ID GBA1_CRYPA STANDARD; PRT; 352 AA. AC Q00580; DT 01-NOV-1997 (Rel. 35, Created) DT 01-NOV-1997 (Rel. 35, Last sequence update) DT 01-NOV-1997 (Rel. 35, Last annotation update) DE GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA SUBUNIT. OS Cryphonectria parasitica (Chesnut blight fungus) OS (Endothia parasitica). OC Eukaryota; Fungi; Ascomycota; Diaporthales; Valsaceae; Cryphonectria. OX NCBI_TaxID=5116; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=EP155; RX MEDLINE=95116547; PubMed=7816838; RA Choi G.H., Chen B., Nuss D.L.; RT "Virus-mediated or transgenic suppression of a G-protein alpha subunit RT and attenuation of fungal virulence."; RL Proc. Natl. Acad. Sci. U.S.A. 92:305-309(1995). CC -!- FUNCTION: GUANINE NUCLEOTIDE-BINDING PROTEINS (G PROTEINS) ARE CC INVOLVED AS MODULATORS OR TRANSDUCERS IN VARIOUS TRANSMEMBRANE CC SIGNALING SYSTEMS. CC -!- SUBUNIT: G PROTEINS ARE COMPOSED OF 3 UNITS (ALPHA, BETA & GAMMA). CC THE ALPHA CHAIN CONTAINS THE GUANINE NUCLEOTIDE BINDING SITE. CC -!- SIMILARITY: BELONGS TO THE G-ALPHA FAMILY. SUBFAMILY 3 (G(Q)). CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- DR EMBL; L32176; AAA67706.1; -. DR HSSP; P04896; 1AZT. DR INTERPRO; IPR001019; -. DR INTERPRO; IPR002975; -. DR PFAM; PF00503; G-alpha; 1. DR PRINTS; PR00318; GPROTEINA. DR PRINTS; PR01241; GPROTEINAFNG. KW GTP-binding; Transducer; Myristate. FT INIT_MET 0 0 BY SIMILARITY. FT LIPID 1 1 MYRISTATE (BY SIMILARITY). FT NP_BIND 40 47 GTP (BY SIMILARITY). FT NP_BIND 199 202 GTP (BY SIMILARITY). FT NP_BIND 268 271 GTP (BY SIMILARITY). SQ SEQUENCE 352 AA; 40917 MW; 710B6CB3BE391D6F CRC64; GCGMSTEEKE GKARNEEIEN QLKRDRMQQR NEIKMLLLGA GESGKSTILK QMKLIHEGGY SRDERESFKE IIFSNTVQSM RVILEAMESL ELPLEDQRME YHVQTIFMQP AQIEGDVLPP EVGSAIEALW KDRGVQECFK RSREYQLNDS ARYYFDNIAR IAAPDYMPND QDVLRSRVKT TGITETTFII GDLTYRMFDV GGQRSERKKW IHCFENVTTI LFLVAISEYD QLLFEDETVN RMQEALTLFD SICNSRWFIK TSIILFLNKI DRFKEKLPVS PMKNYFPDYE GGDDYAAACD YILNRFVSLN QHETKQIYTH FTCATDTTQI RFVMAAVNDI IIQENLRLCG LI //