Sequences with E-value BETTER than threshold (0.002) 1135 0.0
764 0.0
752 0.0
751 0.0
746 0.0
738 0.0
737 0.0
719 0.0
621 e-176
600 e-170
597 e-169
590 e-167
555 e-156
528 e-148
469 e-130
451 e-125
422 e-116
414 e-114
344 5e-93
321 2e-86
311 4e-83
309 1e-82
309 1e-82
305 2e-81
305 2e-81
305 2e-81
300 9e-80
298 3e-79
296 1e-78
291 3e-77
290 5e-77
290 5e-77
287 5e-76
284 4e-75
283 1e-74
282 2e-74
280 9e-74
279 2e-73
278 3e-73
277 5e-73
276 1e-72
276 2e-72
276 2e-72
276 2e-72
276 2e-72
274 4e-72
274 6e-72
274 6e-72
198 4e-49
Alignments
>ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan class N short form
[Arabidopsis thaliana]
gb|AAF24617.1|AC010870_10 (AC010870) putative phosphatidylinositolglycan class N short form
[Arabidopsis thaliana]
Length = 921
Score = 1135 bits (2906), Expect = 0.0
Identities = 921/921 (100%), Positives = 921/921 (100%)
Query: 1 MFLVGELGRSMRSDGILGVGGSDQSRATAVVVASRRRWLKRRETWLVVLGVALHAVYMLS 60
MFLVGELGRSMRSDGILGVGGSDQSRATAVVVASRRRWLKRRETWLVVLGVALHAVYMLS
Sbjct: 1 MFLVGELGRSMRSDGILGVGGSDQSRATAVVVASRRRWLKRRETWLVVLGVALHAVYMLS 60
Query: 61 IFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNII 120
IFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNII
Sbjct: 61 IFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNII 120
Query: 121 KNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFNQSRHTFAFG 180
KNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFNQSRHTFAFG
Sbjct: 121 KNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFNQSRHTFAFG 180
Query: 181 SPDIIPIFCSALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLH 240
SPDIIPIFCSALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLH
Sbjct: 181 SPDIIPIFCSALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLH 240
Query: 241 QDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTA 300
QDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTA
Sbjct: 241 QDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTA 300
Query: 301 DHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYD 360
DHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYD
Sbjct: 301 DHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYD 360
Query: 361 WGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGYMKLNEAEEVEAVVANTKQIL 420
WGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGYMKLNEAEEVEAVVANTKQIL
Sbjct: 361 WGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGYMKLNEAEEVEAVVANTKQIL 420
Query: 421 NQLLRKSYIKSSNSLFFKPFKPLVHHSFSLSQIDELISAKSYEAAMKLAVDLRNLSLEGL 480
NQLLRKSYIKSSNSLFFKPFKPLVHHSFSLSQIDELISAKSYEAAMKLAVDLRNLSLEGL
Sbjct: 421 NQLLRKSYIKSSNSLFFKPFKPLVHHSFSLSQIDELISAKSYEAAMKLAVDLRNLSLEGL 480
Query: 481 HYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAIL 540
HYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAIL
Sbjct: 481 HYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAIL 540
Query: 541 SVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAV 600
SVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAV
Sbjct: 541 SVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAV 600
Query: 601 VIVELLVHSFTERKLYTWFFLIAGVVASILLHFSIPWRSGIPVFVCISCWFLSVFTLMPA 660
VIVELLVHSFTERKLYTWFFLIAGVVASILLHFSIPWRSGIPVFVCISCWFLSVFTLMPA
Sbjct: 601 VIVELLVHSFTERKLYTWFFLIAGVVASILLHFSIPWRSGIPVFVCISCWFLSVFTLMPA 660
Query: 661 EIPDNNNLVSPFLGANDTDIFGWCVICDGVFVDKASNAESRIAFVTSVHKLVSCRYEAVF 720
EIPDNNNLVSPFLGANDTDIFGWCVICDGVFVDKASNAESRIAFVTSVHKLVSCRYEAVF
Sbjct: 661 EIPDNNNLVSPFLGANDTDIFGWCVICDGVFVDKASNAESRIAFVTSVHKLVSCRYEAVF 720
Query: 721 YSALAVVLMAWILFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMV 780
YSALAVVLMAWILFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMV
Sbjct: 721 YSALAVVLMAWILFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMV 780
Query: 781 LFNVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKL 840
LFNVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKL
Sbjct: 781 LFNVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKL 840
Query: 841 VRVPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVSAQVVFVLLLFALT 900
VRVPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVSAQVVFVLLLFALT
Sbjct: 841 VRVPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVSAQVVFVLLLFALT 900
Query: 901 NLYTRSIRIKPLSTSPSLKTL 921
NLYTRSIRIKPLSTSPSLKTL
Sbjct: 901 NLYTRSIRIKPLSTSPSLKTL 921
>gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melanogaster]
Length = 919
Score = 764 bits (1953), Expect = 0.0
Identities = 202/946 (21%), Positives = 372/946 (38%), Gaps = 144/946 (15%)
Query: 48 VLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFS---EPPAKRLVLLISDGLRADKFFE 104
+ + +H + + SI IYF++ I+ ++P+ EPPA RLV+ + DGLRA
Sbjct: 4 IQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSVLA 63
Query: 105 PDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPV 164
P LR + Q G+S A PPT +RPGH+AI GF EDP+A NP
Sbjct: 64 DHCSA---VPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAA---TLTWNPS 117
Query: 165 EFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTWNSYPHEYEDFA----TDASFLDEWSFD 220
FDSVFN+SR+ + ++ +F P +E FA +D LD+W+FD
Sbjct: 118 TFDSVFNRSRNAIGWMQAEVAKVFTHL----PTGGAPLRFETFARSDISDRLRLDQWTFD 173
Query: 221 QFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAER 280
+ + ++ L ++ F++L D H H P S + + + +
Sbjct: 174 KVRNFMTNE---QNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQ 230
Query: 281 VYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSH 340
Y L E + D+RT+Y+ TAD+G+S HG G +TP + WGAG++ P G +
Sbjct: 231 TYELFESVFNDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRSAPNPGQNF 287
Query: 341 SDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGY 400
++ +P + Q +APLMS L+GLP P+N++ +PLG+
Sbjct: 288 ------TAGENGPILPLYQ-----------LEQIQLAPLMSALIGLPPPMNNMALMPLGF 330
Query: 401 MKLNEAEEVEAVVANTKQILNQ--LLRKSYIKSSNSLFFKPFKPLVH--HSFSLSQIDEL 456
+ + E++ + N Q+L Q +L K + L F+ L I L
Sbjct: 331 LNTSVQYELQVLHLNAMQLLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYL 390
Query: 457 ISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSS 516
++ + YE A+K++ + L+ E + Y+ Y L L+ T Y W +L + + + S+
Sbjct: 391 VAKEQYEEALKVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWFYLLLVRLAR-ESN 449
Query: 517 LSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRLI-R 575
K + CL +L L +++ P L Y+ + + +E R
Sbjct: 450 HPKSERKGYLTWTTLMMCLGGLVLLELMILQRVPHLTAFYLLLPFGILILALAERPCQDR 509
Query: 576 GLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFLIAGVVASILLHFSI 635
L + + + ++ LL+ +L + + F
Sbjct: 510 DLM---CQFPVLHLVGIVMPGV-------LLILMAFHNSHIGLLYLPIVCLNNRRAFFR- 558
Query: 636 PWRSGIPVFVCISCWFLS----------------------------VFTLM-----PAEI 662
S +F + LS F+++ P +
Sbjct: 559 --PSLKLIFWLALVFLLSGILLVKQSASLHFITDTIGVYIGNSHVVYFSMILSIIRPLIL 616
Query: 663 PDNNNLVSPFLG-ANDTD--------------------------IFGWCVICDGVFVDKA 695
++ + A +F + I D
Sbjct: 617 GHQHSTRVWIVNMAALLVTAYGIYQWDADQPVCTYVYAACWSYLLFAFLSIPYSGTKDLR 676
Query: 696 SNAESRIAFVTSVHKLVSCRYEAVFYSALAVVLMAWIL--------------FENASHHS 741
E I + +VH +++ ++F + + + N ++
Sbjct: 677 RRLELIIFNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESFSYANLKDAIANQQQNN 736
Query: 742 SKVKES-SLSENNTEEHITIGSDERYLQLSDVRIPLVFMVLFNVAFFGTGNFASIASFEI 800
++ES + S NN EH+ R + ++ ++FFGTG++ +F+
Sbjct: 737 QGLEESRNESPNNPLEHVR----------QSYRYAALILLYLYISFFGTGHWFFNFTFKP 786
Query: 801 SSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKLVRVPRLGCYFLVILFSDIMT 860
+ F F ++ A ++ K+FIP ++V+ + A+ R + + L +D M+
Sbjct: 787 MTSRLFFPQFHLHMLVAFILLKIFIPSIIVMSSIYALVSFGRKNVRSIFICLFLMNDAMS 846
Query: 861 IHFFFLVKNTGSWMEIGNSISHFGIVSAQVVFVLLLFALTNLYTRS 906
++F + V N GS ++ S+ + ++ +L+ + + +
Sbjct: 847 LYFCYFVINRGSLEKVRESLDRLLVSHVFIILLLVCSWIAKGFLAN 892
>dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N short form [Mus
musculus]
Length = 798
Score = 752 bits (1922), Expect = 0.0
Identities = 257/694 (37%), Positives = 384/694 (55%), Gaps = 46/694 (6%)
Query: 45 WLVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKFFE 104
LG+ +H V+ +SIFDIYF +P+VHGM P PPAKRLVL ++DGLRAD +E
Sbjct: 3 LFFALGLLIHFVFFVSIFDIYFTSPLVHGMTPQFTPL-PPPAKRLVLFVADGLRADTLYE 61
Query: 105 PDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPV 164
DE+G RAPF+RN+I ++G WGVSH R PTESRPGHVA+IAGFYED SAV KGWK NPV
Sbjct: 62 LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121
Query: 165 EFDSVFNQSRHTFAFGSPDIIPIFCSALP--HSTWNSYPHEYEDF-ATDASFLDEWSFDQ 221
EFDS+FN+S++T+++GSPDI+P+F H SY + EDF A DA+ LD W FD+
Sbjct: 122 EFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWVFDK 181
Query: 222 FEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERV 281
+ + + + L ++++K+V FLHLLG D+NGHAHRP S Y +N+K VD + +
Sbjct: 182 VKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIKKVDDGVKEI 241
Query: 282 YHLLEDYYRDN-RTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSH 340
+ + +Y D+ +T++IFT+DHGM+D GSHG GHP+ T TP V WGAGI++P+ S +
Sbjct: 242 VSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQY 301
Query: 341 SDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGY 400
D +W L +R DVNQADIAPLM++L+G+P P+NSVG LP+GY
Sbjct: 302 DDEFL-------------KEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGY 348
Query: 401 MKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNS--LFFKPFKPLVHHSFS--LSQIDEL 456
+ + E++ N QIL Q K K + F PFK L L +
Sbjct: 349 LNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSY 408
Query: 457 ISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSS 516
I + ++ + L +L +L+L GL Y+ TYD L L + +G+ GWM +L +++ +S+
Sbjct: 409 IKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSN 468
Query: 517 LSG---DLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRL 573
+ KK H + S +++ +++ P Y+ Y + V +W + E+ +
Sbjct: 469 IPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEV 528
Query: 574 IRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFLIAGVVASILLHF 633
I+ L + L +F+ L + +E+LV SF R + L AG++ F
Sbjct: 529 IQDLVESLLTFPRSHFVAYLLVFTLG---IEVLVLSFFYR-----YMLTAGLIVFAGWPF 580
Query: 634 -SIPWRSGIPVFVCISCW--FLSVFTLMPAEIPDNNNLVSPFLGANDTDIFGWCVICDGV 690
+ W F+ + + L+VF LMP N +S +GA + + +
Sbjct: 581 LTQLWTRAKITFLSWAFFSLLLAVFPLMPVVGRKPN--LSLVMGAGFLVLLLSLAVVTTL 638
Query: 691 FV--------DKASNAESRIAFVTSVHKLVSCRY 716
+ ++ V S++ + S +
Sbjct: 639 GKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHH 672
Score = 173 bits (436), Expect = 1e-41
Identities = 44/346 (12%), Positives = 86/346 (24%), Gaps = 126/346 (36%)
Query: 502 WMIVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTV 561
W + + V
Sbjct: 506 WTYYVYCLL-------------------------------------------------PV 516
Query: 562 FLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFL 621
+W + E+ +I+ L + L +F+ L + +E+LV SF R + L
Sbjct: 517 PIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLG---IEVLVLSFFYR-----YML 568
Query: 622 IAGVVASILLHF-SIPWRSGIPVFVCISCW--FLSVFTLMPAEIPDNNNLVSPFLGANDT 678
AG++ F + W F+ + + L+VF LMP N +S +GA
Sbjct: 569 TAGLIVFAGWPFLTQLWTRAKITFLSWAFFSLLLAVFPLMPVVGRKPN--LSLVMGAGFL 626
Query: 679 DIFGWCVICDGVFV--------DKASNAESRIAFVTSVHKLVSCRY-------------- 716
+ + + + ++ V S++ + S +
Sbjct: 627 VLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQI 686
Query: 717 ----------------------------EAVF--------------YSALAVVLMAWILF 734
++ L+ ++ WI
Sbjct: 687 VSWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQV 746
Query: 735 ENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMV 780
E + V + T + R L D+R
Sbjct: 747 EQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLFF 792
>gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melanogaster]
Length = 874
Score = 751 bits (1920), Expect = 0.0
Identities = 249/927 (26%), Positives = 412/927 (43%), Gaps = 152/927 (16%)
Query: 50 GVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFS---EPPAKRLVLLISDGLRADKFFEPD 106
+ +H + + SIF IYF++P++ G+ P EPPA RLVL+++DG RAD FFE +
Sbjct: 6 ALVVHVLLLGSIFVIYFRSPVITGLTPQKHLLYYGLEPPANRLVLIVTDGFRADSFFEEN 65
Query: 107 EEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPVEF 166
P LR I +G GVS R PTE+RPGH+ +IAG YEDPSAV +GWK+NP++F
Sbjct: 66 C---RYVPNLRKIFLREGVVGVSRTRVPTETRPGHITLIAGLYEDPSAVLRGWKSNPIDF 122
Query: 167 DSVFNQSRHTFAFGSPDIIPIFCSALPHSTWNS-YPHEYEDFAT--DASFLDEWSFDQFE 223
D+VFN+S T+A+G+ D++ +F N + + DF+ DA DEW F + +
Sbjct: 123 DTVFNRSSQTYAWGANDVLNVFSHVSNGGEINLRFYNHDLDFSPGYDAYEEDEWVFKRVK 182
Query: 224 GLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYH 283
LL K + L +V FLHLLG D+ GH H+P + + ++ +K +Y
Sbjct: 183 LLLQ-----QKREALQRAQNVVFFLHLLGLDTAGHVHKPGAPKFRRTLEKTEKGVYAIYQ 237
Query: 284 LLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDS 343
E + D RT+Y+ TADHGM+D G A PKP
Sbjct: 238 EFERVFPDKRTAYLLTADHGMTDSG------------------ASRAVPKPGGR------ 273
Query: 344 VTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGYMKL 403
T + MP + QA + PLMS LLGL P+N+ G LPLGY+ +
Sbjct: 274 -TFMPNNEGPAMPLHE-----------LEQAQLTPLMSALLGLAPPMNNFGKLPLGYLNV 321
Query: 404 NEAEEVEAVVANTKQILNQL--LRKSYIKSSNSLFFKPFKPLVHHSFSLSQ--IDELISA 459
++ E A N Q+L Q L+K + K + + L + + I +L
Sbjct: 322 SKEYEAMAAHVNALQLLEQYVALQKQHKKGFFADILLEYDVLNAEAIKRYKDTIVQLQKK 381
Query: 460 KSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSSLSG 519
+ Y + + + + +LEG+ Y+ Y +L+ T + GWM + + + +S
Sbjct: 382 REYSLCIDKSQVIMSQALEGIDYYHGYYRRVLLLSTTSTFLGWMFYIYRLLSRNRASKVE 441
Query: 520 DLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRLIRGLWK 579
+ ++ + V +S + +L + L + +P Y+ + F+W + +
Sbjct: 442 LVLERSNKIVRVSIVSSVIVLIICLLSQGTPLDISFYLLLPYFVWLKALQPWN-----IN 496
Query: 580 YLRERRADYFIKLLFAAAVAVVIV----ELLVHSFTERKLYTWFFLIAGVVASILLHFSI 635
+ + Y + L + +V++ EL+V +F ER+L F + S +
Sbjct: 497 FSSSPASAYSVPALQTSMWQLVLLIACAELMVFTFFERRLIALCFCVFACYNSWE---NF 553
Query: 636 PWRSGIPVFVCISCWFLSVFTLMPAEIPDNNNLVSPFLGANDTDIF-------------- 681
W+S LS F L+P + N + LGA IF
Sbjct: 554 QWKSRDFFSWLALVLILSCFPLLPLSVGYQNGYL---LGAGVIVIFTNSFWNSKSRLCYR 610
Query: 682 -----------GWCVICDGV----------------------FVDKASNAESRI------ 702
++C + F + ESR+
Sbjct: 611 NHTKYSNALILLQTILCAYLHSNGINIPIPLKLASWLYLVYAFASILLSKESRLDLRLAQ 670
Query: 703 --AFVTSVHKLVSCRYEAVFYSALAVVLMAWILFENASHHSSKVKESSLSENNTEEHITI 760
+ S++ + YEAVF L + L +I++
Sbjct: 671 IGFNLGSLYATLCTSYEAVFVQLLTIEL----------------------------NISL 702
Query: 761 GSDERYLQLSDVRIPLVFMVLFNVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLI 820
+ + S +R+ ++ + FG+GN ASI+SF+ + +++ F+PF++ L++
Sbjct: 703 RAQSARAERSVLRLAFTLLLYTFFSLFGSGNIASISSFDPNIARCYLSHFAPFVIMGLVL 762
Query: 821 FKLFIPFMLVICAFSAITKLVRVPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNSI 880
KL +P +L++ A ++ VR + ++L D+M ++F FLV+N GSW++IG SI
Sbjct: 763 LKLLVPVVLIMSVIYANSEFVRQHEEQIFICLLLICDVMGLNFLFLVRNQGSWLDIGTSI 822
Query: 881 SHFGIVSAQVVFVLLLFALTNLYTRSI 907
SHF I+ + +L++F R I
Sbjct: 823 SHFVIMEVTTLVMLVIFYTAKQLLRVI 849
>gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinositol glycan, class N [Mus
musculus]
Length = 826
Score = 746 bits (1907), Expect = 0.0
Identities = 257/694 (37%), Positives = 383/694 (55%), Gaps = 46/694 (6%)
Query: 45 WLVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKFFE 104
LG+ +H V+ SIFDIYF +P+VHGM P PPAKRLVL ++DGLRAD +E
Sbjct: 3 LFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPL-PPPAKRLVLFVADGLRADTLYE 61
Query: 105 PDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPV 164
DE+G RAPF+RN+I ++G WGVSH R PTESRPGHVA+IAGFYED SAV KGWK NPV
Sbjct: 62 LDEDGNSRAPFIRNVIIHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121
Query: 165 EFDSVFNQSRHTFAFGSPDIIPIFCSALP--HSTWNSYPHEYEDF-ATDASFLDEWSFDQ 221
EFDS+FN+S++T+++GSPDI+P+F H SY + EDF A DA+ LD W FD+
Sbjct: 122 EFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWVFDK 181
Query: 222 FEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERV 281
+ + + + L ++++K+V FLHLLG D+NGHAHRP S Y +N+K VD + +
Sbjct: 182 VKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEI 241
Query: 282 YHLLEDYYRDN-RTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSH 340
+ + +Y D+ +T++IFT+DHGM+D GSHG GHP+ T TP V WGAGI++P+ S +
Sbjct: 242 VSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQY 301
Query: 341 SDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGY 400
D +W L +R DVNQADIAPLM++L+G+P P+NSVG LP+GY
Sbjct: 302 DDEFL-------------KEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGY 348
Query: 401 MKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNS--LFFKPFKPLVHHSFS--LSQIDEL 456
+ + E++ N QIL Q K K + F PFK L L +
Sbjct: 349 LNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSY 408
Query: 457 ISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSS 516
I + ++ + L +L +L+L GL Y+ TYD L L + +G+ GWM +L +++ +S+
Sbjct: 409 IKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSN 468
Query: 517 LSG---DLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRL 573
+ KK H + S +++ +++ P Y+ Y + V +W + E+ +
Sbjct: 469 IPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEV 528
Query: 574 IRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFLIAGVVASILLHF 633
I+ L + L +F+ L + +E+LV SF R + L AG++ F
Sbjct: 529 IQDLVESLLTFPRSHFVAYLLVFTLG---IEVLVLSFFYR-----YMLTAGLIVFAGWPF 580
Query: 634 -SIPWRSGIPVFVCISCW--FLSVFTLMPAEIPDNNNLVSPFLGANDTDIFGWCVICDGV 690
+ W F+ + + L+VF LMP N +S +GA + + +
Sbjct: 581 LTQLWTRAKITFLSWAFFSLLLAVFPLMPVVGRKPN--LSLVMGAGFLVLLLSLAVVTTL 638
Query: 691 FV--------DKASNAESRIAFVTSVHKLVSCRY 716
+ ++ V S++ + S +
Sbjct: 639 GKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHH 672
Score = 170 bits (427), Expect = 1e-40
Identities = 47/352 (13%), Positives = 91/352 (25%), Gaps = 126/352 (35%)
Query: 502 WMIVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTV 561
W + + V
Sbjct: 506 WTYYVYCLL-------------------------------------------------PV 516
Query: 562 FLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFL 621
+W + E+ +I+ L + L +F+ L + +E+LV SF R + L
Sbjct: 517 PIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLG---IEVLVLSFFYR-----YML 568
Query: 622 IAGVVASILLHF-SIPWRSGIPVFVCISCW--FLSVFTLMPAEIPDNNNLVSPFLGANDT 678
AG++ F + W F+ + + L+VF LMP N +S +GA
Sbjct: 569 TAGLIVFAGWPFLTQLWTRAKITFLSWAFFSLLLAVFPLMPVVGRKPN--LSLVMGAGFL 626
Query: 679 DIFGWCVICDGVFV--------DKASNAESRIAFVTSVHKLVSCRY-------------- 716
+ + + + ++ V S++ + S +
Sbjct: 627 VLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQI 686
Query: 717 ----------------------------EAVF--YSA------------LAVVLMAWILF 734
++ Y L+ ++ WI
Sbjct: 687 VSWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQV 746
Query: 735 ENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMVLFNVAF 786
E + V + T + R L D+R ++L F
Sbjct: 747 EQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLILLIFPVF 798
>ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class N [Mus musculus]
dbj|BAA82619.1| (AB030279) phosphatidylinositolglycan class N [Mus musculus]
Length = 931
Score = 738 bits (1885), Expect = 0.0
Identities = 257/694 (37%), Positives = 384/694 (55%), Gaps = 46/694 (6%)
Query: 45 WLVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKFFE 104
LG+ +H V+ +SIFDIYF +P+VHGM P PPAKRLVL ++DGLRAD +E
Sbjct: 3 LFFALGLLIHFVFFVSIFDIYFTSPLVHGMTPQFTPL-PPPAKRLVLFVADGLRADTLYE 61
Query: 105 PDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPV 164
DE+G RAPF+RN+I ++G WGVSH R PTESRPGHVA+IAGFYED SAV KGWK NPV
Sbjct: 62 LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121
Query: 165 EFDSVFNQSRHTFAFGSPDIIPIFCSALP--HSTWNSYPHEYEDF-ATDASFLDEWSFDQ 221
EFDS+FN+S++T+++GSPDI+P+F H SY + EDF A DA+ LD W FD+
Sbjct: 122 EFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWVFDK 181
Query: 222 FEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERV 281
+ + + + L ++++K+V FLHLLG D+NGHAHRP S Y +N+K VD + +
Sbjct: 182 VKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIKKVDDGVKEI 241
Query: 282 YHLLEDYYRDN-RTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSH 340
+ + +Y D+ +T++IFT+DHGM+D GSHG GHP+ T TP V WGAGI++P+ S +
Sbjct: 242 VSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQY 301
Query: 341 SDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGY 400
D +W L +R DVNQADIAPLM++L+G+P P+NSVG LP+GY
Sbjct: 302 DDEFL-------------KEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGY 348
Query: 401 MKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNS--LFFKPFKPLVHHSFS--LSQIDEL 456
+ + E++ N QIL Q K K + F PFK L L +
Sbjct: 349 LNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSY 408
Query: 457 ISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSS 516
I + ++ + L +L +L+L GL Y+ TYD L L + +G+ GWM +L +++ +S+
Sbjct: 409 IKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSN 468
Query: 517 LSG---DLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRL 573
+ KK H + S +++ +++ P Y+ Y + V +W + E+ +
Sbjct: 469 IPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEV 528
Query: 574 IRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFLIAGVVASILLHF 633
I+ L + L +F+ L + +E+LV SF R + L AG++ F
Sbjct: 529 IQDLVESLLTFPRSHFVAYLLVFTLG---IEVLVLSFFYR-----YMLTAGLIVFAGWPF 580
Query: 634 -SIPWRSGIPVFVCISCW--FLSVFTLMPAEIPDNNNLVSPFLGANDTDIFGWCVICDGV 690
+ W F+ + + L+VF LMP N +S +GA + + +
Sbjct: 581 LTQLWTRAKITFLSWAFFSLLLAVFPLMPVVGRKPN--LSLVMGAGFLVLLLSLAVVTTL 638
Query: 691 FV--------DKASNAESRIAFVTSVHKLVSCRY 716
+ ++ V S++ + S +
Sbjct: 639 GKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHH 672
Score = 367 bits (934), Expect = e-100
Identities = 108/470 (22%), Positives = 180/470 (37%), Gaps = 126/470 (26%)
Query: 502 WMIVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTV 561
W + + V
Sbjct: 506 WTYYVYCLL-------------------------------------------------PV 516
Query: 562 FLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFL 621
+W + E+ +I+ L + L +F+ L + +E+LV SF R + L
Sbjct: 517 PIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLG---IEVLVLSFFYR-----YML 568
Query: 622 IAGVVASILLHF-SIPWRSGIPVFVCISCW--FLSVFTLMPAEIPDNNNLVSPFLGANDT 678
AG++ F + W F+ + + L+VF LMP N +S +GA
Sbjct: 569 TAGLIVFAGWPFLTQLWTRAKITFLSWAFFSLLLAVFPLMPVVGRKPN--LSLVMGAGFL 626
Query: 679 DIFGWCVICDGVFV--------DKASNAESRIAFVTSVHKLVSCRY-------------- 716
+ + + + ++ V S++ + S +
Sbjct: 627 VLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQI 686
Query: 717 ----------------------------EAVF--YSA------------LAVVLMAWILF 734
++ Y L+ ++ WI
Sbjct: 687 VSWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQV 746
Query: 735 ENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMVLFNVAFFGTGNFAS 794
E + V + T + R L D+R + AFFGTGN AS
Sbjct: 747 EQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLVFFLLTAFFGTGNIAS 806
Query: 795 IASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKLVRVPRLGCYFLVIL 854
I SF+++SVY F+T+FSPF+M AL+++K+ IPF+LV+CAF A+ ++ G + +V++
Sbjct: 807 INSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQITTQLSSKGLFLVVLI 866
Query: 855 FSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVSAQVVFVLLLFALTNLYT 904
SDIM +HFFFLVK++GSW++IG SISH+ IV + +F++ L L L T
Sbjct: 867 ISDIMALHFFFLVKDSGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLT 916
>ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class N; endoplasmic
reticulum membrane protein [Homo sapiens]
gb|AAD11432.1| (AF109219) Mcd4p homolog [Homo sapiens]
Length = 931
Score = 737 bits (1883), Expect = 0.0
Identities = 254/692 (36%), Positives = 381/692 (54%), Gaps = 46/692 (6%)
Query: 45 WLVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKFFE 104
LG+ +H V+ SIFDIYF +P+VHGM P PPA+RLVL ++DGLRAD +E
Sbjct: 3 LFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPL-PPPARRLVLFVADGLRADALYE 61
Query: 105 PDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPV 164
DE G RAPF+RNII ++G WG+SH R PTESRPGHVA+IAGFYED SAV KGWK NPV
Sbjct: 62 LDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121
Query: 165 EFDSVFNQSRHTFAFGSPDIIPIFCSALP--HSTWNSYPHEYEDF-ATDASFLDEWSFDQ 221
EFDS+FN+S++T+++GSPDI+P+F H SY + EDF A DA+ LD W FD
Sbjct: 122 EFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDFGAQDATKLDTWVFDN 181
Query: 222 FEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERV 281
+ + + + L ++++K+V FLHLLG D+NGHAHRP S Y +N+K VD + +
Sbjct: 182 VKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDDGVKEI 241
Query: 282 YHLLEDYY-RDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSH 340
+ +Y D +T++IFT+DHGM+D GSHG GHP+ T TPLV WGAGI+YP+ S
Sbjct: 242 VSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSAQQF 301
Query: 341 SDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGY 400
D+ +W L +R+DVNQADIAPLM++L+G+P P+NSVG LP+ Y
Sbjct: 302 DDAFL-------------KEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILPVDY 348
Query: 401 MKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNS--LFFKPFKPLVHHSFS--LSQIDEL 456
+ + + E++ N QIL Q K K + F PFK L L +
Sbjct: 349 LNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILRKARSY 408
Query: 457 ISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSS 516
I + ++ + L +L +L+L+GL Y+ TYD L + +G+ GW+ +L +++ +S+
Sbjct: 409 IKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLIIKSHSN 468
Query: 517 LSG---DLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRL 573
L KK + S + +++ L++ P Y+ Y + + +W + E+++
Sbjct: 469 LIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWYAVLREFQV 528
Query: 574 IRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFLIAGVVASILLHF 633
I+ L + +F+ L A + +E+LV SF R + L AG+ A F
Sbjct: 529 IQDLVVSVLTYPLSHFVGYLLAFTLG---IEVLVLSFFYR-----YMLTAGLTAFAAWPF 580
Query: 634 -SIPWRSGIPVFVCISCW--FLSVFTLMPAEIPDNNNLVSPFLGANDTDIFGWCVICDGV 690
+ W + + + L+VF LMP + +S +GA + + +
Sbjct: 581 LTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPD--ISLVMGAGLLVLLLSLCVVTSL 638
Query: 691 FV--------DKASNAESRIAFVTSVHKLVSC 714
+ + ++ V S++ + S
Sbjct: 639 MKRKDSFIKEELLVHLLQVLSTVLSMYVVYST 670
Score = 367 bits (934), Expect = e-100
Identities = 108/470 (22%), Positives = 181/470 (37%), Gaps = 126/470 (26%)
Query: 502 WMIVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTV 561
W + + +
Sbjct: 506 WTYYVY-------------------------------------------------GLLPL 516
Query: 562 FLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFL 621
+W + E+++I+ L + +F+ L A + +E+LV SF R + L
Sbjct: 517 PIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLG---IEVLVLSFFYR-----YML 568
Query: 622 IAGVVASILLHF-SIPWRSGIPVFVCISCW--FLSVFTLMPAEIPDNNNLVSPFLGANDT 678
AG+ A F + W + + + L+VF LMP + +S +GA
Sbjct: 569 TAGLTAFAAWPFLTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPD--ISLVMGAGLL 626
Query: 679 DIFGWCVICDGVFV--------DKASNAESRIAFVTSVHKLVSC---------------- 714
+ + + + + ++ V S++ + S
Sbjct: 627 VLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQI 686
Query: 715 ---------------RYEAVF-------------YSAL------------AVVLMAWILF 734
+F Y L + ++ WI
Sbjct: 687 ISWATLASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINI 746
Query: 735 ENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMVLFNVAFFGTGNFAS 794
E + S V + + T + R L L D+R + AFFGTGN AS
Sbjct: 747 EQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIAS 806
Query: 795 IASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKLVRVPRLGCYFLVIL 854
I SF+++SVY F+T+FSPF+M AL+++K+ IPF+LV+CAF A+ ++ + +V++
Sbjct: 807 INSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLV 866
Query: 855 FSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVSAQVVFVLLLFALTNLYT 904
SDIM +HFFFLVK+ GSW++IG SISH+ IV + +F++ L L L T
Sbjct: 867 ISDIMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLT 916
>gb|AAF54657.1| (AE003692) CG6790 gene product [Drosophila melanogaster]
gb|AAL28155.1| (AY060607) GH02677p [Drosophila melanogaster]
Length = 858
Score = 719 bits (1838), Expect = 0.0
Identities = 173/905 (19%), Positives = 348/905 (38%), Gaps = 134/905 (14%)
Query: 51 VALHAVYMLSIFDIYFKTPIVHGMDPVPPRFS---EPPAKRLVLLISDGLRADKFFEPDE 107
V +H + ++ I I++++ + ++P P A RLV+ + +GLRAD F +
Sbjct: 9 VLVHLLLLICIMRIFYQSGPLSQLEPQKTLLDMGVPPAADRLVVFLLEGLRADTLFSDNC 68
Query: 108 EGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFD 167
G A ++R+II QG G+S PT +R VA+ AGF PS + FD
Sbjct: 69 SG---AVYIRDIILRQGLVGISKTSVPTLTRSAEVALFAGFNPMPSILPT------SNFD 119
Query: 168 SVFNQSRHTFAFGSPDIIPIFCSALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLN 227
++FN++ F + F+ L
Sbjct: 120 TIFNRTL------------AFDKGA-----------FLRFS------------HLSDLRR 144
Query: 228 RSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLED 287
R L++L + +KLV+ ++L P + + + Y L+E
Sbjct: 145 RLTKRACLEKLWYANKLVMLVNLAEV----GGASPLDIGFQMKLHNTQRNIRDAYELIEA 200
Query: 288 YYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTF 347
+ D++T+Y++T+ HG++ GSHG G + P + WGAG++ + N SD F
Sbjct: 201 TFNDSKTAYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGVK---HVTENITSD----F 253
Query: 348 VDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGYMKLNEAE 407
V + M ++Q +APLMS L+GLP PVN++ LP GYMK++
Sbjct: 254 VLNNGVGMQLHK-----------LDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSREY 302
Query: 408 EVEAVVANTKQILNQLLRKSYIKSSNSLFFKPFKP------LVHHSFSLSQIDELISAKS 461
++V N Q+L Q K+ I+ F + P L ++ +Q+D L+
Sbjct: 303 ARKSVHLNALQLLTQA--KAIIRLHERGVFHKWLPKDKDLDLQQIAYYQNQMDHLLDMGW 360
Query: 462 YEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSSLSGDL 521
A++ + ++L+ L ++ Y + L+ L GW + + Q +
Sbjct: 361 RSKALETSTLAIKVALKSLKFYHNYYHIPLVVTTVLALLGWQFYQLVKLSQNVMAPHYM- 419
Query: 522 SKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRLIRGLWKYL 581
+ I L +L + ++ +P + + + +W + G W +
Sbjct: 420 RRGYLTWCTIFLASLGLLLGEMVFLQWAPFMTVICLVVPFGVWCMTLAALP-QNGGWIFE 478
Query: 582 RERRADYFIKL---LFAAA---VAVVIVELLVHSFTERKLYTWFFLIAGVVASILLHFSI 635
+ + + + A+ + + +L F R+ + +++L
Sbjct: 479 PLKHLRWIVGPAAVMIASIYCNCPLSLAYILCVGFYNRRGWLHPSPKFLAWLALVLLLGG 538
Query: 636 PWRSGIPVFVCISC---WFLSVFTLMPAEIP-----DNNNLVSPFLGANDTD-----IFG 682
S + + ++ L +++ + +N+ + IF
Sbjct: 539 FLWSQKGMQILMTTNYRVVLQAISMLVVIVRPCVLNENHKWKVWVINGGILFVAAIGIFL 598
Query: 683 WCV---ICDGVFV---------------DKAS----NAESRIAFVTSVHKLVSCRYEAVF 720
+ + +F + E + ++H L+S Y ++F
Sbjct: 599 KEMGKPVPLYLFAANWAYLIYAFASVPCSSRTTPQSRLELIRFNLLTLHVLLSDSYVSLF 658
Query: 721 YSALAVVLMAWILFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMV 780
I ++ K KE+ E + I + ++LQ+ R + ++
Sbjct: 659 ------AQGLIIEYQMGLEVHEKFKEAD-------EDVKILTSSKHLQMC-YRFAVSILL 704
Query: 781 LFNVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKL 840
F + FGTG++ ++ +S F+ S L+ L++ L IP ++++ + A++
Sbjct: 705 YFYASLFGTGHWVGGFTYLANSARLFLPDSSSGLVPLLVLIHLLIPSIVIMASVVALSSF 764
Query: 841 VRVPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVSAQVVFVLLLFALT 900
R + ++L + + + F V + W S+ H + V+ +L ++
Sbjct: 765 GRQQIRTIFSSLMLICNAVVLFFVVFVPHNAYWPMAHPSVVHALLAQLTVILILACESIV 824
Query: 901 NLYTR 905
++ R
Sbjct: 825 TIFFR 829
>ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; Mcd4p [Saccharomyces
cerevisiae]
sp|P36051|YKQ5_YEAST HYPOTHETICAL 105.7 KD PROTEIN IN TPK3-PIR1 INTERGENIC REGION
pir||S37786 hypothetical protein YKL165c - yeast (Saccharomyces cerevisiae)
emb|CAA81489.1| (Z26877) unknown [Saccharomyces cerevisiae]
emb|CAA82007.1| (Z28165) ORF YKL165c [Saccharomyces cerevisiae]
prf||2118404A ORF [Saccharomyces cerevisiae]
Length = 919
Score = 621 bits (1586), Expect = e-176
Identities = 252/664 (37%), Positives = 359/664 (53%), Gaps = 47/664 (7%)
Query: 38 WLKRRETWLVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGL 97
W K R T L V GV H Y+ SIFDIYF +P+VHGM P PPAKRL L++ DGL
Sbjct: 2 WNKTRTTLLAV-GVLFHLFYLWSIFDIYFISPLVHGMSPYQST-PTPPAKRLFLIVGDGL 59
Query: 98 RADKFF-----EPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDP 152
RAD F + ++ APF+R+++ N +G+SH R PTESRPGHVA+IAGFYED
Sbjct: 60 RADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDV 119
Query: 153 SAVTKGWKANPVEFDSVFNQSRHTFAFGSPDIIPIFCSALPH----STWNSYPHEYEDFA 208
SAVTKGWK+NPV FDS FNQS HT++FGSPDI+P+F TW Y H +EDF
Sbjct: 120 SAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTW-MYDHTFEDFT 178
Query: 209 TDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYL 268
+ LD + F + L + S + L + QD V FLHLLGCD+ GH++RPYS+ Y
Sbjct: 179 QSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYY 238
Query: 269 NNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAG 328
+NVK +D + + ++ D++T++IFTADHGMS GSHGDGHP NT TPLVAWGAG
Sbjct: 239 DNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAG 298
Query: 329 IQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPC 388
+ P +W L ++R DV QADIA LMS L+G+
Sbjct: 299 LNKPVHNP--------------FPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNY 344
Query: 389 PVNSVGNLPLGYMKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNSLFFKPFKPLV--HH 446
P NSVG LP+ Y+ E++++ A+ N + IL Q L K + F+K + V H
Sbjct: 345 PKNSVGELPIAYIDGKESDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSH 404
Query: 447 SFSLSQIDELISAKS------YEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYT 500
S L +I+ LI S + A+ L +L ++LEGLHY TY+W + T++T G+
Sbjct: 405 SHYLEEIETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFV 464
Query: 501 GWMIVLALHVLQCYSSLS-GDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGM 559
GW+ + L+ + + D K LS + G + +L+ + +HSP ++ Y+
Sbjct: 465 GWIFFSFIIFLKSFILENVIDDQKASPLSHAVFG-SIGILLNWILFYQHSPFNFYMYLLF 523
Query: 560 TVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWF 619
++ W+ IF+ ++R K + + + K + + + E +V+ F R +T
Sbjct: 524 PLYFWSYIFTNRSVLRSGIKEFFKGTSPW--KRVLITISIISVYEGIVYGFFHRWTFT-- 579
Query: 620 FLIAGVVASILLHFSIPWRSGIPVFVCISCWFLSVFTLMP-AEIPDNNNLVSPFLGANDT 678
LI ++A + S + + I+ LS FTL +I D N + A
Sbjct: 580 -LITNILAFYPFICGVRELS-VNILWIITSVLLSTFTLFDAVKIEDLNQIHL----AGLL 633
Query: 679 DIFG 682
I
Sbjct: 634 IILS 637
Score = 245 bits (620), Expect = 3e-63
Identities = 91/422 (21%), Positives = 168/422 (39%), Gaps = 39/422 (9%)
Query: 499 YTGWMIVLALHVLQCYSSL---SGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHA 555
Y + + ++ S L + K + +S++++ E +Y
Sbjct: 520 YLLFPLYFWSYIFTNRSVLRSGIKEFFKGTSPWKRVL-----ITISIISVYEGI--VYGF 572
Query: 556 YIGMTVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKL 615
+ T L T I + Y I G + L +L + V++ + L
Sbjct: 573 FHRWTFTLITNILAFYPFICG-VRELSVNILWIITSVLLSTFTLFDAVKIEDLNQIH--L 629
Query: 616 YTWFFLIAGVVASILLHFSI-PWRSGIPVFVCISCWFLSVFTLMPAEIPDNNNLV---SP 671
+++ A +H I + I + T + S
Sbjct: 630 AGLLIILSAFYALYKIHSRINSYTRAIFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQ 689
Query: 672 FLGANDTDIFGWCVICDGVFVDKA---SNAESRIAFVTSVHKLVSCRYEAVFYSALAVVL 728
G + + + +++ +E++FY +
Sbjct: 690 VAGWIIFFVSLFVMPILHYRKPNNDYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYM 749
Query: 729 MAWILFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMVLFNVAFFG 788
+ WI EN K+KE + DE +LQ+ +R+ ++ L VAFFG
Sbjct: 750 VQWIEIEN------KIKEMKTQK-----------DENWLQV--LRVSVIGFFLLQVAFFG 790
Query: 789 TGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKLVRVPRLGC 848
TGN ASI+SF + SV R + IF PFLM ALL+ KL IP+ L+ + +
Sbjct: 791 TGNVASISSFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTI 850
Query: 849 YFLVILFSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVSAQVVFVLLLFALTNLYTRSIR 908
L+I SDI++++FF+L++ GSW++IG +IS++ + +F+L+L L ++ +++
Sbjct: 851 SSLIISMSDILSLNFFYLLRTEGSWLDIGITISNYCLAILSSLFMLILEVLGHVLLKNVI 910
Query: 909 IK 910
I+
Sbjct: 911 IQ 912
>gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caenorhabditis elegans]
Length = 929
Score = 600 bits (1533), Expect = e-170
Identities = 203/653 (31%), Positives = 328/653 (50%), Gaps = 65/653 (9%)
Query: 44 TW-LVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKF 102
+W ++ + +H V + SIFD+Y+ +P+VHG+ P E PAKR+ ++ +DGLR D F
Sbjct: 2 SWKFLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDTF 61
Query: 103 FEPDEEGKYRAPFLRNIIK-NQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKA 161
+ ++ P+L +I+ +G +G+S + PTESRPGHVAI AG ED SAV KGWK
Sbjct: 62 NKYPDKS----PYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKK 117
Query: 162 NPVEFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTWNSYPHEYEDFAT-DASFLDEWSFD 220
NPV+FDSVFN+S +++ +GSPDI+ +F LP++ SY + EDFA+ DAS LD+W F+
Sbjct: 118 NPVQFDSVFNRSSYSWMWGSPDIVNLFDD-LPNAESFSYSADEEDFASKDASNLDKWVFE 176
Query: 221 QFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAER 280
FE L + D L + + + K + FLHLLG D+NGH ++P S Y++N+KVVD E+
Sbjct: 177 HFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEK 236
Query: 281 VYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSH 340
V HL++ ++ D++T+++FT+DHGM+D GSHG G TP VAWGAG++ P
Sbjct: 237 VQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGGP------ 290
Query: 341 SDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGY 400
++D+NQ D+APL+S L+G P PVNS+G LP+
Sbjct: 291 ---------------------------KLDLNQIDLAPLISALIGCPIPVNSMGILPVQM 323
Query: 401 MKLN-EAEEVEAVVANTKQILNQ-LLRKSYIKSSNSLFFKPFKPLVHHSFS--LSQIDEL 456
M + E +A+ AN KQ+ Q + K+ S L+F+ F+ + + + +L
Sbjct: 324 MNSKGSSYEFKAIEANFKQLKEQIIFLKNA--KSRRLWFRQFEKFGDKAMESLRTTLAQL 381
Query: 457 ISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSS 516
+ + A L D +L E + ++ YD ML ++ + W+ ++ + S
Sbjct: 382 GRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIALVVSFLHNSTSK 441
Query: 517 LSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRLIRG 576
+ L HL + C L+ + + + +++ ++ IR
Sbjct: 442 ENLSLLVPHHLFIIPLACSLLFTAYCSLSMTQTIYIILPIYLISILENHSKLTQR--IRE 499
Query: 577 LWKYLRERR--------ADYFIKLLFAAAVAVVIVELLVHSFTERK-LYTWFFLIAGVVA 627
K L + + F+K + + + V +F +R L F L+ +
Sbjct: 500 HVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAVFVLLMALPQ 559
Query: 628 SILLHFSIPWRSGIPVFVCISCWFLSVFTLMPAEIPDNN---NLVSPFLGAND 677
W C L +F +PA + ++SP + A
Sbjct: 560 FYSHPIVSYWSKT----WLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFL 608
Score = 210 bits (530), Expect = 1e-52
Identities = 85/401 (21%), Positives = 144/401 (35%), Gaps = 56/401 (13%)
Query: 513 CYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYR 572
K V G + + VL ++ + + M + + +
Sbjct: 512 NKVLSVEVFVKPFLGFV---GFSITICIFVLTFMDRAFLAAVFVLLMALPQFYS----HP 564
Query: 573 LIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFLIAGVVASILLH 632
++ K I A + L + S I L
Sbjct: 565 IVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCILS-----------PIITAFLCHRLS 613
Query: 633 FSIPWRSGIPVFVCISCWFLSVFTLMPAE---IPDNNNLVSPFLGANDTDI--------- 680
+ + + ++ L+ ++
Sbjct: 614 RRSCLTRIQRMLELMIYVQSATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSLQPP 673
Query: 681 -----FGWCVICDGVFVDKAS-------NAESRIAFVTSVHKLVSCRYEAVFYSALAVVL 728
W I V + + L+S YE++F V+L
Sbjct: 674 SIARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFLVLL 733
Query: 729 MAWILFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMVLFNVAFFG 788
++ FE H S V+ L ++T S Y++L + + F++ FG
Sbjct: 734 TLFVRFEFG--HLSDVELLQLKVDST-----KISTGEYVELRRTVVCVSFVL---CPLFG 783
Query: 789 TGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKLVR--VPRL 846
TGNFASI SF S++ FI++FSPF MA LLI KL IP +LV AF++I + + + RL
Sbjct: 784 TGNFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQESIQRL 843
Query: 847 GCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVS 887
C+ L+ F+D M++ FF +++ GSW++IG SIS F +
Sbjct: 844 CCFSLI--FTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSM 882
>pir||T40715 hypothetical protein SPBC839.08c - fission yeast
(Schizosaccharomyces pombe)
emb|CAA17011.1| (AL021816) hypothetical protein [Schizosaccharomyces pombe]
emb|CAB46701.1| (AL096796) hypothetical protein [Schizosaccharomyces pombe]
Length = 935
Score = 597 bits (1525), Expect = e-169
Identities = 257/667 (38%), Positives = 366/667 (54%), Gaps = 49/667 (7%)
Query: 46 LVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKFFEP 105
L++LG+ H V++ SIFDIYF TP++HGM E PAKRL L++ DGLR DK +P
Sbjct: 5 LLLLGILFHVVFLKSIFDIYFVTPLIHGMKQYSAG--EAPAKRLFLIVGDGLRPDKLLQP 62
Query: 106 D------EEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGW 159
EE Y APFLR+II+N G +GVSH R PTESRPGHVA+IAGFYED SAVTKGW
Sbjct: 63 HSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGW 122
Query: 160 KANPVEFDSVFNQSRHTFAFGSPDIIPIFCSALPH---STWNSYPHEYEDFATDASFLDE 216
K NPV FDSVFNQSRHT++FGS DI+P+F Y E EDF+++ LDE
Sbjct: 123 KKNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVLDE 182
Query: 217 WSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDK 276
W FD+ + LL +S D +L ++LH+DK+V FLHLLG D+ GH P S Y+ N++ +D
Sbjct: 183 WVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDG 242
Query: 277 IAERVYH-LLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPA 335
+ + + Y D +S++FTADHGMSD GSHGDG+ NT TP++AWGAGIQ P
Sbjct: 243 KIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHE 302
Query: 336 SGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGN 395
H + W L ++R+D+ QADIA LMS L+GL PVNSVG
Sbjct: 303 KNYGHDEYSL--------------PWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQ 348
Query: 396 LPLGYMKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNSLFFKPFKPL-----VHHSFSL 450
+PL Y+ + + E + N +I Q KS K S+FF+P+ PL V SF
Sbjct: 349 IPLDYLDCSSRRKAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASFYN 408
Query: 451 SQIDELISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHV 510
S I + I + YE A++ L GL Y Q YDWL+L +++ GY W+ + V
Sbjct: 409 SVIAD-IESGEYEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFV 467
Query: 511 LQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAY-IGMTVFLW--TQI 567
S + K + ++ + ++ + ++ SPP Y+ Y + T+FL I
Sbjct: 468 FSLNIEPSSKIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSI 527
Query: 568 FSEYRL-IRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFLIAGVV 626
F +L + +++ +K+LF + + +++ +V+S+ R+ ++ ++ G+
Sbjct: 528 FPNTKLGFKNFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFS--VILMGLA 585
Query: 627 A-SILLHFSIPW-RSGIPVFVCISCWFLSVFTLMPAEIPDNNNLVSPFLGANDTDIFGWC 684
A LLH + I V + L FT++P N F+ A G+
Sbjct: 586 AWPWLLHADYAFSHKTISVSWSVLTSLLCFFTILPV----NKKESLLFIFAG-----GFA 636
Query: 685 VICDGVF 691
+ GVF
Sbjct: 637 MSVAGVF 643
Score = 263 bits (666), Expect = 1e-68
Identities = 90/390 (23%), Positives = 155/390 (39%), Gaps = 33/390 (8%)
Query: 535 LLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLF 594
+L L +L L++ Y G +V L + L + + +
Sbjct: 553 ILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADYAFSHKTISVSWSV---- 608
Query: 595 AAAVAVVIVELLVHSFTERKLYTWFFLIAGVVASILLHFSIPWRSGIPVFVCISC----W 650
++ +K F G S+ F I +R +
Sbjct: 609 ----LTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQYSSTVTNKQL 664
Query: 651 FLSVFTLMPAEIPDNNNLVSPFLGAN---DTDIFGWCVICDGVFVDK----------ASN 697
L V +M S + + + +
Sbjct: 665 VLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIPSHHIRSCKHYFLDR 724
Query: 698 AESRIAFVTSVHKLVSCRYEAVFYSALAVVLMAWILFENASHHSSKVKESSLSENNTEEH 757
+ ++S +EA+FY L + L W+ E + +E E+
Sbjct: 725 LAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELET--------ELQKYTEQLHPEY 776
Query: 758 ITIGSDERYLQLSDVRIPLVFMVLFNVAFFGTGNFASIASFEISSVYRFITIFSPFLMAA 817
+ +L LS +RI L F + NVAFFGTGN AS+++F + SV RFI +F+P A
Sbjct: 777 SRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQGA 836
Query: 818 LLIFKLFIPFMLVICAFSAITKLVRVPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIG 877
LL++ + +PF+ + AF + K + + +FL + +DI+TI+FF+LVK+ GSW +IG
Sbjct: 837 LLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYLVKDEGSWKDIG 896
Query: 878 NSISHFGIVSAQVVFVLLLFALTNLYTRSI 907
SISHF I + ++F+ L + + ++I
Sbjct: 897 VSISHFCISNFLILFITALEHASAILCKNI 926
>pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragment)
emb|CAB70839.1| (AL137607) hypothetical protein [Homo sapiens]
Length = 825
Score = 590 bits (1506), Expect = e-167
Identities = 191/587 (32%), Positives = 304/587 (51%), Gaps = 45/587 (7%)
Query: 150 EDPSAVTKGWKANPVEFDSVFNQSRHTFAFGSPDIIPIFCSALP--HSTWNSYPHEYEDF 207
ED SAV KGWK NPVEFDS+FN+S++T+++GSPDI+P+F H SY + EDF
Sbjct: 1 EDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDF 60
Query: 208 -ATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSI 266
A DA+ LD W FD + + + + L ++++K+V FLHLLG D+NGHAHRP S
Sbjct: 61 GAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRD 120
Query: 267 YLNNVKVVDKIAERVYHLLEDYY-RDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAW 325
Y +N+K VD + + + +Y D +T++IFT+DHGM+D GSHG GHP+ T TPLV W
Sbjct: 121 YKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTW 180
Query: 326 GAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLG 385
GAGI+YP+ S D+ +W L +R+DVNQADIAPLM++L+G
Sbjct: 181 GAGIKYPQRVSAQQFDDAFL-------------KEWRLENWKRLDVNQADIAPLMTSLIG 227
Query: 386 LPCPVNSVGNLPLGYMKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNS--LFFKPFKPL 443
+P P+NSVG LP+ Y+ + + E++ N QIL Q K K + F PFK L
Sbjct: 228 VPFPLNSVGILPVDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLL 287
Query: 444 VHHSFS--LSQIDELISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTG 501
L + I + ++ + L +L +L+L+GL Y+ TYD L + +G+ G
Sbjct: 288 SDSKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVG 347
Query: 502 WMIVLALHVLQCYSSLSG---DLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIG 558
W+ +L +++ +S+L KK + S + +++ L++ P Y+ Y
Sbjct: 348 WISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGL 407
Query: 559 MTVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTW 618
+ + +W + E+++I+ L + +F+ L A + +E+LV SF R
Sbjct: 408 LPLPIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLG---IEVLVLSFFYR----- 459
Query: 619 FFLIAGVVASILLHF-SIPWRSGIPVFVCISCW--FLSVFTLMPAEIPDNNNLVSPFLGA 675
+ L AG+ A F + W + + + L+VF LMP + +S +GA
Sbjct: 460 YMLTAGLTAFAAWPFLTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPD--ISLVMGA 517
Query: 676 NDTDIFGWCVICDGVFV--------DKASNAESRIAFVTSVHKLVSC 714
+ + + + + ++ V S++ + S
Sbjct: 518 GLLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYST 564
Score = 367 bits (934), Expect = e-100
Identities = 108/470 (22%), Positives = 181/470 (37%), Gaps = 126/470 (26%)
Query: 502 WMIVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTV 561
W + + +
Sbjct: 400 WTYYVY-------------------------------------------------GLLPL 410
Query: 562 FLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFL 621
+W + E+++I+ L + +F+ L A + +E+LV SF R + L
Sbjct: 411 PIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLG---IEVLVLSFFYR-----YML 462
Query: 622 IAGVVASILLHF-SIPWRSGIPVFVCISCW--FLSVFTLMPAEIPDNNNLVSPFLGANDT 678
AG+ A F + W + + + L+VF LMP + +S +GA
Sbjct: 463 TAGLTAFAAWPFLTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPD--ISLVMGAGLL 520
Query: 679 DIFGWCVICDGVFV--------DKASNAESRIAFVTSVHKLVSC---------------- 714
+ + + + + ++ V S++ + S
Sbjct: 521 VLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQI 580
Query: 715 ---------------RYEAVF-------------YSAL------------AVVLMAWILF 734
+F Y L + ++ WI
Sbjct: 581 ISWATLASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINI 640
Query: 735 ENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMVLFNVAFFGTGNFAS 794
E + S V + + T + R L L D+R + AFFGTGN AS
Sbjct: 641 EQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIAS 700
Query: 795 IASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKLVRVPRLGCYFLVIL 854
I SF+++SVY F+T+FSPF+M AL+++K+ IPF+LV+CAF A+ ++ + +V++
Sbjct: 701 INSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLV 760
Query: 855 FSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVSAQVVFVLLLFALTNLYT 904
SDIM +HFFFLVK+ GSW++IG SISH+ IV + +F++ L L L T
Sbjct: 761 ISDIMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLT 810
>ref|XP_082200.1| (XM_082200) CG6790 [Drosophila melanogaster]
Length = 656
Score = 555 bits (1417), Expect = e-156
Identities = 115/671 (17%), Positives = 244/671 (36%), Gaps = 91/671 (13%)
Query: 282 YHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHS 341
+ T + GSHG G + P + WGAG++ + N S
Sbjct: 1 MTRKRHTFIHQHTVLLI--------SGSHGGGSDEEREAPFLLWGAGVK---HVTENITS 49
Query: 342 DSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGYM 401
D FV + M ++Q +APLMS L+GLP PVN++ LP GYM
Sbjct: 50 D----FVLNNGVGMQLHK-----------LDQIQLAPLMSALIGLPPPVNNLAILPQGYM 94
Query: 402 KLNEAEEVEAVVANTKQILNQLLRKSYIKSSNSLFFKPFKP------LVHHSFSLSQIDE 455
K++ ++V N Q+L Q K+ I+ F + P L ++ +Q+D
Sbjct: 95 KVSREYARKSVHLNALQLLTQA--KAIIRLHERGVFHKWLPKDKDLDLQQIAYYQNQMDH 152
Query: 456 LISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYS 515
L+ A++ + ++L+ L ++ Y + L+ L GW + + Q
Sbjct: 153 LLDMGWRSKALETSTLAIKVALKSLKFYHNYYHIPLVVTTVLALLGWQFYQLVKLSQNVM 212
Query: 516 SLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRLIR 575
+ + I L +L + ++ +P + + + +W +
Sbjct: 213 APHYM-RRGYLTWCTIFLASLGLLLGEMVFLQWAPFMTVICLVVPFGVWCMTLAALP-QN 270
Query: 576 GLWKYLRERRADYFIKL---LFAAA---VAVVIVELLVHSFTERKLYTWFFLIAGVVASI 629
G W + + + + + A+ + + +L F R+ + ++
Sbjct: 271 GGWIFEPLKHLRWIVGPAAVMIASIYCNCPLSLAYILCVGFYNRRGWLHPSPKFLAWLAL 330
Query: 630 LLHFSIPWRSGIPVFVCISC---WFLSVFTLMPAEIP-----DNNNLVSPFLGANDTD-- 679
+L S + + ++ L +++ + +N+ +
Sbjct: 331 VLLLGGFLWSQKGMQILMTTNYRVVLQAISMLVVIVRPCVLNENHKWKVWVINGGILFVA 390
Query: 680 ---IFGWCV---ICDGVFV---------------DKAS----NAESRIAFVTSVHKLVSC 714
IF + + +F + E + ++H L+S
Sbjct: 391 AIGIFLKEMGKPVPLYLFAANWAYLIYAFASVPCSSRTTPQSRLELIRFNLLTLHVLLSD 450
Query: 715 RYEAVFYSALAVVLMAWILFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRI 774
Y ++F I ++ K KE+ E + I + ++LQ+ R
Sbjct: 451 SYVSLF------AQGLIIEYQMGLEVHEKFKEAD-------EDVKILTSSKHLQMC-YRF 496
Query: 775 PLVFMVLFNVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAF 834
+ ++ F + FGTG++ ++ +S F+ S L+ L++ L IP ++++ +
Sbjct: 497 AVSILLYFYASLFGTGHWVGGFTYLANSARLFLPDSSSGLVPLLVLIHLLIPSIVIMASV 556
Query: 835 SAITKLVRVPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVSAQVVFVL 894
A++ R + ++L + + + F V + W S+ H + V+ +L
Sbjct: 557 VALSSFGRQQIRTIFSSLMLICNAVVLFFVVFVPHNAYWPMAHPSVVHALLAQLTVILIL 616
Query: 895 LLFALTNLYTR 905
++ ++ R
Sbjct: 617 ACESIVTIFFR 627
>dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [Mus musculus]
Length = 391
Score = 528 bits (1348), Expect = e-148
Identities = 196/403 (48%), Positives = 263/403 (64%), Gaps = 20/403 (4%)
Query: 45 WLVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKFFE 104
LG+ +H V+ SIFDIYF +P+VHGM P PPAKRLVL ++DGLRAD +E
Sbjct: 3 LFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPL-PPPAKRLVLFVADGLRADTLYE 61
Query: 105 PDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPV 164
DE+G RAPF+RN+I ++G WGVSH R PTESRPGHVA+IAGFYED SAV KGWK NPV
Sbjct: 62 LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121
Query: 165 EFDSVFNQSRHTFAFGSPDIIPIFCSALP--HSTWNSYPHEYEDF-ATDASFLDEWSFDQ 221
EFDS+FN+S++T+++GSPDI+P+F H SY + EDF A DA+ LD W FD+
Sbjct: 122 EFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWVFDK 181
Query: 222 FEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERV 281
+ + + + L ++++K+V FLHLLG D+NGHAHRP S Y +N+K VD + +
Sbjct: 182 VKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEI 241
Query: 282 YHLLEDYYRDN-RTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSH 340
+ + +Y D+ +T++IFT+DHGM+D GSHG GHP+ T TP V WGAGI++P+ S +
Sbjct: 242 VSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQY 301
Query: 341 SDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGY 400
D +W L +R DVNQADIAPLM++L+G+P P+NSVG LP+GY
Sbjct: 302 DDEFL-------------KEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGY 348
Query: 401 MKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNS--LFFKPFK 441
+ + E++ N QIL Q K K + F PFK
Sbjct: 349 LNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFK 391
>pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast
(Schizosaccharomyces pombe)
dbj|BAA21454.1| (AB004539) ORF YLL031c [Schizosaccharomyces pombe]
emb|CAA16901.1| (AL021766) hypothetical protein [Schizosaccharomyces pombe]
Length = 918
Score = 469 bits (1195), Expect = e-130
Identities = 129/748 (17%), Positives = 243/748 (32%), Gaps = 134/748 (17%)
Query: 32 VASRRRWLKRRETWLVVLGVALHAVYMLSIF--DIYFKTPIVH--GMDPVPPRFSEPPAK 87
V +++ TW + A+ ++S F F + + PPA
Sbjct: 6 VKCKKKLTSTIGTWKYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPAD 65
Query: 88 -----------------RLVLLISDGLRADKFFEPDEEGKYR----APFLRNIIKNQGRW 126
R V++I D LR D ++ Y P+ +++ + +
Sbjct: 66 VREWKNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSY 125
Query: 127 GVSH-ARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFNQSRHTFAFGSPDII 185
A PT + + G + + ++ D++ Q + S D
Sbjct: 126 LTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQ------WKSLDKQ 179
Query: 186 PIFCSALPHSTWNSYPHEY--EDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDK 243
+ L TW+ H+Y E + A + + +N+ + +
Sbjct: 180 IV---LLGDDTWDVLFHDYLNETLSQPAFSFNVPDLHGVDNKVNQY----VFDYIKDANF 232
Query: 244 LVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHG 303
V+ H LG D GH P + + +D+ + + LL D+ T I DHG
Sbjct: 233 DVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL-----DDSTLLIVMGDHG 287
Query: 304 MSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGL 363
M +KG+HG ++ V W +S T K
Sbjct: 288 MDNKGNHGGDSFDEINS--VLW-------------MYSKKPTFGYLKQPG---------- 322
Query: 364 RRVERVDVNQADIAPLMSTLLGLPCPVNSVGNL-PLGYMKLNEAEEVEAVVANTKQILNQ 422
+ + NQ D+ P +S LLG P P ++G L P + + +A N Q LN+
Sbjct: 323 ---KVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEPFYYYGDEYLSKAQKINIGQ-LNR 378
Query: 423 LLRKSYIKSSNSLFFKPFKPLVHHSFSLSQIDELISAKSYEAAMKLAVDLRNLSLEGLHY 482
+ + +S+ F H + S +D+ L D + Y
Sbjct: 379 FFSEYDLDASD------FLSSSVHKNNNSYLDQYF----------LDFDYAR---DAFSY 419
Query: 483 FQTYDWLMLMTVITLGYTGWM--IVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAIL 540
F+ + + +G+ + ++Q S + +++ + CL + ++
Sbjct: 420 FKAIWAEFSLFPMIIGFLLLIIGGFNLALLMQDKSVI---FRMSANMAPSVMKCLPVCLI 476
Query: 541 SVLNLVE-HSPPLYHAY-IGMTVFLWTQIFSEYRL--IRGLWKYLRERRADYFIKLLFAA 596
+L E HSP Y + + ++ F++ + +G K DYF +F
Sbjct: 477 LILANNELHSPFPAEFYVLLPSFYILLNSFNQKLMEYFKGFVK------LDYF--SIFIT 528
Query: 597 AVAVVIVELLVHSFTERKLYTWFFLIAGVVASILLHFSIPWRSGIPVFVCISCWFLSVFT 656
+ V + E +L + + G+V + P+F C + L+ F
Sbjct: 529 FLHVCSFGSNSFTVWEDRLCHFLIITIGLVMFCK-----CFSEMSPLFACSTYSALA-FI 582
Query: 657 LMPAEIPDNNN------------LVSPFLGANDTDIFGWCVICDGVFVDKASNAESRIAF 704
L+ N +S + T I + + + R
Sbjct: 583 LLQVISSYVTNCREEQGAFCVSTYISTPDNSLRTLIVLALMALSSIILPLILQLHLRRVL 642
Query: 705 VTSVHKLVSCRYEAVFYSALAVVLMAWI 732
S+ KL F ++ WI
Sbjct: 643 GLSL-KLYHLSILYFFELISSI---FWI 666
>gb|AAF54658.1| (AE003692) CG5342 gene product [Drosophila melanogaster]
Length = 559
Score = 451 bits (1149), Expect = e-125
Identities = 110/563 (19%), Positives = 221/563 (38%), Gaps = 63/563 (11%)
Query: 371 VNQADIAPLMSTLLGLPCPVNSVGNLPLGYMKLNEAEEVEAVVANTKQILNQL--LRKSY 428
+N + LMS LLG+P PV S G LP G + + E A++ N KQ+L Q LR+ +
Sbjct: 14 LNTPHLTALMSALLGVPPPVYSRGMLPKGMLNASLRYEANAMLINAKQLLAQARRLRELH 73
Query: 429 IKSSNSLF--FKPFKPLVHHSFSLSQIDELISAKSYEAAMKLAVDLRNLSLEGLHYFQTY 486
K + + F+ V S + L + + A + + + + ++G+ YF+ Y
Sbjct: 74 PKRMPAFWLSFQMMDNFVKESLA------LKKQRRFRALLDYSCNYMPVLIKGMDYFKDY 127
Query: 487 DWLMLMTVITLGYTGWMIVLALHVL---QCYSSLSGDLSKKEHLSVYISGC--LLMAILS 541
+ +T ++ W+ L H+ +C + + VY G LL +L
Sbjct: 128 YRHVSITAVSFAGIAWIYCLRCHLTVGKKCRNLIEIQEVISSKRLVYARGFHRLLTGVLV 187
Query: 542 VLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVV 601
++ ++E P + A + + W R K L ER K L + A
Sbjct: 188 IIMMLERIPLVVQAILLIPSLYW----------RTTLKILGERPKMVCRKSLMSTA---- 233
Query: 602 IVELLVHSFTERKLYTWFFLIAGVVASILLHFSIPWRSG--IPVFVCISCWFLSVFTLMP 659
++ L+ R+ + L G + + ++ + L+V + +P
Sbjct: 234 LLALICFGGFFRR----YILAVGYLGFASYNNREAFKRRGHQFYLWLLLLLGLTVVSALP 289
Query: 660 AEIPDNNNLVSPFLGANDTDIFGWCV--ICDGVFVDKASNAESRIAFVTSVHKLVSCRYE 717
+ GA IF + + GV+++ + + + ++ ++ +
Sbjct: 290 ESLG------CSQPGALMFSIFLTVLRPLACGVYLNLLTWLSNIPVLLAALEYILIGWHP 343
Query: 718 AVFYSALAVVLMAWILFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPL- 776
+ Y + L +L++ + +S+V LS T + S + ++++ L
Sbjct: 344 WIMYLVSWIYLGFLVLWQRRNLQASEVFFFDLSTLYTLTCTSYESVVIQMLAMELQLALR 403
Query: 777 ----------------VFMVLFNVAFFGTGNFASIASF-EISSVYRFITIFSPFLMAALL 819
+V + F G+F + F +I F +SP ++
Sbjct: 404 MKLKRNESIGPKTAAHYILVYSWYSLFIIGSFPAFDDFLDILHETCF--GYSPLTYGLVM 461
Query: 820 IFKLFIPFMLVICAFSAITKLVRVPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNS 879
+ KL +P++LV+C + K + + ++L + M++ + N G W +I +
Sbjct: 462 VLKLILPWLLVLCIMAGNYKSLASYEQQIFVRLLLMNSAMSLVLLHGITNVGPWRDILSR 521
Query: 880 ISHFGIVSAQVVFVLLLFALTNL 902
+ F +V + LLL+ LT L
Sbjct: 522 FAEFAVVHVFPLVWLLLWRLTQL 544
>dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:1351629,
evidence:ISS~phosphatidylinositol glycan, class
N~putative [Mus musculus]
Length = 320
Score = 422 bits (1076), Expect = e-116
Identities = 156/311 (50%), Positives = 211/311 (67%), Gaps = 5/311 (1%)
Query: 45 WLVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKFFE 104
LG+ +H V+ SIFDIYF +P+VHGM P PPAKRLVL ++DGLRAD +E
Sbjct: 3 LFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPL-PPPAKRLVLFVADGLRADTLYE 61
Query: 105 PDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPV 164
DE+G RAPF+RN+I ++G WGVSH R PTESRPGHVA+IAGFYED SAV KGWK NPV
Sbjct: 62 LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121
Query: 165 EFDSVFNQSRHTFAFGSPDIIPIFCSALP--HSTWNSYPHEYEDF-ATDASFLDEWSFDQ 221
E DS+FN+ ++T+++GSPDI+P+F H SY + EDF A DA+ LD W FD+
Sbjct: 122 ESDSLFNERKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWVFDK 181
Query: 222 FEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERV 281
+ + + + L ++++K+V FLHLLG D+NGHAHRP S Y +N+K VD + +
Sbjct: 182 VKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEI 241
Query: 282 YHLLEDYYRDN-RTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSH 340
+ + +Y D+ +T++IFT+DHGM+D GSHG GHP+ T TP V WGAGI++P+ S +
Sbjct: 242 VSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQY 301
Query: 341 SDSVTTFVDKH 351
D +
Sbjct: 302 DDEFLKGTNIF 312
>ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans]
Length = 348
Score = 414 bits (1054), Expect = e-114
Identities = 160/383 (41%), Positives = 237/383 (61%), Gaps = 42/383 (10%)
Query: 44 TW-LVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKF 102
+W ++ + +H V + SIFD+Y+ +P+VHG+ P E PAKR+ ++ +DGLR D F
Sbjct: 2 SWKFLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDTF 61
Query: 103 FEPDEEGKYRAPFLRNIIK-NQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKA 161
+ ++ P+L +I+ +G +G+S + PTESRPGHVAI AG ED SAV KGWK
Sbjct: 62 NKYPDKS----PYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKK 117
Query: 162 NPVEFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTWNSYPHEYEDFAT-DASFLDEWSFD 220
NPV+FDSVFN+S +++ +GSPDI+ +F LP++ SY + EDFA+ DAS LD+W F+
Sbjct: 118 NPVQFDSVFNRSSYSWMWGSPDIVNLFDD-LPNAESFSYSADEEDFASKDASNLDKWVFE 176
Query: 221 QFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAER 280
FE L + D L + + + K + FLHLLG D+NGH ++P S Y++N+KVVD E+
Sbjct: 177 HFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEK 236
Query: 281 VYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSH 340
V HL++ ++ D++T+++FT+DHGM+D GSHG G TP VAWGAG++ P
Sbjct: 237 VQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGGP------ 290
Query: 341 SDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGY 400
++D+NQ D+APL+S L+G P PVNS+G LP+
Sbjct: 291 ---------------------------KLDLNQIDLAPLISALIGCPIPVNSMGILPVQM 323
Query: 401 MKLN-EAEEVEAVVANTKQILNQ 422
M + E +A+ AN KQ++N
Sbjct: 324 MNSKGSSYEFKAIEANFKQVINL 346
>gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melanogaster]
Length = 880
Score = 344 bits (874), Expect = 5e-93
Identities = 106/553 (19%), Positives = 190/553 (34%), Gaps = 98/553 (17%)
Query: 42 RETWL-VVLGVALHAVYMLSIFDIYF-----------------KTPIVHGMDPVPPRFSE 83
++WL +G+ + +F I F + + GM+ PP
Sbjct: 4 HKSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPP---P 60
Query: 84 PPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVA 143
P VLL+ D LR D P + + + H PT + P +
Sbjct: 61 PAYDSFVLLLVDALRDDF------PDATSMPVAYSRACEKLK---LHVDIPTVTMPRLKS 111
Query: 144 IIAGFYEDPSAVTKGWKANPVEFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTW-NSYPH 202
I G + + DS ++ + S TW +P
Sbjct: 112 ITTGTLSNFIDIALNVGHTEQMQDSFLHRLKQQ---------NRVVSFAGDHTWVKLFPS 162
Query: 203 EYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRP 262
E+ + F + + + ++ EL D ++ LH LG D GH
Sbjct: 163 EFTRQVENHDSFYVNDFYEGDRNVTKTLET----ELERSDWSLLILHYLGLDHIGHVEGN 218
Query: 263 YSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPL 322
S +K +D++ +++ + + + T DHGM+D G HG P T PL
Sbjct: 219 ASPRVPLKLKEMDEVVKKILDH-KSFPN---VLLMLTGDHGMADGGGHGGNTPAETLVPL 274
Query: 323 VAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMST 382
+ N+ S + + NQ D+AP +S
Sbjct: 275 YLY-----------YNNCSKTPSASK---------------------RYNQIDLAPTLSV 302
Query: 383 LLGLPCPVNSVGNLPLGYM-KLNEAEEVEAVVANTKQILNQLLRK----SYIKSSNSLFF 437
LL + P S+G L + L+ ++ A N +LN+ K +S ++
Sbjct: 303 LLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLLNKARVKFGHEIVHRSDYYTWY 362
Query: 438 KPFKPLVHHSFS-LSQIDELISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVIT 496
+ L L + D +++ Y KL + L L+GL WL ++ +
Sbjct: 363 QNATLLHKKLLRPLREGDGGGASQVYYQNAKL--NYMRLQLDGLKV--GQLWLSVIAAVV 418
Query: 497 LGYTGWMIVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAY 556
L YT ++ + S L ++VY++ + A+L + PPLY
Sbjct: 419 LNYT---SHALDIIMTSSTLYSILLLVPISIAVYLTIDVAQALLKIAL-----PPLYTRR 470
Query: 557 IGMTVFLWTQIFS 569
+ +++ L + +
Sbjct: 471 LKISIPLPLPLLA 483
>gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarrowia lipolytica]
Length = 860
Score = 321 bits (817), Expect = 2e-86
Identities = 87/420 (20%), Positives = 154/420 (35%), Gaps = 42/420 (10%)
Query: 41 RRETWLVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRAD 100
+R T V + V A +L ++ G +E P ++ ++++ D R+D
Sbjct: 4 KRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYT-ESRVSTEAPFQKAIIMVVDAFRSD 62
Query: 101 KFFEPDEEGKYRAPFLRNIIKNQGRWGV-SHARPPTESRPGHVAIIAGFYEDPSAVTKGW 159
F + P L I + G +H+ PPT + P + G +
Sbjct: 63 FAF----SDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNI 118
Query: 160 KANPVEFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTW-NSYPHEYEDFATDASFLDEWS 218
+ S A S D I TW +P ++D ASF
Sbjct: 119 AE--SDNSSTLANQDSWLAQASRDGRKI--HMFGDDTWIKLFPGMFDDCEGTASFF-VSD 173
Query: 219 FDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIA 278
+ + + + R D +L + + V+ LH LG D GH P S K +D I
Sbjct: 174 YTEVDNNVTRH-IDTQLDQK--TEWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIF 230
Query: 279 ERVYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGN 338
+++Y+ D+ T I DHGM++ G+HG T +V + +
Sbjct: 231 DKLYNS-----CDDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFETAQLTETA 285
Query: 339 SHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPL 398
S P W ++Q D+ P ++ LLGL P N++G L
Sbjct: 286 ETS----------------PLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVS 329
Query: 399 GYMKLNE-AEEVEAVVANTKQILNQLLRKSYIKSSNSL-FFKPFKPLVHHSFSLSQIDEL 456
+ L +++ + N Q++ Q+L+ + S++ ++ + L + S D
Sbjct: 330 QMLGLWSPEDQLNVLKNNADQMV-QILQGQASRESDAKEVYELYDTLNS---NPSVKDYY 385
>pir||T02245 hypothetical protein P1.11659_3 - human
gb|AAC07985.1| (AC004472) P1.11659_3 [Homo sapiens]
Length = 880
Score = 311 bits (789), Expect = 4e-83
Identities = 61/403 (15%), Positives = 112/403 (27%), Gaps = 89/403 (22%)
Query: 53 LHAVYMLSIFDIY-----FKTPIV---HGMDPVPPRFSEP-------------------- 84
+ F Y F + + + P
Sbjct: 6 VLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGACWMAS 65
Query: 85 PAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAI 144
R+VL++ D LR D +R ++ + R S PPT + A+
Sbjct: 66 RFSRVVLVLIDALRFDFAQPQH---SHRILEIQP---HHARLYRSQVDPPTTTMQRLKAL 119
Query: 145 IAGFYEDPSAVTKGWKANPVEFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTWNSYPHEY 204
G + ++ + D++ Q + TW
Sbjct: 120 TTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRR---------VVFMGDDTWKDLFPGA 170
Query: 205 EDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYS 264
A + D + + + + V+ H LG D GH H P+
Sbjct: 171 FSKAFFFPSFNVRDLDTVDNGILEHLYPT----MDSGEWDVLIAHFLGVDHCGHKHGPHH 226
Query: 265 SIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVA 324
+ +D++ + + LE N T + DHGM+ G HG L
Sbjct: 227 PEMAKKLSQMDQVIQGLVERLE-----NDTLLVVAGDHGMTTNGDHGGDSELEVSAALFL 281
Query: 325 WGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLL 384
+ +P + + +P Q + P ++ LL
Sbjct: 282 YSPTAVFP-------------STPPEEPEVIP----------------QVSLVPTLALLL 312
Query: 385 GLPCPVNSVGNLPLGYMKL--------NEAEEVEAVVANTKQI 419
GLP P ++G + + + A+ N +Q+
Sbjct: 313 GLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQV 355
>gb|AAH03264.1|AAH03264 (BC003264) ectonucleotide pyrophosphatase/phosphodiesterase 2 [Mus
musculus]
Length = 862
Score = 309 bits (786), Expect = 1e-82
Identities = 52/319 (16%), Positives = 88/319 (27%), Gaps = 50/319 (15%)
Query: 78 PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTES 137
P F PP L++ DG RA ++G P + + PT++
Sbjct: 157 PAGFVRPP---LIIFSVDGFRASYM----KKGSKVMPNIEKLRSCGTHAPYMRPVYPTKT 209
Query: 138 RPGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFN-----QSRHTFAFGSPDIIPIFCSAL 192
P + G Y + + +PV FD+ F+ + H + G P I +
Sbjct: 210 FPNLYTLATGLYPESHGIVGNSMYDPV-FDATFHLRGREKFNHRWWGGQPLWITATKQGV 268
Query: 193 PHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLG 252
T F S L ++ V +
Sbjct: 269 RAGT----------------FFWSVSIPH---ERRILTILQWLSLPDNERPSVYAFYSEQ 309
Query: 253 CDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSD------ 306
D +GH + P+ N ++ +DK ++ L+ + IF DHGM D
Sbjct: 310 PDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRT 369
Query: 307 --KGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVD-------KHAHDMPT 357
++ T P G PK + + M
Sbjct: 370 EFLSNYLTNVDDITLVPGTL---GRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQ 426
Query: 358 PYDWGLRRVERVDVNQADI 376
L + +
Sbjct: 427 HLPKRLHYANNRRIEDLHL 445
>ref|NP_056559.1| (NM_015744) phosphodiesterase I/nucleotide pyrophosphatase 2 [Mus
musculus]
gb|AAD46480.1|AF123542_1 (AF123542) phosphodiesterase I/nucleotide pyrophosphatase [Mus
musculus]
Length = 862
Score = 309 bits (785), Expect = 1e-82
Identities = 52/319 (16%), Positives = 88/319 (27%), Gaps = 50/319 (15%)
Query: 78 PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTES 137
P F PP L++ DG RA ++G P + + PT++
Sbjct: 157 PAGFVRPP---LIIFSVDGFRASYM----KKGSKVMPNIEKLRSCGTHAPYMRPVYPTKT 209
Query: 138 RPGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFN-----QSRHTFAFGSPDIIPIFCSAL 192
P + G Y + + +PV FD+ F+ + H + G P I +
Sbjct: 210 FPNLYTLATGLYPESHGIVGNSMYDPV-FDATFHLRGREKFNHRWWGGQPLWITATKQGV 268
Query: 193 PHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLG 252
T F S L ++ V +
Sbjct: 269 RAGT----------------FFWSVSIPH---ERRILTILQWLSLPDNERPSVYAFYSEQ 309
Query: 253 CDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSD------ 306
D +GH + P+ N ++ +DK ++ L+ + IF DHGM D
Sbjct: 310 PDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRT 369
Query: 307 --KGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVD-------KHAHDMPT 357
++ T P G PK + + M
Sbjct: 370 EFLSNYLTNVDDITLVPGTL---GRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQ 426
Query: 358 PYDWGLRRVERVDVNQADI 376
L + +
Sbjct: 427 HLPKRLHYANNRRIEDLHL 445
>dbj|BAA08260.1| (D45421) phosphodiesterase I alpha [Homo sapiens]
Length = 863
Score = 305 bits (775), Expect = 2e-81
Identities = 51/319 (15%), Positives = 88/319 (26%), Gaps = 50/319 (15%)
Query: 78 PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTES 137
P F PP L++ DG RA ++G P + + PT++
Sbjct: 158 PAGFVRPP---LIIFSVDGFRASYM----KKGSKVMPNIEKLRSCGTHSPYMRPVYPTKT 210
Query: 138 RPGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFN-----QSRHTFAFGSPDIIPIFCSAL 192
P + G Y + + +PV FD+ F+ + H + G P I +
Sbjct: 211 FPNLYTLATGLYPESHGIVGNSMYDPV-FDATFHLRGREKFNHRWWGGQPLWITATKQGV 269
Query: 193 PHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLG 252
T F L H+ V +
Sbjct: 270 KAGT----------------FFWSVVIPH---ERRILTILQWLTLPDHERPSVYAFYSEQ 310
Query: 253 CDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSD------ 306
D +GH + P+ N ++ +DKI ++ L+ + IF DHGM D
Sbjct: 311 PDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRT 370
Query: 307 --KGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVD-------KHAHDMPT 357
++ T P G K ++ + +
Sbjct: 371 EFLSNYLTNVDDITLVPGTL---GRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQ 427
Query: 358 PYDWGLRRVERVDVNQADI 376
L + +
Sbjct: 428 HLPKRLHYANNRRIEDIHL 446
>ref|NP_006200.1| (NM_006209) ectonucleotide pyrophosphatase/phosphodiesterase 2
(autotaxin); Phosphodiesterase I/nucleotide
pyrophosphatase 2; autotaxin; phosphodiesterase
I/nucleotide pyrophosphatase 2 (autotaxin) [Homo
sapiens]
gb|AAB00855.1| (L46720) autotaxin-t [Homo sapiens]
Length = 863
Score = 305 bits (775), Expect = 2e-81
Identities = 51/319 (15%), Positives = 88/319 (26%), Gaps = 50/319 (15%)
Query: 78 PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTES 137
P F PP L++ DG RA ++G P + + PT++
Sbjct: 158 PAGFVRPP---LIIFSVDGFRASYM----KKGSKVMPNIEKLRSCGTHSPYMRPVYPTKT 210
Query: 138 RPGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFN-----QSRHTFAFGSPDIIPIFCSAL 192
P + G Y + + +PV FD+ F+ + H + G P I +
Sbjct: 211 FPNLYTLATGLYPESHGIVGNSMYDPV-FDATFHLRGREKFNHRWWGGQPLWITATKQGV 269
Query: 193 PHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLG 252
T F L H+ V +
Sbjct: 270 KAGT----------------FFWSVVIPH---ERRILTILQWLTLPDHERPSVYAFYSEQ 310
Query: 253 CDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSD------ 306
D +GH + P+ N ++ +DKI ++ L+ + IF DHGM D
Sbjct: 311 PDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRT 370
Query: 307 --KGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVD-------KHAHDMPT 357
++ T P G K ++ + +
Sbjct: 371 EFLSNYLTNVDDITLVPGTL---GRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQ 427
Query: 358 PYDWGLRRVERVDVNQADI 376
L + +
Sbjct: 428 HLPKRLHYANNRRIEDIHL 446
>ref|NP_476445.1| (NM_057104) phosphodiesterase I/nucleotide pyrophosphatase 2;
phosphodiesterase I/nucleotide pyrophosphatase 2
(autotaxin) [Rattus norvegicus]
pir||A55453 plasma cell membrane glycoprotein PC-1, brain specific - rat
dbj|BAA05910.1| (D28560) phosphodiesterase I [Rattus norvegicus]
Length = 885
Score = 305 bits (775), Expect = 2e-81
Identities = 49/327 (14%), Positives = 87/327 (25%), Gaps = 53/327 (16%)
Query: 73 GMDPVPPRF---SEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVS 129
PP L++ DG RA ++G P + + +
Sbjct: 147 AARNQSSECLQVCPPP---LIIFSVDGFRASYM----KKGSKVMPNIEKLRSCGTHVPYT 199
Query: 130 HARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFN-----QSRHTFAFGSPDI 184
PT++ P + G Y + + +PV FD+ F+ + H + G P
Sbjct: 200 RPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPV-FDASFHLRGREKFNHRWWGGQPLW 258
Query: 185 IPIFCSALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKL 244
I + T F S L ++
Sbjct: 259 ITATKQGVRAGT----------------FFWSVSIPH---ERRILTILQWLSLPDNERPS 299
Query: 245 VVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGM 304
V + D +GH + P+ N ++ +DK ++ L+ + IF DHGM
Sbjct: 300 VYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHGM 359
Query: 305 SD--------KGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVD------- 349
D ++ T P G K + + +
Sbjct: 360 EDVTCDRTEFLSNYLTNVDDITLVPGTL---GRIRAKSINNSKYDPKTIIANLTCKKPDQ 416
Query: 350 KHAHDMPTPYDWGLRRVERVDVNQADI 376
M L + +
Sbjct: 417 HFKPYMKQHLPKRLHYANNRRIEDIHL 443
>gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melanogaster]
Length = 1077
Score = 300 bits (761), Expect = 9e-80
Identities = 73/391 (18%), Positives = 138/391 (34%), Gaps = 65/391 (16%)
Query: 76 PVPPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIK---------NQGRW 126
P ++++L+ D L+ + P+ ++ + R
Sbjct: 66 NASSNLCLPQKSKVIVLVVDALKYEFGL-YRANATDPLPYENKLVVLQELLQQNPDHARL 124
Query: 127 GVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFNQSRHTFAFGSPDIIP 186
A PPT + + G + + + + D++ +Q D+
Sbjct: 125 MRFRADPPTTTLQRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQ------IVKNDLPV 178
Query: 187 IFCSALPHSTW-NSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLV 245
+F L STW + YPH ++ + D + D + + + KEL +D V
Sbjct: 179 VF---LGDSTWTDLYPHRFKRSYSY-PSFDIFDLDSVDNEILKHLP----KELESKDWQV 230
Query: 246 VFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMS 305
+ H LG D GH H P + ++++ V + DN T+ + DHGM+
Sbjct: 231 LVAHFLGVDHCGHKHGPMHEEMARKLGEMNEVIRSVVAAM-----DNDTTLLVMGDHGMT 285
Query: 306 DKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRR 365
G HG T+ L A+ ++ SG SDS
Sbjct: 286 ASGDHGGDTDDETNALLFAYSKQHRFYGNDSG---SDSEM-------------------- 322
Query: 366 VERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGYMKLNEAEEVEAVVANTKQILNQLLR 425
+ Q D+ P ++T+LG+P P +++G + + + N Q L
Sbjct: 323 -----LQQIDLVPTLATILGVPIPYSNLGLVNFNIVPD-----LRVPHLNKFQTLLLHSW 372
Query: 426 KSYIKSSNSLFFKPFKPLVHHSFSLSQIDEL 456
++ + F + +F++ Q+D L
Sbjct: 373 QNAQQIYRYFF--QYALENKRTFNVEQMDHL 401
>ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thaliana]
gb|AAF18652.1| (AC006592) unknown protein [Arabidopsis thaliana]
Length = 897
Score = 298 bits (757), Expect = 3e-79
Identities = 86/420 (20%), Positives = 155/420 (36%), Gaps = 69/420 (16%)
Query: 41 RRETWLVVLGVALHAVYM-LSIFDIYFKTPIVHGMDPVPPRFSE---------------P 84
R T V G+ L + + + +F + P + G+ P
Sbjct: 9 TRLTIFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHP 68
Query: 85 PAKRLVLLISDGLRADKFFEPDEEGK-----YRAPFLRNIIKNQGRWGV-SHARPPTESR 138
RL+ + DGL A+ D + P+ ++++ N G + A PPT +
Sbjct: 69 EKLRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTM 128
Query: 139 PGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTW- 197
P A+++G V + + D++ Q L TW
Sbjct: 129 PRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMV---------MLGDETWL 179
Query: 198 NSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNG 257
+P + +SF + Q + ++R D EL D ++ LH LG D G
Sbjct: 180 KLFPGLFMRHDGVSSFFVK-DTVQVDRNVSRHLPD----ELNSDDWNLLILHYLGLDHVG 234
Query: 258 HAHRPYSSIYLNNVKVVDKIAERVY--HLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHP 315
H S + +K +D I ++ +++ + +T I +DHGM++ G+HG
Sbjct: 235 HTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSY 294
Query: 316 TNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQAD 375
TD+ ++ G + + S + Q D
Sbjct: 295 EETDSLMLFIG-----------LNSNISDYASATNNVAF------------------QVD 325
Query: 376 IAPLMSTLLGLPCPVNSVGNLPLGYM-KLNEAEEVEAVVANTKQILNQLLRKSYIKSSNS 434
+AP ++ L G+P P N+VG L G + L + E++ A+ N+ Q+L +L + S
Sbjct: 326 LAPTLALLFGVPIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLRLMLAQIQSSSFPR 385
>ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class O [Mus musculus]
dbj|BAA96254.1| (AB038560) Pig-o [Mus musculus]
Length = 1101
Score = 296 bits (751), Expect = 1e-78
Identities = 68/419 (16%), Positives = 115/419 (27%), Gaps = 97/419 (23%)
Query: 51 VALHAVYMLSIFDIY-----FKTPIV---HGMDPVPP--------------------RFS 82
V++ F Y F + + + +
Sbjct: 12 VSVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNQSSCQELPGPGPLPWGSHGKPGACWM 71
Query: 83 EPPAKRLVLLISDGLRADKFFEP----DEEGKYRAPFLRNIIK---------NQGRWGVS 129
R+VL++ D LR D E PFL + + GR S
Sbjct: 72 PSRFSRVVLVLIDALRFDFAQPQRSHVPGEPPVSVPFLGKLGSLQRILESQPHHGRLYRS 131
Query: 130 HARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFNQSRHTFAFGSPDIIPIFC 189
PPT + A+ G + ++ + D+V Q
Sbjct: 132 QVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNVIQQLNSAGRR---------V 182
Query: 190 SALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLH 249
+ TW A S + + + L V+ H
Sbjct: 183 VFMGDDTWRDLFPGAFSQAFFFSSFNVRDLHTVDNGILEHLYPT----LDGGSWDVLIAH 238
Query: 250 LLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGS 309
LG D GH H P+ + +D++ + + LE N T + DHGM+ G
Sbjct: 239 FLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLIERLE-----NDTLLVVAGDHGMTMNGD 293
Query: 310 HGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERV 369
HG L + +P + + +P
Sbjct: 294 HGGDSELEVSAALFLYSPTALFP-------------SVPPEEPEVIP------------- 327
Query: 370 DVNQADIAPLMSTLLGLPCPVNSVGNLPLGYMKL---------NEAEEVEAVVANTKQI 419
Q + P ++ LLGLP P + G + + +V A+ N +Q+
Sbjct: 328 ---QVSLVPTLALLLGLPIPFGNTGEVMAELFSGGSDSSHPHSSALAQVSALHINAQQV 383
>gb|AAB61536.1| (U78788) alkaline phosphodiesterase [Rattus norvegicus]
Length = 875
Score = 291 bits (739), Expect = 3e-77
Identities = 47/320 (14%), Positives = 94/320 (28%), Gaps = 26/320 (8%)
Query: 75 DPVPP-RFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARP 133
+P P F +PP ++L DG RA+ P + + A
Sbjct: 150 EPQCPEGFDQPP---VILFSMDGFRAEYLQ----TWSTLLPNINKLKTCGLHSKYMRAMY 202
Query: 134 PTESRPGHVAIIAGFYEDPSAVTKGWKAN---PVEFD-SVFNQSRHTFAFGSPDIIPIFC 189
PT++ P H I+ G Y + + + F S +S + G P +
Sbjct: 203 PTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWSGQPIWLTAMY 262
Query: 190 SALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLH 249
L +++ +P + + + L + ++
Sbjct: 263 QGLKAASYY-WPGSDVAVNGSFPNIYRNYSNSVPYESRIATLLQWLDLPKAERPSFYTIY 321
Query: 250 LLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKG- 308
+ DS GH P S+ + +++VD + L+ N + I ADHGM
Sbjct: 322 VEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHNCVNIIVLADHGMDQTSC 381
Query: 309 ---SHGDGHPTNTDTPLVAWGAGIQYPKPASGNSH---------SDSVTTFVDKHAHDMP 356
+ + + + A + + S +
Sbjct: 382 DRVEYMTDYFPEINFYMYQGPAPRIRTRNIPQDFFTFNSEEIVRDLSCRKSDQHFKPYLT 441
Query: 357 TPYDWGLRRVERVDVNQADI 376
L + V +++ +
Sbjct: 442 PDLPKRLHYAKNVRIDKVHL 461
>ref|NP_062243.1| (NM_019370) alkaline phosphodiesterase [Rattus norvegicus]
gb|AAB61535.1| (U78787) alkaline phosphodiesterase [Rattus norvegicus]
Length = 875
Score = 290 bits (737), Expect = 5e-77
Identities = 47/320 (14%), Positives = 94/320 (28%), Gaps = 26/320 (8%)
Query: 75 DPVPP-RFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARP 133
+P P F +PP ++L DG RA+ P + + A
Sbjct: 150 EPQCPEGFDQPP---VILFSMDGFRAEYLQ----TWSTLLPNINKLKTCGLHSKYMRAVY 202
Query: 134 PTESRPGHVAIIAGFYEDPSAVTKGWKAN---PVEFD-SVFNQSRHTFAFGSPDIIPIFC 189
PT++ P H I+ G Y + + + F S +S + G P +
Sbjct: 203 PTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWSGQPIWLTAMY 262
Query: 190 SALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLH 249
L +++ +P + + + L + ++
Sbjct: 263 QGLKAASYY-WPGSDVAVNGSFPNIYRNYSNSVPYESRIATLLQWLDLPKAERPSFYTIY 321
Query: 250 LLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKG- 308
+ DS GH P S+ + +++VD + L+ N + I ADHGM
Sbjct: 322 VEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHNCVNIIVLADHGMDQTSC 381
Query: 309 ---SHGDGHPTNTDTPLVAWGAGIQYPKPASGNSH---------SDSVTTFVDKHAHDMP 356
+ + + + A + + S +
Sbjct: 382 DRVEYMTDYFPEINFYMYQGPAPRIRTRNIPQDFFTFNSEEIVRDLSCRKSDQHFKPYLT 441
Query: 357 TPYDWGLRRVERVDVNQADI 376
L + V +++ +
Sbjct: 442 PDLPKRLHYAKNVRIDKVHL 461
>dbj|BAA06333.1| (D30649) phosphodiesterase I [Rattus norvegicus]
Length = 876
Score = 290 bits (737), Expect = 5e-77
Identities = 47/320 (14%), Positives = 94/320 (28%), Gaps = 26/320 (8%)
Query: 75 DPVPP-RFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARP 133
+P P F +PP ++L DG RA+ P + + A
Sbjct: 150 EPQCPEGFDQPP---VILFSMDGFRAEYLQ----TWSTLLPNINKLKTCGLHSKYMRAVY 202
Query: 134 PTESRPGHVAIIAGFYEDPSAVTKGWKAN---PVEFD-SVFNQSRHTFAFGSPDIIPIFC 189
PT++ P H I+ G Y + + + F S +S + G P +
Sbjct: 203 PTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWSGQPIWLTAMY 262
Query: 190 SALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLH 249
L +++ +P + + + L + ++
Sbjct: 263 QGLKAASYY-WPGSDVAVNGSFPNIYRNYSNSVPYESRIATLLQWLDLPKAERPSFYTIY 321
Query: 250 LLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKG- 308
+ DS GH P S+ + +++VD + L+ N + I ADHGM
Sbjct: 322 VEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHNCVNIIVLADHGMDQTSC 381
Query: 309 ---SHGDGHPTNTDTPLVAWGAGIQYPKPASGNSH---------SDSVTTFVDKHAHDMP 356
+ + + + A + + S +
Sbjct: 382 DRVEYMTDYFPEINFYMYQGPAPRIRTRNIPQDFFTFNSEEIVRDLSCRKSDQHFKPYLT 441
Query: 357 TPYDWGLRRVERVDVNQADI 376
L + V +++ +
Sbjct: 442 PDLPKRLHYAKNVRIDKVHL 461
>pir||A57080 cell surface antigen RB13-6 - rat
emb|CAA88029.1| (Z47987) RB13-6 antigen [Rattus norvegicus]
Length = 875
Score = 287 bits (729), Expect = 5e-76
Identities = 46/320 (14%), Positives = 93/320 (28%), Gaps = 26/320 (8%)
Query: 75 DPVPP-RFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARP 133
+P P F +PP ++L DG RA+ P + + A
Sbjct: 150 EPQCPEGFDQPP---VILFSMDGFRAEYLQ----TWSTLLPNINKLKTCGLHSKYMRAMY 202
Query: 134 PTESRPGHVAIIAGFYEDPSAVTKGWKAN---PVEFD-SVFNQSRHTFAFGSPDIIPIFC 189
PT++ P H I+ G Y + + + F S +S + G P +
Sbjct: 203 PTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWSGQPIWLTAMY 262
Query: 190 SALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLH 249
L +++ + + + + L + ++
Sbjct: 263 QGLKAASYY-WLGSDVAVNGSFPNIYRNYSNSVPYESRIATLLQWLDLPKAERPSFYTIY 321
Query: 250 LLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKG- 308
+ DS GH P S+ + +++VD + L+ N + I ADHGM
Sbjct: 322 VEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHNCVNIIVLADHGMDQTSC 381
Query: 309 ---SHGDGHPTNTDTPLVAWGAGIQYPKPASGNSH---------SDSVTTFVDKHAHDMP 356
+ + + + A + + S +
Sbjct: 382 DRVEYMTDYFPEINFYMYQGPAPRIRTRNIPQDFFTFNSEEIVRDLSCRKSDQHFKPYLT 441
Query: 357 TPYDWGLRRVERVDVNQADI 376
L + V +++ +
Sbjct: 442 PDLPKRLHYAKNVRIDKVHL 461
>ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) biosynthesis; Gpi13p
[Saccharomyces cerevisiae]
pir||S64782 probable membrane protein YLL031c - yeast (Saccharomyces
cerevisiae)
emb|CAA97480.1| (Z73136) ORF YLL031c [Saccharomyces cerevisiae]
Length = 1017
Score = 284 bits (721), Expect = 4e-75
Identities = 60/385 (15%), Positives = 120/385 (30%), Gaps = 59/385 (15%)
Query: 30 VVVASR-RRWLKRRETWLVVLGVALHAVYMLSIFDIYFKTPIVH------GMDPV-PPRF 81
++ SR +++ K + ++ + + + I +F + +
Sbjct: 19 IIYKSRIKKFQKNHK--FYII-LLVFIAILQFISIAFFTRGFLLSRHVLDNISSQNETSK 75
Query: 82 SEPPAKRLVLLISDGLRADKFFEPDEE-GKYRAPFLRNIIKNQGRWGVSH---------- 130
P + V+L+ D LR D +E Y + NI+ +
Sbjct: 76 LPPRFNKAVILVIDALRFDFAIPVNESHSNYNLNYHNNILSLYDSFASDKDASSLLLKFI 135
Query: 131 ARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFNQSRHTFAFGSPDIIPIFCS 190
A PPT + + G + +E D+ Q +
Sbjct: 136 ADPPTTTLQRLKGLTTGSLPTFIDAGSNFDGTVIEEDNFLKQL---------HLANKTVK 186
Query: 191 ALPHSTWNSYPHEYEDFATDAS-FLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLH 249
TW + H + + L+ W D + + D + ++ V+ H
Sbjct: 187 FAGDDTWMALFHPFLSNDSFPLESLNVWDLDTVDNGVMDYFHDHLQQ---DKEWDVMIGH 243
Query: 250 LLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGS 309
+LG D GH + P VD+ + + D+ T + DHGM G+
Sbjct: 244 MLGIDHVGHKYGPDHFTMREKQIQVDQFIDWILKS-----IDDDTLLVILGDHGMDHTGN 298
Query: 310 HGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERV 369
HG ++ L + + ++++ +
Sbjct: 299 HGGDSIDELESTLFLYSKKPDMWRLKETSNYNIDNL-------------------GHDYR 339
Query: 370 DVNQADIAPLMSTLLGLPCPVNSVG 394
V Q D+ ++ L+G P P N++G
Sbjct: 340 SVRQIDLVSSLALLMGQPIPFNNLG 364
>dbj|BAA02053.1| (D12485) The first in-frame ATG codon is located at nucleotides
17-19, followed by a second ATG codon 52 codons
downstream. And the second ATG codon is potential
initiation point for translation of NPPase. [Homo
sapiens]
Length = 930
Score = 283 bits (717), Expect = 1e-74
Identities = 51/321 (15%), Positives = 92/321 (27%), Gaps = 35/321 (10%)
Query: 75 DPV-PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARP 133
+P P F PP +L DG RA+ P + + K
Sbjct: 205 EPQCPAGFETPPT---LLFSLDGFRAEYLH----TWGGLLPVISKLKKCGTYTKNMRPVY 257
Query: 134 PTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSV----FNQSRHTFAFGSPDIIPIFC 189
PT++ P H +I+ G Y + + +P S + + G P +
Sbjct: 258 PTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAKY 317
Query: 190 SALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLH 249
L T+ +P + + + L+ + L+
Sbjct: 318 QGLKSGTFF-WPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLY 376
Query: 250 LLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMS---- 305
L DS+GH++ P SS + ++ VD + + L++ + I +DHGM
Sbjct: 377 LEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSC 436
Query: 306 ----DKGSHGDGHPTNTDTPLVAWG-AGIQYP--KPASGNSHSDSVTTFVD-------KH 351
+ V +G A P P S +
Sbjct: 437 KKYIYLNKYLGDVKNIK----VIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHF 492
Query: 352 AHDMPTPYDWGLRRVERVDVN 372
+ L + +
Sbjct: 493 KPYLKHFLPKRLHFAKSDRIE 513
>pir||A39216 plasma cell membrane glycoprotein PC-1 - human
gb|AAF36094.1| (AF110304) PDNP1 [Homo sapiens]
emb|CAC39442.1| (AJ242020) plasma cell membrane glycoprotein [Homo sapiens]
Length = 925
Score = 282 bits (716), Expect = 2e-74
Identities = 51/321 (15%), Positives = 92/321 (27%), Gaps = 35/321 (10%)
Query: 75 DPV-PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARP 133
+P P F PP +L DG RA+ P + + K
Sbjct: 200 EPQCPAGFETPPT---LLFSLDGFRAEYLH----TWGGLLPVISKLKKCGTYTKNMRPVY 252
Query: 134 PTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSV----FNQSRHTFAFGSPDIIPIFC 189
PT++ P H +I+ G Y + + +P S + + G P +
Sbjct: 253 PTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAKY 312
Query: 190 SALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLH 249
L T+ +P + + + L+ + L+
Sbjct: 313 QGLKSGTFF-WPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLY 371
Query: 250 LLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMS---- 305
L DS+GH++ P SS + ++ VD + + L++ + I +DHGM
Sbjct: 372 LEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSC 431
Query: 306 ----DKGSHGDGHPTNTDTPLVAWG-AGIQYP--KPASGNSHSDSVTTFVD-------KH 351
+ V +G A P P S +
Sbjct: 432 KKYIYLNKYLGDVKNIK----VIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHF 487
Query: 352 AHDMPTPYDWGLRRVERVDVN 372
+ L + +
Sbjct: 488 KPYLKHFLPKRLHFAKSDRIE 508
>ref|NP_006199.1| (NM_006208) ectonucleotide pyrophosphatase/phosphodiesterase 1;
phosphodiesterase I/nucleotide pyrophosphatase 1
(homologous to mouse Ly-41 antigen); plasma-cell
membrane glycoprotein [Homo sapiens]
sp|P22413|PC1_HUMAN ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (PLASMA-CELL
MEMBRANE GLYCOPROTEIN PC-1) [INCLUDES: ALKALINE
PHOSPHODIESTERASE I ; NUCLEOTIDE PYROPHOSPHATASE
(NPPASE)]
gb|AAA63237.1| (M57736) plasma cell membrane glycoprotein PC-1 [Homo sapiens]
dbj|BAA02054.1| (D12485) NPPase [Homo sapiens]
Length = 873
Score = 280 bits (710), Expect = 9e-74
Identities = 51/321 (15%), Positives = 92/321 (27%), Gaps = 35/321 (10%)
Query: 75 DPV-PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARP 133
+P P F PP +L DG RA+ P + + K
Sbjct: 148 EPQCPAGFETPPT---LLFSLDGFRAEYLH----TWGGLLPVISKLKKCGTYTKNMRPVY 200
Query: 134 PTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSV----FNQSRHTFAFGSPDIIPIFC 189
PT++ P H +I+ G Y + + +P S + + G P +
Sbjct: 201 PTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAKY 260
Query: 190 SALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLH 249
L T+ +P + + + L+ + L+
Sbjct: 261 QGLKSGTFF-WPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLY 319
Query: 250 LLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMS---- 305
L DS+GH++ P SS + ++ VD + + L++ + I +DHGM
Sbjct: 320 LEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSC 379
Query: 306 ----DKGSHGDGHPTNTDTPLVAWG-AGIQYP--KPASGNSHSDSVTTFVD-------KH 351
+ V +G A P P S +
Sbjct: 380 KKYIYLNKYLGDVKNIK----VIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHF 435
Query: 352 AHDMPTPYDWGLRRVERVDVN 372
+ L + +
Sbjct: 436 KPYLKHFLPKRLHFAKSDRIE 456
>emb|CAB99365.1| (AL117378) dJ131F15.2 (phosphodiesterase I/nucleotide
pyrophosphatase 1 (homologous to mouse Ly-41 antigen)
(PC1, NPPS)) [Homo sapiens]
Length = 845
Score = 279 bits (707), Expect = 2e-73
Identities = 51/321 (15%), Positives = 92/321 (27%), Gaps = 35/321 (10%)
Query: 75 DPV-PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARP 133
+P P F PP +L DG RA+ P + + K
Sbjct: 120 EPQCPAGFETPPT---LLFSLDGFRAEYLH----TWGGLLPVISKLKKCGTYTKNMRPVY 172
Query: 134 PTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSV----FNQSRHTFAFGSPDIIPIFC 189
PT++ P H +I+ G Y + + +P S + + G P +
Sbjct: 173 PTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAKY 232
Query: 190 SALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLH 249
L T+ +P + + + L+ + L+
Sbjct: 233 QGLKSGTFF-WPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLY 291
Query: 250 LLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMS---- 305
L DS+GH++ P SS + ++ VD + + L++ + I +DHGM
Sbjct: 292 LEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSC 351
Query: 306 ----DKGSHGDGHPTNTDTPLVAWG-AGIQYP--KPASGNSHSDSVTTFVD-------KH 351
+ V +G A P P S +
Sbjct: 352 KKYIYLNKYLGDVKNIK----VIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHF 407
Query: 352 AHDMPTPYDWGLRRVERVDVN 372
+ L + +
Sbjct: 408 KPYLKHFLPKRLHFAKSDRIE 428
>ref|NP_005012.1| (NM_005021) ectonucleotide pyrophosphatase/phosphodiesterase 3;
phosphodiesterase I/nucleotide pyrophosphatase 3;
phosphodiesterase-I beta; gp130RB13-6; bovine intestinal
phosphodiesterase [Homo sapiens]
gb|AAC51813.1| (AF005632) phosphodiesterase I/nucleotide pyrophosphatase beta
[Homo sapiens]
Length = 875
Score = 278 bits (705), Expect = 3e-73
Identities = 46/234 (19%), Positives = 76/234 (31%), Gaps = 12/234 (5%)
Query: 78 PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTES 137
P F PP ++L DG RA+ + P + + A PT++
Sbjct: 153 PEGFDLPP---VILFSMDGFRAEYLY----TWDTLMPNINKLKTCGIHSKYMRAMYPTKT 205
Query: 138 RPGHVAIIAGFYEDPSAVTKGWKAN---PVEFD-SVFNQSRHTFAFGSPDIIPIFCSALP 193
P H I+ G Y + + + F S Q+ + G P + L
Sbjct: 206 FPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLK 265
Query: 194 HSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGC 253
+T+ +P + S L + ++
Sbjct: 266 AATYF-WPGSEVAINGSFPSIYMPYNGSVPFEERISTLLKWLDLPKAERPRFYTMYFEEP 324
Query: 254 DSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDK 307
DS+GHA P S+ + ++VVD + L+ N + I ADHGM
Sbjct: 325 DSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQT 378
>gb|AAF56711.1| (AE003761) CG13978 gene product [Drosophila melanogaster]
Length = 475
Score = 277 bits (703), Expect = 5e-73
Identities = 62/288 (21%), Positives = 118/288 (40%), Gaps = 32/288 (11%)
Query: 296 YIFTAD-----HGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVDK 350
+++ AD H +HG G P +TPL WGAG++ + + + +
Sbjct: 200 FVYLADMDIAAHRFKPLRAHGSGSPLEVETPLFMWGAGVKRDEIDAEANFPEKPNIS--- 256
Query: 351 HAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGYMKLNEAEEVE 410
V+Q +APLMS+L+GLP P N++ +P+GY+ +++ +
Sbjct: 257 -------------------QVDQTQLAPLMSSLIGLPPPKNNLALMPVGYLNVSDEYQAV 297
Query: 411 AVVANTKQILNQ--LLRKSYIKSSNSLFFKPFKPLV--HHSFSLSQIDELISAKSYEAAM 466
A+ N Q+L+Q +L + K+ + FK L +Q D L S + AM
Sbjct: 298 ALHLNVLQLLSQAEILIGRHEKAIFYKWLPKFKELHIGVIDQYAAQFDILKSEGNLTDAM 357
Query: 467 KLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSSLSGDLSKKEH 526
+ + L+ + L Y+ Y L+ ++ Y W L L + + S +
Sbjct: 358 EFCKEYGKLAKKCLTYYNQYYQTPLIVANSMSYMIWFYCLLLQLTRL-SKKEKMQRRGFM 416
Query: 527 LSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRLI 574
+ ++ +L + ++ P + Y+ + V + +E I
Sbjct: 417 TVSTLILAMIGILLIAMMELQKVPHIAAFYLILPVGMLIMAQAERPDI 464
Score = 235 bits (596), Expect = 2e-60
Identities = 67/218 (30%), Positives = 106/218 (47%), Gaps = 9/218 (4%)
Query: 48 VLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFS---EPPAKRLVLLISDGLRADKFFE 104
+ + +H + M +I + YF+ ++ + P EPPA RLV+ ++DGLRA F
Sbjct: 4 LQALVVHILLMGAILNTYFQHTLLPNLVPQKTMRELGLEPPADRLVVFVTDGLRAATFLA 63
Query: 105 PDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPV 164
+ P L++I + QGR G+S PT +RPGH+AI AGF+EDP+A NP
Sbjct: 64 NNGSD---VPDLKDIYRQQGRIGISRTCAPTMTRPGHIAIFAGFHEDPAASLMHLCYNPG 120
Query: 165 EFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEG 224
+FD+VFN+SR+ + I+ F + E + D+W+FD+ E
Sbjct: 121 DFDTVFNRSRNMIGWAHSYIVGYFVKLSHGGAPLRFDSYMERDLPEKLTCDKWAFDKVEN 180
Query: 225 LLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRP 262
L ++E + V F++L D H +P
Sbjct: 181 FLRN---VDNVREWRNYKPAVFFVYLADMDIAAHRFKP 215
>ref|NP_445987.1| (NM_053535) ectonucleotide pyrophosphatase/phosphodiesterase 1
[Rattus norvegicus]
gb|AAK69654.1|AF340186_1 (AF340186) ecto-nucleotide pyrophosphatase/phosphodiesterase-1
[Rattus norvegicus]
Length = 906
Score = 276 bits (700), Expect = 1e-72
Identities = 55/317 (17%), Positives = 99/317 (30%), Gaps = 29/317 (9%)
Query: 76 PV-PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPP 134
P P F PP +L DG RA+ P + + P
Sbjct: 183 PQCPAEFESPPT---LLFSLDGFRAEYLH----TWGGLLPVISKLKNCGTYTKNMRPVYP 235
Query: 135 TESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSV----FNQSRHTFAFGSPDIIPIFCS 190
T++ P H +I+ G Y + + +P S + + G P +
Sbjct: 236 TKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQ 295
Query: 191 ALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHL 250
+ T+ +P + + + L+ ++ L+L
Sbjct: 296 EVRSGTYF-WPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSYERPHFYTLYL 354
Query: 251 LGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGS- 309
DS+GH+H P SS + ++ VD I + L+D D + I +DHGM GS
Sbjct: 355 EEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKDLGLDKCLNLILISDHGMEQ-GSC 413
Query: 310 ----HGDGHPTNTDTPLVAWG-AGIQYPK--PASGNSHSDSVTTFVD-------KHAHDM 355
+ + + + + V +G A P P + S + +
Sbjct: 414 KKYVYLNKYLGDVNNVKVVYGPAARLRPTEVPETYYSFNYEALAKNLSCRETNQHFRPYL 473
Query: 356 PTPYDWGLRRVERVDVN 372
L + +
Sbjct: 474 KHFLPKRLHFAKNDRIE 490
>pir||A27410 plasma cell membrane glycoprotein PC-1 - mouse
Length = 905
Score = 276 bits (699), Expect = 2e-72
Identities = 54/314 (17%), Positives = 99/314 (31%), Gaps = 28/314 (8%)
Query: 78 PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTES 137
P F PP +L DG RA+ P + + PT++
Sbjct: 186 PAEFESPPT---LLFSLDGFRAEYLH----TWGGLLPVISKLKNCGTYTKNMRPMYPTKT 238
Query: 138 RPGHVAIIAGFYEDPSAVTKGWKANPVEFDSV----FNQSRHTFAFGSPDIIPIFCSALP 193
P H +I+ G Y + + +P S + + G P + +
Sbjct: 239 FPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVK 298
Query: 194 HSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGC 253
T+ +P + + + L+ H+ L+L
Sbjct: 299 SGTYF-WPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEP 357
Query: 254 DSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGS---- 309
DS+GH+H P SS + ++ VD++ + L+D D + I +DHGM GS
Sbjct: 358 DSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQ-GSCKKY 416
Query: 310 -HGDGHPTNTDTPLVAWG-AGIQYPK--PASGNSHSDSVTTFVD-------KHAHDMPTP 358
+ + + + + V +G A P P + S + +
Sbjct: 417 VYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPF 476
Query: 359 YDWGLRRVERVDVN 372
L + +
Sbjct: 477 LPKRLHFAKSDRIE 490
>gb|AAK69653.1|AF340185_1 (AF340185) ecto-nucleotide pyrophosphatase/phosphodiesterase-1
[Rattus norvegicus]
Length = 906
Score = 276 bits (699), Expect = 2e-72
Identities = 56/317 (17%), Positives = 100/317 (30%), Gaps = 29/317 (9%)
Query: 76 PV-PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPP 134
P P F PP +L DG RA+ P + + P
Sbjct: 183 PQCPAEFESPPT---LLFSLDGFRAEYLH----TWGGLLPVISKLKNCGTYTKNMRPVYP 235
Query: 135 TESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSV----FNQSRHTFAFGSPDIIPIFCS 190
T++ P H +I+ G Y + + +P S + + G P +
Sbjct: 236 TKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQ 295
Query: 191 ALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHL 250
+ T+ +P + + + L+ ++ L+L
Sbjct: 296 EVRSGTYF-WPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSYERPHFYTLYL 354
Query: 251 LGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGS- 309
DS+GH+H P SS + ++ VD I + L+D D + I +DHGM GS
Sbjct: 355 EEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKDLGLDKCLNLILISDHGMEQ-GSC 413
Query: 310 ----HGDGHPTNTDTPLVAWG-AGIQYPK--PASGNSHSDSVTTFVD-------KHAHDM 355
+ + + + + V +G A P P + S + T +
Sbjct: 414 KKYVYLNKYLGDVNNVKVVYGPAARLRPTEVPETYYSFNYEALTKNLSCRETNQHFRPYL 473
Query: 356 PTPYDWGLRRVERVDVN 372
L + +
Sbjct: 474 KHFLPKRLHFAKNDRIE 490
>ref|NP_032839.2| (NM_008813) phosphodiesterase I/nucleotide pyrophosphatase 1; 1
ectonucleotide pyrophosphatase/phosphodiesterase 1 [Mus
musculus]
gb|AAA39893.2| (J02700) ecto-nucleotide pyrophosphatase/phosphodiesterase-1 [Mus
musculus domesticus]
Length = 905
Score = 276 bits (699), Expect = 2e-72
Identities = 54/314 (17%), Positives = 99/314 (31%), Gaps = 28/314 (8%)
Query: 78 PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTES 137
P F PP +L DG RA+ P + + PT++
Sbjct: 186 PAEFESPPT---LLFSLDGFRAEYLH----TWGGLLPVISKLKNCGTYTKNMRPMYPTKT 238
Query: 138 RPGHVAIIAGFYEDPSAVTKGWKANPVEFDSV----FNQSRHTFAFGSPDIIPIFCSALP 193
P H +I+ G Y + + +P S + + G P + +
Sbjct: 239 FPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVK 298
Query: 194 HSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGC 253
T+ +P + + + L+ H+ L+L
Sbjct: 299 SGTYF-WPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEP 357
Query: 254 DSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGS---- 309
DS+GH+H P SS + ++ VD++ + L+D D + I +DHGM GS
Sbjct: 358 DSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQ-GSCKKY 416
Query: 310 -HGDGHPTNTDTPLVAWG-AGIQYPK--PASGNSHSDSVTTFVD-------KHAHDMPTP 358
+ + + + + V +G A P P + S + +
Sbjct: 417 VYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPF 476
Query: 359 YDWGLRRVERVDVN 372
L + +
Sbjct: 477 LPKRLHFAKSDRIE 490
>gb|AAK84174.1|AF339910_1 (AF339910) ectonucleotide pyrophosphatase/phosphodiesterase 1
allotype b [Mus musculus]
Length = 906
Score = 276 bits (699), Expect = 2e-72
Identities = 54/314 (17%), Positives = 99/314 (31%), Gaps = 28/314 (8%)
Query: 78 PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTES 137
P F PP +L DG RA+ P + + PT++
Sbjct: 186 PAEFESPPT---LLFSLDGFRAEYLH----TWGGLLPVISKLKNCGTYTKNMRPMYPTKT 238
Query: 138 RPGHVAIIAGFYEDPSAVTKGWKANPVEFDSV----FNQSRHTFAFGSPDIIPIFCSALP 193
P H +I+ G Y + + +P S + + G P + +
Sbjct: 239 FPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVK 298
Query: 194 HSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGC 253
T+ +P + + + L+ H+ L+L
Sbjct: 299 SGTYF-WPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEP 357
Query: 254 DSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGS---- 309
DS+GH+H P SS + ++ VD++ + L+D D + I +DHGM GS
Sbjct: 358 DSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQ-GSCKKY 416
Query: 310 -HGDGHPTNTDTPLVAWG-AGIQYPK--PASGNSHSDSVTTFVD-------KHAHDMPTP 358
+ + + + + V +G A P P + S + +
Sbjct: 417 VYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPF 476
Query: 359 YDWGLRRVERVDVN 372
L + +
Sbjct: 477 LPKRLHFAKSDRIE 490
>gb|AAL26912.1| (AF320054) ecto-nucleotide pyrophosphatase [Rattus norvegicus]
Length = 906
Score = 274 bits (695), Expect = 4e-72
Identities = 53/317 (16%), Positives = 98/317 (30%), Gaps = 29/317 (9%)
Query: 76 PV-PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPP 134
P P F PP +L DG RA+ P + + P
Sbjct: 183 PQCPAEFESPPT---LLFSLDGFRAEYLH----TWGGLLPVISKLKNCGTYTKNMRPVYP 235
Query: 135 TESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSV----FNQSRHTFAFGSPDIIPIFCS 190
T++ P H +I+ G Y + + +P S + + G P +
Sbjct: 236 TKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQ 295
Query: 191 ALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHL 250
+ T+ +P + + + L+ ++ L+L
Sbjct: 296 EVRSGTYF-WPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSYERPHFYTLYL 354
Query: 251 LGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGS- 309
DS+GH+H P SS + ++ VD I + L+D D + I +DHGM GS
Sbjct: 355 EEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKDLGLDKCLNLILISDHGMEQ-GSC 413
Query: 310 ----HGDGHPTNTDTPLVAWGAGIQY---PKPASGNSHSDSVTTFVD-------KHAHDM 355
+ + + + + V +G + P + S + +
Sbjct: 414 KKYVYLNKYLGDVNNVKVVYGPAARLNPPEVPETYYSFNYEALAKNLSCRETNQHFRPYL 473
Query: 356 PTPYDWGLRRVERVDVN 372
L + +
Sbjct: 474 KHFLPKRLHFAKNDRIE 490
>pir||T33724 hypothetical protein - Zymomonas mobilis
gb|AAC70363.1| (AF086791) unknown [Zymomonas mobilis]
Length = 429
Score = 274 bits (694), Expect = 6e-72
Identities = 50/279 (17%), Positives = 95/279 (33%), Gaps = 25/279 (8%)
Query: 39 LKRRETWLVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLR 98
LK+R+ W + G+ ++ + + + V + P L+L+ DG R
Sbjct: 8 LKKRKPW--ISGIL--SLLLGCAGLSVVHSDAIAATAHVTAQSKTP----LILISIDGFR 59
Query: 99 ADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKG 158
AD + P L ++ +N V H P+ + P H ++ G Y D +
Sbjct: 60 ADYI------KRGLTPNLVSLAENGSYAKVMHPSFPSITFPNHYTLVTGLYPDHHGIVGN 113
Query: 159 WKANP-VEFDSVFNQSRH-------TFAFGSPDIIPIFCSALPHSTWNSYPHEYEDFATD 210
+ + DS F S H + G P + + +T +P D
Sbjct: 114 NMDDAHITPDSHFKMSDHQAATDRRWWDEGEPLWVTAEKQGVVSATMF-WPGSEADIEGV 172
Query: 211 ASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNN 270
+ L + + L+ D GH + P S +N
Sbjct: 173 RPEMWRQFDSHVPFSERVDQVFSWLAYPKKKRPQFITLYFENVDHAGHLYGPDSQEVNDN 232
Query: 271 VKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGS 309
+ +D+ ++ L+ + + + +DHGM+ S
Sbjct: 233 LVKIDQTIGQLVQGLKQRGI--KANLVIVSDHGMAATSS 269
>sp|P06802|PC1_MOUSE Ectonucleotide pyrophosphatase/phosphodiesterase 1 (Plasma-cell
membrane glycoprotein PC-1) [Includes: Alkaline
phosphodiesterase I ; Nucleotide pyrophosphatase
(NPPASE)]
Length = 871
Score = 274 bits (694), Expect = 6e-72
Identities = 52/313 (16%), Positives = 97/313 (30%), Gaps = 26/313 (8%)
Query: 78 PPRFSEPPAKRLVLLISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTES 137
P F PP +L DG RA+ P + + PT++
Sbjct: 152 PAEFESPPT---LLFSLDGFRAEYLH----TWGGLLPVISKLKNCGTYTKNMRPMYPTKT 204
Query: 138 RPGHVAIIAGFYEDPSAVTKGWKANPVEFDSV----FNQSRHTFAFGSPDIIPIFCSALP 193
P H +I+ G Y + + +P S + + G P + +
Sbjct: 205 FPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVK 264
Query: 194 HSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGC 253
T+ +P + + + L+ H+ L+L
Sbjct: 265 SGTYF-WPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEP 323
Query: 254 DSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKG----S 309
DS+GH+H P SS + ++ VD++ + L+D D + I +DHGM
Sbjct: 324 DSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYV 383
Query: 310 HGDGHPTNTDTPLVAWG-AGIQYPK--PASGNSHSDSVTTFVD-------KHAHDMPTPY 359
+ + + + + V +G A P P + S + +
Sbjct: 384 YLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFL 443
Query: 360 DWGLRRVERVDVN 372
L + +
Sbjct: 444 PKRLHFAKSDRIE 456
>ref|NP_491098.1| (NM_058697) M01B12.2.p [Caenorhabditis elegans]
pir||T33168 hypothetical protein M01B12.2 - Caenorhabditis elegans
Length = 559
Score = 198 bits (499), Expect = 4e-49
Identities = 85/401 (21%), Positives = 144/401 (35%), Gaps = 56/401 (13%)
Query: 513 CYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYR 572
K V G + + VL ++ + + M + + +
Sbjct: 142 NKVLSVEVFVKPFLGFV---GFSITICIFVLTFMDRAFLAAVFVLLMALPQFYS----HP 194
Query: 573 LIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFLIAGVVASILLH 632
++ K I A + L + S I L
Sbjct: 195 IVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCILS-----------PIITAFLCHRLS 243
Query: 633 FSIPWRSGIPVFVCISCWFLSVFTLMPAE---IPDNNNLVSPFLGANDTDI--------- 680
+ + + ++ L+ ++
Sbjct: 244 RRSCLTRIQRMLELMIYVQSATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSLQPP 303
Query: 681 -----FGWCVICDGVFVDKAS-------NAESRIAFVTSVHKLVSCRYEAVFYSALAVVL 728
W I V + + L+S YE++F V+L
Sbjct: 304 SIARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFLVLL 363
Query: 729 MAWILFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMVLFNVAFFG 788
++ FE H S V+ L ++T S Y++L + + F++ FG
Sbjct: 364 TLFVRFEFG--HLSDVELLQLKVDST-----KISTGEYVELRRTVVCVSFVL---CPLFG 413
Query: 789 TGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKLVR--VPRL 846
TGNFASI SF S++ FI++FSPF MA LLI KL IP +LV AF++I + + + RL
Sbjct: 414 TGNFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQESIQRL 473
Query: 847 GCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVS 887
C+ L+ F+D M++ FF +++ GSW++IG SIS F +
Sbjct: 474 CCFSLI--FTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSM 512
Score = 193 bits (487), Expect = 1e-47
Identities = 38/240 (15%), Positives = 81/240 (32%), Gaps = 18/240 (7%)
Query: 450 LSQIDELISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALH 509
+ + +L + + A L D +L E + ++ YD ML ++ + W+ ++
Sbjct: 5 RTTLAQLGRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIALVVSF 64
Query: 510 VLQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFS 569
+ S + L HL + C L+ + + + +++ +
Sbjct: 65 LHNSTSKENLSLLVPHHLFIIPLACSLLFTAYCSLSMTQTIYIILPIYLISILENHSKLT 124
Query: 570 EYRLIRGLWKYLRERR--------ADYFIKLLFAAAVAVVIVELLVHSFTERK-LYTWFF 620
+ IR K L + + F+K + + + V +F +R L F
Sbjct: 125 QR--IREHVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAVFV 182
Query: 621 LIAGVVASILLHFSIPWRSGIPVFVCISCWFLSVFTLMPAEIPDNN---NLVSPFLGAND 677
L+ + W C L +F +PA + ++SP + A
Sbjct: 183 LLMALPQFYSHPIVSYWSKT----WLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFL 238
CPU time: 296.61 user secs. 3.39 sys. secs 300.00 total secs.
Database: nr
Posted date: Apr 21, 2002 2:19 PM
Number of letters in database: 277,845,442
Number of sequences in database: 887,402
Lambda K H
0.316 0.178 0.489
Gapped
Lambda K H
0.270 0.0623 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 683428609
Number of Sequences: 887402
Number of extensions: 41574846
Number of successful extensions: 178932
Number of sequences better than 10.0: 1121
Number of HSP's better than 10.0 without gapping: 160
Number of HSP's successfully gapped in prelim test: 981
Number of HSP's that attempted gapping in prelim test: 176565
Number of HSP's gapped (non-prelim): 2534
length of query: 921
length of database: 277,845,442
effective HSP length: 55
effective length of query: 866
effective length of database: 229,038,332
effective search space: 198347195512
effective search space used: 198347195512
T: 11
A: 40
X1: 15 ( 6.8 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.8 bits)
S2: 78 (34.4 bits)
