BLAST Search Results

BLASTP 2.1.1 [Aug-8-2000]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 
         (300 letters)

Database: nr
           598,029 sequences; 189,012,571 total letters

Searching..................................................

E-value threshold for inclusion in PSI-Blast iteration 4: 0.002 
E-value threshold for inclusion in PSI-Blast iteration 5: 




 Results of PSI-Blast iteration 3

Distribution of 50 Blast Hits on the Query Sequence


Legend:
 - means that the alignment score was below the threshold on the previous iteration 
 - means that the alignment was checked on the previous iteration 
Sequences with E-value BETTER than threshold 

                                                                     Score    E
Sequences producing significant alignments:                          (bits) Value


 ref|NP_055601.1|  KIAA0337 gene product [Homo sapiens] >gi|222461...   466  e-130

 gb|AAF55465.1|  (AE003719) CG7397 gene product [Drosophila melano...   378  e-104

 ref|XP_006365.1|  KIAA0337 gene product [Homo sapiens]                 328  4e-89

 ref|NP_067585.1|  breakpoint cluster region, isoform 2 [Homo sapi...   285  4e-76

 gb|AAB60390.1|  (U07000) breakpoint cluster region protein [Homo ...   284  6e-76

 gb|AAB60389.1|  (U07000) breakpoint cluster region protein [Homo ...   284  6e-76

 ref|XP_009870.1|  breakpoint cluster region, isoform 1 [Homo sapi...   284  6e-76

 prf||1107276A  gene bcr [Homo sapiens]                                 282  2e-75

 ref|NP_004318.2|  breakpoint cluster region, isoform 1 [Homo sapi...   282  2e-75

 gb|AAA65939.1|  (M24603) bcr [Homo sapiens]                            245  6e-64

 ref|XP_008545.1|  active BCR-related gene [Homo sapiens]               226  3e-58

 pir||B47485  ABR protein 2 - human                                     226  3e-58

 ref|NP_068781.1|  active breakpoint cluster region-related  prote...   226  3e-58

 ref|NP_001083.1|  active breakpoint cluster region-related  prote...   226  3e-58

 gb|AAA88013.1|  (M30829) bcr/abl fusion protein [Homo sapiens]         224  1e-57

 prf||1107272B  abl gene [Homo sapiens]                                 224  1e-57

 emb|CAA21413.1|  (AL031884) /prediction=(method:""genefinder"", v...   196  2e-49

 gb|AAF45386.1|  (AE002567) EG:23E12.2 gene product [Drosophila me...   194  8e-49

 sp|Q21653|YNG2_CAEEL  HYPOTHETICAL 54.3 KD PROTEIN R02F2.2 IN CHR...   175  6e-43

 gb|AAA87612.1|  (M30832) bcr/abl fusion protein [Homo sapiens]         155  6e-37

 emb|CAA10376.1|  (AJ131466) BCR/ABL (major breakpoint) fusion pep...   140  2e-32

 emb|CAA10377.1|  (AJ131467) BCR/ABL chimeric fusion peptide [Homo...   128  9e-29

 gb|AAF61858.1|  (AF192533) BCR-ABL fusion protein [Homo sapiens]        59  7e-08


Sequences with E-value WORSE than threshold 

 ref|XP_005166.1|  KIAA0294 gene product [Homo sapiens]                  41  0.016

 ref|NP_055444.1|  Rho guanine nucleotide exchange factor (GEF) 10...    41  0.016

 dbj|BAB13452.1|  (AB046846) KIAA1626 protein [Homo sapiens]             40  0.037

 pir||T03307  hypothetical protein AAB71662.1 - human (fragment) >...    40  0.037

 dbj|BAB12119.1|  (AB047595) hypothetical protein [Macaca fascicul...    39  0.063

 dbj|BAA92600.1|  (AB037783) KIAA1362 protein [Homo sapiens]             38  0.11

 ref|NP_060821.1|  hypothetical protein FLJ11183 [Homo sapiens] >g...    38  0.11

 dbj|BAA83062.1|  (AB029033) KIAA1110 protein [Homo sapiens]             38  0.11

 dbj|BAA97653.1|  (AB018223) acetylspermidine oxidase [Candida boi...    38  0.14

 ref|XP_007065.1|  FERM, RhoGEF, and pleckstrin domain protein 1 [...    38  0.19

 pir||JC5795  CDEP protein - human                                       38  0.19

 ref|NP_005757.1|  FERM, RhoGEF, and pleckstrin domain protein 1; ...    38  0.19

 ref|XP_005638.1|  vav 2 oncogene [Homo sapiens]                         36  0.42

 pir||A59235  unconventional myosin heavy chain MyoM - slime mold ...    36  0.42

 ref|NP_033526.1|  Vav2 oncogene [Mus musculus] >gi|2494862|sp|Q60...    36  0.42

 sp|Q55750|MFD_SYNY3  TRANSCRIPTION-REPAIR COUPLING FACTOR (TRCF) ...    36  0.42

 ref|NP_003362.1|  vav 2 oncogene; Oncogene VAV2 [Homo sapiens] >g...    36  0.42

 ref|XP_007501.1|  hypothetical protein FLJ10357 [Homo sapiens]          35  0.94

 ref|XP_002741.1|  KIAA0793 gene product [Homo sapiens]                  35  0.94

 dbj|BAB15753.1|  (AK024463) FLJ00056 protein [Homo sapiens]             35  0.94

 ref|NP_060541.1|  hypothetical protein FLJ10357 [Homo sapiens] >g...    35  0.94

 pir||T46359  hypothetical protein DKFZp434K1316.1 - human (fragme...    35  0.94

 ref|NP_055623.1|  KIAA0793 gene product [Homo sapiens] >gi|388230...    35  0.94

 dbj|BAA31629.1|  (AB014554) KIAA0654 protein [Homo sapiens]             35  0.94

 ref|XP_001623.1|  hypothetical protein FLJ10521 [Homo sapiens]          35  1.2

 dbj|BAA92629.1|  (AB037812) KIAA1391 protein [Homo sapiens]             35  1.2

 ref|NP_060595.1|  hypothetical protein FLJ10521 [Homo sapiens] >g...    35  1.2


Alignments
>ref|NP_055601.1| KIAA0337 gene product [Homo sapiens]
 dbj|BAA20795.1| (AB002335) KIAA0337 [Homo sapiens]
          Length = 1510

 Score =  466 bits (1186), Expect = e-130
 Identities = 300/300 (100%), Positives = 300/300 (100%)

Query: 1    GVRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTD 60
            GVRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTD
Sbjct: 701  GVRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTD 760

Query: 61   LIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENI 120
            LIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENI
Sbjct: 761  LIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENI 820

Query: 121  QKAISRLDEDLTTLGQMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPP 180
            QKAISRLDEDLTTLGQMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPP
Sbjct: 821  QKAISRLDEDLTTLGQMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPP 880

Query: 181  TKLELCATRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKT 240
            TKLELCATRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKT
Sbjct: 881  TKLELCATRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKT 940

Query: 241  RSGMQFSCAAPTLNSCPEPSPEVWVCNSDGYVGQVCLLSLRAEPDVEACIAVCSARILCI 300
            RSGMQFSCAAPTLNSCPEPSPEVWVCNSDGYVGQVCLLSLRAEPDVEACIAVCSARILCI
Sbjct: 941  RSGMQFSCAAPTLNSCPEPSPEVWVCNSDGYVGQVCLLSLRAEPDVEACIAVCSARILCI 1000



>gb|AAF55465.1| (AE003719) CG7397 gene product [Drosophila melanogaster]
          Length = 1101

 Score =  378 bits (961), Expect = e-104
 Identities = 127/298 (42%), Positives = 189/298 (62%), Gaps = 15/298 (5%)

Query: 6   EEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCT 65
           E  +R A  L+E+E  IEG+ DL AP R+FL  ++V      G +KDR  FLF DL+V T
Sbjct: 348 ENGQREA-TLRELEGVIEGITDLIAPERQFLLFDLVSMPSGQGARKDRGFFLFNDLLVLT 406

Query: 66  TLKRKSGSLRRSSMSLY--TAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKA 123
           ++K++SG++R+ + S+   T A+ +DT +KYK L K+ L+  +I+K  S+  N + I   
Sbjct: 407 SIKKRSGTIRKPNSSICPGTVATTLDT-NKYKFLTKISLDCLEIVK--SKDENIKRIVSE 463

Query: 124 ISRLDEDLTTLGQMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKL 183
           I  L ED   L Q++ ++ ++ +PHQ L+D +R+L   + R LSE+Q     L+     L
Sbjct: 464 IETLAEDCNKLQQITDITVTIKYPHQYLEDVIRELHREVQRQLSERQTNDTQLNM----L 519

Query: 184 ELCATRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLD-PEFLKAIPIMKTRS 242
           EL  + P G       F   + R  +E++F+EAK+KLA++      PEFL +IPI KTR+
Sbjct: 520 ELTVSSPNGNQKLAVVFSKTEKRTQWEESFNEAKQKLAATLERHPIPEFLTSIPIRKTRA 579

Query: 243 GMQFSCAAPTLNSCPEPSPEVWVCNSDGYVGQVCLLSLRAEPDVEACIAVCSARILCI 300
           G+QF+CAA TL+     + +VWVCNSDGYVGQVC++SL  EP+V +C  VC+ARILC+
Sbjct: 580 GLQFTCAAATLSD----NRDVWVCNSDGYVGQVCIMSLHPEPNVTSCNGVCNARILCV 633



>ref|XP_006365.1| KIAA0337 gene product [Homo sapiens]
          Length = 726

 Score =  328 bits (833), Expect = 4e-89
 Identities = 221/223 (99%), Positives = 221/223 (99%)

Query: 25  MEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTA 84
           MEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTA
Sbjct: 1   MEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTA 60

Query: 85  ASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLGQMSKLSESL 144
           ASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLGQMSKLSESL
Sbjct: 61  ASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLGQMSKLSESL 120

Query: 145 GFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDSYIFEFPHPD 204
           GFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDSYIFEFPHPD
Sbjct: 121 GFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDSYIFEFPHPD 180

Query: 205 ARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFS 247
           ARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQ  
Sbjct: 181 ARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQVC 223



>ref|NP_067585.1| breakpoint cluster region, isoform 2 [Homo sapiens]
 emb|CAA68676.1| (Y00661) bcr polypeptide [Homo sapiens]
          Length = 1227

 Score =  285 bits (722), Expect = 4e-76
 Identities = 54/252 (21%), Positives = 95/252 (37%), Gaps = 36/252 (14%)

Query: 17  EIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRR 76
           EI    + M   +   R+ L+   ++E+   G +K R +FLFTDL++CT LK++SG    
Sbjct: 691 EITPRRQSMTVKKGEHRQLLKDSFMVEL-VEGARKLRHVFLFTDLLLCTKLKKQSG---- 745

Query: 77  SSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLG- 135
                           +Y   W +PL D    +   +     NI       DE+L  L  
Sbjct: 746 ------------GKTQQYDCKWYIPLTDLS-FQMVDELEAVPNIPL---VPDEELDALKI 789

Query: 136 QMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDS 195
           ++S++   +    +   +     +  + + LSE+++L   L      +        G  S
Sbjct: 790 KISQIKSDIQ--REKRANKGSKATERLKKKLSEQESL---LLLMSPSMAFRVHSRNG-KS 843

Query: 196 YIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTL-- 253
           Y F       R  + +   E ++K   S S    E       M T S ++          
Sbjct: 844 YTFLISSDYERAEWRENIREQQKKCFRSFSLTSVEL-----QMLTNSCVKLQTVHSIPLT 898

Query: 254 -NSCPEPSPEVW 264
            N   + SP ++
Sbjct: 899 INKEDDESPGLY 910



>gb|AAB60390.1| (U07000) breakpoint cluster region protein [Homo sapiens]
          Length = 936

 Score =  284 bits (720), Expect = 6e-76
 Identities = 54/252 (21%), Positives = 95/252 (37%), Gaps = 36/252 (14%)

Query: 17  EIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRR 76
           EI    + M   +   R+ L+   ++E+   G +K R +FLFTDL++CT LK++SG    
Sbjct: 356 EITPRRQSMTVKKGEHRQLLKDSFMVEL-VEGARKLRHVFLFTDLLLCTKLKKQSG---- 410

Query: 77  SSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLG- 135
                           +Y   W +PL D    +   +     NI       DE+L  L  
Sbjct: 411 ------------GKTQQYDCKWYIPLTDLS-FQMVDELEAVPNIPL---VPDEELDALKI 454

Query: 136 QMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDS 195
           ++S++   +    +   +     +  + + LSE+++L   L      +        G  S
Sbjct: 455 KISQIKNDIQ--REKRANKGSKATERLKKKLSEQESL---LLLMSPSMAFRVHSRNG-KS 508

Query: 196 YIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTL-- 253
           Y F       R  + +   E ++K   S S    E       M T S ++          
Sbjct: 509 YTFLISSDYERAEWRENIREQQKKCFRSFSLTSVEL-----QMLTNSCVKLQTVHSIPLT 563

Query: 254 -NSCPEPSPEVW 264
            N   + SP ++
Sbjct: 564 INKEDDESPGLY 575



>gb|AAB60389.1| (U07000) breakpoint cluster region protein [Homo sapiens]
          Length = 889

 Score =  284 bits (720), Expect = 6e-76
 Identities = 54/252 (21%), Positives = 95/252 (37%), Gaps = 36/252 (14%)

Query: 17  EIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRR 76
           EI    + M   +   R+ L+   ++E+   G +K R +FLFTDL++CT LK++SG    
Sbjct: 309 EITPRRQSMTVKKGEHRQLLKDSFMVEL-VEGARKLRHVFLFTDLLLCTKLKKQSG---- 363

Query: 77  SSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLG- 135
                           +Y   W +PL D    +   +     NI       DE+L  L  
Sbjct: 364 ------------GKTQQYDCKWYIPLTDLS-FQMVDELEAVPNIPL---VPDEELDALKI 407

Query: 136 QMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDS 195
           ++S++   +    +   +     +  + + LSE+++L   L      +        G  S
Sbjct: 408 KISQIKNDIQ--REKRANKGSKATERLKKKLSEQESL---LLLMSPSMAFRVHSRNG-KS 461

Query: 196 YIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTL-- 253
           Y F       R  + +   E ++K   S S    E       M T S ++          
Sbjct: 462 YTFLISSDYERAEWRENIREQQKKCFRSFSLTSVEL-----QMLTNSCVKLQTVHSIPLT 516

Query: 254 -NSCPEPSPEVW 264
            N   + SP ++
Sbjct: 517 INKEDDESPGLY 528



>ref|XP_009870.1| breakpoint cluster region, isoform 1 [Homo sapiens]
 gb|AAB60388.1| (U07000) breakpoint cluster region protein [Homo sapiens]
          Length = 1271

 Score =  284 bits (720), Expect = 6e-76
 Identities = 54/252 (21%), Positives = 95/252 (37%), Gaps = 36/252 (14%)

Query: 17  EIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRR 76
           EI    + M   +   R+ L+   ++E+   G +K R +FLFTDL++CT LK++SG    
Sbjct: 691 EITPRRQSMTVKKGEHRQLLKDSFMVEL-VEGARKLRHVFLFTDLLLCTKLKKQSG---- 745

Query: 77  SSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLG- 135
                           +Y   W +PL D    +   +     NI       DE+L  L  
Sbjct: 746 ------------GKTQQYDCKWYIPLTDLS-FQMVDELEAVPNIPL---VPDEELDALKI 789

Query: 136 QMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDS 195
           ++S++   +    +   +     +  + + LSE+++L   L      +        G  S
Sbjct: 790 KISQIKNDIQ--REKRANKGSKATERLKKKLSEQESL---LLLMSPSMAFRVHSRNG-KS 843

Query: 196 YIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTL-- 253
           Y F       R  + +   E ++K   S S    E       M T S ++          
Sbjct: 844 YTFLISSDYERAEWRENIREQQKKCFRSFSLTSVEL-----QMLTNSCVKLQTVHSIPLT 898

Query: 254 -NSCPEPSPEVW 264
            N   + SP ++
Sbjct: 899 INKEDDESPGLY 910



>prf||1107276A gene bcr [Homo sapiens]
          Length = 589

 Score =  282 bits (715), Expect = 2e-75
 Identities = 53/252 (21%), Positives = 95/252 (37%), Gaps = 36/252 (14%)

Query: 17  EIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRR 76
           EI    + M   +   R+ L+   ++E+   G +K R +FLFT+L++CT LK++SG    
Sbjct: 9   EITPRRQSMTVKKGEHRQLLKDSFMVEL-VEGARKLRHVFLFTELLLCTKLKKQSG---- 63

Query: 77  SSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLG- 135
                           +Y   W +PL D    +   +     NI       DE+L  L  
Sbjct: 64  ------------GKTQQYDCKWYIPLTDLS-FQMVDELEAVPNIPL---VPDEELDALKI 107

Query: 136 QMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDS 195
           ++S++   +    +   +     +  + + LSE+++L   L      +        G  S
Sbjct: 108 KISQIKSDIQ--REKRANKGSKATERLKKKLSEQESL---LLLMSPSMAFRVHSRNG-KS 161

Query: 196 YIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTL-- 253
           Y F       R  + +   E ++K   S S    E       M T S ++          
Sbjct: 162 YTFLISSDYERAEWRENIREQQKKCFRSFSLTSVEL-----QMLTNSCVKLQTVHSIPLT 216

Query: 254 -NSCPEPSPEVW 264
            N   + SP ++
Sbjct: 217 INKEDDESPGLY 228



>ref|NP_004318.2| breakpoint cluster region, isoform 1 [Homo sapiens]
 sp|P11274|BCR_HUMAN BREAKPOINT CLUSTER REGION PROTEIN
 pir||TVHUBR bcr (breakpoint cluster region) protein, splice form 1 - human
 emb|CAA26441.1| (X02596) bcr [Homo sapiens]
          Length = 1271

 Score =  282 bits (715), Expect = 2e-75
 Identities = 53/252 (21%), Positives = 95/252 (37%), Gaps = 36/252 (14%)

Query: 17  EIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRR 76
           EI    + M   +   R+ L+   ++E+   G +K R +FLFT+L++CT LK++SG    
Sbjct: 691 EITPRRQSMTVKKGEHRQLLKDSFMVEL-VEGARKLRHVFLFTELLLCTKLKKQSG---- 745

Query: 77  SSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLG- 135
                           +Y   W +PL D    +   +     NI       DE+L  L  
Sbjct: 746 ------------GKTQQYDCKWYIPLTDLS-FQMVDELEAVPNIPL---VPDEELDALKI 789

Query: 136 QMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDS 195
           ++S++   +    +   +     +  + + LSE+++L   L      +        G  S
Sbjct: 790 KISQIKSDIQ--REKRANKGSKATERLKKKLSEQESL---LLLMSPSMAFRVHSRNG-KS 843

Query: 196 YIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTL-- 253
           Y F       R  + +   E ++K   S S    E       M T S ++          
Sbjct: 844 YTFLISSDYERAEWRENIREQQKKCFRSFSLTSVEL-----QMLTNSCVKLQTVHSIPLT 898

Query: 254 -NSCPEPSPEVW 264
            N   + SP ++
Sbjct: 899 INKEDDESPGLY 910



>gb|AAA65939.1| (M24603) bcr [Homo sapiens]
          Length = 872

 Score =  245 bits (618), Expect = 6e-64
 Identities = 45/209 (21%), Positives = 82/209 (38%), Gaps = 28/209 (13%)

Query: 17  EIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRR 76
           EI    + M   +   R+ L+   ++E+   G +K R +FLFT+L++CT LK++SG    
Sbjct: 691 EITPRRQSMTVKKGEHRQLLKDSFMVEL-VEGARKLRHVFLFTELLLCTKLKKQSG---- 745

Query: 77  SSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLG- 135
                           +Y   W +PL D    +   +     NI       DE+L  L  
Sbjct: 746 ------------GKTQQYDCKWYIPLTDLS-FQMVDELEAVPNIPL---VPDEELDALKI 789

Query: 136 QMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDS 195
           ++S++   +    +   +     +  + + LSE+++L   L      +        G  S
Sbjct: 790 KISQIKSDIQ--REKRANKGSKATERLKKKLSEQESL---LLLMSPSMAFRVHSRNG-KS 843

Query: 196 YIFEFPHPDARLGFEQAFDEAKRKLASSK 224
           Y F       R  + +   E ++K   S 
Sbjct: 844 YTFLISSDYERAEWRENIREQQKKCFRSF 872



>ref|XP_008545.1| active BCR-related gene [Homo sapiens]
          Length = 663

 Score =  226 bits (569), Expect = 3e-58
 Identities = 40/252 (15%), Positives = 85/252 (32%), Gaps = 36/252 (14%)

Query: 17  EIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRR 76
           +I+     +   +   R+ ++   ++EV     +K R +FLFTD+++C  LK+ S     
Sbjct: 247 DIDPRRTAVTTPKGETRQLVKDGFLVEVS-ESSRKLRHVFLFTDVLLCAKLKKTSA---- 301

Query: 77  SSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLG- 135
                           +Y   W +PL D  +     ++     +       D +L  +  
Sbjct: 302 ------------GKHQQYDCKWYIPLADL-VFPSPEESEASPQVH---PFPDHELEDMKM 345

Query: 136 QMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDS 195
           ++S L   +    +  +         + + + E + L   L      +        G  S
Sbjct: 346 KISALKSEIQ--KEKANKGQSRAIERLKKKMFENEFL---LLLNSPTIPFRIHNRNG-KS 399

Query: 196 YIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTL-- 253
           Y+F       R  + +A  + ++K   +      E       + T S  +          
Sbjct: 400 YLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVEL-----QVLTGSCFKLRTVHNIPVT 454

Query: 254 -NSCPEPSPEVW 264
            N   + SP ++
Sbjct: 455 SNKDDDESPGLY 466



>pir||B47485 ABR protein 2 - human
          Length = 813

 Score =  226 bits (569), Expect = 3e-58
 Identities = 40/252 (15%), Positives = 85/252 (32%), Gaps = 36/252 (14%)

Query: 17  EIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRR 76
           +I+     +   +   R+ ++   ++EV     +K R +FLFTD+++C  LK+ S     
Sbjct: 238 DIDPRRTAVTTPKGETRQLVKDGFLVEVS-ESSRKLRHVFLFTDVLLCAKLKKTSA---- 292

Query: 77  SSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLG- 135
                           +Y   W +PL D  +     ++     +       D +L  +  
Sbjct: 293 ------------GKHQQYDCKWYIPLADL-VFPSPEESEASPQVH---PFPDHELEDMKM 336

Query: 136 QMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDS 195
           ++S L   +    +  +         + + + E + L   L      +        G  S
Sbjct: 337 KISALKSEIQ--KEKANKGQSRAIERLKKKMFENEFL---LLLNSPTIPFRIHNRNG-KS 390

Query: 196 YIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTL-- 253
           Y+F       R  + +A  + ++K   +      E       + T S  +          
Sbjct: 391 YLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVEL-----QVLTGSCFKLRTVHNIPVT 445

Query: 254 -NSCPEPSPEVW 264
            N   + SP ++
Sbjct: 446 SNKDDDESPGLY 457



>ref|NP_068781.1| active breakpoint cluster region-related  protein, isoform a [Homo
           sapiens]
 sp|Q12979|ABR_HUMAN ACTIVE BREAKPOINT CLUSTER REGION-RELATED PROTEIN
 pir||A49307 98K GTPase-activating protein ABR, brain - human
 gb|AAC50063.1| (U01147) guanine nucleotide regulatory protein [Homo sapiens]
          Length = 859

 Score =  226 bits (569), Expect = 3e-58
 Identities = 40/252 (15%), Positives = 85/252 (32%), Gaps = 36/252 (14%)

Query: 17  EIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRR 76
           +I+     +   +   R+ ++   ++EV     +K R +FLFTD+++C  LK+ S     
Sbjct: 284 DIDPRRTAVTTPKGETRQLVKDGFLVEVS-ESSRKLRHVFLFTDVLLCAKLKKTSA---- 338

Query: 77  SSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLG- 135
                           +Y   W +PL D  +     ++     +       D +L  +  
Sbjct: 339 ------------GKHQQYDCKWYIPLADL-VFPSPEESEASPQVH---PFPDHELEDMKM 382

Query: 136 QMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDS 195
           ++S L   +    +  +         + + + E + L   L      +        G  S
Sbjct: 383 KISALKSEIQ--KEKANKGQSRAIERLKKKMFENEFL---LLLNSPTIPFRIHNRNG-KS 436

Query: 196 YIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTL-- 253
           Y+F       R  + +A  + ++K   +      E       + T S  +          
Sbjct: 437 YLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVEL-----QVLTGSCFKLRTVHNIPVT 491

Query: 254 -NSCPEPSPEVW 264
            N   + SP ++
Sbjct: 492 SNKDDDESPGLY 503



>ref|NP_001083.1| active breakpoint cluster region-related  protein, isoform b [Homo
           sapiens]
 pir||A47485 ABR protein 1 - human
 gb|AAC37519.1| (L19704) alternative first exon [Homo sapiens]
          Length = 822

 Score =  226 bits (569), Expect = 3e-58
 Identities = 40/252 (15%), Positives = 85/252 (32%), Gaps = 36/252 (14%)

Query: 17  EIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRR 76
           +I+     +   +   R+ ++   ++EV     +K R +FLFTD+++C  LK+ S     
Sbjct: 247 DIDPRRTAVTTPKGETRQLVKDGFLVEVS-ESSRKLRHVFLFTDVLLCAKLKKTSA---- 301

Query: 77  SSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLG- 135
                           +Y   W +PL D  +     ++     +       D +L  +  
Sbjct: 302 ------------GKHQQYDCKWYIPLADL-VFPSPEESEASPQVH---PFPDHELEDMKM 345

Query: 136 QMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDS 195
           ++S L   +    +  +         + + + E + L   L      +        G  S
Sbjct: 346 KISALKSEIQ--KEKANKGQSRAIERLKKKMFENEFL---LLLNSPTIPFRIHNRNG-KS 399

Query: 196 YIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTL-- 253
           Y+F       R  + +A  + ++K   +      E       + T S  +          
Sbjct: 400 YLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVEL-----QVLTGSCFKLRTVHNIPVT 454

Query: 254 -NSCPEPSPEVW 264
            N   + SP ++
Sbjct: 455 SNKDDDESPGLY 466



>gb|AAA88013.1| (M30829) bcr/abl fusion protein [Homo sapiens]
          Length = 284

 Score =  224 bits (564), Expect = 1e-57
 Identities = 41/210 (19%), Positives = 74/210 (34%), Gaps = 35/210 (16%)

Query: 59  TDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRE 118
           TDL++CT LK++SG                    +Y   W +P+ D    +   +     
Sbjct: 1   TDLLLCTKLKKQSG----------------GKTQQYDCKWYIPVTDLS-FQMVDELEAVP 43

Query: 119 NIQKAISRLDEDLTTLG-QMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALS 177
           NI       DE+L  L  ++S++   +    +   +     +  + + LSE+++L   L 
Sbjct: 44  NIPL---VPDEELNALKIKISQIKSDIQ--REKRANKGSKATERLKKKLSEQESL---LL 95

Query: 178 FPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPI 237
                +        G  SY F       R  + +   E ++K   S S    E       
Sbjct: 96  LMSPSMAFRVHSRNG-KSYTFLISSDYERAEWRENIREQQKKCFRSFSLASVEL-----Q 149

Query: 238 MKTRSGMQFSCAAPTL---NSCPEPSPEVW 264
           M T S ++           N   + SP ++
Sbjct: 150 MLTNSCVKLQTVHSIPLTINKEDDESPGLY 179



>prf||1107272B abl gene [Homo sapiens]
          Length = 285

 Score =  224 bits (564), Expect = 1e-57
 Identities = 42/210 (20%), Positives = 74/210 (35%), Gaps = 35/210 (16%)

Query: 59  TDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRE 118
           TDL++CT LK++SG                    +Y   W +PL D    +   +     
Sbjct: 1   TDLLLCTKLKKQSG----------------GKTQQYDCKWYIPLTDLS-FQMVDELEAVP 43

Query: 119 NIQKAISRLDEDLTTLG-QMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALS 177
           NI       DE+L  L  ++S++   +    +   +     +  + + LSE+++L   L 
Sbjct: 44  NIPL---VPDEELNALKIKISQIKSDIQ--REKRANKGSKATERLKKKLSEQESL---LL 95

Query: 178 FPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPI 237
                +        G  SY F       R  + +   E ++K   S S    E       
Sbjct: 96  LMSPSMAFRVHSRNG-KSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVEL-----Q 149

Query: 238 MKTRSGMQFSCAAPTL---NSCPEPSPEVW 264
           M T S ++           N   + SP ++
Sbjct: 150 MLTNSCVKLQTVHSIPLTINKEDDESPGLY 179



>emb|CAA21413.1| (AL031884) /prediction=(method:""genefinder"",
           version:""084"")~/prediction=(method:""genscan"",
           version:""1.0"")~/match=(desc:""BREAKPOINT CLUSTER
           REGION PROTEIN"", species:""HOMO SAPIENS (HUMAN)"",
           ranges:(query:22532..22813, target:SWISS-PROT::P1127>
          Length = 658

 Score =  196 bits (494), Expect = 2e-49
 Identities = 50/263 (19%), Positives = 87/263 (33%), Gaps = 34/263 (12%)

Query: 32  LRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTA 91
           LRR +R   ++E+   G +K R LFLF D+I C   K                A   D  
Sbjct: 178 LRRMVRNSFIVEL-VDGHRKLRHLFLFNDVIACAKYK----------------ALGRDRI 220

Query: 92  SKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLGQMSKLSESLGFPHQSL 151
             Y++ W +PL+D  I + A        ++   S           +  + + L     + 
Sbjct: 221 D-YELKWFIPLKDVSIYEEAD-----PAVELKESSPANISQVKRNLRSVRDQLAMEVANS 274

Query: 152 DDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQ 211
                       R L++ ++    L      L L         +  F       R  +  
Sbjct: 275 GSGGFRSGDKYRRKLADLES---QLVLATPNLVLRLGNKANNKTITFFLSSDFERTQWID 331

Query: 212 AFDEAKRKL--ASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTLNSCPEPSPEVWVCNSD 269
           +    K+K     + +    E    I  M+   GM+    +  + +  + S    +   D
Sbjct: 332 SILSLKQKCNLPGANTINSLEVTAFIVAMQ--KGMKTEMGSYLMRNTNDES----LLVGD 385

Query: 270 GYVGQVCLLSLRAEPDVEACIAV 292
            Y+G   L  L    D+  C+ V
Sbjct: 386 LYMGVHGLEGLEQANDLYICVEV 408



>gb|AAF45386.1| (AE002567) EG:23E12.2 gene product [Drosophila melanogaster]
          Length = 718

 Score =  194 bits (489), Expect = 8e-49
 Identities = 50/263 (19%), Positives = 87/263 (33%), Gaps = 34/263 (12%)

Query: 32  LRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTA 91
           LRR +R   ++E+   G +K R LFLF D+I C   K                A   D  
Sbjct: 178 LRRMVRNSFIVEL-VDGHRKLRHLFLFNDVIACAKYK----------------ALGRDRI 220

Query: 92  SKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLGQMSKLSESLGFPHQSL 151
             Y++ W +PL+D  I + A        ++   S           +  + + L     + 
Sbjct: 221 D-YELKWFIPLKDVSIYEEAD-----PAVELKESSPANISQVKRNLRSVRDQLAMEVANS 274

Query: 152 DDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQ 211
                       R L++ ++    L      L L         +  F       R  +  
Sbjct: 275 GSGAFRSGDKYRRKLADLES---QLVLATPNLVLRLGNKANNKTITFFLSSDFERTQWID 331

Query: 212 AFDEAKRKL--ASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTLNSCPEPSPEVWVCNSD 269
           +    K+K     + +    E    I  M+   GM+    +  + +  + S    +   D
Sbjct: 332 SILSLKQKCNLPGANTINSLEVTAFIVAMQ--KGMKTEMGSYLMRNTNDES----LLVGD 385

Query: 270 GYVGQVCLLSLRAEPDVEACIAV 292
            Y+G   L  L    D+  C+ V
Sbjct: 386 LYMGVHGLEGLEQANDLYICVEV 408



>sp|Q21653|YNG2_CAEEL HYPOTHETICAL 54.3 KD PROTEIN R02F2.2 IN CHROMOSOME III
 pir||T16659 hypothetical protein R02F2.2 - Caenorhabditis elegans
 gb|AAA50719.1| (U00055) R02F2.2 gene product [Caenorhabditis elegans]
          Length = 492

 Score =  175 bits (439), Expect = 6e-43
 Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 5/135 (3%)

Query: 164 RDLSEKQALCYALSFPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASS 223
           R+L+E+ +    LS     + L      G + ++ EFP+ + R  FE  F +AK  LA +
Sbjct: 14  RELNEQMSSDPDLS----AVHLDVLTSNGFEPFVLEFPNAEKRSVFEAMFKDAKATLAKN 69

Query: 224 KSCLDPEFLKAIPIMKTRSGMQFSCAAPTLNSCPEPSPEVWVCNSDGYVGQVCLLSL-RA 282
                   LK I   +TR G+Q   A        + +P +WVC SD + GQV +++L   
Sbjct: 70  LLAAPSCSLKTIIAHQTRPGLQLCTATVVPGKRVDSTPSLWVCASDKFSGQVAVMALDTG 129

Query: 283 EPDVEACIAVCSARI 297
           E  +E+C A+ +A +
Sbjct: 130 EITIESCSAIGNAAV 144



>gb|AAA87612.1| (M30832) bcr/abl fusion protein [Homo sapiens]
          Length = 225

 Score =  155 bits (388), Expect = 6e-37
 Identities = 22/131 (16%), Positives = 44/131 (32%), Gaps = 14/131 (10%)

Query: 137 MSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDSY 196
           +S++   +    +   +     +  + + LSE+++L   L      +        G  SY
Sbjct: 1   ISQIKSDIQ--REKRANKGSKATERLKKKLSEQESL---LLLMSPSMAFRVHSRNG-KSY 54

Query: 197 IFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTL--- 253
            F       R  + +   E ++K   S S    E       M T S ++           
Sbjct: 55  TFLISSDYERAEWRENIREQQKKCFRSFSLASVEL-----QMLTNSCVKLQTVHSIPLTI 109

Query: 254 NSCPEPSPEVW 264
           N   + SP ++
Sbjct: 110 NKEDDESPGLY 120



>emb|CAA10376.1| (AJ131466) BCR/ABL (major breakpoint) fusion peptide [Homo sapiens]
          Length = 332

 Score =  140 bits (349), Expect = 2e-32
 Identities = 21/116 (18%), Positives = 38/116 (32%), Gaps = 12/116 (10%)

Query: 152 DDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQ 211
            +     +  + + LSE+++L   L      +        G  SY F       R  + +
Sbjct: 1   ANKGSKATERLKKKLSEQESL---LLLMSPSMAFRVHSRNG-KSYTFLISSDYERAEWRE 56

Query: 212 AFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTL---NSCPEPSPEVW 264
              E ++K   S S    E       M T S ++           N   + SP ++
Sbjct: 57  NIREQQKKCFRSFSLTSVEL-----QMLTNSCVKLQTVHSIPLTINKEDDESPGLY 107



>emb|CAA10377.1| (AJ131467) BCR/ABL chimeric fusion peptide [Homo sapiens]
          Length = 307

 Score =  128 bits (318), Expect = 9e-29
 Identities = 18/102 (17%), Positives = 32/102 (30%), Gaps = 9/102 (8%)

Query: 152 DDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQ 211
            +     +  + + LSE+++L   L      +        G  SY F       R  + +
Sbjct: 1   ANKGSKATERLKKKLSEQESL---LLLMSPSMAFRVHSRNG-KSYTFLISSDYERAEWRE 56

Query: 212 AFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTL 253
              E ++K   S S    E       M T S ++        
Sbjct: 57  NIREQQKKCFRSFSLTSVEL-----QMLTNSCVKLQTVHSIP 93



>gb|AAF61858.1| (AF192533) BCR-ABL fusion protein [Homo sapiens]
          Length = 101

 Score = 59.0 bits (140), Expect = 7e-08
 Identities = 11/54 (20%), Positives = 18/54 (32%), Gaps = 8/54 (14%)

Query: 214 DEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTL---NSCPEPSPEVW 264
            E ++K   S S    E       M T S ++           N   + SP ++
Sbjct: 1   REQQKKCFRSFSLTSVEL-----QMLTNSCVKLQTVHSIPLTINKEHDESPGLY 49



>ref|XP_005166.1| KIAA0294 gene product [Homo sapiens]
          Length = 916

 Score = 41.1 bits (94), Expect = 0.016
 Identities = 56/311 (18%), Positives = 102/311 (32%), Gaps = 75/311 (24%)

Query: 51  KDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKG 110
           K+R +F+  D+++C T+  +     R   S            +Y + W +PL   D I+ 
Sbjct: 209 KERRVFMLNDVLMCATVSSRPSHDSRVMSS-----------QRYLLKWSVPLGHVDAIEY 257

Query: 111 ASQATNRE-----NIQKAIS------------------------RLDEDLTTLGQMSKLS 141
            S A   E      +    S                         L  DL  +GQ+++L 
Sbjct: 258 GSSAGTGEHSRHLAVHPPESLAVVANAKPNKVYMGPGQLYQDLQNLLHDLNVIGQITQLI 317

Query: 142 ESLGFPHQSLDDAL-----RDLSAAMHRDLSE-KQALCYALSFPPTKLELCATRPEGTDS 195
            +L   +Q+L+ ++       L   + +   E + A C  +       +  + RP    +
Sbjct: 318 GNLKGNYQNLNQSVAHDWTSGLQRLILKKEDEIRAADCCRIQLQLPGKQDKSGRPTFFTA 377

Query: 196 YIFEFPHPDARLGFEQAFDEAKRKLAS----------------SKSCLDPEFLKAIPIMK 239
               F        +  +   AK  L                   K            ++ 
Sbjct: 378 VFNTFTPAIKES-WVNSLQMAKLALEEENHMGWFCVEDDGNHIKKEKHPLLVGHMPVMVA 436

Query: 240 TRSGMQFSCAA--PTLNSCPEPSPE--------VWVCNSDGYVGQVCLLSL-RAEPDVEA 288
            +   +  CAA  P      E  P+        +W+ +    +GQ+ ++S   + P V  
Sbjct: 437 KQQEFKIECAAYNPEPYLNNESQPDSFSTAHGFLWIGSCTHQMGQIAIVSFQNSTPKVIE 496

Query: 289 CIAVCSARILC 299
           C  V  +RILC
Sbjct: 497 CFNV-ESRILC 506



>ref|NP_055444.1| Rho guanine nucleotide exchange factor (GEF) 10 [Homo sapiens]
 dbj|BAA20754.1| (AB002292) KIAA0294 [Homo sapiens]
          Length = 1121

 Score = 41.1 bits (94), Expect = 0.016
 Identities = 56/311 (18%), Positives = 102/311 (32%), Gaps = 75/311 (24%)

Query: 51  KDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKG 110
           K+R +F+  D+++C T+  +     R   S            +Y + W +PL   D I+ 
Sbjct: 414 KERRVFMLNDVLMCATVSSRPSHDSRVMSS-----------QRYLLKWSVPLGHVDAIEY 462

Query: 111 ASQATNRE-----NIQKAIS------------------------RLDEDLTTLGQMSKLS 141
            S A   E      +    S                         L  DL  +GQ+++L 
Sbjct: 463 GSSAGTGEHSRHLAVHPPESLAVVANAKPNKVYMGPGQLYQDLQNLLHDLNVIGQITQLI 522

Query: 142 ESLGFPHQSLDDAL-----RDLSAAMHRDLSE-KQALCYALSFPPTKLELCATRPEGTDS 195
            +L   +Q+L+ ++       L   + +   E + A C  +       +  + RP    +
Sbjct: 523 GNLKGNYQNLNQSVAHDWTSGLQRLILKKEDEIRAADCCRIQLQLPGKQDKSGRPTFFTA 582

Query: 196 YIFEFPHPDARLGFEQAFDEAKRKLAS----------------SKSCLDPEFLKAIPIMK 239
               F        +  +   AK  L                   K            ++ 
Sbjct: 583 VFNTFTPAIKES-WVNSLQMAKLALEEENHMGWFCVEDDGNHIKKEKHPLLVGHMPVMVA 641

Query: 240 TRSGMQFSCAA--PTLNSCPEPSPE--------VWVCNSDGYVGQVCLLSL-RAEPDVEA 288
            +   +  CAA  P      E  P+        +W+ +    +GQ+ ++S   + P V  
Sbjct: 642 KQQEFKIECAAYNPEPYLNNESQPDSFSTAHGFLWIGSCTHQMGQIAIVSFQNSTPKVIE 701

Query: 289 CIAVCSARILC 299
           C  V  +RILC
Sbjct: 702 CFNV-ESRILC 711



>dbj|BAB13452.1| (AB046846) KIAA1626 protein [Homo sapiens]
          Length = 1284

 Score = 39.9 bits (91), Expect = 0.037
 Identities = 37/168 (22%), Positives = 63/168 (37%), Gaps = 22/168 (13%)

Query: 7   EAERHARVLQEIEAHIEGMED-------LQAPLRRFLRQEMVIEVKAIGGK------KDR 53
           E +R A  + EI+   + + D       L +  R+ L  E + E    G +      K+R
Sbjct: 507 EQKRLADQVAEIQQLTKSVSDRSSLNKLLTSGQRQLLLCETLTE-TVYGDRGQLIKSKER 565

Query: 54  SLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIK-GAS 112
            +FL  D++VC  +  K  + R                 KY + W   L    +++ G  
Sbjct: 566 RVFLLNDMLVCANINFKPANHRGQLEISSLVPLGP----KYVVKWNTALPQVQVVEVGQD 621

Query: 113 QATNRENIQKAISRLDEDLTTLGQMSKLSESLGFPH--QSLDDALRDL 158
             T  ++         +  +  GQ ++    LG P   Q L D  +DL
Sbjct: 622 GGTYDKDNVLIQHSGAKKASASGQ-AQNKVYLGPPRLFQELQDLQKDL 668



>pir||T03307 hypothetical protein AAB71662.1 - human (fragment)
 gb|AAB71662.1| (AF009205) unknown [Homo sapiens]
          Length = 988

 Score = 39.9 bits (91), Expect = 0.037
 Identities = 27/133 (20%), Positives = 49/133 (36%), Gaps = 40/133 (30%)

Query: 51  KDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKG 110
           K+R +F+  D+++C T+  +     R   S            +Y + W +PL   D I+ 
Sbjct: 310 KERRVFMLNDVLMCATVSSRPSHDSRVMSS-----------QRYLLKWSVPLGHVDAIEY 358

Query: 111 ASQATNRE-----NIQKAIS------------------------RLDEDLTTLGQMSKLS 141
            S A   E      +    S                         L  DL  +GQ+++L 
Sbjct: 359 GSSAGTGEHSRHLAVHPPESLAVVANAKPNKVYMGPGQLYQDLQNLLHDLNVIGQITQLI 418

Query: 142 ESLGFPHQSLDDA 154
            +L   +Q+L+ +
Sbjct: 419 GNLKGNYQNLNQS 431



>dbj|BAB12119.1| (AB047595) hypothetical protein [Macaca fascicularis]
          Length = 567

 Score = 39.1 bits (89), Expect = 0.063
 Identities = 38/168 (22%), Positives = 64/168 (37%), Gaps = 22/168 (13%)

Query: 7   EAERHARVLQEIEAHIEGMED-------LQAPLRRFLRQEMVIEVKAIGGK------KDR 53
           E +R A  + EI+   + + D       L +  R+ L  E + E    G +      K+R
Sbjct: 256 EQKRLADQVAEIQQLTKSVSDRSSLNKLLTSGQRQLLLCETLTE-TVYGDRGQLIKSKER 314

Query: 54  SLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIK-GAS 112
            +FL  D++VC  +  K  + R                 KY + W   L    +++ G  
Sbjct: 315 RVFLLNDMLVCANINFKPANHRGQLEISSLVPLGP----KYVVKWNTALPQVQVVEVGQD 370

Query: 113 QATNRENIQKAISRLDEDLTTLGQMSKLSESLGFPH--QSLDDALRDL 158
             T  ++         +  +T GQ ++    LG P   Q L D  +DL
Sbjct: 371 GGTYDKDNVLIQHAGAKKASTSGQ-AQNKVYLGPPRLFQELQDLQKDL 417



>dbj|BAA92600.1| (AB037783) KIAA1362 protein [Homo sapiens]
          Length = 699

 Score = 38.3 bits (87), Expect = 0.11
 Identities = 32/125 (25%), Positives = 58/125 (45%), Gaps = 9/125 (7%)

Query: 15  LQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKD---RSLFLFTDLIVCTTLKRKS 71
           L +I+  + G  ++  P R FL++ +++++     +K    R  FLF D ++ TT   +S
Sbjct: 402 LMQIQYSLNGHHEIVQPGRVFLKEGILMKLS----RKVMQPRMFFLFNDALLYTT-PVQS 456

Query: 72  GSLRRSSMSLYTAASVIDTASK-YKMLWKLPLEDADIIKGASQATNRENIQKAISRLDED 130
           G  + ++M       V     + Y+   K+   +   I  AS AT R+   +AISR  E+
Sbjct: 457 GMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSATERDEWLEAISRAIEE 516

Query: 131 LTTLG 135
                
Sbjct: 517 YAKKR 521



>ref|NP_060821.1| hypothetical protein FLJ11183 [Homo sapiens]
 dbj|BAA92052.1| (AK002045) unnamed protein product [Homo sapiens]
          Length = 432

 Score = 38.3 bits (87), Expect = 0.11
 Identities = 32/125 (25%), Positives = 58/125 (45%), Gaps = 9/125 (7%)

Query: 15  LQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKD---RSLFLFTDLIVCTTLKRKS 71
           L +I+  + G  ++  P R FL++ +++++     +K    R  FLF D ++ TT   +S
Sbjct: 72  LMQIQYSLNGHHEIVQPGRVFLKEGILMKLS----RKVMQPRMFFLFNDALLYTT-PVQS 126

Query: 72  GSLRRSSMSLYTAASVIDTASK-YKMLWKLPLEDADIIKGASQATNRENIQKAISRLDED 130
           G  + ++M       V     + Y+   K+   +   I  AS AT R+   +AISR  E+
Sbjct: 127 GMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSATERDEWLEAISRAIEE 186

Query: 131 LTTLG 135
                
Sbjct: 187 YAKKR 191



>dbj|BAA83062.1| (AB029033) KIAA1110 protein [Homo sapiens]
          Length = 740

 Score = 38.3 bits (87), Expect = 0.11
 Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 8/80 (10%)

Query: 9   ERHARVLQEIEAHIEGM-EDLQAPLRRFLRQEMVIEVKAIG-----GKKDRSLFLFTDLI 62
           E H   + ++E  I GM   L  P RR +    + EV  +          R +FLF DL+
Sbjct: 401 EDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFNDLL 460

Query: 63  VCTTL--KRKSGSLRRSSMS 80
           V   L  K+KS S      S
Sbjct: 461 VILKLCPKKKSSSTYTFCKS 480



>dbj|BAA97653.1| (AB018223) acetylspermidine oxidase [Candida boidinii]
          Length = 509

 Score = 37.9 bits (86), Expect = 0.14
 Identities = 37/214 (17%), Positives = 68/214 (31%), Gaps = 33/214 (15%)

Query: 59  TDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIK----GASQA 114
             L + T +K+ + S  R  +++ T  +  +    Y   + +      I+K         
Sbjct: 220 NKLYLNTEVKKITFSDWRKEITIKTKNTKTNKIDTYICKYIICTAPLSILKLQKNEVGSI 279

Query: 115 TNRENIQKAISRLDEDL--TTLGQMSKLSESLGFPHQS-----LDDALRDLSAAMHR--- 164
                + K IS   ++L  + LG++    + + +P  S     L D   ++   + R   
Sbjct: 280 EWSPKLPKQISSALDNLSFSALGKILFEFDEVFWPKDSDRFFCLPDYDAEMYNKVKRGDT 339

Query: 165 ------DLSEK--QALCYALSFPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQA---- 212
                   SEK  ++   A  F    L L   R  G  +      +P     + +A    
Sbjct: 340 NSGIEIRTSEKDIKSAPDAEGFTHPVLFLNVYRMNGAPALACLISNPL--TKWIEADPQN 397

Query: 213 -----FDEAKRKLASSKSCLDPEFLKAIPIMKTR 241
                      K+ SS      E      I  T 
Sbjct: 398 RAWPVIKPLLAKIVSSLPNAPKEIPAPKSITCTN 431



>ref|XP_007065.1| FERM, RhoGEF, and pleckstrin domain protein 1 [Homo sapiens]
          Length = 822

 Score = 37.6 bits (85), Expect = 0.19
 Identities = 15/52 (28%), Positives = 31/52 (58%), Gaps = 1/52 (1%)

Query: 15  LQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTT 66
           L E++  + G+++L  P R F+R   + ++   G ++ R  FLF D+++ T+
Sbjct: 517 LHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQ-RMFFLFNDVLLYTS 567



>pir||JC5795 CDEP protein - human
          Length = 1045

 Score = 37.6 bits (85), Expect = 0.19
 Identities = 15/52 (28%), Positives = 31/52 (58%), Gaps = 1/52 (1%)

Query: 15  LQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTT 66
           L E++  + G+++L  P R F+R   + ++   G ++ R  FLF D+++ T+
Sbjct: 740 LHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQ-RMFFLFNDVLLYTS 790



>ref|NP_005757.1| FERM, RhoGEF, and pleckstrin domain protein 1; chondrocyte-derived
           ezrin-like protein [Homo sapiens]
 dbj|BAA24267.1| (AB008430) CDEP [Homo sapiens]
          Length = 1045

 Score = 37.6 bits (85), Expect = 0.19
 Identities = 15/52 (28%), Positives = 31/52 (58%), Gaps = 1/52 (1%)

Query: 15  LQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTT 66
           L E++  + G+++L  P R F+R   + ++   G ++ R  FLF D+++ T+
Sbjct: 740 LHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQ-RMFFLFNDVLLYTS 790



>ref|XP_005638.1| vav 2 oncogene [Homo sapiens]
          Length = 878

 Score = 36.4 bits (82), Expect = 0.42
 Identities = 24/95 (25%), Positives = 40/95 (41%), Gaps = 5/95 (5%)

Query: 7   EAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIG----GKKDRSLFLFTDLI 62
           E +R    L++I      +E+LQ  L  F R ++  E+K        K+DR LFLF  ++
Sbjct: 375 EVKRDKETLRKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVV 434

Query: 63  VCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKML 97
           +    K  S  L +  + L       D  +   + 
Sbjct: 435 IVCKRKGYSYEL-KEIIELLFHKMTDDPMNNKDVK 468



>pir||A59235 unconventional myosin heavy chain MyoM - slime mold  (Dictyostelium
            discoideum)
 gb|AAD47903.1|AF090533_1 (AF090533) unconventional myosin heavy chain MyoM [Dictyostelium
            discoideum]
 dbj|BAA84604.1| (AB017910) myoM [Dictyostelium discoideum]
          Length = 1737

 Score = 36.4 bits (82), Expect = 0.42
 Identities = 35/173 (20%), Positives = 64/173 (36%), Gaps = 27/173 (15%)

Query: 2    VRSAEEAERHARVLQEIEAHIEGM-----EDLQAPLRRFLRQEMVIEVKAIGGKKD--RS 54
            V+S  EA+R   + Q+I      +      +L    R  L +  V  VK +  +    R+
Sbjct: 1566 VQSINEAKRTLELFQKIVDLQNSIDGLEDTNLMEQGRTLLMEGTVSAVKELNSEDSLSRT 1625

Query: 55   LFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLP--------LEDAD 106
            LFLF +LI+          +     ++ + A       K K+  K+P        + D D
Sbjct: 1626 LFLFNNLIL----------ICSFGTNVLSTAINQFKTKKLKLKAKIPISDSRLIFVSDTD 1675

Query: 107  IIKGASQATNRENIQKAISRLDEDLTTLGQMSKLSESLGFPHQSLDDALRDLS 159
             +K A +  N +     I   + D        ++   +    Q L +A +  +
Sbjct: 1676 SVKYALEIVNIKEDSNYILCFNNDQDRSKWFKQIKALIQ--EQKLSNAKKAAT 1726



>ref|NP_033526.1| Vav2 oncogene [Mus musculus]
 sp|Q60992|VAV2_MOUSE VAV2 PROTEIN
 gb|AAC52761.1| (U37017) Vav2 gene product [Mus musculus]
          Length = 868

 Score = 36.4 bits (82), Expect = 0.42
 Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 7   EAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIG----GKKDRSLFLFTDLI 62
           E +R    L++I      +E+LQ  L  F R ++  E+K        K+DR LFLF  ++
Sbjct: 370 EVKRDKETLKKISEFQCSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVV 429

Query: 63  VCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLW 98
           +    K  S  L+     L+   +     +K    W
Sbjct: 430 IVCKRKGYSYELKEVIELLFHKMTDDPMHNKDIKKW 465



>sp|Q55750|MFD_SYNY3 TRANSCRIPTION-REPAIR COUPLING FACTOR (TRCF)
 pir||S76549 transcription-repair coupling protein - Synechocystis sp.  (strain
           PCC 6803)
 dbj|BAA10395.1| (D64002) transcription-repair coupling factor [Synechocystis sp.]
          Length = 1199

 Score = 36.4 bits (82), Expect = 0.42
 Identities = 19/83 (22%), Positives = 33/83 (38%), Gaps = 6/83 (7%)

Query: 20  AHIEGMEDLQAPLRRFLRQEMVIEVKAI-GGKKDRSLFL-FT----DLIVCTTLKRKSGS 73
             IEG+E+L   LR+ +    +          +  S  L F     D++VCTT+      
Sbjct: 863 PRIEGIEELGGQLRQMVPSARIAIGHGQMEESELESTMLAFNDGEADILVCTTIIEAGLD 922

Query: 74  LRRSSMSLYTAASVIDTASKYKM 96
           + R +  +   A     A  Y++
Sbjct: 923 IPRVNTIIVEDAQKFGLAQLYQL 945



>ref|NP_003362.1| vav 2 oncogene; Oncogene VAV2 [Homo sapiens]
 sp|P52735|VAV2_HUMAN VAV2 PROTEIN
 pir||I51940 gene VAV2 protein - human
 gb|AAB34377.1| (S76992) VAV2=VAV oncogene homolog [human, fetal brain, Peptide,
           878 aa] [Homo sapiens]
          Length = 878

 Score = 36.4 bits (82), Expect = 0.42
 Identities = 24/95 (25%), Positives = 40/95 (41%), Gaps = 5/95 (5%)

Query: 7   EAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIG----GKKDRSLFLFTDLI 62
           E +R    L++I      +E+LQ  L  F R ++  E+K        K+DR LFLF  ++
Sbjct: 375 EVKRDKETLRKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVV 434

Query: 63  VCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKML 97
           +    K  S  L +  + L       D  +   + 
Sbjct: 435 IVCKRKGYSYEL-KEIIELLFHKMTDDPMNNKDVK 468



>ref|XP_007501.1| hypothetical protein FLJ10357 [Homo sapiens]
          Length = 300

 Score = 35.2 bits (79), Expect = 0.94
 Identities = 21/73 (28%), Positives = 31/73 (41%), Gaps = 6/73 (8%)

Query: 2   VRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKK--DRSLFLFT 59
           V+   E E   R L  +EA      DL+   +   R    +    I G+K   R +FLF 
Sbjct: 69  VQLLREQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTV----ICGRKKCLRHVFLFE 124

Query: 60  DLIVCTTLKRKSG 72
            L++ + LK   G
Sbjct: 125 HLLLFSKLKGPEG 137



>ref|XP_002741.1| KIAA0793 gene product [Homo sapiens]
          Length = 936

 Score = 35.2 bits (79), Expect = 0.94
 Identities = 17/52 (32%), Positives = 34/52 (64%), Gaps = 1/52 (1%)

Query: 15  LQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTT 66
           L E++  + G+E+L AP R F+R+  + ++   G ++ R  FLF+D+++ T+
Sbjct: 736 LTELQRDLVGIENLIAPGREFIREGCLHKLTKKGLQQ-RMFFLFSDMLLYTS 786



>dbj|BAB15753.1| (AK024463) FLJ00056 protein [Homo sapiens]
          Length = 1310

 Score = 35.2 bits (79), Expect = 0.94
 Identities = 21/73 (28%), Positives = 31/73 (41%), Gaps = 6/73 (8%)

Query: 2    VRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKK--DRSLFLFT 59
            V+   E E   R L  +EA      DL+   +   R    +    I G+K   R +FLF 
Sbjct: 1031 VQLLREQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTV----ICGRKKCLRHVFLFE 1086

Query: 60   DLIVCTTLKRKSG 72
             L++ + LK   G
Sbjct: 1087 HLLLFSKLKGPEG 1099



>ref|NP_060541.1| hypothetical protein FLJ10357 [Homo sapiens]
 dbj|BAA91563.1| (AK001219) unnamed protein product [Homo sapiens]
          Length = 278

 Score = 35.2 bits (79), Expect = 0.94
 Identities = 21/73 (28%), Positives = 31/73 (41%), Gaps = 6/73 (8%)

Query: 2   VRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKK--DRSLFLFT 59
           V+   E E   R L  +EA      DL+   +   R    +    I G+K   R +FLF 
Sbjct: 47  VQLLREQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTV----ICGRKKCLRHVFLFE 102

Query: 60  DLIVCTTLKRKSG 72
            L++ + LK   G
Sbjct: 103 HLLLFSKLKGPEG 115



>pir||T46359 hypothetical protein DKFZp434K1316.1 - human (fragment)
 emb|CAB70682.1| (AL137291) hypothetical protein [Homo sapiens]
          Length = 658

 Score = 35.2 bits (79), Expect = 0.94
 Identities = 21/73 (28%), Positives = 31/73 (41%), Gaps = 6/73 (8%)

Query: 2   VRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKK--DRSLFLFT 59
           V+   E E   R L  +EA      DL+   +   R    +    I G+K   R +FLF 
Sbjct: 400 VQLLREQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTV----ICGRKKCLRHVFLFE 455

Query: 60  DLIVCTTLKRKSG 72
            L++ + LK   G
Sbjct: 456 HLLLFSKLKGPEG 468



>ref|NP_055623.1| KIAA0793 gene product [Homo sapiens]
 dbj|BAA34513.1| (AB018336) KIAA0793 protein [Homo sapiens]
          Length = 1054

 Score = 35.2 bits (79), Expect = 0.94
 Identities = 17/52 (32%), Positives = 34/52 (64%), Gaps = 1/52 (1%)

Query: 15  LQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTT 66
           L E++  + G+E+L AP R F+R+  + ++   G ++ R  FLF+D+++ T+
Sbjct: 736 LTELQRDLVGIENLIAPGREFIREGCLHKLTKKGLQQ-RMFFLFSDMLLYTS 786



>dbj|BAA31629.1| (AB014554) KIAA0654 protein [Homo sapiens]
          Length = 1093

 Score = 35.2 bits (79), Expect = 0.94
 Identities = 34/146 (23%), Positives = 50/146 (33%), Gaps = 20/146 (13%)

Query: 111 ASQATNRENIQKAISRLDEDLTTL-GQMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEK 169
           A      E  +  + +L E L  L  QMS+L E LG  H+ L  A  + ++ + RDL E 
Sbjct: 135 AELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKA-EEANSKLQRDLKEA 193

Query: 170 QALCYALSFPPTKLELCATRP--------EGTDSYIFEFP--------HPDARLGFEQAF 213
            A    +    T LE              +  D    E            +      +  
Sbjct: 194 LAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWL 253

Query: 214 DEAKRKLASSKSCLDPEFLKAIPIMK 239
           D+AK+KL  +      E L  I    
Sbjct: 254 DDAKQKLQQTLQKA--ETLPEIEAQL 277



>ref|XP_001623.1| hypothetical protein FLJ10521 [Homo sapiens]
          Length = 476

 Score = 34.8 bits (78), Expect = 1.2
 Identities = 40/168 (23%), Positives = 66/168 (38%), Gaps = 27/168 (16%)

Query: 7   EAERHARVLQEIEAHIEGMED-------LQAPLRRFLRQEMVIEVKAIGGK------KDR 53
           E +R A  + EI+   + + D       L +  R+ L  E + E    G +      K+R
Sbjct: 31  EQKRLADQVAEIQQLTKSVSDRSSLNKLLTSGQRQLLLCETLTE-TVYGDRGQLIKSKER 89

Query: 54  SLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIK-GAS 112
            +FL  D++VC  +  K G L  SS+             KY + W   L    +++ G  
Sbjct: 90  RVFLLNDMLVCANINFK-GQLEISSLVPLGP--------KYVVKWNTALPQVQVVEVGQD 140

Query: 113 QATNRENIQKAISRLDEDLTTLGQMSKLSESLGFPH--QSLDDALRDL 158
             T  ++         +  +  GQ ++    LG P   Q L D  +DL
Sbjct: 141 GGTYDKDNVLIQHSGAKKASASGQ-AQNKVYLGPPRLFQELQDLQKDL 187



>dbj|BAA92629.1| (AB037812) KIAA1391 protein [Homo sapiens]
          Length = 1194

 Score = 34.8 bits (78), Expect = 1.2
 Identities = 11/26 (42%), Positives = 16/26 (61%)

Query: 43  EVKAIGGKKDRSLFLFTDLIVCTTLK 68
           E+K    +++R LFLF DL V   +K
Sbjct: 96  ELKRGLQRQERHLFLFNDLFVVAKIK 121



>ref|NP_060595.1| hypothetical protein FLJ10521 [Homo sapiens]
 dbj|BAA91663.1| (AK001383) unnamed protein product [Homo sapiens]
          Length = 596

 Score = 34.8 bits (78), Expect = 1.2
 Identities = 40/168 (23%), Positives = 66/168 (38%), Gaps = 27/168 (16%)

Query: 7   EAERHARVLQEIEAHIEGMED-------LQAPLRRFLRQEMVIEVKAIGGK------KDR 53
           E +R A  + EI+   + + D       L +  R+ L  E + E    G +      K+R
Sbjct: 31  EQKRLADQVAEIQQLTKSVSDRSSLNKLLTSGQRQLLLCETLTE-TVYGDRGQLIKSKER 89

Query: 54  SLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIK-GAS 112
            +FL  D++VC  +  K G L  SS+             KY + W   L    +++ G  
Sbjct: 90  RVFLLNDMLVCANINFK-GQLEISSLVPLGP--------KYVVKWNTALPQVQVVEVGQD 140

Query: 113 QATNRENIQKAISRLDEDLTTLGQMSKLSESLGFPH--QSLDDALRDL 158
             T  ++         +  +  GQ ++    LG P   Q L D  +DL
Sbjct: 141 GGTYDKDNVLIQHSGAKKASASGQ-AQNKVYLGPPRLFQELQDLQKDL 187



CPU time:    33.89 user secs.       1.53 sys. secs         35.42 total secs.

  Database: nr
    Posted date:  Dec 24, 2000  7:24 PM
  Number of letters in database: 189,012,571
  Number of sequences in database:  598,029
  
Lambda     K      H
   0.319    0.133    0.386 

Gapped
Lambda     K      H
   0.270   0.0460    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85565638
Number of Sequences: 598029
Number of extensions: 2962804
Number of successful extensions: 10981
Number of sequences better than 10.0: 108
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 82
Number of HSP's that attempted gapping in prelim test: 10810
Number of HSP's gapped (non-prelim): 122
length of query: 300
length of database: 189,012,571
effective HSP length: 57
effective length of query: 243
effective length of database: 154,924,918
effective search space: 37646755074
effective search space used: 37646755074
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 71 (32.1 bits)