ID   CD59_RAT       STANDARD;      PRT;   126 AA.
AC   P27274;
DT   01-AUG-1992 (REL. 23, CREATED)
DT   01-NOV-1997 (REL. 35, LAST SEQUENCE UPDATE)
DT   01-NOV-1997 (REL. 35, LAST ANNOTATION UPDATE)
DE   CD59 GLYCOPROTEIN PRECURSOR (MEMBRANE ATTACK COMPLEX INHIBITION
DE   FACTOR) (MACIF) (MAC-INHIBITORY PROTEIN) (MAC-IP) (PROTECTIN).
GN   CD59.
OS   RATTUS NORVEGICUS (RAT).
OC   EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA;
OC   EUTHERIA; RODENTIA.
RN   [1]
RP   SEQUENCE FROM N.A., AND SEQUENCE OF 23-64.
RC   STRAIN=SPRAGUE-DAWLEY; TISSUE=KIDNEY;
RX   MEDLINE; 95091697.
RA   RUSHMERE N.K., HARRISON R.A., DEN BERG C.W., MORGAN B.P.;
RL   BIOCHEM. J. 304:595-601(1994).
RN   [2]
RP   SEQUENCE OF 23-37.
RC   TISSUE=ERYTHROCYTE;
RX   MEDLINE; 92286999.
RA   HUGHES T.R., PIDDLESDEN S.J., WILLAMS J.D., HARRISON R.A.,
RA   MORGAN B.P.;
RL   BIOCHEM. J. 284:169-176(1992).
CC   -!- FUNCTION: POTENT INHIBITOR OF THE COMPLEMENT MEMBRANE ATTACK
CC       COMPLEX (MAC) ACTION. ACTS AT OR AFTER THE C5B-8 STAGE OF MAC
CC       ASSEMBLY.
CC   -!- SUBCELLULAR LOCATION: ATTACHED TO THE MEMBRANE BY A GPI-ANCHOR.
CC   -!- PTM: N-GLYCOSYLATED.
CC   -!- SIMILARITY: CONTAINS 1 UPAR/LY6 DOMAIN.
DR   EMBL; U48255; G1199655; -.
DR   PROSITE; PS00983; LY6_UPAR; 1.
KW   ANTIGEN; GLYCOPROTEIN; GPI-ANCHOR; SIGNAL.
FT   SIGNAL        1     22
FT   CHAIN        23    101       CD59 GLYCOPROTEIN.
FT   PROPEP      102    126       REMOVED IN MATURE FORM (BY SIMILARITY).
FT   LIPID       101    101       GPI-ANCHOR (BY SIMILARITY).
FT   DOMAIN       23    110       UPAR/LY6.
FT   DISULFID     25     48       BY SIMILARITY.
FT   DISULFID     28     35       BY SIMILARITY.
FT   DISULFID     41     61       BY SIMILARITY.
FT   DISULFID     67     85       BY SIMILARITY.
FT   DISULFID     86     91       BY SIMILARITY.
FT   CARBOHYD     38     38       POTENTIAL.
SQ   SEQUENCE   126 AA;  13790 MW;  4A651AAB CRC32;
     MRARRGFILL LLLAVLCSTG VSLRCYNCLD PVSSCKTNST CSPNLDACLV AVSGKQVYQQ
     CWRFSDCNAK FILSRLEIAN VQYRCCQADL CNKSFEDKPN NGAISLLGKT ALLVTSVLAA
     ILKPCF
//