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GPI Anchor Biosynthesis Report: NP_179839.1 (GPI7 family, Arabidopsis thaliana)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 
         (897 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Results of PSI-Blast iteration 5

Distribution of 64 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)
Sequences producing significant alignments: (bits) Value
ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thalia... 930 0.0
ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class ... 758 0.0
ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class ... 731 0.0
dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N sh... 706 0.0
gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinosito... 701 0.0
pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragme... 627 e-178
gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caeno... 614 e-174
pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast (... 608 e-172
gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melano... 597 e-169
pir||T40715 hypothetical protein SPBC839.08c - fission yeast (S... 588 e-167
ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; ... 576 e-163
gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melano... 518 e-145
ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class ... 479 e-134
pir||T02245 hypothetical protein P1.11659_3 - human >gi|2984587|... 447 e-124
ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan... 440 e-122
gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melan... 434 e-120
ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) ... 428 e-118
dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [M... 417 e-115
ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans] 361 3e-98
gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarr... 355 3e-96
dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:13516... 338 3e-91
gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melano... 327 7e-88
sp|Q09782|YA93_SCHPO HYPOTHETICAL 85.7 KD PROTEIN C13G6.03 IN CH... 325 2e-87
ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involv... 319 1e-85
gb|AAL39196.1| (AY069051) GH05767p [Drosophila melanogaster] 292 2e-77
ref|NP_495820.1| (NM_063419) Yeast YJ10 like [Caenorhabditis ele... 292 2e-77
ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thalia... 280 7e-74
dbj|BAB17014.1| (AB050262) hypothetical protein [Macaca fascicul... 255 2e-66
ref|NP_491098.1| (NM_058697) M01B12.2.p [Caenorhabditis elegans]... 254 5e-66
dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like prote... 246 9e-64
ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like p... 243 7e-63
dbj|BAB55130.1| (AK027465) unnamed protein product [Homo sapiens] 239 1e-61
ref|NP_060203.1| (NM_017733) hypothetical protein FLJ20265 [Homo... 239 2e-61
ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like pr... 239 2e-61
gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophos... 237 8e-61
ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo ... 234 5e-60
ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like p... 230 1e-58
ref|NP_116023.1| (NM_032634) hypothetical protein MGC3079 [Homo ... 225 4e-57
pir||T03293 nucleotide pyrophosphatase homolog - rice >gi|818849... 219 2e-55
ref|NP_281901.1| (NC_002163) hypothetical protein Cj0729 [Campyl... 211 5e-53
ref|NP_105837.1| (NC_002678) hypothetical protein [Mesorhizobium... 205 2e-51
ref|NP_114392.1| (NM_032003) ectonucleotide pyrophosphatase/phos... 195 4e-48
gb|AAH11294.1|AAH11294 (BC011294) ectonucleotide pyrophosphatase... 195 4e-48
dbj|BAA87261.1| (AB027957) Hypothetical protein [Schizosaccharom... 191 3e-47
pir||T40657 probable phophodiesterase-nucleotide pyrophosp hatas... 190 9e-47
ref|NP_251941.1| (NC_002516) hypothetical protein [Pseudomonas a... 190 9e-47
ref|NP_067547.1| (NM_021572) ectonucleotide pyrophosphatase/phos... 189 1e-46
ref|NP_299876.1| (NC_002488) phosphodiesterase-nucleotide pyroph... 183 1e-44
ref|NP_038993.1| (NC_002188) ORF FPV030 Alkaline phosphodiestera... 179 2e-43
Alignments
>ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thaliana]
 gb|AAF18652.1| (AC006592) unknown protein [Arabidopsis thaliana]
          Length = 897

 Score =  930 bits (2380), Expect = 0.0
 Identities = 897/897 (100%), Positives = 897/897 (100%)

Query: 1   MTTAAMTCTRLTIFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLIS 60
           MTTAAMTCTRLTIFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLIS
Sbjct: 1   MTTAAMTCTRLTIFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLIS 60

Query: 61  NESELHHPEKLRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAK 120
           NESELHHPEKLRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAK
Sbjct: 61  NESELHHPEKLRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAK 120

Query: 121 AAPPTVTMPRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLK 180
           AAPPTVTMPRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLK
Sbjct: 121 AAPPTVTMPRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLK 180

Query: 181 LFPGLFMRHDGVSSFFVKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVGHTGGRN 240
           LFPGLFMRHDGVSSFFVKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVGHTGGRN
Sbjct: 181 LFPGLFMRHDGVSSFFVKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVGHTGGRN 240

Query: 241 SPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSL 300
           SPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSL
Sbjct: 241 SPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSL 300

Query: 301 MLFIGLNSNISDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRDFEQL 360
           MLFIGLNSNISDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRDFEQL
Sbjct: 301 MLFIGLNSNISDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRDFEQL 360

Query: 361 RALELNSWQLLRLMLAQIQSSSFPRVSCNCFLDGTCEGLDLDISECSGDKEKQLICLFRN 420
           RALELNSWQLLRLMLAQIQSSSFPRVSCNCFLDGTCEGLDLDISECSGDKEKQLICLFRN
Sbjct: 361 RALELNSWQLLRLMLAQIQSSSFPRVSCNCFLDGTCEGLDLDISECSGDKEKQLICLFRN 420

Query: 421 AAALHGIWKSKKSTESSSTMEDFSRALDAYNTFLKTASEWLASKTTEKPVLLLGLGVSAM 480
           AAALHGIWKSKKSTESSSTMEDFSRALDAYNTFLKTASEWLASKTTEKPVLLLGLGVSAM
Sbjct: 421 AAALHGIWKSKKSTESSSTMEDFSRALDAYNTFLKTASEWLASKTTEKPVLLLGLGVSAM 480

Query: 481 LLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFIFALLLILVISMGSSSMVEEE 540
           LLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFIFALLLILVISMGSSSMVEEE
Sbjct: 481 LLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFIFALLLILVISMGSSSMVEEE 540

Query: 541 HYIWHFMVSTFHLLLLFKTAKSFKISKGMNILRDFKFGSIFSLLISGRLLRGWHQGGVNW 600
           HYIWHFMVSTFHLLLLFKTAKSFKISKGMNILRDFKFGSIFSLLISGRLLRGWHQGGVNW
Sbjct: 541 HYIWHFMVSTFHLLLLFKTAKSFKISKGMNILRDFKFGSIFSLLISGRLLRGWHQGGVNW 600

Query: 601 TYLPDISKWLVQGGSGYVKWIQLISIILVIGLGLYTLFRTGSNRKGVRILAFGFSTCGFL 660
           TYLPDISKWLVQGGSGYVKWIQLISIILVIGLGLYTLFRTGSNRKGVRILAFGFSTCGFL
Sbjct: 601 TYLPDISKWLVQGGSGYVKWIQLISIILVIGLGLYTLFRTGSNRKGVRILAFGFSTCGFL 660

Query: 661 VLLHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVLPWSALNKDKSFLAEVGDCLY 720
           VLLHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVLPWSALNKDKSFLAEVGDCLY
Sbjct: 661 VLLHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVLPWSALNKDKSFLAEVGDCLY 720

Query: 721 LIGSAYILCWCLLQQLLQQPINSGPILLLLLQILAILCLSSSDFQVNEWVEITALYYMGM 780
           LIGSAYILCWCLLQQLLQQPINSGPILLLLLQILAILCLSSSDFQVNEWVEITALYYMGM
Sbjct: 721 LIGSAYILCWCLLQQLLQQPINSGPILLLLLQILAILCLSSSDFQVNEWVEITALYYMGM 780

Query: 781 AGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMFMITYASPMLFLLSLVMYIGANLR 840
           AGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMFMITYASPMLFLLSLVMYIGANLR
Sbjct: 781 AGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMFMITYASPMLFLLSLVMYIGANLR 840

Query: 841 NHSNSTISTHRETTKARVPLPCSALHQLNTLDRIYCGLTTHEKSPLCMERLLSQVSL 897
           NHSNSTISTHRETTKARVPLPCSALHQLNTLDRIYCGLTTHEKSPLCMERLLSQVSL
Sbjct: 841 NHSNSTISTHRETTKARVPLPCSALHQLNTLDRIYCGLTTHEKSPLCMERLLSQVSL 897
>ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class N [Mus musculus]
 dbj|BAA82619.1| (AB030279) phosphatidylinositolglycan class N [Mus musculus]
          Length = 931

 Score =  758 bits (1938), Expect = 0.0
 Identities = 144/882 (16%), Positives = 285/882 (31%), Gaps = 129/882 (14%)

Query: 13  IFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLR 72
           +F   G+L+  +     +F  +   P + G++                  + L  P K R
Sbjct: 3   LFFALGLLIHFVFFV-SIFDIYFTSPLVHGMTPQ---------------FTPLPPPAK-R 45

Query: 73  LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLK 132
           L+  V DGL A+ +   D            P+ ++++ + +     +    PT + P   
Sbjct: 46  LVLFVADGLRADTLYELDEDGN-----SRAPFIRNVIMH-EGSWGVSHTRVPTESRPGHV 99

Query: 133 AMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFM----R 188
           A+++G       VA  +    +  D++  +           G    L +F          
Sbjct: 100 ALIAGFYEDVSAVAKGWKENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVY 155

Query: 189 HDGVSS----FFVKDTVQVDRNVSRHLPDELN------------SDDWNLLILHYLGLDH 232
                +    F   D  ++D  V   + D  +            +++  +  LH LG+D 
Sbjct: 156 TYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDT 215

Query: 233 VGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGS 292
            GH    +S      +K++DD V+ +          D G+T  I  SDHGMT+ G+HG  
Sbjct: 216 NGHAHRPSSREYKDNIKKVDDGVKEIV-SIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAG 274

Query: 293 SYEETDSLMLFIGLNSNISDYASAT----------------NNVAFQVDLAPTLALLFGV 336
              ET +  +  G         SA                      Q D+AP +A L GV
Sbjct: 275 HPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGV 334

Query: 337 PIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLRL---MLAQIQSSSFPRVSCNCFLD 393
           P P N+VG+L  G L +     +  ++  N+ Q+L      + Q + ++ P +     L 
Sbjct: 335 PFPLNSVGILPVGYLNNTG-LFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLL 393

Query: 394 GTCEGLDLDISECSGDKEKQLICLFRNAAALHGI-WKSKKSTESSSTMEDFSRALDAYNT 452
              + LD+     S  K+++   +      L  +  +      +   +         +  
Sbjct: 394 SDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVG 453

Query: 453 FLKTASEWLASKTTE--KPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRV---- 506
           ++   S  +    +   K     G     +LL  FI   V ++ F  +   P        
Sbjct: 454 WMSYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCL 513

Query: 507 CSLSNLLNLEEVFIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHL-LLLFKTAKSFKI 565
             +     +         L+  +     S     H++ + +V T  + +L+      + +
Sbjct: 514 LPVPIWYAVLREHEVIQDLVESLLTFPRS-----HFVAYLLVFTLGIEVLVLSFFYRYML 568

Query: 566 SKGMNILRDFKF-GSIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLI 624
           + G+ +   + F   ++                   T+L     W        V  +  +
Sbjct: 569 TAGLIVFAGWPFLTQLW--------------TRAKITFLS----WAFFSLLLAVFPLMPV 610

Query: 625 S-----IILVIGLGLY-----------------TLFRTGSNRKGVRILAFGFSTCGFLVL 662
                 + LV+G G                    L +       +++L+   S       
Sbjct: 611 VGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYST 670

Query: 663 LHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVLPWSALNKDKSFLAEVGDCLYLI 722
            H    ++ L           +   L++      +L    +++         +    Y  
Sbjct: 671 HHSLLKKEGLPLMNQIVSWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEA 730

Query: 723 GSAYILCWCLL------QQLLQQPINSGPILLLLLQIL-AILCLSSSDFQVNEWVEITAL 775
               +L   +       Q+ LQQP  S    L  +Q               ++      L
Sbjct: 731 LFPLVLSCLMFVWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFL 790

Query: 776 YYMGMAGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMF 817
            +  +   F  GN  ++ + D+A  +  ++  S  + G LM 
Sbjct: 791 VFFLLTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMM 832
 Score =  758 bits (1938), Expect = 0.0
 Identities = 144/882 (16%), Positives = 285/882 (31%), Gaps = 129/882 (14%)

Query: 13  IFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLR 72
           +F   G+L+  +     +F  +   P + G++                  + L  P K R
Sbjct: 3   LFFALGLLIHFVFFV-SIFDIYFTSPLVHGMTPQ---------------FTPLPPPAK-R 45

Query: 73  LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLK 132
           L+  V DGL A+ +   D            P+ ++++ + +     +    PT + P   
Sbjct: 46  LVLFVADGLRADTLYELDEDGN-----SRAPFIRNVIMH-EGSWGVSHTRVPTESRPGHV 99

Query: 133 AMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFM----R 188
           A+++G       VA  +    +  D++  +           G    L +F          
Sbjct: 100 ALIAGFYEDVSAVAKGWKENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVY 155

Query: 189 HDGVSS----FFVKDTVQVDRNVSRHLPDELN------------SDDWNLLILHYLGLDH 232
                +    F   D  ++D  V   + D  +            +++  +  LH LG+D 
Sbjct: 156 TYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDT 215

Query: 233 VGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGS 292
            GH    +S      +K++DD V+ +          D G+T  I  SDHGMT+ G+HG  
Sbjct: 216 NGHAHRPSSREYKDNIKKVDDGVKEIV-SIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAG 274

Query: 293 SYEETDSLMLFIGLNSNISDYASAT----------------NNVAFQVDLAPTLALLFGV 336
              ET +  +  G         SA                      Q D+AP +A L GV
Sbjct: 275 HPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGV 334

Query: 337 PIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLRL---MLAQIQSSSFPRVSCNCFLD 393
           P P N+VG+L  G L +     +  ++  N+ Q+L      + Q + ++ P +     L 
Sbjct: 335 PFPLNSVGILPVGYLNNTG-LFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLL 393

Query: 394 GTCEGLDLDISECSGDKEKQLICLFRNAAALHGI-WKSKKSTESSSTMEDFSRALDAYNT 452
              + LD+     S  K+++   +      L  +  +      +   +         +  
Sbjct: 394 SDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVG 453

Query: 453 FLKTASEWLASKTTE--KPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRV---- 506
           ++   S  +    +   K     G     +LL  FI   V ++ F  +   P        
Sbjct: 454 WMSYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCL 513

Query: 507 CSLSNLLNLEEVFIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHL-LLLFKTAKSFKI 565
             +     +         L+  +     S     H++ + +V T  + +L+      + +
Sbjct: 514 LPVPIWYAVLREHEVIQDLVESLLTFPRS-----HFVAYLLVFTLGIEVLVLSFFYRYML 568

Query: 566 SKGMNILRDFKF-GSIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLI 624
           + G+ +   + F   ++                   T+L     W        V  +  +
Sbjct: 569 TAGLIVFAGWPFLTQLW--------------TRAKITFLS----WAFFSLLLAVFPLMPV 610

Query: 625 S-----IILVIGLGLY-----------------TLFRTGSNRKGVRILAFGFSTCGFLVL 662
                 + LV+G G                    L +       +++L+   S       
Sbjct: 611 VGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYST 670

Query: 663 LHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVLPWSALNKDKSFLAEVGDCLYLI 722
            H    ++ L           +   L++      +L    +++         +    Y  
Sbjct: 671 HHSLLKKEGLPLMNQIVSWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEA 730

Query: 723 GSAYILCWCLL------QQLLQQPINSGPILLLLLQIL-AILCLSSSDFQVNEWVEITAL 775
               +L   +       Q+ LQQP  S    L  +Q               ++      L
Sbjct: 731 LFPLVLSCLMFVWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFL 790

Query: 776 YYMGMAGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMF 817
            +  +   F  GN  ++ + D+A  +  ++  S  + G LM 
Sbjct: 791 VFFLLTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMM 832
>ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class N; endoplasmic
           reticulum membrane protein [Homo sapiens]
 gb|AAD11432.1| (AF109219) Mcd4p homolog [Homo sapiens]
          Length = 931

 Score =  731 bits (1867), Expect = 0.0
 Identities = 138/882 (15%), Positives = 279/882 (30%), Gaps = 129/882 (14%)

Query: 13  IFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLR 72
           +F   G+L+  +  +  +F  +   P + G++                  + L  P + R
Sbjct: 3   LFFTLGLLIHFVFFA-SIFDIYFTSPLVHGMTPQ---------------FTPLPPPAR-R 45

Query: 73  LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLK 132
           L+  V DGL A+ +   D            P+ ++++ + +     +    PT + P   
Sbjct: 46  LVLFVADGLRADALYELDENGN-----SRAPFIRNIIMH-EGSWGISHTRVPTESRPGHV 99

Query: 133 AMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFM----R 188
           A+++G       VA  +    +  D++  +           G    L +F          
Sbjct: 100 ALIAGFYEDVSAVAKGWKENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVY 155

Query: 189 HDGVSS----FFVKDTVQVDRNVSRHLPDELN------------SDDWNLLILHYLGLDH 232
                +    F  +D  ++D  V  ++ D  +            +++  +  LH LG+D 
Sbjct: 156 TYSYDAKREDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDT 215

Query: 233 VGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGS 292
            GH    +S      +K++DD V+ +          + G+T  I  SDHGMT+ G+HG  
Sbjct: 216 NGHAHRPSSRDYKHNIKKVDDGVKEIV-SMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAG 274

Query: 293 SYEETDSLMLFIGLNSNISDYASAT----------------NNVAFQVDLAPTLALLFGV 336
              ET + ++  G         SA                      Q D+AP +  L GV
Sbjct: 275 HPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGV 334

Query: 337 PIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLRL---MLAQIQSSSFPRVSCNCFLD 393
           P P N+VG+L    L +  D  +  ++  N+ Q+L      + Q +  + P +     L 
Sbjct: 335 PFPLNSVGILPVDYLNNT-DLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLL 393

Query: 394 GTCEGLDLDISECSGDKEKQLICLFRNAAALHGI-WKSKKSTESSSTMEDFSRALDAYNT 452
              +  ++     S  K ++   +      L  +  K      +          +  +  
Sbjct: 394 SDSKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVG 453

Query: 453 FLKTASEWLASKTTE--KPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRV---- 506
           ++  AS  +    +   K V       S +L   F+   + ++ F  +   P        
Sbjct: 454 WISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGL 513

Query: 507 CSLSNLLNLEEVFIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHL-LLLFKTAKSFKI 565
             L     +   F     L++ +     S     H++ + +  T  + +L+      + +
Sbjct: 514 LPLPIWYAVLREFQVIQDLVVSVLTYPLS-----HFVGYLLAFTLGIEVLVLSFFYRYML 568

Query: 566 SKGMNILRDFKF-GSIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLI 624
           + G+     + F   ++                   T L     W        V  +  +
Sbjct: 569 TAGLTAFAAWPFLTRLW--------------TRAKMTSLS----WTFFSLLLAVFPLMPV 610

Query: 625 S-----IILVIGLGLYT-----------------LFRTGSNRKGVRILAFGFSTCGFLVL 662
                 I LV+G GL                     +       +++L+   S       
Sbjct: 611 VGRKPDISLVMGAGLLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYST 670

Query: 663 LHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVLPWSALNKDKSFLAEVGDCLYLI 722
                 +  L           +   L+        L     ++         +    Y  
Sbjct: 671 QSSLLRKQGLPLMNQIISWATLASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEA 730

Query: 723 GSAYILCWCLL------QQLLQQPINSGPILLLLLQILA-ILCLSSSDFQVNEWVEITAL 775
               +L   +       Q+ LQQ        L  +Q              +++      L
Sbjct: 731 LFPLVLSCLMFVWINIEQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFL 790

Query: 776 YYMGMAGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMF 817
            +  +   F  GN  ++ + D+A  +  ++  S  + G LM 
Sbjct: 791 VFFLVTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMM 832
 Score =  716 bits (1830), Expect = 0.0
 Identities = 137/882 (15%), Positives = 273/882 (30%), Gaps = 135/882 (15%)

Query: 20  LLQIIG-------LSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLR 72
           LL               +F  +   P + G++                  + L  P + R
Sbjct: 2   LLFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQ---------------FTPLPPPAR-R 45

Query: 73  LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLK 132
           L+  V DGL A+ +   D            P+ ++++ + +     +    PT + P   
Sbjct: 46  LVLFVADGLRADALYELDENGN-----SRAPFIRNIIMH-EGSWGISHTRVPTESRPGHV 99

Query: 133 AMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFM----R 188
           A+++G       VA  +    +  D++  +           G    L +F          
Sbjct: 100 ALIAGFYEDVSAVAKGWKENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVY 155

Query: 189 HDGVSS----FFVKDTVQVDRNVSRHLPDELN------------SDDWNLLILHYLGLDH 232
                +    F  +D  ++D  V  ++ D  +            +++  +  LH LG+D 
Sbjct: 156 TYSYDAKREDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDT 215

Query: 233 VGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGS 292
            GH    +S      +K++DD V+ +          + G+T  I  SDHGMT+ G+HG  
Sbjct: 216 NGHAHRPSSRDYKHNIKKVDDGVKEIV-SMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAG 274

Query: 293 SYEETDSLMLFIGLNSNISDYASAT----------------NNVAFQVDLAPTLALLFGV 336
              ET + ++  G         SA                      Q D+AP +  L GV
Sbjct: 275 HPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGV 334

Query: 337 PIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLRL---MLAQIQSSSFPRVSCNCFLD 393
           P P N+VG+L    L +  D  +  ++  N+ Q+L      + Q +  + P +     L 
Sbjct: 335 PFPLNSVGILPVDYLNNT-DLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLL 393

Query: 394 GTCEGLDLDISECSGDKEKQLICLFRNAAALHGI-WKSKKSTESSSTMEDFSRALDAYNT 452
              +  ++     S  K ++   +      L  +  K      +          +  +  
Sbjct: 394 SDSKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVG 453

Query: 453 FLKTASEWLASKTTE--KPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRV---- 506
           ++  AS  +    +   K V       S +L   F+   + ++ F  +   P        
Sbjct: 454 WISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGL 513

Query: 507 CSLSNLLNLEEVFIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHL-LLLFKTAKSFKI 565
             L     +   F     L++ +     S     H++ + +  T  + +L+      + +
Sbjct: 514 LPLPIWYAVLREFQVIQDLVVSVLTYPLS-----HFVGYLLAFTLGIEVLVLSFFYRYML 568

Query: 566 SKGMNILRDFKF-GSIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLI 624
           + G+     + F   ++                   T L     W        V  +  +
Sbjct: 569 TAGLTAFAAWPFLTRLW--------------TRAKMTSLS----WTFFSLLLAVFPLMPV 610

Query: 625 S-----IILVIGLGLYT-----------------LFRTGSNRKGVRILAFGFSTCGFLVL 662
                 I LV+G GL                     +       +++L+   S       
Sbjct: 611 VGRKPDISLVMGAGLLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYST 670

Query: 663 LHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVLPWSALNKDKSFLAEVGDCLYLI 722
                 +  L           +   L+        L     ++         +    Y  
Sbjct: 671 QSSLLRKQGLPLMNQIISWATLASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEA 730

Query: 723 GSAYILCWCLL------QQLLQQPINSGPILLLLLQILA-ILCLSSSDFQVNEWVEITAL 775
               +L   +       Q+ LQQ        L  +Q              +++      L
Sbjct: 731 LFPLVLSCLMFVWINIEQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFL 790

Query: 776 YYMGMAGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMF 817
            +  +   F  GN  ++ + D+A  +  ++  S  + G LM 
Sbjct: 791 VFFLVTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMM 832
>dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N short form [Mus
           musculus]
          Length = 798

 Score =  706 bits (1804), Expect = 0.0
 Identities = 135/842 (16%), Positives = 268/842 (31%), Gaps = 129/842 (15%)

Query: 13  IFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLR 72
           +F   G+L+  +     +F  +   P + G++                  + L  P K R
Sbjct: 3   LFFALGLLIHFVFFV-SIFDIYFTSPLVHGMTPQ---------------FTPLPPPAK-R 45

Query: 73  LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLK 132
           L+  V DGL A+ +   D            P+ ++++ + +     +    PT + P   
Sbjct: 46  LVLFVADGLRADTLYELDEDGN-----SRAPFIRNVIMH-EGSWGVSHTRVPTESRPGHV 99

Query: 133 AMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFM----R 188
           A+++G       VA  +    +  D++  +           G    L +F          
Sbjct: 100 ALIAGFYEDVSAVAKGWKENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVY 155

Query: 189 HDGVSS----FFVKDTVQVDRNVSRHLPDELN------------SDDWNLLILHYLGLDH 232
                +    F   D  ++D  V   + D  +            +++  +  LH LG+D 
Sbjct: 156 TYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDT 215

Query: 233 VGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGS 292
            GH    +S      +K++DD V+ +          D G+T  I  SDHGMT+ G+HG  
Sbjct: 216 NGHAHRPSSREYKDNIKKVDDGVKEIV-SIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAG 274

Query: 293 SYEETDSLMLFIGLNSNISDYASAT----------------NNVAFQVDLAPTLALLFGV 336
              ET +  +  G         SA                      Q D+AP +A L GV
Sbjct: 275 HPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGV 334

Query: 337 PIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLRL---MLAQIQSSSFPRVSCNCFLD 393
           P P N+VG+L  G L +     +  ++  N+ Q+L      + Q + ++ P +     L 
Sbjct: 335 PFPLNSVGILPVGYLNNTG-LFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLL 393

Query: 394 GTCEGLDLDISECSGDKEKQLICLFRNAAALHGI-WKSKKSTESSSTMEDFSRALDAYNT 452
              + LD+     S  K+++   +      L  +  +      +   +         +  
Sbjct: 394 SDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVG 453

Query: 453 FLKTASEWLASKTTE--KPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRV---- 506
           ++   S  +    +   K     G     +LL  FI   V ++ F  +   P        
Sbjct: 454 WMSYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCL 513

Query: 507 CSLSNLLNLEEVFIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHL-LLLFKTAKSFKI 565
             +     +         L+  +     S     H++ + +V T  + +L+      + +
Sbjct: 514 LPVPIWYAVLREHEVIQDLVESLLTFPRS-----HFVAYLLVFTLGIEVLVLSFFYRYML 568

Query: 566 SKGMNILRDFKF-GSIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLI 624
           + G+ +   + F   ++                   T+L     W        V  +  +
Sbjct: 569 TAGLIVFAGWPFLTQLW--------------TRAKITFLS----WAFFSLLLAVFPLMPV 610

Query: 625 S-----IILVIGLGLY-----------------TLFRTGSNRKGVRILAFGFSTCGFLVL 662
                 + LV+G G                    L +       +++L+   S       
Sbjct: 611 VGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYST 670

Query: 663 LHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVLPWSALNKDKSFLAEVGDCLYLI 722
            H    ++ L           +   L++      +L    +++         +    Y  
Sbjct: 671 HHSLLKKEGLPLMNQIVSWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEA 730

Query: 723 GSAYILCWCLL------QQLLQQPINSGPILLLLLQIL-AILCLSSSDFQVNEWVEITAL 775
               +L   +       Q+ LQQP  S    L  +Q               ++      L
Sbjct: 731 LFPLVLSCLMFVWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFL 790

Query: 776 YY 777
           ++
Sbjct: 791 FF 792
>gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinositol glycan, class N [Mus
           musculus]
          Length = 826

 Score =  701 bits (1791), Expect = 0.0
 Identities = 135/848 (15%), Positives = 268/848 (30%), Gaps = 129/848 (15%)

Query: 13  IFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLR 72
           +F   G+L+  +  +  +F  +   P + G++                  + L  P K R
Sbjct: 3   LFFALGLLIHFVFFA-SIFDIYFTSPLVHGMTPQ---------------FTPLPPPAK-R 45

Query: 73  LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLK 132
           L+  V DGL A+ +   D            P+ ++++ + +     +    PT + P   
Sbjct: 46  LVLFVADGLRADTLYELDEDGN-----SRAPFIRNVIIH-EGSWGVSHTRVPTESRPGHV 99

Query: 133 AMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFM----R 188
           A+++G       VA  +    +  D++  +           G    L +F          
Sbjct: 100 ALIAGFYEDVSAVAKGWKENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVY 155

Query: 189 HDGVSS----FFVKDTVQVDRNVSRHLPDELN------------SDDWNLLILHYLGLDH 232
                +    F   D  ++D  V   + D  +            +++  +  LH LG+D 
Sbjct: 156 TYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDT 215

Query: 233 VGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGS 292
            GH    +S      +K++DD V+ +          D G+T  I  SDHGMT+ G+HG  
Sbjct: 216 NGHAHRPSSREYKDNIKKVDDGVKEIV-SIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAG 274

Query: 293 SYEETDSLMLFIGLNSNISDYASAT----------------NNVAFQVDLAPTLALLFGV 336
              ET +  +  G         SA                      Q D+AP +A L GV
Sbjct: 275 HPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGV 334

Query: 337 PIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLRL---MLAQIQSSSFPRVSCNCFLD 393
           P P N+VG+L  G L +     +  ++  N+ Q+L      + Q + ++ P +     L 
Sbjct: 335 PFPLNSVGILPVGYLNNTG-LFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLL 393

Query: 394 GTCEGLDLDISECSGDKEKQLICLFRNAAALHGI-WKSKKSTESSSTMEDFSRALDAYNT 452
              + LD+     S  K+++   +      L  +  +      +   +         +  
Sbjct: 394 SDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVG 453

Query: 453 FLKTASEWLASKTTE--KPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRV---- 506
           ++   S  +    +   K     G     +LL  FI   V ++ F  +   P        
Sbjct: 454 WMSYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCL 513

Query: 507 CSLSNLLNLEEVFIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHL-LLLFKTAKSFKI 565
             +     +         L+  +     S     H++ + +V T  + +L+      + +
Sbjct: 514 LPVPIWYAVLREHEVIQDLVESLLTFPRS-----HFVAYLLVFTLGIEVLVLSFFYRYML 568

Query: 566 SKGMNILRDFKF-GSIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLI 624
           + G+ +   + F   ++                   T+L     W        V  +  +
Sbjct: 569 TAGLIVFAGWPFLTQLW--------------TRAKITFLS----WAFFSLLLAVFPLMPV 610

Query: 625 S-----IILVIGLGLY-----------------TLFRTGSNRKGVRILAFGFSTCGFLVL 662
                 + LV+G G                    L +       +++L+   S       
Sbjct: 611 VGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYST 670

Query: 663 LHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVLPWSALNKDKSFLAEVGDCLYLI 722
            H    ++ L           +   L++      +L    +++         +    Y  
Sbjct: 671 HHSLLKKEGLPLMNQIVSWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEA 730

Query: 723 GSAYILCWCLL------QQLLQQPINSGPILLLLLQIL-AILCLSSSDFQVNEWVEITAL 775
               +L   +       Q+ LQQP  S    L  +Q               ++      L
Sbjct: 731 LFPLVLSCLMFVWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFL 790

Query: 776 YYMGMAGH 783
             +     
Sbjct: 791 ILLIFPVF 798
>pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragment)
 emb|CAB70839.1| (AL137607) hypothetical protein [Homo sapiens]
          Length = 825

 Score =  627 bits (1602), Expect = e-178
 Identities = 116/755 (15%), Positives = 230/755 (30%), Gaps = 106/755 (14%)

Query: 140 GGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFM----RHDGVSS- 194
                VA  +    +  D++  +           G    L +F               + 
Sbjct: 1   EDVSAVAKGWKENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAK 56

Query: 195 ---FFVKDTVQVDRNVSRHLPDELN------------SDDWNLLILHYLGLDHVGHTGGR 239
              F  +D  ++D  V  ++ D  +            +++  +  LH LG+D  GH    
Sbjct: 57  REDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRP 116

Query: 240 NSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDS 299
           +S      +K++DD V+ +          + G+T  I  SDHGMT+ G+HG     ET +
Sbjct: 117 SSRDYKHNIKKVDDGVKEIV-SMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLT 175

Query: 300 LMLFIGLNSNISDYASAT----------------NNVAFQVDLAPTLALLFGVPIPKNNV 343
            ++  G         SA                      Q D+AP +  L GVP P N+V
Sbjct: 176 PLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSV 235

Query: 344 GVLVPGTLCSLRDFEQLRALELNSWQLLRL---MLAQIQSSSFPRVSCNCFLDGTCEGLD 400
           G+L    L +  D  +  ++  N+ Q+L      + Q +  + P +     L    +  +
Sbjct: 236 GILPVDYLNNT-DLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFN 294

Query: 401 LDISECSGDKEKQLICLFRNAAALHGI-WKSKKSTESSSTMEDFSRALDAYNTFLKTASE 459
           +     S  K ++   +      L  +  K      +          +  +  ++  AS 
Sbjct: 295 ILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASL 354

Query: 460 WLASKTTE--KPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRV----CSLSNLL 513
            +    +   K V       S +L   F+   + ++ F  +   P          L    
Sbjct: 355 LIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWY 414

Query: 514 NLEEVFIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHL-LLLFKTAKSFKISKGMNIL 572
            +   F     L++ +     S     H++ + +  T  + +L+      + ++ G+   
Sbjct: 415 AVLREFQVIQDLVVSVLTYPLS-----HFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAF 469

Query: 573 RDFKF-GSIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLIS-----I 626
             + F   ++                   T L     W        V  +  +      I
Sbjct: 470 AAWPFLTRLW--------------TRAKMTSLS----WTFFSLLLAVFPLMPVVGRKPDI 511

Query: 627 ILVIGLGLYT-----------------LFRTGSNRKGVRILAFGFSTCGFLVLLHVGRYQ 669
            LV+G GL                     +       +++L+   S             +
Sbjct: 512 SLVMGAGLLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRK 571

Query: 670 DELSTGFGATVTVKVIYYLLSISSIGASLVLPWSALNKDKSFLAEVGDCLYLIGSAYILC 729
             L           +   L+        L     ++         +    Y      +L 
Sbjct: 572 QGLPLMNQIISWATLASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLS 631

Query: 730 WCLL------QQLLQQPINSGPILLLLLQILA-ILCLSSSDFQVNEWVEITALYYMGMAG 782
             +       Q+ LQQ        L  +Q              +++      L +  +  
Sbjct: 632 CLMFVWINIEQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTA 691

Query: 783 HFALGNSNTLATIDVAGAFIGISSHSTILSGILMF 817
            F  GN  ++ + D+A  +  ++  S  + G LM 
Sbjct: 692 FFGTGNIASINSFDLASVYCFLTVFSPFMMGALMM 726
>gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caenorhabditis elegans]
          Length = 929

 Score =  614 bits (1568), Expect = e-174
 Identities = 136/866 (15%), Positives = 262/866 (29%), Gaps = 125/866 (14%)

Query: 14  FTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRL 73
           F +A I + ++ L   +F  +   P + G+         F +S           P K R+
Sbjct: 5   FLIASITVHLV-LIYSIFDVYYTSPLVHGI------PPQFINSQ--------EAPAK-RI 48

Query: 74  LYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLKA 133
                DGL  +               +  PY  S++     I   +++  PT + P   A
Sbjct: 49  FIISADGLRYDTF---------NKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVA 99

Query: 134 MVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPG-----LFMR 188
           + +G       VA  +    +  D++  +         M G    + LF        F  
Sbjct: 100 IFAGITEDISAVAKGWKKNPVQFDSVFNRSS----YSWMWGSPDIVNLFDDLPNAESFSY 155

Query: 189 HDGVSSFFVKDTVQVDRNVSRHLPDELN------------SDDWNLLILHYLGLDHVGHT 236
                 F  KD   +D+ V  H  + L              +  ++  LH LG+D  GH 
Sbjct: 156 SADEEDFASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHG 215

Query: 237 GGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEE 296
               S      +K +D  +  +  + ++D      +T  +  SDHGMT+ G+HG  S +E
Sbjct: 216 NKPMSRQYIDNIKVVDSGIEKV--QHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDE 273

Query: 297 TDSLMLFIGLNSNISDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRD 356
             +  +  G                 Q+DLAP ++ L G PIP N++G+L    + S   
Sbjct: 274 VLTPFVAWGAGVK--QGGPK--LDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGS 329

Query: 357 FEQLRALELNSWQLLRLMLAQIQSSSFPRVSCNC--FLDGTCEGLDLDISECSGDKEKQL 414
             + +A+E N  QL   ++    + S          F D   E L   +++   D  +  
Sbjct: 330 SYEFKAIEANFKQLKEQIIFLKNAKSRRLWFRQFEKFGDKAMESLRTTLAQLGRD-RRFS 388

Query: 415 ICLFRNAAALHGIWKSKKSTESSSTMEDFSRALDAYNTFLKTASEWLASKTTEKPVLLLG 474
           +     A   H + ++             +    ++  ++     +L + T+++ + LL 
Sbjct: 389 VATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIALVVSFLHNSTSKENLSLLV 448

Query: 475 LG--VSAMLLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFIFALLLILVISMG 532
                   L    +  T + SL           +  +S L N  ++       +  +S  
Sbjct: 449 PHHLFIIPLACSLL-FTAYCSLSMTQTIYIILPIYLISILENHSKLTQRIREHVKALSAQ 507

Query: 533 S---SSMVEEEHYIWHFMVS-----TFHLLLLFKTAKSFKISKGMNILRDFKFGSIFSLL 584
               + ++  E ++  F+       T  +  +        ++    +L            
Sbjct: 508 PDWLNKVLSVEVFVKPFLGFVGFSITICI-FVLTFMDRAFLAAVFVLLMALP------QF 560

Query: 585 ISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLIS---------IILVIGLGLY 635
            S  ++  W +             WL       +                I+  I     
Sbjct: 561 YSHPIVSYWSKT------------WLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFL 608

Query: 636 --TLFRTGSNRKGVRIL--------AFGFSTCGFLVLLHVGRYQ---------------- 669
              L R     +  R+L        A  F            +                  
Sbjct: 609 CHRLSRRSCLTRIQRMLELMIYVQSATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQ 668

Query: 670 -DELSTGFGATVTVKVIYYLLSI-SSIGASLVLPWSALNKDKSFLAEVGDCLYLIGSAYI 727
             +  +         +   +++     G  LV    A          +    Y      I
Sbjct: 669 SLQPPSIARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLI 728

Query: 728 LCWCLLQQLLQQPINSGPILLLLLQILAILCLSSSDFQVNEWVEITALYYMGMAGHFALG 787
               L   +  +  +   + LL    L +     S  +  E           +   F  G
Sbjct: 729 FLVLLTLFVRFEFGHLSDVELL---QLKVDSTKISTGEYVELRRTVVCVSFVLCPLFGTG 785

Query: 788 NSNTLATIDVAGAFIGISSHSTILSG 813
           N  ++ + + +   + IS  S     
Sbjct: 786 NFASINSFNPSTLNLFISVFSPFTMA 811
>pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast
           (Schizosaccharomyces pombe)
 dbj|BAA21454.1| (AB004539) ORF YLL031c [Schizosaccharomyces pombe]
 emb|CAA16901.1| (AL021766) hypothetical protein [Schizosaccharomyces pombe]
          Length = 918

 Score =  608 bits (1552), Expect = e-172
 Identities = 191/853 (22%), Positives = 314/853 (36%), Gaps = 76/853 (8%)

Query: 13  IFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLR 72
           IF    ++    GL  F  GF   +  L+  S  E+      +    S           R
Sbjct: 26  IFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSG--CWAPKIFER 83

Query: 73  LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLK 132
            +  +ID L  +F++  +          + PY  S+L   ++      A  PT T  RLK
Sbjct: 84  AVIVIIDALRYDFLIPYNDS-NYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQRLK 142

Query: 133 AMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMRHDGV 192
            + +G++  F+D+  NF    + +DN+L Q+  +  ++V+LGD+TW  LF          
Sbjct: 143 GLTTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSLDKQIVLLGDDTWDVLFHDYLNETLSQ 202

Query: 193 S--SFFVKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVGHTGGRNSPLMPAKLKE 250
              SF V D   VD  V++++ D +   ++++LI HYLG+DHVGH  G + P M  KL +
Sbjct: 203 PAFSFNVPDLHGVDNKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQ 262

Query: 251 MDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLMLFIG--LNS 308
           MD  V+ M              TLLI++ DHGM   GNHGG S++E +S++         
Sbjct: 263 MDRCVKEMMDLL-------DDSTLLIVMGDHGMDNKGNHGGDSFDEINSVLWMYSKKPTF 315

Query: 309 NISDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRDFEQLRALELNSW 368
                     + A QVDL PTL+LL G PIP  N+G L+P       D    +A ++N  
Sbjct: 316 GYLKQPGKVLS-ANQVDLVPTLSLLLGNPIPYGNLGTLIPEPFYYYGDEYLSKAQKINIG 374

Query: 369 QLLRLMLAQIQSSSFPRVSCNCFLDGTCEGLDLDISECSGDKEKQLICLFRNAAALHGIW 428
           QL R        +S    S     + +         + + D                   
Sbjct: 375 QLNRFFSEYDLDASDFLSSSVHKNNNSYLDQYFLDFDYARDAFSYF-------------- 420

Query: 429 KSKKSTESSSTMEDFSRALDAYNTFLKTASEWLASKTTEKPVLLLGLGVSAMLLSCFICG 488
           K+  +  S   M      L         A          +    +   V   L  C I  
Sbjct: 421 KAIWAEFSLFPMIIG--FLLLIIGGFNLALLMQDKSVIFRMSANMAPSVMKCLPVCLILI 478

Query: 489 TVFLSLFKEVYHEPKDRVCSLSNLLN---------------LEEVFIFALLLILVISMGS 533
                L      E    + S   LLN               L+   IF   L  V S GS
Sbjct: 479 LANNELHSPFPAEFYVLLPSFYILLNSFNQKLMEYFKGFVKLDYFSIFITFL-HVCSFGS 537

Query: 534 SSMVEEEHYIWHFMVSTFHLLLLFKTAKSFKISKGMNILRDFKFGSIFSLLI---SGRLL 590
           +S    E  + HF++ T  L++  K           +      F  +  +     + R  
Sbjct: 538 NSFTVWEDRLCHFLIITIGLVMFCKCFSEMSPLFACSTYSALAFILLQVISSYVTNCREE 597

Query: 591 RGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLISIILVIGLGLYTLFRTGSNRKGVRI- 649
           +G       +     IS       +  V  +    +  +I   +  L         +++ 
Sbjct: 598 QG------AFCVSTYISTPDNSLRTLIVLALMA--LSSIILPLILQLHLRRVLGLSLKLY 649

Query: 650 -LAFG----FSTCGFLVLLHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVLPWSA 704
            L+        +  F +  HV  + ++            V+Y L +   I    VL W  
Sbjct: 650 HLSILYFFELISSIFWIAHHV--FANDALLEKQY---HHVLYSLANTYVICILGVLIWQF 704

Query: 705 LNKDKSFLAEVGDCLYLIGSAYILCWCLLQQLLQQPINSGPILLLLLQILAILCLSS--S 762
               +S  A++      I  +Y +   L   L       G + L    +  +L +     
Sbjct: 705 FLLSRSKFAKINV----IERSYFVFALLYSFLSFLQRPLGHLSLFSCFLQILLLIQLKQW 760

Query: 763 DFQVNEWVEITALYYMGMAGHFALGNSNTLATIDVAGAF-IGISSHSTILSGILMFMITY 821
              V        L  +G++  F  GN   ++++D   AF    S+ +  +S I MF+ T 
Sbjct: 761 QPSVGHNFFSVTLGLLGLSHFFTTGNQAAISSLDWNFAFIHSKSAENQAISAIFMFLHTV 820

Query: 822 ASPMLFLLSLVMY 834
            +P+L  +S+ ++
Sbjct: 821 GAPILTCISIPLF 833
>gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melanogaster]
          Length = 880

 Score =  597 bits (1523), Expect = e-169
 Identities = 217/856 (25%), Positives = 352/856 (40%), Gaps = 93/856 (10%)

Query: 13  IFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLR 72
           ++T+  +   + G  +F+ GFFP   ++   +  ES       ++L+  E     P    
Sbjct: 9   VYTIGMLTAFLCGAVLFLIGFFPASYSV---AEKESTVPEGRPTALLGMELTPPPPAYDS 65

Query: 73  LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLK 132
            +  ++D L  +F               SMP   S                PTVTMPRLK
Sbjct: 66  FVLLLVDALRDDFPDAT-----------SMPVAYSRACE----KLKLHVDIPTVTMPRLK 110

Query: 133 AMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMRH-DG 191
           ++ +G +  F+D+A N      + D+ L +  +    +   GD TW+KLFP  F R  + 
Sbjct: 111 SITTGTLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVEN 170

Query: 192 VSSFFVKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVGHTGGRNSPLMPAKLKEM 251
             SF+V D  + DRNV++ L  EL   DW+LLILHYLGLDH+GH  G  SP +P KLKEM
Sbjct: 171 HDSFYVNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEM 230

Query: 252 DDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLMLFIGLNSNIS 311
           D++V+ +               LL++  DHGM + G HGG++  ET   +     N + +
Sbjct: 231 DEVVKKILD------HKSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLYYNNCSKT 284

Query: 312 DYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLL 371
             AS       Q+DLAPTL++L  V IP  ++G L+P  L SL    QL A   N+  LL
Sbjct: 285 PSASKRY---NQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLL 341

Query: 372 RLMLAQIQSSSFPRVS-CNCFLDGTCEGLDLDISECSGDKEKQLICLFRNAA------AL 424
                +       R      + + T     L      GD        ++NA        L
Sbjct: 342 NKARVKFGHEIVHRSDYYTWYQNATLLHKKLLRPLREGDGGGASQVYYQNAKLNYMRLQL 401

Query: 425 HGIWKSK--KSTESSSTMEDFSRALDAYNTFLKTASEWLASKTTEKPVLLLGLGVSAMLL 482
            G+   +   S  ++  +   S ALD   T            ++    +LL + +S    
Sbjct: 402 DGLKVGQLWLSVIAAVVLNYTSHALDIIMT------------SSTLYSILLLVPISI--- 446

Query: 483 SCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFIFALLLILVISMGSSSMVEEEHY 542
           + ++   V  +L K        R   +S  L L    + A   I  +++GSSS +E E+ 
Sbjct: 447 AVYLTIDVAQALLKIALPPLYTRRLKISIPLPLP---LLACYAIRTLTLGSSSFIEFEYN 503

Query: 543 IWHFMVSTFHLLLLFKTAKSFKISKGMNILRDFKFGSIFSLLISGRLLRGWHQGGVNWTY 602
            W+++ +T  LL  F+T               ++       L +GR L       + W  
Sbjct: 504 TWYYLGNTLILLTAFRT-------------LRWRITKTNVEL-NGRHLYTIASTCL-WQM 548

Query: 603 LPDISKWLVQGGSGYVKWIQLI---SIILVIGLGLYTLFRTGSNRKGVRILAFGFSTCGF 659
              +   ++     Y+  +Q I    +I  + L    L R     + +   A  F    F
Sbjct: 549 RKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLLLWARLHRHSQLPQSLASGAALFMVYCF 608

Query: 660 LVLLHVGRYQDELSTGFGATVTVKVIYY---LLSISSIGASLVLPWSALNKDKSFLAEVG 716
             L     + D  S      +   ++ +   L  +  +G    LP          +   G
Sbjct: 609 RGLNGQVLFFDVPSHMAAKLMVPTLVIFWCCLALVLMLGYRAALPQ---AHSFGKVPPTG 665

Query: 717 DCLYLIGSAYILCWCLLQQLLQQPINS--GPILLLLLQILAILC--------LSSSDFQV 766
             L  +    +    LL  LLQ+  N    P+LL+ LQ    LC          S     
Sbjct: 666 -ALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVYGTSARKFSVRLV- 723

Query: 767 NEWVEITALYYMGMAGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMFMITYASPM- 825
               +I    ++     F  GNSN+L+TID+   +IG ++++  +  I + + TY++ + 
Sbjct: 724 -HVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIFVTLNTYSADIH 782

Query: 826 LFLLSLVMYIGANLRN 841
            FL  +V  + ++LR+
Sbjct: 783 AFLYLVVHTLRSDLRS 798
>pir||T40715 hypothetical protein SPBC839.08c - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA17011.1| (AL021816) hypothetical protein [Schizosaccharomyces pombe]
 emb|CAB46701.1| (AL096796) hypothetical protein [Schizosaccharomyces pombe]
          Length = 935

 Score =  588 bits (1502), Expect = e-167
 Identities = 116/889 (13%), Positives = 256/889 (28%), Gaps = 139/889 (15%)

Query: 14  FTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRL 73
             + GIL  ++ L   +F  + V P + G+                   S    P K RL
Sbjct: 5   LLLLGILFHVVFLK-SIFDIYFVTPLIHGMKQY----------------SAGEAPAK-RL 46

Query: 74  LYQVIDGLPAEFVLGKDGKPPEKVLK-ESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLK 132
              V DGL  + +L    +      +  + P+ +S++ N       +    PT + P   
Sbjct: 47  FLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNN-GTFGVSHTRVPTESRPGHV 105

Query: 133 AMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMRHDGV 192
           A+++G       V   +    +  D++  Q           G E  L +F         V
Sbjct: 106 ALIAGFYEDVSAVTKGWKKNPVNFDSVFNQS----RHTYSFGSEDILPMFSEGASDPSRV 161

Query: 193 SSFFVKDTVQ--------VDRNVSRHLP------------DELNSDDWNLLILHYLGLDH 232
            +F     ++        +D  V   L              ++   D  +  LH LG+D 
Sbjct: 162 DTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDT 221

Query: 233 VGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGS 292
           +GH    +S      ++ +D  ++ +  +   +  ++ G +  +  +DHGM++ G+HG  
Sbjct: 222 IGHNKHPDSVEYVENIQYIDGKIQELVDKM-NNYYNNDGASSWVFTADHGMSDFGSHGDG 280

Query: 293 SYEETDSLMLFIGLNSNIS----DYASATNN-----------VAFQVDLAPTLALLFGVP 337
           + + T + ++  G          +Y     +              Q D+A  ++ L G+ 
Sbjct: 281 NLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLN 340

Query: 338 IPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLRLMLAQIQSSSFPRVSCNCFLDGTCE 397
            P N+VG +    L       +     +N+ ++       ++S+S  + S          
Sbjct: 341 FPVNSVGQIPLDYL-DCSSRRKAEVALMNALEIGEQY--NLKSASKDQTSIFFRPYSPLR 397

Query: 398 GLDLDISECSG------DKEKQLICLFRNAAALHGIWKSKKSTESSSTMEDFSRALDAYN 451
                 +          +  +  I +         +    +  +    +   S     Y 
Sbjct: 398 NYTEVQASFYNSVIADIESGEYEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYL 457

Query: 452 TFLKTASEWLASKTTEKPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRVCSLSN 511
           +++     ++ S   E P   +   VS +    F    + + +F  +   P         
Sbjct: 458 SWIGYVICFVFSLNIE-PSSKIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYG---- 512

Query: 512 LLNLEEVFIFALLLILVISMGSSSMVEEEHYIW-----------HFMVSTFHLLLLFKT- 559
              L       L LI  I    ++ +  ++++              +  +  +L L +  
Sbjct: 513 -YALFPTI--FLQLIHSI--FPNTKLGFKNFLTVAKQKHGFSLLKILFISLCILCLLQFI 567

Query: 560 AKSFKISKGMNILRDFKFGSIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVK 619
             S+   +G +++        + L                +++      W V        
Sbjct: 568 VYSYFHREGFSVILMGLAAWPWLLHADY-----------AFSHKTISVSWSVLTSLLCFF 616

Query: 620 WIQLI----SIILVIGLGL--------------YTLFRTGSNRKGVRILAFGFSTCGFLV 661
            I  +    S++ +   G                  F+  S     +++           
Sbjct: 617 TILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQYSSTVTNKQLVLQVLIIM---A 673

Query: 662 LLHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVLP---------WSALNKDKSFL 712
            + V     + S      +   +      +      +               L       
Sbjct: 674 TVPVTLKIAD-SLQRNIAIPPILRLVAFGLFITSYIIPSHHIRSCKHYFLDRLAILFLTF 732

Query: 713 AEVGDCLYLIGSAYILCWCLLQQLLQQPINSGPILLLL----LQILAILCLSSSDFQVNE 768
           +     L +   A       +   L   + +                          ++ 
Sbjct: 733 SPTMCMLSISFEALFYVVLFITLGLWMELETELQKYTEQLHPEYSRKKDAKF--HLSLSH 790

Query: 769 WVEITALYYMGMAGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMF 817
                  Y       F  GN  +L+T  +      I   + +  G L+ 
Sbjct: 791 IRISLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQGALLM 839
>ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; Mcd4p [Saccharomyces
           cerevisiae]
 sp|P36051|YKQ5_YEAST HYPOTHETICAL 105.7 KD PROTEIN IN TPK3-PIR1 INTERGENIC REGION
 pir||S37786 hypothetical protein YKL165c - yeast (Saccharomyces cerevisiae)
 emb|CAA81489.1| (Z26877) unknown [Saccharomyces cerevisiae]
 emb|CAA82007.1| (Z28165) ORF YKL165c [Saccharomyces cerevisiae]
 prf||2118404A ORF [Saccharomyces cerevisiae]
          Length = 919

 Score =  576 bits (1470), Expect = e-163
 Identities = 133/885 (15%), Positives = 264/885 (29%), Gaps = 141/885 (15%)

Query: 9   TRLTIFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHP 68
           TR T+  V  +   +  L   +F  + + P + G+S  +S                   P
Sbjct: 5   TRTTLLAVGVLF-HLFYL-WSIFDIYFISPLVHGMSPYQSTPT---------------PP 47

Query: 69  EKLRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTM 128
            K RL   V DGL A+    K   P     +   P+ +SL+ N  A    +    PT + 
Sbjct: 48  AK-RLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNN-ATYGISHTRMPTESR 105

Query: 129 PRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMR 188
           P   AM++G       V   + +  +  D+   Q           G    L +F      
Sbjct: 106 PGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQS----THTYSFGSPDILPMFKDGASD 161

Query: 189 HDGVSSFFV--------KDTVQVDRNVSRHLPDELNSD------------DWNLLILHYL 228
            + V ++          + ++++D  V RHL    ++             D N+  LH L
Sbjct: 162 PNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLL 221

Query: 229 GLDHVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGN 288
           G D  GH+    S      +K +DD +  +     +++     +T  I  +DHGM+  G+
Sbjct: 222 GCDTAGHSYRPYSAEYYDNVKYIDDQIPILID--KVNKFFADDKTAFIFTADHGMSAFGS 279

Query: 289 HGGSSYEETDSLMLFIGLNSNIS---------------DYASATNNVAFQVDLAPTLALL 333
           HG      T + ++  G   N                 + +S   N   Q D+A  ++ L
Sbjct: 280 HGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYL 339

Query: 334 FGVPIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLRLMLAQIQSSSFPRVSC----N 389
            GV  PKN+VG L        ++ ++L AL  N+  +L   L +       +        
Sbjct: 340 IGVNYPKNSVGELPIAY-IDGKESDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFK 398

Query: 390 CFLDGTCEGLDLDISECSGDKEK---QLICLFRNAAALHGI-WKSKKSTESSST-----M 440
                    L+   +      E               L  I  +      + +      +
Sbjct: 399 FVEKSHSHYLEEIETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTI 458

Query: 441 EDFSRALDAYNTFLKTASEWLASKTTE--KPVLLLGLGVSAMLLSCFICGTVFLSLFKEV 498
             F      + +F+     ++     +  K   L            F    + L+     
Sbjct: 459 VTFGFVGWIFFSFIIFLKSFILENVIDDQKASPLSHA--------VFGSIGILLNWILFY 510

Query: 499 YHEPKDRVCSLS-NLLNLEEVFIFALLLILVISMGSSSMVEEEHY---IWHFMVSTFHLL 554
            H P +    L   L          +     +     S ++E       W  ++ T  ++
Sbjct: 511 QHSPFNFYMYLLFPLYFWSY-----IFTNRSVL---RSGIKEFFKGTSPWKRVLITISII 562

Query: 555 LLFKTAKSFKISKGMNILRDFKFGSIFSLLISGRLLRGWHQGGVN--WTYLPDISKWLVQ 612
            +++                + F  I ++L     + G  +  VN  W     +      
Sbjct: 563 SVYE-------GIVYGFFHRWTFTLITNILAFYPFICGVRELSVNILWIITSVLLSTFTL 615

Query: 613 GGSGYVKWIQLISI--ILVIGLGLYTLFR---------TGSNRKGVRILAFGFSTCGFLV 661
             +  ++ +  I +  +L+I    Y L++                + ++A   +      
Sbjct: 616 FDAVKIEDLNQIHLAGLLIILSAFYALYKIHSRINSYTRAIFAIQISLVAAMLAVT--HR 673

Query: 662 LLHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVLPWSALNKDKSFLAEVGDCLYL 721
            +   + +  L         +     L  +  +                      D    
Sbjct: 674 SVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYR---------------KPNNDYKVR 718

Query: 722 IGSAYILCWCLLQQLLQQPINSGPILLLLLQILAILCLSSSDFQVNE--------WVEIT 773
           +   Y+        L     +    L     +  I   +       +             
Sbjct: 719 LLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEMKTQKDENWLQVLRVSV 778

Query: 774 ALYYMGMAGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMFM 818
             +++     F  GN  ++++  +      +      L G L+ +
Sbjct: 779 IGFFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGALLML 823
>gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melanogaster]
          Length = 874

 Score =  518 bits (1321), Expect = e-145
 Identities = 113/846 (13%), Positives = 240/846 (28%), Gaps = 141/846 (16%)

Query: 16  VAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRLLY 75
              +++  + L   +F  +   P ++G++  +                 L  P   RL+ 
Sbjct: 4   AYALVVH-VLLLGSIFVIYFRSPVITGLTPQKHLLYYG-----------LEPPA-NRLVL 50

Query: 76  QVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLKAMV 135
            V DG  A+    ++           +P  +  +   + +   ++   PT T P    ++
Sbjct: 51  IVTDGFRADSFFEENC--------RYVPNLRK-IFLREGVVGVSRTRVPTETRPGHITLI 101

Query: 136 SGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFM------RH 189
           +G       V   + +  +  D +  +  +        G    L +F  +        R 
Sbjct: 102 AGLYEDPSAVLRGWKSNPIDFDTVFNRSSQ----TYAWGANDVLNVFSHVSNGGEINLRF 157

Query: 190 DGVSSFFVK--DTVQVDRNVSRHL-------PDELNSDDWNLLILHYLGLDHVGHTGGRN 240
                 F    D  + D  V + +        + L      +  LH LGLD  GH     
Sbjct: 158 YNHDLDFSPGYDAYEEDEWVFKRVKLLLQQKREALQRAQNVVFFLHLLGLDTAGHVHKPG 217

Query: 241 SPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSL 300
           +P     L++ +  V  ++     +R     +T  ++ +DHGMT++G             
Sbjct: 218 APKFRRTLEKTEKGVYAIYQ--EFERVFPDKRTAYLLTADHGMTDSGA-------SRAVP 268

Query: 301 MLFIGLNSNISDYASA-TNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRDFEQ 359
               G     ++   A   +   Q  L P ++ L G+  P NN G L  G L   +   +
Sbjct: 269 KPG-GRTFMPNNEGPAMPLHELEQAQLTPLMSALLGLAPPMNNFGKLPLGYLNVSK-EYE 326

Query: 360 LRALELNSWQLLRLMLAQIQSSSFPRVS------CNCFLDGTCEGLDLDISECSGDKEKQ 413
             A  +N+ QLL   +A  +       +           +      D  +      K + 
Sbjct: 327 AMAAHVNALQLLEQYVALQKQHKKGFFADILLEYDVLNAEAIKRYKDTIVQ--LQKKREY 384

Query: 414 LICLFRNAAALHGIWKSKKSTESSSTMEDFSRALDAYNTFLKT----------ASEWLAS 463
            +C+ ++   +    +                    +  ++            +   L  
Sbjct: 385 SLCIDKSQVIMSQALEGIDYYHGYYRRVLLLSTTSTFLGWMFYIYRLLSRNRASKVELVL 444

Query: 464 KTTEKPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFIFAL 523
           + + K V +  +    +L+ C +     L +   +       + +L              
Sbjct: 445 ERSNKIVRVSIVSSVIVLIICLLSQGTPLDISFYLLLPYFVWLKALQPWN---------- 494

Query: 524 LLILVISMGSSSMVEEEHYIWHFMVSTFHLLLLFKTAKSFKISKGMNILRDFKFGSIFSL 583
                    SSS      Y    + ++   L+L        +               F +
Sbjct: 495 ------INFSSS--PASAYSVPALQTSMWQLVLLIACAELMVFTFFERRL---IALCFCV 543

Query: 584 LISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLISI--ILVIGLGLYTLFRTG 641
                    W      W    D   WL          +  +S+       LG   +    
Sbjct: 544 FACYN---SWEN--FQW-KSRDFFSWLALVLILSCFPLLPLSVGYQNGYLLGAGVIVIFT 597

Query: 642 SN--------------RKGVRILAFGFSTCGFLVLLHVGRYQDELSTGFGATVTVKVIYY 687
           ++              +    ++      C +L    +      +         + ++Y 
Sbjct: 598 NSFWNSKSRLCYRNHTKYSNALILLQTILCAYLHSNGI-----NIPIPLKLASWLYLVYA 652

Query: 688 LLSISSI-GASLVLPWSALNKDKSFLAEVGDCLYLIGSAYILCWCLLQQLLQQPINSGPI 746
             SI     + L L  + +  +   L       Y                         +
Sbjct: 653 FASILLSKESRLDLRLAQIGFNLGSLYATLCTSYEAVF---------------------V 691

Query: 747 LLLLLQILAILCLSSSDFQVNEWVEITALYYMGMAGHFALGNSNTLATIDVAGAFIGISS 806
            LL +++   L   S+  + +       L        F  GN  ++++ D   A   +S 
Sbjct: 692 QLLTIELNISLRAQSARAERSVLRLAFTLLLYTFFSLFGSGNIASISSFDPNIARCYLSH 751

Query: 807 HSTILS 812
            +  + 
Sbjct: 752 FAPFVI 757
>ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class O [Mus musculus]
 dbj|BAA96254.1| (AB038560) Pig-o [Mus musculus]
          Length = 1101

 Score =  479 bits (1222), Expect = e-134
 Identities = 146/594 (24%), Positives = 227/594 (37%), Gaps = 65/594 (10%)

Query: 13  IFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLI--SNESELHHPEK 70
           +F      L   G+++F  GF   +  L+  S  +    P            +       
Sbjct: 16  LFLAWVCFLFYAGIALFTSGFLLTRLELTNQSSCQELPGPGPLPWGSHGKPGACWMPSRF 75

Query: 71  LRLLYQVIDGLPAEFVLGKDGK-----PPEKVLKESMPYTQSLL--ANGDAIGYHAKAAP 123
            R++  +ID L  +F   +        P        +   Q +L         Y ++  P
Sbjct: 76  SRVVLVLIDALRFDFAQPQRSHVPGEPPVSVPFLGKLGSLQRILESQPHHGRLYRSQVDP 135

Query: 124 PTVTMPRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFP 183
           PT TM RLKA+ +G++  F+D   NF + A+++DN++ Q    G ++V +GD+TW  LFP
Sbjct: 136 PTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNVIQQLNSAGRRVVFMGDDTWRDLFP 195

Query: 184 GLFMRHDGVSSFFVKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVGHTGGRNSPL 243
           G F +    SSF V+D   VD  +  HL   L+   W++LI H+LG+DH GH  G + P 
Sbjct: 196 GAFSQAFFFSSFNVRDLHTVDNGILEHLYPTLDGGSWDVLIAHFLGVDHCGHKHGPHHPE 255

Query: 244 MPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLMLF 303
           M  KL +MD +++ +  R   D       TLL++  DHGMT NG+HGG S  E  + +  
Sbjct: 256 MAKKLSQMDQVIQGLIERLEND-------TLLVVAGDHGMTMNGDHGGDSELEVSAALFL 308

Query: 304 IGLNSNISDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRD------- 356
               +           V  QV L PTLALL G+PIP  N G ++        D       
Sbjct: 309 YSPTALFPSVPPEEPEVIPQVSLVPTLALLLGLPIPFGNTGEVMAELFSGGSDSSHPHSS 368

Query: 357 -FEQLRALELNSWQLLRLMLAQ------IQSSSFPRVSCNCFLDGTCEGLDLDISECSGD 409
              Q+ AL +N+ Q+ R +         +Q     R+                      D
Sbjct: 369 ALAQVSALHINAQQVSRFLHTYSAATQDLQVKELHRLQTLFSKASARYQ------HFLRD 422

Query: 410 KEKQLICLFRNAAALHGIWKSK-------KSTESSSTMEDFSRALDAYNTFLKTASEWLA 462
            ++    L    A      +          +  S   M     AL A    L   +  LA
Sbjct: 423 PQEAEAALSTLTAEFQQFLRGARALCIESWARFSLVRM-AGGAALLAAACLLCLLASQLA 481

Query: 463 SKTTEKPVLLLGLGVSAMLLSCFI------------------CGTVFLSLFKEVYHEPKD 504
                    LL + V+  L    +                        SL   ++     
Sbjct: 482 VAPGFLFRPLLLIPVAWGLTWTILYAGVSVTTGSKIDLVVLGAVAAAGSLLPFLWKAWVS 541

Query: 505 RV--CSLSNLLNLEEVFIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHLLLL 556
           R     L+ LL +    +  LLLI + +  S S    E     F++ +    L+
Sbjct: 542 RGSKRPLAPLLPVPRP-VLILLLIRLATFFSDSFFVVEARATPFLLGSLVFFLV 594
>pir||T02245 hypothetical protein P1.11659_3 - human
 gb|AAC07985.1| (AC004472) P1.11659_3 [Homo sapiens]
          Length = 880

 Score =  447 bits (1140), Expect = e-124
 Identities = 119/451 (26%), Positives = 188/451 (41%), Gaps = 49/451 (10%)

Query: 13  IFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNES--ELHHPEK 70
           +F      L   G+++F  GF   +  L+  S  +    P         +          
Sbjct: 8   LFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGACWMASRF 67

Query: 71  LRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPR 130
            R++  +ID L  +F   +      +            +    A  Y ++  PPT TM R
Sbjct: 68  SRVVLVLIDALRFDFAQPQHSHRILE------------IQPHHARLYRSQVDPPTTTMQR 115

Query: 131 LKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMRHD 190
           LKA+ +G++  F+D   NF + A+++DN++ Q    G ++V +GD+TW  LFPG F +  
Sbjct: 116 LKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDDTWKDLFPGAFSKAF 175

Query: 191 GVSSFFVKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVGHTGGRNSPLMPAKLKE 250
              SF V+D   VD  +  HL   ++S +W++LI H+LG+DH GH  G + P M  KL +
Sbjct: 176 FFPSFNVRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQ 235

Query: 251 MDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLMLFIGLNSNI 310
           MD +++ +  R   D       TLL++  DHGMT NG+HGG S  E  + +      +  
Sbjct: 236 MDQVIQGLVERLEND-------TLLVVAGDHGMTTNGDHGGDSELEVSAALFLYSPTAVF 288

Query: 311 SDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRD-------FEQLRAL 363
                    V  QV L PTLALL G+PIP  N+G ++        D         Q  AL
Sbjct: 289 PSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASAL 348

Query: 364 ELNSWQLLRLMLAQ------IQSSSFPRVSCNC-FLDGTCEGLDLDISECSGDKEKQLIC 416
            LN+ Q+ R +         +Q+    ++           + L           +     
Sbjct: 349 HLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWL-------LQSPKGAEAT 401

Query: 417 LFRNAAALHGIWKSK-------KSTESSSTM 440
           L    A L    +          +  S   M
Sbjct: 402 LPTVIAELQQFLRGARAMCIESWARFSLVRM 432
>ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
 gb|AAF24617.1|AC010870_10 (AC010870) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
          Length = 921

 Score =  440 bits (1121), Expect = e-122
 Identities = 137/886 (15%), Positives = 260/886 (28%), Gaps = 134/886 (15%)

Query: 10  RLTIFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPE 69
           R T   V G+ L  +   + +F  +   P + G+         F              P 
Sbjct: 42  RETWLVVLGVALHAVY-MLSIFDIYFKTPIVHGMDP---VPPRFS-----------EPPA 86

Query: 70  KLRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMP 129
           K RL+  + DGL A+     D +      K   P+ ++++ N       + A PPT + P
Sbjct: 87  K-RLVLLISDGLRADKFFEPDEEG-----KYRAPFLRNIIKN-QGRWGVSHARPPTESRP 139

Query: 130 RLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLF-----PG 184
              A+++G       V   +    +  D++  Q           G    + +F       
Sbjct: 140 GHVAIIAGFYEDPSAVTKGWKANPVEFDSVFNQS----RHTFAFGSPDIIPIFCSALPHS 195

Query: 185 LF-MRHDGVSSFFVKDTVQVDRNVSRHLPDELNSD------------DWNLLILHYLGLD 231
            +         F   D   +D          LN              D  ++ LH LG D
Sbjct: 196 TWNSYPHEYEDF-ATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCD 254

Query: 232 HVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGG 291
             GH     S +    +K +D I   ++        +   +T  I  +DHGM++ G+HG 
Sbjct: 255 SNGHAHRPYSSIYLNNVKVVDKIAERVYHLLED--YYRDNRTSYIFTADHGMSDKGSHGD 312

Query: 292 SSYEETDSLMLFIGLNSNISDYASA-----------------------------TNNVAF 322
                TD+ ++  G        AS                                    
Sbjct: 313 GHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVN 372

Query: 323 QVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLRLMLA--QIQS 380
           Q D+AP ++ L G+P P N+VG L  G +    + E++ A+  N+ Q+L  +L    I+S
Sbjct: 373 QADIAPLMSTLLGLPCPVNSVGNLPLGYMKL-NEAEEVEAVVANTKQILNQLLRKSYIKS 431

Query: 381 SSFPRVSCNCFLDGT----CEGLDLDISECSGDKEKQLICLFRNAAALHGIWKSKKSTES 436
            S                    +D  IS  S +   +L    RN +      +     ++
Sbjct: 432 -SNSLFFKPFKPLVHHSFSLSQIDELISAKSYEAAMKLAVDLRNLS-----LEGLHYFQT 485

Query: 437 SSTMEDFSRALDAYNTFLKTASEWLASKTTEKPVLL-----LGLGVSAMLLSCFICGTVF 491
              +   +     Y  ++   +  +    +     L     L + +S  LL   +     
Sbjct: 486 YDWLMLMTVITLGYTGWMIVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNL 545

Query: 492 LSLFKEVYHEP--------------KDRVCSLSNLLNLEEVFIFALLLILVISMGSS--- 534
           +     +YH                   +  L   L       F  LL            
Sbjct: 546 VEHSPPLYHAYIGMTVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVEL 605

Query: 535 ---SMVEEEHYIWHFMVSTFHLLLLFKTAKSFKISKGMNILRDFKFGSIFSLLISGRLLR 591
              S  E + Y W F+++     +L   +  ++    + +     F S+F+L+ +   + 
Sbjct: 606 LVHSFTERKLYTWFFLIAGVVASILLHFSIPWRSGIPVFVCISCWFLSVFTLMPA--EIP 663

Query: 592 GWHQGGVNW--TYLPDISKWLVQGGSGYVK--WIQLISIILVIGLGLYTLFRTGSNRKGV 647
             +     +      DI  W V     +V         I  V  +      R  +     
Sbjct: 664 DNNNLVSPFLGANDTDIFGWCVICDGVFVDKASNAESRIAFVTSVHKLVSCRYEAVFYSA 723

Query: 648 RILAFGFSTCGFLVLLHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVLPWSALNK 707
             +             H  + ++   +       + +      +      + L +  L  
Sbjct: 724 LAVVLMAWILFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLVFMVL-F 782

Query: 708 DKSFLAEVGDCLYLIGSAYILCWCLLQQLLQQPINSGPILLLLLQILAI----LCLSSSD 763
           + +F                +   +               L +  +L I           
Sbjct: 783 NVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKLVR 842

Query: 764 FQVNEWVEITALYYMGMA--GHFALGNS-------NTLATIDVAGA 800
                   +  L+   M     F + N+       N+++   +  A
Sbjct: 843 VPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVSA 888
 Score = 63.0 bits (152), Expect = 2e-08
 Identities = 61/487 (12%), Positives = 145/487 (29%), Gaps = 69/487 (14%)

Query: 379 QSSSFPRVSCNCFLDGTCEGLDLD-ISECSGDKEKQLICLFRNAAALHGIWKSKKSTESS 437
           Q+   P +S    L      +    +     ++ +++  +  N   +      K   +SS
Sbjct: 373 QADIAPLMSTLLGLPCPVNSVGNLPLGYMKLNEAEEVEAVVANTKQILNQLLRKSYIKSS 432

Query: 438 STMEDFSRALDAYNTFLKTASEWLASKTTEKPVLLLGLGVSAMLLSCFICGTVFLSLFKE 497
           +++         +++F  +  + L S  + +  + L +                 +L  E
Sbjct: 433 NSLFFKPFKPLVHHSFSLSQIDELISAKSYEAAMKLAVD--------------LRNLSLE 478

Query: 498 VYHEPKDR-VCSLSNLLNLEEVFIFALLLILVISMGSS---SMVEEEHYIWHFMVSTF-H 552
             H  +      L  ++ L       +L + V+   SS    + ++EH   +        
Sbjct: 479 GLHYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMA 538

Query: 553 LLLLFKTAKSFKISKGMNILRDFKFGSIFSLLISGRLLRG-WHQGGVN----WTYL---- 603
           +L +    +        +            +    RL+RG W          +  L    
Sbjct: 539 ILSVLNLVEHSPPL--YHAYIGMTVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAA 596

Query: 604 ------PDISKWLVQGGSGYVKWIQLISIILVIGLGLYTLFRTGSNRKGVRILAFGFSTC 657
                  ++          Y  +  +  ++  I L     +R+G          F   +C
Sbjct: 597 AVAVVIVELLVHSFTERKLYTWFFLIAGVVASILLHFSIPWRSGIPV-------FVCISC 649

Query: 658 GFLVLLHVGRYQDELSTGFGATVTVKVIYYL-------LSISSIGASLVLPWSALNKDK- 709
            FL +        E+              +L            I   + +  ++  + + 
Sbjct: 650 WFLSVF--TLMPAEIPDNNNLVSP-----FLGANDTDIFGWCVICDGVFVDKASNAESRI 702

Query: 710 ---SFLAEVGDCLYLIGSAYILCWCLLQQLLQQP--INSGPILLLLLQILAIL---CLSS 761
              + + ++  C Y       L   L+  +L +    +S  +    L          + S
Sbjct: 703 AFVTSVHKLVSCRYEAVFYSALAVVLMAWILFENASHHSSKVKESSLSENNTEEHITIGS 762

Query: 762 --SDFQVNEWVEITALYYMGMAGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMFMI 819
                Q+++         +     F  GN  ++A+ +++  +  I+  S  L   L+   
Sbjct: 763 DERYLQLSDVRIPLVFMVLFNVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFK 822

Query: 820 TYASPML 826
            +   ML
Sbjct: 823 LFIPFML 829
>gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melanogaster]
          Length = 1077

 Score =  434 bits (1107), Expect = e-120
 Identities = 139/583 (23%), Positives = 229/583 (38%), Gaps = 58/583 (9%)

Query: 11  LTIFTVAGILLQII--GLSIFVFGFFPVKPTLSGVSGSESYRDPFCDS------------ 56
           LT   V   L  +I  G+ +F  GF   + + +  S                        
Sbjct: 3   LTYLFVLIWLAFLISSGVMLFSRGFLLARVSKTETSTCRRLSTNPNAEYVLTDEVVNEIF 62

Query: 57  SLISNESELHHPEKLRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANG--DA 114
             ++  S L  P+K +++  V+D L  EF L +         +  +   Q LL      A
Sbjct: 63  KDVNASSNLCLPQKSKVIVLVVDALKYEFGLYRANATDPLPYENKLVVLQELLQQNPDHA 122

Query: 115 IGYHAKAAPPTVTMPRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLG 174
                +A PPT T+ RLK + +G++  F+D+  NF +  + +DNI+ Q  +    +V LG
Sbjct: 123 RLMRFRADPPTTTLQRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQIVKNDLPVVFLG 182

Query: 175 DETWLKLFPGLFMRHDGVSSFFVKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVG 234
           D TW  L+P  F R     SF + D   VD  + +HLP EL S DW +L+ H+LG+DH G
Sbjct: 183 DSTWTDLYPHRFKRSYSYPSFDIFDLDSVDNEILKHLPKELESKDWQVLVAHFLGVDHCG 242

Query: 235 HTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSY 294
           H  G     M  KL EM++++R++              T L+++ DHGMT +G+HGG + 
Sbjct: 243 HKHGPMHEEMARKLGEMNEVIRSVVAAM-------DNDTTLLVMGDHGMTASGDHGGDTD 295

Query: 295 EETDSLMLFIGLNSNISDYASATNNV-AFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCS 353
           +ET++L+             S +++    Q+DL PTLA + GVPIP +N+G++    +  
Sbjct: 296 DETNALLFAYSKQHRFYGNDSGSDSEMLQQIDLVPTLATILGVPIPYSNLGLVNFNIVPD 355

Query: 354 LRD--FEQLRALELNSWQLLRLMLAQIQSS--SFPRVSCNCFLDGTCEGLDLDISECSGD 409
           LR     + + L L+SWQ  + +            R      +D   E   + ++     
Sbjct: 356 LRVPHLNKFQTLLLHSWQNAQQIYRYFFQYALENKRTFNVEQMD-HLETEFILLTHRVQT 414

Query: 410 K------EKQLICLFRNAAALHGIWKSKKSTESSSTMEDFSRALDAYNTFLKTAS----- 458
                  +  +  L  N   + G  +        + M            F+         
Sbjct: 415 VYNEVAFKSFVRDLNTNLRDILGTCREIWVRFDPTQMSQGLLFTFLPLFFIFLVVNNSRP 474

Query: 459 -----EWLASKTTEKPVLLLGLGVSA---MLLSCFIC----GTVFLSLFKEVYHEPKDRV 506
                 + A +     ++ L  GV          F         F ++   V        
Sbjct: 475 ADFPHIFKAKEVFYVYLINLAAGVFGYRYFKTFSFKTEEQGVIFFTAISSAVILAFHTLR 534

Query: 507 CSLSNLLNLEEVFIFALLLILVIS------MGSSSMVEEEHYI 543
              S   N   V  F  +   ++         S+S V +E  I
Sbjct: 535 HWTSIATNWSAVKRFGHMPTRLLLFGSMAVFFSNSFVIQEAKI 577
 Score = 34.6 bits (79), Expect = 6.7
 Identities = 16/56 (28%), Positives = 30/56 (53%), Gaps = 5/56 (8%)

Query: 777 YMGMAG--HFALGNSNTLATIDVAGAFIGISS---HSTILSGILMFMITYASPMLF 827
           +  +A    FA  +  TL+ I+   AF+G ++    S ++SG L+ + T+  P+ F
Sbjct: 875 WFLLAHFCFFATSHQTTLSQIEWRAAFVGRTTGIGQSNLVSGALVILNTFCGPIFF 930
>ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) biosynthesis; Gpi13p
           [Saccharomyces cerevisiae]
 pir||S64782 probable membrane protein YLL031c - yeast (Saccharomyces
           cerevisiae)
 emb|CAA97480.1| (Z73136) ORF YLL031c [Saccharomyces cerevisiae]
          Length = 1017

 Score =  428 bits (1091), Expect = e-118
 Identities = 139/599 (23%), Positives = 226/599 (37%), Gaps = 89/599 (14%)

Query: 13  IFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLR 72
           I  V   +LQ I ++ F  GF   +  L  +S                NE+    P   +
Sbjct: 37  ILLVFIAILQFISIAFFTRGFLLSRHVLDNIS--------------SQNETSKLPPRFNK 82

Query: 73  LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAI---------GYHAKAAP 123
            +  VID L  +F +       E     ++ Y  ++L+  D+               A P
Sbjct: 83  AVILVIDALRFDFAIPV----NESHSNYNLNYHNNILSLYDSFASDKDASSLLLKFIADP 138

Query: 124 PTVTMPRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFP 183
           PT T+ RLK + +G++  F+D   NF+   + +DN L Q       +   GD+TW+ LF 
Sbjct: 139 PTTTLQRLKGLTTGSLPTFIDAGSNFDGTVIEEDNFLKQLHLANKTVKFAGDDTWMALFH 198

Query: 184 GLFM-RHDGVSSFFVKDTVQVDRNVSRHLPDELNSD-DWNLLILHYLGLDHVGHTGGRNS 241
                    + S  V D   VD  V  +  D L  D +W+++I H LG+DHVGH  G + 
Sbjct: 199 PFLSNDSFPLESLNVWDLDTVDNGVMDYFHDHLQQDKEWDVMIGHMLGIDHVGHKYGPDH 258

Query: 242 PLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLM 301
             M  K  ++D  +  +              TLL+I+ DHGM   GNHGG S +E +S +
Sbjct: 259 FTMREKQIQVDQFIDWILKSI-------DDDTLLVILGDHGMDHTGNHGGDSIDELESTL 311

Query: 302 LFIG-----------LNSNISDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGT 350
                           N NI +      +   Q+DL  +LALL G PIP NN+G  +   
Sbjct: 312 FLYSKKPDMWRLKETSNYNIDNLGHDYRS-VRQIDLVSSLALLMGQPIPFNNLGWPIDEI 370

Query: 351 LCSLRDFEQLRALELNSWQLLRLMLAQIQSSSFPRVSCNCFLDGTCEGLDLDISEC--SG 408
             + R++ Q     ++  QL +  + QI              D   E L  +IS    + 
Sbjct: 371 ARNDREWSQFVNSAISQLQLYKDTM-QIHH----------GNDEILEPLAKNISNTPPTS 419

Query: 409 DKEKQLICLFRNAAALHGIWKSKKSTESSSTMEDFSRALDAYNTFLKTASEWLASKTTEK 468
           D EK +    +         +   +     ++      L      L + ++ + S    +
Sbjct: 420 DPEKFVKLGHKYQKVFLQTCEELWAKFDYYSIATGITLLATSLVLLISITKLIPSIVVNQ 479

Query: 469 PVLLLGLGVSAMLLSCFIC---------------------GTVFLSLFKEVYHEPKDRVC 507
            V     G+  M+L   +C                         + +    Y    DR  
Sbjct: 480 MVPEFVPGIIIMVLVTNLCFHGIFYVYQQPSFVDQFWGTLLATAIGIIIGCYITIFDRYN 539

Query: 508 SLSNLLNLEEV-------FIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHLLLLFKT 559
            +   + L E             ++I  +   S+S    E  I  F++STF +L L++ 
Sbjct: 540 FIWIAMRLGETLADYWSRIAVMFMIIHALLFTSNSFTIWEDRIVAFLLSTFGMLTLYEF 598
 Score =  419 bits (1066), Expect = e-115
 Identities = 139/601 (23%), Positives = 225/601 (37%), Gaps = 95/601 (15%)

Query: 17  AGIL------LQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEK 70
             IL      LQ I ++ F  GF   +  L  +S                NE+    P  
Sbjct: 35  YIILLVFIAILQFISIAFFTRGFLLSRHVLDNIS--------------SQNETSKLPPRF 80

Query: 71  LRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAI---------GYHAKA 121
            + +  VID L  +F +       E     ++ Y  ++L+  D+               A
Sbjct: 81  NKAVILVIDALRFDFAIPV----NESHSNYNLNYHNNILSLYDSFASDKDASSLLLKFIA 136

Query: 122 APPTVTMPRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKL 181
            PPT T+ RLK + +G++  F+D   NF+   + +DN L Q       +   GD+TW+ L
Sbjct: 137 DPPTTTLQRLKGLTTGSLPTFIDAGSNFDGTVIEEDNFLKQLHLANKTVKFAGDDTWMAL 196

Query: 182 FPGLFM-RHDGVSSFFVKDTVQVDRNVSRHLPDELNSD-DWNLLILHYLGLDHVGHTGGR 239
           F          + S  V D   VD  V  +  D L  D +W+++I H LG+DHVGH  G 
Sbjct: 197 FHPFLSNDSFPLESLNVWDLDTVDNGVMDYFHDHLQQDKEWDVMIGHMLGIDHVGHKYGP 256

Query: 240 NSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDS 299
           +   M  K  ++D  +  +              TLL+I+ DHGM   GNHGG S +E +S
Sbjct: 257 DHFTMREKQIQVDQFIDWILKSI-------DDDTLLVILGDHGMDHTGNHGGDSIDELES 309

Query: 300 LMLFIG-----------LNSNISDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVP 348
            +                N NI +      +   Q+DL  +LALL G PIP NN+G  + 
Sbjct: 310 TLFLYSKKPDMWRLKETSNYNIDNLGHDYRS-VRQIDLVSSLALLMGQPIPFNNLGWPID 368

Query: 349 GTLCSLRDFEQLRALELNSWQLLRLMLAQIQSSSFPRVSCNCFLDGTCEGLDLDISEC-- 406
               + R++ Q     ++  QL +  + QI              D   E L  +IS    
Sbjct: 369 EIARNDREWSQFVNSAISQLQLYKDTM-QIHH----------GNDEILEPLAKNISNTPP 417

Query: 407 SGDKEKQLICLFRNAAALHGIWKSKKSTESSSTMEDFSRALDAYNTFLKTASEWLASKTT 466
           + D EK +    +         +   +     ++      L      L + ++ + S   
Sbjct: 418 TSDPEKFVKLGHKYQKVFLQTCEELWAKFDYYSIATGITLLATSLVLLISITKLIPSIVV 477

Query: 467 EKPVLLLGLGVSAMLLSCFIC---------------------GTVFLSLFKEVYHEPKDR 505
            + V     G+  M+L   +C                         + +    Y    DR
Sbjct: 478 NQMVPEFVPGIIIMVLVTNLCFHGIFYVYQQPSFVDQFWGTLLATAIGIIIGCYITIFDR 537

Query: 506 VCSLSNLLNLEEV-------FIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHLLLLFK 558
              +   + L E             ++I  +   S+S    E  I  F++STF +L L++
Sbjct: 538 YNFIWIAMRLGETLADYWSRIAVMFMIIHALLFTSNSFTIWEDRIVAFLLSTFGMLTLYE 597

Query: 559 T 559
            
Sbjct: 598 F 598
 Score = 42.0 bits (98), Expect = 0.041
 Identities = 51/406 (12%), Positives = 102/406 (24%), Gaps = 109/406 (26%)

Query: 492 LSLFKEVYHEPKDRVCSLSNLLNLEEVFIFALLLILVISMGSSSMVEEEHYIWHFMVSTF 551
           ++                              ++I  +   S+S    E  I  F++STF
Sbjct: 558 IA---------------------------VMFMIIHALLFTSNSFTIWEDRIVAFLLSTF 590

Query: 552 HLLLLFKTA--------------------------------KSFKISKGMNILRDF---- 575
            +L L++                                   ++        L       
Sbjct: 591 GMLTLYEFVFLPKRQSTTALLTATISEKEGTTSGVNPSTANSNYLPLTRFARLLGGYHSA 650

Query: 576 ---KFGSIFSLLISGRLLR--------------GWHQGGVNWTYLPDI-----SKWLVQG 613
               F  + S++   R  +               W   G+ +  +  +       + +  
Sbjct: 651 VLIIFTRLASMITICREEQGEYCIPTFNNQNNSSWWVLGLCFLMIFILPACITGYYNLTS 710

Query: 614 GSGYVKWIQLISIILVIGLGLYTLFRTGSNRKGVRILAFGFS--TCGFLVLLHVGRYQDE 671
                  I +   +  I    +  +   S      ++A  F      F   L   R    
Sbjct: 711 SYQAAAPIWINVFLKGILGLNFVYWSLTSLENNSAVIAIPFLRDVTIFKFTL--ARIIAG 768

Query: 672 LSTGFGATVTVKVIYYLLSISSIGASLVLPWSALNKD-KSFLAEVGDC--LYLIGSAYIL 728
            S              L+    I        +  N D KS  A +     +Y      ++
Sbjct: 769 FSLIASNVGW------LMGPLCI------KLNIHNTDVKSHEATILGYTNIYGSEFFLLV 816

Query: 729 CWCLLQQLLQQPINSGPILLLLLQILAILCLSSSDF--QVNEWVEITALYYMGMAGHFAL 786
              L+  LL        +   L+    +  L   D        +   AL  +     F  
Sbjct: 817 INVLISILLF-NKPLAQLSYFLMCNQLLSILEIIDLLKLKENIIGPIALGLLSYQHFFTT 875

Query: 787 GNSNTLATIDVAGAF-IGISSHSTILSGILMFMITYASPMLFLLSL 831
           G+  T+ ++     F +           I + + T+   +L  LS+
Sbjct: 876 GHQATIPSVQWDIGFMLSEKVTFPFTQ-IAIILNTFGPHILVSLSV 920
>dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [Mus musculus]
          Length = 391

 Score =  417 bits (1063), Expect = e-115
 Identities = 85/418 (20%), Positives = 153/418 (36%), Gaps = 68/418 (16%)

Query: 13  IFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLR 72
           +F   G+L+  +  +  +F  +   P + G++                  + L  P K R
Sbjct: 3   LFFALGLLIHFVFFA-SIFDIYFTSPLVHGMTPQ---------------FTPLPPPAK-R 45

Query: 73  LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLK 132
           L+  V DGL A+ +   D            P+ ++++ + +     +    PT + P   
Sbjct: 46  LVLFVADGLRADTLYELDEDGN-----SRAPFIRNVIMH-EGSWGVSHTRVPTESRPGHV 99

Query: 133 AMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFM----R 188
           A+++G       VA  +    +  D++  +           G    L +F          
Sbjct: 100 ALIAGFYEDVSAVAKGWKENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVY 155

Query: 189 HDGVSS----FFVKDTVQVDRNVSRHLPDELN------------SDDWNLLILHYLGLDH 232
                +    F   D  ++D  V   + D  +            +++  +  LH LG+D 
Sbjct: 156 TYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDT 215

Query: 233 VGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGS 292
            GH    +S      +K++DD V+ +          D G+T  I  SDHGMT+ G+HG  
Sbjct: 216 NGHAHRPSSREYKDNIKKVDDGVKEIV-SIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAG 274

Query: 293 SYEETDSLMLFIGLNSNISDYASAT----------------NNVAFQVDLAPTLALLFGV 336
              ET +  +  G         SA                      Q D+AP +A L GV
Sbjct: 275 HPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGV 334

Query: 337 PIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLRL---MLAQIQSSSFPRVSCNCF 391
           P P N+VG+L  G L +     +  ++  N+ Q+L      + Q + ++ P +     
Sbjct: 335 PFPLNSVGILPVGYLNNTG-LFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFK 391
>ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans]
          Length = 348

 Score =  361 bits (918), Expect = 3e-98
 Identities = 82/377 (21%), Positives = 141/377 (36%), Gaps = 52/377 (13%)

Query: 14  FTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRL 73
           F +A I + ++ L   +F  +   P + G+         F +S           P K R+
Sbjct: 5   FLIASITVHLV-LIYSIFDVYYTSPLVHGI------PPQFINSQ--------EAPAK-RI 48

Query: 74  LYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLKA 133
                DGL  +               +  PY  S++     I   +++  PT + P   A
Sbjct: 49  FIISADGLRYDTF---------NKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVA 99

Query: 134 MVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPG-----LFMR 188
           + +G       VA  +    +  D++  +         M G    + LF        F  
Sbjct: 100 IFAGITEDISAVAKGWKKNPVQFDSVFNRSS----YSWMWGSPDIVNLFDDLPNAESFSY 155

Query: 189 HDGVSSFFVKDTVQVDRNVSRHLPDELN------------SDDWNLLILHYLGLDHVGHT 236
                 F  KD   +D+ V  H  + L              +  ++  LH LG+D  GH 
Sbjct: 156 SADEEDFASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHG 215

Query: 237 GGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEE 296
               S      +K +D  +  +  + ++D      +T  +  SDHGMT+ G+HG  S +E
Sbjct: 216 NKPMSRQYIDNIKVVDSGIEKV--QHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDE 273

Query: 297 TDSLMLFIGLNSNISDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRD 356
             +  +  G                 Q+DLAP ++ L G PIP N++G+L    + S   
Sbjct: 274 VLTPFVAWGAGVK--QGGPK--LDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGS 329

Query: 357 FEQLRALELNSWQLLRL 373
             + +A+E N  Q++ L
Sbjct: 330 SYEFKAIEANFKQVINL 346
>gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarrowia lipolytica]
          Length = 860

 Score =  355 bits (902), Expect = 3e-96
 Identities = 118/537 (21%), Positives = 206/537 (37%), Gaps = 84/537 (15%)

Query: 379 QSSSFPRVSCNCFLDGTCEGLDLDISECSG--DKEKQLICLFRNAAALHGIWKSKKSTES 436
           Q+   P ++    L+     L + +S+  G    E QL  L  NA  +  I + + S ES
Sbjct: 304 QTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSPEDQLNVLKNNADQMVQILQGQASRES 363

Query: 437 --------SSTMEDFSRALDAYNTFLKTASEWLASKTTEKPVLLLGLGVSAMLLSCFICG 488
                     T+       D YN FL  A  +L   ++      +  G+   LLS  +  
Sbjct: 364 DAKEVYELYDTLNSNPSVKDYYN-FLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTILAL 422

Query: 489 TVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFIFALLLILVISMGSSSMVEEEHYIWHFMV 548
           TVF +L   V                L+ +    +LL+  IS+  SS VEEEH IW+++ 
Sbjct: 423 TVFSALTLAVQG--------------LKRL-YLIILLVYFISVFGSSTVEEEHQIWYWIT 467

Query: 549 STFHLLLLFKTAKSFKISKGMNILRDFKFGSIFSLLISGRLLRGWHQGGVNWTYLPDISK 608
           S   +  L+ +    K   G N    + F  +F      R++  W+Q G  +T   DI  
Sbjct: 468 SG-WMAFLYISGSRNKFGDGFN----WMFVQVFV-----RMMISWNQTGQKFTKKDDIVT 517

Query: 609 WLVQGGSGYVKWIQLISIILVIGLGLYTLFRTGSNRKGVRI-----LAFGFSTCGFLVLL 663
           WL + G+    WI    I++  G+    ++R G ++   ++     L   F++ GF +  
Sbjct: 518 WLSKDGNQPSLWIL---ILVTYGVAFNKVWRYGFSKVESKLAFLLTLITTFASVGFKIT- 573

Query: 664 HVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVLPWSALNKDKSFLAEVGDCLYLIG 723
                    +   G  V   ++Y L+ +      +    + L +  +F       LY + 
Sbjct: 574 --------QAWEAGEVVPAPLLY-LMGLPGTLNEVNARMAGLAR-FAFSTIAAGSLYRVL 623

Query: 724 S-------------AYILCWCLLQQLLQQPINSGPILLLLLQILAILCLSSSDFQVNEWV 770
           S                L   L+ Q   Q I    +   L   L      S  F   +  
Sbjct: 624 SLAGTDKVNLIRDLHAFLTLFLITQSRIQNIPLFMVYYFLEIFLRKATNRSFIFSSRDIY 683

Query: 771 EITALYYMG------------MAGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMFM 818
           +  AL+                   F++GNSN++A+ID++ A+ G++ +     G+L F+
Sbjct: 684 QTEALFQKLVLVLSVSTLLLEQVSFFSMGNSNSMASIDLSNAYNGVTLYQIEFVGVLTFV 743

Query: 819 ITYASPMLFLLSLVMYIGANLRNHSNSTISTHRETTKARVPLPCSALHQLNTLDRIY 875
             +  P+ +  + + ++   L +H  + I          V L    + Q  TL R+Y
Sbjct: 744 SNWIGPLYWSTAGLSFL---LEDHVRNAIFAKIAEKNNDVKLTTKLVQQALTL-RVY 796
 Score =  339 bits (861), Expect = 2e-91
 Identities = 132/389 (33%), Positives = 193/389 (48%), Gaps = 51/389 (13%)

Query: 14  FTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRL 73
             V  ++LQ+  + +F  GF P +  L G + S            +S E+        + 
Sbjct: 8   LAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESR-----------VSTEAP-----FQKA 51

Query: 74  LYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLKA 133
           +  V+D   ++F             + + P     + +G AI + A + PPTVT+PR+K 
Sbjct: 52  IIMVVDAFRSDFAFSD---------QSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKG 102

Query: 134 MVSGAIGGFLDVAFNFNTQA-----LLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMR 188
           + +G+   FLD   N             D+ L Q  R G K+ M GD+TW+KLFPG+F  
Sbjct: 103 LTTGSTPNFLDAVLNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDD 162

Query: 189 HDGVSSFFVKDTVQVDRNVSRHLPDELNSD-DWNLLILHYLGLDHVGHTGGRNSPLMPAK 247
            +G +SFFV D  +VD NV+RH+  +L+   +W++LILHYLGLDH+GH  G  SP MPAK
Sbjct: 163 CEGTASFFVSDYTEVDNNVTRHIDTQLDQKTEWDVLILHYLGLDHIGHKTGPESPFMPAK 222

Query: 248 LKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLMLFIGLN 307
            KEMDDI   ++             T+LI++ DHGM E GNHGGSS  ET + M+F    
Sbjct: 223 QKEMDDIFDKLYNSC-------DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPK 275

Query: 308 SNISDY-------------ASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSL 354
              +                   ++   Q DL PTL  L G+  PKNN+GVLV   L   
Sbjct: 276 FETAQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLW 335

Query: 355 RDFEQLRALELNSWQLLRLMLAQIQSSSF 383
              +QL  L+ N+ Q+++++  Q    S 
Sbjct: 336 SPEDQLNVLKNNADQMVQILQGQASRESD 364
>dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:1351629,
           evidence:ISS~phosphatidylinositol glycan, class
           N~putative [Mus musculus]
          Length = 320

 Score =  338 bits (859), Expect = 3e-91
 Identities = 64/328 (19%), Positives = 117/328 (35%), Gaps = 48/328 (14%)

Query: 13  IFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLR 72
           +F   G+L+  +  +  +F  +   P + G++                  + L  P K R
Sbjct: 3   LFFALGLLIHFVFFA-SIFDIYFTSPLVHGMTPQ---------------FTPLPPPAK-R 45

Query: 73  LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLK 132
           L+  V DGL A+ +   D            P+ ++++ + +     +    PT + P   
Sbjct: 46  LVLFVADGLRADTLYELDEDGN-----SRAPFIRNVIMH-EGSWGVSHTRVPTESRPGHV 99

Query: 133 AMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFM----R 188
           A+++G       VA  +    +  D++  +           G    L +F          
Sbjct: 100 ALIAGFYEDVSAVAKGWKENPVESDSLFNE----RKYTWSWGSPDILPMFAKGASGDHVY 155

Query: 189 HDGVSS----FFVKDTVQVDRNVSRHLPDELN------------SDDWNLLILHYLGLDH 232
                +    F   D  ++D  V   + D  +            +++  +  LH LG+D 
Sbjct: 156 TYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDT 215

Query: 233 VGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGS 292
            GH    +S      +K++DD V+ +          D G+T  I  SDHGMT+ G+HG  
Sbjct: 216 NGHAHRPSSREYKDNIKKVDDGVKEIV-SIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAG 274

Query: 293 SYEETDSLMLFIGLNSNISDYASATNNV 320
              ET +  +  G         SA    
Sbjct: 275 HPSETLTPFVTWGAGIKFPQNVSAQQYD 302
>gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melanogaster]
          Length = 919

 Score =  327 bits (830), Expect = 7e-88
 Identities = 80/538 (14%), Positives = 163/538 (29%), Gaps = 83/538 (15%)

Query: 19  ILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRLLYQVI 78
           +++ ++ L   +  +F            +S      +      E  L  P   RL+  V+
Sbjct: 7   LVVHLLLLGSILSIYF------------QSTILSDLEPLSTLRELGLEPPA-DRLVVFVV 53

Query: 79  DGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLKAMVSGA 138
           DGL A+ VL         + +         L    A+   ++A PPTVT P   A+  G 
Sbjct: 54  DGLRAQSVLADHCSAVPDLRE---------LFVEQALVGISRACPPTVTRPGHIAIFGGF 104

Query: 139 IGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMRHDGVSSF--- 195
                             D++  +       M     + +  L  G         +F   
Sbjct: 105 NEDPAATLT---WNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGA--PLRFETFARS 159

Query: 196 FVKDTVQVDRNVSRHLPDELNSDDW---------NLLILHYLGLDHVGHTGGRNSPLMPA 246
            + D +++D+     + + + ++            +  ++   +D   H    NS     
Sbjct: 160 DISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFRE 219

Query: 247 KLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLMLFIGL 306
           KL      +R  +   + +   +  +T  ++ +D+G++    HGG      ++  +  G 
Sbjct: 220 KLNYTQRGIRQTYE--LFESVFNDSRTAYLMTADYGISL---HGGGGERGVETPFILWGA 274

Query: 307 NSNI------------SDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSL 354
                            +          Q+ LAP ++ L G+P P NN+ ++  G L   
Sbjct: 275 GVKRSAPNPGQNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLN-T 333

Query: 355 RDFEQLRALELNSWQLLRLMLAQIQSSSFPRV------SCNCFLDGTCEGLDLDISECSG 408
               +L+ L LN+ QLL      I+      +        +           +     + 
Sbjct: 334 SVQYELQVLHLNAMQLLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAK 393

Query: 409 DK-EKQLICLFRNAAALHGIWKSKKSTESSSTMEDFSRALDAYNTFLKTASEWLASKTTE 467
           ++ E+ L    + A       +          +        +Y  +       LA ++  
Sbjct: 394 EQYEEALKVSHKIAKLAQECME---YYHGYYHLPLLVATTASYLVWFYLLLVRLARES-- 448

Query: 468 KPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFIFALLL 525
                        L    +                   +  L  L  +  +  F LLL
Sbjct: 449 -NHPKSERK--GYLTWTTL---------MMCLGGLV--LLELMILQRVPHLTAFYLLL 492
>sp|Q09782|YA93_SCHPO HYPOTHETICAL 85.7 KD PROTEIN C13G6.03 IN CHROMOSOME I
 pir||S62432 major facilitator protein homolog - fission yeast
           (Schizosaccharomyces pombe)
 pir||T37638 major facilitator protein homolog - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA91096.1| (Z54308) putative major facilitator superfamily protein
           [Schizosaccharomyces pombe]
          Length = 758

 Score =  325 bits (825), Expect = 2e-87
 Identities = 142/422 (33%), Positives = 202/422 (47%), Gaps = 45/422 (10%)

Query: 14  FTVAGIL-LQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLR 72
           F   GI  LQI G  +F+ GFFP K   +G + S  +  P                   +
Sbjct: 3   FAFFGIFWLQIFGSILFLLGFFPHKNDSTGKAMSNQFSPPAVI---------------DQ 47

Query: 73  LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANG-DAIGYHAKAAPPTVTMPRL 131
           +++ ++D L A+FV  K           +MP+TQSLL N    IG+ A A  PTVTMPRL
Sbjct: 48  VVFVMVDALRADFVFSK---------SHNMPFTQSLLYNSTHGIGFSAFARSPTVTMPRL 98

Query: 132 KAMVSGAIGGFLDVAFNFNTQAL-----LDDNILGQFFRIGWKMVMLGDETWLKLFPGLF 186
           KA+ +G I GFLDV  N             D+ + Q      K+   GD+TWLKLFP  F
Sbjct: 99  KALTTGTIPGFLDVLLNIAESDTGSSIEAQDSWVYQLNSFNKKIEFYGDDTWLKLFPSAF 158

Query: 187 MRHDGVSSFFVKDTVQVDRNVSRHLPDEL---NSDDWNLLILHYLGLDHVGHTGGRNSPL 243
            + +G +SFFV D  +VD NV+R+    L    S  W+ LILHYLG+DH+GH  G +SPL
Sbjct: 159 SKFEGTTSFFVSDYTEVDNNVTRNFDHALPSSLSHSWDALILHYLGVDHIGHLYGPSSPL 218

Query: 244 MPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLM-L 302
           +  KL E+D I+  ++             +L+++  DHGM E GNHGGSS  ET + + L
Sbjct: 219 LNIKLLEIDTIISRIYKYLQEYDEKTNTHSLIVLCGDHGMNEVGNHGGSSSGETTAALSL 278

Query: 303 FIGLNS---------NISDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCS 353
               N          N+ D   +      QVD+ PT+ LL G+PIPK N+G ++      
Sbjct: 279 LFPSNELSHINKPILNMDDNPYSILERVEQVDVVPTICLLLGIPIPKGNMGKVLSPVTEL 338

Query: 354 LRDFEQLR-ALELNSWQLLRLMLAQIQSSSFPRVSCNCFLDGTCEGLDLDISECSGDKEK 412
            +D +  + A   N +QL  L    + +S       +  L+     L+   S+       
Sbjct: 339 WKDTKTAKMAALSNLFQLSLLKNPSLTTSELSTQFQDSDLNDIRLALENLQSQMVAQSSS 398

Query: 413 QL 414
             
Sbjct: 399 YS 400
 Score =  249 bits (630), Expect = 2e-64
 Identities = 90/461 (19%), Positives = 163/461 (34%), Gaps = 85/461 (18%)

Query: 379 QSSSFPRVSCNCFLDGTCEGLDLDIS---ECSGDKEKQLICLFRNAAALHGIWKSKKSTE 435
           Q    P +     +      +   +S   E   D +   +    N   L  + K+   T 
Sbjct: 308 QVDVVPTICLLLGIPIPKGNMGKVLSPVTELWKDTKTAKMAALSNLFQL-SLLKNPSLTT 366

Query: 436 SSSTMEDFSRALDAYNTFLKTASEWLASKTTEKPVLLLGLGVSAMLLSCFICGTVFLSLF 495
           S  + +     L+     L+     + ++++   +  + + +S +     +   +F    
Sbjct: 367 SELSTQFQDSDLNDIRLALENLQSQMVAQSSSYSLDRMLVAISILGACSILSLILF---- 422

Query: 496 KEVYHEPKDRVCSLSNLLNLEEVFIFALLLIL-VISMGSSSMVEEEHYIWHFMVSTFHLL 554
                          NL N +E+  FA  ++  +I + SSS +EEEH IW+F   +  LL
Sbjct: 423 --------------RNLYNYKELLAFAPFVVQNIIIVFSSSFIEEEHVIWYFAAVSLSLL 468

Query: 555 LLFKTAKSFKISKGMNILRDFKFGSIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQGG 614
            L         S             +F L I  R    W+Q G  ++ L DI        
Sbjct: 469 QLLNPKTRLAGS-----------LQLFCLSIIKR----WNQTGQKYSDLRDIV------- 506

Query: 615 SGYVKWIQLISIILVIGLGLYTLFRTGSNRKGVRILAFGFSTCGFLVLLHVGRYQDELST 674
                +I   + +  I            +   +  L+  F    + ++  + ++ +EL  
Sbjct: 507 ---DDFIAPSTFMKTILCVTSAFMPAIRSPSPINFLSSMFIAF-YKLMPIISKHLNELPI 562

Query: 675 G--FGATVTVKVIYYLLSISSIGASLVLPWSALNKDKSFLAEVGDCLYLIGSAYILCWCL 732
              F  T  V++I+ LL IS                K    ++   L            L
Sbjct: 563 IASFDYTFFVRIIWSLLLISF-------------LSKPTFKQLRCQL-----------SL 598

Query: 733 LQQLLQQPINSGPILLLLLQILAILCLSSSDFQVNEWVEITALYYMG-MAGHFALGNSNT 791
              LL +  N G  LL  +                E    + +YY+      F+LGNSN+
Sbjct: 599 FILLLTRLENMGLYLLYDIWQRT---------MPEEGTLASVMYYVAEQVAFFSLGNSNS 649

Query: 792 LATIDVAGAFIGISSHSTILSGILMFMITYASPMLFLLSLV 832
           LAT+D++ A+ G+ S++    GIL+F   +A  + + L   
Sbjct: 650 LATVDLSQAYTGLDSYNIFAVGILLFTSVFAGALWWCLHQP 690
>ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involved in the attachment
           of glycosylphosphatidylinositol (GPI) anchors to
           proteins.; Las21p [Saccharomyces cerevisiae]
 sp|P40367|YJG2_YEAST HYPOTHETICAL 94.9 KD PROTEIN IN MRPL8-NUP82 INTERGENIC REGION
 pir||S50810 probable membrane protein YJL062w - yeast (Saccharomyces
           cerevisiae)
 emb|CAA84061.1| (Z34288) HRC830 [Saccharomyces cerevisiae]
 emb|CAA89353.1| (Z49337) ORF YJL062w [Saccharomyces cerevisiae]
          Length = 830

 Score =  319 bits (811), Expect = 1e-85
 Identities = 152/574 (26%), Positives = 242/574 (41%), Gaps = 119/574 (20%)

Query: 11  LTIFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEK 70
           L  FT      Q++ + +F+F FFP K  L+G+S  +   D   D   +  +        
Sbjct: 3   LKQFTCLSCA-QLLAILLFIFAFFPRKIVLTGIS--KQDPDQDRD---LQRDRP-----F 51

Query: 71  LRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPR 130
            +L++ +ID L ++F+                      L  G+A GY + A PPTVT+PR
Sbjct: 52  QKLVFVIIDALRSDFLFDSQISHF--------NNVHQWLNTGEAWGYTSFANPPTVTLPR 103

Query: 131 LKAMVSGAIGGFLDVAFN----FNTQALLD-DNILGQFFRIGWKMVMLGDETWLKLFPGL 185
           LK++ +G+   F+D+  N     ++  L + D+ L QF +    +  +GD+TWLKLFP  
Sbjct: 104 LKSITTGSTPSFIDLLLNVAQDIDSNDLSEHDSWLQQFIQHNNTIRFMGDDTWLKLFPQQ 163

Query: 186 FMRH-DGVSSFFVKDTVQVDRNVSRHLPDELNSD--DWNLLILHYLGLDHVGHTGGRNSP 242
           +    D   SFFV D  QVD NV+R+LP +L  +   W++ ILHYLGLDH+GH  G +S 
Sbjct: 164 WFDFADPTHSFFVSDFTQVDNNVTRNLPGKLFQEWAQWDVAILHYLGLDHIGHKDGPHSK 223

Query: 243 LMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLML 302
            M AK +EMD I+++++    +    D   TL+ ++ DHGM E GNHGGSS  ET + +L
Sbjct: 224 FMAAKHQEMDSILKSIYD--EVLEHEDDDDTLICVLGDHGMNELGNHGGSSAGETSAGLL 281

Query: 303 FIGL------------NSNISDYAS-----ATNNVAFQVDLAPTLALLFGVPIPKNNVGV 345
           F+              N  +   AS            Q+D+ PT+A LFG+PIP N+VG+
Sbjct: 282 FLSPKLAQFARPESQVNYTLPINASPDWNFQYLETVQQIDIVPTIAALFGMPIPMNSVGI 341

Query: 346 LVPGTLCSLRDFEQLRALELNSWQLLRLMLAQIQSSSFPRVSCNCFLDGTCEGLDLDISE 405
           ++P  L  L    +L +++ N   L +L               +   +     +      
Sbjct: 342 IIPDFLQLLP--NKLASMKENFMHLWKL---SDHHGEVAL--DDFTAEDIYTKMYTIQET 394

Query: 406 CSGDKEKQLICLFRNAAALHGIWKSKKSTESSSTMEDFSRALDAYNTFLKTASEWLASKT 465
            +                             +  +   +       T             
Sbjct: 395 LTKSATNY-----------------------NYPLLTLAFVGFLIIT------------- 418

Query: 466 TEKPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFIFALLL 525
                               I   V L      Y  P            +  + +  + +
Sbjct: 419 -------------------IIAIYVLLR-----YSGPDFWQL------RVSSLSVLLVSI 448

Query: 526 ILVISMGSSSMVEEEHYIWHFMVSTFHLLLLFKT 559
           IL +S  +SS +EEEH +W ++V+ F  + LF  
Sbjct: 449 ILGVSTFASSFIEEEHQLWWWIVTAFSAVPLFVY 482
 Score =  294 bits (747), Expect = 3e-78
 Identities = 95/512 (18%), Positives = 174/512 (33%), Gaps = 75/512 (14%)

Query: 346 LVPGTLCSLRDFEQL-RALELNSWQLLR-LMLAQIQS-SSFPRVSCNCFLDGTCEGLDLD 402
           L P      R   Q+   L +N+        L  +Q     P ++    +      + + 
Sbjct: 283 LSPKLAQFARPESQVNYTLPINASPDWNFQYLETVQQIDIVPTIAALFGMPIPMNSVGII 342

Query: 403 ISECSGDKEKQLICLFRNAAALHGIWKSKKSTESSSTMEDFSRALDAYNTFLKTASEWLA 462
           I +       +L  +  N      +WK          ++DF  A D Y T + T  E L 
Sbjct: 343 IPDFLQLLPNKLASMKEN---FMHLWK-LSDHHGEVALDDF-TAEDIY-TKMYTIQETLT 396

Query: 463 SKTTEKPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFIFA 522
              T     LL L     L+   I   V L      Y  P            +  + +  
Sbjct: 397 KSATNYNYPLLTLAFVGFLIITIIAIYVLLR-----YSGPDFWQL------RVSSLSVLL 445

Query: 523 LLLILVISMGSSSMVEEEHYIWHFMVSTFHLLLLFKTAKSFKISKGMNILRDFKFGSIFS 582
           + +IL +S  +SS +EEEH +W ++V+ F  + LF              L        F 
Sbjct: 446 VSIILGVSTFASSFIEEEHQLWWWIVTAFSAVPLFVY-----------RLNVLIIVRWFI 494

Query: 583 LLISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLISIILVIGLGLYTLFRTGS 642
           ++   R ++ W+  G  + Y   +S  L Q  S       L  ++L++    + +     
Sbjct: 495 MMACVRSIKFWNNSGQKFIYSNVMSNLLNQNPSWKWCLNMLTFLVLIMASAGFQVLHFI- 553

Query: 643 NRKGVRILAFGFSTCGFLVLLHVG--------RYQDEL-------STGFGATVTVKVIYY 687
                 ++   F+   + +   +          +  +L        T     V  +V + 
Sbjct: 554 --VTTILVGLCFT---YKISWEIVNGNQAEIPLFMHDLLAKIDFAPTESNLIVLARVFFQ 608

Query: 688 LLSISSIGASLVLPWSALNKDKSFLAEVGDCLYLIGSAYILCWCLLQQLLQQPINSGPIL 747
             +I  I   ++     LNK+           YLI    +    +   L+ Q  +     
Sbjct: 609 AWAIVVISRLVLTKLKVLNKN-----------YLIKDMKVY---ITILLMFQTSSQNIGQ 654

Query: 748 LLLLQILAILCLSSSDFQVNEWVEITALYYM-------GMAGHFAL-GNSNTLATIDVAG 799
            L+ QIL               +  T+  Y             F   G +N+++TID+  
Sbjct: 655 FLVFQILESQIFYFFQNIPTASLTSTSKIYFSNLVSLILQNFTFFQFGGTNSISTIDLGN 714

Query: 800 AFIGISS-HSTILSGILMFMITYASPMLFLLS 830
           A+ G+SS ++  + GILM +  +A  + + + 
Sbjct: 715 AYHGVSSDYNIYVVGILMSVANFAPAIYWSML 746
>gb|AAL39196.1| (AY069051) GH05767p [Drosophila melanogaster]
          Length = 608

 Score =  292 bits (741), Expect = 2e-77
 Identities = 100/553 (18%), Positives = 182/553 (32%), Gaps = 88/553 (15%)

Query: 350 TLCSLRDFEQLRALELNSWQLLRLMLAQIQSSSFPRVS-CNCFLDGTCEGLDLDISECSG 408
            L SL    QL A   N+  LL     +       R      + + T     L      G
Sbjct: 1   MLQSLSLEHQLYAYFYNAHHLLNKARVKFGHEIVHRSDYYTWYQNATLLHKKLLRPLREG 60

Query: 409 DKEKQLICLFRNAA--------ALHGIWKSKKSTESS----------STMEDFSRALDAY 450
           D        ++NA          +  +                    ++          Y
Sbjct: 61  DGGGASQVYYQNAKLNYMRVAREISDLLSESLVKFDYGFIAVGLALTTSTSLHIVISVLY 120

Query: 451 N---------------TFLKTA----------SEWLASKTTEKPVLLLGLGVSAMLLSCF 485
                            +L             +  +   ++    +LL + +S    + +
Sbjct: 121 LDLTEQLQLDGLKVGQLWLSVIAAVVLNYTSHALDIIMTSSTLYSILLLVPISI---AVY 177

Query: 486 ICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFIFALLLILVISMGSSSMVEEEHYIWH 545
           +   V  +L K        R   +S  L L    + A   I  +++GSSS +E E+  W+
Sbjct: 178 LTIDVAQALLKIALPPLYTRRLKISIPLPLP---LLACYAIRTLTLGSSSFIEFEYNTWY 234

Query: 546 FMVSTFHLLLLFKTAKSFKISKGMNILRDFKFGSIFSLLISGRLLRGWHQGGVNWTYLPD 605
           ++ +T  LL  F+T               ++       L +GR L       + W     
Sbjct: 235 YLGNTLILLTAFRT-------------LRWRITKTNVEL-NGRHLYTIASTCL-WQMRKV 279

Query: 606 ISKWLVQGGSGYVKWIQLI---SIILVIGLGLYTLFRTGSNRKGVRILAFGFSTCGFLVL 662
           +   ++     Y+  +Q I    +I  + L    L R     + +   A  F    F  L
Sbjct: 280 LVVLMLLTLMRYIHRLQAIRSTVVIFSMLLLWARLHRHSQLPQSLASGAALFMVYCFRGL 339

Query: 663 LHVGRYQDELSTGFGATVTVKVIYY---LLSISSIGASLVLPWSALNKDKSFLAEVGDCL 719
                + D  S      +   ++ +   L  +  +G    LP          +   G  L
Sbjct: 340 NGQVLFFDVPSHMAAKLMVPTLVIFWCCLALVLMLGYRAALPQ---AHSFGKVPPTG-AL 395

Query: 720 YLIGSAYILCWCLLQQLLQQPINS--GPILLLLLQILAILC--------LSSSDFQVNEW 769
             +    +    LL  LLQ+  N    P+LL+ LQ    LC          S        
Sbjct: 396 LQLLQTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVYGTSARKFSVRLV--HV 453

Query: 770 VEITALYYMGMAGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMFMITYASPM-LFL 828
            +I    ++     F  GNSN+L+TID+   +IG ++++  +  I + + TY++ +  FL
Sbjct: 454 YKIIMTIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIFVTLNTYSADIHAFL 513

Query: 829 LSLVMYIGANLRN 841
             +V  + ++LR+
Sbjct: 514 YLVVHTLRSDLRS 526
 Score =  261 bits (662), Expect = 4e-68
 Identities = 101/503 (20%), Positives = 183/503 (36%), Gaps = 69/503 (13%)

Query: 361 RALELNSWQLLRLMLAQIQSSSFPR---VSCNCFLDGTCEGLDLDISECSGDKEKQLICL 417
           +  +LN  ++ R +   +  S                T   L + IS    D  +QL   
Sbjct: 71  QNAKLNYMRVAREISDLLSESLVKFDYGFIAVGLALTTSTSLHIVISVLYLDLTEQL--- 127

Query: 418 FRNAAALHGIWKSK--KSTESSSTMEDFSRALDAYNTFLKTASEWLASKTTEKPVLLLGL 475
                 L G+   +   S  ++  +   S ALD   T            ++    +LL +
Sbjct: 128 -----QLDGLKVGQLWLSVIAAVVLNYTSHALDIIMT------------SSTLYSILLLV 170

Query: 476 GVSAMLLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFIFALLLILVISMGSSS 535
            +S    + ++   V  +L K        R   +S  L L    + A   I  +++GSSS
Sbjct: 171 PISI---AVYLTIDVAQALLKIALPPLYTRRLKISIPLPLP---LLACYAIRTLTLGSSS 224

Query: 536 MVEEEHYIWHFMVSTFHLLLLFKTAKSFKISKGMNILRDFKFGSIFSLLISGRLLRGWHQ 595
            +E E+  W+++ +T  LL  F+T               ++       L +GR L     
Sbjct: 225 FIEFEYNTWYYLGNTLILLTAFRT-------------LRWRITKTNVEL-NGRHLYTIAS 270

Query: 596 GGVNWTYLPDISKWLVQGGSGYVKWIQLI---SIILVIGLGLYTLFRTGSNRKGVRILAF 652
             + W     +   ++     Y+  +Q I    +I  + L    L R     + +   A 
Sbjct: 271 TCL-WQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLLLWARLHRHSQLPQSLASGAA 329

Query: 653 GFSTCGFLVLLHVGRYQDELSTGFGATVTVKVIYY---LLSISSIGASLVLPWSALNKDK 709
            F    F  L     + D  S      +   ++ +   L  +  +G    LP        
Sbjct: 330 LFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFWCCLALVLMLGYRAALPQ---AHSF 386

Query: 710 SFLAEVGDCLYLIGSAYILCWCLLQQLLQQPINS--GPILLLLLQILAILC--------L 759
             +   G  L  +    +    LL  LLQ+  N    P+LL+ LQ    LC         
Sbjct: 387 GKVPPTG-ALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVYGTSARK 445

Query: 760 SSSDFQVNEWVEITALYYMGMAGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMFMI 819
            S         +I    ++     F  GNSN+L+TID+   +IG ++++  +  I + + 
Sbjct: 446 FSVRLV--HVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIFVTLN 503

Query: 820 TYASPM-LFLLSLVMYIGANLRN 841
           TY++ +  FL  +V  + ++LR+
Sbjct: 504 TYSADIHAFLYLVVHTLRSDLRS 526
>ref|NP_495820.1| (NM_063419) Yeast YJ10 like [Caenorhabditis elegans]
 pir||T21487 hypothetical protein F28C6.4 - Caenorhabditis elegans
 emb|CAA92675.1| (Z68315) Similarity to Yeast hypothetical protein YJ10
           (SW:YJ10_YEAST)~cDNA EST yk160e12.5 comes from this
           gene~cDNA EST yk160e12.3 comes from this gene~cDNA EST
           yk317h4.3 comes from this gene~cDNA EST yk317h4.5 comes
           from this gene [Caenorhabditis ele>
          Length = 795

 Score =  292 bits (740), Expect = 2e-77
 Identities = 112/434 (25%), Positives = 186/434 (42%), Gaps = 41/434 (9%)

Query: 18  GILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRLLYQV 77
            +++    L ++ F               +    P  +      +         RL++ V
Sbjct: 63  VLVVCACALLVYSFVAL------------DITPTPPTEEFGFK-DGNQESSSSPRLVFMV 109

Query: 78  IDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLKAMVSG 137
           ID     F+            K  M +T+S +    A  + A A  PTVT+PR+ A ++G
Sbjct: 110 IDAFRLSFLTSS---------KSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTG 160

Query: 138 AIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMRHDGVSSFFV 197
            +  F  V  N  T  +   N + +  +IG K+   GD+TW++L P  F + +GV+SFFV
Sbjct: 161 TLPSFGTVLTNLATAEMKTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFV 220

Query: 198 KDTVQVDRNVSRHLPDEL--NSDDWNLLILHYLGLDHVGHTGGRNSPLMPAKLKEMDDIV 255
            D   VD NV+RHL  EL   +  W+ LILHYLGLDH+GH+ G +S  +P KLKEMDD++
Sbjct: 221 SDYTDVDNNVTRHLDTELSNTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVI 280

Query: 256 RTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLMLFI--GLNSNISDY 313
             +H       +    ++ LI+  DHGMT  G+HGG+S +ET   ++    G      +Y
Sbjct: 281 GRIHKYLKS-STSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKNY 339

Query: 314 ASATNN-----VAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRDFEQLRALELNSW 368
            +  ++        Q+D++ T+  +F +PIP  + G+ +        +            
Sbjct: 340 GNQDDSLKQPPRIEQIDVSSTIFDVFNMPIPIESYGISLINYFSDDEEEY-FEKQHNQFR 398

Query: 369 QLLRLMLAQIQS--SSFPRVSCNCFLDGTCEGLDLDISECSGDK-----EKQLICLFRNA 421
           ++++     I          S         +      SE  G       +   +C+F   
Sbjct: 399 RIVQAKHLAISDICDENCDYSDKFIKSALKKWFLTVQSELIGSASEVPNKSLGVCVFLLL 458

Query: 422 AALHGIWKSKKSTE 435
            AL  +     +  
Sbjct: 459 VAL-TLSMGLWNLH 471
 Score =  264 bits (669), Expect = 5e-69
 Identities = 84/455 (18%), Positives = 154/455 (33%), Gaps = 91/455 (20%)

Query: 384 PRVSCNCFLDGTCEGLDL-DISECSGDKEKQLICLFRNAAALHGIWKSKKSTESSSTMED 442
             +     +    E   +  I+  S D+E+      +       I ++K    S    E+
Sbjct: 359 STIFDVFNMPIPIESYGISLINYFSDDEEEYF---EKQHNQFRRIVQAKHLAISDICDEN 415

Query: 443 FSRALDAYNT----FLKTASEWLASKTTEKPVLLLGLGVSAMLLSCFICGTVFLSLFKEV 498
              +     +    +  T    L    +E  V    LGV   LL   +  ++        
Sbjct: 416 CDYSDKFIKSALKKWFLTVQSELIGSASE--VPNKSLGVCVFLLLVALTLSM-------- 465

Query: 499 YHEPKDRVCSLSNLLNLEEVFIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHLLLLFK 558
                +   S S+         F + LI  I+  +SS++EEEH IW+++ ST   +   +
Sbjct: 466 --GLWNLHLSKSD---------FFIFLIN-ITYFASSLIEEEHEIWYYLGSTVVAIRALR 513

Query: 559 TAKSFKISKGMNILRDFKFGSIFSLLISGRLLRGWHQ-GGVNWTYLPDISKWLVQGGSGY 617
                       I    +  SIF L    R+   + Q     W     +    +   +  
Sbjct: 514 ---------NFKIWNKTEVKSIFFLAFLHRIACSYTQSTRRRWIMDSSLLPPSIFSDTLD 564

Query: 618 VKWIQLISIILVIGLGLYTLFRTGSNRKGVRILAFGFSTCGFLVLLHVGRYQDELSTGFG 677
            +   L +I+                   V +    F   G+       ++         
Sbjct: 565 FQPNNLNTILNEY-------------PIIVILTCSLFWMYGYK----QSKF--------- 598

Query: 678 ATVTVKVIYYLLSISSIGASLVL----PWSALNKDKSFLAEVGDCLYLIGSAYILCWCLL 733
             +   V ++L        + VL      S L    S  + +  CL L+ +   +   LL
Sbjct: 599 HIILPMVSHFLRLFELTQFNEVLMHFIRLSILPISYSTGSVLAGCLPLLLAIVPVSQILL 658

Query: 734 QQLLQQPINSGPILLLLLQILAILCLSSSDFQVNEWVEITALYYMGMAGHFALGNSNTLA 793
             ++          L        L L S +F             + M+  F  GNSN+L+
Sbjct: 659 LLVIY-----NMGKLFS-----KLNLGSVEFVT-----------LCMSSFFYTGNSNSLS 697

Query: 794 TIDVAGAFIGISSHSTILSGILMFMITYASPMLFL 828
           T+ +  A++G+SS+  IL G+ + + T++ P+LFL
Sbjct: 698 TLSLTSAYVGLSSYQPILVGLQLMLYTFSGPILFL 732
>ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thaliana]
 dbj|BAB10512.1| (AB005238) gene_id:MKP11.10~unknown protein [Arabidopsis thaliana]
          Length = 884

 Score =  280 bits (710), Expect = 7e-74
 Identities = 87/312 (27%), Positives = 138/312 (43%), Gaps = 31/312 (9%)

Query: 12  TIFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKL 71
            +  +  +L+  I + IF  GF   +  L   S            S +S    L  P   
Sbjct: 9   KLTALGFLLIHAIAILIFTRGFLLTRTELPFHSTC----------SDVSLSPCLASPRSN 58

Query: 72  RLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGD--AIGYHAKAAPPTVTMP 129
                             D     K   + +   Q+L    D  A  + A A PPT ++ 
Sbjct: 59  H-----------------DSSSEPKPWMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQ 101

Query: 130 RLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMRH 189
           RLK + +G +  F+D+  +F   A+++DN + Q    G ++VM+GD+TW +LFP  F + 
Sbjct: 102 RLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKS 161

Query: 190 DGVSSFFVKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVGHTGGRNSPLMPAKLK 249
               SF VKD   VD     HL   L  DDW++LI H+LG+DH GH  G +S  M  KL+
Sbjct: 162 YPFPSFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLE 221

Query: 250 EMDDIVRTMHLRAMMDR--SHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLMLFIGLN 307
           + + ++  +                T+LI++ DHG T NG+HGG + EE ++ M  +   
Sbjct: 222 QYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTK 281

Query: 308 SNISDYASATNN 319
            + +      + 
Sbjct: 282 KHTTLVPPEFDT 293
 Score = 40.4 bits (94), Expect = 0.14
 Identities = 26/131 (19%), Positives = 47/131 (35%), Gaps = 11/131 (8%)

Query: 450 YNTFLKTASEWLASKTTEKPVLLLGLGVSAMLLSCFIC-GTVFLSLFKEVYHEPKDRVCS 508
           Y  F  +  E   SK TE  + L+  G   +++S  +    VF                 
Sbjct: 444 YLNFFSSVVELARSKWTEFNLNLMITGFGILVISLILQFLAVFHGDKSYAVGS------- 496

Query: 509 LSNLLNLEEVFIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHLLLLFKTAKSFKISKG 568
               L+    F   ++ I   S  S+S + EE  + +F+++T  L+ L  +     + K 
Sbjct: 497 ---WLSTGAAFTLFIVTIRACSFLSNSYILEEGKVANFLLATTGLIKLRYSVMRKTMRKE 553

Query: 569 MNILRDFKFGS 579
             +     F  
Sbjct: 554 AFMFLAMVFVL 564
>dbj|BAB17014.1| (AB050262) hypothetical protein [Macaca fascicularis]
          Length = 333

 Score =  255 bits (647), Expect = 2e-66
 Identities = 83/310 (26%), Positives = 130/310 (41%), Gaps = 16/310 (5%)

Query: 222 LLILHYLGLDHVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDH 281
           +LILHYLGLDH+GH  G NSPL+  KL EMD ++  +H              LL++  DH
Sbjct: 1   MLILHYLGLDHIGHISGPNSPLIGHKLSEMDSVLMKIHTSLQSKERETPLPNLLVLCGDH 60

Query: 282 GMTENGNHGGSSYEETDSLMLFIGLNSNISDYASATNNVAFQVDLAPTLALLFGVPIPKN 341
           GM+E G+HG SS EE ++ ++ I                  Q D+A TLA+  G+PIPK+
Sbjct: 61  GMSETGSHGASSMEEVNTPLILISSAFERKPGDIRHPKHVQQTDVAATLAIALGLPIPKD 120

Query: 342 NVGVLVPGTLCSLRDFEQLRALELNSWQLLRLMLAQIQSSSFPRVSCNCFL------DGT 395
           +VG L+   +      EQLR L LN+ QL +L+   + S           +      +  
Sbjct: 121 SVGSLLFPVVEGRPMREQLRFLHLNTVQLSKLLQENVPSYEKDPGFEQFKMSERLHGNWI 180

Query: 396 CEGLDLDISECSGDKEKQLICLFRNAAALHGIWKSKKSTESS---STMEDFSRALDAYNT 452
              L+   SE   +       L +  AAL  +  S  +  +     +M   +  +    T
Sbjct: 181 RLYLEEKHSEVLFNLG--SKVLRQYLAALKTLSLSLSTQVAQYDMYSMMVGTVVVLEVLT 238

Query: 453 FLKTASEWLASKTTEKPVLLLGLGVSAMLLSCFICGTVFLSLFK--EVYHEPKDRVCSLS 510
            L  +      +  E  V L     S   L  ++   V  ++ +       P+ R  +  
Sbjct: 239 LLLLSVPQALHRKAELEVPLSSPEFS---LLFYLVILVLSAIHEKWMALASPQQRGRTGL 295

Query: 511 NLLNLEEVFI 520
            ++   E   
Sbjct: 296 PVMRWSETKA 305
>ref|NP_491098.1| (NM_058697) M01B12.2.p [Caenorhabditis elegans]
 pir||T33168 hypothetical protein M01B12.2 - Caenorhabditis elegans
          Length = 559

 Score =  254 bits (644), Expect = 5e-66
 Identities = 51/465 (10%), Positives = 117/465 (24%), Gaps = 71/465 (15%)

Query: 396 CEGLDLDISECSGDKEKQLICLFRNAAALHGIWKSKKSTESSSTMEDFSRALDAYNTFLK 455
            E L   +++   D  +  +     A   H + ++             +    ++  ++ 
Sbjct: 1   MESLRTTLAQLGRD-RRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIA 59

Query: 456 TASEWLASKTTEKPVLLLGLG--VSAMLLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLL 513
               +L + T+++ + LL         L    +  T + SL           +  +S L 
Sbjct: 60  LVVSFLHNSTSKENLSLLVPHHLFIIPLACSLL-FTAYCSLSMTQTIYIILPIYLISILE 118

Query: 514 NLEEVFIFALLLILVISMGS---SSMVEEEHYIWHFMVS-----TFHLLLLFKTAKSFKI 565
           N  ++       +  +S      + ++  E ++  F+       T  +  +        +
Sbjct: 119 NHSKLTQRIREHVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICI-FVLTFMDRAFL 177

Query: 566 SKGMNILRDFKFGSIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLIS 625
           +    +L             S  ++  W +             WL       +       
Sbjct: 178 AAVFVLLMALP------QFYSHPIVSYWSKT------------WLTLCLVLCIFPFLPAV 219

Query: 626 ---------IILVIGLGLY--TLFRTGSNRKGVRIL--------AFGFSTCGFLVLLHVG 666
                    I+  I        L R     +  R+L        A  F            
Sbjct: 220 GVSTHIPLCILSPIITAFLCHRLSRRSCLTRIQRMLELMIYVQSATAFMIAVVNYGFEKV 279

Query: 667 RYQ-----------------DELSTGFGATVTVKVIYYLLSI-SSIGASLVLPWSALNKD 708
           +                    +  +         +   +++     G  LV    A    
Sbjct: 280 KKLIQNNWKKKKSNSKSSQSLQPPSIARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALC 339

Query: 709 KSFLAEVGDCLYLIGSAYILCWCLLQQLLQQPINSGPILLLLLQILAILCLSSSDFQVNE 768
                 +    Y      I    L   +  +  +   + LL    L +     S  +  E
Sbjct: 340 FYVPYSLLSISYESLFMLIFLVLLTLFVRFEFGHLSDVELL---QLKVDSTKISTGEYVE 396

Query: 769 WVEITALYYMGMAGHFALGNSNTLATIDVAGAFIGISSHSTILSG 813
                      +   F  GN  ++ + + +   + IS  S     
Sbjct: 397 LRRTVVCVSFVLCPLFGTGNFASINSFNPSTLNLFISVFSPFTMA 441
>dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like protein [Spinacia
           oleracea]
          Length = 479

 Score =  246 bits (624), Expect = 9e-64
 Identities = 42/302 (13%), Positives = 89/302 (28%), Gaps = 44/302 (14%)

Query: 2   TTAAMTCTRLTIFTVAGILLQIIGLSIFV-FGFFPVKPTLSGVSGSESYRDPFCDSSLIS 60
           T+AA    +  +  ++ +      +   V F F  +  T +    S++ +      SL  
Sbjct: 31  TSAAKPTFQNKVLLISLLSTTFTAVIAAVSFAFLFLSATSAAAGESKTIKITTTARSLTK 90

Query: 61  NESELHHPEKLRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAK 120
               +       ++    DG    +                 P    L+ NG +      
Sbjct: 91  LTHPI-------VILISSDGFRFGYQFKA-----------PTPNIHRLINNGTSAELGLI 132

Query: 121 AAPPTVTMPRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLK 180
              PT+T P   ++V+G       +  N+    +  D               LG+  W  
Sbjct: 133 PVFPTLTFPNHYSIVTGLYPPHHGIINNYFVDPITGDKFSMASHE---PKWWLGEPLWET 189

Query: 181 LFPGL-----------------FMRHDGVSSFFVKDTVQVDRNVSRHL--PDELNSDDWN 221
           +                     +             ++  +  V   +   D   ++   
Sbjct: 190 VAKHGKKAATYFWPGSEVIKPDWDCPSNYC-IHYNGSIPFEERVDTVISYFDLPINEIPV 248

Query: 222 LLILHYLGLDHVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDH 281
            + L++   DH GH  G + P +   +  +D ++  +          +     + +V DH
Sbjct: 249 FMTLYFEDPDHQGHQVGPDDPEITQAVINIDKMIGRLIKGLEKRGVFEDVN--IFMVGDH 306

Query: 282 GM 283
           GM
Sbjct: 307 GM 308
>ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09932 nucleotide pyrophosphatase homolog T16L4.200 - Arabidopsis thaliana
 emb|CAB45329.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79727.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 457

 Score =  243 bits (616), Expect = 7e-63
 Identities = 38/275 (13%), Positives = 80/275 (28%), Gaps = 38/275 (13%)

Query: 33  FFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRLLYQVI--DGLPAEFVLGKD 90
                     +  S +      DS            +  + +  +I  DG    +    +
Sbjct: 15  ILYKLSLTVLIVLSVAVTANGSDSPSSYVRRPQPPKKLNKPVVLLISCDGFRFGYQFKTE 74

Query: 91  GKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLKAMVSGAIGGFLDVAFNFN 150
                       P    L++ G           PT+T P   ++ +G       +  N  
Sbjct: 75  -----------TPNIDLLISRGTEAKTGLIPVFPTMTFPNHYSIATGLYPASHGIIMNKF 123

Query: 151 TQALLDDNILGQFFRIGWKMVMLGDETWLK-----------------LFPGLFMRHDGVS 193
           T  +  +               LG+  W+                  +  G +    G  
Sbjct: 124 TDPVSGELFNRNLNPK----WWLGEPLWVTAVNQGLMAATYFWPGADVHKGSWNCPKGFC 179

Query: 194 SFFVKDTVQVDRNVSRHL--PDELNSDDWNLLILHYLGLDHVGHTGGRNSPLMPAKLKEM 251
                 +V ++  V   L   D    +  + + L++   D  GH  G + P +   + ++
Sbjct: 180 KAPYNVSVPLEERVDTILNYFDLPEREIPDFMALYFDEPDIQGHEYGPDDPRVTEAVSKV 239

Query: 252 DDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTEN 286
           D ++  + +     +        +I++ DHGM  N
Sbjct: 240 DKMIGRIIMGLEKRKVFSDVH--VILLGDHGMVTN 272
>dbj|BAB55130.1| (AK027465) unnamed protein product [Homo sapiens]
          Length = 549

 Score =  239 bits (606), Expect = 1e-61
 Identities = 73/299 (24%), Positives = 127/299 (42%), Gaps = 26/299 (8%)

Query: 556 LFKTAKSFKISKGMNILRD--FK-FGSIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQ 612
           L +       S    +     +    S + +L   RLLR  +Q GV W + PD+  WL  
Sbjct: 197 LERDKGHGSPSTSEVLRGREKWMVLASPWLILACCRLLRSLNQTGVQWAHRPDLGHWLTS 256

Query: 613 GGSGYVKWIQLISIILVIGLGLYTLFRTGSNRKGVRILAF-GFSTCGFLVLLHVGRY--- 668
                    +L  +  +  L ++ L + G +      LA        +   +   R+   
Sbjct: 257 SDHKA----ELSVLAALSLLVVFVLVQRGCSPVSKAALALGLLGVYCYRAAIGSVRFPWR 312

Query: 669 --QDELSTGFGATVTVKVIY-YLLSISSIGASLVLPWSALNKDKSFLAEVGDCLYLIGSA 725
               ++S G    +  + +Y ++L I   G   +L    +  D   L  VG  L+ I S 
Sbjct: 313 PDSKDISKG---IIEARFVYVFVLGILFTGTKDLLKSQVIAADF-KLKTVG--LWEIYSG 366

Query: 726 YILCWCLLQQLLQQPINSGPILLLLLQILAILCLSSSDFQVNEWVEITAL-YYMGMAGHF 784
            +    LL  LL +P N  P+L   L I  ++         ++  EIT + Y+ G A  +
Sbjct: 367 LV----LLAALLFRPHNL-PVLAFSLLIQTLMTKFIWKPLRHDAAEITVMHYWFGQAFFY 421

Query: 785 ALGNSNTLATIDVAGAFIGISSHSTILSGILMFMITYASPMLFLLSLVMYIGANLRNHS 843
             GNSN +AT+D++  F+G+ ++  I + +L    TYA P+L+   LV ++ +  R+ S
Sbjct: 422 FQGNSNNIATVDISAGFVGLDTYVEIPAVLLTAFGTYAGPVLWASHLVHFLSSETRSGS 480
 Score =  115 bits (287), Expect = 3e-24
 Identities = 34/170 (20%), Positives = 62/170 (36%), Gaps = 12/170 (7%)

Query: 405 ECSGDKEKQLICLFRNAAALHGIWKSKKSTESSSTMEDFSRALDAYNTFLKTASEWLASK 464
              G      +      +    + +     E    +     +L  Y   L  ++  +   
Sbjct: 1   MMVGTVVVLEVLTLLLLSVPQALRRKA---ELEVPLSSPGFSLLFYLVILVLSAVHVIVC 57

Query: 465 TTEKPV------LLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEV 518
           T+ +          L  G   +L S  +C  V   L   +      R   +       E+
Sbjct: 58  TSAESSCYFCGLSWLAAGGVMVLASALLCVIV-SVLTNVLVGGNTPRKNPMHPSSRWSEL 116

Query: 519 FIFALL--LILVISMGSSSMVEEEHYIWHFMVSTFHLLLLFKTAKSFKIS 566
            +  LL     V+S+G+SS VEEEH  W+F+V+T  L L  +T +++ + 
Sbjct: 117 DLLILLGTAGHVLSLGASSFVEEEHQTWYFLVNTLCLALSQETYRNYFLG 166
>ref|NP_060203.1| (NM_017733) hypothetical protein FLJ20265 [Homo sapiens]
 dbj|BAA91046.1| (AK000272) unnamed protein product [Homo sapiens]
 gb|AAH01249.1|AAH01249 (BC001249) hypothetical protein FLJ20265 [Homo sapiens]
          Length = 604

 Score =  239 bits (605), Expect = 2e-61
 Identities = 73/299 (24%), Positives = 127/299 (42%), Gaps = 26/299 (8%)

Query: 556 LFKTAKSFKISKGMNILRD--FK-FGSIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQ 612
           L +       S    +     +    S + +L   RLLR  +Q GV W + PD+  WL  
Sbjct: 252 LERDKGHGSPSTSEVLRGREKWMVLASPWLILACCRLLRSLNQTGVQWAHRPDLGHWLTS 311

Query: 613 GGSGYVKWIQLISIILVIGLGLYTLFRTGSNRKGVRILAF-GFSTCGFLVLLHVGRY--- 668
                    +L  +  +  L ++ L + G +      LA        +   +   R+   
Sbjct: 312 SDHKA----ELSVLAALSLLVVFVLVQRGCSPVSKAALALGLLGVYCYRAAIGSVRFPWR 367

Query: 669 --QDELSTGFGATVTVKVIY-YLLSISSIGASLVLPWSALNKDKSFLAEVGDCLYLIGSA 725
               ++S G    +  + +Y ++L I   G   +L    +  D   L  VG  L+ I S 
Sbjct: 368 PDSKDISKG---IIEARFVYVFVLGILFTGTKDLLKSQVIAADF-KLKTVG--LWEIYSG 421

Query: 726 YILCWCLLQQLLQQPINSGPILLLLLQILAILCLSSSDFQVNEWVEITAL-YYMGMAGHF 784
            +    LL  LL +P N  P+L   L I  ++         ++  EIT + Y+ G A  +
Sbjct: 422 LV----LLAALLFRPHNL-PVLAFSLLIQTLMTKFIWKPLRHDAAEITVMHYWFGQAFFY 476

Query: 785 ALGNSNTLATIDVAGAFIGISSHSTILSGILMFMITYASPMLFLLSLVMYIGANLRNHS 843
             GNSN +AT+D++  F+G+ ++  I + +L    TYA P+L+   LV ++ +  R+ S
Sbjct: 477 FQGNSNNIATVDISAGFVGLDTYVEIPAVLLTAFGTYAGPVLWASHLVHFLSSETRSGS 535
 Score =  138 bits (347), Expect = 3e-31
 Identities = 40/219 (18%), Positives = 75/219 (33%), Gaps = 20/219 (9%)

Query: 356 DFEQLRALELNSWQLLRLMLAQIQSSSFPRVSCNCFLDGTCEGLDLDISECSGDKEKQLI 415
           + +    L     ++LR  L  +++ S                     S   G      +
Sbjct: 15  EEKHSEVLFNLGSKVLRQYLDALKTLSLSL--------SAQVAQYDIYSMMVGTVVVLEV 66

Query: 416 CLFRNAAALHGIWKSKKSTESSSTMEDFSRALDAYNTFLKTASEWLASKTTEKPV----- 470
                 +    + +     E    +     +L  Y   L  ++  +   T+ +       
Sbjct: 67  LTLLLLSVPQALRRKA---ELEVPLSSPGFSLLFYLVILVLSAVHVIVCTSAESSCYFCG 123

Query: 471 -LLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFIFALL--LIL 527
              L  G   +L S  +C  V   L   +      R   +       E+ +  LL     
Sbjct: 124 LSWLAAGGVMVLASALLCVIV-SVLTNVLVGGNTPRKNPMHPSSRWSELDLLILLGTAGH 182

Query: 528 VISMGSSSMVEEEHYIWHFMVSTFHLLLLFKTAKSFKIS 566
           V+S+G+SS VEEEH  W+F+V+T  L L  +T +++ + 
Sbjct: 183 VLSLGASSFVEEEHQTWYFLVNTLCLALSQETYRNYFLG 221
>ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like protein [Arabidopsis
           thaliana]
 pir||T09933 nucleotide pyrophosphatase homolog T16L4.210 - Arabidopsis thaliana
 emb|CAB45330.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79728.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 461

 Score =  239 bits (604), Expect = 2e-61
 Identities = 44/288 (15%), Positives = 90/288 (30%), Gaps = 41/288 (14%)

Query: 20  LLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRLLYQVI- 78
           ++      IF+   F         + + +      DS            +  + +  +I 
Sbjct: 7   VISFKLSLIFLLNIF--IVATIAAAAAVNAGTKGLDSRPSKTRRPWPFKKLNKPVVLMIS 64

Query: 79  -DGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLKAMVSG 137
            DG    +    D            P    L++ G    +      PT+T P   ++ +G
Sbjct: 65  CDGFRFGYQFKTD-----------TPNIDLLISGGTEAKHGLIPVFPTMTFPNHYSIATG 113

Query: 138 AIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLK----------------- 180
               +  +  N  T  +  +               LG+  W+                  
Sbjct: 114 LYPAYHGIIMNKFTDPVTGEVFNKGLQPK----WWLGEPLWVTAVNQGLKAVTYFWPGSE 169

Query: 181 LFPGLFMRHDGV-SSFFVK-DTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVGHTGG 238
           +    +   +G    F +     +   +V  H  D L  +  +LL+L++   D  GH  G
Sbjct: 170 VLKSSWTCPEGYCPHFNLSVPLEERVDSVLSH-FDHLEDEVPDLLMLYFDEPDQSGHNYG 228

Query: 239 RNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTEN 286
            + P +   +  +D ++  +          D+    +I++ DHGM  N
Sbjct: 229 PDDPRVTTAVSRVDKMIGRVIKGLKQREIFDEVH--VILLGDHGMVTN 274
>gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophosphatase [Arabidopsis
           thaliana]
          Length = 456

 Score =  237 bits (599), Expect = 8e-61
 Identities = 45/290 (15%), Positives = 90/290 (30%), Gaps = 42/290 (14%)

Query: 18  GILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRLLYQV 77
            + L     S F+  F          + + +      DS            +  + +  +
Sbjct: 1   MLFLSNFLSSSFLIFF---IVATIAAAAAVNAGTKGLDSRPSKTRRPWPFKKLNKPVVLM 57

Query: 78  I--DGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLKAMV 135
           I  DG    +    D            P    L++ G    +      PT+T P   ++ 
Sbjct: 58  ISCDGFRFGYQFKTD-----------TPNIDLLISGGTEAKHGLIPVFPTMTFPNHYSIA 106

Query: 136 SGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLK--------------- 180
           +G    +  +  N  T  +  +               LG+  W+                
Sbjct: 107 TGLYPAYHGIIMNKFTDPVTGEVFNKGLQPK----WWLGEPLWVTAVNQGLKAVTYFWPS 162

Query: 181 --LFPGLFMRHDGV-SSFFVK-DTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVGHT 236
             +    +   +G    F +     +   +V  H  D L  +  +LL+L++   D  GH 
Sbjct: 163 SEVLKSSWTCPEGYCPHFNLSVPLEERVDSVLSH-FDHLEDEVPDLLMLYFDEPDQSGHN 221

Query: 237 GGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTEN 286
            G + P +   +  +D ++  +          D+    +I++ DHGM  N
Sbjct: 222 YGPDDPRVTTAVSRVDKMIGRVIKGLKQREIFDEVH--VILLGDHGMVTN 269
>ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo sapiens]
 gb|AAH13987.1|AAH13987 (BC013987) Similar to hypothetical protein MGC3079 [Homo sapiens]
          Length = 454

 Score =  234 bits (592), Expect = 5e-60
 Identities = 64/233 (27%), Positives = 99/233 (42%), Gaps = 28/233 (12%)

Query: 215 LNSDDWNLLILHYLGLDHVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTL 274
           ++S +W++LI H+LG+DH GH  G + P M  KL +MD +++ +  R   D       TL
Sbjct: 1   MDSGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLEND-------TL 53

Query: 275 LIIVSDHGMTENGNHGGSSYEETDSLMLFIGLNSNISDYASATNNVAFQVDLAPTLALLF 334
           L++  DHGMT NG+HGG S  E  + +      +           V  QV L PTLALL 
Sbjct: 54  LVVAGDHGMTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPEEPEVIPQVSLVPTLALLL 113

Query: 335 GVPIPKNNVGVLVPGTLCSLRD-------FEQLRALELNSWQLLRLMLAQ------IQSS 381
           G+PIP  N+G ++        D         Q  AL LN+ Q+ R +         +Q+ 
Sbjct: 114 GLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQAK 173

Query: 382 SFPRVSCNC-FLDGTCEGLDLDISECSGDKEKQLICLFRNAAALHGIWKSKKS 433
              ++           + L           +     L    A L    +  ++
Sbjct: 174 ELHQLQNLFSKASADYQWL-------LQSPKGAEATLPTVIAELQQFLRGARA 219
>ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09931 nucleotide pyrophosphatase homolog T16L4.190 - Arabidopsis thaliana
 emb|CAB45328.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79726.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 496

 Score =  230 bits (581), Expect = 1e-58
 Identities = 51/290 (17%), Positives = 92/290 (31%), Gaps = 39/290 (13%)

Query: 13  IFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLR 72
           IFT   ++  I   +   F F         +S ++  + P  D    S    L   +K  
Sbjct: 52  IFTSLLLVTCIALSAASAFAFLFFSSQKPVLSLNQISKSPAFDR---SVARPLKKLDKPV 108

Query: 73  LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLK 132
           +L    DG    +                +P    L+ANG           PT+T P   
Sbjct: 109 VLLISSDGFRFGYQFKT-----------KLPSIHRLIANGTEAETGLIPVFPTLTFPNHY 157

Query: 133 AMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLK------------ 180
           ++V+G    +  +  N        +               LG+  W              
Sbjct: 158 SIVTGLYPAYHGIINNHFVDPETGNVFTMASHE---PEWWLGEPLWETVVNQGLKAATYF 214

Query: 181 -----LFPGLFMRHDGVSSFFVKDTVQVDRNVSRHL--PDELNSDDWNLLILHYLGLDHV 233
                +  G +    G+       +V  D  V   L   D  +++  + + L++   DH 
Sbjct: 215 WPGSEVHKGSWNCPQGLCQ-NYNGSVPFDDRVDTILSYFDLPSNEIPSFMTLYFEDPDHQ 273

Query: 234 GHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGM 283
           GH  G + P +   +  +D ++  +          +     +I+V DHGM
Sbjct: 274 GHQVGPDDPQITEAVVNIDRLIGRLIDGLEKRGIFEDV--TMIMVGDHGM 321
>ref|NP_116023.1| (NM_032634) hypothetical protein MGC3079 [Homo sapiens]
 gb|AAH01030.1|AAH01030 (BC001030) Similar to phosphatidylinositol glycan, class O [Homo
           sapiens]
          Length = 454

 Score =  225 bits (568), Expect = 4e-57
 Identities = 62/233 (26%), Positives = 95/233 (40%), Gaps = 28/233 (12%)

Query: 215 LNSDDWNLLILHYLGLDHVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTL 274
           ++S +W +   H LG+DH GH  G + P M  KL +MD +++ +  R   D       TL
Sbjct: 1   MDSGEWEVSNQHVLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLEND-------TL 53

Query: 275 LIIVSDHGMTENGNHGGSSYEETDSLMLFIGLNSNISDYASATNNVAFQVDLAPTLALLF 334
           L++  DHGMT NG+HGG S  E  + +      +           V  QV L PTLALL 
Sbjct: 54  LVVAGDHGMTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPEEPEVIPQVSLVPTLALLL 113

Query: 335 GVPIPKNNVGVLVPGTLCSLRD-------FEQLRALELNSWQLLRLMLAQ------IQSS 381
           G+PIP  N+G ++        D         Q  AL LN+ Q+ R +         +Q+ 
Sbjct: 114 GLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQAK 173

Query: 382 SFPRVSCNC-FLDGTCEGLDLDISECSGDKEKQLICLFRNAAALHGIWKSKKS 433
              ++           + L           +     L    A L    +  ++
Sbjct: 174 ELHQLQNLFSKASADYQWL-------LQSPKGAEATLPTVIAELQQFLRGARA 219
>pir||T03293 nucleotide pyrophosphatase homolog - rice
 gb|AAA67067.1| (U25430) nucleotide pyrophosphatase precursor [Oryza sativa]
 gb|AAF65458.1|AF245483_1 (AF245483) OSE4 [Oryza sativa]
 dbj|BAB56086.1| (AP003244) nucleotide pyrophosphatase homolog [Oryza sativa]
          Length = 479

 Score =  219 bits (553), Expect = 2e-55
 Identities = 44/294 (14%), Positives = 88/294 (28%), Gaps = 53/294 (18%)

Query: 9   TRLTIFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHP 68
           +RL +   A + +    L +      P  P  +  + + + R        +         
Sbjct: 45  SRLHLLLTAALAVATSYLLL----ILPRTPLSAAPAPAAAARAQVKLEKPV--------- 91

Query: 69  EKLRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTM 128
               ++    DG    +                 P+   L+ NG +         PT+T 
Sbjct: 92  ----VILISSDGFRFGYQHKAA-----------TPHIHRLIGNGTSAATGLVPIFPTLTF 136

Query: 129 PRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLK-------- 180
           P   ++ +G       +  N+    +  D               LG+  W+         
Sbjct: 137 PNHYSIATGLYPSSHGIINNYFPDPISGDYFTMSSHE---PKWWLGEPLWVTAADQGIQA 193

Query: 181 ---------LFPGLFMRHDGVSSFFVKDTVQVDRNVSRHL--PDELNSDDWNLLILHYLG 229
                    +  G +   D         +V  +  V   L   D  + +    L L++  
Sbjct: 194 ATYFWPGSEVKKGSWDCPDKYCR-HYNGSVPFEERVDAILGYFDLPSDEMPQFLTLYFED 252

Query: 230 LDHVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGM 283
            DH GH  G + P +   +  +D+++  +          +     +I+V DHGM
Sbjct: 253 PDHQGHQVGPDDPAITEAVVRIDEMIGRLIAGLEERGVFEDVN--VILVGDHGM 304
>ref|NP_281901.1| (NC_002163) hypothetical protein Cj0729 [Campylobacter jejuni]
 pir||D81344 hypothetical protein Cj0729 [imported] - Campylobacter jejuni
           (strain NCTC 11168)
 emb|CAB73003.1| (AL139076) hypothetical protein Cj0729 [Campylobacter jejuni]
          Length = 269

 Score =  211 bits (532), Expect = 5e-53
 Identities = 49/277 (17%), Positives = 102/277 (36%), Gaps = 36/277 (12%)

Query: 71  LRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPR 130
            + +  V+DGL              K    +M Y  +L        Y  +   P+++ P 
Sbjct: 3   SKAILVVLDGL------------NCKSASINMGYLNALCKENLGKFYSLECELPSMSRPL 50

Query: 131 LKAMVSGAIGGFLDVAFN---FNTQALLDDNILGQFFRIG-----WKMVMLGDETWLKLF 182
            + +++G       +  N   F+ Q  + D    Q  + G     W   +   + ++   
Sbjct: 51  YECLLTGVKPVLSGIINNKLSFSKQTSIFDLCKEQGLKAGGAAYHWVFELYNKKEFIPSL 110

Query: 183 PGLFMR---HDGVSSFFVKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVGHTGGR 239
                          F+ +D   +D ++        N  + +  ++H + +D  GH  G 
Sbjct: 111 HRHIEDENLTLPYGHFYYED-DYLDSHLFADGEHLRNKYNLDFTLIHSMNIDDAGHKFGS 169

Query: 240 NSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDS 299
           +S     K K++D ++   +L   +++  +     +II SDHGMTE  +HGG S +E   
Sbjct: 170 HSIEYANKTKKVDILISE-YLPTWLEQGIN-----VIITSDHGMTEGKSHGGLSEDEILV 223

Query: 300 LMLFIGLNSNISDYASATNNVAFQVDLAPTLALLFGV 336
                G   +  +     +       +  ++  + G+
Sbjct: 224 PFFTFGSAFSYENAKIKQDE------ICGSICEILGL 254
>ref|NP_105837.1| (NC_002678) hypothetical protein [Mesorhizobium loti]
 dbj|BAB51623.1| (AP003005) hypothetical protein [Mesorhizobium loti]
          Length = 298

 Score =  205 bits (519), Expect = 2e-51
 Identities = 54/294 (18%), Positives = 107/294 (36%), Gaps = 52/294 (17%)

Query: 70  KLRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMP 129
           K +LL  ++DG+P             +  +  M   +  + +G+A  +  ++  P+ +  
Sbjct: 23  KSKLLLIILDGVPY------------RNWRRLMGNLEGWVQSGEARVWKMRSVLPSTSAC 70

Query: 130 RLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMRH 189
              ++ +G       +  N N   +   +I  +  + G K   +    W       F R 
Sbjct: 71  CYASIHTGVSPQVHGILSNENRFRVGQPDIFSEVSKAGGKTGAVTHSYW-----SEFFRS 125

Query: 190 DGVSSFFVKDTVQVDRNVSRHLP---------DELNSDDWNLL---------------IL 225
                    +  +    ++             +++   D +L                IL
Sbjct: 126 YPFDLVEDMEYDEPGGPITHGRFHTMTGYNARNQMTPSDVDLFATLTMLTKRHGIDYGIL 185

Query: 226 HYLGLDHVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTE 285
           H   LD +GH  G +   M   +  MD ++    L   +   ++     +++ +DHG T+
Sbjct: 186 HTCTLDSMGHRFGNDCHEMDHAVYAMDGMLAAF-LPGWIAAGYE-----VMVTADHGQTD 239

Query: 286 NGNHGGSSYEETDSLMLFIGLNSNISDYASATNNVAFQVDLAPTLALLFGVPIP 339
            G+HGG   E  D  + + G           T+ +  Q+ LAPT+    GVP+P
Sbjct: 240 RGHHGGHDDEMQDFALYYFGQGQ-----GPETDTLLDQLQLAPTVLSRLGVPVP 288
>ref|NP_114392.1| (NM_032003) ectonucleotide pyrophosphatase/phosphodiesterase 5 [Mus
           musculus]
 gb|AAG49143.1|AF233377_1 (AF233377) putative nucleotide pyrophosphatase/phosphodiesterase;
           NPP5 [Mus musculus]
          Length = 477

 Score =  195 bits (491), Expect = 4e-48
 Identities = 44/233 (18%), Positives = 89/233 (37%), Gaps = 31/233 (13%)

Query: 68  PEKLRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVT 127
           PE+ ++L    DG   +++            K   P+   ++ NG  +         T T
Sbjct: 25  PEEQKVLVVSFDGFRWDYL-----------YKVPTPHFHYIMKNGVHVNQVTNVFI-TKT 72

Query: 128 MPRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGD--ETWLK----- 180
            P    +V+G       +  N     +L+ +   +     +      +    W+      
Sbjct: 73  YPNHYTLVTGLFAENHGIVANDMFDPILNKSFSLE-HMDIYDSKFWEEATPIWITNQRAG 131

Query: 181 ------LFPGLFMR-HDGVSSFF--VKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLD 231
                 ++PG  ++ HD   +++    ++V  +  V++ +      D  NL  L++   D
Sbjct: 132 HASGAAMWPGADVKIHDSFPTYYLPYNESVSFEDRVAKIIEWFTAKDPINLGFLYWEEPD 191

Query: 232 HVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMT 284
             GH  G +SPLM + + ++D  +  +       +  +     LI+ SDHGMT
Sbjct: 192 DTGHDVGPDSPLMGSVISDVDHKLGYLIKMLKRAKLWNNVN--LIVTSDHGMT 242
>gb|AAH11294.1|AAH11294 (BC011294) ectonucleotide pyrophosphatase/phosphodiesterase 5 [Mus
           musculus]
          Length = 477

 Score =  195 bits (491), Expect = 4e-48
 Identities = 44/233 (18%), Positives = 89/233 (37%), Gaps = 31/233 (13%)

Query: 68  PEKLRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVT 127
           PE+ ++L    DG   +++            K   P+   ++ NG  +         T T
Sbjct: 25  PEEQKVLVVSFDGFRWDYL-----------YKVPTPHFHYIMKNGVHVNQVTNVFI-TKT 72

Query: 128 MPRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGD--ETWLK----- 180
            P    +V+G       +  N     +L+ +   +     +      +    W+      
Sbjct: 73  YPNHYTLVTGLFAENHGIVANDMFDPILNKSFSLE-HMDIYDSKFWEEATPIWITNQRAG 131

Query: 181 ------LFPGLFMR-HDGVSSFF--VKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLD 231
                 ++PG  ++ HD   +++    ++V  +  V++ +      D  NL  L++   D
Sbjct: 132 HASGAAMWPGADVKIHDSFPTYYLPYNESVSFEDRVAKIIEWFTAKDPINLGFLYWEEPD 191

Query: 232 HVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMT 284
             GH  G +SPLM + + ++D  +  +       +  +     LI+ SDHGMT
Sbjct: 192 DTGHDVGPDSPLMGSVISDVDHKLGYLIKMLKRAKLWNNVN--LIVTSDHGMT 242
>dbj|BAA87261.1| (AB027957) Hypothetical protein [Schizosaccharomyces pombe]
          Length = 179

 Score =  191 bits (483), Expect = 3e-47
 Identities = 34/183 (18%), Positives = 75/183 (40%), Gaps = 19/183 (10%)

Query: 217 SDDWNLLILHYLGLDHVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLI 276
             D  +  LH LG+D +GH    +S      ++ +D  ++ +  +   +  ++ G +  +
Sbjct: 1   HRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKM-NNYYNNDGASSWV 59

Query: 277 IVSDHGMTENGNHGGSSYEETDSLMLFIGLNSNIS----DYASATNN-----------VA 321
             +DHGM++ G+HG  + + T + ++  G          +Y     +             
Sbjct: 60  FTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDI 119

Query: 322 FQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLRLMLAQIQSS 381
            Q D+A  ++ L G+  P N+VG +    L       +     +N+ ++       ++S+
Sbjct: 120 QQADIAALMSYLVGLNFPVNSVGQIPLDYL-DCSSRRKAEVALMNALEIGEQY--NLKSA 176

Query: 382 SFP 384
           S  
Sbjct: 177 SKD 179
>pir||T40657 probable phophodiesterase-nucleotide pyrophosp hatase precursor -
           fission yeast (Schizosaccharomyces pombe)
 emb|CAA22177.1| (AL034352) putative nucleotide pyrophosphatase precursor
           [Schizosaccharomyces pombe]
          Length = 485

 Score =  190 bits (479), Expect = 9e-47
 Identities = 37/239 (15%), Positives = 79/239 (32%), Gaps = 42/239 (17%)

Query: 73  LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLK 132
           ++   +DG  A+++            +   P   SL      + +    + P++T P   
Sbjct: 76  VIVISLDGFRADYL-----------YRGFTPNLLSLAERNVHVPF-LIPSFPSITFPNHY 123

Query: 133 AMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVML--GDETWLKLFPGLFMRHD 190
            +V+G       +  N     +     +               G+  W+        R++
Sbjct: 124 TIVTGLYPESHGIVSNNFFDPVTGKQFVNSMPECNKDPTWWDKGEPIWVN-----AERNN 178

Query: 191 GVSSFFVKDTVQVDRNV-------------------SRHLPD--ELNSDDWNLLILHYLG 229
             S+  +    +V+ +                     R L      + D   LL+ +   
Sbjct: 179 VRSAVHMWPGNEVENHGYRPTYSDGFNFDTTLREKKDRILEWLDLPDKDRPQLLLAYAPH 238

Query: 230 LDHVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGN 288
           +D VGH  G +SP +   ++E+D ++  +         +      +I +SDHGM    +
Sbjct: 239 VDMVGHAFGPDSPELNIIIQEVDIVIGELIEGLKKR--NIDKHVNIIFLSDHGMAPTSD 295
>ref|NP_251941.1| (NC_002516) hypothetical protein [Pseudomonas aeruginosa]
 pir||E83240 hypothetical protein PA3251 [imported] - Pseudomonas aeruginosa
           (strain PAO1)
 gb|AAG06639.1|AE004747_12 (AE004747) hypothetical protein [Pseudomonas aeruginosa]
          Length = 269

 Score =  190 bits (479), Expect = 9e-47
 Identities = 51/278 (18%), Positives = 95/278 (33%), Gaps = 42/278 (15%)

Query: 73  LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLK 132
           ++  ++DGL               V ++ M + Q+L   G    Y  +   P+++ P  +
Sbjct: 5   VILVLLDGL------------NHSVARDCMGHLQALCGAGRGQSYRLECELPSLSRPLYE 52

Query: 133 AMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDET---WLKL------FP 183
            +++G       +        ++  +     F       +        W+        F 
Sbjct: 53  CILTGVPP----IDSGILHNDVVRLSQEQSLFHYARAAGLSTAAAAYHWVSELYNRAPFD 108

Query: 184 GLFMRHDGVSSFFVK--DTVQVDRNVSRHLPD----ELNSDDWNLLILHYLGLDHVGHTG 237
               RH   S+  ++       D     HL             N +++H + +D  GH  
Sbjct: 109 PARDRHTDDSALPIQRGHFYWSDHYPDSHLFADAESLRRRHAPNFMLVHSMNIDDAGHRH 168

Query: 238 GRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEET 297
           G  SP      +  D ++   +L   +   +      + I +DHGM E+ +HGG   EE 
Sbjct: 169 GLASPAYRNAARRADALLSE-YLHQWLAAGYQ-----VAITADHGMNEDRSHGGILEEER 222

Query: 298 DSLMLFIGLNSNISDYASATNNVAFQVDLAPTLALLFG 335
           +  +   G   +  D A        Q DL  TL  + G
Sbjct: 223 EVPLFVFGDAFSRDDLA-----QPLQTDLCGTLCEILG 255
>ref|NP_067547.1| (NM_021572) ectonucleotide pyrophosphatase/phosphodiesterase 5
           (putative function) [Homo sapiens]
 emb|CAB56566.1| (AL035701) dJ8B1.3 (similar to PLASMA-CELL MEMBRANE GLYCOPROTEIN
           PC-1) [Homo sapiens]
          Length = 477

 Score =  189 bits (477), Expect = 1e-46
 Identities = 40/233 (17%), Positives = 86/233 (36%), Gaps = 31/233 (13%)

Query: 68  PEKLRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVT 127
           P++ ++L    DG   +++            K   P+   ++  G  +         T T
Sbjct: 25  PDQQKVLLVSFDGFRWDYL-----------YKVPTPHFHYIMKYGVHVKQVTNVFI-TKT 72

Query: 128 MPRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGD--ETWLK----- 180
            P    +V+G       +  N     + + +         +      +    W+      
Sbjct: 73  YPNHYTLVTGLFAENHGIVANDMFDPIRNKSF-SLDHMNIYDSKFWEEATPIWITNQRAG 131

Query: 181 ------LFPGLFMR-HDGVSSFF--VKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLD 231
                 ++PG  ++ H    + +    ++V  +  V++ +    + +  NL +L++   D
Sbjct: 132 HTSGAAMWPGTDVKIHKRFPTHYMPYNESVSFEDRVAKIIEWFTSKEPINLGLLYWEDPD 191

Query: 232 HVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMT 284
            +GH  G +SPLM   + ++D  +  +       +  +     LII SDHGMT
Sbjct: 192 DMGHHLGPDSPLMGPVISDIDKKLGYLIQMLKKAKLWNTLN--LIITSDHGMT 242
>ref|NP_299876.1| (NC_002488) phosphodiesterase-nucleotide pyrophosphatase precursor
           [Xylella fastidiosa 9a5c]
 pir||B82537 phosphodiesterase-nucleotide pyrophosphatase precursor XF2599
           [imported] - Xylella fastidiosa (strain 9a5c)
 gb|AAF85396.1|AE004067_3 (AE004067) phosphodiesterase-nucleotide pyrophosphatase precursor
           [Xylella fastidiosa 9a5c]
          Length = 433

 Score =  183 bits (462), Expect = 1e-44
 Identities = 46/239 (19%), Positives = 86/239 (35%), Gaps = 35/239 (14%)

Query: 70  KLRLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMP 129
           K +LL  +IDGL A+ +                P    L ++G    +    + P +T+P
Sbjct: 37  KYKLLLILIDGLRADAL-----------EHGQAPQLARLASDGVHALW-MTPSYPALTLP 84

Query: 130 RLKAMVSGAIGGFLDVAFNFNTQAL--LDDNILGQFFRIGWKMVMLGDETWLK------- 180
               +++G       +  N     L    ++   +    G      G+  W+        
Sbjct: 85  NAYTLITGLRPDHHGIVHNTMEDPLLGAFESENQEAISDGR--WWGGEPIWVSAEHAGIH 142

Query: 181 ----LFPGLFMRHDGV-SS--FFVKDTVQVDRNVSRHLPD--ELNSDDWNLLILHYLGLD 231
               L+PG      G   S  +     +  D  +++ L    E   D   L+IL +  ++
Sbjct: 143 SATFLWPGSEASIAGTRPSRWYAYNKHISADTQITQALRWLNERGPDAPRLVILRFEQVN 202

Query: 232 HVGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTEN-GNH 289
             G++ G +SP   A +  +D  +  +              T +I+VSD G+    G+H
Sbjct: 203 TAGNSFGPDSPQYAAAVHMIDSAIGRLIDSLRQHGKLTD--TDVIVVSDQGIAPIPGDH 259
>ref|NP_038993.1| (NC_002188) ORF FPV030 Alkaline phosphodiesterase [Fowlpox virus]
 gb|AAF44374.1|AF198100_21 (AF198100) ORF FPV030 Alkaline phosphodiesterase [Fowlpox virus]
          Length = 817

 Score =  179 bits (450), Expect = 2e-43
 Identities = 42/244 (17%), Positives = 81/244 (32%), Gaps = 45/244 (18%)

Query: 66  HHPEKLR--LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAP 123
             PE  R  L+   ++G   +++            ++ +P  + L+ +G       +   
Sbjct: 111 CPPEFERPPLILIAMNGFRYDYL---------NKWEKYIPTIKDLMEHGVTAP--MRPVY 159

Query: 124 PTVTMPRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFP 183
           PT T P L ++V+G       +  N       D                 G+  W  +  
Sbjct: 160 PTNTFPNLYSIVTGLYPISHGITDNEFIDRGTDIEFTIASEETEEVEWFGGEPIWTTIMK 219

Query: 184 GLFMRHDGVSSFFVKDTVQVDRNVSRHLPDELNSDDWNL-------LILHYLGLDH---- 232
             F       +FF   + +V   V R  P    S + ++        +L +L +D     
Sbjct: 220 NGFKSA----TFFWPGSDKV---VPRKRPTMYRSYNKSVPYEERINTVLRWLKMDTGYRP 272

Query: 233 ------------VGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSD 280
                        G+  G +   +   L+++D  +  +       +        LI+VSD
Sbjct: 273 YFYALYLEEPGSSGYEYGTDDERVGKALEKVDKAIALLMKGLKDLQLIGCAN--LILVSD 330

Query: 281 HGMT 284
           HGM+
Sbjct: 331 HGMS 334
 Score =  179 bits (450), Expect = 2e-43
 Identities = 42/244 (17%), Positives = 81/244 (32%), Gaps = 45/244 (18%)

Query: 66  HHPEKLR--LLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAP 123
             PE  R  L+   ++G   +++            ++ +P  + L+ +G       +   
Sbjct: 111 CPPEFERPPLILIAMNGFRYDYL---------NKWEKYIPTIKDLMEHGVTAP--MRPVY 159

Query: 124 PTVTMPRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFP 183
           PT T P L ++V+G       +  N       D                 G+  W  +  
Sbjct: 160 PTNTFPNLYSIVTGLYPISHGITDNEFIDRGTDIEFTIASEETEEVEWFGGEPIWTTIMK 219

Query: 184 GLFMRHDGVSSFFVKDTVQVDRNVSRHLPDELNSDDWNL-------LILHYLGLDH---- 232
             F       +FF   + +V   V R  P    S + ++        +L +L +D     
Sbjct: 220 NGFKSA----TFFWPGSDKV---VPRKRPTMYRSYNKSVPYEERINTVLRWLKMDTGYRP 272

Query: 233 ------------VGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSD 280
                        G+  G +   +   L+++D  +  +       +        LI+VSD
Sbjct: 273 YFYALYLEEPGSSGYEYGTDDERVGKALEKVDKAIALLMKGLKDLQLIGCAN--LILVSD 330

Query: 281 HGMT 284
           HGM+
Sbjct: 331 HGMS 334
CPU time:   223.12 user secs.	    3.49 sys. secs	  226.61 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.315    0.172    0.449 

Gapped
Lambda     K      H
   0.270   0.0604    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 585202345
Number of Sequences: 887402
Number of extensions: 32719077
Number of successful extensions: 119598
Number of sequences better than 10.0: 1071
Number of HSP's better than 10.0 without gapping: 125
Number of HSP's successfully gapped in prelim test: 967
Number of HSP's that attempted gapping in prelim test: 117469
Number of HSP's gapped (non-prelim): 2232
length of query: 897
length of database: 277,845,442
effective HSP length: 57
effective length of query: 840
effective length of database: 227,263,528
effective search space: 190901363520
effective search space used: 190901363520
T: 11
A: 40
X1: 15 ( 6.8 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.2 bits)
S2: 78 (34.4 bits)