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GPI Anchor Biosynthesis Report: AAF59557.2 (PIG-N family, Caenorhabditis elegans)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 
         (929 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Results of PSI-Blast iteration 5

Distribution of 54 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)

gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caeno... 1032 0.0
ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class ... 994 0.0
ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class ... 990 0.0
pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragme... 860 0.0
pir||T40715 hypothetical protein SPBC839.08c - fission yeast (S... 833 0.0
gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melano... 827 0.0
gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melano... 814 0.0
dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N sh... 799 0.0
gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinosito... 793 0.0
ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; ... 786 0.0
gb|AAF54657.1| (AE003692) CG6790 gene product [Drosophila melano... 746 0.0
ref|XP_082200.1| (XM_082200) CG6790 [Drosophila melanogaster] 575 e-162
ref|NP_491098.1| (NM_058697) M01B12.2.p [Caenorhabditis elegans]... 543 e-153
ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan... 537 e-151
dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [M... 482 e-134
ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans] 470 e-131
gb|AAF54658.1| (AE003692) CG5342 gene product [Drosophila melano... 447 e-124
ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) ... 429 e-118
pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast (... 421 e-116
dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:13516... 397 e-109
gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melano... 351 3e-95
gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarr... 330 7e-89
pir||T02245 hypothetical protein P1.11659_3 - human >gi|2984587|... 330 9e-89
ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involv... 328 3e-88
ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class ... 313 8e-84
ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thalia... 313 1e-83
gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melan... 288 3e-76
ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]... 285 3e-75
pir||A27410 plasma cell membrane glycoprotein PC-1 - mouse 257 5e-67
ref|NP_032839.2| (NM_008813) phosphodiesterase I/nucleotide pyro... 257 6e-67
gb|AAK84174.1|AF339910_1 (AF339910) ectonucleotide pyrophosphata... 257 6e-67
sp|P06802|PC1_MOUSE Ectonucleotide pyrophosphatase/phosphodieste... 255 2e-66
ref|NP_445987.1| (NM_053535) ectonucleotide pyrophosphatase/phos... 255 2e-66
gb|AAL26912.1| (AF320054) ecto-nucleotide pyrophosphatase [Rattu... 255 2e-66
dbj|BAA02053.1| (D12485) The first in-frame ATG codon is located... 255 3e-66
gb|AAK69653.1|AF340185_1 (AF340185) ecto-nucleotide pyrophosphat... 254 3e-66
pir||A39216 plasma cell membrane glycoprotein PC-1 - human >gi|7... 254 3e-66
ref|NP_006199.1| (NM_006208) ectonucleotide pyrophosphatase/phos... 252 2e-65
emb|CAB99365.1| (AL117378) dJ131F15.2 (phosphodiesterase I/nucle... 251 3e-65
gb|AAH03264.1|AAH03264 (BC003264) ectonucleotide pyrophosphatase... 238 3e-61
gb|AAF56711.1| (AE003761) CG13978 gene product [Drosophila melan... 238 4e-61
dbj|BAA08260.1| (D45421) phosphodiesterase I alpha [Homo sapiens] 236 1e-60
ref|NP_006200.1| (NM_006209) ectonucleotide pyrophosphatase/phos... 236 1e-60
ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thalia... 232 2e-59
ref|NP_476445.1| (NM_057104) phosphodiesterase I/nucleotide pyro... 228 3e-58
ref|NP_281901.1| (NC_002163) hypothetical protein Cj0729 [Campyl... 219 1e-55
dbj|BAB17014.1| (AB050262) hypothetical protein [Macaca fascicul... 216 1e-54
Alignments
>gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caenorhabditis elegans]
          Length = 929

 Score = 1032 bits (2640), Expect = 0.0
 Identities = 929/929 (100%), Positives = 929/929 (100%)

Query: 1   MSWKFLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDT 60
           MSWKFLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDT
Sbjct: 1   MSWKFLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDT 60

Query: 61  FNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPV 120
           FNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPV
Sbjct: 61  FNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPV 120

Query: 121 QFDSVFNRSSYSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASNLDKWVFEHFEN 180
           QFDSVFNRSSYSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASNLDKWVFEHFEN
Sbjct: 121 QFDSVFNRSSYSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASNLDKWVFEHFEN 180

Query: 181 FLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHL 240
           FLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHL
Sbjct: 181 FLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHL 240

Query: 241 VDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGGPKLDLNQIDLA 300
           VDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGGPKLDLNQIDLA
Sbjct: 241 VDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGGPKLDLNQIDLA 300

Query: 301 PLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEANFKQLKEQIIFLKNAKSRRLWF 360
           PLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEANFKQLKEQIIFLKNAKSRRLWF
Sbjct: 301 PLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEANFKQLKEQIIFLKNAKSRRLWF 360

Query: 361 RQFEKFGDKAMESLRTTLAQLGRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAV 420
           RQFEKFGDKAMESLRTTLAQLGRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAV
Sbjct: 361 RQFEKFGDKAMESLRTTLAQLGRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAV 420

Query: 421 SCSFVAWIALVVSFLHNSTSKENLSLLVPHHLFIIPLACSLLFTAYCSLSMTQTIYIILP 480
           SCSFVAWIALVVSFLHNSTSKENLSLLVPHHLFIIPLACSLLFTAYCSLSMTQTIYIILP
Sbjct: 421 SCSFVAWIALVVSFLHNSTSKENLSLLVPHHLFIIPLACSLLFTAYCSLSMTQTIYIILP 480

Query: 481 IYLISILENHSKLTQRIREHVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLT 540
           IYLISILENHSKLTQRIREHVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLT
Sbjct: 481 IYLISILENHSKLTQRIREHVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLT 540

Query: 541 FMDRAFLAAVFVLLMALPQFYSHPIVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCIL 600
           FMDRAFLAAVFVLLMALPQFYSHPIVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCIL
Sbjct: 541 FMDRAFLAAVFVLLMALPQFYSHPIVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCIL 600

Query: 601 SPIITAFLCHRLSRRSCLTRIQRMLELMIYVQSATAFMIAVVNYGFEKVKKLIQNNWKKK 660
           SPIITAFLCHRLSRRSCLTRIQRMLELMIYVQSATAFMIAVVNYGFEKVKKLIQNNWKKK
Sbjct: 601 SPIITAFLCHRLSRRSCLTRIQRMLELMIYVQSATAFMIAVVNYGFEKVKKLIQNNWKKK 660

Query: 661 KSNSKSSQSLQPPSIARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSIS 720
           KSNSKSSQSLQPPSIARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSIS
Sbjct: 661 KSNSKSSQSLQPPSIARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSIS 720

Query: 721 YESLFMLIFLVLLTLFVRFEFGHLSDVELLQLKVDSTKISTGEYVELRRTVVCVSFVLCP 780
           YESLFMLIFLVLLTLFVRFEFGHLSDVELLQLKVDSTKISTGEYVELRRTVVCVSFVLCP
Sbjct: 721 YESLFMLIFLVLLTLFVRFEFGHLSDVELLQLKVDSTKISTGEYVELRRTVVCVSFVLCP 780

Query: 781 LFGTGNFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQESI 840
           LFGTGNFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQESI
Sbjct: 781 LFGTGNFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQESI 840

Query: 841 QRLCCFSLIFTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSMCISLALLLLLSISSHLMA 900
           QRLCCFSLIFTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSMCISLALLLLLSISSHLMA
Sbjct: 841 QRLCCFSLIFTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSMCISLALLLLLSISSHLMA 900

Query: 901 FEFRKFPGKRNHQEIESISSRKLSDDESA 929
           FEFRKFPGKRNHQEIESISSRKLSDDESA
Sbjct: 901 FEFRKFPGKRNHQEIESISSRKLSDDESA 929
>ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class N [Mus musculus]
 dbj|BAA82619.1| (AB030279) phosphatidylinositolglycan class N [Mus musculus]
          Length = 931

 Score =  994 bits (2544), Expect = 0.0
 Identities = 322/968 (33%), Positives = 503/968 (51%), Gaps = 102/968 (10%)

Query: 5   FLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDTFNK- 63
           F    + +H V   SIFD+Y+TSPLVHG+ PQF      PAKR+ +  ADGLR DT  + 
Sbjct: 4   FFALGLLIHFVFFVSIFDIYFTSPLVHGMTPQFT-PLPPPAKRLVLFVADGLRADTLYEL 62

Query: 64  ---YPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPV 120
                 ++P++ +++   +G +G+S + +PTESRPGHVA+ AG  ED+SAVAKGWK+NPV
Sbjct: 63  DEDGNSRAPFIRNVI-MHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121

Query: 121 QFDSVFNRSSYSWMWGSPDIVNLFDDLPNAE---SFSYSADEEDFASKDASNLDKWVFEH 177
           +FDS+FN S Y+W WGSPDI+ +F    + +   ++SY A  EDF + DA+ LD WVF+ 
Sbjct: 122 EFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWVFDK 181

Query: 178 FENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKV 237
            ++F + A+ +++L  K+ E+K +FFLHLLG+DTNGH ++P SR+Y DNIK VD G++++
Sbjct: 182 VKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIKKVDDGVKEI 241

Query: 238 QHLVDAFFGDH-KTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQG-------- 288
             +   F+GD  KTA++FTSDHGMTDWGSHGAG   E LTPFV WGAG+K          
Sbjct: 242 VSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQY 301

Query: 289 ------------GPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAI 336
                         + D+NQ D+APL+++LIG P P+NS+GILPV  +N+ G  ++ +++
Sbjct: 302 DDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGL-FKAESM 360

Query: 337 EANFKQLKEQII---FLKNAKSRRLWFRQFEKFGDKAMESLRTTLAQLGRDRRFSVATSL 393
             N  Q+ EQ       K   +    F  F+   D     +        +  +F    SL
Sbjct: 361 FTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFDEVVSL 420

Query: 394 FADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIAL----VVSFLHNSTSKENLSLLVP 449
             +   L    + +YH YDR  LG  V+  FV W++     ++    N           P
Sbjct: 421 CEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSNIPKGTRKEGKKP 480

Query: 450 HHLFIIPLACSLL----FTAYCSLSMTQTIYIILPIYLISILENHSKLTQRIREHVKALS 505
           H L +     + +    F    +   T  +Y +LP+ +   +    ++ Q +   V++L 
Sbjct: 481 HCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVIQDL---VESLL 537

Query: 506 AQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAVFVLLMALP---QFYS 562
             P           FV   L    F++ I + VL+F  R  L A  ++    P   Q ++
Sbjct: 538 TFPR--------SHFVAYLL---VFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWT 586

Query: 563 HPIVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFLCHRLSRRSCLTRIQ 622
              ++    +W    L+L +FP +P VG   ++ L + +     FL   LS     T  +
Sbjct: 587 RAKIT--FLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGA----GFLVLLLSLAVVTTLGK 640

Query: 623 RMLELM--------IYVQSATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSLQPPS 674
           R ++L+        + + S    M  V +     +KK                     P 
Sbjct: 641 RNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGL------------------PL 682

Query: 675 IARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFLVLLT 734
           + + +SW ++  S++AP LL+   L  RL +  L     Y LLS  YE+LF L+   L+ 
Sbjct: 683 MNQIVSWATLASSLVAP-LLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMF 741

Query: 735 LFVRFEFGHLSD--------VELLQLKVDSTKISTGEYV--ELRRTVVCVSFVLCPLFGT 784
           ++++ E   L          +  +Q   D+      +    ++RR    V F+L   FGT
Sbjct: 742 VWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLVFFLLTAFFGT 801

Query: 785 GNFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQESIQRLC 844
           GN ASINSF+ +++  F++VFSPF M  L++ K+LIP +LV  AF ++    Q S + L 
Sbjct: 802 GNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQITTQLSSKGLF 861

Query: 845 CFSLIFTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSMCISLALLLLLSISSHLMAFEFR 904
              LI +D M++ FF  ++D GSWLDIG SIS +++ M +++ L+ L  ++  L   + +
Sbjct: 862 LVVLIISDIMALHFFFLVKDSGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLTTKKLQ 921

Query: 905 KFPGKRNH 912
                ++H
Sbjct: 922 LCGKPKSH 929
>ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class N; endoplasmic
           reticulum membrane protein [Homo sapiens]
 gb|AAD11432.1| (AF109219) Mcd4p homolog [Homo sapiens]
          Length = 931

 Score =  990 bits (2533), Expect = 0.0
 Identities = 321/967 (33%), Positives = 495/967 (50%), Gaps = 100/967 (10%)

Query: 5   FLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDTFNK- 63
           F    + +H V   SIFD+Y+TSPLVHG+ PQF      PA+R+ +  ADGLR D   + 
Sbjct: 4   FFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFT-PLPPPARRLVLFVADGLRADALYEL 62

Query: 64  ---YPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPV 120
                 ++P++ +I+   +G +G+S + +PTESRPGHVA+ AG  ED+SAVAKGWK+NPV
Sbjct: 63  DENGNSRAPFIRNII-MHEGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121

Query: 121 QFDSVFNRSSYSWMWGSPDIVNLFDDLPNAE---SFSYSADEEDFASKDASNLDKWVFEH 177
           +FDS+FN S Y+W WGSPDI+ +F    + +   ++SY A  EDF ++DA+ LD WVF++
Sbjct: 122 EFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDFGAQDATKLDTWVFDN 181

Query: 178 FENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKV 237
            ++F   A+ +++L  K+ E+K +FFLHLLGIDTNGH ++P SR Y  NIK VD G++++
Sbjct: 182 VKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDDGVKEI 241

Query: 238 QHLVDAFF-GDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQG-------- 288
             + + F+  D KT ++FTSDHGMTDWGSHGAG   E LTP V WGAG+K          
Sbjct: 242 VSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSAQQF 301

Query: 289 ------------GPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAI 336
                         +LD+NQ D+APL+++LIG P P+NS+GILPV  +N+    ++ +++
Sbjct: 302 DDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILPVDYLNNT-DLFKAESM 360

Query: 337 EANFKQLKEQII---FLKNAKSRRLWFRQFEKFGDKAMESLRTTLAQLGRDRRFSVATSL 393
             N  Q+ EQ       K   +    F  F+   D    ++        + R+F    SL
Sbjct: 361 FTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILRKARSYIKHRKFDEVVSL 420

Query: 394 FADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIAL----VVSFLHNSTSKENLSLLVP 449
             +  HL  + + +YH YDR  LG  V   FV WI+     ++    N     +  +  P
Sbjct: 421 CKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLIIKSHSNLIKGVSKEVKKP 480

Query: 450 HHLFIIPLACSLL----FTAYCSLSMTQTIYIILPIYLISILENHSKLTQRIREHVKALS 505
            HL         +    F    +   T  +Y +LP+ +   +    ++ Q +        
Sbjct: 481 SHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWYAVLREFQVIQDL-------- 532

Query: 506 AQPDWLNKVLSVEVFVKPFLGFVG----FSITICIFVLTFMDRAFLAAVFVLLMALP--- 558
                      V V   P   FVG    F++ I + VL+F  R  L A      A P   
Sbjct: 533 ----------VVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAFAAWPFLT 582

Query: 559 QFYSHPIVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFLCHRLSRRSCL 618
           + ++   ++  S +W    L+L +FP +P VG    I L + +  +   L       S +
Sbjct: 583 RLWTRAKMT--SLSWTFFSLLLAVFPLMPVVGRKPDISLVMGA-GLLVLLLSLCVVTSLM 639

Query: 619 TRIQRMLE---LMIYVQSATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSLQPPSI 675
            R    ++   L+  +Q  +  +   V Y                +S+    Q L  P +
Sbjct: 640 KRKDSFIKEELLVHLLQVLSTVLSMYVVYS--------------TQSSLLRKQGL--PLM 683

Query: 676 ARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFLVLLTL 735
            + ISW ++  S++ P LL+ P L  RL +  L     Y LLS  YE+LF L+   L+ +
Sbjct: 684 NQIISWATLASSLVVP-LLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFV 742

Query: 736 FVRFEFGHLSDVE----------LLQLKVDSTKISTGEYVELRRTVVCVSFVLCPLFGTG 785
           ++  E   L                    D T+       ++RR    V F++   FGTG
Sbjct: 743 WINIEQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTG 802

Query: 786 NFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQESIQRLCC 845
           N ASINSF+ +++  F++VFSPF M  L++ K+LIP +LV  AF ++    Q S + L  
Sbjct: 803 NIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFL 862

Query: 846 FSLIFTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSMCISLALLLLLSISSHLMAFEFRK 905
             L+ +D M++ FF  ++D GSWLDIG SIS +++ M +++ L+ L  ++  L   + R 
Sbjct: 863 IVLVISDIMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLTTKKLRL 922

Query: 906 FPGKRNH 912
               ++H
Sbjct: 923 CGKPKSH 929
>pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragment)
 emb|CAB70839.1| (AL137607) hypothetical protein [Homo sapiens]
          Length = 825

 Score =  860 bits (2199), Expect = 0.0
 Identities = 277/862 (32%), Positives = 430/862 (49%), Gaps = 94/862 (10%)

Query: 106 EDISAVAKGWKKNPVQFDSVFNRSSYSWMWGSPDIVNLFDDLPNAE---SFSYSADEEDF 162
           ED+SAVAKGWK+NPV+FDS+FN S Y+W WGSPDI+ +F    + +   ++SY A  EDF
Sbjct: 1   EDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDF 60

Query: 163 ASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQ 222
            ++DA+ LD WVF++ ++F   A+ +++L  K+ E+K +FFLHLLGIDTNGH ++P SR 
Sbjct: 61  GAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRD 120

Query: 223 YIDNIKVVDSGIEKVQHLVDAFF-GDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAW 281
           Y  NIK VD G++++  + + F+  D KT ++FTSDHGMTDWGSHGAG   E LTP V W
Sbjct: 121 YKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTW 180

Query: 282 GAGVKQG--------------------GPKLDLNQIDLAPLISALIGCPIPVNSMGILPV 321
           GAG+K                        +LD+NQ D+APL+++LIG P P+NS+GILPV
Sbjct: 181 GAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILPV 240

Query: 322 QMMNSKGSSYEFKAIEANFKQLKEQII---FLKNAKSRRLWFRQFEKFGDKAMESLRTTL 378
             +N+    ++ +++  N  Q+ EQ       K   +    F  F+   D    ++    
Sbjct: 241 DYLNNT-DLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILRKA 299

Query: 379 AQLGRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIAL----VVSF 434
               + R+F    SL  +  HL  + + +YH YDR  LG  V   FV WI+     ++  
Sbjct: 300 RSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLIIKS 359

Query: 435 LHNSTSKENLSLLVPHHLFIIPLACSLL----FTAYCSLSMTQTIYIILPIYLISILENH 490
             N     +  +  P HL         +    F    +   T  +Y +LP+ +   +   
Sbjct: 360 HSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWYAVLRE 419

Query: 491 SKLTQRIREHVKALSAQPDWLNKVLSVEVFVKPFLGFVG----FSITICIFVLTFMDRAF 546
            ++ Q +                   V V   P   FVG    F++ I + VL+F  R  
Sbjct: 420 FQVIQDL------------------VVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYRYM 461

Query: 547 LAAVFVLLMALP---QFYSHPIVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCILSPI 603
           L A      A P   + ++   ++  S +W    L+L +FP +P VG    I L + +  
Sbjct: 462 LTAGLTAFAAWPFLTRLWTRAKMT--SLSWTFFSLLLAVFPLMPVVGRKPDISLVMGA-G 518

Query: 604 ITAFLCHRLSRRSCLTRIQRMLE---LMIYVQSATAFMIAVVNYGFEKVKKLIQNNWKKK 660
           +   L       S + R    ++   L+  +Q  +  +   V Y                
Sbjct: 519 LLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYS--------------T 564

Query: 661 KSNSKSSQSLQPPSIARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSIS 720
           +S+    Q L  P + + ISW ++  S++ P LL+ P L  RL +  L     Y LLS  
Sbjct: 565 QSSLLRKQGL--PLMNQIISWATLASSLVVP-LLSSPVLFQRLFSILLSLMSTYLLLSTG 621

Query: 721 YESLFMLIFLVLLTLFVRFEFGHLSDVE----------LLQLKVDSTKISTGEYVELRRT 770
           YE+LF L+   L+ +++  E   L                    D T+       ++RR 
Sbjct: 622 YEALFPLVLSCLMFVWINIEQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRA 681

Query: 771 VVCVSFVLCPLFGTGNFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFA 830
              V F++   FGTGN ASINSF+ +++  F++VFSPF M  L++ K+LIP +LV  AF 
Sbjct: 682 FFLVFFLVTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFE 741

Query: 831 SIVRFDQESIQRLCCFSLIFTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSMCISLALLL 890
           ++    Q S + L    L+ +D M++ FF  ++D GSWLDIG SIS +++ M +++ L+ 
Sbjct: 742 AVQLTTQLSSKSLFLIVLVISDIMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVF 801

Query: 891 LLSISSHLMAFEFRKFPGKRNH 912
           L  ++  L   + R     ++H
Sbjct: 802 LNGLAQLLTTKKLRLCGKPKSH 823
>pir||T40715 hypothetical protein SPBC839.08c - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA17011.1| (AL021816) hypothetical protein [Schizosaccharomyces pombe]
 emb|CAB46701.1| (AL096796) hypothetical protein [Schizosaccharomyces pombe]
          Length = 935

 Score =  833 bits (2130), Expect = 0.0
 Identities = 271/957 (28%), Positives = 468/957 (48%), Gaps = 92/957 (9%)

Query: 1   MSWKFLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDT 60
           M  + L+  I  H+V + SIFD+Y+ +PL+HG+  +  ++ EAPAKR+F+I  DGLR D 
Sbjct: 1   MFGRLLLLGILFHVVFLKSIFDIYFVTPLIHGM--KQYSAGEAPAKRLFLIVGDGLRPDK 58

Query: 61  FN-KYPDK---------SPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISA 110
               + +K         +P+L SI+ +  G +G+S + +PTESRPGHVA+ AG  ED+SA
Sbjct: 59  LLQPHSEKVIGEEQTYAAPFLRSII-QNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSA 117

Query: 111 VAKGWKKNPVQFDSVFNRSSYSWMWGSPDIVNLFDDLPN----AESFSYSADEEDFASKD 166
           V KGWKKNPV FDSVFN+S +++ +GS DI+ +F +  +     ++F YS++ EDF S +
Sbjct: 118 VTKGWKKNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDF-SSN 176

Query: 167 ASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDN 226
              LD+WVF+  +  L  +  D+ L D +   K +FFLHLLGIDT GH   P S +Y++N
Sbjct: 177 GIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVEN 236

Query: 227 IKVVDSGIEKVQHLVDAFF-GDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGV 285
           I+ +D  I+++   ++ ++  D  ++W+FT+DHGM+D+GSHG G+ D   TP +AWGAG+
Sbjct: 237 IQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGI 296

Query: 286 KQGG-------------------PKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNS 326
           +                       ++D+ Q D+A L+S L+G   PVNS+G +P+  ++ 
Sbjct: 297 QSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDC 356

Query: 327 KGSSYEFKAIEANFKQLKEQIIFLKNAKSR-RLWFRQFEKFGD--KAMESLRTTLAQLGR 383
                + +    N  ++ EQ      +K +  ++FR +    +  +   S   ++     
Sbjct: 357 SSRR-KAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASFYNSVIADIE 415

Query: 384 DRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIALVVSFLHNSTSKEN 443
              + +A       +  +   + +  RYD  +L + V   +++WI  V+ F+ +   + +
Sbjct: 416 SGEYEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNIEPS 475

Query: 444 LSLLVPHHL-----FIIPLACSLLFTAYCSLSMTQTIYIILPIYLISILENHSKLTQRIR 498
             ++ P  +     F IP     +F    S       Y + P   + ++ +    T+   
Sbjct: 476 SKIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGF 535

Query: 499 EHVKALSAQPDWLN--KVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAVFVLLMA 556
           ++   ++ Q    +  K+L + + +   L F+         V ++  R   + + + L A
Sbjct: 536 KNFLTVAKQKHGFSLLKILFISLCILCLLQFI---------VYSYFHREGFSVILMGLAA 586

Query: 557 LPQF------YSHPIVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFLCH 610
            P        +SH  +S    +W  L  +LC F  LP     +     +L      F   
Sbjct: 587 WPWLLHADYAFSHKTISV---SWSVLTSLLCFFTILPVNKKES-----LLFIFAGGFAMS 638

Query: 611 RLSRRSCLTRIQRMLELMIYVQSATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSL 670
                  L R  +  +    V +    +  ++      V   I ++ +         +++
Sbjct: 639 VAGVFYILYRRNQAFQYSSTVTNKQLVLQVLIIMATVPVTLKIADSLQ---------RNI 689

Query: 671 QPPSIARWISWTSIPLSVIAPS---LLTGPYLVDRLIAYALCFYVPYSLLSISYESLFML 727
             P I R +++     S I PS        Y +DRL    L F     +LSIS+E+LF +
Sbjct: 690 AIPPILRLVAFGLFITSYIIPSHHIRSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYV 749

Query: 728 IFLVLLTLFVRFEFGHLSDVELLQLKVDSTKISTGE--YVELRRTVVCVSFVLCPLFGTG 785
           +  + L L++  E       E L  +    K +        +R ++    F+    FGTG
Sbjct: 750 VLFITLGLWMELETELQKYTEQLHPEYSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTG 809

Query: 786 NFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQESIQRLCC 845
           N AS+++F   ++  FI VF+P T   LL+  +L+P + +++AF  I+      IQ++  
Sbjct: 810 NVASLSTFALDSVKRFIPVFNPVTQGALLMYTILVPFIALSAAFG-IMNKRLGGIQQVTF 868

Query: 846 FSLI-FTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSMCISLALLLLLSISSHLMAF 901
           F  +   D +++ FF+ ++DEGSW DIG+SIS F    CIS  L+L ++   H  A 
Sbjct: 869 FLAVGMADIVTINFFYLVKDEGSWKDIGVSISHF----CISNFLILFITALEHASAI 921
>gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melanogaster]
          Length = 874

 Score =  827 bits (2114), Expect = 0.0
 Identities = 252/939 (26%), Positives = 431/939 (45%), Gaps = 98/939 (10%)

Query: 6   LIASITVHLVLIYSIFDVYYTSPLVHGIPPQF---INSQEAPAKRIFIISADGLRYDTFN 62
           +  ++ VH++L+ SIF +Y+ SP++ G+ PQ        E PA R+ +I  DG R D+F 
Sbjct: 3   IAYALVVHVLLLGSIFVIYFRSPVITGLTPQKHLLYYGLEPPANRLVLIVTDGFRADSFF 62

Query: 63  KYPDK-SPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPVQ 121
           +   +  P L  I   R+G+ G+SR+ +PTE+RPGH+ + AG+ ED SAV +GWK NP+ 
Sbjct: 63  EENCRYVPNLRKIF-LREGVVGVSRTRVPTETRPGHITLIAGLYEDPSAVLRGWKSNPID 121

Query: 122 FDSVFNRSSYSWMWGSPDIVNLFDDLPNAES---FSYSADEEDFASKDASNLDKWVFEHF 178
           FD+VFNRSS ++ WG+ D++N+F  + N        Y+ D +     DA   D+WVF+  
Sbjct: 122 FDTVFNRSSQTYAWGANDVLNVFSHVSNGGEINLRFYNHDLDFSPGYDAYEEDEWVFKRV 181

Query: 179 ENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQ 238
           +  L+  +         R Q  +FFLHLLG+DT GH +KP + ++   ++  + G+  + 
Sbjct: 182 KLLLQQKREA-----LQRAQNVVFFLHLLGLDTAGHVHKPGAPKFRRTLEKTEKGVYAIY 236

Query: 239 HLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGGPKLDLNQID 298
              +  F D +TA+L T+DHGMTD G+  A       T F+    G     P  +L Q  
Sbjct: 237 QEFERVFPDKRTAYLLTADHGMTDSGASRAVPKPGGRT-FMPNNEGPAM--PLHELEQAQ 293

Query: 299 LAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEANFKQLKEQIIFLKNAKSRRL 358
           L PL+SAL+G   P+N+ G LP+  +N     YE  A   N  QL EQ + L+    +  
Sbjct: 294 LTPLMSALLGLAPPMNNFGKLPLGYLNV-SKEYEAMAAHVNALQLLEQYVALQKQHKKGF 352

Query: 359 W---FRQFEKFGDKAMESLRTTLAQLGRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQM 415
           +     +++    +A++  + T+ QL + R +S+             E I +YH Y R++
Sbjct: 353 FADILLEYDVLNAEAIKRYKDTIVQLQKKREYSLCIDKSQVIMSQALEGIDYYHGYYRRV 412

Query: 416 LGAAVSCSFVAWIALVVSFLHNS-TSKENLSLLVPHHLFIIPLACSLLFTAYCSL----S 470
           L  + + +F+ W+  +   L  +  SK  L L   + +  + +  S++    C L     
Sbjct: 413 LLLSTTSTFLGWMFYIYRLLSRNRASKVELVLERSNKIVRVSIVSSVIVLIICLLSQGTP 472

Query: 471 MTQTIYIILPIYLISILENHSKLTQRIREHVKALSAQPDWLNKVLSVEVFVKPFLGFVGF 530
           +  + Y++LP ++                 +KAL       +       +  P L    +
Sbjct: 473 LDISFYLLLPYFVW----------------LKALQPWNINFSS-SPASAYSVPALQTSMW 515

Query: 531 SITI-----CIFVLTFMDRAFLAAVFVLLMALPQFYSHPIVSYWSKTWLTLCLVLCIFPF 585
            + +      + V TF +R  +A  F +      + +    S    +WL L L+L  FP 
Sbjct: 516 QLVLLIACAELMVFTFFERRLIALCFCVFACYNSWENFQWKSRDFFSWLALVLILSCFPL 575

Query: 586 LPA-VGVSTHIPLCILSPIITAFLCHRLSRRSCLTRIQRMLELMIYVQSATAFMIAVVNY 644
           LP  VG      L     +I          R C     +    +I +Q     + A ++ 
Sbjct: 576 LPLSVGYQNGYLLGAGVIVIFTNSFWNSKSRLCYRNHTKYSNALILLQ---TILCAYLH- 631

Query: 645 GFEKVKKLIQNNWKKKKSNSKSSQSLQPPSIARWISWTSIPLSVIAPSLLTGPYLVDRLI 704
                                 S  +  P   +  SW  +  +  +  L     L  RL 
Sbjct: 632 ----------------------SNGINIPIPLKLASWLYLVYAFASILLSKESRLDLRLA 669

Query: 705 AYALCFYVPYSLLSISYESLFMLIFLVLLTLFVRFEFGHLSDVELLQLKVDSTKISTGEY 764
                    Y+ L  SYE++F+ +  + L + +R                   + +  E 
Sbjct: 670 QIGFNLGSLYATLCTSYEAVFVQLLTIELNISLR------------------AQSARAER 711

Query: 765 VELRRTVVCVSFVLCPLFGTGNFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILL 824
             LR     + +    LFG+GN ASI+SF+P+    ++S F+PF +  L++LKLL+P++L
Sbjct: 712 SVLRLAFTLLLYTFFSLFGSGNIASISSFDPNIARCYLSHFAPFVIMGLVLLKLLVPVVL 771

Query: 825 VTSAFASIVRFDQESIQRLCCFSLIFTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSMCI 884
           + S   +   F ++  +++    L+  D M + F   +R++GSWLDIG SIS F++    
Sbjct: 772 IMSVIYANSEFVRQHEEQIFICLLLICDVMGLNFLFLVRNQGSWLDIGTSISHFVIMEVT 831

Query: 885 SLALLLLLSISSHLM------AFEFRKFPGKRNHQEIES 917
           +L +L++   +  L+        +F+  P +  H ++ S
Sbjct: 832 TLVMLVIFYTAKQLLRVIPWEEIDFKMLPLRLIHWDVIS 870
>gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melanogaster]
          Length = 919

 Score =  814 bits (2081), Expect = 0.0
 Identities = 220/953 (23%), Positives = 375/953 (39%), Gaps = 104/953 (10%)

Query: 7   IASITVHLVLIYSIFDVYYTSPLVHGIPPQFI---NSQEAPAKRIFIISADGLRYDT-FN 62
           I ++ VHL+L+ SI  +Y+ S ++  + P         E PA R+ +   DGLR  +   
Sbjct: 4   IQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSVLA 63

Query: 63  KYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPVQF 122
            +    P L  +  E + + G+SR+  PT +RPGH+AIF G  ED +A       NP  F
Sbjct: 64  DHCSAVPDLRELFVE-QALVGISRACPPTVTRPGHIAIFGGFNEDPAATLT---WNPSTF 119

Query: 123 DSVFNRSSYSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASNLDKWVFEHFENFL 182
           DSVFNRS  +  W   ++  +F  LP   +             D   LD+W F+   NF+
Sbjct: 120 DSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFARSDISDRLRLDQWTFDKVRNFM 179

Query: 183 ETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVD 242
              +  + L D       IFF++L  ID   H + P S  + + +     GI +   L +
Sbjct: 180 TNEQNVQPLRD---ATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFE 236

Query: 243 AFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQ--------------- 287
           + F D +TA+L T+D+G++    HG G +  V TPF+ WGAGVK+               
Sbjct: 237 SVFNDSRTAYLMTADYGISL---HGGGGERGVETPFILWGAGVKRSAPNPGQNFTAGENG 293

Query: 288 -GGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEANFKQLKEQ 346
              P   L QI LAPL+SALIG P P+N+M ++P+  +N     YE + +  N  QL  Q
Sbjct: 294 PILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLN-TSVQYELQVLHLNAMQLLAQ 352

Query: 347 IIFLKNAKSRRLWF---RQFEKFGDKAMESLRTTLAQLGRDRRFSVATSLFADNAHLMKE 403
              L       + +    +FE  G   +E+    +  L    ++  A  +    A L +E
Sbjct: 353 ARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEALKVSHKIAKLAQE 412

Query: 404 AIVFYHRYDRQMLGAAVSCSFVAWIALVVSFLHNSTSKENLSLLVPHHLFIIPLACSLLF 463
            + +YH Y    L  A + S++ W  L++  L   ++                L  + L 
Sbjct: 413 CMEYYHGYYHLPLLVATTASYLVWFYLLLVRLARESNHPKSE-------RKGYLTWTTLM 465

Query: 464 -----------TAYCSLSMTQTIYIILPIYLISILENHSKLTQRIREHVKALSAQPDWLN 512
                           +      Y++LP  ++ +                    Q   L 
Sbjct: 466 MCLGGLVLLELMILQRVPHLTAFYLLLPFGILILALAERP-------------CQDRDL- 511

Query: 513 KVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAVFVLLMALPQFYSHPIVSYWSKT 572
                 +   P L  VG  +   + +L     + +  +++ ++ L    +    S     
Sbjct: 512 ------MCQFPVLHLVGIVMPGVLLILMAFHNSHIGLLYLPIVCLNNRRAFFRPSLKLIF 565

Query: 573 WLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFLCHRLSRRSCLTRIQRMLELMIYVQ 632
           WL L  +L        V  S  +     +  +     H +     L+ I+    L++  Q
Sbjct: 566 WLALVFLLSGILL---VKQSASLHFITDTIGVYIGNSHVVYFSMILSIIR---PLILGHQ 619

Query: 633 SATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSLQPPSIARWISWTSIPLSVIAPS 692
            +T   I  VN     V       W        + Q +     A   S+      +  P 
Sbjct: 620 HSTRVWI--VNMAALLVTAYGIYQWD-------ADQPVCTYVYAACWSYLLFAF-LSIPY 669

Query: 693 LLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFLVLLTLFVRFEFGHLSDVELLQ- 751
             T   L  RL          + +L+ S  SLF+ I +    L +       S   L   
Sbjct: 670 SGTKD-LRRRLELIIFNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESFSYANLKDA 728

Query: 752 ----------LKVDSTKISTGEYVEL----RRTVVCVSFVLCPLFGTGNFASINSFNPST 797
                     L+    +        +    R   + + ++    FGTG++    +F P T
Sbjct: 729 IANQQQNNQGLEESRNESPNNPLEHVRQSYRYAALILLYLYISFFGTGHWFFNFTFKPMT 788

Query: 798 LNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQESIQRLCCFSLIFTDFMSMC 857
             LF   F    +   ++LK+ IP ++V S+  ++V F +++++ +     +  D MS+ 
Sbjct: 789 SRLFFPQFHLHMLVAFILLKIFIPSIIVMSSIYALVSFGRKNVRSIFICLFLMNDAMSLY 848

Query: 858 FFHQLRDEGSWLDIGMSISQFIVSMCISLALLLLLSISSHLMAFEFRKFPGKR 910
           F + + + GS   +  S+ + +VS    + LL+   I+   +A   +  P  R
Sbjct: 849 FCYFVINRGSLEKVRESLDRLLVSHVFIILLLVCSWIAKGFLANTKKDKPTPR 901
>dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N short form [Mus
           musculus]
          Length = 798

 Score =  799 bits (2042), Expect = 0.0
 Identities = 267/831 (32%), Positives = 416/831 (49%), Gaps = 102/831 (12%)

Query: 5   FLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDTFNK- 63
           F    + +H V   SIFD+Y+TSPLVHG+ PQF      PAKR+ +  ADGLR DT  + 
Sbjct: 4   FFALGLLIHFVFFVSIFDIYFTSPLVHGMTPQFT-PLPPPAKRLVLFVADGLRADTLYEL 62

Query: 64  ---YPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPV 120
                 ++P++ +++   +G +G+S + +PTESRPGHVA+ AG  ED+SAVAKGWK+NPV
Sbjct: 63  DEDGNSRAPFIRNVI-MHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121

Query: 121 QFDSVFNRSSYSWMWGSPDIVNLFDDLPNAE---SFSYSADEEDFASKDASNLDKWVFEH 177
           +FDS+FN S Y+W WGSPDI+ +F    + +   ++SY A  EDF + DA+ LD WVF+ 
Sbjct: 122 EFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWVFDK 181

Query: 178 FENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKV 237
            ++F + A+ +++L  K+ E+K +FFLHLLG+DTNGH ++P SR+Y DNIK VD G++++
Sbjct: 182 VKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIKKVDDGVKEI 241

Query: 238 QHLVDAFFGDH-KTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQG-------- 288
             +   F+GD  KTA++FTSDHGMTDWGSHGAG   E LTPFV WGAG+K          
Sbjct: 242 VSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQY 301

Query: 289 ------------GPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAI 336
                         + D+NQ D+APL+++LIG P P+NS+GILPV  +N+ G  ++ +++
Sbjct: 302 DDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGL-FKAESM 360

Query: 337 EANFKQLKEQII---FLKNAKSRRLWFRQFEKFGDKAMESLRTTLAQLGRDRRFSVATSL 393
             N  Q+ EQ       K   +    F  F+   D     +        +  +F    SL
Sbjct: 361 FTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFDEVVSL 420

Query: 394 FADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIAL----VVSFLHNSTSKENLSLLVP 449
             +   L    + +YH YDR  LG  V+  FV W++     ++    N           P
Sbjct: 421 CEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSNIPKGTRKEGKKP 480

Query: 450 HHLFIIPLACSLL----FTAYCSLSMTQTIYIILPIYLISILENHSKLTQRIREHVKALS 505
           H L +     + +    F    +   T  +Y +LP+ +   +    ++ Q +   V++L 
Sbjct: 481 HCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVIQDL---VESLL 537

Query: 506 AQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAVFVLLMALP---QFYS 562
             P           FV   L    F++ I + VL+F  R  L A  ++    P   Q ++
Sbjct: 538 TFPR--------SHFVAYLL---VFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWT 586

Query: 563 HPIVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFLCHRLSRRSCLTRIQ 622
              ++    +W    L+L +FP +P VG   ++ L + +     FL   LS     T  +
Sbjct: 587 RAKIT--FLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGA----GFLVLLLSLAVVTTLGK 640

Query: 623 RMLELM--------IYVQSATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSLQPPS 674
           R ++L+        + + S    M  V +     +KK                     P 
Sbjct: 641 RNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGL------------------PL 682

Query: 675 IARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFLVLLT 734
           + + +SW ++  S++AP LL+   L  RL +  L     Y LLS  YE+LF L+   L+ 
Sbjct: 683 MNQIVSWATLASSLVAP-LLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMF 741

Query: 735 LFVRFEFGHLSD--------VELLQLKVDSTKISTGEYV--ELRRTVVCVS 775
           ++++ E   L          +  +Q   D+      +    ++RR      
Sbjct: 742 VWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLFF 792
>gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinositol glycan, class N [Mus
           musculus]
          Length = 826

 Score =  793 bits (2028), Expect = 0.0
 Identities = 268/837 (32%), Positives = 418/837 (49%), Gaps = 102/837 (12%)

Query: 5   FLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDTFNK- 63
           F    + +H V   SIFD+Y+TSPLVHG+ PQF      PAKR+ +  ADGLR DT  + 
Sbjct: 4   FFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFT-PLPPPAKRLVLFVADGLRADTLYEL 62

Query: 64  ---YPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPV 120
                 ++P++ +++   +G +G+S + +PTESRPGHVA+ AG  ED+SAVAKGWK+NPV
Sbjct: 63  DEDGNSRAPFIRNVII-HEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121

Query: 121 QFDSVFNRSSYSWMWGSPDIVNLFDDLPNAE---SFSYSADEEDFASKDASNLDKWVFEH 177
           +FDS+FN S Y+W WGSPDI+ +F    + +   ++SY A  EDF + DA+ LD WVF+ 
Sbjct: 122 EFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWVFDK 181

Query: 178 FENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKV 237
            ++F + A+ +++L  K+ E+K +FFLHLLGIDTNGH ++P SR+Y DNIK VD G++++
Sbjct: 182 VKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEI 241

Query: 238 QHLVDAFFGDH-KTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQG-------- 288
             +   F+GD  KTA++FTSDHGMTDWGSHGAG   E LTPFV WGAG+K          
Sbjct: 242 VSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQY 301

Query: 289 ------------GPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAI 336
                         + D+NQ D+APL+++LIG P P+NS+GILPV  +N+ G  ++ +++
Sbjct: 302 DDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGL-FKAESM 360

Query: 337 EANFKQLKEQII---FLKNAKSRRLWFRQFEKFGDKAMESLRTTLAQLGRDRRFSVATSL 393
             N  Q+ EQ       K   +    F  F+   D     +        +  +F    SL
Sbjct: 361 FTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFDEVVSL 420

Query: 394 FADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIAL----VVSFLHNSTSKENLSLLVP 449
             +   L    + +YH YDR  LG  V+  FV W++     ++    N           P
Sbjct: 421 CEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSNIPKGTRKEGKKP 480

Query: 450 HHLFIIPLACSLL----FTAYCSLSMTQTIYIILPIYLISILENHSKLTQRIREHVKALS 505
           H L +     + +    F    +   T  +Y +LP+ +   +    ++ Q +   V++L 
Sbjct: 481 HCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVIQDL---VESLL 537

Query: 506 AQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAVFVLLMALP---QFYS 562
             P           FV   L    F++ I + VL+F  R  L A  ++    P   Q ++
Sbjct: 538 TFPR--------SHFVAYLL---VFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWT 586

Query: 563 HPIVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFLCHRLSRRSCLTRIQ 622
              ++    +W    L+L +FP +P VG   ++ L + +     FL   LS     T  +
Sbjct: 587 RAKIT--FLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGA----GFLVLLLSLAVVTTLGK 640

Query: 623 RMLELM--------IYVQSATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSLQPPS 674
           R ++L+        + + S    M  V +     +KK                     P 
Sbjct: 641 RNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGL------------------PL 682

Query: 675 IARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFLVLLT 734
           + + +SW ++  S++AP LL+   L  RL +  L     Y LLS  YE+LF L+   L+ 
Sbjct: 683 MNQIVSWATLASSLVAP-LLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMF 741

Query: 735 LFVRFEFGHLSD--------VELLQLKVDSTKISTGEYV--ELRRTVVCVSFVLCPL 781
           ++++ E   L          +  +Q   D+      +    ++RR    +  +    
Sbjct: 742 VWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLILLIFPVF 798
>ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; Mcd4p [Saccharomyces
           cerevisiae]
 sp|P36051|YKQ5_YEAST HYPOTHETICAL 105.7 KD PROTEIN IN TPK3-PIR1 INTERGENIC REGION
 pir||S37786 hypothetical protein YKL165c - yeast (Saccharomyces cerevisiae)
 emb|CAA81489.1| (Z26877) unknown [Saccharomyces cerevisiae]
 emb|CAA82007.1| (Z28165) ORF YKL165c [Saccharomyces cerevisiae]
 prf||2118404A ORF [Saccharomyces cerevisiae]
          Length = 919

 Score =  786 bits (2010), Expect = 0.0
 Identities = 280/953 (29%), Positives = 470/953 (48%), Gaps = 110/953 (11%)

Query: 5   FLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDTFNKY 64
            L   +  HL  ++SIFD+Y+ SPLVHG+ P + ++   PAKR+F+I  DGLR DT    
Sbjct: 9   LLAVGVLFHLFYLWSIFDIYFISPLVHGMSP-YQSTPTPPAKRLFLIVGDGLRADTTFDK 67

Query: 65  PDK---------SPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGW 115
                       +P++ S++      YG+S + +PTESRPGHVA+ AG  ED+SAV KGW
Sbjct: 68  VTHPVSGKTEFLAPFIRSLV-MNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGW 126

Query: 116 KKNPVQFDSVFNRSSYSWMWGSPDIVNLFDDLPN----AESFSYSADEEDFASKDASNLD 171
           K NPV FDS FN+S++++ +GSPDI+ +F D  +     +++ Y    EDF ++ +  LD
Sbjct: 127 KSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDF-TQSSIELD 185

Query: 172 KWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVD 231
            +VF H +     +  +  L+ ++R+  ++FFLHLLG DT GH  +P S +Y DN+K +D
Sbjct: 186 AFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYID 245

Query: 232 SGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQG--- 288
             I  +   V+ FF D KTA++FT+DHGM+ +GSHG G  +   TP VAWGAG+ +    
Sbjct: 246 DQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHN 305

Query: 289 ----------------GPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYE 332
                             + D+ Q D+A L+S LIG   P NS+G LP+  ++ K  S +
Sbjct: 306 PFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGK-ESDK 364

Query: 333 FKAIEANFKQLKEQIIFLKNAK-SRRLWFRQFEKFGDKA----MESLRTTLAQLGRDRRF 387
             A+  N + + EQ +  ++     + +++++ KF +K+    +E + T + ++     +
Sbjct: 365 LAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISEGENY 424

Query: 388 --SVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIA-----LVVSFLHNSTS 440
               A +L  +   +  E + +   Y+ + +   V+  FV WI       + SF+  +  
Sbjct: 425 LEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFILENVI 484

Query: 441 KENLSLLVPHHLF--IIPLACSLLFTAYCSLSMTQTIYIILPIYLI-SILENHSKLTQRI 497
            +  +  + H +F  I  L   +LF  Y        +Y++ P+Y    I  N S L   I
Sbjct: 485 DDQKASPLSHAVFGSIGILLNWILF--YQHSPFNFYMYLLFPLYFWSYIFTNRSVLRSGI 542

Query: 498 REHVKALSAQPDWLNKVLSVEVFVKPFLGFVG-FSITICIFVLTFMDRAFLAAVFVLLMA 556
           +E  K  S     L  +  + V+     GF   ++ T+   +L F    F+  V  L + 
Sbjct: 543 KEFFKGTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILAFY--PFICGVRELSVN 600

Query: 557 LPQFYSHPIVSYWSKTWLTLCLVLCIFPFLPAVGVS--THIPLCILSPIITAFLCHRLSR 614
                           W+   ++L  F    AV +     I L  L  I++AF     + 
Sbjct: 601 --------------ILWIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAF----YAL 642

Query: 615 RSCLTRIQRMLELMIYVQ-SATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSLQPP 673
               +RI      +  +Q S  A M+AV +            + + ++   + SQ     
Sbjct: 643 YKIHSRINSYTRAIFAIQISLVAAMLAVTHRS--------VISLQLRQGLPRESQ----- 689

Query: 674 SIARWISW--TSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFLV 731
            +A WI +  +   + ++        Y V  LI Y L F   + +L+IS+ESLF  +F  
Sbjct: 690 -VAGWIIFFVSLFVMPILHYRKPNNDYKVRLLIIY-LTFAPSFIILTISFESLFYFLFTS 747

Query: 732 LLTLFVRFEFGHLSDVELLQLKVDSTKISTGEYVELRRTVVCVSFVLCPLFGTGNFASIN 791
            +  ++  E    + ++ ++ + D   +       LR +V+    +    FGTGN ASI+
Sbjct: 748 YMVQWIEIE----NKIKEMKTQKDENWLQV-----LRVSVIGFFLLQVAFFGTGNVASIS 798

Query: 792 SFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASI---VRFDQESIQRLCCFSL 848
           SF+  ++   + +F PF M  LL+LKL+IP  L+++    +   + F   +I  L     
Sbjct: 799 SFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIIS-- 856

Query: 849 IFTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSMCISLALLLLLSISSHLMAF 901
             +D +S+ FF+ LR EGSWLDIG++IS + +++  SL +L +L +  H++  
Sbjct: 857 -MSDILSLNFFYLLRTEGSWLDIGITISNYCLAILSSLFML-ILEVLGHVLLK 907
>gb|AAF54657.1| (AE003692) CG6790 gene product [Drosophila melanogaster]
 gb|AAL28155.1| (AY060607) GH02677p [Drosophila melanogaster]
          Length = 858

 Score =  746 bits (1907), Expect = 0.0
 Identities = 175/923 (18%), Positives = 325/923 (34%), Gaps = 124/923 (13%)

Query: 2   SWKFLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFI---NSQEAPAKRIFIISADGLRY 58
            WK  +  +   L+L+  I  ++Y S  +  + PQ           A R+ +   +GLR 
Sbjct: 3   LWKSKVVLVH--LLLLICIMRIFYQSGPLSQLEPQKTLLDMGVPPAADRLVVFLLEGLRA 60

Query: 59  DTFNKYP-DKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKK 117
           DT        + Y+  I+  R+G+ G+S++ +PT +R   VA+FAG     S +      
Sbjct: 61  DTLFSDNCSGAVYIRDII-LRQGLVGISKTSVPTLTRSAEVALFAGFNPMPSIL------ 113

Query: 118 NPVQFDSVFNRSSYSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASNLDKWVFEH 177
               FD++FNR               FD      +F                     F H
Sbjct: 114 PTSNFDTIFNR------------TLAFDK----GAFLR-------------------FSH 138

Query: 178 FENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKV 237
             +          L       K +  ++L  +     G  P+   +   +      I   
Sbjct: 139 LSDLRRRLTKRACLEKLWYANKLVMLVNLAEVG----GASPLDIGFQMKLHNTQRNIRDA 194

Query: 238 QHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQ---------- 287
             L++A F D KTA+L+TS HG+T +GSHG GSD+E   PF+ WGAGVK           
Sbjct: 195 YELIEATFNDSKTAYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGVKHVTENITSDFV 254

Query: 288 -----GGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEANFKQ 342
                G     L+QI LAPL+SALIG P PVN++ ILP   M      Y  K++  N  Q
Sbjct: 255 LNNGVGMQLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSR-EYARKSVHLNALQ 313

Query: 343 LKEQIIFLKNAKSRRLWFRQFEKFGDKAMESLRTTLAQLGRD---RRFSVATSLFADNAH 399
           L  Q   +     R ++ +   K  D  ++ +     Q+         S A         
Sbjct: 314 LLTQAKAIIRLHERGVFHKWLPKDKDLDLQQIAYYQNQMDHLLDMGWRSKALETSTLAIK 373

Query: 400 LMKEAIVFYHRYDRQMLGAAVSCSFVAWIALVVSFLHNSTSKENLSLLVPHHLFIIPLAC 459
           +  +++ FYH Y    L      + + W    +  L  +       ++ PH++    L  
Sbjct: 374 VALKSLKFYHNYYHIPLVVTTVLALLGWQFYQLVKLSQN-------VMAPHYMRRGYLTW 426

Query: 460 SLLFTAYCSLSMTQTIYIILPIYLISILENHSKLTQRIREHVKALSAQPDWLNKVLSVEV 519
             +F A   L + + +++    ++  I      +   +     A   Q            
Sbjct: 427 CTIFLASLGLLLGEMVFLQWAPFMTVICL---VVPFGVWCMTLAALPQNGGWIFE----- 478

Query: 520 FVKPFLGFVGFSITICIFVLTFMDRAFLAAVFVLLMALPQF--YSHPIVSYWSKTWLTLC 577
              P            + + +      L+  ++L +       + HP   + +   L   
Sbjct: 479 ---PLKHLRWIVGPAAVMIASIYCNCPLSLAYILCVGFYNRRGWLHPSPKFLAWLALV-- 533

Query: 578 LVLCIFPFLPAVGVSTHIPLCILSPIITAFLCHRLSRRSCLTRIQRMLELMIY--VQSAT 635
                      +          +  ++T            + +   ML +++   V +  
Sbjct: 534 ----------LLLGGFLWSQKGMQILMTTN-------YRVVLQAISMLVVIVRPCVLNEN 576

Query: 636 AFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSLQPPSIARWISWTSIPLSVIAPSLLT 695
                 V  G       I                   P      +W  +  +  +    +
Sbjct: 577 HKWKVWVINGGILFVAAI--------GIFLKEMGKPVPLYLFAANWAYLIYAFASVPCSS 628

Query: 696 GPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFLVLLTLFVRFEFGHLSDVELLQLKVD 755
                 RL          + LLS SY SLF    ++   + +          E +++   
Sbjct: 629 RTTPQSRLELIRFNLLTLHVLLSDSYVSLFAQGLIIEYQMGLEVHEKFKEADEDVKILTS 688

Query: 756 STKISTGEYVELRRTVVCVSFVLCPLFGTGNFASINSFNPSTLNLFISVFSPFTMAILLI 815
           S  +        R  V  + +    LFGTG++    ++  ++  LF+   S   + +L++
Sbjct: 689 SKHLQMCY----RFAVSILLYFYASLFGTGHWVGGFTYLANSARLFLPDSSSGLVPLLVL 744

Query: 816 LKLLIPILLVTSAFASIVRFDQESIQRLCCFSLIFTDFMSMCFFHQLRDEGSWLDIGMSI 875
           + LLIP +++ ++  ++  F ++ I+ +    ++  + + + F   +     W     S+
Sbjct: 745 IHLLIPSIVIMASVVALSSFGRQQIRTIFSSLMLICNAVVLFFVVFVPHNAYWPMAHPSV 804

Query: 876 SQFIVSMCISLALLLLLSISSHL 898
              +++    + +L   SI +  
Sbjct: 805 VHALLAQLTVILILACESIVTIF 827
>ref|XP_082200.1| (XM_082200) CG6790 [Drosophila melanogaster]
          Length = 656

 Score =  575 bits (1467), Expect = e-162
 Identities = 118/678 (17%), Positives = 228/678 (33%), Gaps = 80/678 (11%)

Query: 243 AFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQ--------------- 287
             F    T  L          GSHG GSD+E   PF+ WGAGVK                
Sbjct: 6   HTFIHQHTVLLI--------SGSHGGGSDEEREAPFLLWGAGVKHVTENITSDFVLNNGV 57

Query: 288 GGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEANFKQLKEQI 347
           G     L+QI LAPL+SALIG P PVN++ ILP   M      Y  K++  N  QL  Q 
Sbjct: 58  GMQLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSR-EYARKSVHLNALQLLTQA 116

Query: 348 IFLKNAKSRRLWFRQFEKFGDKAMESLRTTLAQLGRD---RRFSVATSLFADNAHLMKEA 404
             +     R ++ +   K  D  ++ +     Q+         S A         +  ++
Sbjct: 117 KAIIRLHERGVFHKWLPKDKDLDLQQIAYYQNQMDHLLDMGWRSKALETSTLAIKVALKS 176

Query: 405 IVFYHRYDRQMLGAAVSCSFVAWIALVVSFLHNSTSKENLSLLVPHHLFIIPLACSLLFT 464
           + FYH Y    L      + + W    +  L  +       ++ PH++    L    +F 
Sbjct: 177 LKFYHNYYHIPLVVTTVLALLGWQFYQLVKLSQN-------VMAPHYMRRGYLTWCTIFL 229

Query: 465 AYCSLSMTQTIYIILPIYLISILENHSKLTQRIREHVKALSAQPDWLNKVLSVEVFVKPF 524
           A   L + + +++    ++  I      +   +     A   Q               P 
Sbjct: 230 ASLGLLLGEMVFLQWAPFMTVICL---VVPFGVWCMTLAALPQNGGWIFE--------PL 278

Query: 525 LGFVGFSITICIFVLTFMDRAFLAAVFVLLMALPQF--YSHPIVSYWSKTWLTLCLVLCI 582
                      + + +      L+  ++L +       + HP   + +   L        
Sbjct: 279 KHLRWIVGPAAVMIASIYCNCPLSLAYILCVGFYNRRGWLHPSPKFLAWLALV------- 331

Query: 583 FPFLPAVGVSTHIPLCILSPIITAFLCHRLSRRSCLTRIQRMLELMIY--VQSATAFMIA 640
                 +          +  ++T            + +   ML +++   V +       
Sbjct: 332 -----LLLGGFLWSQKGMQILMTTN-------YRVVLQAISMLVVIVRPCVLNENHKWKV 379

Query: 641 VVNYGFEKVKKLIQNNWKKKKSNSKSSQSLQPPSIARWISWTSIPLSVIAPSLLTGPYLV 700
            V  G       I                   P      +W  +  +  +    +     
Sbjct: 380 WVINGGILFVAAI--------GIFLKEMGKPVPLYLFAANWAYLIYAFASVPCSSRTTPQ 431

Query: 701 DRLIAYALCFYVPYSLLSISYESLFMLIFLVLLTLFVRFEFGHLSDVELLQLKVDSTKIS 760
            RL          + LLS SY SLF    ++   + +          E +++   S  + 
Sbjct: 432 SRLELIRFNLLTLHVLLSDSYVSLFAQGLIIEYQMGLEVHEKFKEADEDVKILTSSKHLQ 491

Query: 761 TGEYVELRRTVVCVSFVLCPLFGTGNFASINSFNPSTLNLFISVFSPFTMAILLILKLLI 820
                  R  V  + +    LFGTG++    ++  ++  LF+   S   + +L+++ LLI
Sbjct: 492 MCY----RFAVSILLYFYASLFGTGHWVGGFTYLANSARLFLPDSSSGLVPLLVLIHLLI 547

Query: 821 PILLVTSAFASIVRFDQESIQRLCCFSLIFTDFMSMCFFHQLRDEGSWLDIGMSISQFIV 880
           P +++ ++  ++  F ++ I+ +    ++  + + + F   +     W     S+   ++
Sbjct: 548 PSIVIMASVVALSSFGRQQIRTIFSSLMLICNAVVLFFVVFVPHNAYWPMAHPSVVHALL 607

Query: 881 SMCISLALLLLLSISSHL 898
           +    + +L   SI +  
Sbjct: 608 AQLTVILILACESIVTIF 625
>ref|NP_491098.1| (NM_058697) M01B12.2.p [Caenorhabditis elegans]
 pir||T33168 hypothetical protein M01B12.2 - Caenorhabditis elegans
          Length = 559

 Score =  543 bits (1385), Expect = e-153
 Identities = 559/559 (100%), Positives = 559/559 (100%)

Query: 371 MESLRTTLAQLGRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIAL 430
           MESLRTTLAQLGRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIAL
Sbjct: 1   MESLRTTLAQLGRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIAL 60

Query: 431 VVSFLHNSTSKENLSLLVPHHLFIIPLACSLLFTAYCSLSMTQTIYIILPIYLISILENH 490
           VVSFLHNSTSKENLSLLVPHHLFIIPLACSLLFTAYCSLSMTQTIYIILPIYLISILENH
Sbjct: 61  VVSFLHNSTSKENLSLLVPHHLFIIPLACSLLFTAYCSLSMTQTIYIILPIYLISILENH 120

Query: 491 SKLTQRIREHVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAV 550
           SKLTQRIREHVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAV
Sbjct: 121 SKLTQRIREHVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAV 180

Query: 551 FVLLMALPQFYSHPIVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFLCH 610
           FVLLMALPQFYSHPIVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFLCH
Sbjct: 181 FVLLMALPQFYSHPIVSYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFLCH 240

Query: 611 RLSRRSCLTRIQRMLELMIYVQSATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSL 670
           RLSRRSCLTRIQRMLELMIYVQSATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSL
Sbjct: 241 RLSRRSCLTRIQRMLELMIYVQSATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSL 300

Query: 671 QPPSIARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFL 730
           QPPSIARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFL
Sbjct: 301 QPPSIARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFL 360

Query: 731 VLLTLFVRFEFGHLSDVELLQLKVDSTKISTGEYVELRRTVVCVSFVLCPLFGTGNFASI 790
           VLLTLFVRFEFGHLSDVELLQLKVDSTKISTGEYVELRRTVVCVSFVLCPLFGTGNFASI
Sbjct: 361 VLLTLFVRFEFGHLSDVELLQLKVDSTKISTGEYVELRRTVVCVSFVLCPLFGTGNFASI 420

Query: 791 NSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQESIQRLCCFSLIF 850
           NSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQESIQRLCCFSLIF
Sbjct: 421 NSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQESIQRLCCFSLIF 480

Query: 851 TDFMSMCFFHQLRDEGSWLDIGMSISQFIVSMCISLALLLLLSISSHLMAFEFRKFPGKR 910
           TDFMSMCFFHQLRDEGSWLDIGMSISQFIVSMCISLALLLLLSISSHLMAFEFRKFPGKR
Sbjct: 481 TDFMSMCFFHQLRDEGSWLDIGMSISQFIVSMCISLALLLLLSISSHLMAFEFRKFPGKR 540

Query: 911 NHQEIESISSRKLSDDESA 929
           NHQEIESISSRKLSDDESA
Sbjct: 541 NHQEIESISSRKLSDDESA 559
>ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
 gb|AAF24617.1|AC010870_10 (AC010870) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
          Length = 921

 Score =  537 bits (1371), Expect = e-151
 Identities = 200/635 (31%), Positives = 331/635 (51%), Gaps = 66/635 (10%)

Query: 2   SWKFLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDTF 61
           +W  ++  + +H V + SIFD+Y+ +P+VHG+ P      E PAKR+ ++ +DGLR D F
Sbjct: 44  TW-LVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKF 102

Query: 62  NKYPD----KSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKK 117
            +  +    ++P+L +I+   +G +G+S +  PTESRPGHVAI AG  ED SAV KGWK 
Sbjct: 103 FEPDEEGKYRAPFLRNIIK-NQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKA 161

Query: 118 NPVQFDSVFNRSSYSWMWGSPDIVNLF-DDLPNAESFSYSADEEDFASKDASNLDKWVFE 176
           NPV+FDSVFN+S +++ +GSPDI+ +F   LP++   SY  + EDFA+ DAS LD+W F+
Sbjct: 162 NPVEFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTWNSYPHEYEDFAT-DASFLDEWSFD 220

Query: 177 HFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEK 236
            FE  L  +  D  L + + + K + FLHLLG D+NGH ++P S  Y++N+KVVD   E+
Sbjct: 221 QFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAER 280

Query: 237 VQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGGP------ 290
           V HL++ ++ D++T+++FT+DHGM+D GSHG G      TP VAWGAG++   P      
Sbjct: 281 VYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSH 340

Query: 291 ---------------------------KLDLNQIDLAPLISALIGCPIPVNSMGILPVQM 323
                                      ++D+NQ D+APL+S L+G P PVNS+G LP+  
Sbjct: 341 SDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGY 400

Query: 324 MNSKGSSYEFKAIEANFKQLKEQIIFLKNAKSR-RLWFRQFEKFGDKAMESLRTTLAQLG 382
           M     + E +A+ AN KQ+  Q++     KS   L+F+ F+     +     + + +L 
Sbjct: 401 MKLN-EAEEVEAVVANTKQILNQLLRKSYIKSSNSLFFKPFKPLVHHSFS--LSQIDELI 457

Query: 383 RDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIALVVSFLHNSTSKE 442
             + +  A  L  D  +L  E + ++  YD  ML   ++  +  W+ ++   +    S  
Sbjct: 458 SAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSSL 517

Query: 443 NLSLLVPHHLFIIPLACSLLFTAY------CSLSMTQTIYIILPIYLISILENHSKLTQR 496
           +  L    HL +    C  L                   YI + ++L + + +  +L + 
Sbjct: 518 SGDLSKKEHLSVYISGCL-LMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRLIRG 576

Query: 497 IREHVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAVFVLLMA 556
           + ++++   A           + F+K         + + + V +F +R      F++   
Sbjct: 577 LWKYLRERRA-----------DYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFLIAGV 625

Query: 557 LPQFYSHPIVSYWSKTWLTLCL---VLCIFPFLPA 588
           +     H  + + S   + +C+    L +F  +PA
Sbjct: 626 VASILLHFSIPWRSGIPVFVCISCWFLSVFTLMPA 660
 Score =  302 bits (767), Expect = 2e-80
 Identities = 103/437 (23%), Positives = 176/437 (39%), Gaps = 64/437 (14%)

Query: 530 FSITICIFVLTFMDRAFLAAVFVLLMALPQFYSHPIVSYWSKTWLTLCLVLCIFPFLPAV 589
           + + + +  L +     +     +L                  +++ CL++ I   L  V
Sbjct: 488 WLMLMTVITLGYTG-WMIVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLV 546

Query: 590 GVSTHIPLCILSPIITAFL-CHRLSRRSCL---------TRIQRMLELMIYVQSATAFMI 639
             S   PL      +T FL     S    +          R    ++L+     A   + 
Sbjct: 547 EHSP--PLYHAYIGMTVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVE 604

Query: 640 AVVN-------YGFEKVKKLIQNNWKKKKSNSKSSQSLQPPSIARWI--SWTSIPL---- 686
            +V+       Y +  +   +  +     S    S       I+ W    +T +P     
Sbjct: 605 LLVHSFTERKLYTWFFLIAGVVASILLHFSIPWRSGIPVFVCISCWFLSVFTLMPAEIPD 664

Query: 687 --SVIAPSLLTGP------------YLVDRLI-----AYALCFYVPYSLLSISYESLFML 727
             ++++P L                  VD+          +     + L+S  YE++F  
Sbjct: 665 NNNLVSPFLGANDTDIFGWCVICDGVFVDKASNAESRIAFVT--SVHKLVSCRYEAVFYS 722

Query: 728 IFLVLLTLFVRFEFG--HLSDVELLQLKVDSTK--------ISTGEYVELRRTVVCVSFV 777
              V+L  ++ FE    H S V+   L  ++T+            +  ++R  +V +   
Sbjct: 723 ALAVVLMAWILFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMVLF 782

Query: 778 LCPLFGTGNFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQ 837
               FGTGNFASI SF  S++  FI++FSPF MA LLI KL IP +LV  AF++I +  +
Sbjct: 783 NVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKLVR 842

Query: 838 ESIQRLCCFSLIF--TDFMSMCFFHQLRDEGSWLDIGMSISQF-IVSMCISLALLLLLSI 894
             + RL C+ L+   +D M++ FF  +++ GSW++IG SIS F IVS  +   LLL    
Sbjct: 843 --VPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVSAQVVFVLLLF--A 898

Query: 895 SSHLMAFEFRKFPGKRN 911
            ++L     R  P   +
Sbjct: 899 LTNLYTRSIRIKPLSTS 915
>dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [Mus musculus]
          Length = 391

 Score =  482 bits (1228), Expect = e-134
 Identities = 177/391 (45%), Positives = 252/391 (64%), Gaps = 34/391 (8%)

Query: 5   FLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDTFNK- 63
           F    + +H V   SIFD+Y+TSPLVHG+ PQF      PAKR+ +  ADGLR DT  + 
Sbjct: 4   FFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFT-PLPPPAKRLVLFVADGLRADTLYEL 62

Query: 64  ---YPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPV 120
                 ++P++ +++   +G +G+S + +PTESRPGHVA+ AG  ED+SAVAKGWK+NPV
Sbjct: 63  DEDGNSRAPFIRNVI-MHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121

Query: 121 QFDSVFNRSSYSWMWGSPDIVNLFDDLPNAE---SFSYSADEEDFASKDASNLDKWVFEH 177
           +FDS+FN S Y+W WGSPDI+ +F    + +   ++SY A  EDF + DA+ LD WVF+ 
Sbjct: 122 EFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWVFDK 181

Query: 178 FENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKV 237
            ++F + A+ +++L  K+ E+K +FFLHLLGIDTNGH ++P SR+Y DNIK VD G++++
Sbjct: 182 VKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEI 241

Query: 238 QHLVDAFFGDH-KTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQG-------- 288
             +   F+GD  KTA++FTSDHGMTDWGSHGAG   E LTPFV WGAG+K          
Sbjct: 242 VSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQY 301

Query: 289 ------------GPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAI 336
                         + D+NQ D+APL+++LIG P P+NS+GILPV  +N+ G  ++ +++
Sbjct: 302 DDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGL-FKAESM 360

Query: 337 EANFKQLKEQII---FLKNAKSRRLWFRQFE 364
             N  Q+ EQ       K   +    F  F+
Sbjct: 361 FTNAVQILEQFKVKMTQKKEATLPFLFTPFK 391
>ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans]
          Length = 348

 Score =  470 bits (1197), Expect = e-131
 Identities = 342/343 (99%), Positives = 343/343 (99%)

Query: 1   MSWKFLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDT 60
           MSWKFLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDT
Sbjct: 1   MSWKFLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDT 60

Query: 61  FNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPV 120
           FNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPV
Sbjct: 61  FNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPV 120

Query: 121 QFDSVFNRSSYSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASNLDKWVFEHFEN 180
           QFDSVFNRSSYSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASNLDKWVFEHFEN
Sbjct: 121 QFDSVFNRSSYSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASNLDKWVFEHFEN 180

Query: 181 FLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHL 240
           FLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHL
Sbjct: 181 FLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHL 240

Query: 241 VDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGGPKLDLNQIDLA 300
           VDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGGPKLDLNQIDLA
Sbjct: 241 VDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGGPKLDLNQIDLA 300

Query: 301 PLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEANFKQL 343
           PLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEANFKQ+
Sbjct: 301 PLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEANFKQV 343
>gb|AAF54658.1| (AE003692) CG5342 gene product [Drosophila melanogaster]
          Length = 559

 Score =  447 bits (1138), Expect = e-124
 Identities = 119/632 (18%), Positives = 219/632 (33%), Gaps = 101/632 (15%)

Query: 279 VAWGAGVKQGGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEA 338
           +A  AG++   P   LN   L  L+SAL+G P PV S G+LP  M+N+    YE  A+  
Sbjct: 1   MANEAGLR--LPLHVLNTPHLTALMSALLGVPPPVYSRGMLPKGMLNA-SLRYEANAMLI 57

Query: 339 NFKQLKEQIIFLKNAKSRRL--WFRQFEKFGDKAMESLRTTLAQLGRDRRFSVATSLFAD 396
           N KQL  Q   L+    +R+  ++  F+   +   ESL      L + RRF        +
Sbjct: 58  NAKQLLAQARRLRELHPKRMPAFWLSFQMMDNFVKESL-----ALKKQRRFRALLDYSCN 112

Query: 397 NAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIALVVSFLH-----NSTSKENLSLLVPHH 451
              ++ + + ++  Y R +   AVS + +AWI  +   L       +  +    +     
Sbjct: 113 YMPVLIKGMDYFKDYYRHVSITAVSFAGIAWIYCLRCHLTVGKKCRNLIEIQEVISSKRL 172

Query: 452 LF-----IIPLACSLLFTAYCSLSMTQTIYIILPIYLISILENHSKLTQRIREHVKALSA 506
           ++      +     ++      + +     +++P                 R  +K L  
Sbjct: 173 VYARGFHRLLTGVLVIIMMLERIPLVVQAILLIPSLYW-------------RTTLKILGE 219

Query: 507 QPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAVFVLLMALPQFYSHPIV 566
           +P  + +   +   +   + F G           F  R  LA  ++   +     +    
Sbjct: 220 RPKMVCRKSLMSTALLALICFGG-----------FFRRYILAVGYLGFASYNNREAFKRR 268

Query: 567 SYWSKTWLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFLCHRLSRRSCLTRIQRMLE 626
            +    WL L L L +   LP     +     + S  +T            L      + 
Sbjct: 269 GHQFYLWLLLLLGLTVVSALPESLGCSQPGALMFSIFLTVLRPLACGVYLNLLTWLSNIP 328

Query: 627 LMIYVQSATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSLQPPSIARWISWTSIPL 686
           +++                     + I   W               P I   +SW  +  
Sbjct: 329 VLLAAL------------------EYILIGWH--------------PWIMYLVSWIYLGF 356

Query: 687 SVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFLVLLTLFVRFEFGHLSD 746
            V+          +     +       Y+L   SYES+ + +  + L L +R +      
Sbjct: 357 LVLWQRRN-----LQASEVFFFDLSTLYTLTCTSYESVVIQMLAMELQLALRMK------ 405

Query: 747 VELLQLKVDSTKISTGEYVELRRTVVCVSFVLCPLFGTGNFASINSF-NPSTLNLFISVF 805
              L+        +   Y         + +    LF  G+F + + F +      F   +
Sbjct: 406 ---LKRNESIGPKTAAHY--------ILVYSWYSLFIIGSFPAFDDFLDILHETCF--GY 452

Query: 806 SPFTMAILLILKLLIPILLVTSAFASIVRFDQESIQRLCCFSLIFTDFMSMCFFHQLRDE 865
           SP T  ++++LKL++P LLV    A   +      Q++    L+    MS+   H + + 
Sbjct: 453 SPLTYGLVMVLKLILPWLLVLCIMAGNYKSLASYEQQIFVRLLLMNSAMSLVLLHGITNV 512

Query: 866 GSWLDIGMSISQFIVSMCISLALLLLLSISSH 897
           G W DI    ++F V     L  LLL  ++  
Sbjct: 513 GPWRDILSRFAEFAVVHVFPLVWLLLWRLTQL 544
>ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) biosynthesis; Gpi13p
           [Saccharomyces cerevisiae]
 pir||S64782 probable membrane protein YLL031c - yeast (Saccharomyces
           cerevisiae)
 emb|CAA97480.1| (Z73136) ORF YLL031c [Saccharomyces cerevisiae]
          Length = 1017

 Score =  429 bits (1092), Expect = e-118
 Identities = 85/599 (14%), Positives = 180/599 (29%), Gaps = 92/599 (15%)

Query: 5   FLIASITVHLVLIYSI----FDVYYTSPLVHGIPPQFINSQEAP-AKRIFIISADGLRYD 59
           ++I  + + ++   SI         +  ++  I  Q   S+  P   +  I+  D LR+D
Sbjct: 35  YIILLVFIAILQFISIAFFTRGFLLSRHVLDNISSQNETSKLPPRFNKAVILVIDALRFD 94

Query: 60  TFNKYPD-----KSPYLHSIM---------NERKGIYGLSRSHIPTESRPGHVAIFAGIT 105
                 +        Y ++I+          +   +     +  PT +      +  G  
Sbjct: 95  FAIPVNESHSNYNLNYHNNILSLYDSFASDKDASSLLLKFIADPPTTTLQRLKGLTTGSL 154

Query: 106 EDISAVAKGWKKNPVQFDSVFNR---SSYSWMW-GSPDIVNLFDDLPNAESFSYSADEED 161
                    +    ++ D+   +   ++ +  + G    + LF    + +SF      E 
Sbjct: 155 PTFIDAGSNFDGTVIEEDNFLKQLHLANKTVKFAGDDTWMALFHPFLSNDSF----PLES 210

Query: 162 FASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSR 221
               D   +D  V ++F +           + +  ++  +   H+LGID  GH   P   
Sbjct: 211 LNVWDLDTVDNGVMDYFHD-----------HLQQDKEWDVMIGHMLGIDHVGHKYGPDHF 259

Query: 222 QYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAW 281
              +    VD  I+ +   +     D  T  +   DHGM   G+HG  S DE+ +    +
Sbjct: 260 TMREKQIQVDQFIDWILKSI-----DDDTLLVILGDHGMDHTGNHGGDSIDELESTLFLY 314

Query: 282 GAGVKQ--------------GGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSK 327
                               G     + QIDL   ++ L+G PIP N++G    ++  + 
Sbjct: 315 SKKPDMWRLKETSNYNIDNLGHDYRSVRQIDLVSSLALLMGQPIPFNNLGWPIDEIARND 374

Query: 328 GSSYEFKAIEANFKQLKEQIIFLKNAKS--RRLWFRQFEKFGDKAMESLRTTLAQLGRDR 385
               +F     +     +              +     +   +    S      +LG   
Sbjct: 375 REWSQF---VNSAISQLQLYKDTMQIHHGNDEILEPLAKNISNTPPTSDPEKFVKLGHKY 431

Query: 386 RFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIALVVSFLHNSTSKENLS 445
           +  V      +          +Y          A   + +A   +++  +        ++
Sbjct: 432 QK-VFLQTCEEL----WAKFDYYS--------IATGITLLATSLVLLISITKLIPSIVVN 478

Query: 446 LLVPHHLFIIPLACS-------LLFTAYCSLSMTQTIYIILP-------IYLISILENHS 491
            +VP  +  I +           +F  Y   S     +  L        I     + +  
Sbjct: 479 QMVPEFVPGIIIMVLVTNLCFHGIFYVYQQPSFVDQFWGTLLATAIGIIIGCYITIFDRY 538

Query: 492 KLTQRIREHVKALSA-QPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAA 549
                     + L+          + +   +     F  +   I  F+L+      L  
Sbjct: 539 NFIWIAMRLGETLADYWSRIAVMFMIIHALLFTSNSFTIWEDRIVAFLLSTFG--MLTL 595
>pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast
           (Schizosaccharomyces pombe)
 dbj|BAA21454.1| (AB004539) ORF YLL031c [Schizosaccharomyces pombe]
 emb|CAA16901.1| (AL021766) hypothetical protein [Schizosaccharomyces pombe]
          Length = 918

 Score =  421 bits (1072), Expect = e-116
 Identities = 111/594 (18%), Positives = 198/594 (32%), Gaps = 91/594 (15%)

Query: 2   SWKFLIASITVHLVLIYSIFD-------------VYYTSPLVHGIPP---QFINSQEAPA 45
           +WK++ A I   ++LI + +              V   + L    P    ++ NS    A
Sbjct: 18  TWKYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWA 77

Query: 46  K----RIFIISADGLRYDTFNKYPDK--------SPYLHSIMNERKGIYGLSRSHIPTES 93
                R  I+  D LRYD    Y D         +PY  S+++          +  PT +
Sbjct: 78  PKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTT 137

Query: 94  RPGHVAIFAGITEDISAVAKGWKKNPVQFDSVFNR----SSYSWMWGSPDIVNLFDDLPN 149
                 +  G       +   +    +  D++  +         + G      LF D  N
Sbjct: 138 SQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSLDKQIVLLGDDTWDVLFHDYLN 197

Query: 150 AESFSYSADEEDFASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGI 209
                 S     F   D   +D  V ++  ++++ A               +   H LG+
Sbjct: 198 ETL---SQPAFSFNVPDLHGVDNKVNQYVFDYIKDANF------------DVLIAHYLGV 242

Query: 210 DTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAG 269
           D  GH   P      D +  +D  ++++  L+     D  T  +   DHGM + G+HG  
Sbjct: 243 DHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL-----DDSTLLIVMGDHGMDNKGNHGGD 297

Query: 270 SDDEVLTPFVAWGAGV-----KQGGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMM 324
           S DE+ +    +         KQ G  L  NQ+DL P +S L+G PIP  ++G L  +  
Sbjct: 298 SFDEINSVLWMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEPF 357

Query: 325 NSKGSSYEFKAIEANFKQLKEQIIFLKNAKSRRLWFRQFEKF-GDKAMESLRTTLAQLGR 383
              G  Y  KA + N  QL               +F +++    D    S+         
Sbjct: 358 YYYGDEYLSKAQKINIGQLNR-------------FFSEYDLDASDFLSSSVHKNNNSYLD 404

Query: 384 DRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIA----LVVSFLHNST 439
                     +  +    ++A  ++     +     +   F+  I     L +     S 
Sbjct: 405 Q---------YFLDFDYARDAFSYFKAIWAEFSLFPMIIGFLLLIIGGFNLALLMQDKSV 455

Query: 440 SKENLSLLVPHHLFIIPLACSLLFTAY--CSLSMTQTIYIILPIYLISILENHSKLTQRI 497
                + + P  +      C +L  A            Y++LP +   IL N     Q++
Sbjct: 456 IFRMSANMAPS-VMKCLPVCLILILANNELHSPFPAEFYVLLPSF--YILLNSFN--QKL 510

Query: 498 REHVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAVF 551
            E+ K       +   +  + V       F  +   +C F++  +        F
Sbjct: 511 MEYFKGFVKLDYFSIFITFLHVCSFGSNSFTVWEDRLCHFLIITIGLVMFCKCF 564
>dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:1351629,
           evidence:ISS~phosphatidylinositol glycan, class
           N~putative [Mus musculus]
          Length = 320

 Score =  397 bits (1010), Expect = e-109
 Identities = 147/292 (50%), Positives = 204/292 (69%), Gaps = 10/292 (3%)

Query: 5   FLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDTFNK- 63
           F    + +H V   SIFD+Y+TSPLVHG+ PQF      PAKR+ +  ADGLR DT  + 
Sbjct: 4   FFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFT-PLPPPAKRLVLFVADGLRADTLYEL 62

Query: 64  ---YPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPV 120
                 ++P++ +++   +G +G+S + +PTESRPGHVA+ AG  ED+SAVAKGWK+NPV
Sbjct: 63  DEDGNSRAPFIRNVI-MHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121

Query: 121 QFDSVFNRSSYSWMWGSPDIVNLFDDLPNAE---SFSYSADEEDFASKDASNLDKWVFEH 177
           + DS+FN   Y+W WGSPDI+ +F    + +   ++SY A  EDF + DA+ LD WVF+ 
Sbjct: 122 ESDSLFNERKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWVFDK 181

Query: 178 FENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKV 237
            ++F + A+ +++L  K+ E+K +FFLHLLGIDTNGH ++P SR+Y DNIK VD G++++
Sbjct: 182 VKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEI 241

Query: 238 QHLVDAFFGDH-KTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQG 288
             +   F+GD  KTA++FTSDHGMTDWGSHGAG   E LTPFV WGAG+K  
Sbjct: 242 VSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFP 293
>gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melanogaster]
          Length = 880

 Score =  351 bits (893), Expect = 3e-95
 Identities = 107/504 (21%), Positives = 173/504 (34%), Gaps = 56/504 (11%)

Query: 1   MSWKFLIASITVHLVLIYSIFDVYYTSPLVHG--IPPQFINSQEAP---AKRIFIISADG 55
           M   FL  ++   +    + + V      V               P        ++  D 
Sbjct: 14  MLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSFVLLLVDA 73

Query: 56  LRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGW 115
           LR D         P  +S   E+          IPT + P   +I  G   +   +A   
Sbjct: 74  LRDDF--PDATSMPVAYSRACEKL----KLHVDIPTVTMPRLKSITTGTLSNFIDIALNV 127

Query: 116 KKNPVQFDSVFNRSSY----SWMWGSPDIVNLFDDLPNAESFSYSADEED-FASKDASNL 170
                  DS  +R           G    V LF        F+   +  D F   D    
Sbjct: 128 GHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFP-----SEFTRQVENHDSFYVNDFYEG 182

Query: 171 DKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVV 230
           D+ V +  E  LE +              S+  LH LG+D  GH     S +    +K +
Sbjct: 183 DRNVTKTLETELERS------------DWSLLILHYLGLDHIGHVEGNASPRVPLKLKEM 230

Query: 231 DSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPF-VAWGAGVKQGG 289
           D  ++K+     +F        + T DHGM D G HG  +  E L P  + +    K   
Sbjct: 231 DEVVKKILDH-KSFPN---VLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNNCSKTPS 286

Query: 290 PKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEANFKQLK--EQI 347
                NQIDLAP +S L+   IP  S+G L  +M+ S    ++  A   N   L    ++
Sbjct: 287 ASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLLNKARV 346

Query: 348 IFLKNAKSRRLWFRQFEKFGDKAMESLRTTLAQLGRDRRFSVATSLFADNAHLMKEAIVF 407
            F      R  ++  ++         L   L +  R+     A+ ++  NA L       
Sbjct: 347 KFGHEIVHRSDYYTWYQN-----ATLLHKKLLRPLREGDGGGASQVYYQNAKLN------ 395

Query: 408 YHRYDRQMLGAAVSCSFVAWIALVVSFLHNSTSKENLSLLVPHHLFIIPLACSLLFTAYC 467
           Y R   Q+ G  V      W++++ + + N TS     ++    L+ I L   +    Y 
Sbjct: 396 YMRL--QLDGLKV---GQLWLSVIAAVVLNYTSHALDIIMTSSTLYSILLLVPISIAVYL 450

Query: 468 SLSMTQTIYIILPIYLISILENHS 491
           ++ + Q +  I    L +     S
Sbjct: 451 TIDVAQALLKIALPPLYTRRLKIS 474
>gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarrowia lipolytica]
          Length = 860

 Score =  330 bits (838), Expect = 7e-89
 Identities = 81/386 (20%), Positives = 137/386 (34%), Gaps = 53/386 (13%)

Query: 1   MSWKFLIASITVHLVLIYSIF----DVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGL 56
           M WK    ++T+ ++ + ++         +  L+ G   +   S EAP ++  I+  D  
Sbjct: 1   MLWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYT-ESRVSTEAPFQKAIIMVVDAF 59

Query: 57  RYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWK 116
           R D         P LH  +N    I   + S  PT + P    +  G T +         
Sbjct: 60  RSDFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIA 119

Query: 117 -----KNPVQFDSVFNRS----SYSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDA 167
                      DS   ++        M+G    + LF        F        F   D 
Sbjct: 120 ESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFP-----GMFDDCEGTASFFVSDY 174

Query: 168 SNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNI 227
           + +D  V  H +  L+            + +  +  LH LG+D  GH   P S       
Sbjct: 175 TEVDNNVTRHIDTQLDQ-----------KTEWDVLILHYLGLDHIGHKTGPESPFMPAKQ 223

Query: 228 KVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQ 287
           K +D   +K+ +       D  T  +   DHGM + G+HG  S  E     V      + 
Sbjct: 224 KEMDDIFDKLYNSC-----DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFET 278

Query: 288 ----------GGPKLD-------LNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSS 330
                       P  D       ++Q DL P ++AL+G   P N++G+L  QM+      
Sbjct: 279 AQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSPE 338

Query: 331 YEFKAIEANFKQLKEQIIFLKNAKSR 356
            +   ++ N  Q+  QI+  + ++  
Sbjct: 339 DQLNVLKNNADQMV-QILQGQASRES 363
>pir||T02245 hypothetical protein P1.11659_3 - human
 gb|AAC07985.1| (AC004472) P1.11659_3 [Homo sapiens]
          Length = 880

 Score =  330 bits (838), Expect = 9e-89
 Identities = 61/359 (16%), Positives = 119/359 (32%), Gaps = 51/359 (14%)

Query: 32  GIPPQFINSQEAPAKRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHIPT 91
           G P     +      R+ ++  D LR+D           L   +         S+   PT
Sbjct: 56  GKPGACWMASR--FSRVVLVLIDALRFDFAQP-QHSHRILE--IQPHHARLYRSQVDPPT 110

Query: 92  ESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSVFNR----SSYSWMWGSPDIVNLFDDL 147
            +     A+  G           +  + +  D++  +           G     +LF   
Sbjct: 111 TTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDDTWKDLFP-- 168

Query: 148 PNAESFSYSADEEDFASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLL 207
               +FS +     F  +D   +D  + EH    +++             +  +   H L
Sbjct: 169 ---GAFSKAFFFPSFNVRDLDTVDNGILEHLYPTMDSG------------EWDVLIAHFL 213

Query: 208 GIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHG 267
           G+D  GH + P   +    +  +D  I+ +   ++     + T  +   DHGMT  G HG
Sbjct: 214 GVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLE-----NDTLLVVAGDHGMTTNGDHG 268

Query: 268 AGSDDEVLTPFVAWGAGVKQGGPKLD----LNQIDLAPLISALIGCPIPVNSMGILPVQM 323
             S+ EV      +           +    + Q+ L P ++ L+G PIP  ++G +  ++
Sbjct: 269 GDSELEVSAALFLYSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAEL 328

Query: 324 MNSKGSSY-------EFKAIEANFKQLKE---------QIIFLKNAKSRRLWFRQFEKF 366
            +    S        +  A+  N +Q+           Q +  K     +  F +    
Sbjct: 329 FSGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASAD 387
>ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involved in the attachment
           of glycosylphosphatidylinositol (GPI) anchors to
           proteins.; Las21p [Saccharomyces cerevisiae]
 sp|P40367|YJG2_YEAST HYPOTHETICAL 94.9 KD PROTEIN IN MRPL8-NUP82 INTERGENIC REGION
 pir||S50810 probable membrane protein YJL062w - yeast (Saccharomyces
           cerevisiae)
 emb|CAA84061.1| (Z34288) HRC830 [Saccharomyces cerevisiae]
 emb|CAA89353.1| (Z49337) ORF YJL062w [Saccharomyces cerevisiae]
          Length = 830

 Score =  328 bits (833), Expect = 3e-88
 Identities = 83/471 (17%), Positives = 150/471 (31%), Gaps = 83/471 (17%)

Query: 5   FLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEA-----PAKRIFIISADGLRYD 59
           F   S    L ++  IF  +    ++ GI  Q  +         P +++  +  D LR D
Sbjct: 6   FTCLSCAQLLAILLFIFAFFPRKIVLTGISKQDPDQDRDLQRDRPFQKLVFVIIDALRSD 65

Query: 60  TFNKYP-DKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKK- 117
                       +H  +N  +     S ++ PT + P   +I  G T     +     + 
Sbjct: 66  FLFDSQISHFNNVHQWLNTGEAWGYTSFANPPTVTLPRLKSITTGSTPSFIDLLLNVAQD 125

Query: 118 ----NPVQFDSVFNRS---SYSW-MWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASN 169
               +  + DS   +    + +    G    + LF      + F ++     F   D + 
Sbjct: 126 IDSNDLSEHDSWLQQFIQHNNTIRFMGDDTWLKLFPQ----QWFDFADPTHSFFVSDFTQ 181

Query: 170 LDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKV 229
           +D  V  +    L           +   Q  +  LH LG+D  GH + P S+      + 
Sbjct: 182 VDNNVTRNLPGKL----------FQEWAQWDVAILHYLGLDHIGHKDGPHSKFMAAKHQE 231

Query: 230 VDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGG 289
           +DS ++ +   V     D  T      DHGM + G+HG  S  E     +     + Q  
Sbjct: 232 MDSILKSIYDEVLEHEDDDDTLICVLGDHGMNELGNHGGSSAGETSAGLLFLSPKLAQFA 291

Query: 290 ---------------------PKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKG 328
                                    + QID+ P I+AL G PIP+NS+GI+    +    
Sbjct: 292 RPESQVNYTLPINASPDWNFQYLETVQQIDIVPTIAALFGMPIPMNSVGIIIPDFLQLLP 351

Query: 329 SSYEFKAIEANFKQLKEQIIFLKNAKSRRLWFRQFEKFGDKAMESLRTTLAQLGRDRRFS 388
           +  +  +++ NF  L                  +     D   E + T            
Sbjct: 352 N--KLASMKENFMHL----------WKLSDHHGEVALD-DFTAEDIYTK----------- 387

Query: 389 VATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIALVVSFLHNST 439
                     + ++E +          L       F+    + +  L   +
Sbjct: 388 ---------MYTIQETLTKSATNYNYPLLTLAFVGFLIITIIAIYVLLRYS 429
>ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class O [Mus musculus]
 dbj|BAA96254.1| (AB038560) Pig-o [Mus musculus]
          Length = 1101

 Score =  313 bits (795), Expect = 8e-84
 Identities = 66/375 (17%), Positives = 120/375 (31%), Gaps = 65/375 (17%)

Query: 31  HGIPPQFINSQEAPAKRIFIISADGLRYDTFNKYPDK--------SPYLHSI-------- 74
           HG P            R+ ++  D LR+D                 P+L  +        
Sbjct: 63  HGKPGACWMPSR--FSRVVLVLIDALRFDFAQPQRSHVPGEPPVSVPFLGKLGSLQRILE 120

Query: 75  MNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSVFNR----SS 130
                G    S+   PT +     A+  G           +  + +  D+V  +      
Sbjct: 121 SQPHHGRLYRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNVIQQLNSAGR 180

Query: 131 YSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASNLDKWVFEHFENFLETAKTDEA 190
                G     +LF       +FS +     F  +D   +D  + EH    L+       
Sbjct: 181 RVVFMGDDTWRDLFP-----GAFSQAFFFSSFNVRDLHTVDNGILEHLYPTLDGG----- 230

Query: 191 LNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKT 250
                     +   H LG+D  GH + P   +    +  +D  I+ +   ++     + T
Sbjct: 231 -------SWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLIERLE-----NDT 278

Query: 251 AWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGGPKLD----LNQIDLAPLISAL 306
             +   DHGMT  G HG  S+ EV      +           +    + Q+ L P ++ L
Sbjct: 279 LLVVAGDHGMTMNGDHGGDSELEVSAALFLYSPTALFPSVPPEEPEVIPQVSLVPTLALL 338

Query: 307 IGCPIPVNSMGILPVQMMNSKGSSY--------EFKAIEANFKQLKE---------QIIF 349
           +G PIP  + G +  ++ +    S         +  A+  N +Q+           Q + 
Sbjct: 339 LGLPIPFGNTGEVMAELFSGGSDSSHPHSSALAQVSALHINAQQVSRFLHTYSAATQDLQ 398

Query: 350 LKNAKSRRLWFRQFE 364
           +K     +  F +  
Sbjct: 399 VKELHRLQTLFSKAS 413
>ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thaliana]
 gb|AAF18652.1| (AC006592) unknown protein [Arabidopsis thaliana]
          Length = 897

 Score =  313 bits (795), Expect = 1e-83
 Identities = 77/386 (19%), Positives = 137/386 (34%), Gaps = 52/386 (13%)

Query: 2   SWKFLIASITVHLV-LIYSIFDVYYTSPLVHGIPPQFINSQE---------------APA 45
              F +A I + ++ L   +F  +   P + G+                           
Sbjct: 11  LTIFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEK 70

Query: 46  KRIFIISADGLRYDTFNKYP---------DKSPYLHSIMNERKGIYGLSRSHIPTESRPG 96
            R+     DGL  +               +  PY  S++     I   +++  PT + P 
Sbjct: 71  LRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPR 130

Query: 97  HVAIFAGITEDISAVAKGWKKNPVQFDSVFNRSSY----SWMWGSPDIVNLFDDLPNAES 152
             A+ +G       VA  +    +  D++  +         M G    + LF        
Sbjct: 131 LKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFP-----GL 185

Query: 153 FSYSADEEDFASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTN 212
           F        F  KD   +D+ V  H  + L +            +  ++  LH LG+D  
Sbjct: 186 FMRHDGVSSFFVKDTVQVDRNVSRHLPDELNS------------DDWNLLILHYLGLDHV 233

Query: 213 GHGNKPMSRQYIDNIKVVDSGIEKVQ--HLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGS 270
           GH     S      +K +D  +  +    ++D      +T  +  SDHGMT+ G+HG  S
Sbjct: 234 GHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSS 293

Query: 271 DDEVLTPFV---AWGAGVKQGGPKLDLN-QIDLAPLISALIGCPIPVNSMGILPVQMMNS 326
            +E  +  +                ++  Q+DLAP ++ L G PIP N++G+L    + S
Sbjct: 294 YEETDSLMLFIGLNSNISDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCS 353

Query: 327 KGSSYEFKAIEANFKQLKEQIIFLKN 352
                + +A+E N  QL   ++    
Sbjct: 354 LRDFEQLRALELNSWQLLRLMLAQIQ 379
>gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melanogaster]
          Length = 1077

 Score =  288 bits (730), Expect = 3e-76
 Identities = 65/342 (19%), Positives = 124/342 (36%), Gaps = 47/342 (13%)

Query: 43  APAKRIFIISADGLRYDTFN---KYPDKSPYLHSIM--------NERKGIYGLSRSHIPT 91
               ++ ++  D L+Y+         D  PY + ++        N         R+  PT
Sbjct: 74  PQKSKVIVLVVDALKYEFGLYRANATDPLPYENKLVVLQELLQQNPDHARLMRFRADPPT 133

Query: 92  ESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSVFNRSS----YSWMWGSPDIVNLFDDL 147
            +      +  G       +   +    +  D++ ++           G     +L+   
Sbjct: 134 TTLQRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQIVKNDLPVVFLGDSTWTDLYPH- 192

Query: 148 PNAESFSYSADEEDFASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLL 207
                F  S     F   D  ++D  + +H    LE+            +   +   H L
Sbjct: 193 ----RFKRSYSYPSFDIFDLDSVDNEILKHLPKELES------------KDWQVLVAHFL 236

Query: 208 GIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHG 267
           G+D  GH + PM  +    +  ++  I  V   +     D+ T  L   DHGMT  G HG
Sbjct: 237 GVDHCGHKHGPMHEEMARKLGEMNEVIRSVVAAM-----DNDTTLLVMGDHGMTASGDHG 291

Query: 268 AGSDDEVLTPFVAWGA-----GVKQGGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQ 322
             +DDE      A+       G   G     L QIDL P ++ ++G PIP +++G++   
Sbjct: 292 GDTDDETNALLFAYSKQHRFYGNDSGSDSEMLQQIDLVPTLATILGVPIPYSNLGLVNFN 351

Query: 323 MMNSKGSSY--EFKAIEANFKQLKEQ---IIFLKNAKSRRLW 359
           ++      +  +F+ +  +  Q  +Q     F    +++R +
Sbjct: 352 IVPDLRVPHLNKFQTLLLHSWQNAQQIYRYFFQYALENKRTF 393
>ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]
 gb|AAB93646.1| (AF003137) Hypothetical protein C27A12.9 [Caenorhabditis elegans]
          Length = 905

 Score =  285 bits (723), Expect = 3e-75
 Identities = 72/352 (20%), Positives = 124/352 (34%), Gaps = 51/352 (14%)

Query: 7   IASITVHLVLIYSIF--DVYYTSPLVHGIPPQFIN----SQEAPAK----RIFIISADGL 56
           I  ++++++L   IF          +              Q    K    R+ +I  D L
Sbjct: 7   ILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILILVDAL 66

Query: 57  RYDTFNKYPDK-------------SPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAG 103
           RYD      +                 +  ++       G   +  PT +     A+  G
Sbjct: 67  RYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTG 126

Query: 104 ITEDISAVAKGWKKNPVQ-FDSVFNRS----SYSWMWGSPDIVNLFDDLPNAESFSYSAD 158
                      +  + V   DS   ++        + G    ++LF        FS +A 
Sbjct: 127 TLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFP-----NQFSKTAA 181

Query: 159 EEDFASKDASNLD-----KWVFEHFENFLETAKTDEALNDKM-REQKSIFFLHLLGIDTN 212
            + F   D + +D     K  F  + N +        L D+M     SI   H LG+D  
Sbjct: 182 YDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHC 241

Query: 213 GHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDD 272
           GH   P      D ++ +D  I +    + +             DHGMT  G HG  S++
Sbjct: 242 GHKFGPSHPVMADTLRKMDRIIGQTIETMKS------------DDHGMTSTGDHGGESEN 289

Query: 273 EVLTPFVAWGAGVKQGGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMM 324
           E+    +      +   P+  ++QID+ P IS L+G PIP +++G +  Q+ 
Sbjct: 290 EIRAGILVHSKKHQIILPERPIHQIDIVPTISLLMGLPIPFSNLGTVITQLF 341
 Score =  281 bits (712), Expect = 5e-74
 Identities = 72/355 (20%), Positives = 125/355 (34%), Gaps = 53/355 (14%)

Query: 4   KFLIASITVHLVLIYSIF--DVYYTSPLVHGIPPQFIN----SQEAPAK----RIFIISA 53
           +  I  ++++++L   IF          +              Q    K    R+ +I  
Sbjct: 6   R--ILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILILV 63

Query: 54  DGLRYDTFNKYPDK-------------SPYLHSIMNERKGIYGLSRSHIPTESRPGHVAI 100
           D LRYD      +                 +  ++       G   +  PT +     A+
Sbjct: 64  DALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKAL 123

Query: 101 FAGITEDISAVAKGWKKNPVQ-FDSVFNRS----SYSWMWGSPDIVNLFDDLPNAESFSY 155
             G           +  + V   DS   ++        + G    ++LF        FS 
Sbjct: 124 TTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFP-----NQFSK 178

Query: 156 SADEEDFASKDASNLD-----KWVFEHFENFLETAKTDEALNDKM-REQKSIFFLHLLGI 209
           +A  + F   D + +D     K  F  + N +        L D+M     SI   H LG+
Sbjct: 179 TAAYDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGV 238

Query: 210 DTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAG 269
           D  GH   P      D ++ +D  I +    + +             DHGMT  G HG  
Sbjct: 239 DHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKS------------DDHGMTSTGDHGGE 286

Query: 270 SDDEVLTPFVAWGAGVKQGGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMM 324
           S++E+    +      +   P+  ++QID+ P IS L+G PIP +++G +  Q+ 
Sbjct: 287 SENEIRAGILVHSKKHQIILPERPIHQIDIVPTISLLMGLPIPFSNLGTVITQLF 341
>pir||A27410 plasma cell membrane glycoprotein PC-1 - mouse
          Length = 905

 Score =  257 bits (652), Expect = 5e-67
 Identities = 43/244 (17%), Positives = 83/244 (33%), Gaps = 18/244 (7%)

Query: 34  PPQFINSQEAPA----KRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHI 89
             + I++ E PA        + S DG R +  + +    P +  + N             
Sbjct: 176 TCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGT---YTKNMRP 232

Query: 90  --PTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSV----FNRSSYSWMWGSPDIVNL 143
             PT++ P H +I  G+  +   +      +P    S       + +  W  G P  V  
Sbjct: 233 MYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTA 292

Query: 144 FDDLPNAESFSYSADEEDFAS--KDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSI 201
                 + ++ +   + +      D   +        E  L   +    L     E+   
Sbjct: 293 NHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEW---LQLPSHERPHF 349

Query: 202 FFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMT 261
           + L+L   D++GH + P+S + I  ++ VD  +  +   +     D     +  SDHGM 
Sbjct: 350 YTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGME 409

Query: 262 DWGS 265
               
Sbjct: 410 QGSC 413
>ref|NP_032839.2| (NM_008813) phosphodiesterase I/nucleotide pyrophosphatase 1; 1
           ectonucleotide pyrophosphatase/phosphodiesterase 1 [Mus
           musculus]
 gb|AAA39893.2| (J02700) ecto-nucleotide pyrophosphatase/phosphodiesterase-1 [Mus
           musculus domesticus]
          Length = 905

 Score =  257 bits (652), Expect = 6e-67
 Identities = 43/244 (17%), Positives = 83/244 (33%), Gaps = 18/244 (7%)

Query: 34  PPQFINSQEAPA----KRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHI 89
             + I++ E PA        + S DG R +  + +    P +  + N             
Sbjct: 176 TCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGT---YTKNMRP 232

Query: 90  --PTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSV----FNRSSYSWMWGSPDIVNL 143
             PT++ P H +I  G+  +   +      +P    S       + +  W  G P  V  
Sbjct: 233 MYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTA 292

Query: 144 FDDLPNAESFSYSADEEDFAS--KDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSI 201
                 + ++ +   + +      D   +        E  L   +    L     E+   
Sbjct: 293 NHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEW---LQLPSHERPHF 349

Query: 202 FFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMT 261
           + L+L   D++GH + P+S + I  ++ VD  +  +   +     D     +  SDHGM 
Sbjct: 350 YTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGME 409

Query: 262 DWGS 265
               
Sbjct: 410 QGSC 413
>gb|AAK84174.1|AF339910_1 (AF339910) ectonucleotide pyrophosphatase/phosphodiesterase 1
           allotype b [Mus musculus]
          Length = 906

 Score =  257 bits (652), Expect = 6e-67
 Identities = 43/244 (17%), Positives = 83/244 (33%), Gaps = 18/244 (7%)

Query: 34  PPQFINSQEAPA----KRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHI 89
             + I++ E PA        + S DG R +  + +    P +  + N             
Sbjct: 176 TCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGT---YTKNMRP 232

Query: 90  --PTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSV----FNRSSYSWMWGSPDIVNL 143
             PT++ P H +I  G+  +   +      +P    S       + +  W  G P  V  
Sbjct: 233 MYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTA 292

Query: 144 FDDLPNAESFSYSADEEDFAS--KDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSI 201
                 + ++ +   + +      D   +        E  L   +    L     E+   
Sbjct: 293 NHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEW---LQLPSHERPHF 349

Query: 202 FFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMT 261
           + L+L   D++GH + P+S + I  ++ VD  +  +   +     D     +  SDHGM 
Sbjct: 350 YTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGME 409

Query: 262 DWGS 265
               
Sbjct: 410 QGSC 413
>sp|P06802|PC1_MOUSE Ectonucleotide pyrophosphatase/phosphodiesterase 1 (Plasma-cell
           membrane glycoprotein PC-1) [Includes: Alkaline
           phosphodiesterase I ; Nucleotide pyrophosphatase
           (NPPASE)]
          Length = 871

 Score =  255 bits (647), Expect = 2e-66
 Identities = 43/244 (17%), Positives = 83/244 (33%), Gaps = 18/244 (7%)

Query: 34  PPQFINSQEAPA----KRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHI 89
             + I++ E PA        + S DG R +  + +    P +  + N             
Sbjct: 142 TCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGT---YTKNMRP 198

Query: 90  --PTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSV----FNRSSYSWMWGSPDIVNL 143
             PT++ P H +I  G+  +   +      +P    S       + +  W  G P  V  
Sbjct: 199 MYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTA 258

Query: 144 FDDLPNAESFSYSADEEDFAS--KDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSI 201
                 + ++ +   + +      D   +        E  L   +    L     E+   
Sbjct: 259 NHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEW---LQLPSHERPHF 315

Query: 202 FFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMT 261
           + L+L   D++GH + P+S + I  ++ VD  +  +   +     D     +  SDHGM 
Sbjct: 316 YTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGME 375

Query: 262 DWGS 265
               
Sbjct: 376 QGSC 379
>ref|NP_445987.1| (NM_053535) ectonucleotide pyrophosphatase/phosphodiesterase 1
           [Rattus norvegicus]
 gb|AAK69654.1|AF340186_1 (AF340186) ecto-nucleotide pyrophosphatase/phosphodiesterase-1
           [Rattus norvegicus]
          Length = 906

 Score =  255 bits (647), Expect = 2e-66
 Identities = 42/243 (17%), Positives = 83/243 (33%), Gaps = 18/243 (7%)

Query: 35  PQFINSQEAPA----KRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHI- 89
            + I++ + PA        + S DG R +  + +    P +  + N              
Sbjct: 177 CETIDAPQCPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGT---YTKNMRPV 233

Query: 90  -PTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSV----FNRSSYSWMWGSPDIVNLF 144
            PT++ P H +I  G+  +   +      +P    S       + +  W  G P  V   
Sbjct: 234 YPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTAN 293

Query: 145 DDLPNAESFSYSADEEDFAS--KDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIF 202
                + ++ +   + +      D   +        E  L   +    L     E+   +
Sbjct: 294 HQEVRSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEW---LQLPSYERPHFY 350

Query: 203 FLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTD 262
            L+L   D++GH + P+S + I  ++ VD  +  +   +     D     +  SDHGM  
Sbjct: 351 TLYLEEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKDLGLDKCLNLILISDHGMEQ 410

Query: 263 WGS 265
              
Sbjct: 411 GSC 413
>gb|AAL26912.1| (AF320054) ecto-nucleotide pyrophosphatase [Rattus norvegicus]
          Length = 906

 Score =  255 bits (647), Expect = 2e-66
 Identities = 42/243 (17%), Positives = 83/243 (33%), Gaps = 18/243 (7%)

Query: 35  PQFINSQEAPA----KRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHI- 89
            + I++ + PA        + S DG R +  + +    P +  + N              
Sbjct: 177 CETIDAPQCPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGT---YTKNMRPV 233

Query: 90  -PTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSV----FNRSSYSWMWGSPDIVNLF 144
            PT++ P H +I  G+  +   +      +P    S       + +  W  G P  V   
Sbjct: 234 YPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTAN 293

Query: 145 DDLPNAESFSYSADEEDFAS--KDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIF 202
                + ++ +   + +      D   +        E  L   +    L     E+   +
Sbjct: 294 HQEVRSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEW---LQLPSYERPHFY 350

Query: 203 FLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTD 262
            L+L   D++GH + P+S + I  ++ VD  +  +   +     D     +  SDHGM  
Sbjct: 351 TLYLEEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKDLGLDKCLNLILISDHGMEQ 410

Query: 263 WGS 265
              
Sbjct: 411 GSC 413
>dbj|BAA02053.1| (D12485) The first in-frame ATG codon is located at nucleotides
           17-19, followed by a second ATG codon 52 codons
           downstream. And the second ATG codon is potential
           initiation point for translation of NPPase. [Homo
           sapiens]
          Length = 930

 Score =  255 bits (646), Expect = 3e-66
 Identities = 43/244 (17%), Positives = 80/244 (32%), Gaps = 18/244 (7%)

Query: 34  PPQFINSQEAPA----KRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHI 89
           P + IN  + PA        + S DG R +  + +    P +  +               
Sbjct: 199 PCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGT---YTKNMRP 255

Query: 90  --PTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSV----FNRSSYSWMWGSPDIVNL 143
             PT++ P H +I  G+  +   +      +P    S       + +  W  G P  V  
Sbjct: 256 VYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTA 315

Query: 144 FDDLPNAESFSYSADEEDFAS--KDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSI 201
                 + +F +   + +      D   +        E  L   +    L     E+   
Sbjct: 316 KYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQW---LQLPKDERPHF 372

Query: 202 FFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMT 261
           + L+L   D++GH   P+S + I  ++ VD  +  +   +           +  SDHGM 
Sbjct: 373 YTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGME 432

Query: 262 DWGS 265
               
Sbjct: 433 QGSC 436
>gb|AAK69653.1|AF340185_1 (AF340185) ecto-nucleotide pyrophosphatase/phosphodiesterase-1
           [Rattus norvegicus]
          Length = 906

 Score =  254 bits (645), Expect = 3e-66
 Identities = 42/243 (17%), Positives = 83/243 (33%), Gaps = 18/243 (7%)

Query: 35  PQFINSQEAPA----KRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHI- 89
            + I++ + PA        + S DG R +  + +    P +  + N              
Sbjct: 177 CETIDAPQCPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGT---YTKNMRPV 233

Query: 90  -PTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSV----FNRSSYSWMWGSPDIVNLF 144
            PT++ P H +I  G+  +   +      +P    S       + +  W  G P  V   
Sbjct: 234 YPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTAN 293

Query: 145 DDLPNAESFSYSADEEDFAS--KDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIF 202
                + ++ +   + +      D   +        E  L   +    L     E+   +
Sbjct: 294 HQEVRSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEW---LQLPSYERPHFY 350

Query: 203 FLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTD 262
            L+L   D++GH + P+S + I  ++ VD  +  +   +     D     +  SDHGM  
Sbjct: 351 TLYLEEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKDLGLDKCLNLILISDHGMEQ 410

Query: 263 WGS 265
              
Sbjct: 411 GSC 413
>pir||A39216 plasma cell membrane glycoprotein PC-1 - human
 gb|AAF36094.1| (AF110304) PDNP1 [Homo sapiens]
 emb|CAC39442.1| (AJ242020) plasma cell membrane glycoprotein [Homo sapiens]
          Length = 925

 Score =  254 bits (645), Expect = 3e-66
 Identities = 43/244 (17%), Positives = 80/244 (32%), Gaps = 18/244 (7%)

Query: 34  PPQFINSQEAPA----KRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHI 89
           P + IN  + PA        + S DG R +  + +    P +  +               
Sbjct: 194 PCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGT---YTKNMRP 250

Query: 90  --PTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSV----FNRSSYSWMWGSPDIVNL 143
             PT++ P H +I  G+  +   +      +P    S       + +  W  G P  V  
Sbjct: 251 VYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTA 310

Query: 144 FDDLPNAESFSYSADEEDFAS--KDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSI 201
                 + +F +   + +      D   +        E  L   +    L     E+   
Sbjct: 311 KYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQW---LQLPKDERPHF 367

Query: 202 FFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMT 261
           + L+L   D++GH   P+S + I  ++ VD  +  +   +           +  SDHGM 
Sbjct: 368 YTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGME 427

Query: 262 DWGS 265
               
Sbjct: 428 QGSC 431
>ref|NP_006199.1| (NM_006208) ectonucleotide pyrophosphatase/phosphodiesterase 1;
           phosphodiesterase I/nucleotide pyrophosphatase 1
           (homologous to mouse Ly-41 antigen); plasma-cell
           membrane glycoprotein [Homo sapiens]
 sp|P22413|PC1_HUMAN ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (PLASMA-CELL
           MEMBRANE GLYCOPROTEIN PC-1) [INCLUDES: ALKALINE
           PHOSPHODIESTERASE I ; NUCLEOTIDE PYROPHOSPHATASE
           (NPPASE)]
 gb|AAA63237.1| (M57736) plasma cell membrane glycoprotein PC-1 [Homo sapiens]
 dbj|BAA02054.1| (D12485) NPPase [Homo sapiens]
          Length = 873

 Score =  252 bits (639), Expect = 2e-65
 Identities = 43/244 (17%), Positives = 80/244 (32%), Gaps = 18/244 (7%)

Query: 34  PPQFINSQEAPA----KRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHI 89
           P + IN  + PA        + S DG R +  + +    P +  +               
Sbjct: 142 PCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGT---YTKNMRP 198

Query: 90  --PTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSV----FNRSSYSWMWGSPDIVNL 143
             PT++ P H +I  G+  +   +      +P    S       + +  W  G P  V  
Sbjct: 199 VYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTA 258

Query: 144 FDDLPNAESFSYSADEEDFAS--KDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSI 201
                 + +F +   + +      D   +        E  L   +    L     E+   
Sbjct: 259 KYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQW---LQLPKDERPHF 315

Query: 202 FFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMT 261
           + L+L   D++GH   P+S + I  ++ VD  +  +   +           +  SDHGM 
Sbjct: 316 YTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGME 375

Query: 262 DWGS 265
               
Sbjct: 376 QGSC 379
>emb|CAB99365.1| (AL117378) dJ131F15.2 (phosphodiesterase I/nucleotide
           pyrophosphatase 1 (homologous to mouse Ly-41 antigen)
           (PC1, NPPS)) [Homo sapiens]
          Length = 845

 Score =  251 bits (637), Expect = 3e-65
 Identities = 43/244 (17%), Positives = 80/244 (32%), Gaps = 18/244 (7%)

Query: 34  PPQFINSQEAPA----KRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHI 89
           P + IN  + PA        + S DG R +  + +    P +  +               
Sbjct: 114 PCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGT---YTKNMRP 170

Query: 90  --PTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSV----FNRSSYSWMWGSPDIVNL 143
             PT++ P H +I  G+  +   +      +P    S       + +  W  G P  V  
Sbjct: 171 VYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTA 230

Query: 144 FDDLPNAESFSYSADEEDFAS--KDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSI 201
                 + +F +   + +      D   +        E  L   +    L     E+   
Sbjct: 231 KYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQW---LQLPKDERPHF 287

Query: 202 FFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMT 261
           + L+L   D++GH   P+S + I  ++ VD  +  +   +           +  SDHGM 
Sbjct: 288 YTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGME 347

Query: 262 DWGS 265
               
Sbjct: 348 QGSC 351
>gb|AAH03264.1|AAH03264 (BC003264) ectonucleotide pyrophosphatase/phosphodiesterase 2 [Mus
           musculus]
          Length = 862

 Score =  238 bits (603), Expect = 3e-61
 Identities = 48/277 (17%), Positives = 91/277 (32%), Gaps = 46/277 (16%)

Query: 34  PPQFINSQEAPA----KRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHI 89
             + I   E PA      + I S DG R     K     P +  + +       + R   
Sbjct: 147 DCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYM-RPVY 205

Query: 90  PTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSVFN-----RSSYSWMWGSPDIVNLF 144
           PT++ P    +  G+  +   +      +PV FD+ F+     + ++ W  G P  +   
Sbjct: 206 PTKTFPNLYTLATGLYPESHGIVGNSMYDPV-FDATFHLRGREKFNHRWWGGQPLWITAT 264

Query: 145 DDLPNAESFSYSADEEDFASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFL 204
                A +F +S                    H    L   +    L+    E+ S++  
Sbjct: 265 KQGVRAGTFFWSVSIP----------------HERRILTILQW---LSLPDNERPSVYAF 305

Query: 205 HLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWG 264
           +    D +GH   P   +  + ++ +D  + ++   +           +F  DHGM D  
Sbjct: 306 YSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVT 365

Query: 265 SHGAGSDDEVLTPFVAWGAGVKQGGPKLDLNQIDLAP 301
                      T F++            +++ I L P
Sbjct: 366 CD--------RTEFLSNY--------LTNVDDITLVP 386
 Score = 35.3 bits (81), Expect = 4.3
 Identities = 13/53 (24%), Positives = 22/53 (40%), Gaps = 1/53 (1%)

Query: 264 GSHGAGSD-DEVLTPFVAWGAGVKQGGPKLDLNQIDLAPLISALIGCPIPVNS 315
           G HG  +  + + T FV +G   K          I+L  ++  L+G     N+
Sbjct: 472 GDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNN 524
>gb|AAF56711.1| (AE003761) CG13978 gene product [Drosophila melanogaster]
          Length = 475

 Score =  238 bits (602), Expect = 4e-61
 Identities = 70/220 (31%), Positives = 101/220 (45%), Gaps = 10/220 (4%)

Query: 3   WKFLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFIN---SQEAPAKRIFIISADGLRYD 59
           WK    ++ VH++L+ +I + Y+   L+  + PQ        E PA R+ +   DGLR  
Sbjct: 2   WKL--QALVVHILLMGAILNTYFQHTLLPNLVPQKTMRELGLEPPADRLVVFVTDGLRAA 59

Query: 60  TFNKYP-DKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKN 118
           TF        P L  I  + +G  G+SR+  PT +RPGH+AIFAG  ED +A       N
Sbjct: 60  TFLANNGSDVPDLKDIYRQ-QGRIGISRTCAPTMTRPGHIAIFAGFHEDPAASLMHLCYN 118

Query: 119 PVQFDSVFNRSSYSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASNLDKWVFEHF 178
           P  FD+VFNRS     W    IV  F  L +  +        +    +    DKW F+  
Sbjct: 119 PGDFDTVFNRSRNMIGWAHSYIVGYFVKLSHGGAPLRFDSYMERDLPEKLTCDKWAFDKV 178

Query: 179 ENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKP 218
           ENFL               + ++FF++L  +D   H  KP
Sbjct: 179 ENFLRNVDNVREWR---NYKPAVFFVYLADMDIAAHRFKP 215
 Score =  235 bits (596), Expect = 2e-60
 Identities = 62/253 (24%), Positives = 108/253 (42%), Gaps = 19/253 (7%)

Query: 265 SHGAGSDDEVLTPFVAWGAGVK---------QGGPKL--DLNQIDLAPLISALIGCPIPV 313
           +HG+GS  EV TP   WGAGVK                  ++Q  LAPL+S+LIG P P 
Sbjct: 218 AHGSGSPLEVETPLFMWGAGVKRDEIDAEANFPEKPNISQVDQTQLAPLMSSLIGLPPPK 277

Query: 314 NSMGILPVQMMNSKGSSYEFKAIEANFKQLKEQIIFLKNAKSRRLWFRQFEKFGDKAMES 373
           N++ ++PV  +N     Y+  A+  N  QL  Q   L     + ++++   KF +  +  
Sbjct: 278 NNLALMPVGYLNV-SDEYQAVALHLNVLQLLSQAEILIGRHEKAIFYKWLPKFKELHIGV 336

Query: 374 LRTTLAQ---LGRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIAL 430
           +    AQ   L  +   + A     +   L K+ + +Y++Y +  L  A S S++ W   
Sbjct: 337 IDQYAAQFDILKSEGNLTDAMEFCKEYGKLAKKCLTYYNQYYQTPLIVANSMSYMIWFYC 396

Query: 431 VVSFLHNSTSKENLSLLVPHHLFIIPLACSLLFTA----YCSLSMTQTIYIILPIYLISI 486
           ++  L   + KE +       +  + LA   +          +      Y+ILP+ ++ +
Sbjct: 397 LLLQLTRLSKKEKMQRRGFMTVSTLILAMIGILLIAMMELQKVPHIAAFYLILPVGMLIM 456

Query: 487 LENHSKLTQRIRE 499
            +        I E
Sbjct: 457 AQAERPDIDMIPE 469
>dbj|BAA08260.1| (D45421) phosphodiesterase I alpha [Homo sapiens]
          Length = 863

 Score =  236 bits (598), Expect = 1e-60
 Identities = 49/277 (17%), Positives = 92/277 (32%), Gaps = 46/277 (16%)

Query: 34  PPQFINSQEAPA----KRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHI 89
             + I + E PA      + I S DG R     K     P +  + +       + R   
Sbjct: 148 DCEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYM-RPVY 206

Query: 90  PTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSVFN-----RSSYSWMWGSPDIVNLF 144
           PT++ P    +  G+  +   +      +PV FD+ F+     + ++ W  G P  +   
Sbjct: 207 PTKTFPNLYTLATGLYPESHGIVGNSMYDPV-FDATFHLRGREKFNHRWWGGQPLWITAT 265

Query: 145 DDLPNAESFSYSADEEDFASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFL 204
                A +F +S                 V  H    L   +    L     E+ S++  
Sbjct: 266 KQGVKAGTFFWSV----------------VIPHERRILTILQW---LTLPDHERPSVYAF 306

Query: 205 HLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWG 264
           +    D +GH   P   +  + ++ +D  + ++   +           +F  DHGM D  
Sbjct: 307 YSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVT 366

Query: 265 SHGAGSDDEVLTPFVAWGAGVKQGGPKLDLNQIDLAP 301
                      T F++            +++ I L P
Sbjct: 367 CD--------RTEFLSNY--------LTNVDDITLVP 387
 Score = 36.5 bits (84), Expect = 2.1
 Identities = 13/53 (24%), Positives = 22/53 (40%), Gaps = 1/53 (1%)

Query: 264 GSHGAGSD-DEVLTPFVAWGAGVKQGGPKLDLNQIDLAPLISALIGCPIPVNS 315
           G HG  +  + + T FV +G   K          I+L  ++  L+G     N+
Sbjct: 473 GDHGFDNKVNSMQTVFVGYGPTFKYKTKVPPFENIELYNVMCDLLGLKPAPNN 525
>ref|NP_006200.1| (NM_006209) ectonucleotide pyrophosphatase/phosphodiesterase 2
           (autotaxin); Phosphodiesterase I/nucleotide
           pyrophosphatase 2; autotaxin; phosphodiesterase
           I/nucleotide pyrophosphatase 2 (autotaxin) [Homo
           sapiens]
 gb|AAB00855.1| (L46720) autotaxin-t [Homo sapiens]
          Length = 863

 Score =  236 bits (598), Expect = 1e-60
 Identities = 49/277 (17%), Positives = 92/277 (32%), Gaps = 46/277 (16%)

Query: 34  PPQFINSQEAPA----KRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHI 89
             + I + E PA      + I S DG R     K     P +  + +       + R   
Sbjct: 148 DCEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYM-RPVY 206

Query: 90  PTESRPGHVAIFAGITEDISAVAKGWKKNPVQFDSVFN-----RSSYSWMWGSPDIVNLF 144
           PT++ P    +  G+  +   +      +PV FD+ F+     + ++ W  G P  +   
Sbjct: 207 PTKTFPNLYTLATGLYPESHGIVGNSMYDPV-FDATFHLRGREKFNHRWWGGQPLWITAT 265

Query: 145 DDLPNAESFSYSADEEDFASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFL 204
                A +F +S                 V  H    L   +    L     E+ S++  
Sbjct: 266 KQGVKAGTFFWSV----------------VIPHERRILTILQW---LTLPDHERPSVYAF 306

Query: 205 HLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWG 264
           +    D +GH   P   +  + ++ +D  + ++   +           +F  DHGM D  
Sbjct: 307 YSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVT 366

Query: 265 SHGAGSDDEVLTPFVAWGAGVKQGGPKLDLNQIDLAP 301
                      T F++            +++ I L P
Sbjct: 367 CD--------RTEFLSNY--------LTNVDDITLVP 387
 Score = 36.5 bits (84), Expect = 2.2
 Identities = 13/53 (24%), Positives = 22/53 (40%), Gaps = 1/53 (1%)

Query: 264 GSHGAGSD-DEVLTPFVAWGAGVKQGGPKLDLNQIDLAPLISALIGCPIPVNS 315
           G HG  +  + + T FV +G   K          I+L  ++  L+G     N+
Sbjct: 473 GDHGFDNKVNSMQTVFVGYGPTFKYKTKVPPFENIELYNVMCDLLGLKPAPNN 525
>ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thaliana]
 dbj|BAB10512.1| (AB005238) gene_id:MKP11.10~unknown protein [Arabidopsis thaliana]
          Length = 884

 Score =  232 bits (588), Expect = 2e-59
 Identities = 54/319 (16%), Positives = 92/319 (27%), Gaps = 62/319 (19%)

Query: 4   KFLIAS-ITVH-LVLIYSIFDVYYT---------------SPLVHGIPPQFINSQE--AP 44
           K      + +H + ++        T               SP +        +S E    
Sbjct: 9   KLTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSPCLASPRSNHDSSSEPKPW 68

Query: 45  AKRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGI 104
             ++ I+        T     D                  + +  PT S      +  G 
Sbjct: 69  MDKLTIL-------QTLAFANDS-----------SAKIFKAFADPPTTSLQRLKGLTTGG 110

Query: 105 TEDISAVAKGWKKNPVQFDSVFNR----SSYSWMWGSPDIVNLFDDLPNAESFSYSADEE 160
                 +   +    +  D+  N+         M G      LF        F  S    
Sbjct: 111 LPTFIDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFP-----NQFQKSYPFP 165

Query: 161 DFASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMS 220
            F  KD   +D    EH    L             ++   +   H LG+D  GH     S
Sbjct: 166 SFNVKDLDTVDNGCIEHLFPTL------------FKDDWDVLIAHFLGVDHAGHIFGVDS 213

Query: 221 RQYIDNIKVVDSGIEKVQHLVDAF----FGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLT 276
              I+ ++  +S +EKV +++++          T  +   DHG T  G HG G+ +EV T
Sbjct: 214 SPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVET 273

Query: 277 PFVAWGAGVKQGGPKLDLN 295
              A            + +
Sbjct: 274 TMFAMSTKKHTTLVPPEFD 292
>ref|NP_476445.1| (NM_057104) phosphodiesterase I/nucleotide pyrophosphatase 2;
           phosphodiesterase I/nucleotide pyrophosphatase 2
           (autotaxin) [Rattus norvegicus]
 pir||A55453 plasma cell membrane glycoprotein PC-1, brain specific - rat
 dbj|BAA05910.1| (D28560) phosphodiesterase I [Rattus norvegicus]
          Length = 885

 Score =  228 bits (577), Expect = 3e-58
 Identities = 45/264 (17%), Positives = 87/264 (32%), Gaps = 43/264 (16%)

Query: 43  APAKRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFA 102
            P   + I S DG R     K     P +  + +    +    R   PT++ P    +  
Sbjct: 159 CP-PPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHVPYT-RPVYPTKTFPNLYTLAT 216

Query: 103 GITEDISAVAKGWKKNPVQFDSVFN-----RSSYSWMWGSPDIVNLFDDLPNAESFSYSA 157
           G+  +   +      +PV FD+ F+     + ++ W  G P  +        A +F +S 
Sbjct: 217 GLYPESHGIVGNSMYDPV-FDASFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSV 275

Query: 158 DEEDFASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNK 217
                              H    L   +    L+    E+ S++  +    D +GH   
Sbjct: 276 SIP----------------HERRILTILQW---LSLPDNERPSVYAFYSEQPDFSGHKYG 316

Query: 218 PMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTP 277
           P   +  + ++ +D  + ++   +           +F  DHGM D             T 
Sbjct: 317 PFGPEMTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHGMEDVTCD--------RTE 368

Query: 278 FVAWGAGVKQGGPKLDLNQIDLAP 301
           F++            +++ I L P
Sbjct: 369 FLSNY--------LTNVDDITLVP 384
 Score = 35.7 bits (82), Expect = 3.9
 Identities = 13/53 (24%), Positives = 22/53 (40%), Gaps = 1/53 (1%)

Query: 264 GSHGAGSD-DEVLTPFVAWGAGVKQGGPKLDLNQIDLAPLISALIGCPIPVNS 315
           G HG  +  + + T FV +G   K          I+L  ++  L+G     N+
Sbjct: 470 GDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNN 522
>ref|NP_281901.1| (NC_002163) hypothetical protein Cj0729 [Campylobacter jejuni]
 pir||D81344 hypothetical protein Cj0729 [imported] - Campylobacter jejuni
           (strain NCTC 11168)
 emb|CAB73003.1| (AL139076) hypothetical protein Cj0729 [Campylobacter jejuni]
          Length = 269

 Score =  219 bits (554), Expect = 1e-55
 Identities = 55/274 (20%), Positives = 112/274 (40%), Gaps = 30/274 (10%)

Query: 45  AKRIFIISADGLRYDTFNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGI 104
             +  ++  DGL   +         YL+++  E  G +      +P+ SRP +  +  G+
Sbjct: 2   MSKAILVVLDGLNCKSA---SINMGYLNALCKENLGKFYSLECELPSMSRPLYECLLTGV 58

Query: 105 TEDISAVAKG---WKKNPVQFDSVFNR------SSYSWMWGSPDIVNLFDDLPNAESFSY 155
              +S +      + K    FD    +      ++Y W++   ++ N  + +P+      
Sbjct: 59  KPVLSGIINNKLSFSKQTSIFDLCKEQGLKAGGAAYHWVF---ELYNKKEFIPS---LHR 112

Query: 156 SADEEDFASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHG 215
             ++E+        L    F + +++L++    +  + + +       +H + ID  GH 
Sbjct: 113 HIEDENL------TLPYGHFYYEDDYLDSHLFADGEHLRNKYNLDFTLIHSMNIDDAGHK 166

Query: 216 NKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVL 275
               S +Y +  K VD     +       + +     + TSDHGMT+  SHG  S+DE+L
Sbjct: 167 FGSHSIEYANKTKKVD----ILISEYLPTWLEQGINVIITSDHGMTEGKSHGGLSEDEIL 222

Query: 276 TPFVAWGAGVKQGGPKLDLNQIDLAPLISALIGC 309
            PF  +G+       K+  ++I     I  ++G 
Sbjct: 223 VPFFTFGSAFSYENAKIKQDEI--CGSICEILGL 254
>dbj|BAB17014.1| (AB050262) hypothetical protein [Macaca fascicularis]
          Length = 333

 Score =  216 bits (546), Expect = 1e-54
 Identities = 58/284 (20%), Positives = 102/284 (35%), Gaps = 30/284 (10%)

Query: 201 IFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKT--AWLFTSDH 258
           +  LH LG+D  GH + P S      +  +DS + K+   + +   +       +   DH
Sbjct: 1   MLILHYLGLDHIGHISGPNSPLIGHKLSEMDSVLMKIHTSLQSKERETPLPNLLVLCGDH 60

Query: 259 GMTDWGSHGAGSDDEVLTPFVAWGAGVKQG-----GPKLDLNQIDLAPLISALIGCPIPV 313
           GM++ GSHGA S +EV TP +   +  ++       PK  + Q D+A  ++  +G PIP 
Sbjct: 61  GMSETGSHGASSMEEVNTPLILISSAFERKPGDIRHPKH-VQQTDVAATLAIALGLPIPK 119

Query: 314 NSMGILPVQMMNSKGSSYEFKAIEANFKQLKEQIIFLKNAKSRRLWFRQFEKFGDKAM-- 371
           +S+G L   ++  +    + + +  N  QL      L+           +EK        
Sbjct: 120 DSVGSLLFPVVEGRPMREQLRFLHLNTVQLS---KLLQENVPS------YEKDPGFEQFK 170

Query: 372 --ESLRTTLAQLGRDRRFSVAT---------SLFADNAHLMKEAIVFYHRYDRQMLGAAV 420
             E L     +L  + + S               A    L         +YD   +    
Sbjct: 171 MSERLHGNWIRLYLEEKHSEVLFNLGSKVLRQYLAALKTLSLSLSTQVAQYDMYSMMVGT 230

Query: 421 SCSFVAWIALVVSFLHNSTSKENLSLLVPHHLFIIPLACSLLFT 464
                    L++S       K  L + +    F +     +L  
Sbjct: 231 VVVLEVLTLLLLSVPQALHRKAELEVPLSSPEFSLLFYLVILVL 274
CPU time:   285.78 user secs.	    3.33 sys. secs	  289.11 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.316    0.177    0.477 

Gapped
Lambda     K      H
   0.270   0.0621    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 650621092
Number of Sequences: 887402
Number of extensions: 37927257
Number of successful extensions: 179520
Number of sequences better than 10.0: 1564
Number of HSP's better than 10.0 without gapping: 156
Number of HSP's successfully gapped in prelim test: 1449
Number of HSP's that attempted gapping in prelim test: 176124
Number of HSP's gapped (non-prelim): 3792
length of query: 929
length of database: 277,845,442
effective HSP length: 56
effective length of query: 873
effective length of database: 228,150,930
effective search space: 199175761890
effective search space used: 199175761890
T: 11
A: 40
X1: 15 ( 6.8 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.7 bits)
S2: 78 (34.4 bits)