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GPI Anchor Biosynthesis Report: NP_012756.1 (PIG-N family, Saccharomyces cerevisiae)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query=
         (919 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Converged !!!


Results of PSI-Blast iteration 4

Distribution of 52 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)

ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class ... 1027 0.0
ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; ... 1046 0.0
ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class ... 1011 0.0
pir||T40715 hypothetical protein SPBC839.08c - fission yeast (S... 910 0.0
pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragme... 878 0.0
dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N sh... 852 0.0
gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinosito... 846 0.0
ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan... 809 0.0
gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melano... 799 0.0
gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melano... 787 0.0
gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caeno... 781 0.0
gb|AAF54657.1| (AE003692) CG6790 gene product [Drosophila melano... 644 0.0
ref|XP_082200.1| (XM_082200) CG6790 [Drosophila melanogaster] 568 e-160
pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast (... 542 e-152
dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [M... 516 e-145
gb|AAF54658.1| (AE003692) CG5342 gene product [Drosophila melano... 445 e-123
dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:13516... 403 e-111
ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans] 388 e-106
ref|NP_491098.1| (NM_058697) M01B12.2.p [Caenorhabditis elegans]... 387 e-106
pir||T02245 hypothetical protein P1.11659_3 - human >gi|2984587|... 378 e-103
ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class ... 347 4e-94
gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarr... 323 7e-87
ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thalia... 313 9e-84
ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]... 306 1e-81
gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melano... 298 2e-79
ref|NP_495820.1| (NM_063419) Yeast YJ10 like [Caenorhabditis ele... 297 5e-79
gb|AAF56711.1| (AE003761) CG13978 gene product [Drosophila melan... 289 1e-76
ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) ... 283 8e-75
gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melan... 274 6e-72
ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thalia... 263 8e-69
ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like pr... 257 5e-67
dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like prote... 257 5e-67
gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophos... 253 1e-65
ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like p... 248 3e-64
ref|NP_476445.1| (NM_057104) phosphodiesterase I/nucleotide pyro... 244 6e-63
ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like p... 242 2e-62
pir||T03293 nucleotide pyrophosphatase homolog - rice >gi|818849... 242 2e-62
gb|AAH03264.1|AAH03264 (BC003264) ectonucleotide pyrophosphatase... 242 2e-62
ref|NP_056559.1| (NM_015744) phosphodiesterase I/nucleotide pyro... 242 3e-62
dbj|BAA08260.1| (D45421) phosphodiesterase I alpha [Homo sapiens] 239 2e-61
ref|NP_006200.1| (NM_006209) ectonucleotide pyrophosphatase/phos... 238 2e-61
pir||T33724 hypothetical protein - Zymomonas mobilis >gi|3089614... 235 3e-60
ref|NP_299876.1| (NC_002488) phosphodiesterase-nucleotide pyroph... 234 5e-60
dbj|BAA87261.1| (AB027957) Hypothetical protein [Schizosaccharom... 232 2e-59
pir||T40657 probable phophodiesterase-nucleotide pyrophosp hatas... 227 5e-58
ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo ... 224 4e-57
ref|NP_116023.1| (NM_032634) hypothetical protein MGC3079 [Homo ... 217 6e-55
ref|NP_055751.1| (NM_014936) ectonucleotide pyrophosphatase/phos... 209 2e-52
Alignments
>ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class N [Mus musculus]
 dbj|BAA82619.1| (AB030279) phosphatidylinositolglycan class N [Mus musculus]
          Length = 931

 Score = 1027 bits (2629), Expect = 0.0
 Identities = 335/935 (35%), Positives = 514/935 (54%), Gaps = 55/935 (5%)

Query: 7   TTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTFD 66
               A+G+L H  +  SIFDIYF SPLVHGM+P  +   PPAKRL L V DGLRADT ++
Sbjct: 2   LLFFALGLLIHFVFFVSIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYE 61

Query: 67  KVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGW 126
                +       APFIR+++M+  ++G+SHTR+PTESRPGHVA+IAGFYEDVSAV KGW
Sbjct: 62  -----LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 127 KSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDF-TQSSIELD 185
           K NPV FDS FN+S +T+S+GSPDILPMF  GAS  + V T+ YD   EDF    + +LD
Sbjct: 117 KENPVEFDSLFNESKYTWSWGSPDILPMFAKGAS-GDHVYTYSYDAQREDFGAHDATKLD 175

Query: 186 AFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYID 245
            +VF  +   F  +  N +L  ++ ++  VFFLHLLG DT GH++RP S EY DN+K +D
Sbjct: 176 TWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIKKVD 235

Query: 246 DQIPILIDKVNKFFADD-KTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPV- 303
           D +  ++     F+ DD KTAFIFT+DHGM+ +GSHG GHP+ T TP V WGAG+  P  
Sbjct: 236 DGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQN 295

Query: 304 HNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESD 363
            +     D + + W L + KR DV QADIA LM+ LIGV +P NSVG LP+ Y++     
Sbjct: 296 VSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLF 355

Query: 364 KLAALYNNARSILEQYLVKQDEVIDS--QFFYKEYFKFVEKSHSHYLEEIETLIQRISEG 421
           K  +++ NA  ILEQ+ VK  +  ++   F +  +    +      L +  + I++    
Sbjct: 356 KAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQ---- 411

Query: 422 ENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFILE 481
                 E ++L EEL+ + L GL Y  TY+  F+   V  GFVGW+ ++ ++ +KS    
Sbjct: 412 --EKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSNI 469

Query: 482 NV---IDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNRSVL 538
                 + +K   L    F + G+L+   L  Q  P+ +Y+Y L P+  W  +     V+
Sbjct: 470 PKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVI 529

Query: 539 RSGIKEFFKGTSPWKRVLITISIISV-YEGIVYGFFHRWTFTLITNILAFYPFICGV--R 595
           +  ++     T P    +  + + ++  E +V  FF+R+  T    + A +PF+  +  R
Sbjct: 530 QDLVESLL--TFPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWTR 587

Query: 596 ELSVNILWIITSVLLSTFTLFDAV-KIEDLNQIHLAGLLIILSAFYALYKIHSR----IN 650
                + W   S+LL+ F L   V +  +L+ +  AG L++L +   +  +  R    + 
Sbjct: 588 AKITFLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKLVK 647

Query: 651 SYTRAIFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRK 710
                +    +S V +M  V + +  SL  ++GLP  +Q+  W     SL          
Sbjct: 648 GELLVLLLQMLSTVLSMY-VVYSTHHSLLKKEGLPLMNQIVSWATLASSLVA-----PLL 701

Query: 711 PNNDYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEM-------- 762
            +     RL  I L+   ++++L+  +E+LF  + +  M  WI++E +  +         
Sbjct: 702 SSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQETLQQPGVSCKQK 761

Query: 763 ----KTQKDENWLQ-------VLRVSVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPI 811
               +   D +  Q        +R +    F L  AFFGTGN+ASI+SF L SV   L +
Sbjct: 762 LTSIQFTCDTDIAQFRQLCPDDIRRAFFLVFFLLTAFFGTGNIASINSFDLASVYCFLTV 821

Query: 812 FDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIISMSDILSLNFFYLLRT 871
           F PF+MGAL+M K++IP+ L+      + +        +  +++ +SDI++L+FF+L++ 
Sbjct: 822 FSPFMMGALMMWKILIPFVLVMCAFEAVQITTQLSSKGLFLVVLIISDIMALHFFFLVKD 881

Query: 872 EGSWLDIGITISNYCLAILSSLFMLILEVLGHVLL 906
            GSWLDIG +IS+Y + +  ++F++ L  L  +L 
Sbjct: 882 SGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLT 916
>ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; Mcd4p [Saccharomyces
           cerevisiae]
 sp|P36051|YKQ5_YEAST HYPOTHETICAL 105.7 KD PROTEIN IN TPK3-PIR1 INTERGENIC REGION
 pir||S37786 hypothetical protein YKL165c - yeast (Saccharomyces cerevisiae)
 emb|CAA81489.1| (Z26877) unknown [Saccharomyces cerevisiae]
 emb|CAA82007.1| (Z28165) ORF YKL165c [Saccharomyces cerevisiae]
 prf||2118404A ORF [Saccharomyces cerevisiae]
          Length = 919

 Score = 1046 bits (2676), Expect = 0.0
 Identities = 919/919 (100%), Positives = 919/919 (100%)

Query: 1   MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLR 60
           MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLR
Sbjct: 1   MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLR 60

Query: 61  ADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVS 120
           ADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVS
Sbjct: 61  ADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVS 120

Query: 121 AVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQS 180
           AVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQS
Sbjct: 121 AVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQS 180

Query: 181 SIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDN 240
           SIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDN
Sbjct: 181 SIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDN 240

Query: 241 VKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLN 300
           VKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLN
Sbjct: 241 VKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLN 300

Query: 301 KPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGK 360
           KPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGK
Sbjct: 301 KPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGK 360

Query: 361 ESDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISE 420
           ESDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISE
Sbjct: 361 ESDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISE 420

Query: 421 GENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFIL 480
           GENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFIL
Sbjct: 421 GENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFIL 480

Query: 481 ENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNRSVLRS 540
           ENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNRSVLRS
Sbjct: 481 ENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNRSVLRS 540

Query: 541 GIKEFFKGTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILAFYPFICGVRELSVN 600
           GIKEFFKGTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILAFYPFICGVRELSVN
Sbjct: 541 GIKEFFKGTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILAFYPFICGVRELSVN 600

Query: 601 ILWIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAFYALYKIHSRINSYTRAIFAIQ 660
           ILWIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAFYALYKIHSRINSYTRAIFAIQ
Sbjct: 601 ILWIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAFYALYKIHSRINSYTRAIFAIQ 660

Query: 661 ISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRKPNNDYKVRLL 720
           ISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRKPNNDYKVRLL
Sbjct: 661 ISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRKPNNDYKVRLL 720

Query: 721 IIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEMKTQKDENWLQVLRVSVIG 780
           IIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEMKTQKDENWLQVLRVSVIG
Sbjct: 721 IIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEMKTQKDENWLQVLRVSVIG 780

Query: 781 FFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILN 840
           FFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILN
Sbjct: 781 FFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILN 840

Query: 841 LKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLDIGITISNYCLAILSSLFMLILEV 900
           LKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLDIGITISNYCLAILSSLFMLILEV
Sbjct: 841 LKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLDIGITISNYCLAILSSLFMLILEV 900

Query: 901 LGHVLLKNVIIQDKTKKTQ 919
           LGHVLLKNVIIQDKTKKTQ
Sbjct: 901 LGHVLLKNVIIQDKTKKTQ 919
>ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class N; endoplasmic
           reticulum membrane protein [Homo sapiens]
 gb|AAD11432.1| (AF109219) Mcd4p homolog [Homo sapiens]
          Length = 931

 Score = 1011 bits (2588), Expect = 0.0
 Identities = 344/934 (36%), Positives = 526/934 (55%), Gaps = 53/934 (5%)

Query: 7   TTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTFD 66
                +G+L H  +  SIFDIYF SPLVHGM+P  +   PPA+RL L V DGLRAD  ++
Sbjct: 2   LLFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPARRLVLFVADGLRADALYE 61

Query: 67  KVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGW 126
                +       APFIR+++M+  ++GISHTR+PTESRPGHVA+IAGFYEDVSAV KGW
Sbjct: 62  -----LDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 127 KSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDF-TQSSIELD 185
           K NPV FDS FN+S +T+S+GSPDILPMF  GAS  + V T+ YD   EDF  Q + +LD
Sbjct: 117 KENPVEFDSLFNESKYTWSWGSPDILPMFAKGAS-GDHVYTYSYDAKREDFGAQDATKLD 175

Query: 186 AFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYID 245
            +VF ++   FH++  N +L  +I ++  VFFLHLLG DT GH++RP S +Y  N+K +D
Sbjct: 176 TWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIKKVD 235

Query: 246 DQIPILIDKVNKFFADD-KTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPV- 303
           D +  ++   N F+ +D KT FIFT+DHGM+ +GSHG GHP+ T TPLV WGAG+  P  
Sbjct: 236 DGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKYPQR 295

Query: 304 HNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESD 363
            +     D + + W L + KR DV QADIA LM+ LIGV +P NSVG LP+ Y++  +  
Sbjct: 296 VSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILPVDYLNNTDLF 355

Query: 364 KLAALYNNARSILEQYLVKQDEVIDS--QFFYKEYFKFVEKSHSHYLEEIETLIQRISEG 421
           K  +++ NA  ILEQ+ VK  +  +    F +  +    +    + L +  + I+     
Sbjct: 356 KAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILRKARSYIKHRK-- 413

Query: 422 ENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFI-- 479
                 E ++L +EL+ + L+GL Y  TY+  F+   V  GFVGWI ++ ++ +KS    
Sbjct: 414 ----FDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLIIKSHSNL 469

Query: 480 LENVIDD-QKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNRSVL 538
           ++ V  + +K S L    F +IGIL+ + L  Q  P+ +Y+Y L PL  W  +     V+
Sbjct: 470 IKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWYAVLREFQVI 529

Query: 539 RSGIKEFFKGTSPWKRVLITISIISV-YEGIVYGFFHRWTFTLITNILAFYPFICGV--R 595
           +  +      T P    +  +   ++  E +V  FF+R+  T      A +PF+  +  R
Sbjct: 530 QDLVVSVL--TYPLSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAFAAWPFLTRLWTR 587

Query: 596 ELSVNILWIITSVLLSTFTLFDAV-KIEDLNQIHLAGLLIILSAFYALYKIHSRINSYTR 654
               ++ W   S+LL+ F L   V +  D++ +  AGLL++L +   +  +  R +S+ +
Sbjct: 588 AKMTSLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAGLLVLLLSLCVVTSLMKRKDSFIK 647

Query: 655 A---IFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRKP 711
               +  +Q+      + V + +  SL  +QGLP  +Q+  W     SL V         
Sbjct: 648 EELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQIISWATLASSLVV-----PLLS 702

Query: 712 NNDYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEMK-------- 763
           +     RL  I L+   ++++L+  +E+LF  + +  M  WI IE +  +          
Sbjct: 703 SPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIEQETLQQSGVCCKQKL 762

Query: 764 -----------TQKDENWLQVLRVSVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPIF 812
                      TQ  + +L  +R +    F L  AFFGTGN+ASI+SF L SV   L +F
Sbjct: 763 TSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIASINSFDLASVYCFLTVF 822

Query: 813 DPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIISMSDILSLNFFYLLRTE 872
            PF+MGAL+M K++IP+ L+      + L       ++  +++ +SDI++L+FF+L++  
Sbjct: 823 SPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLVISDIMALHFFFLVKDY 882

Query: 873 GSWLDIGITISNYCLAILSSLFMLILEVLGHVLL 906
           GSWLDIG +IS+Y + +  ++F++ L  L  +L 
Sbjct: 883 GSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLT 916
>pir||T40715 hypothetical protein SPBC839.08c - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA17011.1| (AL021816) hypothetical protein [Schizosaccharomyces pombe]
 emb|CAB46701.1| (AL096796) hypothetical protein [Schizosaccharomyces pombe]
          Length = 935

 Score =  910 bits (2328), Expect = 0.0
 Identities = 389/932 (41%), Positives = 560/932 (59%), Gaps = 41/932 (4%)

Query: 9   LLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTFDKV 68
           LL +G+LFH+ +L SIFDIYF++PL+HGM    S    PAKRLFLIVGDGLR D      
Sbjct: 5   LLLLGILFHVVFLKSIFDIYFVTPLIHGM-KQYSAGEAPAKRLFLIVGDGLRPDKLLQPH 63

Query: 69  THPVSGKTE-FLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGWK 127
           +  V G+ + + APF+RS++ NN T+G+SHTR+PTESRPGHVA+IAGFYEDVSAVTKGWK
Sbjct: 64  SEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWK 123

Query: 128 SNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQSSIELDAF 187
            NPVNFDS FNQS HTYSFGS DILPMF +GASDP++VDT+MY    EDF+ + I LD +
Sbjct: 124 KNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVLDEW 183

Query: 188 VFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQ 247
           VF  LD+L   S  +  L   + +D  VFFLHLLG DT GH+  P S EY +N++YID +
Sbjct: 184 VFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGK 243

Query: 248 IPILIDKVNKFFADDK-TAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHNP 306
           I  L+DK+N ++ +D  ++++FTADHGMS FGSHGDG+ +NTRTP++AWGAG+  P H  
Sbjct: 244 IQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEK 303

Query: 307 FPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESDKLA 366
               D Y+  W L+ IKR D++QADIA+LMSYL+G+N+P NSVG++P+ Y+D     K  
Sbjct: 304 NYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRKAE 363

Query: 367 ALYNNARSILEQYLVKQDEVIDSQFFYKEY---FKFVEKSHSHYLEEIETLIQRISEGEN 423
               NA  I EQY +K      +  F++ Y     + E   S       ++I  I  GE 
Sbjct: 364 VALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASF----YNSVIADIESGEY 419

Query: 424 YLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFILENV 483
              + AI       Q  L GL YL  Y+W  +R+IV FG++ WI +  I F+ S  +E  
Sbjct: 420 ---EIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGY-VICFVFSLNIEPS 475

Query: 484 IDDQKASPLSHAVFGSIGILLNWILFY-QHSPFNFYMYLLFPLYFWSYIFTNRSVLRSGI 542
               K   +   V  +I  LL  I FY Q SP  +Y Y LFP  F   I +     + G 
Sbjct: 476 SKIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGF 535

Query: 543 KEFFK------GTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILAFYPFICG--- 593
           K F        G S  K + I++ I+ + + IVY +FHR  F++I   LA +P++     
Sbjct: 536 KNFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADY 595

Query: 594 -VRELSVNILWIITSVLLSTFTLFDAVKIEDLNQIHLAGL-LIILSAFYALYKIHSRIN- 650
                ++++ W + + LL  FT+    K E L  I   G  + +   FY LY+ +     
Sbjct: 596 AFSHKTISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQY 655

Query: 651 --SYTRAIFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHY 708
             + T     +Q+ ++ A + VT +   SLQ    +P   ++  + +F  S +++P  H 
Sbjct: 656 SSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITS-YIIPSHHI 714

Query: 709 RKPNNDYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIK-------- 760
           R   + +  RL I++LTF+P+  +L+ISFE+LFY +    +  W+E+E +++        
Sbjct: 715 RSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKYTEQLHP 774

Query: 761 EMKTQKDENW---LQVLRVSVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLM 817
           E   +KD  +   L  +R+S+  +  + VAFFGTGNVAS+S+F+L+SV R +P+F+P   
Sbjct: 775 EYSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQ 834

Query: 818 GALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLD 877
           GALLM  +++P+  LS   GI+N +L         L + M+DI+++NFFYL++ EGSW D
Sbjct: 835 GALLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYLVKDEGSWKD 894

Query: 878 IGITISNYCLAILSSLFMLILEVLGHVLLKNV 909
           IG++IS++C++    LF+  LE    +L KN+
Sbjct: 895 IGVSISHFCISNFLILFITALEHASAILCKNI 926
>pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragment)
 emb|CAB70839.1| (AL137607) hypothetical protein [Homo sapiens]
          Length = 825

 Score =  878 bits (2246), Expect = 0.0
 Identities = 286/824 (34%), Positives = 451/824 (54%), Gaps = 48/824 (5%)

Query: 117 EDVSAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFED 176
           EDVSAV KGWK NPV FDS FN+S +T+S+GSPDILPMF  GAS  + V T+ YD   ED
Sbjct: 1   EDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGAS-GDHVYTYSYDAKRED 59

Query: 177 F-TQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSA 235
           F  Q + +LD +VF ++   FH++  N +L  +I ++  VFFLHLLG DT GH++RP S 
Sbjct: 60  FGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSR 119

Query: 236 EYYDNVKYIDDQIPILIDKVNKFFADD-KTAFIFTADHGMSAFGSHGDGHPNNTRTPLVA 294
           +Y  N+K +DD +  ++   N F+ +D KT FIFT+DHGM+ +GSHG GHP+ T TPLV 
Sbjct: 120 DYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVT 179

Query: 295 WGAGLNKPV-HNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELP 353
           WGAG+  P   +     D + + W L + KR DV QADIA LM+ LIGV +P NSVG LP
Sbjct: 180 WGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILP 239

Query: 354 IAYIDGKESDKLAALYNNARSILEQYLVKQDEVIDS--QFFYKEYFKFVEKSHSHYLEEI 411
           + Y++  +  K  +++ NA  ILEQ+ VK  +  +    F +  +    +    + L + 
Sbjct: 240 VDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILRKA 299

Query: 412 ETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSF 471
            + I+           E ++L +EL+ + L+GL Y  TY+  F+   V  GFVGWI ++ 
Sbjct: 300 RSYIKHRK------FDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYAS 353

Query: 472 IIFLKSFI--LENVIDD-QKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFW 528
           ++ +KS    ++ V  + +K S L    F +IGIL+ + L  Q  P+ +Y+Y L PL  W
Sbjct: 354 LLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIW 413

Query: 529 SYIFTNRSVLRSGIKEFFKGTSPWKRVLITISIISV-YEGIVYGFFHRWTFTLITNILAF 587
             +     V++  +      T P    +  +   ++  E +V  FF+R+  T      A 
Sbjct: 414 YAVLREFQVIQDLVVSVL--TYPLSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAFAA 471

Query: 588 YPFICGV--RELSVNILWIITSVLLSTFTLFDAV-KIEDLNQIHLAGLLIILSAFYALYK 644
           +PF+  +  R    ++ W   S+LL+ F L   V +  D++ +  AGLL++L +   +  
Sbjct: 472 WPFLTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAGLLVLLLSLCVVTS 531

Query: 645 IHSRINSYTRA---IFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLF 701
           +  R +S+ +    +  +Q+      + V + +  SL  +QGLP  +Q+  W     SL 
Sbjct: 532 LMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQIISWATLASSLV 591

Query: 702 VMPILHYRKPNNDYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKE 761
           V         +     RL  I L+   ++++L+  +E+LF  + +  M  WI IE +  +
Sbjct: 592 V-----PLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIEQETLQ 646

Query: 762 MK-------------------TQKDENWLQVLRVSVIGFFLLQVAFFGTGNVASISSFSL 802
                                TQ  + +L  +R +    F L  AFFGTGN+ASI+SF L
Sbjct: 647 QSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIASINSFDL 706

Query: 803 ESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIISMSDILS 862
            SV   L +F PF+MGAL+M K++IP+ L+      + L       ++  +++ +SDI++
Sbjct: 707 ASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLVISDIMA 766

Query: 863 LNFFYLLRTEGSWLDIGITISNYCLAILSSLFMLILEVLGHVLL 906
           L+FF+L++  GSWLDIG +IS+Y + +  ++F++ L  L  +L 
Sbjct: 767 LHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLT 810
>dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N short form [Mus
           musculus]
          Length = 798

 Score =  852 bits (2178), Expect = 0.0
 Identities = 286/811 (35%), Positives = 434/811 (53%), Gaps = 55/811 (6%)

Query: 7   TTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTFD 66
               A+G+L H  +  SIFDIYF SPLVHGM+P  +   PPAKRL L V DGLRADT ++
Sbjct: 2   LLFFALGLLIHFVFFVSIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYE 61

Query: 67  KVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGW 126
                +       APFIR+++M+  ++G+SHTR+PTESRPGHVA+IAGFYEDVSAV KGW
Sbjct: 62  -----LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 127 KSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDF-TQSSIELD 185
           K NPV FDS FN+S +T+S+GSPDILPMF  GAS  + V T+ YD   EDF    + +LD
Sbjct: 117 KENPVEFDSLFNESKYTWSWGSPDILPMFAKGAS-GDHVYTYSYDAQREDFGAHDATKLD 175

Query: 186 AFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYID 245
            +VF  +   F  +  N +L  ++ ++  VFFLHLLG DT GH++RP S EY DN+K +D
Sbjct: 176 TWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIKKVD 235

Query: 246 DQIPILIDKVNKFFADD-KTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPV- 303
           D +  ++     F+ DD KTAFIFT+DHGM+ +GSHG GHP+ T TP V WGAG+  P  
Sbjct: 236 DGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQN 295

Query: 304 HNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESD 363
            +     D + + W L + KR DV QADIA LM+ LIGV +P NSVG LP+ Y++     
Sbjct: 296 VSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLF 355

Query: 364 KLAALYNNARSILEQYLVKQDEVIDS--QFFYKEYFKFVEKSHSHYLEEIETLIQRISEG 421
           K  +++ NA  ILEQ+ VK  +  ++   F +  +    +      L +  + I++    
Sbjct: 356 KAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQ---- 411

Query: 422 ENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFILE 481
                 E ++L EEL+ + L GL Y  TY+  F+   V  GFVGW+ ++ ++ +KS    
Sbjct: 412 --EKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSNI 469

Query: 482 NV---IDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNRSVL 538
                 + +K   L    F + G+L+   L  Q  P+ +Y+Y L P+  W  +     V+
Sbjct: 470 PKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVI 529

Query: 539 RSGIKEFFKGTSPWKRVLITISIISV-YEGIVYGFFHRWTFTLITNILAFYPFICGV--R 595
           +  ++     T P    +  + + ++  E +V  FF+R+  T    + A +PF+  +  R
Sbjct: 530 QDLVESLL--TFPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWTR 587

Query: 596 ELSVNILWIITSVLLSTFTLFDAV-KIEDLNQIHLAGLLIILSAFYALYKIHSR----IN 650
                + W   S+LL+ F L   V +  +L+ +  AG L++L +   +  +  R    + 
Sbjct: 588 AKITFLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKLVK 647

Query: 651 SYTRAIFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRK 710
                +    +S V +M  V + +  SL  ++GLP  +Q+  W     SL          
Sbjct: 648 GELLVLLLQMLSTVLSMY-VVYSTHHSLLKKEGLPLMNQIVSWATLASSLVA-----PLL 701

Query: 711 PNNDYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEM-------- 762
            +     RL  I L+   ++++L+  +E+LF  + +  M  WI++E +  +         
Sbjct: 702 SSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQETLQQPGVSCKQK 761

Query: 763 ----KTQKDENWLQ-------VLRVSVIGFF 782
               +   D +  Q        +R +   FF
Sbjct: 762 LTSIQFTCDTDIAQFRQLCPDDIRRAFFLFF 792
>gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinositol glycan, class N [Mus
           musculus]
          Length = 826

 Score =  846 bits (2163), Expect = 0.0
 Identities = 285/817 (34%), Positives = 435/817 (52%), Gaps = 55/817 (6%)

Query: 7   TTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTFD 66
               A+G+L H  +  SIFDIYF SPLVHGM+P  +   PPAKRL L V DGLRADT ++
Sbjct: 2   LLFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYE 61

Query: 67  KVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGW 126
                +       APFIR+++++  ++G+SHTR+PTESRPGHVA+IAGFYEDVSAV KGW
Sbjct: 62  -----LDEDGNSRAPFIRNVIIHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 127 KSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDF-TQSSIELD 185
           K NPV FDS FN+S +T+S+GSPDILPMF  GAS  + V T+ YD   EDF    + +LD
Sbjct: 117 KENPVEFDSLFNESKYTWSWGSPDILPMFAKGAS-GDHVYTYSYDAQREDFGAHDATKLD 175

Query: 186 AFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYID 245
            +VF  +   F  +  N +L  ++ ++  VFFLHLLG DT GH++RP S EY DN+K +D
Sbjct: 176 TWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVD 235

Query: 246 DQIPILIDKVNKFFADD-KTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPV- 303
           D +  ++     F+ DD KTAFIFT+DHGM+ +GSHG GHP+ T TP V WGAG+  P  
Sbjct: 236 DGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQN 295

Query: 304 HNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESD 363
            +     D + + W L + KR DV QADIA LM+ LIGV +P NSVG LP+ Y++     
Sbjct: 296 VSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLF 355

Query: 364 KLAALYNNARSILEQYLVKQDEVIDS--QFFYKEYFKFVEKSHSHYLEEIETLIQRISEG 421
           K  +++ NA  ILEQ+ VK  +  ++   F +  +    +      L +  + I++    
Sbjct: 356 KAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQ---- 411

Query: 422 ENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFILE 481
                 E ++L EEL+ + L GL Y  TY+  F+   V  GFVGW+ ++ ++ +KS    
Sbjct: 412 --EKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSNI 469

Query: 482 NV---IDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNRSVL 538
                 + +K   L    F + G+L+   L  Q  P+ +Y+Y L P+  W  +     V+
Sbjct: 470 PKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVI 529

Query: 539 RSGIKEFFKGTSPWKRVLITISIISV-YEGIVYGFFHRWTFTLITNILAFYPFICGV--R 595
           +  ++     T P    +  + + ++  E +V  FF+R+  T    + A +PF+  +  R
Sbjct: 530 QDLVESLL--TFPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWTR 587

Query: 596 ELSVNILWIITSVLLSTFTLFDAV-KIEDLNQIHLAGLLIILSAFYALYKIHSR----IN 650
                + W   S+LL+ F L   V +  +L+ +  AG L++L +   +  +  R    + 
Sbjct: 588 AKITFLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKLVK 647

Query: 651 SYTRAIFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRK 710
                +    +S V +M  V + +  SL  ++GLP  +Q+  W     SL          
Sbjct: 648 GELLVLLLQMLSTVLSMY-VVYSTHHSLLKKEGLPLMNQIVSWATLASSLVA-----PLL 701

Query: 711 PNNDYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEM-------- 762
            +     RL  I L+   ++++L+  +E+LF  + +  M  WI++E +  +         
Sbjct: 702 SSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQETLQQPGVSCKQK 761

Query: 763 ----KTQKDENWLQ-------VLRVSVIGFFLLQVAF 788
               +   D +  Q        +R +     L+   F
Sbjct: 762 LTSIQFTCDTDIAQFRQLCPDDIRRAFFLILLIFPVF 798
>ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
 gb|AAF24617.1|AC010870_10 (AC010870) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
          Length = 921

 Score =  809 bits (2069), Expect = 0.0
 Identities = 298/943 (31%), Positives = 453/943 (47%), Gaps = 102/943 (10%)

Query: 2   WNKTRTTLL-AVGVLFHLFYLWSIFDIYFISPLVHGMSPYQST-PTPPAKRLFLIVGDGL 59
           W K R T L  +GV  H  Y+ SIFDIYF +P+VHGM P       PPAKRL L++ DGL
Sbjct: 38  WLKRRETWLVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGL 97

Query: 60  RADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDV 119
           RAD  F+        + ++ APF+R+++ N   +G+SH R PTESRPGHVA+IAGFYED 
Sbjct: 98  RADKFFEPD-----EEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDP 152

Query: 120 SAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQ 179
           SAVTKGWK+NPV FDS FNQS HT++FGSPDI+P+F              Y H +EDF  
Sbjct: 153 SAVTKGWKANPVEFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTWN---SYPHEYEDFAT 209

Query: 180 SSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYD 239
            +  LD + F   + L + S  +  L   + QD  V FLHLLGCD+ GH++RPYS+ Y +
Sbjct: 210 DASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLN 269

Query: 240 NVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGL 299
           NVK +D     +   +  ++ D++T++IFTADHGMS  GSHGDGHP NT TPLVAWGAG+
Sbjct: 270 NVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGI 329

Query: 300 NKPVHNPFPVSDNY--------------TENWELSSIKRNDVKQADIASLMSYLIGVNYP 345
             P         +                 +W L  ++R DV QADIA LMS L+G+  P
Sbjct: 330 QYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCP 389

Query: 346 KNSVGELPIAYIDGKESDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHS 405
            NSVG LP+ Y+   E++++ A+  N + IL Q L K      +  F+K +   V   HS
Sbjct: 390 VNSVGNLPLGYMKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNSLFFKPFKPLVH--HS 447

Query: 406 HYLEEIETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVG 465
             L +I+ LI   S       + A+ L  +L  ++LEGLHY  TY+W  + T++T G+ G
Sbjct: 448 FSLSQIDELISAKSY------EAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTG 501

Query: 466 WIFFSFIIFLKSFILENVIDDQKASPLSHAVFGSIGI-LLNWILFYQHSPFNFYMYLLFP 524
           W+    +  L+ +   +  D  K   LS  + G + + +L+ +   +HSP  ++ Y+   
Sbjct: 502 WMIVLALHVLQCYSSLSG-DLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMT 560

Query: 525 LYFWSYIFTNRSVLRSGIKEF--FKGTSPWKRVLITISIISVYEGIVYGFFHRWTFTLIT 582
           ++ W+ IF+   ++R   K     +     K +      + + E +V+ F  R  +T   
Sbjct: 561 VFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFF 620

Query: 583 NILAFYPFIC---GVRELS-VNILWIITSVLLSTFTLFDAVKIEDLNQI---HLAGLLII 635
            I      I     +   S + +   I+   LS FTL  A   ++ N +     A    I
Sbjct: 621 LIAGVVASILLHFSIPWRSGIPVFVCISCWFLSVFTLMPAEIPDNNNLVSPFLGANDTDI 680

Query: 636 LSAFYALYKIHSRINSYTRAIFAIQIS---LVAAMLAVTHRSVISLQLRQGLPRESQVAG 692
                    +     S   +  A   S   LV+        S +++           +  
Sbjct: 681 FGWCVICDGVFVDKASNAESRIAFVTSVHKLVSCRYEAVFYSALAVV----------LMA 730

Query: 693 WIIFFVSLFVMPILHYRKPNNDYKVRLLIIYLTFAPS--FIILTI-SFESLFYFLFTSYM 749
           WI+F  +         +   +         ++T      ++ L+      +F  LF    
Sbjct: 731 WILFENASH----HSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMVLFNVAF 786

Query: 750 VQWIEIENKIKEMKTQKDENWLQVLRVSVIGFFLLQVAFFGTGNVASISSFSLESVCRLL 809
                                +                                SV R +
Sbjct: 787 FGTGNF--------ASIASFEIS-------------------------------SVYRFI 807

Query: 810 PIFDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIISMSDILSLNFFYLL 869
            IF PFLM ALL+ KL IP+ L+      +   +         L+I  SDI++++FF+L+
Sbjct: 808 TIFSPFLMAALLIFKLFIPFMLVICAFSAITKLVRVPRLGCYFLVILFSDIMTIHFFFLV 867

Query: 870 RTEGSWLDIGITISNYCLAILSSLFMLILEVLGHVLLKNVIIQ 912
           +  GSW++IG +IS++ +     +F+L+L  L ++  +++ I+
Sbjct: 868 KNTGSWMEIGNSISHFGIVSAQVVFVLLLFALTNLYTRSIRIK 910
>gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melanogaster]
          Length = 874

 Score =  799 bits (2042), Expect = 0.0
 Identities = 248/920 (26%), Positives = 437/920 (46%), Gaps = 91/920 (9%)

Query: 9   LLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQST----PTPPAKRLFLIVGDGLRADTT 64
            +A  ++ H+  L SIF IYF SP++ G++P +        PPA RL LIV DG RAD+ 
Sbjct: 2   WIAYALVVHVLLLGSIFVIYFRSPVITGLTPQKHLLYYGLEPPANRLVLIVTDGFRADSF 61

Query: 65  FDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTK 124
           F++    V        P +R + +     G+S TR+PTE+RPGH+ +IAG YED SAV +
Sbjct: 62  FEENCRYV--------PNLRKIFLREGVVGVSRTRVPTETRPGHITLIAGLYEDPSAVLR 113

Query: 125 GWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFT--QSSI 182
           GWKSNP++FD+ FN+S+ TY++G+ D+L +F    S+  +++   Y+H   DF+    + 
Sbjct: 114 GWKSNPIDFDTVFNRSSQTYAWGANDVLNVF-SHVSNGGEINLRFYNH-DLDFSPGYDAY 171

Query: 183 ELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVK 242
           E D +VF+ +  L          +   R    VFFLHLLG DTAGH ++P + ++   ++
Sbjct: 172 EEDEWVFKRVKLLL-----QQKREALQRAQNVVFFLHLLGLDTAGHVHKPGAPKFRRTLE 226

Query: 243 YIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKP 302
             +  +  +  +  + F D +TA++ TADHGM+  G                     ++ 
Sbjct: 227 KTEKGVYAIYQEFERVFPDKRTAYLLTADHGMTDSG--------------------ASRA 266

Query: 303 VHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKES 362
           V  P P    +  N E  ++  ++++QA +  LMS L+G+  P N+ G+LP+ Y++  + 
Sbjct: 267 V--PKPGGRTFMPNNEGPAMPLHELEQAQLTPLMSALLGLAPPMNNFGKLPLGYLNVSKE 324

Query: 363 DKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISEGE 422
            +  A + NA  +LEQY+  Q +    + F+ +     +  ++  ++  +  I ++ +  
Sbjct: 325 YEAMAAHVNALQLLEQYVALQKQ--HKKGFFADILLEYDVLNAEAIKRYKDTIVQLQKKR 382

Query: 423 NYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFILEN 482
            Y     I  ++ +M   LEG+ Y   Y  R +    T  F+GW+F+ + +  ++   + 
Sbjct: 383 EY--SLCIDKSQVIMSQALEGIDYYHGYYRRVLLLSTTSTFLGWMFYIYRLLSRNRASKV 440

Query: 483 VIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWS-----YIFTNRSV 537
            +  ++++ +      S  I+L   L  Q +P +   YLL P + W      +     S 
Sbjct: 441 ELVLERSNKIVRVSIVSSVIVLIICLLSQGTPLDISFYLLLPYFVWLKALQPWNINFSSS 500

Query: 538 LRSGIKEFFKGTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILAFYPFICGVREL 597
             S        TS W+ V     +I+  E +V+ FF R    L   + A Y      +  
Sbjct: 501 PASAYSVPALQTSMWQLV----LLIACAELMVFTFFERRLIALCFCVFACYNSWENFQWK 556

Query: 598 SVNIL-WIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAFY------ALYKIHSRIN 650
           S +   W+   ++LS F L           +  AG+++I +  +        Y+ H++  
Sbjct: 557 SRDFFSWLALVLILSCFPLLPLSVGYQNGYLLGAGVIVIFTNSFWNSKSRLCYRNHTK-- 614

Query: 651 SYTRAIFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRK 710
            Y+ A+  +Q  L A +    H + I+      +P   ++A W ++ V  F   +L    
Sbjct: 615 -YSNALILLQTILCAYL----HSNGIN------IPIPLKLASW-LYLVYAFASILL---S 659

Query: 711 PNNDYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEMKTQKDENW 770
             +   +RL  I       +  L  S+E++F  L T  +            ++ Q     
Sbjct: 660 KESRLDLRLAQIGFNLGSLYATLCTSYEAVFVQLLTIELNI---------SLRAQSARAE 710

Query: 771 LQVLRVSVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPF-LMGALLMLKLIIPY 829
             VLR++         + FG+GN+ASISSF        L  F PF +MG +L+  L+   
Sbjct: 711 RSVLRLAFTLLLYTFFSLFGSGNIASISSFDPNIARCYLSHFAPFVIMGLVLLKLLVPVV 770

Query: 830 GLLSTCLGILNLKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLDIGITISNYCLAI 889
            ++S            ++     L + + D++ LNF +L+R +GSWLDIG +IS++ +  
Sbjct: 771 LIMSVIYANSEFVRQHEEQIFICL-LLICDVMGLNFLFLVRNQGSWLDIGTSISHFVIME 829

Query: 890 LSSLFMLILEVLGHVLLKNV 909
           +++L ML++      LL+ +
Sbjct: 830 VTTLVMLVIFYTAKQLLRVI 849
>gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melanogaster]
          Length = 919

 Score =  787 bits (2013), Expect = 0.0
 Identities = 208/946 (21%), Positives = 356/946 (36%), Gaps = 90/946 (9%)

Query: 9   LLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTP----TPPAKRLFLIVGDGLRADTT 64
                ++ HL  L SI  IYF S ++  + P  +       PPA RL + V DGLRA + 
Sbjct: 2   WSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSV 61

Query: 65  FDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTK 124
                  V        P +R L +  A  GIS    PT +RPGH+A+  GF ED +A   
Sbjct: 62  LADHCSAV--------PDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAATLT 113

Query: 125 GWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQSSI-- 182
               NP  FDS FN+S +   +   ++  +F         + T      FE F +S I  
Sbjct: 114 ---WNPSTFDSVFNRSRNAIGWMQAEVAKVF-------THLPTGGAPLRFETFARSDISD 163

Query: 183 --ELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDN 240
              LD + F  +     N      L         +FF++L   D A H + P S  + + 
Sbjct: 164 RLRLDQWTFDKVRNFMTNEQNVQPLRDATS---VIFFVYLADIDLAEHVHMPNSLNFREK 220

Query: 241 VKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLN 300
           + Y    I    +     F D +TA++ TAD+G+S    HG G      TP + WGAG+ 
Sbjct: 221 LNYTQRGIRQTYELFESVFNDSRTAYLMTADYGISL---HGGGGERGVETPFILWGAGVK 277

Query: 301 KPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGK 360
           +   NP     N+T       +    ++Q  +A LMS LIG+  P N++  +P+ +++  
Sbjct: 278 RSAPNPGQ---NFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTS 334

Query: 361 ESDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISE 420
              +L  L+ NA  +L Q  +      D    Y    KF E   S  +E    +I+ +  
Sbjct: 335 VQYELQVLHLNAMQLLAQARILIKRHEDG-ILYLLLPKF-ESLGSAEIENYPQIIKYLVA 392

Query: 421 GENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFIL 480
            E Y  +EA+ ++ ++ ++  E + Y   Y    +    T  ++ W +   +   +    
Sbjct: 393 KEQY--EEALKVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWFYLLLVRLARESNH 450

Query: 481 ENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNRSVLRS 540
                    +  +  +    G++L  ++  Q  P     YLL P          R   + 
Sbjct: 451 PKSERKGYLTW-TTLMMCLGGLVLLELMILQRVPHLTAFYLLLPFGILILALAERP-CQD 508

Query: 541 GIKEFFKGTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILAFYPFICGVRELSVN 600
                     P   ++    I+     ++   FH     L+   +            S+ 
Sbjct: 509 R---DLMCQFPVLHLVG---IVMPGVLLILMAFHNSHIGLLYLPIVCLNNRRAFFRPSLK 562

Query: 601 I-LWIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAFYALYKIHSRINSYTRAIFAI 659
           +  W+    LLS   L   VK           + + +   + +Y     I S  R +   
Sbjct: 563 LIFWLALVFLLSGILL---VKQSASLHFITDTIGVYIGNSHVVYFSM--ILSIIRPLILG 617

Query: 660 QISLV------AAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRKPNN 713
                       A L VT   +      Q +      A W      L    +        
Sbjct: 618 HQHSTRVWIVNMAALLVTAYGIYQWDADQPVCTYVYAACW----SYLLFAFLSIPYSGTK 673

Query: 714 DYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEI------------------ 755
           D + RL +I        I+LT S  SLF  +  +  V  +E+                  
Sbjct: 674 DLRRRLELIIFNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESFSYANLKDAIANQQ 733

Query: 756 --ENKIKEMKTQKDENWLQVLRVSV----IGFFLLQVAFFGTGNVASISSFSLESVCRLL 809
                ++E + +   N L+ +R S     +    L ++FFGTG+     +F   +     
Sbjct: 734 QNNQGLEESRNESPNNPLEHVRQSYRYAALILLYLYISFFGTGHWFFNFTFKPMTSRLFF 793

Query: 810 PIFDPFLMGALLMLKLIIP-YGLLSTCLGILNLKLNFKDYTISSLIISMSDILSLNFFYL 868
           P F   ++ A ++LK+ IP   ++S+   +++            L + M+D +SL F Y 
Sbjct: 794 PQFHLHMLVAFILLKIFIPSIIVMSSIYALVSFGRKNVRSIFICLFL-MNDAMSLYFCYF 852

Query: 869 LRTEGSWLDIGITISNYCLAILSSLFMLILEVLGHVLLKNVIIQDK 914
           +   GS   +  ++    ++ +  + +L+   +    L N   +DK
Sbjct: 853 VINRGSLEKVRESLDRLLVSHVFIILLLVCSWIAKGFLANTK-KDK 897
>gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caenorhabditis elegans]
          Length = 929

 Score =  781 bits (1998), Expect = 0.0
 Identities = 272/933 (29%), Positives = 454/933 (48%), Gaps = 107/933 (11%)

Query: 9   LLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQ-STPTPPAKRLFLIVGDGLRADTTFDK 67
            L   +  HL  ++SIFD+Y+ SPLVHG+ P   ++   PAKR+F+I  DGLR DT F+K
Sbjct: 5   FLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDT-FNK 63

Query: 68  VTHPVSGKTEFLAPFIRSL-VMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGW 126
                        P++ S+       YG+S + +PTESRPGHVA+ AG  ED+SAV KGW
Sbjct: 64  YPDKS--------PYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGW 115

Query: 127 KSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFT-QSSIELD 185
           K NPV FDS FN+S++++ +GSPDI+ +F D  +     +++ Y    EDF  + +  LD
Sbjct: 116 KKNPVQFDSVFNRSSYSWMWGSPDIVNLFDDLPN----AESFSYSADEEDFASKDASNLD 171

Query: 186 AFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYID 245
            +VF H +     +  +  L+ ++R+  ++FFLHLLG DT GH  +P S +Y DN+K +D
Sbjct: 172 KWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVD 231

Query: 246 DQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHN 305
             I  +   V+ FF D KTA++FT+DHGM+ +GSHG G  +   TP VAWGAG+ +    
Sbjct: 232 SGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQ---- 287

Query: 306 PFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKE-SDK 364
                             + D+ Q D+A L+S LIG   P NS+G LP+  ++ K  S +
Sbjct: 288 ---------------GGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYE 332

Query: 365 LAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISEGENY 424
             A+  N + + EQ +  ++     + +++++ KF +K+    +E + T + ++     +
Sbjct: 333 FKAIEANFKQLKEQIIFLKNAKS-RRLWFRQFEKFGDKA----MESLRTTLAQLGRDRRF 387

Query: 425 LEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFILENVI 484
               A +L  +   +  E + +   Y+ + +   V+  FV WI       + SF+  +  
Sbjct: 388 --SVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWI-----ALVVSFLHNSTS 440

Query: 485 DDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSY-IFTNRSVLRSGIK 543
            +  +  + H +F  I  L   +LF  +   +    +   L  +   I  N S L   I+
Sbjct: 441 KENLSLLVPHHLF--IIPLACSLLFTAYCSLSMTQTIYIILPIYLISILENHSKLTQRIR 498

Query: 544 EFFKGTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILAFY--PFICGVRELSVNI 601
           E  K  S     L  +  + V+     GF   ++ T+   +L F    F+  V  L + +
Sbjct: 499 EHVKALSAQPDWLNKVLSVEVFVKPFLGFVG-FSITICIFVLTFMDRAFLAAVFVLLMAL 557

Query: 602 --------------LWIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAF----YALY 643
                          W+   ++L  F    AV +     I L  L  I++AF     +  
Sbjct: 558 PQFYSHPIVSYWSKTWLTLCLVLCIFPFLPAVGVS--THIPLCILSPIITAFLCHRLSRR 615

Query: 644 KIHSRINSYTRAIFAIQISLVAAMLAVTHRSVISLQLRQ--------------GLPRESQ 689
              +RI      +  +Q S  A M+AV +     ++                    +   
Sbjct: 616 SCLTRIQRMLELMIYVQ-SATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSLQPPS 674

Query: 690 VAGWIIFFVSLFVMPILHYRKPNNDYKVRLLIIY-LTFAPSFIILTISFESLFYFLFTSY 748
           +A WI +  +   + ++        Y V  LI Y L F   + +L+IS+ESLF  +F   
Sbjct: 675 IARWISW--TSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFLVL 732

Query: 749 MVQWIEIE----NKIKEMKTQKDENWLQV-----LRVSVIGFFLLQVAFFGTGNVASISS 799
           +  ++  E    + ++ ++ + D   +       LR +V+    +    FGTGN ASI+S
Sbjct: 733 LTLFVRFEFGHLSDVELLQLKVDSTKISTGEYVELRRTVVCVSFVLCPLFGTGNFASINS 792

Query: 800 FSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLI---IS 856
           F+  ++   + +F PF M  LL+LKL+IP  L+++    +   + F   +I  L    + 
Sbjct: 793 FNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASI---VRFDQESIQRLCCFSLI 849

Query: 857 MSDILSLNFFYLLRTEGSWLDIGITISNYCLAI 889
            +D +S+ FF+ LR EGSWLDIG++IS + +++
Sbjct: 850 FTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSM 882
>gb|AAF54657.1| (AE003692) CG6790 gene product [Drosophila melanogaster]
 gb|AAL28155.1| (AY060607) GH02677p [Drosophila melanogaster]
          Length = 858

 Score =  644 bits (1646), Expect = 0.0
 Identities = 131/745 (17%), Positives = 272/745 (35%), Gaps = 77/745 (10%)

Query: 189 FRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQI 248
           F HL  L    T  + L+     +  V  ++L     A     P    +   +      I
Sbjct: 136 FSHLSDLRRRLTKRACLEKLWYANKLVMLVNLAEVGGAS----PLDIGFQMKLHNTQRNI 191

Query: 249 PILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFP 308
               + +   F D KTA+++T+ HG++ FGSHG G       P + WGAG+     N   
Sbjct: 192 RDAYELIEATFNDSKTAYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGVKHVTEN--- 248

Query: 309 VSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESDKLAAL 368
           ++ ++  N     ++ + + Q  +A LMS LIG+  P N++  LP  Y+         ++
Sbjct: 249 ITSDFVLN-NGVGMQLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSREYARKSV 307

Query: 369 YNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISEGENYLEQ- 427
           + NA  +L Q   K    +  +  +          H    ++ +  +Q+I+  +N ++  
Sbjct: 308 HLNALQLLTQA--KAIIRLHERGVF----------HKWLPKDKDLDLQQIAYYQNQMDHL 355

Query: 428 -------EAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFIL 480
                  +A+  +   +++ L+ L +   Y    +        +GW F+  +   ++ + 
Sbjct: 356 LDMGWRSKALETSTLAIKVALKSLKFYHNYYHIPLVVTTVLALLGWQFYQLVKLSQNVMA 415

Query: 481 ENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNRSVLRS 540
            + +     +  +     S+G+LL  ++F Q +PF   + L+ P   W            
Sbjct: 416 PHYMRRGYLTWCT-IFLASLGLLLGEMVFLQWAPFMTVICLVVPFGVWCMTLAALPQNGG 474

Query: 541 GIKEFFKGT----SPWKRVLITI---SIISVYEGIVYGFFHRWTFTLITNILAFYPFICG 593
            I E  K       P   ++ +I     +S+   +  GF++R                  
Sbjct: 475 WIFEPLKHLRWIVGPAAVMIASIYCNCPLSLAYILCVGFYNRRG-------------WLH 521

Query: 594 VRELSVNILWIITSVLLSTFTL--FDAVKIEDLNQIHLAG-LLIILSAFYALYKIHSRIN 650
                +  L ++  +    ++      +   +   +  A  +L+++     L + H    
Sbjct: 522 PSPKFLAWLALVLLLGGFLWSQKGMQILMTTNYRVVLQAISMLVVIVRPCVLNENHKWKV 581

Query: 651 SYTRAIFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQV--AGWIIFFVSLFVMPILHY 708
                      ++                   G P    +  A W  + +  F       
Sbjct: 582 WVINGGILFVAAIGIF------------LKEMGKPVPLYLFAANWA-YLIYAFAS---VP 625

Query: 709 RKPNNDYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKE----MKT 764
                  + RL +I        ++L+ S+ SLF           +E+  K KE    +K 
Sbjct: 626 CSSRTTPQSRLELIRFNLLTLHVLLSDSYVSLFAQGLIIEYQMGLEVHEKFKEADEDVKI 685

Query: 765 QKDENWLQV-LRVSVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGALLML 823
                 LQ+  R +V        + FGTG+     ++   S    LP     L+  L+++
Sbjct: 686 LTSSKHLQMCYRFAVSILLYFYASLFGTGHWVGGFTYLANSARLFLPDSSSGLVPLLVLI 745

Query: 824 KLIIP-YGLLSTCLGILNLKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLDIGITI 882
            L+IP   ++++ + + +          SSL++ + + + L F   +     W     ++
Sbjct: 746 HLLIPSIVIMASVVALSSFGRQQIRTIFSSLML-ICNAVVLFFVVFVPHNAYWPMAHPSV 804

Query: 883 SNYCLAILSSLFMLILEVLGHVLLK 907
            +  LA L+ + +L  E +  +  +
Sbjct: 805 VHALLAQLTVILILACESIVTIFFR 829
 Score = 94.9 bits (234), Expect = 5e-18
 Identities = 41/136 (30%), Positives = 61/136 (44%), Gaps = 18/136 (13%)

Query: 8   TLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTP----TPPAKRLFLIVGDGLRADT 63
              +  VL HL  L  I  I++ S  +  + P ++       P A RL + + +GLRADT
Sbjct: 3   LWKSKVVLVHLLLLICIMRIFYQSGPLSQLEPQKTLLDMGVPPAADRLVVFLLEGLRADT 62

Query: 64  TFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVT 123
            F              A +IR +++     GIS T +PT +R   VA+ AGF    S + 
Sbjct: 63  LFSDNCS--------GAVYIRDIILRQGLVGISKTSVPTLTRSAEVALFAGFNPMPSIL- 113

Query: 124 KGWKSNPVNFDSFFNQ 139
                   NFD+ FN+
Sbjct: 114 -----PTSNFDTIFNR 124
>ref|XP_082200.1| (XM_082200) CG6790 [Drosophila melanogaster]
          Length = 656

 Score =  568 bits (1449), Expect = e-160
 Identities = 113/677 (16%), Positives = 240/677 (34%), Gaps = 81/677 (11%)

Query: 257 KFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTEN 316
             F    T  +          GSHG G       P + WGAG+     N   ++ ++  N
Sbjct: 6   HTFIHQHTVLLI--------SGSHGGGSDEEREAPFLLWGAGVKHVTEN---ITSDFVLN 54

Query: 317 WELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESDKLAALYNNARSIL 376
                ++ + + Q  +A LMS LIG+  P N++  LP  Y+         +++ NA  +L
Sbjct: 55  -NGVGMQLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSREYARKSVHLNALQLL 113

Query: 377 EQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISEGENYLEQ--------E 428
            Q   K    +  +  +          H    ++ +  +Q+I+  +N ++         +
Sbjct: 114 TQA--KAIIRLHERGVF----------HKWLPKDKDLDLQQIAYYQNQMDHLLDMGWRSK 161

Query: 429 AITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFILENVIDDQK 488
           A+  +   +++ L+ L +   Y    +        +GW F+  +   ++ +  + +    
Sbjct: 162 ALETSTLAIKVALKSLKFYHNYYHIPLVVTTVLALLGWQFYQLVKLSQNVMAPHYMRRGY 221

Query: 489 ASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNRSVLRSGIKEFFKG 548
            +  +     S+G+LL  ++F Q +PF   + L+ P   W             I E  K 
Sbjct: 222 LTWCT-IFLASLGLLLGEMVFLQWAPFMTVICLVVPFGVWCMTLAALPQNGGWIFEPLKH 280

Query: 549 T----SPWKRVLITI---SIISVYEGIVYGFFHRWTFTLITNILAFYPFICGVRELSVNI 601
                 P   ++ +I     +S+   +  GF++R                       +  
Sbjct: 281 LRWIVGPAAVMIASIYCNCPLSLAYILCVGFYNRRG-------------WLHPSPKFLAW 327

Query: 602 LWIITSVLLSTFTL--FDAVKIEDLNQIHLAG-LLIILSAFYALYKIHSRINSYTRAIFA 658
           L ++  +    ++      +   +   +  A  +L+++     L + H            
Sbjct: 328 LALVLLLGGFLWSQKGMQILMTTNYRVVLQAISMLVVIVRPCVLNENHKWKVWVINGGIL 387

Query: 659 IQISLVAAMLAVTHRSVISLQLRQGLPRESQV--AGWIIFFVSLFVMPILHYRKPNNDYK 716
              ++                   G P    +  A W  + +  F              +
Sbjct: 388 FVAAIGIF------------LKEMGKPVPLYLFAANWA-YLIYAFAS---VPCSSRTTPQ 431

Query: 717 VRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKE----MKTQKDENWLQ 772
            RL +I        ++L+ S+ SLF           +E+  K KE    +K       LQ
Sbjct: 432 SRLELIRFNLLTLHVLLSDSYVSLFAQGLIIEYQMGLEVHEKFKEADEDVKILTSSKHLQ 491

Query: 773 V-LRVSVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGALLMLKLIIP-YG 830
           +  R +V        + FGTG+     ++   S    LP     L+  L+++ L+IP   
Sbjct: 492 MCYRFAVSILLYFYASLFGTGHWVGGFTYLANSARLFLPDSSSGLVPLLVLIHLLIPSIV 551

Query: 831 LLSTCLGILNLKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLDIGITISNYCLAIL 890
           ++++ + + +          SSL++ + + + L F   +     W     ++ +  LA L
Sbjct: 552 IMASVVALSSFGRQQIRTIFSSLML-ICNAVVLFFVVFVPHNAYWPMAHPSVVHALLAQL 610

Query: 891 SSLFMLILEVLGHVLLK 907
           + + +L  E +  +  +
Sbjct: 611 TVILILACESIVTIFFR 627
>pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast
           (Schizosaccharomyces pombe)
 dbj|BAA21454.1| (AB004539) ORF YLL031c [Schizosaccharomyces pombe]
 emb|CAA16901.1| (AL021766) hypothetical protein [Schizosaccharomyces pombe]
          Length = 918

 Score =  542 bits (1382), Expect = e-152
 Identities = 120/864 (13%), Positives = 250/864 (28%), Gaps = 145/864 (16%)

Query: 4   KTRTTLL-AVGVLFHLFYLWSIF--------DIYFISPLVHGMS--------------PY 40
            T  T       +F    L S F               +++  S                
Sbjct: 14  STIGTWKYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSS 73

Query: 41  QSTPTPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISH-TR 99
                   +R  +++ D LR D               F  P+  S++    +Y       
Sbjct: 74  GCWAPKIFERAVIVIIDALRYDFLIPYN-DSNYYHNAFTTPYETSVLHPENSYLTQFIAD 132

Query: 100 MPTESRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQ----STHTYSFGSPDILPMF 155
            PT +      +  G       +   +    ++ D+   Q           G      +F
Sbjct: 133 APTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSLDKQIVLLGDDTWDVLF 192

Query: 156 KDGASDPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNV 215
            D  ++      + ++           +++ +VF ++                   + +V
Sbjct: 193 HDYLNETLSQPAFSFNVPDLHGV--DNKVNQYVFDYIKD----------------ANFDV 234

Query: 216 FFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMS 275
              H LG D  GH   P      D +  +D  +  ++D +     DD T  I   DHGM 
Sbjct: 235 LIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL-----DDSTLLIVMGDHGMD 289

Query: 276 AFGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASL 335
             G+HG    +   + L  +              +  Y +       K     Q D+   
Sbjct: 290 NKGNHGGDSFDEINSVLWMYS----------KKPTFGYLKQPG----KVLSANQVDLVPT 335

Query: 336 MSYLIGVNYPKNSVG-ELPIAYIDGKESDKLAALYNNARSILEQYLVKQDEVIDSQFFYK 394
           +S L+G   P  ++G  +P  +    +     A   N   +                F+ 
Sbjct: 336 LSLLLGNPIPYGNLGTLIPEPFYYYGDEYLSKAQKINIGQLNR--------------FFS 381

Query: 395 EYFK-FVEKSHSHYLEEIETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTYNWR 453
           EY     +   S   +   + + +      +L+        +  +   +   Y       
Sbjct: 382 EYDLDASDFLSSSVHKNNNSYLDQ-----YFLD-------FDYAR---DAFSYFKAIWAE 426

Query: 454 FIRTIVTFGFVGWIF--FSFIIFLKSFILENVIDDQKASPLSHAVFGSIGILLNWILFYQ 511
           F    +  GF+  I   F+  + ++   +   +    A  +   +   + ++L       
Sbjct: 427 FSLFPMIIGFLLLIIGGFNLALLMQDKSVIFRMSANMAPSVMKCLPVCLILILANNEL-- 484

Query: 512 HSPFNFYMYLLFPLYFWSYIFTNRSVLRSGIKEFFKGTSPWKRVLITISIISVYEGIVYG 571
           HSPF    Y+L P ++     +    L    K F K       + IT   +  +    + 
Sbjct: 485 HSPFPAEFYVLLPSFYILLN-SFNQKLMEYFKGFVKLDYFS--IFITFLHVCSFGSNSFT 541

Query: 572 FFHRWTFTLITNILAFYPFICGVRELSVNILWIITSVLLSTFTLFDAV------------ 619
            +       +   +    F     E+S  +    T   L+   L                
Sbjct: 542 VWEDRLCHFLIITIGLVMFCKCFSEMS-PLFACSTYSALAFILLQVISSYVTNCREEQGA 600

Query: 620 -------KIEDLNQ---------IHLAGLLIILSAFYALYKIHSRINSYTRAIFA-IQIS 662
                     D +             + +L ++   +    +   +  Y  +I    ++ 
Sbjct: 601 FCVSTYISTPDNSLRTLIVLALMALSSIILPLILQLHLRRVLGLSLKLYHLSILYFFELI 660

Query: 663 LVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRKPNNDYKVRLLII 722
                +A    +  +L  +Q       +A    + + +  + I  +   +     ++ +I
Sbjct: 661 SSIFWIAHHVFANDALLEKQYHHVLYSLAN--TYVICILGVLIWQFFLLSRSKFAKINVI 718

Query: 723 ---YLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEMKTQKDENWLQVLRVSVI 779
              Y  FA  +  L+      F      ++  +      +  ++ ++ +  +     SV 
Sbjct: 719 ERSYFVFALLYSFLS------FLQRPLGHLSLFSCFLQILLLIQLKQWQPSVGHNFFSVT 772

Query: 780 GFFLLQVAFFGTGNVASISSFSLE 803
              L    FF TGN A+ISS    
Sbjct: 773 LGLLGLSHFFTTGNQAAISSLDWN 796
>dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [Mus musculus]
          Length = 391

 Score =  516 bits (1317), Expect = e-145
 Identities = 195/396 (49%), Positives = 259/396 (65%), Gaps = 11/396 (2%)

Query: 7   TTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTFD 66
               A+G+L H  +  SIFDIYF SPLVHGM+P  +   PPAKRL L V DGLRADT ++
Sbjct: 2   LLFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYE 61

Query: 67  KVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGW 126
                +       APFIR+++M+  ++G+SHTR+PTESRPGHVA+IAGFYEDVSAV KGW
Sbjct: 62  -----LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 127 KSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDF-TQSSIELD 185
           K NPV FDS FN+S +T+S+GSPDILPMF  GAS  + V T+ YD   EDF    + +LD
Sbjct: 117 KENPVEFDSLFNESKYTWSWGSPDILPMFAKGAS-GDHVYTYSYDAQREDFGAHDATKLD 175

Query: 186 AFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYID 245
            +VF  +   F  +  N +L  ++ ++  VFFLHLLG DT GH++RP S EY DN+K +D
Sbjct: 176 TWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVD 235

Query: 246 DQIPILIDKVNKFFADD-KTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPV- 303
           D +  ++     F+ DD KTAFIFT+DHGM+ +GSHG GHP+ T TP V WGAG+  P  
Sbjct: 236 DGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQN 295

Query: 304 HNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESD 363
            +     D + + W L + KR DV QADIA LM+ LIGV +P NSVG LP+ Y++     
Sbjct: 296 VSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLF 355

Query: 364 KLAALYNNARSILEQYLVKQDEVIDS--QFFYKEYF 397
           K  +++ NA  ILEQ+ VK  +  ++   F +  + 
Sbjct: 356 KAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFK 391
>gb|AAF54658.1| (AE003692) CG5342 gene product [Drosophila melanogaster]
          Length = 559

 Score =  445 bits (1135), Expect = e-123
 Identities = 94/608 (15%), Positives = 196/608 (31%), Gaps = 81/608 (13%)

Query: 314 TENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESDKLAALYNNAR 373
             N     +  + +    + +LMS L+GV  P  S G LP   ++     +  A+  NA+
Sbjct: 1   MANEAGLRLPLHVLNTPHLTALMSALLGVPPPVYSRGMLPKGMLNASLRYEANAMLINAK 60

Query: 374 SILEQYLVKQ--DEVIDSQFF--YKEYFKFVEKSHSHYLEEIETLIQRISEGENYLEQEA 429
            +L Q    +         F+  ++    FV++S +            + +   +     
Sbjct: 61  QLLAQARRLRELHPKRMPAFWLSFQMMDNFVKESLA------------LKKQRRFR--AL 106

Query: 430 ITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFL----KSFILENVID 485
           +  +   M + ++G+ Y   Y      T V+F  + WI +     L    K   L   I 
Sbjct: 107 LDYSCNYMPVLIKGMDYFKDYYRHVSITAVSFAGIAWI-YCLRCHLTVGKKCRNLIE-IQ 164

Query: 486 DQKASPLSHAVFG----SIGILLNWILFYQHSPFNFYMYLLFPLYFW---SYIFTNRSVL 538
           +  +S       G      G+L+  ++  +  P      LL P  +W     I   R  +
Sbjct: 165 EVISSKRLVYARGFHRLLTGVLVIIMML-ERIPLVVQAILLIPSLYWRTTLKILGERPKM 223

Query: 539 RSGIKEFFKGTSPWKRVLITISIISVYEGIVY-GFFHRWTFTLITNILAFYPFICGVREL 597
                              ++   ++   I + GFF R+   +     A Y         
Sbjct: 224 VCR---------------KSLMSTALLALICFGGFFRRYILAVGYLGFASYNNREAF--K 266

Query: 598 SVNILWIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAFYALYKIHSRINSYTRAIF 657
                + +  +LL   T+  A+          A +  I                      
Sbjct: 267 RRGHQFYLWLLLLLGLTVVSALPESLGCSQPGALMFSIFLTVLRPLACG----------V 316

Query: 658 AIQISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRKP-NNDYK 716
            + +    + + V   ++  +           + GW  + + L     L +         
Sbjct: 317 YLNLLTWLSNIPVLLAALEYI-----------LIGWHPWIMYLVSWIYLGFLVLWQRRNL 365

Query: 717 VRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEMKTQKDENWLQVLRV 776
               + +   +  + +   S+ES+   +    +   + ++ K  E    K          
Sbjct: 366 QASEVFFFDLSTLYTLTCTSYESVVIQMLAMELQLALRMKLKRNESIGPKTAAH------ 419

Query: 777 SVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCL 836
                     + F  G+  +   F L+ +      + P   G +++LKLI+P+ L+   +
Sbjct: 420 --YILVYSWYSLFIIGSFPAFDDF-LDILHETCFGYSPLTYGLVMVLKLILPWLLVLCIM 476

Query: 837 GILNLKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLDIGITISNYCLAILSSLFML 896
                 L   +  I   ++ M+  +SL   + +   G W DI    + + +  +  L  L
Sbjct: 477 AGNYKSLASYEQQIFVRLLLMNSAMSLVLLHGITNVGPWRDILSRFAEFAVVHVFPLVWL 536

Query: 897 ILEVLGHV 904
           +L  L  +
Sbjct: 537 LLWRLTQL 544
>dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:1351629,
           evidence:ISS~phosphatidylinositol glycan, class
           N~putative [Mus musculus]
          Length = 320

 Score =  403 bits (1027), Expect = e-111
 Identities = 158/315 (50%), Positives = 207/315 (65%), Gaps = 9/315 (2%)

Query: 7   TTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTFD 66
               A+G+L H  +  SIFDIYF SPLVHGM+P  +   PPAKRL L V DGLRADT ++
Sbjct: 2   LLFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYE 61

Query: 67  KVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGW 126
                +       APFIR+++M+  ++G+SHTR+PTESRPGHVA+IAGFYEDVSAV KGW
Sbjct: 62  -----LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 127 KSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDF-TQSSIELD 185
           K NPV  DS FN+  +T+S+GSPDILPMF  GAS  + V T+ YD   EDF    + +LD
Sbjct: 117 KENPVESDSLFNERKYTWSWGSPDILPMFAKGAS-GDHVYTYSYDAQREDFGAHDATKLD 175

Query: 186 AFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYID 245
            +VF  +   F  +  N +L  ++ ++  VFFLHLLG DT GH++RP S EY DN+K +D
Sbjct: 176 TWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVD 235

Query: 246 DQIPILIDKVNKFFADD-KTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPV- 303
           D +  ++     F+ DD KTAFIFT+DHGM+ +GSHG GHP+ T TP V WGAG+  P  
Sbjct: 236 DGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQN 295

Query: 304 HNPFPVSDNYTENWE 318
            +     D + +   
Sbjct: 296 VSAQQYDDEFLKGTN 310
>ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans]
          Length = 348

 Score =  388 bits (989), Expect = e-106
 Identities = 146/373 (39%), Positives = 216/373 (57%), Gaps = 36/373 (9%)

Query: 9   LLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQ-STPTPPAKRLFLIVGDGLRADTTFDK 67
            L   +  HL  ++SIFD+Y+ SPLVHG+ P   ++   PAKR+F+I  DGLR DT F+K
Sbjct: 5   FLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDT-FNK 63

Query: 68  VTHPVSGKTEFLAPFIRSL-VMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGW 126
                        P++ S+       YG+S + +PTESRPGHVA+ AG  ED+SAV KGW
Sbjct: 64  YPDKS--------PYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGW 115

Query: 127 KSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFT-QSSIELD 185
           K NPV FDS FN+S++++ +GSPDI+ +F D  +     +++ Y    EDF  + +  LD
Sbjct: 116 KKNPVQFDSVFNRSSYSWMWGSPDIVNLFDDLPN----AESFSYSADEEDFASKDASNLD 171

Query: 186 AFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYID 245
            +VF H +     +  +  L+ ++R+  ++FFLHLLG DT GH  +P S +Y DN+K +D
Sbjct: 172 KWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVD 231

Query: 246 DQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHN 305
             I  +   V+ FF D KTA++FT+DHGM+ +GSHG G  +   TP VAWGAG+ +    
Sbjct: 232 SGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQ---- 287

Query: 306 PFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKE-SDK 364
                             + D+ Q D+A L+S LIG   P NS+G LP+  ++ K  S +
Sbjct: 288 ---------------GGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYE 332

Query: 365 LAALYNNARSILE 377
             A+  N + ++ 
Sbjct: 333 FKAIEANFKQVIN 345
>ref|NP_491098.1| (NM_058697) M01B12.2.p [Caenorhabditis elegans]
 pir||T33168 hypothetical protein M01B12.2 - Caenorhabditis elegans
          Length = 559

 Score =  387 bits (984), Expect = e-106
 Identities = 121/530 (22%), Positives = 223/530 (41%), Gaps = 66/530 (12%)

Query: 408 LEEIETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWI 467
           +E + T + ++     +    A +L  +   +  E + +   Y+ + +   V+  FV WI
Sbjct: 1   MESLRTTLAQLGRDRRF--SVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWI 58

Query: 468 FFSFIIFLKSFILENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYF 527
                  + SF+  +   +  +  + H +F  I  L   +LF  +   +    +   L  
Sbjct: 59  -----ALVVSFLHNSTSKENLSLLVPHHLF--IIPLACSLLFTAYCSLSMTQTIYIILPI 111

Query: 528 WSY-IFTNRSVLRSGIKEFFKGTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILA 586
           +   I  N S L   I+E  K  S     L  +  + V+     GF   ++ T+   +L 
Sbjct: 112 YLISILENHSKLTQRIREHVKALSAQPDWLNKVLSVEVFVKPFLGFVG-FSITICIFVLT 170

Query: 587 FY--PFICGVRELSVNI--------------LWIITSVLLSTFTLFDAVKIEDLNQIHLA 630
           F    F+  V  L + +               W+   ++L  F    AV +     I L 
Sbjct: 171 FMDRAFLAAVFVLLMALPQFYSHPIVSYWSKTWLTLCLVLCIFPFLPAVGVS--THIPLC 228

Query: 631 GLLIILSAF----YALYKIHSRINSYTRAIFAIQISLVAAMLAVTHRSVISLQLRQ---- 682
            L  I++AF     +     +RI      +  +Q S  A M+AV +     ++       
Sbjct: 229 ILSPIITAFLCHRLSRRSCLTRIQRMLELMIYVQ-SATAFMIAVVNYGFEKVKKLIQNNW 287

Query: 683 ----------GLPRESQVAGWIIFFVSLFVMPILHYRKPNNDYKVRLLIIY-LTFAPSFI 731
                        +   +A WI +  +   + ++        Y V  LI Y L F   + 
Sbjct: 288 KKKKSNSKSSQSLQPPSIARWISW--TSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYS 345

Query: 732 ILTISFESLFYFLFTSYMVQWIEIE----NKIKEMKTQKDENWLQV-----LRVSVIGFF 782
           +L+IS+ESLF  +F   +  ++  E    + ++ ++ + D   +       LR +V+   
Sbjct: 346 LLSISYESLFMLIFLVLLTLFVRFEFGHLSDVELLQLKVDSTKISTGEYVELRRTVVCVS 405

Query: 783 LLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILNLK 842
            +    FGTGN ASI+SF+  ++   + +F PF M  LL+LKL+IP  L+++    +   
Sbjct: 406 FVLCPLFGTGNFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASI--- 462

Query: 843 LNFKDYTISSLI---ISMSDILSLNFFYLLRTEGSWLDIGITISNYCLAI 889
           + F   +I  L    +  +D +S+ FF+ LR EGSWLDIG++IS + +++
Sbjct: 463 VRFDQESIQRLCCFSLIFTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSM 512
>pir||T02245 hypothetical protein P1.11659_3 - human
 gb|AAC07985.1| (AC004472) P1.11659_3 [Homo sapiens]
          Length = 880

 Score =  378 bits (962), Expect = e-103
 Identities = 69/465 (14%), Positives = 128/465 (26%), Gaps = 89/465 (19%)

Query: 1   MWNKTRTTLLAVGVLFHLFYLW-SIFDIYFISPLVHGMS------------------PYQ 41
           M   +    LA         +             +   S                  P  
Sbjct: 1   MQKASVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGA 60

Query: 42  STPTPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMP 101
                   R+ L++ D LR D    + +H +        P    L         S    P
Sbjct: 61  CWMASRFSRVVLVLIDALRFDFAQPQHSHRILEIQ----PHHARLYR-------SQVDPP 109

Query: 102 TESRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQ----STHTYSFGSPDILPMFKD 157
           T +     A+  G           + S+ +  D+   Q           G      +F  
Sbjct: 110 TTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDDTWKDLFPG 169

Query: 158 GASDPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFF 217
             S      ++          +    +D  +  HL                   + +V  
Sbjct: 170 AFSKAFFFPSFN--------VRDLDTVDNGILEHLY------------PTMDSGEWDVLI 209

Query: 218 LHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAF 277
            H LG D  GH + P+  E    +  +D  I  L++++        T  +   DHGM+  
Sbjct: 210 AHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLEN-----DTLLVVAGDHGMTTN 264

Query: 278 GSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMS 337
           G HG          L  +      P   P                +   + Q  +   ++
Sbjct: 265 GDHGGDSELEVSAALFLYSPTAVFPSTPPE---------------EPEVIPQVSLVPTLA 309

Query: 338 YLIGVNYPKNSVGELPIAYIDG--------KESDKLAALYNNARSILEQYLV--KQDEVI 387
            L+G+  P  ++GE+      G            + +AL+ NA+ +           + +
Sbjct: 310 LLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDL 369

Query: 388 DSQFFYKEYFKFVEKSHSHYLEEIETLIQRISEGENYLEQEAITL 432
            ++  ++    F + S      + + L+Q     E  L      L
Sbjct: 370 QAKELHQLQNLFSKASA-----DYQWLLQSPKGAEATLPTVIAEL 409
>ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class O [Mus musculus]
 dbj|BAA96254.1| (AB038560) Pig-o [Mus musculus]
          Length = 1101

 Score =  347 bits (883), Expect = 4e-94
 Identities = 70/483 (14%), Positives = 127/483 (25%), Gaps = 93/483 (19%)

Query: 1   MWNKTRTTLLAVGVLFHLFYLW-SIFDIYFISPLVHGMS------------------PYQ 41
           M   +    LA         +             +   S                  P  
Sbjct: 9   MRKVSVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNQSSCQELPGPGPLPWGSHGKPGA 68

Query: 42  STPTPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVM---------NNAT 92
                   R+ L++ D LR D         V G+     PF+  L           ++  
Sbjct: 69  CWMPSRFSRVVLVLIDALRFDFAQP-QRSHVPGEPPVSVPFLGKLGSLQRILESQPHHGR 127

Query: 93  YGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQ----STHTYSFGS 148
              S    PT +     A+  G           + S+ +  D+   Q           G 
Sbjct: 128 LYRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNVIQQLNSAGRRVVFMGD 187

Query: 149 PDILPMFKDGASDPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYE 208
                +F    S                  +    +D  +  HL                
Sbjct: 188 DTWRDLFPGAFS--------QAFFFSSFNVRDLHTVDNGILEHLY------------PTL 227

Query: 209 IRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIF 268
                +V   H LG D  GH + P+  E    +  +D  I  LI+++        T  + 
Sbjct: 228 DGGSWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLIERLEN-----DTLLVV 282

Query: 269 TADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVK 328
             DHGM+  G HG          L  +      P   P                +   + 
Sbjct: 283 AGDHGMTMNGDHGGDSELEVSAALFLYSPTALFPSVPPE---------------EPEVIP 327

Query: 329 QADIASLMSYLIGVNYPKNSVGELPIAYIDG---------KESDKLAALYNNARSILEQY 379
           Q  +   ++ L+G+  P  + GE+      G             +++AL+ NA+ +    
Sbjct: 328 QVSLVPTLALLLGLPIPFGNTGEVMAELFSGGSDSSHPHSSALAQVSALHINAQQVSRFL 387

Query: 380 LV--KQDEVIDSQFFYKEYFKFVEKSHS--HYLEEIETLIQRI-------SEGENYLEQE 428
                  + +  +  ++    F + S    H+L + +     +        +        
Sbjct: 388 HTYSAATQDLQVKELHRLQTLFSKASARYQHFLRDPQEAEAALSTLTAEFQQFLRGARAL 447

Query: 429 AIT 431
            I 
Sbjct: 448 CIE 450
>gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarrowia lipolytica]
          Length = 860

 Score =  323 bits (822), Expect = 7e-87
 Identities = 86/435 (19%), Positives = 150/435 (33%), Gaps = 69/435 (15%)

Query: 1   MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLR 60
           +W +    +  V +      L           L+ G +  + +   P ++  ++V D  R
Sbjct: 2   LWKRWTLAVTIVVLQLAAVLL-FARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFR 60

Query: 61  ADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVS 120
           +D  F   ++             + +    A    +H+  PT + P    +  G   +  
Sbjct: 61  SDFAFSDQSN--------CPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFL 112

Query: 121 AVTKGWKSNPV-----NFDSFFNQ----STHTYSFGSPDILPMFKDGASDPNKVDTWMYD 171
                   +       N DS+  Q        + FG    + +F     D     ++   
Sbjct: 113 DAVLNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASF--- 169

Query: 172 HTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYR 231
                F     E+D  V RH+D      T           + +V  LH LG D  GH   
Sbjct: 170 -----FVSDYTEVDNNVTRHIDTQLDQKT-----------EWDVLILHYLGLDHIGHKTG 213

Query: 232 PYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTP 291
           P S       K +DD    L +       DD T  I   DHGM+  G+HG      T   
Sbjct: 214 PESPFMPAKQKEMDDIFDKLYNS-----CDDDTVLILLGDHGMNEVGNHGGSSAGETSAA 268

Query: 292 LVAWGAGLNKPV------HNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYP 345
           +V                 +P P +D Y  +        + + Q D+   ++ L+G+N P
Sbjct: 269 MVFASPKFETAQLTETAETSPLPWTDTYKYH--------SRMDQTDLVPTLTALLGLNTP 320

Query: 346 KNSVGELPIAYIDG-KESDKLAALYNNARSILEQYLVKQDEVIDSQFFY----------- 393
           KN++G L    +      D+L  L NNA  +++    +     D++  Y           
Sbjct: 321 KNNLGVLVSQMLGLWSPEDQLNVLKNNADQMVQILQGQASRESDAKEVYELYDTLNSNPS 380

Query: 394 -KEYFKFVEKSHSHY 407
            K+Y+ F+ ++ S+ 
Sbjct: 381 VKDYYNFLYEAQSYL 395
 Score =  323 bits (822), Expect = 7e-87
 Identities = 86/435 (19%), Positives = 150/435 (33%), Gaps = 69/435 (15%)

Query: 1   MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLR 60
           +W +    +  V +      L           L+ G +  + +   P ++  ++V D  R
Sbjct: 2   LWKRWTLAVTIVVLQLAAVLL-FARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFR 60

Query: 61  ADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVS 120
           +D  F   ++             + +    A    +H+  PT + P    +  G   +  
Sbjct: 61  SDFAFSDQSN--------CPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFL 112

Query: 121 AVTKGWKSNPV-----NFDSFFNQ----STHTYSFGSPDILPMFKDGASDPNKVDTWMYD 171
                   +       N DS+  Q        + FG    + +F     D     ++   
Sbjct: 113 DAVLNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASF--- 169

Query: 172 HTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYR 231
                F     E+D  V RH+D      T           + +V  LH LG D  GH   
Sbjct: 170 -----FVSDYTEVDNNVTRHIDTQLDQKT-----------EWDVLILHYLGLDHIGHKTG 213

Query: 232 PYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTP 291
           P S       K +DD    L +       DD T  I   DHGM+  G+HG      T   
Sbjct: 214 PESPFMPAKQKEMDDIFDKLYNS-----CDDDTVLILLGDHGMNEVGNHGGSSAGETSAA 268

Query: 292 LVAWGAGLNKPV------HNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYP 345
           +V                 +P P +D Y  +        + + Q D+   ++ L+G+N P
Sbjct: 269 MVFASPKFETAQLTETAETSPLPWTDTYKYH--------SRMDQTDLVPTLTALLGLNTP 320

Query: 346 KNSVGELPIAYIDG-KESDKLAALYNNARSILEQYLVKQDEVIDSQFFY----------- 393
           KN++G L    +      D+L  L NNA  +++    +     D++  Y           
Sbjct: 321 KNNLGVLVSQMLGLWSPEDQLNVLKNNADQMVQILQGQASRESDAKEVYELYDTLNSNPS 380

Query: 394 -KEYFKFVEKSHSHY 407
            K+Y+ F+ ++ S+ 
Sbjct: 381 VKDYYNFLYEAQSYL 395
>ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thaliana]
 gb|AAF18652.1| (AC006592) unknown protein [Arabidopsis thaliana]
          Length = 897

 Score =  313 bits (795), Expect = 9e-84
 Identities = 95/405 (23%), Positives = 155/405 (37%), Gaps = 61/405 (15%)

Query: 5   TRTTLLAV-GVLFHLFYL-WSIFDIYFISPLVHGMSPYQSTPTP---------------P 47
           TR T+  V G+L  +  L   +F  + + P + G+S  +S   P               P
Sbjct: 9   TRLTIFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHP 68

Query: 48  AK-RLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGI-SHTRMPTESR 105
            K RL   V DGL A+    K   P     +   P+ +SL+ N    G  +    PT + 
Sbjct: 69  EKLRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTM 128

Query: 106 PGHVAMIAGFYEDVSAVTKGWKSNPVNFDS----FFNQSTHTYSFGSPDILPMFKDGASD 161
           P   AM++G       V   + +  +  D+    FF         G    L +F      
Sbjct: 129 PRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMR 188

Query: 162 PNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLL 221
            + V ++        F + ++++D  V RHL                   D N+  LH L
Sbjct: 189 HDGVSSF--------FVKDTVQVDRNVSRHLPDE------------LNSDDWNLLILHYL 228

Query: 222 GCDTAGHSYRPYSAEYYDNVKYIDDQIPILI--DKVNKFFADDKTAFIFTADHGMSAFGS 279
           G D  GH+    S      +K +DD +  +     +++     +T  I  +DHGM+  G+
Sbjct: 229 GLDHVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGN 288

Query: 280 HGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYL 339
           HG      T + ++  G   N                 + +S   N   Q D+A  ++ L
Sbjct: 289 HGGSSYEETDSLMLFIGLNSNIS---------------DYASATNNVAFQVDLAPTLALL 333

Query: 340 IGVNYPKNSVGEL-PIAYIDGKESDKLAALYNNARSILEQYLVKQ 383
            GV  PKN+VG L P      ++ ++L AL  N+  +L   L + 
Sbjct: 334 FGVPIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLRLMLAQI 378
>ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]
 gb|AAB93646.1| (AF003137) Hypothetical protein C27A12.9 [Caenorhabditis elegans]
          Length = 905

 Score =  306 bits (777), Expect = 1e-81
 Identities = 80/431 (18%), Positives = 138/431 (31%), Gaps = 62/431 (14%)

Query: 6   RTTLLAVGVLFHLFYLWSIFDIYFISPL-------VHGMSPYQSTPTPPAKRLFLIVGDG 58
           R  L+++ +L  LF   + F +     L        H             +R+ LI+ D 
Sbjct: 6   RILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILILVDA 65

Query: 59  LRADTTFD--KVTHPVSGKTEFL--APFIRSLV-MNNATYGISHTRMPTESRPGHVAMIA 113
           LR D      + T     +  +      I  LV   N + G      PT +     A+  
Sbjct: 66  LRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTT 125

Query: 114 GFYEDVSAVTKGWKSNPV-NFDSFFNQ----STHTYSFGSPDILPMFKDGASDPNKVDTW 168
           G           +  + V + DSF  Q      +    G    L +F +  S     D++
Sbjct: 126 GTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKTAAYDSF 185

Query: 169 MYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDY-EIRQDGNVFFLHLLGCDTAG 227
             +      T          F               L    +  + ++   H LG D  G
Sbjct: 186 DINDLN---TVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCG 242

Query: 228 HSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNN 287
           H + P      D ++ +D  I   I+ +               DHGM++ G HG    N 
Sbjct: 243 HKFGPSHPVMADTLRKMDRIIGQTIETMKS------------DDHGMTSTGDHGGESENE 290

Query: 288 TRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKN 347
            R  ++       K                    +    + Q DI   +S L+G+  P +
Sbjct: 291 IRAGILV---HSKKHQI----------------ILPERPIHQIDIVPTISLLMGLPIPFS 331

Query: 348 SVGELPIAYIDGKESDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHY 407
           ++G + I  +  ++  ++A              V QD V      Y     F E  HSH 
Sbjct: 332 NLGTV-ITQLFTRDLWEIARQMMGF--------VWQDSVGIFAETYAAQKNFGE-LHSHT 381

Query: 408 LEEIETLIQRI 418
           + +  T+ +++
Sbjct: 382 IRDSNTMEEQL 392
>gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melanogaster]
          Length = 880

 Score =  298 bits (758), Expect = 2e-79
 Identities = 84/472 (17%), Positives = 139/472 (28%), Gaps = 76/472 (16%)

Query: 7   TTLLAVGVLFHLF-YLWSIFDIYFISPLVHGMSP------YQSTPTPPAKRLFLIVGDGL 59
            T    G +  L  +  + + +      V    P        + P P      L++ D L
Sbjct: 15  LTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSFVLLLVDAL 74

Query: 60  RADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDV 119
           R D                  P               H  +PT + P   ++  G   + 
Sbjct: 75  RDDF-----------PDATSMPV---AYSRACEKLKLHVDIPTVTMPRLKSITTGTLSNF 120

Query: 120 SAVTKGWKSNPVNFDSFFN----QSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFE 175
             +           DSF +    Q+      G    + +F    +   +     Y     
Sbjct: 121 IDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFY----- 175

Query: 176 DFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSA 235
                  E D  V + L+     S            D ++  LH LG D  GH     S 
Sbjct: 176 --VNDFYEGDRNVTKTLETELERS------------DWSLLILHYLGLDHIGHVEGNASP 221

Query: 236 EYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAW 295
                +K +D+ +  ++D      +      + T DHGM+  G HG   P  T  PL  +
Sbjct: 222 RVPLKLKEMDEVVKKILD----HKSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLY 277

Query: 296 GAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVG-ELPI 354
               +K                           Q D+A  +S L+ V  P  S+G  +P 
Sbjct: 278 YNNCSKTPSASKRY------------------NQIDLAPTLSVLLSVEIPTLSIGCLIPE 319

Query: 355 AYIDGKESDKLAALYNNARSILEQYLVK-QDEVIDSQFFYKEYFKFVEKSHSHYLEEIET 413
                    +L A + NA  +L +  VK   E++    +Y  Y       H   L  +  
Sbjct: 320 MLQSLSLEHQLYAYFYNAHHLLNKARVKFGHEIVHRSDYYTWYQNAT-LLHKKLLRPLRE 378

Query: 414 LIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVG 465
                +    Y   +        M++ L+GL       W  +   V   +  
Sbjct: 379 GDGGGASQVYYQNAKL-----NYMRLQLDGLKVGQ--LWLSVIAAVVLNYTS 423
>ref|NP_495820.1| (NM_063419) Yeast YJ10 like [Caenorhabditis elegans]
 pir||T21487 hypothetical protein F28C6.4 - Caenorhabditis elegans
 emb|CAA92675.1| (Z68315) Similarity to Yeast hypothetical protein YJ10
           (SW:YJ10_YEAST)~cDNA EST yk160e12.5 comes from this
           gene~cDNA EST yk160e12.3 comes from this gene~cDNA EST
           yk317h4.3 comes from this gene~cDNA EST yk317h4.5 comes
           from this gene [Caenorhabditis ele>
          Length = 795

 Score =  297 bits (755), Expect = 5e-79
 Identities = 80/393 (20%), Positives = 136/393 (34%), Gaps = 52/393 (13%)

Query: 2   WNKTRTTLLAVGVLFHLFYLWSIFDIYFISPL----VHGMSPYQSTPTPPAKRLFLIVGD 57
           W      + A  +L + F      DI    P         +   S+      RL  +V D
Sbjct: 59  WISRVLVVCACALLVYSF---VALDITPTPPTEEFGFKDGNQESSSSP----RLVFMVID 111

Query: 58  GLRADTTFDKVTHPVSGKTEFLAPFIRS-LVMNNATYGISHTRMPTESRPGHVAMIAGFY 116
             R                +    F +S +   +A    ++ RMPT + P   A + G  
Sbjct: 112 AFRLSFLTSS---------KSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTL 162

Query: 117 EDVSAVTKGWKSNPVNFDSFFNQ----STHTYSFGSPDILPMFKDGASDPNKVDTWMYDH 172
                V     +  +   ++ ++        + FG    + +          V ++    
Sbjct: 163 PSFGTVLTNLATAEMKTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSF---- 218

Query: 173 TFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRP 232
               F     ++D  V RHLD    N+              +   LH LG D  GHS   
Sbjct: 219 ----FVSDYTDVDNNVTRHLDTELSNT----------NHSWDALILHYLGLDHIGHSLGG 264

Query: 233 YSAEYYDNVKYIDDQIPILIDKVN-KFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTP 291
            S++  + +K +DD I  +   +      D ++  I   DHGM+A GSHG   P+ TR P
Sbjct: 265 SSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVP 324

Query: 292 LVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGE 351
           +V W  G  +   N     D+  +           ++Q D++S +  +  +  P  S G 
Sbjct: 325 VVIWKFGREEGNKNYGNQDDSLKQPPR--------IEQIDVSSTIFDVFNMPIPIESYGI 376

Query: 352 LPIAYIDGKESDKLAALYNNARSILEQYLVKQD 384
             I Y    E +     +N  R I++   +   
Sbjct: 377 SLINYFSDDEEEYFEKQHNQFRRIVQAKHLAIS 409
 Score = 35.7 bits (82), Expect = 3.4
 Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 8/89 (8%)

Query: 777 SVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGA-LLMLKLIIPYGLL--- 832
           SV    L   +FF TGN  S+S+ SL S    L  + P L+G  L++     P   L   
Sbjct: 676 SVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPILVGLQLMLYTFSGPILFLCGC 735

Query: 833 --STCLGILN--LKLNFKDYTISSLIISM 857
             S+C  +LN            S + + +
Sbjct: 736 NASSCTSLLNHLFSYRISSMCTSLICLYI 764
>gb|AAF56711.1| (AE003761) CG13978 gene product [Drosophila melanogaster]
          Length = 475

 Score =  289 bits (734), Expect = 1e-76
 Identities = 67/306 (21%), Positives = 119/306 (37%), Gaps = 29/306 (9%)

Query: 249 PILIDKVNKFFADDKTA-----------FIFTAD-----HGMSAFGSHGDGHPNNTRTPL 292
               DKV  F  +               F++ AD     H      +HG G P    TPL
Sbjct: 172 KWAFDKVENFLRNVDNVREWRNYKPAVFFVYLADMDIAAHRFKPLRAHGSGSPLEVETPL 231

Query: 293 VAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGEL 352
             WGAG+ +   +      N+ E         + V Q  +A LMS LIG+  PKN++  +
Sbjct: 232 FMWGAGVKR---DEIDAEANFPEKPN-----ISQVDQTQLAPLMSSLIGLPPPKNNLALM 283

Query: 353 PIAYIDGKESDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEIE 412
           P+ Y++  +  +  AL+ N   +L Q  +      +   FYK   KF ++ H   +++  
Sbjct: 284 PVGYLNVSDEYQAVALHLNVLQLLSQAEILIGRH-EKAIFYKWLPKF-KELHIGVIDQYA 341

Query: 413 TLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFI 472
                +    N    +A+   +E  ++  + L Y   Y    +    +  ++ W F+  +
Sbjct: 342 AQFDILKSEGN--LTDAMEFCKEYGKLAKKCLTYYNQYYQTPLIVANSMSYMIW-FYCLL 398

Query: 473 IFLKSFILENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIF 532
           + L     +  +  +    +S  +   IGILL  ++  Q  P     YL+ P+       
Sbjct: 399 LQLTRLSKKEKMQRRGFMTVSTLILAMIGILLIAMMELQKVPHIAAFYLILPVGMLIMAQ 458

Query: 533 TNRSVL 538
             R  +
Sbjct: 459 AERPDI 464
 Score =  203 bits (513), Expect = 1e-50
 Identities = 61/230 (26%), Positives = 102/230 (43%), Gaps = 22/230 (9%)

Query: 9   LLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTP----TPPAKRLFLIVGDGLRADTT 64
                ++ H+  + +I + YF   L+  + P ++       PPA RL + V DGLRA T 
Sbjct: 2   WKLQALVVHILLMGAILNTYFQHTLLPNLVPQKTMRELGLEPPADRLVVFVTDGLRAATF 61

Query: 65  FDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTK 124
                  V        P ++ +       GIS T  PT +RPGH+A+ AGF+ED +A   
Sbjct: 62  LANNGSDV--------PDLKDIYRQQGRIGISRTCAPTMTRPGHIAIFAGFHEDPAASLM 113

Query: 125 GWKSNPVNFDSFFNQSTHTYSFGSPDILPMFK--DGASDPNKVDTWMYDHTFEDFTQSSI 182
               NP +FD+ FN+S +   +    I+  F        P + D++M     E       
Sbjct: 114 HLCYNPGDFDTVFNRSRNMIGWAHSYIVGYFVKLSHGGAPLRFDSYMERDLPEKL----- 168

Query: 183 ELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRP 232
             D + F  ++    N  +++  ++   +   VFF++L   D A H ++P
Sbjct: 169 TCDKWAFDKVENFLRN--VDNVREWRNYK-PAVFFVYLADMDIAAHRFKP 215
>ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) biosynthesis; Gpi13p
           [Saccharomyces cerevisiae]
 pir||S64782 probable membrane protein YLL031c - yeast (Saccharomyces
           cerevisiae)
 emb|CAA97480.1| (Z73136) ORF YLL031c [Saccharomyces cerevisiae]
          Length = 1017

 Score =  283 bits (719), Expect = 8e-75
 Identities = 64/391 (16%), Positives = 121/391 (30%), Gaps = 51/391 (13%)

Query: 6   RTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPY--QSTPTPPAKRLFLIVGDGLRADT 63
              +    +L  +   +          ++  +S     S   P   +  ++V D LR D 
Sbjct: 37  ILLVFI-AILQFISIAFFTRGFLLSRHVLDNISSQNETSKLPPRFNKAVILVIDALRFDF 95

Query: 64  TFDKVTHPVSGKTEFLAPFIRSLVMNNATY----------GISHTRMPTESRPGHVAMIA 113
                         +   +  +++    ++                 PT +      +  
Sbjct: 96  AIPVNESHS----NYNLNYHNNILSLYDSFASDKDASSLLLKFIADPPTTTLQRLKGLTT 151

Query: 114 GFYEDVSAVTKGWKSNPVNFDSFFNQ----STHTYSFGSPDILPMFKDGASDPNKVDTWM 169
           G           +    +  D+F  Q    +      G    + +F          D++ 
Sbjct: 152 GSLPTFIDAGSNFDGTVIEEDNFLKQLHLANKTVKFAGDDTWMALF----HPFLSNDSF- 206

Query: 170 YDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHS 229
                         +D  V  +                +  ++ +V   H+LG D  GH 
Sbjct: 207 --PLESLNVWDLDTVDNGVMDYFHDHL-----------QQDKEWDVMIGHMLGIDHVGHK 253

Query: 230 YRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTR 289
           Y P      +    +D  I  ++        DD T  +   DHGM   G+HG    +   
Sbjct: 254 YGPDHFTMREKQIQVDQFIDWILKS-----IDDDTLLVILGDHGMDHTGNHGGDSIDELE 308

Query: 290 TPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSV 349
           + L  +     KP       + NY  N +        V+Q D+ S ++ L+G   P N++
Sbjct: 309 STLFLYS---KKPDMWRLKETSNY--NIDNLGHDYRSVRQIDLVSSLALLMGQPIPFNNL 363

Query: 350 GELPIAYIDGKESDKLAALYNNARSILEQYL 380
           G  PI  I  +   + +   N+A S L+ Y 
Sbjct: 364 G-WPIDEI-ARNDREWSQFVNSAISQLQLYK 392
>gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melanogaster]
          Length = 1077

 Score =  274 bits (694), Expect = 6e-72
 Identities = 55/359 (15%), Positives = 118/359 (32%), Gaps = 53/359 (14%)

Query: 33  LVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTF--DKVTHPVSGKTEFLAPFIRSLVMNN 90
           +   ++   +   P   ++ ++V D L+ +        T P+  + + +   ++ L+  N
Sbjct: 61  IFKDVNASSNLCLPQKSKVIVLVVDALKYEFGLYRANATDPLPYENKLVV--LQELLQQN 118

Query: 91  ---ATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQSTH----T 143
              A         PT +      +  G       +   + S  +N D+  +Q        
Sbjct: 119 PDHARLMRFRADPPTTTLQRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQIVKNDLPV 178

Query: 144 YSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNS 203
              G      ++           ++               +D  + +HL +         
Sbjct: 179 VFLGDSTWTDLYPHRFKRSYSYPSFD--------IFDLDSVDNEILKHLPKELE------ 224

Query: 204 TLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDK 263
                  +D  V   H LG D  GH + P   E    +  +++ I  ++  +     D+ 
Sbjct: 225 ------SKDWQVLVAHFLGVDHCGHKHGPMHEEMARKLGEMNEVIRSVVAAM-----DND 273

Query: 264 TAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIK 323
           T  +   DHGM+A G HG    + T   L A+                 Y      S   
Sbjct: 274 TTLLVMGDHGMTASGDHGGDTDDETNALLFAYS-----------KQHRFYG---NDSGSD 319

Query: 324 RNDVKQADIASLMSYLIGVNYPKNSVGEL---PIAYIDGKESDKLAALYNNARSILEQY 379
              ++Q D+   ++ ++GV  P +++G +    +  +     +K   L  ++    +Q 
Sbjct: 320 SEMLQQIDLVPTLATILGVPIPYSNLGLVNFNIVPDLRVPHLNKFQTLLLHSWQNAQQI 378
>ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thaliana]
 dbj|BAB10512.1| (AB005238) gene_id:MKP11.10~unknown protein [Arabidopsis thaliana]
          Length = 884

 Score =  263 bits (668), Expect = 8e-69
 Identities = 45/334 (13%), Positives = 93/334 (27%), Gaps = 48/334 (14%)

Query: 7   TTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTFD 66
             + A+ +L                     +S      +P +                  
Sbjct: 16  LLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSPCLASPRSN----------------- 58

Query: 67  KVTHPVSGKTEFLAPFIRSLVMNN---ATYGISHTRMPTESRPGHVAMIAGFYEDVSAVT 123
             +             +++L   N   A    +    PT S      +  G       + 
Sbjct: 59  HDSSSEPKPWMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIG 118

Query: 124 KGWKSNPVNFDSFFNQ----STHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQ 179
             + +  +  D+F NQ           G      +F +         ++          +
Sbjct: 119 NSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYPFPSFN--------VK 170

Query: 180 SSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYD 239
               +D     HL                 + D +V   H LG D AGH +   S+   +
Sbjct: 171 DLDTVDNGCIEHL------------FPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPMIN 218

Query: 240 NVKYIDDQIPILIDKVNKF----FADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAW 295
            ++  +  +  +I+ +          + T  I   DHG +  G HG G      T + A 
Sbjct: 219 KLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAM 278

Query: 296 GAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQ 329
               +  +  P   + +  +N +   +  + ++Q
Sbjct: 279 STKKHTTLVPPEFDTSSCKQNKDGKQMCISYIEQ 312
>ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like protein [Arabidopsis
           thaliana]
 pir||T09933 nucleotide pyrophosphatase homolog T16L4.210 - Arabidopsis thaliana
 emb|CAB45330.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79728.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 461

 Score =  257 bits (652), Expect = 5e-67
 Identities = 47/280 (16%), Positives = 89/280 (31%), Gaps = 29/280 (10%)

Query: 8   TLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRL-----FLIVGDGLRAD 62
            +  + +        +         L     P ++    P K+L      +I  DG R  
Sbjct: 14  LIFLLNIFIVATIAAAAAVNAGTKGLDS--RPSKTRRPWPFKKLNKPVVLMISCDGFRFG 71

Query: 63  TTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISH-TRMPTESRPGHVAMIAGFYEDVSA 121
             F           +   P I  L+              PT + P H ++  G Y     
Sbjct: 72  YQF-----------KTDTPNIDLLISGGTEAKHGLIPVFPTMTFPNHYSIATGLYPAYHG 120

Query: 122 VTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQSS 181
           +     ++PV  +  FN+      +      P++    +   K  T+ +  +     +SS
Sbjct: 121 IIMNKFTDPVTGE-VFNKGLQPKWWLGE---PLWVTAVNQGLKAVTYFWPGSEV--LKSS 174

Query: 182 IELDAFVFRHLD-QLFHNSTLNSTL--DYEIRQD-GNVFFLHLLGCDTAGHSYRPYSAEY 237
                    H +  +     ++S L     +  +  ++  L+    D +GH+Y P     
Sbjct: 175 WTCPEGYCPHFNLSVPLEERVDSVLSHFDHLEDEVPDLLMLYFDEPDQSGHNYGPDDPRV 234

Query: 238 YDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAF 277
              V  +D  I  +I  + +    D+   I   DHGM   
Sbjct: 235 TTAVSRVDKMIGRVIKGLKQREIFDEVHVILLGDHGMVTN 274
>dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like protein [Spinacia
           oleracea]
          Length = 479

 Score =  257 bits (652), Expect = 5e-67
 Identities = 51/284 (17%), Positives = 88/284 (30%), Gaps = 30/284 (10%)

Query: 5   TRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQS-TPTPPAKRL--------FLIV 55
               +  +   F        F   F+S         ++   T  A+ L         LI 
Sbjct: 41  KVLLISLLSTTFTAVIAAVSFAFLFLSATSAAAGESKTIKITTTARSLTKLTHPIVILIS 100

Query: 56  GDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISH-TRMPTESRPGHVAMIAG 114
            DG R    F           +   P I  L+ N  +  +      PT + P H +++ G
Sbjct: 101 SDGFRFGYQF-----------KAPTPNIHRLINNGTSAELGLIPVFPTLTFPNHYSIVTG 149

Query: 115 FYEDVSAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTF 174
            Y     +   +  +P+  D F   S     +      P+++  A    K  T+ +  + 
Sbjct: 150 LYPPHHGIINNYFVDPITGDKFSMASHEPKWWLGE---PLWETVAKHGKKAATYFWPGSE 206

Query: 175 EDFTQSSIELDAFVFRHLDQ-LFHNSTLNST--LDYEIRQDGNVFF-LHLLGCDTAGHSY 230
               +   +  +    H +  +     +++          +  VF  L+    D  GH  
Sbjct: 207 V--IKPDWDCPSNYCIHYNGSIPFEERVDTVISYFDLPINEIPVFMTLYFEDPDHQGHQV 264

Query: 231 RPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGM 274
            P   E    V  ID  I  LI  + K    +        DHGM
Sbjct: 265 GPDDPEITQAVINIDKMIGRLIKGLEKRGVFEDVNIFMVGDHGM 308
>gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophosphatase [Arabidopsis
           thaliana]
          Length = 456

 Score =  253 bits (641), Expect = 1e-65
 Identities = 52/282 (18%), Positives = 92/282 (32%), Gaps = 43/282 (15%)

Query: 20  YLWSIFDIYF--------------ISPLVHGMSPYQSTPTPPAKRL-----FLIVGDGLR 60
           +L S F I+F                 L     P ++    P K+L      +I  DG R
Sbjct: 7   FLSSSFLIFFIVATIAAAAAVNAGTKGLDS--RPSKTRRPWPFKKLNKPVVLMISCDGFR 64

Query: 61  ADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISH-TRMPTESRPGHVAMIAGFYEDV 119
               F           +   P I  L+              PT + P H ++  G Y   
Sbjct: 65  FGYQF-----------KTDTPNIDLLISGGTEAKHGLIPVFPTMTFPNHYSIATGLYPAY 113

Query: 120 SAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQ 179
             +     ++PV  +  FN+      +      P++    +   K  T+ +  +     +
Sbjct: 114 HGIIMNKFTDPVTGE-VFNKGLQPKWWLGE---PLWVTAVNQGLKAVTYFWPSSEV--LK 167

Query: 180 SSIELDAFVFRHLD-QLFHNSTLNSTL--DYEIRQD-GNVFFLHLLGCDTAGHSYRPYSA 235
           SS         H +  +     ++S L     +  +  ++  L+    D +GH+Y P   
Sbjct: 168 SSWTCPEGYCPHFNLSVPLEERVDSVLSHFDHLEDEVPDLLMLYFDEPDQSGHNYGPDDP 227

Query: 236 EYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAF 277
                V  +D  I  +I  + +    D+   I   DHGM   
Sbjct: 228 RVTTAVSRVDKMIGRVIKGLKQREIFDEVHVILLGDHGMVTN 269
>ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09932 nucleotide pyrophosphatase homolog T16L4.200 - Arabidopsis thaliana
 emb|CAB45329.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79727.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 457

 Score =  248 bits (628), Expect = 3e-64
 Identities = 43/254 (16%), Positives = 77/254 (29%), Gaps = 28/254 (11%)

Query: 35  HGMSPYQSTPTPPAKRL-----FLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMN 89
                       P K+L      LI  DG R    F           +   P I  L+  
Sbjct: 36  SDSPSSYVRRPQPPKKLNKPVVLLISCDGFRFGYQF-----------KTETPNIDLLISR 84

Query: 90  NATYGISH-TRMPTESRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQSTHTYSFGS 148
                       PT + P H ++  G Y     +     ++PV+ +  FN++ +   +  
Sbjct: 85  GTEAKTGLIPVFPTMTFPNHYSIATGLYPASHGIIMNKFTDPVSGE-LFNRNLNPKWWLG 143

Query: 149 PDILPMFKDGASDPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQ--LFHNSTLNSTL- 205
               P++    +      T+ +     D  + S        +      +     +++ L 
Sbjct: 144 E---PLWVTAVNQGLMAATYFWPG--ADVHKGSWNCPKGFCKAPYNVSVPLEERVDTILN 198

Query: 206 -DYEIRQD-GNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDK 263
                 ++  +   L+    D  GH Y P      + V  +D  I  +I  + K      
Sbjct: 199 YFDLPEREIPDFMALYFDEPDIQGHEYGPDDPRVTEAVSKVDKMIGRIIMGLEKRKVFSD 258

Query: 264 TAFIFTADHGMSAF 277
              I   DHGM   
Sbjct: 259 VHVILLGDHGMVTN 272
>ref|NP_476445.1| (NM_057104) phosphodiesterase I/nucleotide pyrophosphatase 2;
           phosphodiesterase I/nucleotide pyrophosphatase 2
           (autotaxin) [Rattus norvegicus]
 pir||A55453 plasma cell membrane glycoprotein PC-1, brain specific - rat
 dbj|BAA05910.1| (D28560) phosphodiesterase I [Rattus norvegicus]
          Length = 885

 Score =  244 bits (617), Expect = 6e-63
 Identities = 42/243 (17%), Positives = 76/243 (30%), Gaps = 38/243 (15%)

Query: 39  PYQST--PTPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGIS 96
             +      PP   L +   DG RA             K   + P I  L         +
Sbjct: 152 SSECLQVCPPP---LIIFSVDGFRASYM---------KKGSKVMPNIEKLRSCGTHVPYT 199

Query: 97  HTRMPTESRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQST---HTYSFGSPDILP 153
               PT++ P    +  G Y +   +      +PV   SF  +     +   +G     P
Sbjct: 200 RPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDASFHLRGREKFNHRWWGGQ---P 256

Query: 154 MFKDGASDPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDG 213
           ++        +  T+ +  +                  +       T+   L     +  
Sbjct: 257 LWITATKQGVRAGTFFWSVS------------------IPHERRILTILQWLSLPDNERP 298

Query: 214 NVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHG 273
           +V+  +    D +GH Y P+  E  + ++ ID  +  L+D + +         IF  DHG
Sbjct: 299 SVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHG 358

Query: 274 MSA 276
           M  
Sbjct: 359 MED 361
>ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09931 nucleotide pyrophosphatase homolog T16L4.190 - Arabidopsis thaliana
 emb|CAB45328.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79726.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 496

 Score =  242 bits (614), Expect = 2e-62
 Identities = 50/286 (17%), Positives = 91/286 (31%), Gaps = 36/286 (12%)

Query: 9   LLAVGVLFHLFYLWSIFDIYFISPLV--HGMSPYQSTPTPPAKR-------------LFL 53
           +    +L     L +     F+        +S  Q + +P   R             + L
Sbjct: 52  IFTSLLLVTCIALSAASAFAFLFFSSQKPVLSLNQISKSPAFDRSVARPLKKLDKPVVLL 111

Query: 54  IVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISH-TRMPTESRPGHVAMI 112
           I  DG R    F           +   P I  L+ N            PT + P H +++
Sbjct: 112 ISSDGFRFGYQF-----------KTKLPSIHRLIANGTEAETGLIPVFPTLTFPNHYSIV 160

Query: 113 AGFYEDVSAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDH 172
            G Y     +      +P   + F   S     +      P+++   +   K  T+ +  
Sbjct: 161 TGLYPAYHGIINNHFVDPETGNVFTMASHEPEWWLGE---PLWETVVNQGLKAATYFWPG 217

Query: 173 TFEDFTQSSIELDAFVFRHLDQ-LFHNSTLNSTL--DYEIRQDGNVFF-LHLLGCDTAGH 228
           +     + S      + ++ +  +  +  +++ L        +   F  L+    D  GH
Sbjct: 218 SEVH--KGSWNCPQGLCQNYNGSVPFDDRVDTILSYFDLPSNEIPSFMTLYFEDPDHQGH 275

Query: 229 SYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGM 274
              P   +  + V  ID  I  LID + K    +    I   DHGM
Sbjct: 276 QVGPDDPQITEAVVNIDRLIGRLIDGLEKRGIFEDVTMIMVGDHGM 321
>pir||T03293 nucleotide pyrophosphatase homolog - rice
 gb|AAA67067.1| (U25430) nucleotide pyrophosphatase precursor [Oryza sativa]
 gb|AAF65458.1|AF245483_1 (AF245483) OSE4 [Oryza sativa]
 dbj|BAB56086.1| (AP003244) nucleotide pyrophosphatase homolog [Oryza sativa]
          Length = 479

 Score =  242 bits (613), Expect = 2e-62
 Identities = 52/281 (18%), Positives = 88/281 (30%), Gaps = 31/281 (11%)

Query: 4   KTRTTLLAVGVLFHLFYLWSIFDIYFISPLV-----HGMSPYQSTPTPPAKRLFLIVGDG 58
                LL   +     YL     I   +PL         +  Q     P   + LI  DG
Sbjct: 45  SRLHLLLTAALAVATSYL---LLILPRTPLSAAPAPAAAARAQVKLEKPV--VILISSDG 99

Query: 59  LRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISH-TRMPTESRPGHVAMIAGFYE 117
            R                +   P I  L+ N  +         PT + P H ++  G Y 
Sbjct: 100 FRFGYQ-----------HKAATPHIHRLIGNGTSAATGLVPIFPTLTFPNHYSIATGLYP 148

Query: 118 DVSAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDF 177
               +   +  +P++ D F   S     +      P++   A    +  T+ +  +    
Sbjct: 149 SSHGIINNYFPDPISGDYFTMSSHEPKWWLGE---PLWVTAADQGIQAATYFWPGSEVK- 204

Query: 178 TQSSIELDAFVFRHLDQ-LFHNSTLNSTL--DYEIRQDGNVFF-LHLLGCDTAGHSYRPY 233
            + S +      RH +  +     +++ L        +   F  L+    D  GH   P 
Sbjct: 205 -KGSWDCPDKYCRHYNGSVPFEERVDAILGYFDLPSDEMPQFLTLYFEDPDHQGHQVGPD 263

Query: 234 SAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGM 274
                + V  ID+ I  LI  + +    +    I   DHGM
Sbjct: 264 DPAITEAVVRIDEMIGRLIAGLEERGVFEDVNVILVGDHGM 304
>gb|AAH03264.1|AAH03264 (BC003264) ectonucleotide pyrophosphatase/phosphodiesterase 2 [Mus
           musculus]
          Length = 862

 Score =  242 bits (612), Expect = 2e-62
 Identities = 40/236 (16%), Positives = 73/236 (29%), Gaps = 37/236 (15%)

Query: 44  PTPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTE 103
             P    L +   DG RA             K   + P I  L              PT+
Sbjct: 162 RPP----LIIFSVDGFRASYM---------KKGSKVMPNIEKLRSCGTHAPYMRPVYPTK 208

Query: 104 SRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQST---HTYSFGSPDILPMFKDGAS 160
           + P    +  G Y +   +      +PV   +F  +     +   +G     P++     
Sbjct: 209 TFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQ---PLWITATK 265

Query: 161 DPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHL 220
              +  T+ +  +                  +       T+   L     +  +V+  + 
Sbjct: 266 QGVRAGTFFWSVS------------------IPHERRILTILQWLSLPDNERPSVYAFYS 307

Query: 221 LGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSA 276
              D +GH Y P+  E  + ++ ID  +  L+D + +         IF  DHGM  
Sbjct: 308 EQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMED 363
>ref|NP_056559.1| (NM_015744) phosphodiesterase I/nucleotide pyrophosphatase 2 [Mus
           musculus]
 gb|AAD46480.1|AF123542_1 (AF123542) phosphodiesterase I/nucleotide pyrophosphatase [Mus
           musculus]
          Length = 862

 Score =  242 bits (612), Expect = 3e-62
 Identities = 40/236 (16%), Positives = 73/236 (29%), Gaps = 37/236 (15%)

Query: 44  PTPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTE 103
             P    L +   DG RA             K   + P I  L              PT+
Sbjct: 162 RPP----LIIFSVDGFRASYM---------KKGSKVMPNIEKLRSCGTHAPYMRPVYPTK 208

Query: 104 SRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQST---HTYSFGSPDILPMFKDGAS 160
           + P    +  G Y +   +      +PV   +F  +     +   +G     P++     
Sbjct: 209 TFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQ---PLWITATK 265

Query: 161 DPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHL 220
              +  T+ +  +                  +       T+   L     +  +V+  + 
Sbjct: 266 QGVRAGTFFWSVS------------------IPHERRILTILQWLSLPDNERPSVYAFYS 307

Query: 221 LGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSA 276
              D +GH Y P+  E  + ++ ID  +  L+D + +         IF  DHGM  
Sbjct: 308 EQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMED 363
>dbj|BAA08260.1| (D45421) phosphodiesterase I alpha [Homo sapiens]
          Length = 863

 Score =  239 bits (605), Expect = 2e-61
 Identities = 41/236 (17%), Positives = 72/236 (30%), Gaps = 37/236 (15%)

Query: 44  PTPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTE 103
             P    L +   DG RA             K   + P I  L              PT+
Sbjct: 163 RPP----LIIFSVDGFRASYM---------KKGSKVMPNIEKLRSCGTHSPYMRPVYPTK 209

Query: 104 SRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQST---HTYSFGSPDILPMFKDGAS 160
           + P    +  G Y +   +      +PV   +F  +     +   +G     P++     
Sbjct: 210 TFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQ---PLWITATK 266

Query: 161 DPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHL 220
              K  T+ +                     +       T+   L     +  +V+  + 
Sbjct: 267 QGVKAGTFFWSVV------------------IPHERRILTILQWLTLPDHERPSVYAFYS 308

Query: 221 LGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSA 276
              D +GH Y P+  E  + ++ ID  +  L+D + +         IF  DHGM  
Sbjct: 309 EQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMED 364
>ref|NP_006200.1| (NM_006209) ectonucleotide pyrophosphatase/phosphodiesterase 2
           (autotaxin); Phosphodiesterase I/nucleotide
           pyrophosphatase 2; autotaxin; phosphodiesterase
           I/nucleotide pyrophosphatase 2 (autotaxin) [Homo
           sapiens]
 gb|AAB00855.1| (L46720) autotaxin-t [Homo sapiens]
          Length = 863

 Score =  238 bits (604), Expect = 2e-61
 Identities = 41/236 (17%), Positives = 72/236 (30%), Gaps = 37/236 (15%)

Query: 44  PTPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTE 103
             P    L +   DG RA             K   + P I  L              PT+
Sbjct: 163 RPP----LIIFSVDGFRASYM---------KKGSKVMPNIEKLRSCGTHSPYMRPVYPTK 209

Query: 104 SRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQST---HTYSFGSPDILPMFKDGAS 160
           + P    +  G Y +   +      +PV   +F  +     +   +G     P++     
Sbjct: 210 TFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQ---PLWITATK 266

Query: 161 DPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHL 220
              K  T+ +                     +       T+   L     +  +V+  + 
Sbjct: 267 QGVKAGTFFWSVV------------------IPHERRILTILQWLTLPDHERPSVYAFYS 308

Query: 221 LGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSA 276
              D +GH Y P+  E  + ++ ID  +  L+D + +         IF  DHGM  
Sbjct: 309 EQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMED 364
>pir||T33724 hypothetical protein - Zymomonas mobilis
 gb|AAC70363.1| (AF086791) unknown [Zymomonas mobilis]
          Length = 429

 Score =  235 bits (595), Expect = 3e-60
 Identities = 59/291 (20%), Positives = 98/291 (33%), Gaps = 43/291 (14%)

Query: 3   NKTRTTLL--AVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLR 60
            K R   +   + +L     L  +     I+   H  +  ++        L LI  DG R
Sbjct: 8   LKKRKPWISGILSLLLGCAGLSVVHSDA-IAATAHVTAQSKTP-------LILISIDGFR 59

Query: 61  ADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVS 120
           AD                L P + SL  N +   + H   P+ + P H  ++ G Y D  
Sbjct: 60  ADY-----------IKRGLTPNLVSLAENGSYAKVMHPSFPSITFPNHYTLVTGLYPDHH 108

Query: 121 AVTKGWKSNP-VNFDSFFNQS-------THTYSFGSPDILPMFKDGASDPNKVDTWMYDH 172
            +      +  +  DS F  S          +  G     P++           T  +  
Sbjct: 109 GIVGNNMDDAHITPDSHFKMSDHQAATDRRWWDEGE----PLWVTAEKQGVVSATMFWPG 164

Query: 173 TFEDFTQSSIELDAFVFRHLD-QLFHNSTLNSTLDYEIRQDG--NVFF-LHLLGCDTAGH 228
           +  D     +  + +  R  D  +  +  ++    +          F  L+    D AGH
Sbjct: 165 SEADI--EGVRPEMW--RQFDSHVPFSERVDQVFSWLAYPKKKRPQFITLYFENVDHAGH 220

Query: 229 SYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGS 279
            Y P S E  DN+  ID  I  L+  + +     K   +  +DHGM+A  S
Sbjct: 221 LYGPDSQEVNDNLVKIDQTIGQLVQGLKQRGI--KANLVIVSDHGMAATSS 269
>ref|NP_299876.1| (NC_002488) phosphodiesterase-nucleotide pyrophosphatase precursor
           [Xylella fastidiosa 9a5c]
 pir||B82537 phosphodiesterase-nucleotide pyrophosphatase precursor XF2599
           [imported] - Xylella fastidiosa (strain 9a5c)
 gb|AAF85396.1|AE004067_3 (AE004067) phosphodiesterase-nucleotide pyrophosphatase precursor
           [Xylella fastidiosa 9a5c]
          Length = 433

 Score =  234 bits (593), Expect = 5e-60
 Identities = 50/288 (17%), Positives = 95/288 (32%), Gaps = 37/288 (12%)

Query: 1   MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLR 60
           M      ++    +L     + +  +I  I+   H           P  +L LI+ DGLR
Sbjct: 1   MMIARPLSIFIGTLLLAACSIPTRLNIPTIAITAH-----------PKYKLLLILIDGLR 49

Query: 61  ADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVS 120
           AD                 AP +  L  +           P  + P    +I G   D  
Sbjct: 50  ADAL-----------EHGQAPQLARLASDGVHALWMTPSYPALTLPNAYTLITGLRPDHH 98

Query: 121 AVTKGWKSNPVNFDSFFNQSTHTY----SFGSPDILPMFKDGASDPNKVDTWMYDHTFED 176
            +      +P+    F +++         +G     P++           T+++  +   
Sbjct: 99  GIVHNTMEDPLLGA-FESENQEAISDGRWWGGE---PIWVSAEHAGIHSATFLWPGSEAS 154

Query: 177 FTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGN---VFFLHLLGCDTAGHSYRPY 233
                     +   +   +  ++ +   L +   +  +   +  L     +TAG+S+ P 
Sbjct: 155 IA--GTRPSRWYAYN-KHISADTQITQALRWLNERGPDAPRLVILRFEQVNTAGNSFGPD 211

Query: 234 SAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAF-GSH 280
           S +Y   V  ID  I  LID + +      T  I  +D G++   G H
Sbjct: 212 SPQYAAAVHMIDSAIGRLIDSLRQHGKLTDTDVIVVSDQGIAPIPGDH 259
>dbj|BAA87261.1| (AB027957) Hypothetical protein [Schizosaccharomyces pombe]
          Length = 179

 Score =  232 bits (587), Expect = 2e-59
 Identities = 90/179 (50%), Positives = 123/179 (68%), Gaps = 1/179 (0%)

Query: 210 RQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDK-TAFIF 268
            +D  VFFLHLLG DT GH+  P S EY +N++YID +I  L+DK+N ++ +D  ++++F
Sbjct: 1   HRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVF 60

Query: 269 TADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVK 328
           TADHGMS FGSHGDG+ +NTRTP++AWGAG+  P H      D Y+  W L+ IKR D++
Sbjct: 61  TADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQ 120

Query: 329 QADIASLMSYLIGVNYPKNSVGELPIAYIDGKESDKLAALYNNARSILEQYLVKQDEVI 387
           QADIA+LMSYL+G+N+P NSVG++P+ Y+D     K      NA  I EQY +K     
Sbjct: 121 QADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRKAEVALMNALEIGEQYNLKSASKD 179
>pir||T40657 probable phophodiesterase-nucleotide pyrophosp hatase precursor -
           fission yeast (Schizosaccharomyces pombe)
 emb|CAA22177.1| (AL034352) putative nucleotide pyrophosphatase precursor
           [Schizosaccharomyces pombe]
          Length = 485

 Score =  227 bits (575), Expect = 5e-58
 Identities = 53/295 (17%), Positives = 95/295 (31%), Gaps = 42/295 (14%)

Query: 2   WNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKR-LFLIVGDGLR 60
           W K     +A   +  +  L  +    F + +   +    +  T   +  + +I  DG R
Sbjct: 26  WAKRSGLAIAAICILGILILAIVKLFCFKAIIFPIVGGSFNNGTNVFQSTVIVISLDGFR 85

Query: 61  ADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVS 120
           AD  +               P + SL   N          P+ + P H  ++ G Y +  
Sbjct: 86  ADYLY-----------RGFTPNLLSLAERNVHVPFLIPSFPSITFPNHYTIVTGLYPESH 134

Query: 121 AVTKGWKSNPVNFDSFF------NQSTHTYSFGSPDILPM------FKDGASDPNKVDTW 168
            +      +PV    F       N+    +  G P  +                N+V+  
Sbjct: 135 GIVSNNFFDPVTGKQFVNSMPECNKDPTWWDKGEPIWVNAERNNVRSAVHMWPGNEVENH 194

Query: 169 MYDHTFED-FTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGN---VFFLHLLGCD 224
            Y  T+ D F   +                    +  L++    D +   +   +    D
Sbjct: 195 GYRPTYSDGFNFDTT--------------LREKKDRILEWLDLPDKDRPQLLLAYAPHVD 240

Query: 225 TAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGS 279
             GH++ P S E    ++ +D  I  LI+ + K   D     IF +DHGM+    
Sbjct: 241 MVGHAFGPDSPELNIIIQEVDIVIGELIEGLKKRNIDKHVNIIFLSDHGMAPTSD 295
>ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo sapiens]
 gb|AAH13987.1|AAH13987 (BC013987) Similar to hypothetical protein MGC3079 [Homo sapiens]
          Length = 454

 Score =  224 bits (568), Expect = 4e-57
 Identities = 41/235 (17%), Positives = 79/235 (33%), Gaps = 35/235 (14%)

Query: 208 EIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFI 267
               + +V   H LG D  GH + P+  E    +  +D  I  L++++        T  +
Sbjct: 1   MDSGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLEN-----DTLLV 55

Query: 268 FTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDV 327
              DHGM+  G HG          L  +      P   P                +   +
Sbjct: 56  VAGDHGMTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPE---------------EPEVI 100

Query: 328 KQADIASLMSYLIGVNYPKNSVGELPIAYIDG--------KESDKLAALYNNARSILEQY 379
            Q  +   ++ L+G+  P  ++GE+      G            + +AL+ NA+ +    
Sbjct: 101 PQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFL 160

Query: 380 LV--KQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISEGENYLEQEAITL 432
                  + + ++  ++    F + S      + + L+Q     E  L      L
Sbjct: 161 HTYSAATQDLQAKELHQLQNLFSKASA-----DYQWLLQSPKGAEATLPTVIAEL 210
>ref|NP_116023.1| (NM_032634) hypothetical protein MGC3079 [Homo sapiens]
 gb|AAH01030.1|AAH01030 (BC001030) Similar to phosphatidylinositol glycan, class O [Homo
           sapiens]
          Length = 454

 Score =  217 bits (549), Expect = 6e-55
 Identities = 41/235 (17%), Positives = 79/235 (33%), Gaps = 35/235 (14%)

Query: 208 EIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFI 267
               +  V   H+LG D  GH + P+  E    +  +D  I  L++++        T  +
Sbjct: 1   MDSGEWEVSNQHVLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLEN-----DTLLV 55

Query: 268 FTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDV 327
              DHGM+  G HG          L  +      P   P                +   +
Sbjct: 56  VAGDHGMTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPE---------------EPEVI 100

Query: 328 KQADIASLMSYLIGVNYPKNSVGELPIAYIDG--------KESDKLAALYNNARSILEQY 379
            Q  +   ++ L+G+  P  ++GE+      G            + +AL+ NA+ +    
Sbjct: 101 PQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFL 160

Query: 380 LV--KQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISEGENYLEQEAITL 432
                  + + ++  ++    F + S      + + L+Q     E  L      L
Sbjct: 161 HTYSAATQDLQAKELHQLQNLFSKASA-----DYQWLLQSPKGAEATLPTVIAEL 210
>ref|NP_055751.1| (NM_014936) ectonucleotide pyrophosphatase/phosphodiesterase 4
           (putative function); KIAA0879 protein [Homo sapiens]
 dbj|BAA74902.1| (AB020686) KIAA0879 protein [Homo sapiens]
 emb|CAB56567.1| (AL035701) dJ8B1.2 (KIAA0879 protein) [Homo sapiens]
 gb|AAH18054.1|AAH18054 (BC018054) ectonucleotide pyrophosphatase/phosphodiesterase 4
           (putative function) [Homo sapiens]
          Length = 453

 Score =  209 bits (529), Expect = 2e-52
 Identities = 51/256 (19%), Positives = 94/256 (35%), Gaps = 23/256 (8%)

Query: 25  FDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIR 84
             I   S L+ G     S+  PP  +L L+  DG RAD               +  P ++
Sbjct: 4   LVILLFSGLITGFRSDSSSSLPP--KLLLVSFDGFRADYL-----------KNYEFPHLQ 50

Query: 85  SLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQSTHTY 144
           + +              T++ P H +++ G YE+   +      + V    F + +    
Sbjct: 51  NFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDAVTKKHFSDSNDKDP 110

Query: 145 SFGSPDILPMFKD-GASDPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLD-QLFHNSTLN 202
            + +   +P++      +       M+  T       +I   +  F + +  +     LN
Sbjct: 111 FWWNEA-VPIWVTNQLQENRSSAAAMWPGTDVPI-HDTI---SSYFMNYNSSVSFEERLN 165

Query: 203 STLDYEIRQDGNVFF--LHLLGCDTAGHSYRPYSAE-YYDNVKYIDDQIPILIDKVNKFF 259
           +   +    +  V F  L+    D +GH Y P   E     +K IDD I  L+ ++    
Sbjct: 166 NITMWLNNSNPPVTFATLYWEEPDASGHKYGPEDKENMSRVLKKIDDLIGDLVQRLKMLG 225

Query: 260 ADDKTAFIFTADHGMS 275
             +    I T+DHGM+
Sbjct: 226 LWENLNVIITSDHGMT 241
CPU time:   291.22 user secs.	    3.30 sys. secs	  294.52 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.316    0.180    0.488 

Gapped
Lambda     K      H
   0.270   0.0633    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 684237713
Number of Sequences: 887402
Number of extensions: 40361767
Number of successful extensions: 190097
Number of sequences better than 10.0: 2529
Number of HSP's better than 10.0 without gapping: 232
Number of HSP's successfully gapped in prelim test: 2335
Number of HSP's that attempted gapping in prelim test: 184854
Number of HSP's gapped (non-prelim): 5837
length of query: 919
length of database: 277,845,442
effective HSP length: 55
effective length of query: 864
effective length of database: 229,038,332
effective search space: 197889118848
effective search space used: 197889118848
T: 11
A: 40
X1: 15 ( 6.8 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.7 bits)
S2: 78 (34.4 bits)