ID   FOL2_MOUSE     STANDARD;      PRT;   251 AA.
AC   Q05685;
DT   01-JUN-1994 (REL. 29, CREATED)
DT   01-JUN-1994 (REL. 29, LAST SEQUENCE UPDATE)
DT   01-OCT-1996 (REL. 34, LAST ANNOTATION UPDATE)
DE   FOLATE RECEPTOR BETA PRECURSOR (FR-BETA) (FOLATE RECEPTOR 2) (FOLATE-
DE   BINDING PROTEIN 2).
GN   FOLR2 OR FOLBP2 OR FBP2.
OS   MUS MUSCULUS (MOUSE).
OC   EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA;
OC   EUTHERIA; RODENTIA.
RN   [1]
RP   SEQUENCE FROM N.A.
RX   MEDLINE; 91373339.
RA   BRIGLE K.E., WESTIN E.H., HOUGHTON M.T., GOLDMAN I.D.;
RL   J. BIOL. CHEM. 266:17243-17249(1991).
RN   [2]
RP   SEQUENCE OF 1-49 FROM N.A.
RX   MEDLINE; 94140851.
RA   BRIGLE K.E., SEITHER R.L., WESTIN E.H., GOLDMAN I.D.;
RL   J. BIOL. CHEM. 269:4267-4272(1994).
CC   -!- FUNCTION: BINDS TO FOLATE AND REDUCED FOLIC ACID DERIVATIVES AND
CC       MEDIATES DELIVERY OF 5-METHYLTETRAHYDROFOLATE TO THE INTERIOR OF
CC       CELLS.
CC   -!- SUBCELLULAR LOCATION: ATTACHED TO THE MEMBRANE BY A GPI-ANCHOR
CC       (BY SIMILARITY).
CC   -!- PTM: EIGHT DISULFIDE BONDS ARE PRESENT (PROBABLE).
CC   -!- SIMILARITY: BELONGS TO THE FOLATE RECEPTOR FAMILY.
DR   EMBL; M64817; G193235; -.
DR   EMBL; L25338; G473468; -.
DR   PIR; B40969; B40969.
DR   MGD; MGI:95569; FOLBP2.
KW   RECEPTOR; GLYCOPROTEIN; SIGNAL; PLACENTA; FOLATE-BINDING; MEMBRANE;
KW   GPI-ANCHOR; MULTIGENE FAMILY.
FT   SIGNAL        1     20       POTENTIAL.
FT   CHAIN        21    227       FOLATE RECEPTOR BETA.
FT   PROPEP      228    251       REMOVED IN MATURE FORM (POTENTIAL).
FT   LIPID       227    227       GPI-ANCHOR (POTENTIAL).
FT   CARBOHYD     62     62       POTENTIAL.
FT   CARBOHYD    193    193       POTENTIAL.
SQ   SEQUENCE   251 AA;  28821 MW;  0F50571D CRC32;
     MAWKQTPLLL LVYMVTTGSG RDRTDLLNVC MDAKHHKTKP GPEDKLHDQC SPWKKNACCS
     VNTSQELHKA DSRLYFNWDH CGKMEPACKS HFIQDSCLYE CSPNLGPWIQ QVDQSWRKER
     FLDVPLCKED CHQWWEACRT SFTCKRDWHK GWDWSSGINK CPNTAPCHTF EYYFPTPASL
     CEGLWSHSYK VSNYSRGSGR CIQMWFDSTQ GNPNEDVVKF YASFMTSGTV PHAAVLLVPS
     LAPVLSLWLP G
//