Sequences with E-value BETTER than threshold (0.002) 901 0.0
578 e-164
575 e-163
558 e-157
553 e-156
551 e-155
530 e-149
497 e-139
463 e-129
458 e-127
303 5e-81
89 2e-16
Alignments
>ref|NP_013189.1| (NC_001144) ER protein essential for attaching GPI
(glycosylphosphatidylinositol) to protein; Gaa1p
[Saccharomyces cerevisiae]
sp|P39012|GAA1_YEAST GAA1 PROTEIN
pir||S45053 membrane protein END2 - yeast (Saccharomyces cerevisiae)
emb|CAA55944.1| (X79409) Gaa1 [Saccharomyces cerevisiae]
gb|AAB67592.1| (U53880) Gaa1p [Saccharomyces cerevisiae]
emb|CAA97649.1| (Z73260) ORF YLR088w [Saccharomyces cerevisiae]
Length = 614
Score = 901 bits (2304), Expect = 0.0
Identities = 614/614 (100%), Positives = 614/614 (100%)
Query: 1 MALLEKLHRRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMP 60
MALLEKLHRRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMP
Sbjct: 1 MALLEKLHRRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMP 60
Query: 61 SQAYSYFRESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTKTAIYENEQYGETL 120
SQAYSYFRESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTKTAIYENEQYGETL
Sbjct: 61 SQAYSYFRESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTKTAIYENEQYGETL 120
Query: 121 YGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLARFFSRWPVWSKNIIVVFSEN 180
YGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLARFFSRWPVWSKNIIVVFSEN
Sbjct: 121 YGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLARFFSRWPVWSKNIIVVFSEN 180
Query: 181 PRAALRSWVEAYHTSLDLTGGSIEAAVVLDYSSTEDFFEYVEISYDGLNGELPNLDLVNI 240
PRAALRSWVEAYHTSLDLTGGSIEAAVVLDYSSTEDFFEYVEISYDGLNGELPNLDLVNI
Sbjct: 181 PRAALRSWVEAYHTSLDLTGGSIEAAVVLDYSSTEDFFEYVEISYDGLNGELPNLDLVNI 240
Query: 241 AISITEHEGMKVSLHGLPSDQLTNNNFWSRLKILCLGIRDWALSGVKKPHGNEAFSGWRI 300
AISITEHEGMKVSLHGLPSDQLTNNNFWSRLKILCLGIRDWALSGVKKPHGNEAFSGWRI
Sbjct: 241 AISITEHEGMKVSLHGLPSDQLTNNNFWSRLKILCLGIRDWALSGVKKPHGNEAFSGWRI 300
Query: 301 QSVTLKAHGNSGHDITTFGRIPEAMFRSINNLLEKFHQSFFFYLLLAPRQFVSISSYLPS 360
QSVTLKAHGNSGHDITTFGRIPEAMFRSINNLLEKFHQSFFFYLLLAPRQFVSISSYLPS
Sbjct: 301 QSVTLKAHGNSGHDITTFGRIPEAMFRSINNLLEKFHQSFFFYLLLAPRQFVSISSYLPS 360
Query: 361 AVALSIAFAISSLNAFINNAYANISLFSEYNLVALLVWFVSLVISFVVSQAFLLIPSSGL 420
AVALSIAFAISSLNAFINNAYANISLFSEYNLVALLVWFVSLVISFVVSQAFLLIPSSGL
Sbjct: 361 AVALSIAFAISSLNAFINNAYANISLFSEYNLVALLVWFVSLVISFVVSQAFLLIPSSGL 420
Query: 421 LMTISMASCFLPLILSRKIHISEPLSYRLKNVAFLYFSLVSTSLLMINFAMALLIGTLAF 480
LMTISMASCFLPLILSRKIHISEPLSYRLKNVAFLYFSLVSTSLLMINFAMALLIGTLAF
Sbjct: 421 LMTISMASCFLPLILSRKIHISEPLSYRLKNVAFLYFSLVSTSLLMINFAMALLIGTLAF 480
Query: 481 PMTFVKTIVESSSEHEVTTQSSNPIKTEPKDEIELVENHMDTTPATPQQQKQKLKNLVLL 540
PMTFVKTIVESSSEHEVTTQSSNPIKTEPKDEIELVENHMDTTPATPQQQKQKLKNLVLL
Sbjct: 481 PMTFVKTIVESSSEHEVTTQSSNPIKTEPKDEIELVENHMDTTPATPQQQKQKLKNLVLL 540
Query: 541 ILTNPFISITLFGLFFDDEFHGFDIINKLVSAWLDLKCWSWFVLCIGWLPCWLLILASSF 600
ILTNPFISITLFGLFFDDEFHGFDIINKLVSAWLDLKCWSWFVLCIGWLPCWLLILASSF
Sbjct: 541 ILTNPFISITLFGLFFDDEFHGFDIINKLVSAWLDLKCWSWFVLCIGWLPCWLLILASSF 600
Query: 601 ESKSVVVRSKEKQS 614
ESKSVVVRSKEKQS
Sbjct: 601 ESKSVVVRSKEKQS 614
>ref|NP_034461.1| (NM_010331) GPI anchor attachment protein 1 [Mus musculus]
dbj|BAA82589.1| (AB002136) glycosylphosphatidylinositol anchor attachment 1 (GPAA1)
[Mus musculus]
dbj|BAA82591.1| (AB002138) glycosylphosphatidylinositol anchor attachment 1 (GPAA1)
[Mus musculus]
dbj|BAB03274.1| (AB006970) GPI anchor attachment protein [Mus musculus]
dbj|BAB03275.1| (AB006971) GPI anchor attachment protein [Mus musculus]
gb|AAH06697.1|AAH06697 (BC006697) GPI anchor attachment protein 1 [Mus musculus]
Length = 621
Score = 578 bits (1476), Expect = e-164
Identities = 147/539 (27%), Positives = 244/539 (44%), Gaps = 67/539 (12%)
Query: 1 MALLEKLHRRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMP 60
M LL RR +V R+ L V+S + + F+++A P+ +RTY+SENA+
Sbjct: 1 MGLLSDPVRRRALARIVLRLNTPLCVLSYVAGIAWFLALAFPPLT---QRTYMSENAMGS 57
Query: 61 SQAYSYF--RESEWNILRGYRSQIK-----EMVNMTSMERNNLMGSWLQEFGTKTAIYE- 112
+ F + + R + + K + + R+ + + Q F K +
Sbjct: 58 TMVEEQFVGGDRARSFARDFAAHRKKPGALPVAWLERSMRSVGLEVYTQSFSRKLPFPDE 117
Query: 113 -NEQY---GETLYGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLARFFSRWPV 168
+E+Y G +YG++ APR TE++VL VP D N L ++LA F
Sbjct: 118 THERYMVSGTNVYGILRAPRSASTESLVLTVPC--GPDATNSQAVGLLLALAAHFRGQIY 175
Query: 169 WSKNIIVVFSENPRAALRSWVEAYH---------TSLDLTGGSIEAAVVLDYSSTEDFFE 219
W+K+II + +++ +W+EAYH + L G+I+AAV L+ SS D
Sbjct: 176 WAKDIIFLVTDHDLLGTEAWLEAYHDINVTGIQSSPLQGRAGAIQAAVALELSS--DVVT 233
Query: 220 YVEISYDGLNGELPNLDLVNIAISITEHEGMKVSLHG--LPSDQLTNNNFWSRLKILCLG 277
++++ +GLNG+LPNLDL+N+ + + G+ +L G P D + L+ L L
Sbjct: 234 SLDVTVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPQDWTSLEGPLQGLQTLLLM 293
Query: 278 IRDWALSGVKKPHGNEAFSGWRIQSVTLK---AHGNSGHDITTFGRIPEAMFRSINNLLE 334
+ A PHG F + ++++TL+ + +D+ T G+ E MFR +N+LLE
Sbjct: 294 VLRQASGRPHGPHG--LFLRYGVEALTLRGINSFRQYKYDLATVGKALEGMFRKLNHLLE 351
Query: 335 KFHQSFFFYLLLAPRQFVSISSYLPSAVALSIAFAISSLNAFINNAYANIS--------- 385
+ HQSFFFYLL A +FVSI Y+P+ L + + +L ++ A ++
Sbjct: 352 RLHQSFFFYLLPALSRFVSIGLYMPATGFLLLVLGLKALELWMQLHQAGVNPEEAGKAPS 411
Query: 386 ---LFSEYNLVALLVWFVSLVISFVVSQAFLLIPSSG------------------LLMTI 424
V L L+IS + A +P G L+ I
Sbjct: 412 PGTPLLPTQGVGLASLTAPLLISQAMGLALYFLPVLGQHLATQHFPVAEAEAVVLTLLAI 471
Query: 425 SMASCFLPLILSRKIHISEPLS--YRLKNVAFLYFSLVSTSLLMINFAMALLIGTLAFP 481
+A LP R ++ P LK VA +Y +L + ++NF++ L+ P
Sbjct: 472 YVAGLALPHNTHRVVNSQVPDRGWMALKLVALIYLALQLGCIALLNFSLGFLLAATMVP 530
>ref|NP_003792.1| (NM_003801) anchor attachment protein 1; anchor attachment protein
1 (Gaa1p, yeast) homolog; glycophosphatidylinositol
anchor attachment 1 [Homo sapiens]
dbj|BAA24035.1| (AB006969) hGAA1 [Homo sapiens]
dbj|BAA82588.1| (AB002135) glycosylphosphatidylinositol anchor attachment 1 (GPAA1)
[Homo sapiens]
dbj|BAA82590.1| (AB002137) glycosylphosphatidylinositol anchor attachment 1 (GPAA1)
[Homo sapiens]
gb|AAH03171.1|AAH03171 (BC003171) anchor attachment protein 1 (Gaa1p, yeast) homolog [Homo
sapiens]
gb|AAH04129.1|AAH04129 (BC004129) anchor attachment protein 1 (Gaa1p, yeast) homolog [Homo
sapiens]
Length = 621
Score = 575 bits (1468), Expect = e-163
Identities = 146/539 (27%), Positives = 238/539 (44%), Gaps = 67/539 (12%)
Query: 1 MALLEKLHRRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMP 60
M LL RR LV R+ A L V+S + + F+++ P+ +RTY+SENA+
Sbjct: 1 MGLLSDPVRRRALARLVLRLNAPLCVLSYVAGIAWFLALVFPPLT---QRTYMSENAMGS 57
Query: 61 SQAYSYFRESEWNILRGY-------RSQIKEMVNMTSMERNNLMGSWLQEFGTKTAIYE- 112
+ F + +S + + R+ + + Q F K +
Sbjct: 58 TMVEEQFAGGDRARAFARDFAAHRKKSGALPVAWLERTMRSVGLEVYTQSFSRKLPFPDE 117
Query: 113 -NEQY---GETLYGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLARFFSRWPV 168
+E+Y G +YG++ APR TE++VL VP D N L ++LA F
Sbjct: 118 THERYMVSGTNVYGILRAPRAASTESLVLTVPC--GSDSTNSQAVGLLLALAAHFRGQIY 175
Query: 169 WSKNIIVVFSENPRAALRSWVEAYH---------TSLDLTGGSIEAAVVLDYSSTEDFFE 219
W+K+I+ + +E+ +W+EAYH + L G+I+AAV L+ SS D
Sbjct: 176 WAKDIVFLVTEHDLLGTEAWLEAYHDVNVTGMQSSPLQGRAGAIQAAVALELSS--DVVT 233
Query: 220 YVEISYDGLNGELPNLDLVNIAISITEHEGMKVSLHG--LPSDQLTNNNFWSRLKILCLG 277
++++ +GLNG+LPNLDL+N+ + + G+ +L G P D + + L+ L L
Sbjct: 234 SLDVAVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPEDWTSLDGPLQGLQTLLLM 293
Query: 278 IRDWALSGVKKPHGNEAFSGWRIQSVTLK---AHGNSGHDITTFGRIPEAMFRSINNLLE 334
+ A HG F +R++++TL+ + +D+ G+ E MFR +N+LLE
Sbjct: 294 VLRQASGRPHGSHG--LFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLE 351
Query: 335 KFHQSFFFYLLLAPRQFVSISSYLPSAVALSIAFAISSLNAFINNAYANISL-------- 386
+ HQSFF YLL +FVSI Y+P+ L + + +L ++ A + L
Sbjct: 352 RLHQSFFLYLLPGLSRFVSIGLYMPAVGFLLLVLGLKALELWMQLHEAGMGLEEPGGAPG 411
Query: 387 ----FSEYNLVALLVWFVSLVISFVVSQAFLLIPSSG------------------LLMTI 424
V L L+IS + A ++P G L+ I
Sbjct: 412 PSVPLPPSQGVGLASLVAPLLISQAMGLALYVLPVLGQHVATQHFPVAEAEAVVLTLLAI 471
Query: 425 SMASCFLPLILSRKIHISEPLS--YRLKNVAFLYFSLVSTSLLMINFAMALLIGTLAFP 481
A LP R + P LK VA +Y +L + + NF++ L+ T P
Sbjct: 472 YAAGLALPHNTHRVVSTQAPDRGWMALKLVALIYLALQLGCIALTNFSLGFLLATTMVP 530
>ref|NP_491700.1| (NM_059299) F33D11.9b.p [Caenorhabditis elegans]
gb|AAK68360.1|AF039720_13 (AF039720) Hypothetical protein F33D11.9b [Caenorhabditis elegans]
Length = 670
Score = 558 bits (1424), Expect = e-157
Identities = 115/537 (21%), Positives = 214/537 (39%), Gaps = 78/537 (14%)
Query: 9 RRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMPSQAYSYFR 68
R + ++ L +I+ + A + T ISE++LMP F
Sbjct: 29 RPKILDKILKFRKVAL-IIAYIGAYLSAQWLFDPVNMEV---TRISEHSLMPGLVTPKFD 84
Query: 69 ESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTK-------TAIYENEQYGETLY 121
+S I + YR + ++ S + L+ + + G + + + N GE +Y
Sbjct: 85 KSGIAI-QLYR-RFSDLPK--SKSQQELIHTIFSDLGLECFTHKWRSKVAGNPMNGENVY 140
Query: 122 GVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLARFFSRWPVWSKNIIVVFS--- 178
G + PR DG EA ++ V S+ + L + + W+++I++VF
Sbjct: 141 GFIRGPRNDGAEAQMIVVQLGRSEKSRRMMSRML--AFVDYAKDQVYWARDIVIVFVDGG 198
Query: 179 ------ENPRAALRSWV------EAYHTSLDLT---------GGSIEAAVVLDYSSTEDF 217
E AL +++ EA ++ +T G++ VV D S
Sbjct: 199 EKNDSIEKAAFALDAFLLKYQKIEALNSKKSITVEADEIQAQTGALIGGVVYDLSGMAVK 258
Query: 218 FEY-VEISYDGLNGELPNLDLVN--IAISITEHEGMKVSLHGLPSDQLTNNNFWSRLKIL 274
++ V I +GLNG+ NLD+ N I+ ++H +V++ G +S +
Sbjct: 259 GQHIVNIQTNGLNGQQVNLDVFNGITKIADSKHHS-RVAIFGTLHRHSNPYMEYSPFIVP 317
Query: 275 CLGIRDWALSGVKKPHGNEAFSGWRIQSVTLKAHGNSGHDITTFGRIPEAMFRSINNLLE 334
+ A ++ H + +Q +T+ + T G+ E + R +NN+LE
Sbjct: 318 MRALYTQAFISIEGIH--SVLGKYGVQGLTVGLSHDYSEKQT--GQFIEEVSRMLNNVLE 373
Query: 335 KFHQSFFFYLLLAPRQFVSISSYLPSAVALSIAFAISSLNAF----------INNAYANI 384
+ HQS+F Y+L F SI+ Y+ L IS+ + ++ A+ +
Sbjct: 374 RLHQSYFMYVLADDLHFSSIAMYIIPLTILVSPLVISAYFEWTKIQEFQFPVVHLAFHVL 433
Query: 385 SLFSEYNLVALLVWFVSLVISFV---VSQAFLLI--------PSSGLLMTISMASCFLPL 433
F +A F ++ +FV + F+ I PS L+ + + F +
Sbjct: 434 GFFY---YIATTYVFQTIGTTFVLQWMQWPFVGIDGCDGQFTPSWSLINSFLI---FFMI 487
Query: 434 ILSRKIHISEPLSY--RLKNVAFLYFSLVSTSLLMINFAMALLIGTLAFPMTFVKTI 488
L + + EP+ ++ V L SLV + + NF +A+L P+ F+ T
Sbjct: 488 PLGPYVFLKEPVRCVPSMRIVCLLETSLVLYGICLTNFGLAILCTAFVVPIVFLMTT 544
>ref|NP_572273.1| (NM_132045) CG3033 gene product [Drosophila melanogaster]
gb|AAK77275.1| (AY047543) GH05723p [Drosophila melanogaster]
Length = 561
Score = 553 bits (1411), Expect = e-156
Identities = 136/572 (23%), Positives = 231/572 (39%), Gaps = 93/572 (16%)
Query: 1 MALLEKLHRRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMP 60
M LL LV + + + + G L + TY+SENAL P
Sbjct: 1 MGLLSDPSIS-TQSKLVDGLARHVRKVCYALYVAGVAWFFCLALPEFNHGTYLSENALSP 59
Query: 61 SQAYSYFR-ESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTKTAIYE------- 112
Y R ++ ++ +E + S + + + + EFG +T +
Sbjct: 60 GLVYPEIRIDANRLAIQLLEELQRERKDHLSTTPHAWIAAKMNEFGLETHTHNYTLRYPF 119
Query: 113 ---NEQYGETLYGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAA--LGVSLARFFSRWP 167
E +G+ +YG++ APR TE +V A P+ + A+ L ++ A F R
Sbjct: 120 GGGKEYHGKNIYGILRAPRIASTEGIVFAAPYRAASSVHTDISASVPLLLAFADFARRKN 179
Query: 168 VWSKNIIVVFSENPRAALRSWVEAYHT---SLDL------------TGGSIEAAVVLDYS 212
W+K++I + +E + +++W+EAYH LDL GS++AA+ ++
Sbjct: 180 YWAKDLIFLITEQEQLGMQAWLEAYHDGDRELDLSKAYLRPGNLPARAGSLQAALNIEVQ 239
Query: 213 STEDFFEYVEISYDGLNGELPNLDLVNIAISITEHEGMKVSLHGLPS------DQLTNNN 266
E ++V++ +GLNG+LPNLD+ N+ I EG+ P N
Sbjct: 240 DLE--IDHVDVRIEGLNGKLPNLDMFNLVQRIMAREGIASGYKQAPRKKRRHSQSHFEQN 297
Query: 267 FWSRLKILCLGIRDWALSGVKKPHGNEAFSGWRIQSVTLKAHG---------NSGHDITT 317
F L +L + HG F +RI ++T+ A+ + G
Sbjct: 298 FRQMLTMLAS----QSSGVPTGNHG--LFHRYRIDALTIAANRRATHATLKGSPGSAAVP 351
Query: 318 FGRIPEAMFRSINNLLEKFHQSFFFYLLLAPRQFVSISSYLPSAVALSIAFAISSLNAFI 377
+ E + RS+NNLLE+FHQSFFFY++++ +++SI Y+P+ VAL + + +
Sbjct: 352 LLKAIEGIARSLNNLLERFHQSFFFYVIVSNDRYISIGDYMPALVALVACAFLKAYLTWS 411
Query: 378 NNAYANISL------------------------FSEYNLVALLVWFVSLVISFVV----- 408
N L F L+ +L+I F+
Sbjct: 412 TLPATNAELEKAAGWLREHEQEAELEENLEPDKFELPYGSVLIYLTATLLIGFLCNVLPL 471
Query: 409 SQAFLLIP------SSGLLMTISMASCFLPLILSRKIHISEPLSYRLKNVAFLYF-SLVS 461
Q FL IP ++ +L +S+ L + + P L +VAFL
Sbjct: 472 QQYFLEIPMGAAPLTTSVLSFLSLIGFVL-----PFVVVLPPGGLELLHVAFLLIYGCAL 526
Query: 462 TSLLMINFAMALLIGTLAFPMTFVKTIVESSS 493
+ ++NFA+ L L P+ E +S
Sbjct: 527 IVIGLLNFALGLFAAVLTVPLVIALETKEENS 558
>gb|AAF46094.1| (AE003435) CG3033 gene product [Drosophila melanogaster]
Length = 674
Score = 551 bits (1406), Expect = e-155
Identities = 136/572 (23%), Positives = 231/572 (39%), Gaps = 93/572 (16%)
Query: 1 MALLEKLHRRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMP 60
M LL LV + + + + G L + TY+SENAL P
Sbjct: 1 MGLLSDPSIS-TQSKLVDGLARHVRKVCYALYVAGVAWFFCLALPEFNHGTYLSENALSP 59
Query: 61 SQAYSYFR-ESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTKTAIYE------- 112
Y R ++ ++ +E + S + + + + EFG +T +
Sbjct: 60 GLVYPEIRIDANRLAIQLLEELQRERKDHLSTTPHAWIAAKMNEFGLETHTHNYTLRYPF 119
Query: 113 ---NEQYGETLYGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAA--LGVSLARFFSRWP 167
E +G+ +YG++ APR TE +V A P+ + A+ L ++ A F R
Sbjct: 120 GGGKEYHGKNIYGILRAPRIASTEGIVFAAPYRAASSVHTDISASVPLLLAFADFARRKN 179
Query: 168 VWSKNIIVVFSENPRAALRSWVEAYHT---SLDL------------TGGSIEAAVVLDYS 212
W+K++I + +E + +++W+EAYH LDL GS++AA+ ++
Sbjct: 180 YWAKDLIFLITEQEQLGMQAWLEAYHDGDRELDLSKAYLRPGNLPARAGSLQAALNIEVQ 239
Query: 213 STEDFFEYVEISYDGLNGELPNLDLVNIAISITEHEGMKVSLHGLPS------DQLTNNN 266
E ++V++ +GLNG+LPNLD+ N+ I EG+ P N
Sbjct: 240 DLE--IDHVDVRIEGLNGKLPNLDMFNLVQRIMAREGIASGYKQAPRKKRRHSQSHFEQN 297
Query: 267 FWSRLKILCLGIRDWALSGVKKPHGNEAFSGWRIQSVTLKAHG---------NSGHDITT 317
F L +L + HG F +RI ++T+ A+ + G
Sbjct: 298 FRQMLTMLAS----QSSGVPTGNHG--LFHRYRIDALTIAANRRATHATLKGSPGSAAVP 351
Query: 318 FGRIPEAMFRSINNLLEKFHQSFFFYLLLAPRQFVSISSYLPSAVALSIAFAISSLNAFI 377
+ E + RS+NNLLE+FHQSFFFY++++ +++SI Y+P+ VAL + + +
Sbjct: 352 LLKAIEGIARSLNNLLERFHQSFFFYVIVSNDRYISIGDYMPALVALVACAFLKAYLTWS 411
Query: 378 NNAYANISL------------------------FSEYNLVALLVWFVSLVISFVV----- 408
N L F L+ +L+I F+
Sbjct: 412 TLPATNAELEKAAGWLREHEQEAELEENLEPDKFELPYGSVLIYLTATLLIGFLCNVLPL 471
Query: 409 SQAFLLIP------SSGLLMTISMASCFLPLILSRKIHISEPLSYRLKNVAFLYF-SLVS 461
Q FL IP ++ +L +S+ L + + P L +VAFL
Sbjct: 472 QQYFLEIPMGAAPLTTSVLSFLSLIGFVL-----PFVVVLPPGGLELLHVAFLLIYGCAL 526
Query: 462 TSLLMINFAMALLIGTLAFPMTFVKTIVESSS 493
+ ++NFA+ L L P+ E +S
Sbjct: 527 IVIGLLNFALGLFAAVLTVPLVIALETKEENS 558
>emb|CAB65611.1| (AL136078) putative glycosylphosphatidylinositol anchor attachment
protein [Schizosaccharomyces pombe]
Length = 581
Score = 530 bits (1353), Expect = e-149
Identities = 148/503 (29%), Positives = 249/503 (49%), Gaps = 45/503 (8%)
Query: 12 VDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMPSQAYSYFRESE 71
V + + P + L + + L G I ILP + R ++SE+AL+P Q +YF
Sbjct: 7 VQIRVFPFLQRHLFFLQLSLTLIGLSWIFILPRNEIIDRLHVSESALLPGQVNTYFENRY 66
Query: 72 WNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTKTAIYENEQ-----------YGETL 120
+ + ++ + N M L++ T + +Q G
Sbjct: 67 SKTVSSSLTAANTWSHLDASVGTNTMYDDLEQIFTAMGLPTQKQNYSINIPGSEFNGSNF 126
Query: 121 YGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLARFFSRWPVWSKNIIVVFSEN 180
+ APRGD TE+++L VPW + ++N G AL +SL ++F W +WSK+II+V ++
Sbjct: 127 ITTLRAPRGDATESLLLCVPWKDHIGQYNEAGVALAISLLKYFQGWSLWSKDIILVIFDD 186
Query: 181 PRAALRSWVEAY---------HTSLDLTGGSIEAAVVLDYSSTEDFFEYVEISYDGLNGE 231
P S++ +Y +T L + GSI+A + L+ +TE+ + +E+ Y NG+
Sbjct: 187 PVYGPSSFLTSYFDQTTPYISYTPLKIRSGSIQAGLSLELVTTENNSDVLEVLYQATNGQ 246
Query: 232 LPNLDLVN-IAISITEHEGMKVSLHGLPSDQLTNNNFWSRLKILCLGIRDWALSGVKKPH 290
LPNLDL N I+ +H + L G + +++ SRLK L +G+ A+S V H
Sbjct: 247 LPNLDLFNTISRIFMQHFNYPLRLQGYDFHANSGSSYTSRLKSLWMGMLTQAVSNVTSAH 306
Query: 291 GNEAFSGWRIQSVTL--KAHGNSGHDITTFGRIPEAMFRSINNLLEKFHQSFFFYLLLAP 348
F +RI +TL K D+ FG+ E+ FRS+NNLLE HQSFFFY +L
Sbjct: 307 A--LFPQYRIDMLTLRMKVKDPFSFDMFRFGQAIESTFRSLNNLLEHLHQSFFFYFILDH 364
Query: 349 RQFVSISSYLPSAVALSIAFAISSLNAFINNAYANISLFSEYNLVALLVWFVSLVISFVV 408
F+SI +Y+PS + L+ +F + + +IN I L+ ++ W S+ F
Sbjct: 365 LHFISIGNYMPSILILAASFMLGAYRHWIN-HEKKIDLWRPFSF-----WLFSI---FCT 415
Query: 409 SQAFLLIPSS---GLLMTISMASCFLPLILSRKIHISEP---LSYRLKNVAFLYFSLVST 462
A+ L+ SS + + + + F+ +I S + + LSY L + + L+ S+VST
Sbjct: 416 IAAYYLVSSSTKITVFIFLYLMLTFIGIIFSTFMTSEDAELVLSYDLMSKS-LFISVVST 474
Query: 463 SLLMINFAMALLIGTLAFPMTFV 485
+NF+++ ++ L P+ F+
Sbjct: 475 ----LNFSLSFVVAILLVPLQFI 493
>pir||T32771 hypothetical protein F33D11.9b - Caenorhabditis elegans
Length = 885
Score = 497 bits (1267), Expect = e-139
Identities = 101/489 (20%), Positives = 191/489 (38%), Gaps = 76/489 (15%)
Query: 9 RRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMPSQAYSYFR 68
R + ++ L +I+ + A + T ISE++LMP F
Sbjct: 291 RPKILDKILKFRKVAL-IIAYIGAYLSAQWLFDPVNMEV---TRISEHSLMPGLVTPKFD 346
Query: 69 ESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTK-------TAIYENEQYGETLY 121
+S I + YR + ++ S + L+ + + G + + + N GE +Y
Sbjct: 347 KSGIAI-QLYR-RFSDLPK--SKSQQELIHTIFSDLGLECFTHKWRSKVAGNPMNGENVY 402
Query: 122 GVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLARFFSRWPVWSKNIIVVFS--- 178
G + PR DG EA ++ V S+ + L + + W+++I++VF
Sbjct: 403 GFIRGPRNDGAEAQMIVVQLGRSEKSRRMMSRML--AFVDYAKDQVYWARDIVIVFVDGG 460
Query: 179 ------ENPRAALRSWV------EAYHTSLDLT---------GGSIEAAVVLDYSSTEDF 217
E AL +++ EA ++ +T G++ VV D S
Sbjct: 461 EKNDSIEKAAFALDAFLLKYQKIEALNSKKSITVEADEIQAQTGALIGGVVYDLSGMAVK 520
Query: 218 FEY-VEISYDGLNGELPNLDLVN--IAISITEHEGMKVSLHGLPSDQLTNNNFWSRLKIL 274
++ V I +GLNG+ NLD+ N I+ ++H +V++ G +S +
Sbjct: 521 GQHIVNIQTNGLNGQQVNLDVFNGITKIADSKHHS-RVAIFGTLHRHSNPYMEYSPFIVP 579
Query: 275 CLGIRDWALSGVKKPHGNEAFSGWRIQSVTLKAHGNSGHDITTFGRIPEAMFRSINNLLE 334
+ A ++ H + +Q +T+ + T G+ E + R +NN+LE
Sbjct: 580 MRALYTQAFISIEGIH--SVLGKYGVQGLTVGLSHDYSEKQT--GQFIEEVSRMLNNVLE 635
Query: 335 KFHQSFFFYLLLAPRQFVSISSYLPSAVALSIAFAISSLNAF----------INNAYANI 384
+ HQS+F Y+L F SI+ Y+ L IS+ + ++ A+ +
Sbjct: 636 RLHQSYFMYVLADDLHFSSIAMYIIPLTILVSPLVISAYFEWTKIQEFQFPVVHLAFHVL 695
Query: 385 SLFSEYNLVALLVWFVSLVISFV---VSQAFLLI--------PSSGLLMTISMASCFLPL 433
F +A F ++ +FV + F+ I PS L+ + + F +
Sbjct: 696 GFFY---YIATTYVFQTIGTTFVLQWMQWPFVGIDGCDGQFTPSWSLINSFLI---FFMI 749
Query: 434 ILSRKIHIS 442
L + +
Sbjct: 750 PLGPYVFLK 758
>ref|NP_197414.1| (NM_121918) GPAA1 - like protein [Arabidopsis thaliana]
Length = 696
Score = 463 bits (1181), Expect = e-129
Identities = 136/585 (23%), Positives = 232/585 (39%), Gaps = 120/585 (20%)
Query: 9 RRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMPSQAYSYFR 68
R IV +G+ +IA PV S++ + G +++ + + + TYISENALMP A S
Sbjct: 24 RPIVRLGI--FLIAHSPVFSVVFSAAGVLALLL--LPLLAKNTYISENALMPGSARSMLS 79
Query: 69 ESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTKTA------------------- 109
+ + IK + L+G ++ + G + +
Sbjct: 80 NRDVSDGSKLVKDIKNFRLNHEGQVQKLIGKYMSDMGAEVSYQKFHPEGNQFHPLHFFSG 139
Query: 110 -----IYEN---EQYGETLYGVMHAPRGDGTEAMVLAVPW-FNSDDEFNIGGAALGVSLA 160
+ EN YG + G++ APRGDG E++VL P+ F + ++ + SL
Sbjct: 140 PDSYTLLENVSCASYGVNVAGIIRAPRGDGKESIVLVTPYDFINGGDYEDLSLGIVSSLF 199
Query: 161 RFFSRWPVWSKNIIVVFSENPRAALR---SWVEAYHTS-LDL----------------TG 200
SR SK+II + +++ R +W+ YH+ +
Sbjct: 200 SLLSRVTWLSKDIIWLVADSRYGDYRPVAAWLTEYHSPSFKVSDLLKCDEQNTADNFRRA 259
Query: 201 GSIEAAVVLDYSS-TEDFFEYVEISYDGLNGELPNLDLVNIAISITEHEG---------- 249
G++ AA+VL +E F + + I + NG++PNLDL+N+ + H
Sbjct: 260 GTMAAALVLKVDGRSEKFEDTLSIYAEASNGQMPNLDLINVVNYLAVHRQGFYVKVEKVV 319
Query: 250 -MKVS----LHGLPS------------DQLTN---NNFWSRLKILCLGIRDWALSGVKKP 289
+ S + G D ++ L + AL P
Sbjct: 320 SLLSSSWLKIFGEIFEAVGKLAHMLNPDWNFGIPAADYLEGSATLASSLYSQALGIPTGP 379
Query: 290 HGNEAFSGWRIQSVTLKAHG-------NSGHDITTFG-RIPEAMFRSINNLLEKFHQSFF 341
HG AF +++ ++TLK HD G R+ E RS+NNLLEKFHQSFF
Sbjct: 380 HG--AFRDYQVDAITLKVSPRFPPDSKTRQHDFFLRGARLLEGTIRSVNNLLEKFHQSFF 437
Query: 342 FYLLLAPRQFVSISSYLPSAVALSIAFAISSLNAFI------NNAYAN----------IS 385
Y+L +P +F+S+ Y+ + L + + + +I N+ N +
Sbjct: 438 LYMLTSPSKFISVGVYMIAFALLVAPLPMVAASLYIDGCKSLTNSTHNPTENFKSWKWLD 497
Query: 386 LFSEYNLVALLVWFVSLVISFVVSQAFLLIPS-----SGLLMTISMASCFLPLI-LSRKI 439
+ + LL + V+L+ F+ P+ G + + F+ + S
Sbjct: 498 AAKQVFTLHLLGFIVTLLPYFICQVPGQHSPTNRSIMWGTTSSSLLLITFVTMPGCSPFS 557
Query: 440 HISEPLSYR-LKNV--AFLYFSLVSTSLLMINFAMALLIGTLAFP 481
++ LK+V + + L S+ INFA A + L P
Sbjct: 558 SRLHGTNWAILKSVTISAAFIGLCLMSI--INFATAEIGALLLVP 600
Score = 239 bits (606), Expect = 8e-62
Identities = 72/290 (24%), Positives = 125/290 (42%), Gaps = 53/290 (18%)
Query: 9 RRIVDMGLVPRIIALLPVISMLCALFGFISIAILPMDGQYRRTYISENALMPSQAYSYFR 68
R IV +G+ +IA PV S++ + G +++ + + + TYISENALMP A S
Sbjct: 24 RPIVRLGI--FLIAHSPVFSVVFSAAGVLALLL--LPLLAKNTYISENALMPGSARSMLS 79
Query: 69 ESEWNILRGYRSQIKEMVNMTSMERNNLMGSWLQEFGTKTA------------------- 109
+ + IK + L+G ++ + G + +
Sbjct: 80 NRDVSDGSKLVKDIKNFRLNHEGQVQKLIGKYMSDMGAEVSYQKFHPEGNQFHPLHFFSG 139
Query: 110 -----IYEN---EQYGETLYGVMHAPRGDGTEAMVLAVPW-FNSDDEFNIGGAALGVSLA 160
+ EN YG + G++ APRGDG E++VL P+ F + ++ + SL
Sbjct: 140 PDSYTLLENVSCASYGVNVAGIIRAPRGDGKESIVLVTPYDFINGGDYEDLSLGIVSSLF 199
Query: 161 RFFSRWPVWSKNIIVVFSENPRAALR---SWVEAYHTS-LDL----------------TG 200
SR SK+II + +++ R +W+ YH+ +
Sbjct: 200 SLLSRVTWLSKDIIWLVADSRYGDYRPVAAWLTEYHSPSFKVSDLLKCDEQNTADNFRRA 259
Query: 201 GSIEAAVVLDYSS-TEDFFEYVEISYDGLNGELPNLDLVNIAISITEHEG 249
G++ AA+VL +E F + + I + NG++PNLDL+N+ + H
Sbjct: 260 GTMAAALVLKVDGRSEKFEDTLSIYAEASNGQMPNLDLINVVNYLAVHRQ 309
>pir||T46923 hypothetical protein DKFZp434E1512.1 - human
emb|CAB75660.1| (AL157437) hypothetical protein [Homo sapiens]
gb|AAH06383.1|AAH06383 (BC006383) Unknown (protein for MGC:12663) [Homo sapiens]
Length = 499
Score = 458 bits (1166), Expect = e-127
Identities = 117/411 (28%), Positives = 187/411 (45%), Gaps = 52/411 (12%)
Query: 117 GETLYGVMHAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLARFFSRWPVWSKNIIVV 176
G +YG++ APR TE++VL VP D N L ++LA F W+K+I+ +
Sbjct: 4 GTNVYGILRAPRAASTESLVLTVPC--GSDSTNSQAVGLLLALAAHFRGQIYWAKDIVFL 61
Query: 177 FSENPRAALRSWVEAYH---------TSLDLTGGSIEAAVVLDYSSTEDFFEYVEISYDG 227
+E+ +W+EAYH + L G+I+AAV L+ SS D ++++ +G
Sbjct: 62 VTEHDLLGTEAWLEAYHDVNVTGMQSSPLQGRAGAIQAAVALELSS--DVVTSLDVAVEG 119
Query: 228 LNGELPNLDLVNIAISITEHEGMKVSLHG--LPSDQLTNNNFWSRLKILCLGIRDWALSG 285
LNG+LPNLDL+N+ + + G+ +L G P D + + L+ L L + A
Sbjct: 120 LNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPEDWTSLDGPLQGLQTLLLMVLRQASGR 179
Query: 286 VKKPHGNEAFSGWRIQSVTLK---AHGNSGHDITTFGRIPEAMFRSINNLLEKFHQSFFF 342
HG F +R++++TL+ + +D+ G+ E MFR +N+LLE+ HQSFF
Sbjct: 180 PHGSHG--LFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSFFL 237
Query: 343 YLLLAPRQFVSISSYLPSAVALSIAFAISSLNAFINNAYANISL------------FSEY 390
YLL +FVSI Y+P+ L + + +L ++ A + L
Sbjct: 238 YLLPGLSRFVSIGLYMPAVGFLLLVLGLKALELWMQLHEAGMGLEEPGGAPGPSVPLPPS 297
Query: 391 NLVALLVWFVSLVISFVVSQAFLLIPSSG------------------LLMTISMASCFLP 432
V L L+IS + A ++P G L+ I A LP
Sbjct: 298 QGVGLASLVAPLLISQAMGLALYVLPVLGQHVATQHFPVAEAEAVVLTLLAIYAAGLALP 357
Query: 433 LILSRKIHISEPLS--YRLKNVAFLYFSLVSTSLLMINFAMALLIGTLAFP 481
R + P LK VA +Y +L + + NF++ L+ T P
Sbjct: 358 HNTHRVVSTQAPDRGWMALKLVALIYLALQLGCIALTNFSLGFLLATTMVP 408
>emb|CAB86709.1| (AL163505) hypothetical protein L3640.14 [Leishmania major]
Length = 464
Score = 303 bits (770), Expect = 5e-81
Identities = 61/358 (17%), Positives = 130/358 (36%), Gaps = 48/358 (13%)
Query: 125 HAPRGDGTEAMVLAVPWFNSDDEFNIGGAALGVSLARFFSRWPVWSKNIIVVFSENPRAA 184
R G+E +A + N+D +L +L R + ++ F +
Sbjct: 75 RGRRSPGSE---IAAVYVNTD---YPASVSLANALIEVIRRRKSLACDVQFYFVNSS--- 125
Query: 185 LRSWVEAYHTSLDLTGGSIEAAVVLDYSSTEDFFEYVEISYDGLNGELPNLDLVNIAISI 244
E + T AA+VL+ S+ + ++ I G NG PN D NIA+ +
Sbjct: 126 -----EEWPVPQAYT----RAALVLNLSTLYNR--HICIDTLGGNGIQPNQDYTNIAVQL 174
Query: 245 TEHEGMKVSLHGLPSDQLTNNNFWSRLKILCLGIRDWALSGVKKPHGNEAFSGWRIQSVT 304
S + ++ + + ++ +P I ++
Sbjct: 175 AAANQFLPSYLCQ-RRHRSTDDAHAGFWHYW-AYLEASVQLPTRPQPWHIIPTHSINTIA 232
Query: 305 LKAHGNSGHDIT--------TFGRIPEAMFRSINNLLEKFHQSFFFYLLLAPRQFVS--- 353
+ + F ++ + S+N L EKFH S F +L ++ ++V
Sbjct: 233 ISSDPLYSASSVFPHSQLPDAFAQLVLKIIVSLNGLEEKFHHSTFVWLPVSLWRYVEYDH 292
Query: 354 ----ISSYLPSAVALSIA----FAISSLNAFINNAYANISLFSEYNLVALLVWFVSLVIS 405
I ++ S + + + IS F+ ++ + + + W+ + S
Sbjct: 293 AQFCIILFVASIFSTTYSEYQLRGISITPLFVTLLLTPVAAAAAFQVAG---WWAVVSAS 349
Query: 406 FVVSQAFLLI---PSSGLLMTISMASCFLPLILSRKIHISEPLSYRLKNVAFLYFSLV 460
S F L+ +SG+L++ + + L +IL + + ++ V+F++ +L
Sbjct: 350 AAFSLLFRLLMGHANSGMLLSFNAIALCLLIILQPACGLVAGAAAAIQ-VSFIHTALQ 406
>ref|NP_491701.1| (NM_059300) F33D11.9a.p [Caenorhabditis elegans]
pir||T32772 hypothetical protein F33D11.9a - Caenorhabditis elegans
gb|AAB96702.1| (AF039720) Hypothetical protein F33D11.9a [Caenorhabditis elegans]
Length = 229
Score = 89.1 bits (219), Expect = 2e-16
Identities = 17/108 (15%), Positives = 36/108 (32%), Gaps = 27/108 (25%)
Query: 356 SYLPSAVALSIAFAISSLNAF----------INNAYANISLFSEYNLVALLVWFVSLVIS 405
Y+ L IS+ + ++ A+ + F +A F ++ +
Sbjct: 1 MYIIPLTILVSPLVISAYFEWTKIQEFQFPVVHLAFHVLGFFY---YIATTYVFQTIGTT 57
Query: 406 FV---VSQAFLLI--------PSSGLLMTISMASCFLPLILSRKIHIS 442
FV + F+ I PS L+ + + F + L + +
Sbjct: 58 FVLQWMQWPFVGIDGCDGQFTPSWSLINSFLI---FFMIPLGPYVFLK 102
CPU time: 150.61 user secs. 2.49 sys. secs 153.10 total secs.
Database: nr
Posted date: Apr 21, 2002 2:19 PM
Number of letters in database: 277,845,442
Number of sequences in database: 887,402
Lambda K H
0.315 0.168 0.465
Gapped
Lambda K H
0.270 0.0589 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 382960852
Number of Sequences: 887402
Number of extensions: 18867665
Number of successful extensions: 62215
Number of sequences better than 10.0: 218
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 200
Number of HSP's that attempted gapping in prelim test: 62002
Number of HSP's gapped (non-prelim): 277
length of query: 614
length of database: 277,845,442
effective HSP length: 57
effective length of query: 557
effective length of database: 227,263,528
effective search space: 126585785096
effective search space used: 126585785096
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.2 bits)
S2: 76 (33.7 bits)
