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GPI Anchor Biosynthesis Report: EAA07058.1 (GAA1 family, Anopheles gambiae str. PEST)




BLASTP 2.1.1 [Aug-8-2000]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 
         (647 letters)

Database: nr
           1,315,992 sequences; 421,297,171 total letters

Searching..................................................

Converged !!!


Results of PSI-Blast iteration 2

Distribution of 21 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)

gb|EAA07058.1| agCP7251 [Anopheles gambiae str. PEST] 889 0.0
ref|NP_572273.2| CG3033-PA [Drosophila melanogaster] >gi|7290645... 791 0.0
ref|NP_034461.1| GPI anchor attachment protein 1 [Mus musculus] ... 729 0.0
ref|XP_235447.1| similar to GPI anchor attachment protein 1 [Mus... 721 0.0
ref|NP_003792.1| anchor attachment protein 1; anchor attachment ... 701 0.0
gb|AAK77275.1| GH05723p [Drosophila melanogaster] 695 0.0
ref|NP_491700.2| Putative plasma membrane membrane protein famil... 677 0.0
pir||T46923 hypothetical protein DKFZp434E1512.1 - human >gi|701... 568 e-160
ref|NP_197414.1| GPAA1 - like protein; protein id: At5g19130.1 [... 548 e-154
gb|AAO00773.1| GPAA1 - like protein [Arabidopsis thaliana] 546 e-154
pir||T32771 hypothetical protein F33D11.9b - Caenorhabditis elegans 539 e-151
dbj|BAC01259.1| putative GPAA1 - like protein [Oryza sativa (jap... 531 e-149
ref|NP_593498.1| putative glycosylphosphatidylinositol anchor at... 499 e-139
gb|EAA16082.1| hypothetical protein [Plasmodium yoelii yoelii] 262 1e-68
ref|NP_705572.1| hypothetical protein [Plasmodium falciparum 3D7... 246 1e-63
emb|CAB86709.1| hypothetical protein L3640.14 [Leishmania major] 228 2e-58
ref|NP_491701.1| Putative endoplasmic reticulum membrane protein... 115 3e-24
Sequences with E-value WORSE than threshold

gb|AAF03176.1|AF110138_8 NADH dehydrogenase subunit 4 [Nephrosel... 38 0.88
sp|P30803|CYA5_CANFA Adenylate cyclase, type V (ATP pyrophosphat... 37 2.4
Alignments
>gb|EAA07058.1| agCP7251 [Anopheles gambiae str. PEST]
          Length = 647

 Score =  889 bits (2275), Expect = 0.0
 Identities = 647/647 (100%), Positives = 647/647 (100%)

Query: 1   TRTMGLLTNPSISQKAKYCRKLVRYNTAICLTLYLLGVGFFCALPDANFNSGTYFSENAL 60
           TRTMGLLTNPSISQKAKYCRKLVRYNTAICLTLYLLGVGFFCALPDANFNSGTYFSENAL
Sbjct: 1   TRTMGLLTNPSISQKAKYCRKLVRYNTAICLTLYLLGVGFFCALPDANFNSGTYFSENAL 60

Query: 61  LPGLVNSELEMETVNLVKSLSSELQRERENYPKGMPYPWLLAKMRRFGLETHTHNFTLNY 120
           LPGLVNSELEMETVNLVKSLSSELQRERENYPKGMPYPWLLAKMRRFGLETHTHNFTLNY
Sbjct: 61  LPGLVNSELEMETVNLVKSLSSELQRERENYPKGMPYPWLLAKMRRFGLETHTHNFTLNY 120

Query: 121 PFGGGKRFKGENVYGILRAPRIASTEAIVISVPYRPPETVHTDVSAGVPLMLAFADFARR 180
           PFGGGKRFKGENVYGILRAPRIASTEAIVISVPYRPPETVHTDVSAGVPLMLAFADFARR
Sbjct: 121 PFGGGKRFKGENVYGILRAPRIASTEAIVISVPYRPPETVHTDVSAGVPLMLAFADFARR 180

Query: 181 KKYWAKDIIFLVTEQEQLGMQAWLEAYHGGDEGRILDSGLLRARAGSIQAALNLEVQSLD 240
           KKYWAKDIIFLVTEQEQLGMQAWLEAYHGGDEGRILDSGLLRARAGSIQAALNLEVQSLD
Sbjct: 181 KKYWAKDIIFLVTEQEQLGMQAWLEAYHGGDEGRILDSGLLRARAGSIQAALNLEVQSLD 240

Query: 241 ISHINLKIEGLNGQLPNLDLHNLVQKLSSKNGIIAGYKQSSSSPKRSFRYQDKLLNLLSM 300
           ISHINLKIEGLNGQLPNLDLHNLVQKLSSKNGIIAGYKQSSSSPKRSFRYQDKLLNLLSM
Sbjct: 241 ISHINLKIEGLNGQLPNLDLHNLVQKLSSKNGIIAGYKQSSSSPKRSFRYQDKLLNLLSM 300

Query: 301 VFSQASGVPTGNHGLFHKYGIEALTLEAVKRERTQQQQFQEVGSMLRIIEGICRSLNNLL 360
           VFSQASGVPTGNHGLFHKYGIEALTLEAVKRERTQQQQFQEVGSMLRIIEGICRSLNNLL
Sbjct: 301 VFSQASGVPTGNHGLFHKYGIEALTLEAVKRERTQQQQFQEVGSMLRIIEGICRSLNNLL 360

Query: 361 ERFHQSFFFYLLVSNDRFVSIGDYMPSLALMAGALLIKAFIHYLSLYYTGDNDETEKSEE 420
           ERFHQSFFFYLLVSNDRFVSIGDYMPSLALMAGALLIKAFIHYLSLYYTGDNDETEKSEE
Sbjct: 361 ERFHQSFFFYLLVSNDRFVSIGDYMPSLALMAGALLIKAFIHYLSLYYTGDNDETEKSEE 420

Query: 421 TDAVETKQKAGNIDIGYFSVGIVLLVAHTLGALVVLLPQSKAVSNYLHEAELSTQFGLFS 480
           TDAVETKQKAGNIDIGYFSVGIVLLVAHTLGALVVLLPQSKAVSNYLHEAELSTQFGLFS
Sbjct: 421 TDAVETKQKAGNIDIGYFSVGIVLLVAHTLGALVVLLPQSKAVSNYLHEAELSTQFGLFS 480

Query: 481 LFVAVLVVALTLPAFCSLSGINGEALHVAVLLELGTVLLAVGMLNFSLGFSLSVLLVPFI 540
           LFVAVLVVALTLPAFCSLSGINGEALHVAVLLELGTVLLAVGMLNFSLGFSLSVLLVPFI
Sbjct: 481 LFVAVLVVALTLPAFCSLSGINGEALHVAVLLELGTVLLAVGMLNFSLGFSLSVLLVPFI 540

Query: 541 ILIRPAASRGAMFLSRLCCLLINPLVVLYCVLLALTWYLFPELAFKPMLNKALTATMDAL 600
           ILIRPAASRGAMFLSRLCCLLINPLVVLYCVLLALTWYLFPELAFKPMLNKALTATMDAL
Sbjct: 541 ILIRPAASRGAMFLSRLCCLLINPLVVLYCVLLALTWYLFPELAFKPMLNKALTATMDAL 600

Query: 601 TFSVVDSMIYGNWLFDMVSLIFVPCWVLLWVLLFPKTATNDRQTVGR 647
           TFSVVDSMIYGNWLFDMVSLIFVPCWVLLWVLLFPKTATNDRQTVGR
Sbjct: 601 TFSVVDSMIYGNWLFDMVSLIFVPCWVLLWVLLFPKTATNDRQTVGR 647
>ref|NP_572273.2| CG3033-PA [Drosophila melanogaster]
 gb|AAF46094.1| CG3033-PA [Drosophila melanogaster]
          Length = 674

 Score =  791 bits (2022), Expect = 0.0
 Identities = 312/654 (47%), Positives = 421/654 (63%), Gaps = 28/654 (4%)

Query: 4   MGLLTNPSISQKAKYCRKLVRYNTAICLTLYLLGVGFFCALPDANFNSGTYFSENALLPG 63
           MGLL++PSIS ++K    L R+   +C  LY+ GV +F  L    FN GTY SENAL PG
Sbjct: 1   MGLLSDPSISTQSKLVDGLARHVRKVCYALYVAGVAWFFCLALPEFNHGTYLSENALSPG 60

Query: 64  LVNSELEMETVNLVKSLSSELQRERENYPKGMPYPWLLAKMRRFGLETHTHNFTLNYPFG 123
           LV  E+ ++   L   L  ELQRER+++    P+ W+ AKM  FGLETHTHN+TL YPFG
Sbjct: 61  LVYPEIRIDANRLAIQLLEELQRERKDHLSTTPHAWIAAKMNEFGLETHTHNYTLRYPFG 120

Query: 124 GGKRFKGENVYGILRAPRIASTEAIVISVPYRPPETVHTDVSAGVPLMLAFADFARRKKY 183
           GGK + G+N+YGILRAPRIASTE IV + PYR   +VHTD+SA VPL+LAFADFARRK Y
Sbjct: 121 GGKEYHGKNIYGILRAPRIASTEGIVFAAPYRAASSVHTDISASVPLLLAFADFARRKNY 180

Query: 184 WAKDIIFLVTEQEQLGMQAWLEAYHGGDEGRILDSGLLR-----ARAGSIQAALNLEVQS 238
           WAKD+IFL+TEQEQLGMQAWLEAYH GD    L    LR     ARAGS+QAALN+EVQ 
Sbjct: 181 WAKDLIFLITEQEQLGMQAWLEAYHDGDRELDLSKAYLRPGNLPARAGSLQAALNIEVQD 240

Query: 239 LDISHINLKIEGLNGQLPNLDLHNLVQKLSSKNGIIAGYKQSSSSPKRSFR--YQDKLLN 296
           L+I H++++IEGLNG+LPNLD+ NLVQ++ ++ GI +GYKQ+    +R  +  ++     
Sbjct: 241 LEIDHVDVRIEGLNGKLPNLDMFNLVQRIMAREGIASGYKQAPRKKRRHSQSHFEQNFRQ 300

Query: 297 LLSMVFSQASGVPTGNHGLFHKYGIEALTLEAVKRERTQQQQFQEVGS----MLRIIEGI 352
           +L+M+ SQ+SGVPTGNHGLFH+Y I+ALT+ A  R  T        GS    +L+ IEGI
Sbjct: 301 MLTMLASQSSGVPTGNHGLFHRYRIDALTI-AANRRATHATLKGSPGSAAVPLLKAIEGI 359

Query: 353 CRSLNNLLERFHQSFFFYLLVSNDRFVSIGDYMPSLALMAGALLIKAFIHYLSLYYTGDN 412
            RSLNNLLERFHQSFFFY++VSNDR++SIGDYMP+L  +     +KA++ + +L  T  N
Sbjct: 360 ARSLNNLLERFHQSFFFYVIVSNDRYISIGDYMPALVALVACAFLKAYLTWSTLPAT--N 417

Query: 413 DETEKSE-------ETDAVETKQKAGNIDIGYFSVGIVLLVAHTLGALVVLLPQSKAVSN 465
            E EK+        +   +E   +    ++ Y SV I L     +G L  +LP    +  
Sbjct: 418 AELEKAAGWLREHEQEAELEENLEPDKFELPYGSVLIYLTATLLIGFLCNVLP----LQQ 473

Query: 466 YLHEAELSTQFGLFSLFVAVLVVALTLPAFCSLSGINGEALHVAVLLELGTVLLAVGMLN 525
           Y  E  +       S+   + ++   LP    L     E LHVA LL  G  L+ +G+LN
Sbjct: 474 YFLEIPMGAAPLTTSVLSFLSLIGFVLPFVVVLPPGGLELLHVAFLLIYGCALIVIGLLN 533

Query: 526 FSLGFSLSVLLVPFIILIRPAASRGAMFLS---RLCCLLINPLVVLYCVLLALTWYLFPE 582
           F+LG   +VL VP +I +          L    RL  L++NP++V+Y ++LA+T+Y FPE
Sbjct: 534 FALGLFAAVLTVPLVIALETKEENSRSTLRNTIRLATLVMNPMMVVYVIVLAMTFYQFPE 593

Query: 583 LAFKPMLNKALTATMDALTFSVVDSMIYGNWLFDMVSLIFVPCWVLLWVLLFPK 636
           L  + ++ +A TA MDA  + ++DS+IYGNWL+ ++  IF+P W++ W L   K
Sbjct: 594 LPVQKIMLRAATAAMDASAYGLIDSVIYGNWLYFVICTIFLPLWIICWTLSLSK 647
>ref|NP_034461.1| GPI anchor attachment protein 1 [Mus musculus]
 dbj|BAA82589.1| glycosylphosphatidylinositol anchor attachment 1 (GPAA1) [Mus
           musculus]
 dbj|BAA82591.1| glycosylphosphatidylinositol anchor attachment 1 (GPAA1) [Mus
           musculus]
 dbj|BAB03274.1| GPI anchor attachment protein [Mus musculus]
 dbj|BAB03275.1| GPI anchor attachment protein [Mus musculus]
 gb|AAH06697.1| GPI anchor attachment protein 1 [Mus musculus]
 dbj|BAC36840.1| unnamed protein product [Mus musculus]
          Length = 621

 Score =  729 bits (1864), Expect = 0.0
 Identities = 231/646 (35%), Positives = 337/646 (51%), Gaps = 38/646 (5%)

Query: 4   MGLLTNPSISQKAKYCRKLVRYNTAICLTLYLLGVGFFCALPDANFNSGTYFSENALLPG 63
           MGLL++P   ++    R ++R NT +C+  Y+ G+ +F AL        TY SENA+   
Sbjct: 1   MGLLSDP--VRRRALARIVLRLNTPLCVLSYVAGIAWFLALAFPPLTQRTYMSENAMGST 58

Query: 64  LVNSELEMETVNLVKSLSSELQRERENYPKGMPYPWLLAKMRRFGLETHTHNFTLNYPFG 123
           +V  +      +  +S + +    R+  P  +P  WL   MR  GLE +T +F+   PF 
Sbjct: 59  MVEEQF--VGGDRARSFARDFAAHRKK-PGALPVAWLERSMRSVGLEVYTQSFSRKLPFP 115

Query: 124 G--GKRF--KGENVYGILRAPRIASTEAIVISVPYRPPETVHTDVSAGVPLMLAFADFAR 179
               +R+   G NVYGILRAPR ASTE++V++VP  P  T    V   + L   F    R
Sbjct: 116 DETHERYMVSGTNVYGILRAPRSASTESLVLTVPCGPDATNSQAVGLLLALAAHF----R 171

Query: 180 RKKYWAKDIIFLVTEQEQLGMQAWLEAYHGGDEGRILDSGLLRARAGSIQAALNLEVQSL 239
            + YWAKDIIFLVT+ + LG +AWLEAYH  +   I  S  L+ RAG+IQAA+ LE+ S 
Sbjct: 172 GQIYWAKDIIFLVTDHDLLGTEAWLEAYHDINVTGI-QSSPLQGRAGAIQAAVALELSSD 230

Query: 240 DISHINLKIEGLNGQLPNLDLHNLVQKLSSKNGIIAGYKQSSSSPKRSFRYQ---DKLLN 296
            ++ +++ +EGLNGQLPNLDL NL Q    K G++    Q    P+     +     L  
Sbjct: 231 VVTSLDVTVEGLNGQLPNLDLLNLFQTFCQKGGLLCT-LQGKLQPQDWTSLEGPLQGLQT 289

Query: 297 LLSMVFSQASGVPTGNHGLFHKYGIEALTLEAVKRERTQQQQFQEVGSMLRIIEGICRSL 356
           LL MV  QASG P G HGLF +YG+EALTL  +   R  +     VG   + +EG+ R L
Sbjct: 290 LLLMVLRQASGRPHGPHGLFLRYGVEALTLRGINSFRQYKYDLATVG---KALEGMFRKL 346

Query: 357 NNLLERFHQSFFFYLLVSNDRFVSIGDYMPSLALMAGALLIKAFIHYLSLYYTGDNDETE 416
           N+LLER HQSFFFYLL +  RFVSIG YMP+   +   L +KA   ++ L+  G N E  
Sbjct: 347 NHLLERLHQSFFFYLLPALSRFVSIGLYMPATGFLLLVLGLKALELWMQLHQAGVNPEEA 406

Query: 417 KSEETDAVETKQKAGNIDIGYFSVGIVLLVAHTLGALVVLLP---QSKAVSNYLHEAELS 473
               +         G   +G  S+   LL++  +G  +  LP   Q  A  ++      +
Sbjct: 407 GKAPSPGTPLLPTQG---VGLASLTAPLLISQAMGLALYFLPVLGQHLATQHFPVAEAEA 463

Query: 474 TQFGLFSLFVAVLVVALTLPAFCS--LSGINGEALHVAVLLELGTVLLAVGMLNFSLGFS 531
               L +++VA L +        +  +      AL +  L+ L   L  + +LNFSLGF 
Sbjct: 464 VVLTLLAIYVAGLALPHNTHRVVNSQVPDRGWMALKLVALIYLALQLGCIALLNFSLGFL 523

Query: 532 LSVLLVPFIILIRPAASRGAMFLSRLCCLLINPLVVLYCVLLALTWYLFPELAFKPM-LN 590
           L+  +VP   L +P   R  ++ + L  ++ +P V L+  L     +L+ EL   P+ L 
Sbjct: 524 LAATMVPAAALAKPHGPR-TLYAALL--VVTSPAVTLFGSL-----FLWRELLEVPLSLA 575

Query: 591 KALTATMDALTFSVVDSMIYGNWLFDMVSLIFVPCWVLLWVLLFPK 636
           +     + AL   V++   YG  LF +++L   PCW+L W +LF K
Sbjct: 576 EGWQLFLTALAQGVLEHYTYGALLFPILALGLYPCWLLFWNVLFWK 621
>ref|XP_235447.1| similar to GPI anchor attachment protein 1 [Mus musculus] [Rattus
           norvegicus]
          Length = 671

 Score =  721 bits (1843), Expect = 0.0
 Identities = 230/693 (33%), Positives = 331/693 (47%), Gaps = 82/693 (11%)

Query: 4   MGLLTNPSISQKAKYCRKLVRYNTAICLTLYLLGVGFFCALPDANFNSGTYFSENALLPG 63
           MGLL++P   ++    R ++R NT +C+  Y+ G+ +F AL        TY SENA+   
Sbjct: 1   MGLLSDP--VRRRALARIVLRLNTPLCVLSYVAGIAWFLALAFPPLTQRTYMSENAMGST 58

Query: 64  LVNSELEMETVNLVKSLSSELQRERENYPKGMPYPWLLAKMRRFGLETHTHNFTLNYPF- 122
           +V  +      +  ++ + +    R+  P  +P  WL   MR  GLE +T +F+   PF 
Sbjct: 59  MVEEQF--VGGDRARNFARDFAAHRKK-PGALPVAWLERAMRSVGLEVYTQSFSRKLPFP 115

Query: 123 --------------GGGKRFKGENVYGILRAPRIASTEAIVISVPYRPPETVHTDVSAGV 168
                          G K   G NVYGILRAPR ASTE++V++VP  P  T    V   +
Sbjct: 116 DETHERYVLREMGVPGRKMVSGTNVYGILRAPRAASTESLVLTVPCGPDTTNSQAVGLLL 175

Query: 169 PLMLAFADFARRKKYWAKDIIFLVTEQEQLGMQAWLEAYHGGDEGRILDSGLLRARAGSI 228
            L   F    R + YWAKDIIFLVTE + LG +AWLEAYH  +   I  S  L+ RAG+I
Sbjct: 176 ALAAHF----RGQIYWAKDIIFLVTEHDLLGTEAWLEAYHDINVTGI-QSSPLQGRAGAI 230

Query: 229 QAALNLEVQSLDISHINLKIEGLNGQLPNLDLHNLVQKLSSKNGIIAGYKQSSSSPKRSF 288
           QAA+ LE+ S  ++ +++ +EGLNGQLPNLDL NL Q    K G++    Q    P+   
Sbjct: 231 QAAVALELSSDVVTSLDVTVEGLNGQLPNLDLLNLFQTFCQKGGLLCT-LQGKLQPQDWT 289

Query: 289 RYQ---DKLLNLLSMVFSQASGVPTGNHGLFHKYGIEALTLEAVKRERTQQQQFQEVGSM 345
             +     L  LL MV  QASG P G HGLF +YG+EALTL  +   R  +     VG  
Sbjct: 290 SLEGPLQGLQTLLLMVLRQASGRPHGPHGLFLRYGVEALTLRGINSFRQYKYDLVAVG-- 347

Query: 346 LRIIEGICRSLNNLLERFHQSFFFYLLVSNDRFVSIGDYMPSLALMAGALLIKAFIHYL- 404
            + +EG+ R LN+LLER HQSFFFYLL +  RFVSIG YMP+   +   L +K     + 
Sbjct: 348 -KALEGMFRKLNHLLERLHQSFFFYLLPALSRFVSIGLYMPATGFLLLVLGLKISSTLVL 406

Query: 405 -------------SLYYTGDNDETEKSEETDAVETKQKAGN------------------- 432
                         L+  G N E                                     
Sbjct: 407 DTHLWPNSDPFNCKLHEAGVNPEEAGKAPGPGSPPLATQVTSYSTALRMGSQRPQQCFLW 466

Query: 433 ---IDIGYFSVGIVLLVAHTLGALVVLLP---QSKAVSNYLHEAELSTQFGLFSLFVAVL 486
                +   S+   LL++  +G  +  LP   Q  A  ++      +    L +++VA L
Sbjct: 467 STLSSVSLASLMAPLLISQAMGLALYFLPVLGQHVAAQHFPVAEAEAVVLTLLAIYVAGL 526

Query: 487 VVALTLPAFCS--LSGINGEALHVAVLLELGTVLLAVGMLNFSLGFSLSVLLVPFIILIR 544
            +        S  +      AL +  L+ L   L  + +LNFSLGF L+  +VP   L +
Sbjct: 527 ALPHNTHRVVSSQVPDRGWMALKLVALIYLALQLGCIALLNFSLGFLLAATMVPAAALTK 586

Query: 545 PAASRGAMFLSRLCCLLINPLVVLYCVLLALTWYLFPELAFKPM-LNKALTATMDALTFS 603
           P   R  ++ + L  ++ +P V L+  L     +L+ EL   P+ L +     + AL   
Sbjct: 587 PHGPR-TLYAALL--VVTSPAVTLFGSL-----FLWRELQEVPLSLAEGWQLFLTALAQG 638

Query: 604 VVDSMIYGNWLFDMVSLIFVPCWVLLWVLLFPK 636
           V++   YG  LF +++L   PCW+L W +LF K
Sbjct: 639 VLEHYTYGALLFPILALGLYPCWLLFWNVLFWK 671
>ref|NP_003792.1| anchor attachment protein 1; anchor attachment protein 1 (Gaa1p,
           yeast) homolog; glycophosphatidylinositol anchor
           attachment 1 [Homo sapiens]
 dbj|BAA24035.1| hGAA1 [Homo sapiens]
 dbj|BAA82588.1| glycosylphosphatidylinositol anchor attachment 1 (GPAA1) [Homo
           sapiens]
 dbj|BAA82590.1| glycosylphosphatidylinositol anchor attachment 1 (GPAA1) [Homo
           sapiens]
 gb|AAH03171.1|AAH03171 anchor attachment protein 1 (Gaa1p, yeast) homolog [Homo sapiens]
 gb|AAH04129.1|AAH04129 anchor attachment protein 1 (Gaa1p, yeast) homolog [Homo sapiens]
          Length = 621

 Score =  701 bits (1791), Expect = 0.0
 Identities = 224/646 (34%), Positives = 325/646 (49%), Gaps = 38/646 (5%)

Query: 4   MGLLTNPSISQKAKYCRKLVRYNTAICLTLYLLGVGFFCALPDANFNSGTYFSENALLPG 63
           MGLL++P   ++    R ++R N  +C+  Y+ G+ +F AL        TY SENA+   
Sbjct: 1   MGLLSDP--VRRRALARLVLRLNAPLCVLSYVAGIAWFLALVFPPLTQRTYMSENAMGST 58

Query: 64  LVNSELEMETVNLVKSLSSELQRERENYPKGMPYPWLLAKMRRFGLETHTHNFTLNYPFG 123
           +V  +          +      R++      +P  WL   MR  GLE +T +F+   PF 
Sbjct: 59  MVEEQFAGGDRARAFARDFAAHRKKS---GALPVAWLERTMRSVGLEVYTQSFSRKLPFP 115

Query: 124 G--GKRF--KGENVYGILRAPRIASTEAIVISVPYRPPETVHTDVSAGVPLMLAFADFAR 179
               +R+   G NVYGILRAPR ASTE++V++VP     T    V   + L   F    R
Sbjct: 116 DETHERYMVSGTNVYGILRAPRAASTESLVLTVPCGSDSTNSQAVGLLLALAAHF----R 171

Query: 180 RKKYWAKDIIFLVTEQEQLGMQAWLEAYHGGDEGRILDSGLLRARAGSIQAALNLEVQSL 239
            + YWAKDI+FLVTE + LG +AWLEAYH  +    + S  L+ RAG+IQAA+ LE+ S 
Sbjct: 172 GQIYWAKDIVFLVTEHDLLGTEAWLEAYHDVNVTG-MQSSPLQGRAGAIQAAVALELSSD 230

Query: 240 DISHINLKIEGLNGQLPNLDLHNLVQKLSSKNGIIAGYKQSSSSPKRSFRYQ---DKLLN 296
            ++ +++ +EGLNGQLPNLDL NL Q    K G++    Q    P+           L  
Sbjct: 231 VVTSLDVAVEGLNGQLPNLDLLNLFQTFCQKGGLLCT-LQGKLQPEDWTSLDGPLQGLQT 289

Query: 297 LLSMVFSQASGVPTGNHGLFHKYGIEALTLEAVKRERTQQQQFQEVGSMLRIIEGICRSL 356
           LL MV  QASG P G+HGLF +Y +EALTL  +   R  +     VG   + +EG+ R L
Sbjct: 290 LLLMVLRQASGRPHGSHGLFLRYRVEALTLRGINSFRQYKYDLVAVG---KALEGMFRKL 346

Query: 357 NNLLERFHQSFFFYLLVSNDRFVSIGDYMPSLALMAGALLIKAFIHYLSLYYTGDNDETE 416
           N+LLER HQSFF YLL    RFVSIG YMP++  +   L +KA   ++ L+  G   E  
Sbjct: 347 NHLLERLHQSFFLYLLPGLSRFVSIGLYMPAVGFLLLVLGLKALELWMQLHEAGMGLEEP 406

Query: 417 KSEETDAVETKQKAGNIDIGYFSVGIVLLVAHTLGALVVLLP---QSKAVSNYLHEAELS 473
                 +V      G   +G  S+   LL++  +G  + +LP   Q  A  ++      +
Sbjct: 407 GGAPGPSVPLPPSQG---VGLASLVAPLLISQAMGLALYVLPVLGQHVATQHFPVAEAEA 463

Query: 474 TQFGLFSLFVAVLVVALTLPAFCSL--SGINGEALHVAVLLELGTVLLAVGMLNFSLGFS 531
               L +++ A L +        S         AL +  L+ L   L  + + NFSLGF 
Sbjct: 464 VVLTLLAIYAAGLALPHNTHRVVSTQAPDRGWMALKLVALIYLALQLGCIALTNFSLGFL 523

Query: 532 LSVLLVPFIILIRPAASRGAMFLSRLCCLLINPLVVLYCVLLALTWYLFPELAFKPM-LN 590
           L+  +VP   L +P   R  ++ + L  +L +P   L   L     +L+ EL   P+ L 
Sbjct: 524 LATTMVPTAALAKPHGPR-TLYAALL--VLTSPAATLLGSL-----FLWRELQEAPLSLA 575

Query: 591 KALTATMDALTFSVVDSMIYGNWLFDMVSLIFVPCWVLLWVLLFPK 636
           +     + AL   V++   YG  LF ++SL   PCW+L W +LF K
Sbjct: 576 EGWQLFLAALAQGVLEHHTYGALLFPLLSLGLYPCWLLFWNVLFWK 621
>gb|AAK77275.1| GH05723p [Drosophila melanogaster]
          Length = 561

 Score =  695 bits (1775), Expect = 0.0
 Identities = 276/568 (48%), Positives = 362/568 (63%), Gaps = 25/568 (4%)

Query: 4   MGLLTNPSISQKAKYCRKLVRYNTAICLTLYLLGVGFFCALPDANFNSGTYFSENALLPG 63
           MGLL++PSIS ++K    L R+   +C  LY+ GV +F  L    FN GTY SENAL PG
Sbjct: 1   MGLLSDPSISTQSKLVDGLARHVRKVCYALYVAGVAWFFCLALPEFNHGTYLSENALSPG 60

Query: 64  LVNSELEMETVNLVKSLSSELQRERENYPKGMPYPWLLAKMRRFGLETHTHNFTLNYPFG 123
           LV  E+ ++   L   L  ELQRER+++    P+ W+ AKM  FGLETHTHN+TL YPFG
Sbjct: 61  LVYPEIRIDANRLAIQLLEELQRERKDHLSTTPHAWIAAKMNEFGLETHTHNYTLRYPFG 120

Query: 124 GGKRFKGENVYGILRAPRIASTEAIVISVPYRPPETVHTDVSAGVPLMLAFADFARRKKY 183
           GGK + G+N+YGILRAPRIASTE IV + PYR   +VHTD+SA VPL+LAFADFARRK Y
Sbjct: 121 GGKEYHGKNIYGILRAPRIASTEGIVFAAPYRAASSVHTDISASVPLLLAFADFARRKNY 180

Query: 184 WAKDIIFLVTEQEQLGMQAWLEAYHGGDEGRILDSGLLR-----ARAGSIQAALNLEVQS 238
           WAKD+IFL+TEQEQLGMQAWLEAYH GD    L    LR     ARAGS+QAALN+EVQ 
Sbjct: 181 WAKDLIFLITEQEQLGMQAWLEAYHDGDRELDLSKAYLRPGNLPARAGSLQAALNIEVQD 240

Query: 239 LDISHINLKIEGLNGQLPNLDLHNLVQKLSSKNGIIAGYKQSSSSPKRSFR--YQDKLLN 296
           L+I H++++IEGLNG+LPNLD+ NLVQ++ ++ GI +GYKQ+    +R  +  ++     
Sbjct: 241 LEIDHVDVRIEGLNGKLPNLDMFNLVQRIMAREGIASGYKQAPRKKRRHSQSHFEQNFRQ 300

Query: 297 LLSMVFSQASGVPTGNHGLFHKYGIEALTLEAVKRERTQQQQFQEVGS----MLRIIEGI 352
           +L+M+ SQ+SGVPTGNHGLFH+Y I+ALT+ A  R  T        GS    +L+ IEGI
Sbjct: 301 MLTMLASQSSGVPTGNHGLFHRYRIDALTI-AANRRATHATLKGSPGSAAVPLLKAIEGI 359

Query: 353 CRSLNNLLERFHQSFFFYLLVSNDRFVSIGDYMPSLALMAGALLIKAFIHYLSLYYTGDN 412
            RSLNNLLERFHQSFFFY++VSNDR++SIGDYMP+L  +     +KA++ + +L  T  N
Sbjct: 360 ARSLNNLLERFHQSFFFYVIVSNDRYISIGDYMPALVALVACAFLKAYLTWSTLPAT--N 417

Query: 413 DETEKSE-------ETDAVETKQKAGNIDIGYFSVGIVLLVAHTLGALVVLLPQSKAVSN 465
            E EK+        +   +E   +    ++ Y SV I L     +G L  +LP    +  
Sbjct: 418 AELEKAAGWLREHEQEAELEENLEPDKFELPYGSVLIYLTATLLIGFLCNVLP----LQQ 473

Query: 466 YLHEAELSTQFGLFSLFVAVLVVALTLPAFCSLSGINGEALHVAVLLELGTVLLAVGMLN 525
           Y  E  +       S+   + ++   LP    L     E LHVA LL  G  L+ +G+LN
Sbjct: 474 YFLEIPMGAAPLTTSVLSFLSLIGFVLPFVVVLPPGGLELLHVAFLLIYGCALIVIGLLN 533

Query: 526 FSLGFSLSVLLVPFIILIRPAASRGAMF 553
           F+LG   +VL VP +I +       A  
Sbjct: 534 FALGLFAAVLTVPLVIALETKEENSAAR 561
>ref|NP_491700.2| Putative plasma membrane membrane protein family member, with at
           least 7 transmembrane domains, of eukaryotic origin
           [Caenorhabditis elegans]
 gb|AAK68360.2|AF039720_13 Hypothetical protein F33D11.9b [Caenorhabditis elegans]
          Length = 676

 Score =  677 bits (1729), Expect = 0.0
 Identities = 156/663 (23%), Positives = 275/663 (40%), Gaps = 82/663 (12%)

Query: 4   MGL-LTNPSISQKAKYCRKLVRYNTAICLTLYLLGVGFFCALPDANFNSGTYFSENALLP 62
           M L ++    + + K   K++++     +  Y+        L D      T  SE++L+P
Sbjct: 17  MALEISKDGGTTRPKILDKILKFRKVALIIAYIGAYLSAQWLFDPVNMEVTRISEHSLMP 76

Query: 63  GLVNSELEMETVNLVKSLSSELQRERENYPKGMPYPWLLAK-MRRFGLETHTHNFTLNYP 121
           GLV  + +   + +      +L R   + PK      L+       GLE  TH +     
Sbjct: 77  GLVTPKFDKSGIAI------QLYRRFSDLPKSKSQQELIHTIFSDLGLECFTHKWRSKV- 129

Query: 122 FGGGKRFKGENVYGILRAPRIASTEAIVISVPYRPPETVHTDVSAGVPLMLAFADFARRK 181
              G    GENVYG +R PR    EA +I V     E     +S     MLAF D+A+ +
Sbjct: 130 --AGNPMNGENVYGFIRGPRNDGAEAQMIVVQLGRSEKSRRMMSR----MLAFVDYAKDQ 183

Query: 182 KYWAKDIIFLVTE---------QEQLGMQAWLEAYH-----GGDEGRILDSGLLRARAGS 227
            YWA+DI+ +  +         +    + A+L  Y         +   +++  ++A+ G+
Sbjct: 184 VYWARDIVIVFVDGGEKNDSIEKAAFALDAFLLKYQKIEALNSKKSITVEADEIQAQTGA 243

Query: 228 IQAALNLEVQSLDI--SHI-NLKIEGLNGQLPNLDLHNLVQKLSSKNG----IIAGYKQS 280
           +   +  ++  + +   HI N++  GLNGQ  NLD+ N + K++         I G    
Sbjct: 244 LIGGVVYDLSGMAVKGQHIVNIQTNGLNGQQVNLDVFNGITKIADSKHHSRVAIFGTLHR 303

Query: 281 SSSPKRSFRYQDKLLNLLSMVFSQASGVPTGNHGLFHKYGIEALTLEAVKRERTQQQQFQ 340
            S+P          +  +  +++QA     G H +  KYG++ LT+  +  + +++Q  Q
Sbjct: 304 HSNPYME---YSPFIVPMRALYTQAFISIEGIHSVLGKYGVQGLTV-GLSHDYSEKQTGQ 359

Query: 341 EVGSMLRIIEGICRSLNNLLERFHQSFFFYLLVSNDRFVSIGDYMPSLALMAGALLIKAF 400
                   IE + R LNN+LER HQS+F Y+L  +  F SI  Y+  L ++   L+I A+
Sbjct: 360 -------FIEEVSRMLNNVLERLHQSYFMYVLADDLHFSSIAMYIIPLTILVSPLVISAY 412

Query: 401 IHYLSLYYTGDNDETEKSEETDAVETKQKAGNIDIGYFSVGIVLLVAHTLGALVVL-LPQ 459
             +  +             +         A ++ +G+F       V  T+G   VL   Q
Sbjct: 413 FEWTKI-------------QEFQFPVVHLAFHV-LGFFYYIATTYVFQTIGTTFVLQWMQ 458

Query: 460 SKAVSNYLHEAELSTQFGLFSLFVAVLVVALTLPAFCSLSGINGEALHVAVLLELGTVLL 519
              V     + + +  + L + F+   ++ L    F         ++ +  LLE   VL 
Sbjct: 459 WPFVGIDGCDGQFTPSWSLINSFLIFFMIPLGPYVFLKEPVRCVPSMRIVCLLETSLVLY 518

Query: 520 AVGMLNFSLGFSLSVLLVPFIILIRPAASRGAMFLSRLCCL-LINPLVVLYCVLL---AL 575
            + + NF L    +  +VP + L+   +S     + R   L ++NP+ VL  V +    +
Sbjct: 519 GICLTNFGLAILCTAFVVPIVFLMTYESSDRTRSIFRSSVLAILNPISVLAFVAINIPGM 578

Query: 576 TWYLFPELAFKPMLN----KALTATMDALTFSVVDSMIYGNWLFDMVSLIFVPCWVLLWV 631
              LFP ++    L      ALTA  + + F V          F ++     P    +W 
Sbjct: 579 FGQLFPTISQDSWLAAAQSIALTAIREDVEFKVNH--------FFLLCCFGYP----IWN 626

Query: 632 LLF 634
           +LF
Sbjct: 627 MLF 629
>pir||T46923 hypothetical protein DKFZp434E1512.1 - human
 emb|CAB75660.1| hypothetical protein [Homo sapiens]
 gb|AAH06383.1|AAH06383 Unknown (protein for MGC:12663) [Homo sapiens]
          Length = 499

 Score =  568 bits (1451), Expect = e-160
 Identities = 189/519 (36%), Positives = 267/519 (51%), Gaps = 29/519 (5%)

Query: 127 RFKGENVYGILRAPRIASTEAIVISVPYRPPETVHTDVSAGVPLMLAFADFARRKKYWAK 186
              G NVYGILRAPR ASTE++V++VP     T    V   + L   F    R + YWAK
Sbjct: 1   MVSGTNVYGILRAPRAASTESLVLTVPCGSDSTNSQAVGLLLALAAHF----RGQIYWAK 56

Query: 187 DIIFLVTEQEQLGMQAWLEAYHGGDEGRILDSGLLRARAGSIQAALNLEVQSLDISHINL 246
           DI+FLVTE + LG +AWLEAYH  +    + S  L+ RAG+IQAA+ LE+ S  ++ +++
Sbjct: 57  DIVFLVTEHDLLGTEAWLEAYHDVNVTG-MQSSPLQGRAGAIQAAVALELSSDVVTSLDV 115

Query: 247 KIEGLNGQLPNLDLHNLVQKLSSKNGIIAGYKQSSSSPKRSFRYQ---DKLLNLLSMVFS 303
            +EGLNGQLPNLDL NL Q    K G++    Q    P+           L  LL MV  
Sbjct: 116 AVEGLNGQLPNLDLLNLFQTFCQKGGLLCT-LQGKLQPEDWTSLDGPLQGLQTLLLMVLR 174

Query: 304 QASGVPTGNHGLFHKYGIEALTLEAVKRERTQQQQFQEVGSMLRIIEGICRSLNNLLERF 363
           QASG P G+HGLF +Y +EALTL  +   R  +     VG   + +EG+ R LN+LLER 
Sbjct: 175 QASGRPHGSHGLFLRYRVEALTLRGINSFRQYKYDLVAVG---KALEGMFRKLNHLLERL 231

Query: 364 HQSFFFYLLVSNDRFVSIGDYMPSLALMAGALLIKAFIHYLSLYYTGDNDETEKSEETDA 423
           HQSFF YLL    RFVSIG YMP++  +   L +KA   ++ L+  G   E        +
Sbjct: 232 HQSFFLYLLPGLSRFVSIGLYMPAVGFLLLVLGLKALELWMQLHEAGMGLEEPGGAPGPS 291

Query: 424 VETKQKAGNIDIGYFSVGIVLLVAHTLGALVVLLP---QSKAVSNYLHEAELSTQFGLFS 480
           V      G   +G  S+   LL++  +G  + +LP   Q  A  ++      +    L +
Sbjct: 292 VPLPPSQG---VGLASLVAPLLISQAMGLALYVLPVLGQHVATQHFPVAEAEAVVLTLLA 348

Query: 481 LFVAVLVVALTLPAFCSL--SGINGEALHVAVLLELGTVLLAVGMLNFSLGFSLSVLLVP 538
           ++ A L +        S         AL +  L+ L   L  + + NFSLGF L+  +VP
Sbjct: 349 IYAAGLALPHNTHRVVSTQAPDRGWMALKLVALIYLALQLGCIALTNFSLGFLLATTMVP 408

Query: 539 FIILIRPAASRGAMFLSRLCCLLINPLVVLYCVLLALTWYLFPELAFKPM-LNKALTATM 597
              L +P   R  ++ + L  +L +P   L   L     +L+ EL   P+ L +     +
Sbjct: 409 TAALAKPHGPR-TLYAALL--VLTSPAATLLGSL-----FLWRELQEAPLSLAEGWQLFL 460

Query: 598 DALTFSVVDSMIYGNWLFDMVSLIFVPCWVLLWVLLFPK 636
            AL   V++   YG  LF ++SL   PCW+L W +LF K
Sbjct: 461 AALAQGVLEHHTYGALLFPLLSLGLYPCWLLFWNVLFWK 499
>ref|NP_197414.1| GPAA1 - like protein; protein id: At5g19130.1 [Arabidopsis
           thaliana]
          Length = 696

 Score =  548 bits (1399), Expect = e-154
 Identities = 184/713 (25%), Positives = 282/713 (38%), Gaps = 126/713 (17%)

Query: 10  PSISQKAKYCRK---LVRYNTAICLTLYLLGVGFFCALPDANFNSGTYFSENALLPGLVN 66
           P I  +    R    L+ ++    +     GV     L        TY SENAL+PG   
Sbjct: 19  PKIKPRP-IVRLGIFLIAHSPVFSVVFSAAGVLA--LLLLPLLAKNTYISENALMPGSAR 75

Query: 67  SELEMETVNLVKSLSSELQRERENYPKGMPYPWLLAKMRRFGLETHTHNF--------TL 118
           S L    V+    L  +++  R N+ +G     +   M   G E     F         L
Sbjct: 76  SMLSNRDVSDGSKLVKDIKNFRLNH-EGQVQKLIGKYMSDMGAEVSYQKFHPEGNQFHPL 134

Query: 119 NYPFGGGKRF----------KGENVYGILRAPRIASTEAIVISVPYRPPE-TVHTDVSAG 167
           ++ F G   +           G NV GI+RAPR    E+IV+  PY       + D+S G
Sbjct: 135 HF-FSGPDSYTLLENVSCASYGVNVAGIIRAPRGDGKESIVLVTPYDFINGGDYEDLSLG 193

Query: 168 VPLMLAFADFARRKKYWAKDIIFLVTEQ---EQLGMQAWLEAYHGG----------DEGR 214
           +  + +      R  + +KDII+LV +    +   + AWL  YH            DE  
Sbjct: 194 I--VSSLFSLLSRVTWLSKDIIWLVADSRYGDYRPVAAWLTEYHSPSFKVSDLLKCDEQN 251

Query: 215 ILDSGLLRARAGSIQAALNLEVQSLDISH---INLKIEGLNGQLPNLDLHNLVQKLSSKN 271
             D+     RAG++ AAL L+V          +++  E  NGQ+PNLDL N+V  L+   
Sbjct: 252 TADN---FRRAGTMAAALVLKVDGRSEKFEDTLSIYAEASNGQMPNLDLINVVNYLAVHR 308

Query: 272 -------------------------GIIAGYKQSSSSPKRSF------RYQDKLLNLLSM 300
                                        G      +P           Y +    L S 
Sbjct: 309 QGFYVKVEKVVSLLSSSWLKIFGEIFEAVGKLAHMLNP-DWNFGIPAADYLEGSATLASS 367

Query: 301 VFSQASGVPTGNHGLFHKYGIEALTLEAVKRER----TQQQQFQEVGSMLRIIEGICRSL 356
           ++SQA G+PTG HG F  Y ++A+TL+   R      T+Q  F   G+  R++EG  RS+
Sbjct: 368 LYSQALGIPTGPHGAFRDYQVDAITLKVSPRFPPDSKTRQHDFFLRGA--RLLEGTIRSV 425

Query: 357 NNLLERFHQSFFFYLLVSNDRFVSIGDYMPSLALMAGALLIKAFIHYLSLYYTGDNDETE 416
           NNLLE+FHQSFF Y+L S  +F+S+G YM + AL+   L + A     SLY  G    T 
Sbjct: 426 NNLLEKFHQSFFLYMLTSPSKFISVGVYMIAFALLVAPLPMVA----ASLYIDGCKSLTN 481

Query: 417 KSEETDAVETKQKAGNIDIGYFSVGIVLLVAHTLGALVVLLPQSKA-VSNYLHEAELSTQ 475
            +          K       +      +   H LG +V LLP     V         S  
Sbjct: 482 STHNPTENFKSWK-------WLDAAKQVFTLHLLGFIVTLLPYFICQVPGQHSPTNRSIM 534

Query: 476 FGLFSLFVAVLVVALTL----PAFCSLSGINGEALHVAVLLELGTVLLAVGMLNFSLGFS 531
           +G  S  + +L+  +T+    P    L G N   L    +      L  + ++NF+    
Sbjct: 535 WGTTSSSL-LLITFVTMPGCSPFSSRLHGTNWAILKSVTISAAFIGLCLMSIINFATAEI 593

Query: 532 LSVLLVPFIILIRPAASRGAMFLSRLCCLLINPLVVLYCVLLALTWYLFPELAFKPMLNK 591
            ++LLVP  ++ +P   + A+   RL  LL       +C ++ LT      + F  M   
Sbjct: 594 GALLLVPTCLMAQPI--KPALRSRRLKSLL-----GAFCSIVLLT------IGFPVMFFA 640

Query: 592 ALTATMDALTFSVVDSMIYGNWLFDM----------VSLIFVPCWVLLWVLLF 634
                +      +     +  WL  +          + ++ +PCW+L   +LF
Sbjct: 641 ISKGLLGEGLVGLSLGGEFWTWLESLWAWKSATYLYIGMVHLPCWLLCLCILF 693
>gb|AAO00773.1| GPAA1 - like protein [Arabidopsis thaliana]
          Length = 699

 Score =  546 bits (1392), Expect = e-154
 Identities = 183/715 (25%), Positives = 280/715 (38%), Gaps = 127/715 (17%)

Query: 10  PSISQKAKYCRK---LVRYNTAICLTLYLLGVGFFCALPDANFNSGTYFSENALLPGLVN 66
           P I  +    R    L+ ++    +     GV     L        TY SENAL+PG   
Sbjct: 19  PKIKPRP-IVRLGIFLIAHSPVFSVVFSAAGVLA--LLLLPLLAKNTYISENALMPGSAR 75

Query: 67  SELEMETVNLVKSLSSELQRERENYPKG--MPYPWLLAKMRRFGLETHTHNF-------- 116
           S L    V+    L  +++  R N+          +   M   G E     F        
Sbjct: 76  SMLSNRDVSDGSKLVKDIKNFRLNHEGQGVEVQKLIGKYMSDMGAEVSYQKFHPEGNQFH 135

Query: 117 TLNYPFGGGKRF----------KGENVYGILRAPRIASTEAIVISVPYRPPE-TVHTDVS 165
            L++ F G   +           G NV GI+RAPR    E+IV+  PY       + D+S
Sbjct: 136 PLHF-FSGPDSYTLLENVSCASYGVNVAGIIRAPRGDGKESIVLVTPYDFINGGDYEDLS 194

Query: 166 AGVPLMLAFADFARRKKYWAKDIIFLVTEQ---EQLGMQAWLEAYHGG----------DE 212
            G+  + +      R  + +KDII+LV +    +   + AWL  YH            DE
Sbjct: 195 LGI--VSSLFSLLSRVTWLSKDIIWLVADSRYGDYRPVAAWLTEYHSPSFKVSDLLKCDE 252

Query: 213 GRILDSGLLRARAGSIQAALNLEVQSLDISH---INLKIEGLNGQLPNLDLHNLVQKLSS 269
               D+     RAG++ AAL L+V          +++  E  NGQ+PNLDL N+V  L+ 
Sbjct: 253 QNTADN---FRRAGTMAAALVLKVDGRSEKFEDTLSIYAEASNGQMPNLDLINVVNYLAV 309

Query: 270 KN-------------------------GIIAGYKQSSSSPKRSF------RYQDKLLNLL 298
                                          G      +P           Y +    L 
Sbjct: 310 HRQGFYVKVEKVVSLLSSSWLKIFGEIFKAVGKLAHMLNP-DWNFGIPAADYLEGSATLA 368

Query: 299 SMVFSQASGVPTGNHGLFHKYGIEALTLEAVKRER----TQQQQFQEVGSMLRIIEGICR 354
           S ++SQA G+PTG HG F  Y ++A+TL+   R      T+Q  F   G+  R++EG  R
Sbjct: 369 SSLYSQALGIPTGPHGAFRDYQVDAITLKVSPRFPPDSKTRQHDFFLRGA--RLLEGTIR 426

Query: 355 SLNNLLERFHQSFFFYLLVSNDRFVSIGDYMPSLALMAGALLIKAFIHYLSLYYTGDNDE 414
           S+NNLLE+FHQSFF Y+L S  +F+S+G YM + AL+   L + A     SLY  G    
Sbjct: 427 SVNNLLEKFHQSFFLYMLTSPSKFISVGVYMIAFALLVAPLPMVA----ASLYIDGCKSL 482

Query: 415 TEKSEETDAVETKQKAGNIDIGYFSVGIVLLVAHTLGALVVLLPQSKA-VSNYLHEAELS 473
           T  +          K       +      +   H LG +V LLP     V         S
Sbjct: 483 TNSTHNPTENFKSWK-------WLDAAKQVFTLHLLGFIVTLLPYFICQVPGQHSPTNRS 535

Query: 474 TQFGLFSLFVAVLVVALTL----PAFCSLSGINGEALHVAVLLELGTVLLAVGMLNFSLG 529
             +G  S  + +L+  +T+    P    L G N   L    +      L  + ++NF+  
Sbjct: 536 IMWGTTSSSL-LLITFVTMPGCSPFSSRLHGTNWAILKSVTISAAFIGLCLMSIINFATA 594

Query: 530 FSLSVLLVPFIILIRPAASRGAMFLSRLCCLLINPLVVLYCVLLALTWYLFPELAFKPML 589
              ++LLVP  ++ +P   + A+   RL  LL       +C ++ LT      + F  M 
Sbjct: 595 EIGALLLVPTCLMAQPI--KPALRSRRLKSLL-----GAFCSIVLLT------IGFPVMF 641

Query: 590 NKALTATMDALTFSVVDSMIYGNWLFDM----------VSLIFVPCWVLLWVLLF 634
                  +      +     +  WL  +          + ++ +PCW+L   +LF
Sbjct: 642 FAISKGLLGEGLVGLSLGGEFWTWLESLWAWKSATYLYIGMVHLPCWLLCLCILF 696
>pir||T32771 hypothetical protein F33D11.9b - Caenorhabditis elegans
          Length = 885

 Score =  539 bits (1375), Expect = e-151
 Identities = 122/519 (23%), Positives = 217/519 (41%), Gaps = 62/519 (11%)

Query: 4   MGL-LTNPSISQKAKYCRKLVRYNTAICLTLYLLGVGFFCALPDANFNSGTYFSENALLP 62
           M L ++    + + K   K++++     +  Y+        L D      T  SE++L+P
Sbjct: 279 MALEISKDGGTTRPKILDKILKFRKVALIIAYIGAYLSAQWLFDPVNMEVTRISEHSLMP 338

Query: 63  GLVNSELEMETVNLVKSLSSELQRERENYPKGMPYPWLLAK-MRRFGLETHTHNFTLNYP 121
           GLV  + +   + +      +L R   + PK      L+       GLE  TH +     
Sbjct: 339 GLVTPKFDKSGIAI------QLYRRFSDLPKSKSQQELIHTIFSDLGLECFTHKWRSKV- 391

Query: 122 FGGGKRFKGENVYGILRAPRIASTEAIVISVPYRPPETVHTDVSAGVPLMLAFADFARRK 181
              G    GENVYG +R PR    EA +I V     E     +S     MLAF D+A+ +
Sbjct: 392 --AGNPMNGENVYGFIRGPRNDGAEAQMIVVQLGRSEKSRRMMSR----MLAFVDYAKDQ 445

Query: 182 KYWAKDIIFLVTE---------QEQLGMQAWLEAYH-----GGDEGRILDSGLLRARAGS 227
            YWA+DI+ +  +         +    + A+L  Y         +   +++  ++A+ G+
Sbjct: 446 VYWARDIVIVFVDGGEKNDSIEKAAFALDAFLLKYQKIEALNSKKSITVEADEIQAQTGA 505

Query: 228 IQAALNLEVQSLDI--SHI-NLKIEGLNGQLPNLDLHNLVQKLSSKNG----IIAGYKQS 280
           +   +  ++  + +   HI N++  GLNGQ  NLD+ N + K++         I G    
Sbjct: 506 LIGGVVYDLSGMAVKGQHIVNIQTNGLNGQQVNLDVFNGITKIADSKHHSRVAIFGTLHR 565

Query: 281 SSSPKRSFRYQDKLLNLLSMVFSQASGVPTGNHGLFHKYGIEALTLEAVKRERTQQQQFQ 340
            S+P          +  +  +++QA     G H +  KYG++ LT+  +  + +++Q  Q
Sbjct: 566 HSNPYME---YSPFIVPMRALYTQAFISIEGIHSVLGKYGVQGLTV-GLSHDYSEKQTGQ 621

Query: 341 EVGSMLRIIEGICRSLNNLLERFHQSFFFYLLVSNDRFVSIGDYMPSLALMAGALLIKAF 400
                   IE + R LNN+LER HQS+F Y+L  +  F SI  Y+  L ++   L+I A+
Sbjct: 622 -------FIEEVSRMLNNVLERLHQSYFMYVLADDLHFSSIAMYIIPLTILVSPLVISAY 674

Query: 401 IHYLSLYYTGDNDETEKSEETDAVETKQKAGNIDIGYFSVGIVLLVAHTLGALVVL-LPQ 459
             +  +             +         A ++ +G+F       V  T+G   VL   Q
Sbjct: 675 FEWTKI-------------QEFQFPVVHLAFHV-LGFFYYIATTYVFQTIGTTFVLQWMQ 720

Query: 460 SKAVSNYLHEAELSTQFGLFSLFVAVLVVALTLPAFCSL 498
              V     + + +  + L + F+   ++ L    F   
Sbjct: 721 WPFVGIDGCDGQFTPSWSLINSFLIFFMIPLGPYVFLKT 759
 Score = 90.3 bits (222), Expect = 1e-16
 Identities = 24/107 (22%), Positives = 39/107 (36%), Gaps = 23/107 (21%)

Query: 539 FIILIRPAASR---GAMFLSRLCCL-LINPLVVLYCVLL---ALTWYLFPELAFKPMLN- 590
            I  + P           + R   L ++NP+ VL  V +    +   LFP ++    L  
Sbjct: 744 LIFFMIPLGPYVFLKTRSIFRSSVLAILNPISVLAFVAINIPGMFGQLFPTISQDSWLAA 803

Query: 591 ---KALTATMDALTFSVVDSMIYGNWLFDMVSLIFVPCWVLLWVLLF 634
               ALTA  + + F V          F ++     P    +W +LF
Sbjct: 804 AQSIALTAIREDVEFKVNH--------FFLLCCFGYP----IWNMLF 838
>dbj|BAC01259.1| putative GPAA1 - like protein [Oryza sativa (japonica
           cultivar-group)]
          Length = 718

 Score =  531 bits (1355), Expect = e-149
 Identities = 178/716 (24%), Positives = 287/716 (39%), Gaps = 142/716 (19%)

Query: 25  YNTAICLTLYLLGVGFFCALPDANFNSGTYFSENALLPGLVNSELEMETVN----LVKSL 80
             +A+C T  ++ + F  +L        TY SENAL+PG  N+    E V       K +
Sbjct: 29  LFSAVCCTAGIIALLFLPSLA-----KNTYLSENALIPGSANTLFSTEDVQEANRFAKGI 83

Query: 81  SSELQRERENYPKGMPYPWLLAKMRRFGLETHTHNFTLNY-------------------P 121
            + +   R          ++  + +  G E + H F  +                    P
Sbjct: 84  EAAIGESRG--GTTEIPKFIAQQTKNLGAEVYYHEFLPDSKCFHPLKFFTSMTNNMAAKP 141

Query: 122 FGGGKRFKGENVYGILRAPRIASTEAIVISVPYRPPETVHTDVSAGVPLMLAFADFARRK 181
            G    F G N  GI+RAPR    EAIV+  PY   +    ++   + L  +      R 
Sbjct: 142 NGTYTNF-GINTVGIIRAPRGDGKEAIVLVTPYNSQKVTPNEL-LSLALGFSVFSLLSRA 199

Query: 182 KYWAKDIIFLVTEQ---EQLGMQAWLEAYHGG---------------------DEGRILD 217
            + +KDI++L  +    E   + +WL  YH                             +
Sbjct: 200 AWLSKDIVWLSADSQFGEYSAVSSWLNQYHNPMFLSHPVNLDTKIYGANQILYKPDGTAE 259

Query: 218 SGLLRA--RAGSIQAALNLEVQSL----DISHINLKIEGLNGQLPNLDLHNLVQKLSSKN 271
              L A  RAG++ AAL  +V       D   + +  E  NGQ+PNLDL N+V  L+   
Sbjct: 260 KAELMAFKRAGTMAAALIFKVGETRKYGDRDSVTMYAEASNGQMPNLDLLNVVHYLAVHR 319

Query: 272 -------------------------GIIAGYKQSSSSPKRSF-----RYQDKLLNLLSMV 301
                                        G      +P          Y +   NL S +
Sbjct: 320 QGFRVNVETFNSLLSSSWLRVIAEVFQNLGSLLRKINPDWKLDVTVPDYVEGTANLASSM 379

Query: 302 FSQASGVPTGNHGLFHKYGIEALTLE-----AVKRERTQQQQFQEVGSMLRIIEGICRSL 356
           ++QA GVPTG+HG F  Y ++A++LE      +K E  +       G   R+ EG+ RS+
Sbjct: 380 YNQALGVPTGSHGAFRDYQVDAVSLEFAPAFHLKNENAKSSFLLRGG---RLTEGVVRSV 436

Query: 357 NNLLERFHQSFFFYLLVSNDRFVSIGDYMPSLALMAGALLIKAFIHYLSLYYTGDNDETE 416
           NNLLE+FHQSFF Y L +  +F+S+G YM   AL+   L I A          G +    
Sbjct: 437 NNLLEKFHQSFFLYFLTAPSKFISVGVYMIPFALLLAPLPIVA------AALAGGSKTKG 490

Query: 417 KSEETDAVETKQKAGNIDI-----GYFSVGIVLLVAHTLGALVVLLPQSKAVSNYLHEAE 471
           K    D  +TK  A ++ +      +     VLL+      LV LLP   +         
Sbjct: 491 KL--EDECKTKGNADDLQMEGGSWKWLKSARVLLIIQFWAVLVSLLPYYISQ----IPGA 544

Query: 472 LSTQFGLF--SLFVAVLVVALTLPAFCSLSGINGEALHVAVLLELGTVLLAVGMLNFSLG 529
           +  Q+ +    L + +L++   +    S +G+  + L   ++  +   +  + ++NF+  
Sbjct: 545 MPIQYAVIWAVLSITILIILYAMFGSPSRAGVEWKLLKATMITSITIGMGLMSIINFATA 604

Query: 530 FSLSVLLVPFIILIRPAASRGAM-FLSRLCCLLINPLVVLYCVLLALTWYLFPELAFKPM 588
              +++L+P  +  RP  ++  M FL R   L  N         + LT   FP  AF  +
Sbjct: 605 QLGALILIPMCLFSRPLRAQLEMNFLPRTVLLASN---------ILLTVLGFPPAAF--L 653

Query: 589 LNKALTATMDALTFSVV-DSMIYGNWLFDMVS-------LIFVPCWVLL-WVLLFP 635
           + K L+    + T  +V D  ++  +L++  S       L+ +PCW+L   VLL P
Sbjct: 654 IMKGLSK--GSWTVDIVGDFWLWMEFLWEWSSATYLYVFLVHLPCWLLCIHVLLHP 707
>ref|NP_593498.1| putative glycosylphosphatidylinositol anchor attachment protein
           [Schizosaccharomyces pombe]
 emb|CAB65611.1| putative glycosylphosphatidylinositol anchor attachment protein
           [Schizosaccharomyces pombe]
          Length = 581

 Score =  499 bits (1272), Expect = e-139
 Identities = 143/552 (25%), Positives = 251/552 (44%), Gaps = 68/552 (12%)

Query: 22  LVRYNTAICLTLYLLGVGFFCALPDANFNSGTYFSENALLPGLVNSELEME---TVNLVK 78
           L R+   + L+L L+G+ +   LP        + SE+ALLPG VN+  E     TV+   
Sbjct: 15  LQRHLFFLQLSLTLIGLSWIFILPRNEIIDRLHVSESALLPGQVNTYFENRYSKTVSSSL 74

Query: 79  SLSSELQRERENYPKGMPYPWLLAKMRRFGLETHTHNFTLNYPFGGGKRFKGENVYGILR 138
           + ++       +      Y  L       GL T   N+++N P   G  F G N    LR
Sbjct: 75  TAANTWSHLDASVGTNTMYDDLEQIFTAMGLPTQKQNYSINIP---GSEFNGSNFITTLR 131

Query: 139 APRIASTEAIVISVPYRPPETVHTDVSAGVPLMLAFADFARRKKYWAKDIIFLVTEQEQL 198
           APR  +TE++++ VP++  + +     AGV L ++   + +    W+KDII ++ +    
Sbjct: 132 APRGDATESLLLCVPWK--DHIGQYNEAGVALAISLLKYFQGWSLWSKDIILVIFDDPVY 189

Query: 199 GMQAWLEAYHGGDEGRILDSGLLRARAGSIQAALNLEVQSLDISH--INLKIEGLNGQLP 256
           G  ++L +Y       I  +  L+ R+GSIQA L+LE+ + + +   + +  +  NGQLP
Sbjct: 190 GPSSFLTSYFDQTTPYISYT-PLKIRSGSIQAGLSLELVTTENNSDVLEVLYQATNGQLP 248

Query: 257 NLDLHNLVQKLSSKNG----IIAGYKQSSSSPKRSFRYQDKLLNLLSMVFSQASGVPTGN 312
           NLDL N + ++  ++      + GY   ++S      Y  +L +L   + +QA    T  
Sbjct: 249 NLDLFNTISRIFMQHFNYPLRLQGYDFHANSG---SSYTSRLKSLWMGMLTQAVSNVTSA 305

Query: 313 HGLFHKYGIEALTLEAVKRERTQQQQFQEVGSMLRIIEGICRSLNNLLERFHQSFFFYLL 372
           H LF +Y I+ LTL    ++      F+      + IE   RSLNNLLE  HQSFFFY +
Sbjct: 306 HALFPQYRIDMLTLRMKVKDPFSFDMFR----FGQAIESTFRSLNNLLEHLHQSFFFYFI 361

Query: 373 VSNDRFVSIGDYMPSLALMAGALLIKAFIHYLSLYYTGDNDETEKSEETDAVETKQKAGN 432
           + +  F+SIG+YMPS+ ++A + ++ A+ H+++     D                 +  +
Sbjct: 362 LDHLHFISIGNYMPSILILAASFMLGAYRHWINHEKKID---------------LWRPFS 406

Query: 433 IDIG--YFSVGIVLLVAHTLGALVVLLPQSKAVSNYLHEAELSTQFGLFSLFVAVLVVAL 490
             +   + ++    LV+                         S+      +F+ +++  +
Sbjct: 407 FWLFSIFCTIAAYYLVS-------------------------SSTKITVFIFLYLMLTFI 441

Query: 491 TLPAFCSLSGINGEALHVAVLLELGTVLLAVGMLNFSLGFSLSVLLVPFIILIRPAASRG 550
            +     ++  + E +    L+     +  V  LNFSL F +++LLVP     +  + R 
Sbjct: 442 GIIFSTFMTSEDAELVLSYDLMSKSLFISVVSTLNFSLSFVVAILLVPL----QFISFRF 497

Query: 551 AMFLSRLCCLLI 562
              LS L  +L 
Sbjct: 498 NRRLSLLFAVLT 509
>gb|EAA16082.1| hypothetical protein [Plasmodium yoelii yoelii]
          Length = 489

 Score =  262 bits (665), Expect = 1e-68
 Identities = 58/255 (22%), Positives = 111/255 (42%), Gaps = 36/255 (14%)

Query: 148 IVISVPYRPPETVHTDVSAGVPLMLAFADFARRKKYWAKDIIFLVTEQE---QLGMQAWL 204
           +VI+  Y+  +  H+ V       L   ++     Y +KDIIFL T +E    LG++ ++
Sbjct: 137 VVINFDYKERKYFHSLVV-----GLTLINYFLNANYMSKDIIFLFTNKELLYSLGVKNFI 191

Query: 205 EAYHGGDEGRILDSGLLRARAGSIQAALNLEVQSLDISHINLKIEGLNGQLPNLDLHNLV 264
           E Y+ G+            R    ++++ +E +S+  S+I +  E LNG LPN DL  L+
Sbjct: 192 EHYYYGNTEN---------RKVLTRSSIIIEFESIYPSNIEINYESLNGMLPNQDLILLL 242

Query: 265 QKLSSKNGIIAGYKQSSSSPKRSFRYQDKLLNL-LSMVFSQASGVPTGNHGLFHKYGIEA 323
           +   +   I          P ++      +LN+ L   + +        H  F +  I +
Sbjct: 243 RNELNHYNI----------PMKTDPVYHAILNVALEKKYEKG-------HIYFLRENIPS 285

Query: 324 LTLEAVKRERTQQQQFQEVGSMLRIIEGICRSLNNLLERFHQSFFFYLLVSNDRFVSIGD 383
            T+  V +   +++      +  + ++   RS +N  E F  S  FY   +  ++V I  
Sbjct: 286 FTITGVSKVPLKRKMINL-FNFTKSLQSFLRSQSNTHEGFCHSTNFYFFNTIKKYVPISL 344

Query: 384 YMPSLALMAGALLIK 398
           Y+  + L+    ++K
Sbjct: 345 YVFCVYLICSYCILK 359
>ref|NP_705572.1| hypothetical protein [Plasmodium falciparum 3D7]
 emb|CAD52809.1| hypothetical protein [Plasmodium falciparum 3D7]
          Length = 810

 Score =  246 bits (624), Expect = 1e-63
 Identities = 63/271 (23%), Positives = 104/271 (38%), Gaps = 48/271 (17%)

Query: 148 IVISVPYRPPETVHTDVSAGVPLMLAFADFARRKKYWAKDIIFLVTEQE---QLGMQAWL 204
           +VI+  ++  +  H+ V  G+ LM  F     +  Y +KD+ FL T +E    LG+Q ++
Sbjct: 138 VVINFDFKERKYFHS-VIIGLTLMEHF----SKCNYMSKDVTFLFTNKELLYSLGVQEFI 192

Query: 205 EAYHGGDEGRILDSGLLRARAGSIQAALNLEVQSLDISHINLKIEGLNGQLPNLDLHNLV 264
           + Y   +  RI   G    R+ +I     +E  S+  S+I +  EGLNG LPN DL  L+
Sbjct: 193 QKYFYNNTNRI---GKKIIRSSTI-----IEFDSIYPSYIKINYEGLNGMLPNQDLILLL 244

Query: 265 QKLSSKNGIIAGYKQSSSSPKRSFRYQDKLLNLLSMVFSQASGVPTGNHGLFHKY----- 319
                           S   K    +       L   +          H  F +Y     
Sbjct: 245 TNE---------LHFYSIPIKMELTHGSIFDMALEKNYENG-------HIYFLRYKKKYE 288

Query: 320 ----------GIEALTLEAVKRERTQQQQFQEVGSMLRIIEGICRSLNNLLERFHQSFFF 369
                      I A T     +   + +      ++ + ++   RS +N  E F  S  F
Sbjct: 289 YIRDDNDEIKNIPAFTATGGSKVPIRNKMINL-FNLTKALQSYLRSQSNTHEGFCHSSNF 347

Query: 370 YLLVSNDRFVSIGDYMPSLALMAGALLIKAF 400
           Y   +  R + I  Y  S+ L+    ++K F
Sbjct: 348 YFFNTFRRHIPISIYCYSVYLICAYSIMKLF 378
>emb|CAB86709.1| hypothetical protein L3640.14 [Leishmania major]
          Length = 464

 Score =  228 bits (578), Expect = 2e-58
 Identities = 58/255 (22%), Positives = 93/255 (35%), Gaps = 40/255 (15%)

Query: 159 TVHTDVSAGVPLMLAFADFARRKKYWAKDIIFLVTEQEQLGMQAW--LEAYHGGDEGRIL 216
            V+TD  A V L  A  +  RR+K  A D+ F          + W   +AY         
Sbjct: 88  YVNTDYPASVSLANALIEVIRRRKSLACDVQFYFVNSS----EEWPVPQAY--------- 134

Query: 217 DSGLLRARAGSIQAALNLEVQSLDISHINLKIEGLNGQLPNLDLHNLVQKLSSKNGIIAG 276
                       +AAL L + +L   HI +   G NG  PN D  N+  +L++ N  +  
Sbjct: 135 -----------TRAALVLNLSTLYNRHICIDTLGGNGIQPNQDYTNIAVQLAAANQFLPS 183

Query: 277 YK---QSSSSPKRSFRYQDKLLNLLSMVFSQASGVPTGNHGLFHKYGIEALTLEAVKRER 333
           Y    +  S+      +      L + V  Q    P   H +       ++   A+  + 
Sbjct: 184 YLCQRRHRSTDDAHAGFWHYWAYLEASV--QLPTRPQPWHII----PTHSINTIAISSDP 237

Query: 334 TQQQQ-----FQEVGSMLRIIEGICRSLNNLLERFHQSFFFYLLVSNDRFVSIGDYMPSL 388
                      Q   +  +++  I  SLN L E+FH S F +L VS  R+V        +
Sbjct: 238 LYSASSVFPHSQLPDAFAQLVLKIIVSLNGLEEKFHHSTFVWLPVSLWRYVEYDHAQFCI 297

Query: 389 ALMAGALLIKAFIHY 403
            L   ++    +  Y
Sbjct: 298 ILFVASIFSTTYSEY 312
>ref|NP_491701.1| Putative endoplasmic reticulum membrane protein family member, with
           at least 4 transmembrane domains, nematode specific
           [Caenorhabditis elegans]
 pir||T32772 hypothetical protein F33D11.9a - Caenorhabditis elegans
 gb|AAB96702.1| Hypothetical protein F33D11.9a [Caenorhabditis elegans]
          Length = 229

 Score =  115 bits (288), Expect = 3e-24
 Identities = 19/117 (16%), Positives = 40/117 (33%), Gaps = 15/117 (12%)

Query: 383 DYMPSLALMAGALLIKAFIHYLSLYYTGDNDETEKSEETDAVETKQKAGNIDIGYFSVGI 442
            Y+  L ++   L+I A+  +  +             +         A ++ +G+F    
Sbjct: 1   MYIIPLTILVSPLVISAYFEWTKI-------------QEFQFPVVHLAFHV-LGFFYYIA 46

Query: 443 VLLVAHTLGALVVL-LPQSKAVSNYLHEAELSTQFGLFSLFVAVLVVALTLPAFCSL 498
              V  T+G   VL   Q   V     + + +  + L + F+   ++ L    F   
Sbjct: 47  TTYVFQTIGTTFVLQWMQWPFVGIDGCDGQFTPSWSLINSFLIFFMIPLGPYVFLKT 103
 Score = 84.0 bits (206), Expect = 9e-15
 Identities = 24/107 (22%), Positives = 39/107 (36%), Gaps = 23/107 (21%)

Query: 539 FIILIRPAASR---GAMFLSRLCCL-LINPLVVLYCVLL---ALTWYLFPELAFKPMLN- 590
            I  + P           + R   L ++NP+ VL  V +    +   LFP ++    L  
Sbjct: 88  LIFFMIPLGPYVFLKTRSIFRSSVLAILNPISVLAFVAINIPGMFGQLFPTISQDSWLAA 147

Query: 591 ---KALTATMDALTFSVVDSMIYGNWLFDMVSLIFVPCWVLLWVLLF 634
               ALTA  + + F V          F ++     P    +W +LF
Sbjct: 148 AQSIALTAIREDVEFKVNH--------FFLLCCFGYP----IWNMLF 182
>gb|AAF03176.1|AF110138_8 NADH dehydrogenase subunit 4 [Nephroselmis olivacea]
          Length = 500

 Score = 37.7 bits (87), Expect = 0.88
 Identities = 48/211 (22%), Positives = 89/211 (41%), Gaps = 24/211 (11%)

Query: 439 SVGIVLLVAHTLGALVV-LLPQSKAVSNYLHEAELSTQFGLFSLFVAVLVVA-LTLPAFC 496
           S+ + LL+   LGA +V  LP S     Y+    LS     F   + + +    + P F 
Sbjct: 18  SLLVFLLMFPLLGAALVFFLPFS-----YVRSTALSVSLINFIASLFLWIQFDHSTPQFQ 72

Query: 497 SLSGINGEALHVAVLLELGTVLLAVGMLNFSLGF-SLSVLLVPFIILIRPAASRGAMFLS 555
            ++ I    L ++ L         +G+   SL F  LS  LVP  IL+   + +  +   
Sbjct: 73  FVTKITW--LPISNLHIY------MGIDGISLFFVILSTFLVPICILVGWVSIQTYVREY 124

Query: 556 RLCCLLI-NPLVVLYCVLLALTWYLFPELAFKPMLNKALTATMDALTFSVVDSMIYGNWL 614
            +  L++ + ++ ++C+L  L +Y+F E    PM             +   +  I   + 
Sbjct: 125 VIAFLILESCMIAVFCMLDLLLFYVFFESVLIPMFLII-------GIWGSRERKIRAAYQ 177

Query: 615 FDMVSLIFVPCWVLLWVLLFPKTATNDRQTV 645
           F + +L      +L  +L++ +T T D Q +
Sbjct: 178 FFLYTLFGSVLMLLAIILIYFQTGTTDLQVL 208
>sp|P30803|CYA5_CANFA Adenylate cyclase, type V (ATP pyrophosphate-lyase)
           (Ca(2+)-inhibitable adenylyl cyclase)
 gb|AAC32726.1| adenylyl cyclase type V [Canis familiaris]
          Length = 1265

 Score = 36.5 bits (84), Expect = 2.4
 Identities = 34/174 (19%), Positives = 67/174 (37%), Gaps = 21/174 (12%)

Query: 342 VGSMLRIIEGICRSL---NNLLERFHQSFFFYL---LVSNDRFVSIGDYMPSLALMAGAL 395
            G+  R +  I RS    ++ LER +Q +FF L    ++    V +   +  LA  A   
Sbjct: 208 PGACCRALLQIFRSKKFPSDKLERLYQRYFFRLNQSSLTMLMAVLVLVCLVMLAFHAARP 267

Query: 396 LIKAFIHYLSLYYTGDNDETEKSEETDAVETKQKAGNIDIGYFSVGIVLLVAHTLGALVV 455
            ++     +     G            A        ++ +  +++  V+L    +G    
Sbjct: 268 PLRLPHLAVLAAAVGVILVMAVLCNRAAFH----QDHMGLACYALIAVVLAVQVVGL--- 320

Query: 456 LLPQSKAVSNYLHEAELSTQFGLFSLFVAVLVVALTLPAFCSLSGINGEALHVA 509
           LLPQ ++       A     + +F ++    ++ + +     LSG+   ALH+A
Sbjct: 321 LLPQPRS-------ASEGIWWTVFFIYTIYTLLPVRM-RAAVLSGVLLSALHLA 366
CPU time:   212.22 user secs.	    3.31 sys. secs	  215.53 total secs.

  Database: nr
    Posted date:  Jan 18, 2003  1:23 PM
  Number of letters in database: 421,297,171
  Number of sequences in database:  1,315,992
  
Lambda     K      H
   0.315    0.173    0.466 

Gapped
Lambda     K      H
   0.270   0.0606    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 588276107
Number of Sequences: 1315992
Number of extensions: 27447555
Number of successful extensions: 87371
Number of sequences better than 10.0: 374
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 351
Number of HSP's that attempted gapping in prelim test: 87033
Number of HSP's gapped (non-prelim): 480
length of query: 647
length of database: 421,297,171
effective HSP length: 58
effective length of query: 589
effective length of database: 344,969,635
effective search space: 203187115015
effective search space used: 203187115015
T: 11
A: 40
X1: 15 ( 6.8 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.2 bits)
S2: 78 (34.4 bits)