083 0.077 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 82 11360251
(no isoinpas)		 hypothetical DKFZp761K2213.1 fragment - FHA, DIL, PDZ domain 1 15 0.083 0.067 1
Explore		 0.083 0.067 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 83 46361987
(no isoinpas)		 hydroxyacylglutathione hydrolase-like isoform 1 1 21 0.083 0.048 1
Explore		 0.083 0.048 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 84 8922413
(no isoinpas)		 hypothetical protein FLJ10415 1 26 0.083 0.038 1
Explore		 0.083 0.038 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 85 15929807
(no isoinpas)		 FLJ20125 protein, contains N-terminal half of Integrase core domain 1 27 0.083 0.037 1
Explore		 0.083 0.037 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 86 1374863
(2 isoinpas)		 CoxII/D-loop DNA fusion protein 1 70 0.000 0.014 1
Explore		 0.000 0.014 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 87 31871818
(no isoinpas)		 interleukin-1 receptor associated kinase 4 mutant form 1 1 84 0.083 0.012 1
Explore		 0.083 0.012 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0

Your query selected 277 sequences in 87 clusters.