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GPI Anchor Biosynthesis Report: XP_331144.1 (GAA1 family, Neurospora crassa)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 
         (454 letters)

Database: nr
           1,543,518 sequences; 504,497,942 total letters

Searching..................................................

Converged !!!


Results of PSI-Blast iteration 2

Distribution of 26 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)

ref|XP_331144.1| hypothetical protein [Neurospora crassa] >gi|28... 688 0.0
emb|CAD60753.1| unnamed protein product [Podospora anserina] 642 0.0
gb|EAA51928.1| hypothetical protein MG03523.4 [Magnaporthe grise... 625 e-177
ref|XP_235447.2| similar to glycosylphosphatidylinositol anchor ... 555 e-156
ref|NP_034461.1| GPI anchor attachment protein 1 [Mus musculus] ... 550 e-155
ref|NP_003792.1| anchor attachment protein 1; glycophosphatidyli... 533 e-150
gb|AAH60413.1| Unknown (protein for MGC:68658) [Xenopus laevis] 519 e-146
gb|AAH06383.2| GPAA1 protein [Homo sapiens] 454 e-126
ref|NP_572273.2| CG3033-PA [Drosophila melanogaster] >gi|7290645... 452 e-126
gb|AAK77275.1| GH05723p [Drosophila melanogaster] 452 e-125
ref|XP_311451.1| ENSANGP00000018454 [Anopheles gambiae] >gi|2129... 448 e-124
ref|NP_593498.1| putative glycosylphosphatidylinositol anchor at... 448 e-124
ref|NP_013189.1| ER protein essential for attaching GPI (glycosy... 433 e-120
pir||T46923 hypothetical protein DKFZp434E1512.1 - human >gi|701... 410 e-113
pir||T32771 hypothetical protein F33D11.9b - Caenorhabditis elegans 394 e-108
ref|NP_491700.2| anchor attachment protein 1 (1G434) [Caenorhabd... 390 e-107
ref|NP_916949.1| putative GPAA1 - like protein [Oryza sativa (ja... 366 e-100
gb|AAO00773.1| GPAA1 - like protein [Arabidopsis thaliana] 241 3e-62
ref|NP_197414.2| GPAA1 - like protein [Arabidopsis thaliana] 241 3e-62
gb|EAA16082.1| hypothetical protein [Plasmodium yoelii yoelii] 231 4e-59
ref|NP_705572.1| hypothetical protein [Plasmodium falciparum 3D7... 230 9e-59
emb|CAB86709.1| hypothetical protein L3640.14 [Leishmania major] 214 4e-54
dbj|BAC81736.1| GPI transamidase component GAA1 [Trypanosoma bru... 192 2e-47
ref|XP_290985.3| similar to LIM and senescent cell antigen-like ... 179 1e-43
Alignments
>ref|XP_331144.1| hypothetical protein [Neurospora crassa]
 gb|EAA30553.1| hypothetical protein [Neurospora crassa]
          Length = 454

 Score =  688 bits (1759), Expect = 0.0
 Identities = 454/454 (100%), Positives = 454/454 (100%)

Query: 1   MPRLLASALSLRRDPRLLKLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQV 60
           MPRLLASALSLRRDPRLLKLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQV
Sbjct: 1   MPRLLASALSLRRDPRLLKLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQV 60

Query: 61  HTYFGGSDQNVFRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNFTYSSAGNTHS 120
           HTYFGGSDQNVFRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNFTYSSAGNTHS
Sbjct: 61  HTYFGGSDQNVFRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNFTYSSAGNTHS 120

Query: 121 GQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSKDIIFL 180
           GQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSKDIIFL
Sbjct: 121 GQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSKDIIFL 180

Query: 181 FTPDSIAGPQAWVDAYHDAHDSSRVASLPLKSGALQGAIALDYTRETRFQSVHIVYDGVN 240
           FTPDSIAGPQAWVDAYHDAHDSSRVASLPLKSGALQGAIALDYTRETRFQSVHIVYDGVN
Sbjct: 181 FTPDSIAGPQAWVDAYHDAHDSSRVASLPLKSGALQGAIALDYTRETRFQSVHIVYDGVN 240

Query: 241 GQLPNLDLINSVNHVAGGQMGMGVAIQEMWKHSNSYHDRLQTMLRGMLKQGLGLASGPHS 300
           GQLPNLDLINSVNHVAGGQMGMGVAIQEMWKHSNSYHDRLQTMLRGMLKQGLGLASGPHS
Sbjct: 241 GQLPNLDLINSVNHVAGGQMGMGVAIQEMWKHSNSYHDRLQTMLRGMLKQGLGLASGPHS 300

Query: 301 SFIPYHVDAVTLQPFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQSFFFYLLMQRERFVS 360
           SFIPYHVDAVTLQPFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQSFFFYLLMQRERFVS
Sbjct: 301 SFIPYHVDAVTLQPFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQSFFFYLLMQRERFVS 360

Query: 361 IGTYLPSAMLVAANFTIMAIALWVKSGQPDVQEIITEKTKTAEEAERIVSPNPHVASERD 420
           IGTYLPSAMLVAANFTIMAIALWVKSGQPDVQEIITEKTKTAEEAERIVSPNPHVASERD
Sbjct: 361 IGTYLPSAMLVAANFTIMAIALWVKSGQPDVQEIITEKTKTAEEAERIVSPNPHVASERD 420

Query: 421 LFLPLVLVAVCQFLGVVPLYLFNHLSESASSALR 454
           LFLPLVLVAVCQFLGVVPLYLFNHLSESASSALR
Sbjct: 421 LFLPLVLVAVCQFLGVVPLYLFNHLSESASSALR 454
>emb|CAD60753.1| unnamed protein product [Podospora anserina]
          Length = 464

 Score =  642 bits (1641), Expect = 0.0
 Identities = 353/450 (78%), Positives = 399/450 (88%), Gaps = 7/450 (1%)

Query: 1   MPRLLASALSLRRDPRLLKLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQV 60
           MPRLL+SAL+LRRDPR+LK+PPYLSLLCI++G VWLFLLPL++YSRRTYISENALLPGQV
Sbjct: 1   MPRLLSSALALRRDPRILKIPPYLSLLCILVGAVWLFLLPLNEYSRRTYISENALLPGQV 60

Query: 61  HTYFGGSDQNVFRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNFTYSSAGNTHS 120
           HTYFGGSDQNV RAYK E + L GK N+E+NDKLESI +GLGLK  RQNFTY +AG T  
Sbjct: 61  HTYFGGSDQNVLRAYKQEVNSLVGKSNVEINDKLESIVRGLGLKTARQNFTYHAAGRTFE 120

Query: 121 GQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSKDIIFL 180
           G+N+YAILQAPRGDATEAIVLVAAW+NVK E+N++GVPLVLTLARYFKRWSLWSKDII L
Sbjct: 121 GENLYAILQAPRGDATEAIVLVAAWENVKHEVNKNGVPLVLTLARYFKRWSLWSKDIIIL 180

Query: 181 FTPDSIAGPQAWVDAYHDAHDSSRVASLPLKSGALQGAIALDYTRETRFQSVHIVYDGVN 240
            +PDSIA PQAWVDAYHDAHD+SRVASLP+KSGALQGAIA+DY +E RF+SVHIVYDGVN
Sbjct: 181 LSPDSIAAPQAWVDAYHDAHDNSRVASLPIKSGALQGAIAIDYVQENRFKSVHIVYDGVN 240

Query: 241 GQLPNLDLINSVNHVAGGQMGMGVAIQEMWKHSNSYHDRLQTMLRGMLKQGLGLASGPHS 300
           GQLPNLDLINSV ++AGGQMGMGVA+QEMW H++ Y DRL+TMLRGMLKQGLGLASGPHS
Sbjct: 241 GQLPNLDLINSVVNIAGGQMGMGVALQEMWNHNDKYPDRLRTMLRGMLKQGLGLASGPHS 300

Query: 301 SFIPYHVDAVTLQPFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQSFFFYLLMQRERFVS 360
           SFIPYHVDAVTLQPFGEGWQDEMA+GRV+EGTFRSLNNLLEHLHQSFFFYLLM RERFVS
Sbjct: 301 SFIPYHVDAVTLQPFGEGWQDEMAMGRVVEGTFRSLNNLLEHLHQSFFFYLLMHRERFVS 360

Query: 361 IGTYLPSAMLVAANFTIMAIALWVKSGQPDVQEIITEKTKTAEEAERIVSPNPHVASERD 420
           IGTYLPSAMLVAANFTIMAI LW+KSGQP++         T E +++  +P P   +ERD
Sbjct: 361 IGTYLPSAMLVAANFTIMAIFLWMKSGQPEI-----PAASTTESSDKDDAPTP--TTERD 413

Query: 421 LFLPLVLVAVCQFLGVVPLYLFNHLSESAS 450
           LFLPL +VA+   L  +PLY+FNH+ ES S
Sbjct: 414 LFLPLAVVALSGSLSAIPLYIFNHVPESVS 443
>gb|EAA51928.1| hypothetical protein MG03523.4 [Magnaporthe grisea 70-15]
          Length = 606

 Score =  625 bits (1595), Expect = e-177
 Identities = 329/446 (73%), Positives = 381/446 (84%), Gaps = 1/446 (0%)

Query: 1   MPRLLASALSLRRDPRLLKLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQV 60
           MPRLL++ LSLRRDPR+LKLPPYLS+LCIV+G+V L LLPLD+++RRTYISENALLPGQV
Sbjct: 1   MPRLLSTVLSLRRDPRILKLPPYLSVLCIVVGIVSLLLLPLDNFTRRTYISENALLPGQV 60

Query: 61  HTYFGGSDQNVFRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNFTYSSAGNTHS 120
           HTYF GSDQNVFRAYKHE + L  K N+E+NDKLESI KG+GLKVGRQNFTYSS+G  HS
Sbjct: 61  HTYFAGSDQNVFRAYKHEVNSLVDKSNVEINDKLESIFKGVGLKVGRQNFTYSSSGIQHS 120

Query: 121 GQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSKDIIFL 180
           G+N+YAILQAPRGDATEAIVLV AW+N  GELNR+GV L LTLARYF+RWSLWSKDIIFL
Sbjct: 121 GENVYAILQAPRGDATEAIVLVTAWRNPNGELNRNGVALALTLARYFRRWSLWSKDIIFL 180

Query: 181 FTPDSIAGPQAWVDAYHDAHDSSRVASLPLKSGALQGAIALDYTRETRFQSVHIVYDGVN 240
             PDS+AGPQAWVDAYHDAHD  +VA+LPLKSGALQGA+ALDYTRE R++SVH+VYDGVN
Sbjct: 181 LPPDSLAGPQAWVDAYHDAHDPRKVAALPLKSGALQGALALDYTREDRYESVHLVYDGVN 240

Query: 241 GQLPNLDLINSVNHVAGGQMGMGVAIQEMWKHSNSYHDRLQTMLRGMLKQGLGLASGPHS 300
           GQLPNLDL NS+ HVAGGQMG+GV+IQ+MW H N Y DRLQTMLRGML+QG+G  +G HS
Sbjct: 241 GQLPNLDLFNSLVHVAGGQMGIGVSIQDMWHHRNDYRDRLQTMLRGMLRQGIGAGTGAHS 300

Query: 301 SFIPYHVDAVTLQPFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQSFFFYLLMQRERFVS 360
            F+PYHVDAVTL P+G+GWQDEMA+GRV+EGTFRSLNNLLEHLHQSFFFYLLM +E FVS
Sbjct: 301 CFMPYHVDAVTLVPYGDGWQDEMALGRVVEGTFRSLNNLLEHLHQSFFFYLLMHKEHFVS 360

Query: 361 IGTYLPSAMLVAANFTIMAIALWVKSGQPDVQEIITEKTKTAEEAERIVSPNPHVASERD 420
           IGTYLPSAML+ ANFTIM+I +W KSGQP+ +E    +         + S +  V  ER+
Sbjct: 361 IGTYLPSAMLLGANFTIMSILMWFKSGQPEEEEEPEGQEAATNSGASVTSESRPVV-ERE 419

Query: 421 LFLPLVLVAVCQFLGVVPLYLFNHLS 446
           L +PL ++  C FLG VPLY+FNHL 
Sbjct: 420 LLVPLSVIGTCLFLGAVPLYMFNHLP 445
>ref|XP_235447.2| similar to glycosylphosphatidylinositol anchor attachment 1 (GPAA1)
           [Rattus norvegicus]
          Length = 619

 Score =  555 bits (1416), Expect = e-156
 Identities = 157/477 (32%), Positives = 234/477 (48%), Gaps = 44/477 (9%)

Query: 4   LLASALSLRRDPRL-LKLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQVHT 62
           LL+  +  R   R+ L+L   L +L  V G+ W   L     ++RTY+SENA+    V  
Sbjct: 3   LLSDPVRRRALARIVLRLNTPLCVLSYVAGIAWFLALAFPPLTQRTYMSENAMGSTMVEE 62

Query: 63  YFGGSDQNVFRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNFT--YSSAGNTH- 119
            F G D+    A          K        LE   + +GL+V  Q+F+        TH 
Sbjct: 63  QFVGGDRARNFARDFAAH--RKKPGALPVAWLERAMRSVGLEVYTQSFSRKLPFPDETHE 120

Query: 120 ----SGQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSK 175
               SG N+Y IL+APR  +TE++VL           N   V L+L LA +F+    W+K
Sbjct: 121 RYMVSGTNVYGILRAPRAASTESLVLTVPCG--PDTTNSQAVGLLLALAAHFRGQIYWAK 178

Query: 176 DIIFLFTPDSIAGPQAWVDAYHDAHDSSRVAS-LPLKSGALQGAIALDYTRETRFQSVHI 234
           DIIFL T   + G +AW++AYHD + +   +S L  ++GA+Q A+AL+ + +    S+ +
Sbjct: 179 DIIFLVTEHDLLGTEAWLEAYHDINVTGIQSSPLQGRAGAIQAAVALELSSDV-VTSLDV 237

Query: 235 VYDGVNGQLPNLDLINSVNHVA--GGQMGMGVAIQEMWKHSNSYHDRLQTMLRGMLKQGL 292
             +G+NGQLPNLDL+N        GG +       + W         LQT+L  +L+Q  
Sbjct: 238 TVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKPQDWTSLEGPLQGLQTLLLMVLRQAS 297

Query: 293 GLASGPHSSFIPYHVDAVTLQ---PFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQSFFF 349
           G   GPH  F+ Y V+A+TL+    F +   D +A+G+ +EG FR LN+LLE LHQSFFF
Sbjct: 298 GRPHGPHGLFLRYGVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSFFF 357

Query: 350 YLLMQRERFVSIGTYLPSAMLVAANFTIMAIALWVKSGQPDVQEIITEKTKTAEEAERIV 409
           YLL    RFVSIG Y+P+   +     + A+ LW++           E     EEA +  
Sbjct: 358 YLLPALSRFVSIGLYMPATGFLLLVLGLKALELWMQL---------HEAGVNPEEAGKAP 408

Query: 410 SP-NPHV----ASERDLFLPLVLVAVCQFLGVVPLYL--------FNHLSESASSAL 453
            P +P +     S   L  PL+   + Q +G+   +L          H   + + A+
Sbjct: 409 GPGSPPLATQSVSLASLMAPLL---ISQAMGLALYFLPVLGQHVAAQHFPVAEAEAV 462
>ref|NP_034461.1| GPI anchor attachment protein 1 [Mus musculus]
 dbj|BAA82589.1| glycosylphosphatidylinositol anchor attachment 1 (GPAA1) [Mus
           musculus]
 dbj|BAA82591.1| glycosylphosphatidylinositol anchor attachment 1 (GPAA1) [Mus
           musculus]
 dbj|BAB03274.1| GPI anchor attachment protein [Mus musculus]
 dbj|BAB03275.1| GPI anchor attachment protein [Mus musculus]
 gb|AAH06697.1| GPI anchor attachment protein 1 [Mus musculus]
 dbj|BAC36840.1| unnamed protein product [Mus musculus]
          Length = 621

 Score =  550 bits (1404), Expect = e-155
 Identities = 155/479 (32%), Positives = 231/479 (47%), Gaps = 46/479 (9%)

Query: 4   LLASALSLRRDPRL-LKLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQVHT 62
           LL+  +  R   R+ L+L   L +L  V G+ W   L     ++RTY+SENA+    V  
Sbjct: 3   LLSDPVRRRALARIVLRLNTPLCVLSYVAGIAWFLALAFPPLTQRTYMSENAMGSTMVEE 62

Query: 63  YFGGSDQNVFRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNFT--YSSAGNTH- 119
            F G D+    A          K        LE   + +GL+V  Q+F+        TH 
Sbjct: 63  QFVGGDRARSFARDFAAH--RKKPGALPVAWLERSMRSVGLEVYTQSFSRKLPFPDETHE 120

Query: 120 ----SGQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSK 175
               SG N+Y IL+APR  +TE++VL           N   V L+L LA +F+    W+K
Sbjct: 121 RYMVSGTNVYGILRAPRSASTESLVLTVPCG--PDATNSQAVGLLLALAAHFRGQIYWAK 178

Query: 176 DIIFLFTPDSIAGPQAWVDAYHDAHDSSRVAS-LPLKSGALQGAIALDYTRETRFQSVHI 234
           DIIFL T   + G +AW++AYHD + +   +S L  ++GA+Q A+AL+ + +    S+ +
Sbjct: 179 DIIFLVTDHDLLGTEAWLEAYHDINVTGIQSSPLQGRAGAIQAAVALELSSDV-VTSLDV 237

Query: 235 VYDGVNGQLPNLDLINSVNHVA--GGQMG--MGVAIQEMWKHSNSYHDRLQTMLRGMLKQ 290
             +G+NGQLPNLDL+N        GG +    G    + W         LQT+L  +L+Q
Sbjct: 238 TVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPQDWTSLEGPLQGLQTLLLMVLRQ 297

Query: 291 GLGLASGPHSSFIPYHVDAVTLQ---PFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQSF 347
             G   GPH  F+ Y V+A+TL+    F +   D   +G+ +EG FR LN+LLE LHQSF
Sbjct: 298 ASGRPHGPHGLFLRYGVEALTLRGINSFRQYKYDLATVGKALEGMFRKLNHLLERLHQSF 357

Query: 348 FFYLLMQRERFVSIGTYLPSAMLVAANFTIMAIALWVKSGQPDVQEIITEKTKTAEEAER 407
           FFYLL    RFVSIG Y+P+   +     + A+ LW++           +     EEA +
Sbjct: 358 FFYLLPALSRFVSIGLYMPATGFLLLVLGLKALELWMQL---------HQAGVNPEEAGK 408

Query: 408 IVSPNPHV-----ASERDLFLPLVLVAVCQFLGVVPLYL--------FNHLSESASSAL 453
             SP   +          L  PL+   + Q +G+   +L          H   + + A+
Sbjct: 409 APSPGTPLLPTQGVGLASLTAPLL---ISQAMGLALYFLPVLGQHLATQHFPVAEAEAV 464
>ref|NP_003792.1| anchor attachment protein 1; glycophosphatidylinositol anchor
           attachment 1; anchor attachment protein 1 (Gaa1p, yeast)
           homolog [Homo sapiens]
 dbj|BAA24035.1| hGAA1 [Homo sapiens]
 dbj|BAA82588.1| glycosylphosphatidylinositol anchor attachment 1 (GPAA1) [Homo
           sapiens]
 dbj|BAA82590.1| glycosylphosphatidylinositol anchor attachment 1 (GPAA1) [Homo
           sapiens]
 gb|AAH03171.1| Anchor attachment protein 1 [Homo sapiens]
 gb|AAH04129.1| Anchor attachment protein 1 [Homo sapiens]
          Length = 621

 Score =  533 bits (1361), Expect = e-150
 Identities = 154/479 (32%), Positives = 230/479 (47%), Gaps = 46/479 (9%)

Query: 4   LLASALSLRRDPRL-LKLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQVHT 62
           LL+  +  R   RL L+L   L +L  V G+ W   L     ++RTY+SENA+    V  
Sbjct: 3   LLSDPVRRRALARLVLRLNAPLCVLSYVAGIAWFLALVFPPLTQRTYMSENAMGSTMVEE 62

Query: 63  YFGGSDQNVFRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNFT--YSSAGNTH- 119
            F G D+    A          K        LE   + +GL+V  Q+F+        TH 
Sbjct: 63  QFAGGDRARAFARDFAAH--RKKSGALPVAWLERTMRSVGLEVYTQSFSRKLPFPDETHE 120

Query: 120 ----SGQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSK 175
               SG N+Y IL+APR  +TE++VL     +     N   V L+L LA +F+    W+K
Sbjct: 121 RYMVSGTNVYGILRAPRAASTESLVLTVPCGS--DSTNSQAVGLLLALAAHFRGQIYWAK 178

Query: 176 DIIFLFTPDSIAGPQAWVDAYHDAHDSSRVAS-LPLKSGALQGAIALDYTRETRFQSVHI 234
           DI+FL T   + G +AW++AYHD + +   +S L  ++GA+Q A+AL+ + +    S+ +
Sbjct: 179 DIVFLVTEHDLLGTEAWLEAYHDVNVTGMQSSPLQGRAGAIQAAVALELSSDV-VTSLDV 237

Query: 235 VYDGVNGQLPNLDLINSVNHVA--GGQMG--MGVAIQEMWKHSNSYHDRLQTMLRGMLKQ 290
             +G+NGQLPNLDL+N        GG +    G    E W   +     LQT+L  +L+Q
Sbjct: 238 AVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPEDWTSLDGPLQGLQTLLLMVLRQ 297

Query: 291 GLGLASGPHSSFIPYHVDAVTLQ---PFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQSF 347
             G   G H  F+ Y V+A+TL+    F +   D +A+G+ +EG FR LN+LLE LHQSF
Sbjct: 298 ASGRPHGSHGLFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSF 357

Query: 348 FFYLLMQRERFVSIGTYLPSAMLVAANFTIMAIALWVKSGQPDVQEIITEKTKTAEEAER 407
           F YLL    RFVSIG Y+P+   +     + A+ LW++           E     EE   
Sbjct: 358 FLYLLPGLSRFVSIGLYMPAVGFLLLVLGLKALELWMQL---------HEAGMGLEEPGG 408

Query: 408 IVSPNPHV-----ASERDLFLPLVLVAVCQFLGVVPLYL--------FNHLSESASSAL 453
              P+  +          L  PL+   + Q +G+    L          H   + + A+
Sbjct: 409 APGPSVPLPPSQGVGLASLVAPLL---ISQAMGLALYVLPVLGQHVATQHFPVAEAEAV 464
>gb|AAH60413.1| Unknown (protein for MGC:68658) [Xenopus laevis]
          Length = 615

 Score =  519 bits (1325), Expect = e-146
 Identities = 154/475 (32%), Positives = 239/475 (49%), Gaps = 44/475 (9%)

Query: 4   LLASALSLRRDPRLL-KLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQVHT 62
           LL+     +   R++ +L   L +   ++GVVW   L    ++ R+YISEN++    V  
Sbjct: 3   LLSDPNRRQALSRIITQLNTPLCIFSYLVGVVWFLGLAFHPFTLRSYISENSMGSTMVEE 62

Query: 63  YFGGSDQNVFRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNF--TYSSAGNTH- 119
            F   ++ V  A +    + +  G+      LE    GLGL+V  Q+F  T      T  
Sbjct: 63  QFVSGERAVSYAREFAAHKKSAGGS--PVAWLERTMSGLGLEVYSQSFVRTLPFPDETTE 120

Query: 120 ----SGQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSK 175
                G N+Y IL+APR  +TE++VL       +G+ N   V L+L LA YF+    W+K
Sbjct: 121 RFMVKGTNVYGILRAPRAASTESLVLSVPC--SEGQNNNQAVGLLLALASYFRGQIYWAK 178

Query: 176 DIIFLFTPDSIAGPQAWVDAYHDAHDSSRVASLPL-KSGALQGAIALDYTRETRFQSVHI 234
           DIIFL     + G +AW++ YHD + +   +S+ + ++GA+Q A++L+ + +    S  +
Sbjct: 179 DIIFLVNEHDLIGMEAWLEGYHDVNVTEIKSSVMIGRAGAIQAAVSLEMSSDV-VTSFDL 237

Query: 235 VYDGVNGQLPNLDLINSVNHVAGGQMGMGVAIQEMWKHSN-----SYHDRLQTMLRGMLK 289
           V +G+NGQLPNLDL++   +    +  +   IQ   + ++      Y   LQTML  +LK
Sbjct: 238 VVEGLNGQLPNLDLVSLF-YAFCQKNALLCTIQGKLQRNDFDTFPGYLHSLQTMLIMVLK 296

Query: 290 QGLGLASGPHSSFIPYHVDAVTLQ---PFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQS 346
           QG G   G H  F+ YH++A+TL+    F +   D   +G+ +EG FR LNNL E LHQS
Sbjct: 297 QGAGRPQGDHGLFLRYHIEAITLRGINSFRQYKYDLSTVGKTLEGMFRKLNNLSERLHQS 356

Query: 347 FFFYLLMQRERFVSIGTYLPSAMLVAANFTIMAIALWVKSGQPDVQEIITEKTKTAEEAE 406
           +FFYLL    RFVSIG Y+P+   +     + ++ LW+K    D +   TE      E +
Sbjct: 357 YFFYLLPCLSRFVSIGIYMPAVGFIILILILRSLDLWIKLRHSDGR---TEDGVMDTEQD 413

Query: 407 RIVSPNPHVASERDLFLPLVLVAVCQFLGVVPLYL--------FNHLSESASSAL 453
               P P +     L  P+V   +C   G+   YL         +H   S S A+
Sbjct: 414 ----PRPGIL---SLATPIV---ICHATGLSLYYLPVMSQEMATDHFPVSESEAV 458
>gb|AAH06383.2| GPAA1 protein [Homo sapiens]
          Length = 561

 Score =  454 bits (1157), Expect = e-126
 Identities = 133/415 (32%), Positives = 199/415 (47%), Gaps = 43/415 (10%)

Query: 67  SDQNVFRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNFT--YSSAGNTH----- 119
           SD    RA       L           LE   + +GL+V  Q+F+        TH     
Sbjct: 5   SDPVRRRALARLVLRLNAPLWALPVAWLERTMRSVGLEVYTQSFSRKLPFPDETHERYMV 64

Query: 120 SGQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSKDIIF 179
           SG N+Y IL+APR  +TE++VL     +     N   V L+L LA +F+    W+KDI+F
Sbjct: 65  SGTNVYGILRAPRAASTESLVLTVPCGS--DSTNSQAVGLLLALAAHFRGQIYWAKDIVF 122

Query: 180 LFTPDSIAGPQAWVDAYHDAHDSSRVAS-LPLKSGALQGAIALDYTRETRFQSVHIVYDG 238
           L T   + G +AW++AYHD + +   +S L  ++GA+Q A+AL+ + +    S+ +  +G
Sbjct: 123 LVTEHDLLGTEAWLEAYHDVNVTGMQSSPLQGRAGAIQAAVALELSSDV-VTSLDVAVEG 181

Query: 239 VNGQLPNLDLINSVNHVA--GGQMG--MGVAIQEMWKHSNSYHDRLQTMLRGMLKQGLGL 294
           +NGQLPNLDL+N        GG +    G    E W   +     LQT+L  +L+Q  G 
Sbjct: 182 LNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPEDWTSLDGPLQGLQTLLLMVLRQASGR 241

Query: 295 ASGPHSSFIPYHVDAVTLQ---PFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQSFFFYL 351
             G H  F+ Y V+A+TL+    F +   D +A+G+ +EG FR LN+LLE LHQSFF YL
Sbjct: 242 PHGSHGLFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSFFLYL 301

Query: 352 LMQRERFVSIGTYLPSAMLVAANFTIMAIALWVKSGQPDVQEIITEKTKTAEEAERIVSP 411
           L    RFVSIG Y+P+   +     + A+ LW++           E     EE      P
Sbjct: 302 LPGLSRFVSIGLYMPAVGFLLLVLGLKALELWMQL---------HEAGMGLEEPGGAPGP 352

Query: 412 NPHV-----ASERDLFLPLVLVAVCQFLGVVPLYL--------FNHLSESASSAL 453
           +  +          L  PL+   + Q +G+    L          H   + + A+
Sbjct: 353 SVPLPPSQGVGLASLVAPLL---ISQAMGLALYVLPVLGQHVATQHFPVAEAEAV 404
>ref|NP_572273.2| CG3033-PA [Drosophila melanogaster]
 gb|AAF46094.1| CG3033-PA [Drosophila melanogaster]
          Length = 674

 Score =  452 bits (1152), Expect = e-126
 Identities = 136/480 (28%), Positives = 226/480 (46%), Gaps = 48/480 (10%)

Query: 4   LLASALSLRRDPRLL----KLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQ 59
           LL+   S+    +L+    +    +     V GV W F L L +++  TY+SENAL PG 
Sbjct: 3   LLSDP-SISTQSKLVDGLARHVRKVCYALYVAGVAWFFCLALPEFNHGTYLSENALSPGL 61

Query: 60  VHTYFGGSDQNVFRAYKHETDELAGKGN--IEVNDKLESIAKGLGLKVGRQNFTYSSA-- 115
           V+      D N       E  +   K +     +  + +     GL+    N+T      
Sbjct: 62  VYPEIR-IDANRLAIQLLEELQRERKDHLSTTPHAWIAAKMNEFGLETHTHNYTLRYPFG 120

Query: 116 -GNTHSGQNIYAILQAPRGDATEAIVLVAAWK---NVKGELNRSGVPLVLTLARYFKRWS 171
            G  + G+NIY IL+APR  +TE IV  A ++   +V  +++ + VPL+L  A + +R +
Sbjct: 121 GGKEYHGKNIYGILRAPRIASTEGIVFAAPYRAASSVHTDIS-ASVPLLLAFADFARRKN 179

Query: 172 LWSKDIIFLFTPDSIAGPQAWVDAYHDAHDS-------SRVASLPLKSGALQGAIALDYT 224
            W+KD+IFL T     G QAW++AYHD            R  +LP ++G+LQ A+ ++  
Sbjct: 180 YWAKDLIFLITEQEQLGMQAWLEAYHDGDRELDLSKAYLRPGNLPARAGSLQAALNIEV- 238

Query: 225 RETRFQSVHIVYDGVNGQLPNLDLINSVNHV---AGGQMGMGVAIQEMWKHSNSYHDR-L 280
           ++     V +  +G+NG+LPNLD+ N V  +    G   G   A ++  +HS S+ ++  
Sbjct: 239 QDLEIDHVDVRIEGLNGKLPNLDMFNLVQRIMAREGIASGYKQAPRKKRRHSQSHFEQNF 298

Query: 281 QTMLRGMLKQGLGLASGPHSSFIPYHVDAVTLQPFGE---------GWQDEMAIGRVIEG 331
           + ML  +  Q  G+ +G H  F  Y +DA+T+                   + + + IEG
Sbjct: 299 RQMLTMLASQSSGVPTGNHGLFHRYRIDALTIAANRRATHATLKGSPGSAAVPLLKAIEG 358

Query: 332 TFRSLNNLLEHLHQSFFFYLLMQRERFVSIGTYLPSAMLVAANFTIMAIALWVKSGQPDV 391
             RSLNNLLE  HQSFFFY+++  +R++SIG Y+P+ + + A   + A   W      + 
Sbjct: 359 IARSLNNLLERFHQSFFFYVIVSNDRYISIGDYMPALVALVACAFLKAYLTWSTLPATNA 418

Query: 392 QEII----------TEKTKTAEEAERIVSPNPHVASERDLFLPLVLVAVCQFLGVVPLYL 441
           +               + +   E ++   P   V     L   L++  +C  L +   +L
Sbjct: 419 ELEKAAGWLREHEQEAELEENLEPDKFELPYGSVLIY--LTATLLIGFLCNVLPLQQYFL 476
>gb|AAK77275.1| GH05723p [Drosophila melanogaster]
          Length = 561

 Score =  452 bits (1151), Expect = e-125
 Identities = 136/480 (28%), Positives = 226/480 (46%), Gaps = 48/480 (10%)

Query: 4   LLASALSLRRDPRLL----KLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQ 59
           LL+   S+    +L+    +    +     V GV W F L L +++  TY+SENAL PG 
Sbjct: 3   LLSDP-SISTQSKLVDGLARHVRKVCYALYVAGVAWFFCLALPEFNHGTYLSENALSPGL 61

Query: 60  VHTYFGGSDQNVFRAYKHETDELAGKGN--IEVNDKLESIAKGLGLKVGRQNFTYSSA-- 115
           V+      D N       E  +   K +     +  + +     GL+    N+T      
Sbjct: 62  VYPEIR-IDANRLAIQLLEELQRERKDHLSTTPHAWIAAKMNEFGLETHTHNYTLRYPFG 120

Query: 116 -GNTHSGQNIYAILQAPRGDATEAIVLVAAWK---NVKGELNRSGVPLVLTLARYFKRWS 171
            G  + G+NIY IL+APR  +TE IV  A ++   +V  +++ + VPL+L  A + +R +
Sbjct: 121 GGKEYHGKNIYGILRAPRIASTEGIVFAAPYRAASSVHTDIS-ASVPLLLAFADFARRKN 179

Query: 172 LWSKDIIFLFTPDSIAGPQAWVDAYHDAHDS-------SRVASLPLKSGALQGAIALDYT 224
            W+KD+IFL T     G QAW++AYHD            R  +LP ++G+LQ A+ ++  
Sbjct: 180 YWAKDLIFLITEQEQLGMQAWLEAYHDGDRELDLSKAYLRPGNLPARAGSLQAALNIEV- 238

Query: 225 RETRFQSVHIVYDGVNGQLPNLDLINSVNHV---AGGQMGMGVAIQEMWKHSNSYHDR-L 280
           ++     V +  +G+NG+LPNLD+ N V  +    G   G   A ++  +HS S+ ++  
Sbjct: 239 QDLEIDHVDVRIEGLNGKLPNLDMFNLVQRIMAREGIASGYKQAPRKKRRHSQSHFEQNF 298

Query: 281 QTMLRGMLKQGLGLASGPHSSFIPYHVDAVTLQPFGE---------GWQDEMAIGRVIEG 331
           + ML  +  Q  G+ +G H  F  Y +DA+T+                   + + + IEG
Sbjct: 299 RQMLTMLASQSSGVPTGNHGLFHRYRIDALTIAANRRATHATLKGSPGSAAVPLLKAIEG 358

Query: 332 TFRSLNNLLEHLHQSFFFYLLMQRERFVSIGTYLPSAMLVAANFTIMAIALWVKSGQPDV 391
             RSLNNLLE  HQSFFFY+++  +R++SIG Y+P+ + + A   + A   W      + 
Sbjct: 359 IARSLNNLLERFHQSFFFYVIVSNDRYISIGDYMPALVALVACAFLKAYLTWSTLPATNA 418

Query: 392 QEII----------TEKTKTAEEAERIVSPNPHVASERDLFLPLVLVAVCQFLGVVPLYL 441
           +               + +   E ++   P   V     L   L++  +C  L +   +L
Sbjct: 419 ELEKAAGWLREHEQEAELEENLEPDKFELPYGSVLIY--LTATLLIGFLCNVLPLQQYFL 476
>ref|XP_311451.1| ENSANGP00000018454 [Anopheles gambiae]
 gb|EAA07058.1| ENSANGP00000018454 [Anopheles gambiae str. PEST]
          Length = 647

 Score =  448 bits (1143), Expect = e-124
 Identities = 133/405 (32%), Positives = 209/405 (50%), Gaps = 21/405 (5%)

Query: 16  RLLKLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQVHTYFGGSDQNVFRAY 75
           +L++    + L   ++GV +   LP  +++  TY SENALLPG V++       N+ ++ 
Sbjct: 21  KLVRYNTAICLTLYLLGVGFFCALPDANFNSGTYFSENALLPGLVNSELEMETVNLVKSL 80

Query: 76  KHETD-ELAGKGNIEVNDKLESIAKGLGLKVGRQNFTYSSA---GNTHSGQNIYAILQAP 131
             E   E            L +  +  GL+    NFT +     G    G+N+Y IL+AP
Sbjct: 81  SSELQRERENYPKGMPYPWLLAKMRRFGLETHTHNFTLNYPFGGGKRFKGENVYGILRAP 140

Query: 132 RGDATEAIVLVAAWK---NVKGELNRSGVPLVLTLARYFKRWSLWSKDIIFLFTPDSIAG 188
           R  +TEAIV+   ++    V  +++ +GVPL+L  A + +R   W+KDIIFL T     G
Sbjct: 141 RIASTEAIVISVPYRPPETVHTDVS-AGVPLMLAFADFARRKKYWAKDIIFLVTEQEQLG 199

Query: 189 PQAWVDAYHDAHDSSRVAS---LPLKSGALQGAIALDYTRETRFQSVHIVYDGVNGQLPN 245
            QAW++AYH   D  R+     L  ++G++Q A+ L+  +      +++  +G+NGQLPN
Sbjct: 200 MQAWLEAYHGG-DEGRILDSGLLRARAGSIQAALNLEV-QSLDISHINLKIEGLNGQLPN 257

Query: 246 LDLINSVNHVAGGQ--MGMGVAIQEMWKHSNSYHDRLQTMLRGMLKQGLGLASGPHSSFI 303
           LDL N V  ++     +          K S  Y D+L  +L  +  Q  G+ +G H  F 
Sbjct: 258 LDLHNLVQKLSSKNGIIAGYKQSSSSPKRSFRYQDKLLNLLSMVFSQASGVPTGNHGLFH 317

Query: 304 PYHVDAVTLQPFG------EGWQDEMAIGRVIEGTFRSLNNLLEHLHQSFFFYLLMQRER 357
            Y ++A+TL+         + +Q+  ++ R+IEG  RSLNNLLE  HQSFFFYLL+  +R
Sbjct: 318 KYGIEALTLEAVKRERTQQQQFQEVGSMLRIIEGICRSLNNLLERFHQSFFFYLLVSNDR 377

Query: 358 FVSIGTYLPSAMLVAANFTIMAIALWVKSGQPDVQEIITEKTKTA 402
           FVSIG Y+PS  L+A    I A   ++        +   +  +T 
Sbjct: 378 FVSIGDYMPSLALMAGALLIKAFIHYLSLYYTGDNDETEKSEETD 422
>ref|NP_593498.1| putative glycosylphosphatidylinositol anchor attachment protein
           [Schizosaccharomyces pombe]
 emb|CAB65611.1| SPAC1002.11 [Schizosaccharomyces pombe]
          Length = 581

 Score =  448 bits (1141), Expect = e-124
 Identities = 143/393 (36%), Positives = 228/393 (57%), Gaps = 13/393 (3%)

Query: 5   LASALSLRRDPRLLKLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQVHTYF 64
           L + + +R  P L +   +L L   +IG+ W+F+LP ++   R ++SE+ALLPGQV+TYF
Sbjct: 3   LFTFVQIRVFPFLQRHLFFLQLSLTLIGLSWIFILPRNEIIDRLHVSESALLPGQVNTYF 62

Query: 65  ----GGSDQNVFRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNFTYSSAGNTHS 120
                 +  +   A    +   A  G   + D LE I   +GL   +QN++ +  G+  +
Sbjct: 63  ENRYSKTVSSSLTAANTWSHLDASVGTNTMYDDLEQIFTAMGLPTQKQNYSINIPGSEFN 122

Query: 121 GQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSKDIIFL 180
           G N    L+APRGDATE+++L   WK+  G+ N +GV L ++L +YF+ WSLWSKDII +
Sbjct: 123 GSNFITTLRAPRGDATESLLLCVPWKDHIGQYNEAGVALAISLLKYFQGWSLWSKDIILV 182

Query: 181 FTPDSIAGPQAWVDAYHDAHDSSRVASLP--LKSGALQGAIALDY-TRETRFQSVHIVYD 237
              D + GP +++ +Y D   +  ++  P  ++SG++Q  ++L+  T E     + ++Y 
Sbjct: 183 IFDDPVYGPSSFLTSYFD-QTTPYISYTPLKIRSGSIQAGLSLELVTTENNSDVLEVLYQ 241

Query: 238 GVNGQLPNLDLINSVNHVAGGQMGMGVAIQEMWKHSN---SYHDRLQTMLRGMLKQGLGL 294
             NGQLPNLDL N+++ +        + +Q    H+N   SY  RL+++  GML Q +  
Sbjct: 242 ATNGQLPNLDLFNTISRIFMQHFNYPLRLQGYDFHANSGSSYTSRLKSLWMGMLTQAVSN 301

Query: 295 ASGPHSSFIPYHVDAVTLQ-PFGEGW-QDEMAIGRVIEGTFRSLNNLLEHLHQSFFFYLL 352
            +  H+ F  Y +D +TL+    + +  D    G+ IE TFRSLNNLLEHLHQSFFFY +
Sbjct: 302 VTSAHALFPQYRIDMLTLRMKVKDPFSFDMFRFGQAIESTFRSLNNLLEHLHQSFFFYFI 361

Query: 353 MQRERFVSIGTYLPSAMLVAANFTIMAIALWVK 385
           +    F+SIG Y+PS +++AA+F + A   W+ 
Sbjct: 362 LDHLHFISIGNYMPSILILAASFMLGAYRHWIN 394
>ref|NP_013189.1| ER protein essential for attaching GPI
           (glycosylphosphatidylinositol) to protein; Gaa1p
           [Saccharomyces cerevisiae]
 sp|P39012|GAA1_YEAST GAA1 protein
 pir||S45053 membrane protein END2 - yeast (Saccharomyces cerevisiae)
 emb|CAA55944.1| Gaa1 [Saccharomyces cerevisiae]
 gb|AAB67592.1| Gaa1p [Saccharomyces cerevisiae]
 emb|CAA97649.1| GAA1 [Saccharomyces cerevisiae]
          Length = 614

 Score =  433 bits (1102), Expect = e-120
 Identities = 146/398 (36%), Positives = 224/398 (55%), Gaps = 26/398 (6%)

Query: 4   LLASALSLRRD----PRLLKLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQ 59
           LL        D    PR++ L P +S+LC + G + + +LP+D   RRTYISENAL+P Q
Sbjct: 3   LLEKLHRRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMPSQ 62

Query: 60  VHTYFGGSDQNVFRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNFTYSSAGNTH 119
            ++YF  S+ N+ R Y+ +  E+    ++E N+ + S  +  G K            N  
Sbjct: 63  AYSYFRESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTKTAIYE-------NEQ 115

Query: 120 SGQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSKDIIF 179
            G+ +Y ++ APRGD TEA+VL   W N   E N  G  L ++LAR+F RW +WSK+II 
Sbjct: 116 YGETLYGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLARFFSRWPVWSKNIIV 175

Query: 180 LFTPDSIAGPQAWVDAYHDAHDSSRVASLPLKSGALQGAIALDYTR-ETRFQSVHIVYDG 238
           +F+ +  A  ++WV+AYH         SL L  G+++ A+ LDY+  E  F+ V I YDG
Sbjct: 176 VFSENPRAALRSWVEAYH--------TSLDLTGGSIEAAVVLDYSSTEDFFEYVEISYDG 227

Query: 239 VNGQLPNLDLINSVNHVAGGQMGMGVAIQEMWK---HSNSYHDRLQTMLRGMLKQGLGLA 295
           +NG+LPNLDL+N    +   + GM V++  +      +N++  RL+ +  G+    L   
Sbjct: 228 LNGELPNLDLVNIAISITEHE-GMKVSLHGLPSDQLTNNNFWSRLKILCLGIRDWALSGV 286

Query: 296 SGPHS--SFIPYHVDAVTLQPFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQSFFFYLLM 353
             PH   +F  + + +VTL+  G    D    GR+ E  FRS+NNLLE  HQSFFFYLL+
Sbjct: 287 KKPHGNEAFSGWRIQSVTLKAHGNSGHDITTFGRIPEAMFRSINNLLEKFHQSFFFYLLL 346

Query: 354 QRERFVSIGTYLPSAMLVAANFTIMAIALWVKSGQPDV 391
              +FVSI +YLPSA+ ++  F I ++  ++ +   ++
Sbjct: 347 APRQFVSISSYLPSAVALSIAFAISSLNAFINNAYANI 384
>pir||T46923 hypothetical protein DKFZp434E1512.1 - human
 emb|CAB75660.1| hypothetical protein [Homo sapiens]
          Length = 499

 Score =  410 bits (1043), Expect = e-113
 Identities = 119/355 (33%), Positives = 180/355 (50%), Gaps = 36/355 (10%)

Query: 120 SGQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSKDIIF 179
           SG N+Y IL+APR  +TE++VL     +     N   V L+L LA +F+    W+KDI+F
Sbjct: 3   SGTNVYGILRAPRAASTESLVLTVPCGS--DSTNSQAVGLLLALAAHFRGQIYWAKDIVF 60

Query: 180 LFTPDSIAGPQAWVDAYHDAHDSSRVAS-LPLKSGALQGAIALDYTRETRFQSVHIVYDG 238
           L T   + G +AW++AYHD + +   +S L  ++GA+Q A+AL+ + +    S+ +  +G
Sbjct: 61  LVTEHDLLGTEAWLEAYHDVNVTGMQSSPLQGRAGAIQAAVALELSSDV-VTSLDVAVEG 119

Query: 239 VNGQLPNLDLINSVNHVA--GGQMG--MGVAIQEMWKHSNSYHDRLQTMLRGMLKQGLGL 294
           +NGQLPNLDL+N        GG +    G    E W   +     LQT+L  +L+Q  G 
Sbjct: 120 LNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPEDWTSLDGPLQGLQTLLLMVLRQASGR 179

Query: 295 ASGPHSSFIPYHVDAVTLQ---PFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQSFFFYL 351
             G H  F+ Y V+A+TL+    F +   D +A+G+ +EG FR LN+LLE LHQSFF YL
Sbjct: 180 PHGSHGLFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSFFLYL 239

Query: 352 LMQRERFVSIGTYLPSAMLVAANFTIMAIALWVKSGQPDVQEIITEKTKTAEEAERIVSP 411
           L    RFVSIG Y+P+   +     + A+ LW++           E     EE      P
Sbjct: 240 LPGLSRFVSIGLYMPAVGFLLLVLGLKALELWMQL---------HEAGMGLEEPGGAPGP 290

Query: 412 NPHV-----ASERDLFLPLVLVAVCQFLGVVPLYL--------FNHLSESASSAL 453
           +  +          L  PL+   + Q +G+    L          H   + + A+
Sbjct: 291 SVPLPPSQGVGLASLVAPLL---ISQAMGLALYVLPVLGQHVATQHFPVAEAEAV 342
>pir||T32771 hypothetical protein F33D11.9b - Caenorhabditis elegans
          Length = 885

 Score =  394 bits (1004), Expect = e-108
 Identities = 115/416 (27%), Positives = 189/416 (44%), Gaps = 44/416 (10%)

Query: 3   RLLASALSLRRD-----PRLL-------KLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYI 50
           +LL  AL + +D     P++L       K+   ++ +   +   WLF  P++     T I
Sbjct: 275 KLLEMALEISKDGGTTRPKILDKILKFRKVALIIAYIGAYLSAQWLF-DPVN--MEVTRI 331

Query: 51  SENALLPGQVHTYFGGSDQNVFRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNF 110
           SE++L+PG V   F  S   + + Y+  +D    K   E+   + +I   LGL+     +
Sbjct: 332 SEHSLMPGLVTPKFDKSGIAI-QLYRRFSDLPKSKSQQEL---IHTIFSDLGLECFTHKW 387

Query: 111 TYSSAGNTHSGQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRW 170
               AGN  +G+N+Y  ++ PR D  EA ++V      + E +R  +  +L    Y K  
Sbjct: 388 RSKVAGNPMNGENVYGFIRGPRNDGAEAQMIVVQLG--RSEKSRRMMSRMLAFVDYAKDQ 445

Query: 171 SLWSKDIIFLFT-----PDSIAGPQAWVDAYH------DAHDSSRVAS-----LPLKSGA 214
             W++DI+ +F       DSI      +DA+       +A +S +  +     +  ++GA
Sbjct: 446 VYWARDIVIVFVDGGEKNDSIEKAAFALDAFLLKYQKIEALNSKKSITVEADEIQAQTGA 505

Query: 215 LQGAIALDYT-RETRFQS-VHIVYDGVNGQLPNLDLINSVNHVAGGQMGMGVAI-QEMWK 271
           L G +  D +    + Q  V+I  +G+NGQ  NLD+ N +  +A  +    VAI   + +
Sbjct: 506 LIGGVVYDLSGMAVKGQHIVNIQTNGLNGQQVNLDVFNGITKIADSKHHSRVAIFGTLHR 565

Query: 272 HSNSY--HDRLQTMLRGMLKQGLGLASGPHSSFIPYHVDAVTLQPFGEGWQDEMAIGRVI 329
           HSN Y  +      +R +  Q      G HS    Y V  +T+    +    E   G+ I
Sbjct: 566 HSNPYMEYSPFIVPMRALYTQAFISIEGIHSVLGKYGVQGLTVGLSHD--YSEKQTGQFI 623

Query: 330 EGTFRSLNNLLEHLHQSFFFYLLMQRERFVSIGTYLPSAMLVAANFTIMAIALWVK 385
           E   R LNN+LE LHQS+F Y+L     F SI  Y+    ++ +   I A   W K
Sbjct: 624 EEVSRMLNNVLERLHQSYFMYVLADDLHFSSIAMYIIPLTILVSPLVISAYFEWTK 679
>ref|NP_491700.2| anchor attachment protein 1 (1G434) [Caenorhabditis elegans]
 gb|AAK68360.2| Hypothetical protein F33D11.9b [Caenorhabditis elegans]
          Length = 676

 Score =  390 bits (993), Expect = e-107
 Identities = 115/416 (27%), Positives = 189/416 (44%), Gaps = 44/416 (10%)

Query: 3   RLLASALSLRRD-----PRLL-------KLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYI 50
           +LL  AL + +D     P++L       K+   ++ +   +   WLF  P++     T I
Sbjct: 13  KLLEMALEISKDGGTTRPKILDKILKFRKVALIIAYIGAYLSAQWLF-DPVN--MEVTRI 69

Query: 51  SENALLPGQVHTYFGGSDQNVFRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNF 110
           SE++L+PG V   F  S   + + Y+  +D    K   E+   + +I   LGL+     +
Sbjct: 70  SEHSLMPGLVTPKFDKSGIAI-QLYRRFSDLPKSKSQQEL---IHTIFSDLGLECFTHKW 125

Query: 111 TYSSAGNTHSGQNIYAILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRW 170
               AGN  +G+N+Y  ++ PR D  EA ++V      + E +R  +  +L    Y K  
Sbjct: 126 RSKVAGNPMNGENVYGFIRGPRNDGAEAQMIVVQLG--RSEKSRRMMSRMLAFVDYAKDQ 183

Query: 171 SLWSKDIIFLFT-----PDSIAGPQAWVDAYH------DAHDSSRVAS-----LPLKSGA 214
             W++DI+ +F       DSI      +DA+       +A +S +  +     +  ++GA
Sbjct: 184 VYWARDIVIVFVDGGEKNDSIEKAAFALDAFLLKYQKIEALNSKKSITVEADEIQAQTGA 243

Query: 215 LQGAIALDYT-RETRFQS-VHIVYDGVNGQLPNLDLINSVNHVAGGQMGMGVAI-QEMWK 271
           L G +  D +    + Q  V+I  +G+NGQ  NLD+ N +  +A  +    VAI   + +
Sbjct: 244 LIGGVVYDLSGMAVKGQHIVNIQTNGLNGQQVNLDVFNGITKIADSKHHSRVAIFGTLHR 303

Query: 272 HSNSY--HDRLQTMLRGMLKQGLGLASGPHSSFIPYHVDAVTLQPFGEGWQDEMAIGRVI 329
           HSN Y  +      +R +  Q      G HS    Y V  +T+    +    E   G+ I
Sbjct: 304 HSNPYMEYSPFIVPMRALYTQAFISIEGIHSVLGKYGVQGLTVGLSHD--YSEKQTGQFI 361

Query: 330 EGTFRSLNNLLEHLHQSFFFYLLMQRERFVSIGTYLPSAMLVAANFTIMAIALWVK 385
           E   R LNN+LE LHQS+F Y+L     F SI  Y+    ++ +   I A   W K
Sbjct: 362 EEVSRMLNNVLERLHQSYFMYVLADDLHFSSIAMYIIPLTILVSPLVISAYFEWTK 417
>ref|NP_916949.1| putative GPAA1 - like protein [Oryza sativa (japonica
           cultivar-group)]
 dbj|BAC01259.1| putative GPAA1 - like protein [Oryza sativa (japonica
           cultivar-group)]
          Length = 718

 Score =  366 bits (932), Expect = e-100
 Identities = 129/479 (26%), Positives = 197/479 (40%), Gaps = 107/479 (22%)

Query: 2   PRLLASALSLRRDPRLLKLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQVH 61
           PRL+     +R    L       S +C   G++ L  LP    ++ TY+SENAL+PG  +
Sbjct: 13  PRLI-----VRLGVFLASHHILFSAVCCTAGIIALLFLP--SLAKNTYLSENALIPGSAN 65

Query: 62  TYFGGSDQNVFRAYKHETDELAGK---GNIEVNDKLESIAKGLGLKVGRQNFT------- 111
           T F   D      +    +   G+   G  E+   +    K LG +V    F        
Sbjct: 66  TLFSTEDVQEANRFAKGIEAAIGESRGGTTEIPKFIAQQTKNLGAEVYYHEFLPDSKCFH 125

Query: 112 ----YSSAGN----------THSGQNIYAILQAPRGDATEAIVLVAAWKNVKGELNR-SG 156
               ++S  N          T+ G N   I++APRGD  EAIVLV  + + K   N    
Sbjct: 126 PLKFFTSMTNNMAAKPNGTYTNFGINTVGIIRAPRGDGKEAIVLVTPYNSQKVTPNELLS 185

Query: 157 VPLVLTLARYFKRWSLWSKDIIFLFTPDSIAG----PQAWVDAYHDAHDSSRVASLPL-- 210
           + L  ++     R +  SKDI++L + DS  G      +W++ YH+    S   +L    
Sbjct: 186 LALGFSVFSLLSRAAWLSKDIVWL-SADSQFGEYSAVSSWLNQYHNPMFLSHPVNLDTKI 244

Query: 211 -----------------------KSGALQGAIALDYTRETRF---QSVHIVYDGVNGQLP 244
                                  ++G +  A+        ++    SV +  +  NGQ+P
Sbjct: 245 YGANQILYKPDGTAEKAELMAFKRAGTMAAALIFKVGETRKYGDRDSVTMYAEASNGQMP 304

Query: 245 NLDLINSVNHVAGGQMGMGVAIQE-----------------------------MWK---H 272
           NLDL+N V+++A  + G  V ++                               WK    
Sbjct: 305 NLDLLNVVHYLAVHRQGFRVNVETFNSLLSSSWLRVIAEVFQNLGSLLRKINPDWKLDVT 364

Query: 273 SNSYHDRLQTMLRGMLKQGLGLASGPHSSFIPYHVDAVTLQPFGEGWQ--DEMAI----- 325
              Y +    +   M  Q LG+ +G H +F  Y VDAV+L+ F   +   +E A      
Sbjct: 365 VPDYVEGTANLASSMYNQALGVPTGSHGAFRDYQVDAVSLE-FAPAFHLKNENAKSSFLL 423

Query: 326 --GRVIEGTFRSLNNLLEHLHQSFFFYLLMQRERFVSIGTYLPSAMLVAANFTIMAIAL 382
             GR+ EG  RS+NNLLE  HQSFF Y L    +F+S+G Y+    L+ A   I+A AL
Sbjct: 424 RGGRLTEGVVRSVNNLLEKFHQSFFLYFLTAPSKFISVGVYMIPFALLLAPLPIVAAAL 482
>gb|AAO00773.1| GPAA1 - like protein [Arabidopsis thaliana]
          Length = 699

 Score =  241 bits (611), Expect = 3e-62
 Identities = 81/293 (27%), Positives = 125/293 (42%), Gaps = 44/293 (15%)

Query: 16  RLLKLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQVHTYFGGSD----QNV 71
            L+   P  S++        L LL L   ++ TYISENAL+PG   +     D      +
Sbjct: 32  FLIAHSPVFSVV--FSAAGVLALLLLPLLAKNTYISENALMPGSARSMLSNRDVSDGSKL 89

Query: 72  FRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNF-----------------TYSS 114
            +  K+      G+G +EV   +      +G +V  Q F                 +Y+ 
Sbjct: 90  VKDIKNFRLNHEGQG-VEVQKLIGKYMSDMGAEVSYQKFHPEGNQFHPLHFFSGPDSYTL 148

Query: 115 AGNTHS---GQNIYAILQAPRGDATEAIVLVAAWKNVK-GELNRSGVPLVLTLARYFKRW 170
             N      G N+  I++APRGD  E+IVLV  +  +  G+     + +V +L     R 
Sbjct: 149 LENVSCASYGVNVAGIIRAPRGDGKESIVLVTPYDFINGGDYEDLSLGIVSSLFSLLSRV 208

Query: 171 SLWSKDIIFLFTPDSIAG----PQAWVDAYHDAH---------DSSRVASLPLKSGALQG 217
           +  SKDII+L   DS  G      AW+  YH            D    A    ++G +  
Sbjct: 209 TWLSKDIIWLV-ADSRYGDYRPVAAWLTEYHSPSFKVSDLLKCDEQNTADNFRRAGTMAA 267

Query: 218 AIALDYT--RETRFQSVHIVYDGVNGQLPNLDLINSVNHVAGGQMGMGVAIQE 268
           A+ L      E    ++ I  +  NGQ+PNLDLIN VN++A  + G  V +++
Sbjct: 268 ALVLKVDGRSEKFEDTLSIYAEASNGQMPNLDLINVVNYLAVHRQGFYVKVEK 320
 Score =  155 bits (389), Expect = 3e-36
 Identities = 47/138 (34%), Positives = 75/138 (54%), Gaps = 13/138 (9%)

Query: 275 SYHDRLQTMLRGMLKQGLGLASGPHSSFIPYHVDAVTLQ------PFGEGWQDEMAI--G 326
            Y +   T+   +  Q LG+ +GPH +F  Y VDA+TL+      P  +  Q +  +   
Sbjct: 359 DYLEGSATLASSLYSQALGIPTGPHGAFRDYQVDAITLKVSPRFPPDSKTRQHDFFLRGA 418

Query: 327 RVIEGTFRSLNNLLEHLHQSFFFYLLMQRERFVSIGTYLPSAMLVAANFTIMAIALWVKS 386
           R++EGT RS+NNLLE  HQSFF Y+L    +F+S+G Y+ +  L+ A   ++A +L++  
Sbjct: 419 RLLEGTIRSVNNLLEKFHQSFFLYMLTSPSKFISVGVYMIAFALLVAPLPMVAASLYI-- 476

Query: 387 GQPDVQEIITEKTKTAEE 404
              D  + +T  T    E
Sbjct: 477 ---DGCKSLTNSTHNPTE 491
>ref|NP_197414.2| GPAA1 - like protein [Arabidopsis thaliana]
          Length = 699

 Score =  241 bits (611), Expect = 3e-62
 Identities = 81/293 (27%), Positives = 125/293 (42%), Gaps = 44/293 (15%)

Query: 16  RLLKLPPYLSLLCIVIGVVWLFLLPLDDYSRRTYISENALLPGQVHTYFGGSD----QNV 71
            L+   P  S++        L LL L   ++ TYISENAL+PG   +     D      +
Sbjct: 32  FLIAHSPVFSVV--FSAAGVLALLLLPLLAKNTYISENALMPGSARSMLSNRDVSDGSKL 89

Query: 72  FRAYKHETDELAGKGNIEVNDKLESIAKGLGLKVGRQNF-----------------TYSS 114
            +  K+      G+G +EV   +      +G +V  Q F                 +Y+ 
Sbjct: 90  VKDIKNFRLNHEGQG-VEVQKLIGKYMSDMGAEVSYQKFHPEGNQFHPLHFFSGPDSYTL 148

Query: 115 AGNTHS---GQNIYAILQAPRGDATEAIVLVAAWKNVK-GELNRSGVPLVLTLARYFKRW 170
             N      G N+  I++APRGD  E+IVLV  +  +  G+     + +V +L     R 
Sbjct: 149 LENVSCASYGVNVAGIIRAPRGDGKESIVLVTPYDFINGGDYEDLSLGIVSSLFSLLSRV 208

Query: 171 SLWSKDIIFLFTPDSIAG----PQAWVDAYHDAH---------DSSRVASLPLKSGALQG 217
           +  SKDII+L   DS  G      AW+  YH            D    A    ++G +  
Sbjct: 209 TWLSKDIIWLV-ADSRYGDYRPVAAWLTEYHSPSFKVSDLLKCDEQNTADNFRRAGTMAA 267

Query: 218 AIALDYT--RETRFQSVHIVYDGVNGQLPNLDLINSVNHVAGGQMGMGVAIQE 268
           A+ L      E    ++ I  +  NGQ+PNLDLIN VN++A  + G  V +++
Sbjct: 268 ALVLKVDGRSEKFEDTLSIYAEASNGQMPNLDLINVVNYLAVHRQGFYVKVEK 320
 Score =  155 bits (389), Expect = 3e-36
 Identities = 47/138 (34%), Positives = 75/138 (54%), Gaps = 13/138 (9%)

Query: 275 SYHDRLQTMLRGMLKQGLGLASGPHSSFIPYHVDAVTLQ------PFGEGWQDEMAI--G 326
            Y +   T+   +  Q LG+ +GPH +F  Y VDA+TL+      P  +  Q +  +   
Sbjct: 359 DYLEGSATLASSLYSQALGIPTGPHGAFRDYQVDAITLKVSPRFPPDSKTRQHDFFLRGA 418

Query: 327 RVIEGTFRSLNNLLEHLHQSFFFYLLMQRERFVSIGTYLPSAMLVAANFTIMAIALWVKS 386
           R++EGT RS+NNLLE  HQSFF Y+L    +F+S+G Y+ +  L+ A   ++A +L++  
Sbjct: 419 RLLEGTIRSVNNLLEKFHQSFFLYMLTSPSKFISVGVYMIAFALLVAPLPMVAASLYI-- 476

Query: 387 GQPDVQEIITEKTKTAEE 404
              D  + +T  T    E
Sbjct: 477 ---DGCKSLTNSTHNPTE 491
>gb|EAA16082.1| hypothetical protein [Plasmodium yoelii yoelii]
          Length = 489

 Score =  231 bits (584), Expect = 4e-59
 Identities = 57/255 (22%), Positives = 104/255 (40%), Gaps = 41/255 (16%)

Query: 137 EAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSKDIIFLFTPDSI---AGPQAWV 193
           E +++V  +   + +     + + LTL  YF   +  SKDIIFLFT   +    G + ++
Sbjct: 133 ENLIVVINFDYKERKY-FHSLVVGLTLINYFLNANYMSKDIIFLFTNKELLYSLGVKNFI 191

Query: 194 DAYHDAHDSSRVASLPLKSGALQGAIALDYTRETRFQS-VHIVYDGVNGQLPNLDLI--- 249
           + Y+  +  +R           + +I +++  E+ + S + I Y+ +NG LPN DLI   
Sbjct: 192 EHYYYGNTENRKV-------LTRSSIIIEF--ESIYPSNIEINYESLNGMLPNQDLILLL 242

Query: 250 -NSVNHVAGGQMGMGVAIQEMWKHSNSYHDRLQTMLRGMLKQGLGLASGPHSSFIP---- 304
            N +NH     + M        K    YH  L   L    ++G       H  F+     
Sbjct: 243 RNELNHY---NIPM--------KTDPVYHAILNVALEKKYEKG-------HIYFLRENIP 284

Query: 305 -YHVDAVTLQPFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQSFFFYLLMQRERFVSIGT 363
            + +  V+  P      +     + ++   RS +N  E    S  FY     +++V I  
Sbjct: 285 SFTITGVSKVPLKRKMINLFNFTKSLQSFLRSQSNTHEGFCHSTNFYFFNTIKKYVPISL 344

Query: 364 YLPSAMLVAANFTIM 378
           Y+    L+ +   + 
Sbjct: 345 YVFCVYLICSYCILK 359
>ref|NP_705572.1| hypothetical protein [Plasmodium falciparum 3D7]
 emb|CAD52809.1| hypothetical protein [Plasmodium falciparum 3D7]
          Length = 810

 Score =  230 bits (581), Expect = 9e-59
 Identities = 52/266 (19%), Positives = 101/266 (37%), Gaps = 47/266 (17%)

Query: 137 EAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSKDIIFLFTPDSI---AGPQAWV 193
           E++V+V  +   + +     V + LTL  +F + +  SKD+ FLFT   +    G Q ++
Sbjct: 134 ESLVVVINFDFKERKY-FHSVIIGLTLMEHFSKCNYMSKDVTFLFTNKELLYSLGVQEFI 192

Query: 194 DAYHDAHDSSRVASLPLKSGALQGAIALDYTRETRFQS-VHIVYDGVNGQLPNLDLINSV 252
             Y   ++++R+    ++S  +     +++  ++ + S + I Y+G+NG LPN DLI  +
Sbjct: 193 QKYFY-NNTNRIGKKIIRSSTI-----IEF--DSIYPSYIKINYEGLNGMLPNQDLILLL 244

Query: 253 NHVAGGQMGMGVAIQEMWKHSNSYHDRLQTMLRGMLKQGLGLASGPHSSFIPY------- 305
            +    ++       +M      +       L    + G       H  F+ Y       
Sbjct: 245 TN----ELHFYSIPIKMELT---HGSIFDMALEKNYENG-------HIYFLRYKKKYEYI 290

Query: 306 -------------HVDAVTLQPFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQSFFFYLL 352
                             +  P      +   + + ++   RS +N  E    S  FY  
Sbjct: 291 RDDNDEIKNIPAFTATGGSKVPIRNKMINLFNLTKALQSYLRSQSNTHEGFCHSSNFYFF 350

Query: 353 MQRERFVSIGTYLPSAMLVAANFTIM 378
               R + I  Y  S  L+ A   + 
Sbjct: 351 NTFRRHIPISIYCYSVYLICAYSIMK 376
>emb|CAB86709.1| hypothetical protein L3640.14 [Leishmania major]
          Length = 464

 Score =  214 bits (541), Expect = 4e-54
 Identities = 47/270 (17%), Positives = 85/270 (31%), Gaps = 47/270 (17%)

Query: 129 QAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSKDIIFLFTPDSIAG 188
           +  R   +E   + A +  V  +   + V L   L    +R    + D+ F F   S   
Sbjct: 75  RGRRSPGSE---IAAVY--VNTDY-PASVSLANALIEVIRRRKSLACDVQFYFVNSS--- 125

Query: 189 PQAWVDAYHDAHDSSRVASLPLKSGALQGAIALDYTRETRFQSVHIVYDGVNGQLPNLDL 248
            + W                P+     + A+ L+ +       + I   G NG  PN D 
Sbjct: 126 -EEW----------------PVPQAYTRAALVLNLSTLYNR-HICIDTLGGNGIQPNQDY 167

Query: 249 INSVNHVAGGQMGMGVA-IQEMWKHSNSYHDRLQTMLRGMLKQGLGLASGPHSSFIPYHV 307
            N    +A     +     Q   + ++  H          L+  + L + P     P+H+
Sbjct: 168 TNIAVQLAAANQFLPSYLCQRRHRSTDDAHAGFWHYW-AYLEASVQLPTRPQ----PWHI 222

Query: 308 DAV----TLQPFGEGWQDEM----------AIGRVIEGTFRSLNNLLEHLHQSFFFYLLM 353
                  T+    +                A  +++     SLN L E  H S F +L +
Sbjct: 223 IPTHSINTIAISSDPLYSASSVFPHSQLPDAFAQLVLKIIVSLNGLEEKFHHSTFVWLPV 282

Query: 354 QRERFVSIGTYLPSAMLVAANFTIMAIALW 383
              R+V         +L  A+      + +
Sbjct: 283 SLWRYVEYDHAQFCIILFVASIFSTTYSEY 312
>dbj|BAC81736.1| GPI transamidase component GAA1 [Trypanosoma brucei brucei]
          Length = 461

 Score =  192 bits (484), Expect = 2e-47
 Identities = 45/266 (16%), Positives = 86/266 (31%), Gaps = 38/266 (14%)

Query: 127 ILQAPRGDATEAIVLVAAWKNVKGELNRSGVPLVLTLARYFKRWSLWSKDIIFLFTPDSI 186
           +++  R   +E+I +               V L   L    +     + D  F F     
Sbjct: 74  VVRGRRSVGSESIAVYVNAAFEP------SVVLANHLIYVLREKENMACDTNFYF----- 122

Query: 187 AGPQAWVDAYHDAHDSSRVASLPLKSGALQGAIALDYTRETRFQSVHIVYDGVNGQLPNL 246
                        +D+S+    P+    ++ AI ++ T      ++     G NG  PN 
Sbjct: 123 ------------FNDTSK--DWPIPDSFVRAAIVINVTS-FHTNNLCFNVFGANGMQPNQ 167

Query: 247 DLINSVNHVAGG-QMGMGVAIQE---MWKHSNS----YHDRLQTMLRGMLK-QGLGLASG 297
           DL N    +A   +  + V  Q     +  S      Y   LQT L   L+ Q       
Sbjct: 168 DLFNLAVAIAEKWRFNIDVLCQNPYISFSTSRPIYEHYFLALQTALVAPLRYQPWYKMRS 227

Query: 298 PHSSFIPYHVDAVTLQPFGEGWQDEMAIGRVIEGTFRSLNNLLEHLHQSFFFYLLMQRER 357
              S +    +    +       +  A     E    +L+ L E  H S   ++ +  ++
Sbjct: 228 RGISLLAISTEKSERRTKSSYGYNMAA---AHEQLIATLSYLHERFHHSTSVWIPLSVDQ 284

Query: 358 FVSIGTYLPSAMLVAANFTIMAIALW 383
           +V       + +L  A+      +++
Sbjct: 285 YVEYDVIQFATILFVASLLSTCYSIY 310
>ref|XP_290985.3| similar to LIM and senescent cell antigen-like domains 1 [Homo
           sapiens]
          Length = 883

 Score =  179 bits (452), Expect = 1e-43
 Identities = 51/161 (31%), Positives = 73/161 (44%), Gaps = 18/161 (11%)

Query: 262 MGVAIQEMWKHSNSYHDRLQTMLRGMLKQGLGLASGPHSSFIPYHVDAVTLQ---PFGEG 318
            G    + W   +     LQT+L  +L Q           F+ YHV+A+TL+    F + 
Sbjct: 602 QGKLQPQDWTLLDELLQGLQTLLLMILWQAS------RGLFLHYHVEALTLRRISSFRQY 655

Query: 319 WQDEMAIGRVIEGTFRSLNNLLEHLHQSFFFYLLMQRERFVSIGTYLPSAMLVAANFTIM 378
             D +A G+ +EG F  LN+LLEH HQ FF YLL    RFVSIG Y+P+   +       
Sbjct: 656 KYDLVAAGKALEGMFCKLNHLLEHPHQLFFLYLLPTLSRFVSIGLYMPATSFLLLVLGFK 715

Query: 379 AIALWVKSGQPDVQEIITEKTKTAEEAERIVSPNPHVASER 419
           A+ LW++           E     EE   +  P+  +   R
Sbjct: 716 ALQLWMQL---------HEAGVGLEELRGVPDPSVPLPQHR 747
CPU time:   203.01 user secs.	    3.61 sys. secs	  206.62 total secs.

  Database: nr
    Posted date:  Nov 22, 2003  1:30 PM
  Number of letters in database: 504,497,942
  Number of sequences in database:  1,543,518
  
Lambda     K      H
   0.312    0.175    0.494 

Gapped
Lambda     K      H
   0.270   0.0615    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 580125732
Number of Sequences: 1543518
Number of extensions: 30699994
Number of successful extensions: 76780
Number of sequences better than 10.0: 43
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 76585
Number of HSP's gapped (non-prelim): 55
length of query: 454
length of database: 504,497,942
effective HSP length: 58
effective length of query: 396
effective length of database: 414,973,898
effective search space: 164329663608
effective search space used: 164329663608
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.0 bits)
S2: 77 (34.0 bits)