Legend:
Sequences with E-value BETTER than threshold 351 1e-95
311 1e-83
310 2e-83
306 3e-82
306 3e-82
306 3e-82
306 3e-82
304 2e-81
304 2e-81
298 1e-79
289 5e-77
289 6e-77
287 2e-76
285 7e-76
262 8e-69
253 4e-66
253 4e-66
253 4e-66
248 2e-64
248 2e-64
247 3e-64
243 4e-63
239 9e-62
238 1e-61
237 3e-61
237 3e-61
236 7e-61
232 8e-60
230 3e-59
230 3e-59
230 3e-59
230 3e-59
230 4e-59
229 7e-59
228 1e-58
227 3e-58
220 3e-56
215 1e-54
213 5e-54
213 5e-54
212 1e-53
212 1e-53
211 2e-53
209 5e-53
209 5e-53
208 1e-52
206 8e-52
204 3e-51
201 2e-50
199 1e-49
Alignments
>dbj|BAB15128.1| (AK025429) unnamed protein product [Homo sapiens]
Length = 274
Score = 351 bits (891), Expect = 1e-95
Identities = 168/213 (78%), Positives = 168/213 (78%)
Query: 325 MKAALQVSMNDGLSFXXXXXXXXXXHCSDGSXXXXXXXXXXXXXXXXXXXXXXPLCCTVI 384
MKAALQVSMNDGLSF HCSDGS PLCCTVI
Sbjct: 1 MKAALQVSMNDGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVI 60
Query: 385 IKXXXXXXXXXXXXXDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKL 444
IK DDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKL
Sbjct: 61 IKEVPPPPAEESEEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKL 120
Query: 445 EKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSV 504
EKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSV
Sbjct: 121 EKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSV 180
Query: 505 MRPQPGDTGRCINFTRVKNNQPAKYPLNNAYHT 537
MRPQPGDTGRCINFTRVKNNQPAKYPLNNAYHT
Sbjct: 181 MRPQPGDTGRCINFTRVKNNQPAKYPLNNAYHT 213
>ref|NP_032427.1| integrin alpha M (Cd11b); Mac-1 alpha; CD11B (p170); macrophage
antigen alpha; complement component receptor 3 alpha-a
(CR3A) [Mus musculus]
sp|P05555|ITAM_MOUSE CELL SURFACE GLYCOPROTEIN MAC-1 ALPHA SUBUNIT PRECURSOR (CR-3 ALPHA
CHAIN) (CD11B) (LEUKOCYTE ADHESION RECEPTOR MO1)
(INTEGRIN ALPHA-M)
pir||S00551 leukocyte surface glycoprotein Mac-1 alpha chain precursor - mouse
emb|CAA30479.1| (X07640) Mac-1 alpha-chain precursor (AA -16 to 1134) [Mus
musculus]
Length = 1153
Score = 311 bits (790), Expect = 1e-83
Identities = 49/255 (19%), Positives = 94/255 (36%), Gaps = 21/255 (8%)
Query: 46 RLPVALTATLVLICAGQ---GGRREDGGPACYGG-FDLYFILDKSGSVLH-HWNEIYYFV 100
+ + L + + + C D+ F++D SGS+ + + ++ FV
Sbjct: 114 KENTYVNGLCYLFGSNLLRPPQQFPEALRECPQQESDIVFLIDGSGSINNIDFQKMKEFV 173
Query: 101 EQLAHKFISPQLRMSFIVFSTRGTTLMKLTED-REQIRQGLEELQKVLPGGDTYMHEGFE 159
+ +F + S + +S + R + K L G T G
Sbjct: 174 STVMEQFKKSKTLFSLMQYSDEFRIHFTFNDFKRNPSPRSHVSPIKQL-NGRTKTASGIR 232
Query: 160 RASEQIYYENRQGYRT-ASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN 218
+ +++++ A +++ +TDGE D Y + + G I Y +GV +
Sbjct: 233 KVVRELFHKTNGARENAAKILVVITDGEKFGDPLDY-KDVIPEADRAGVIRYVIGVGNAF 291
Query: 219 -------ETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESF 271
E + +HVF V D F+AL I + + +K I A E + + SF
Sbjct: 292 NKPQSRRELDTIASKPAGEHVFQV-DNFEALNTIQNQLQEK----IFAIEGTQTGSTSSF 346
Query: 272 QVVVRGNGFRHARNV 286
+ + GF +
Sbjct: 347 EHEMSQEGFSASITS 361
>gb|AAF81280.1| (AF268593) integrin beta 2 alpha subunit; CD11b [Rattus norvegicus]
Length = 1151
Score = 310 bits (787), Expect = 2e-83
Identities = 51/255 (20%), Positives = 94/255 (36%), Gaps = 21/255 (8%)
Query: 46 RLPVALTATLVLICAGQ---GGRREDGGPACYGG-FDLYFILDKSGSVLH-HWNEIYYFV 100
+ + L + + + C ++ F++D SGS+ + ++ FV
Sbjct: 114 KENTYVNGLCYLFGSNLLRKPQQFPEALRGCPQQESNIAFLIDGSGSINTIDFQKMKEFV 173
Query: 101 EQLAHKFISPQLRMSFIVFSTRGTTLMKLTED-REQIRQGLEELQKVLPGGDTYMHEGFE 159
+ +F + S + +S T + R + + L G T G
Sbjct: 174 STVMDQFQKSKTLFSLMQYSDEFRTHFTFNDFKRNPDPKSHVRPIRQL-NGRTKTASGIR 232
Query: 160 RASEQIYYENRQGYRT-ASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN 218
+ +++ + A +++ +TDGE D Y E + + G I Y +GV +
Sbjct: 233 KVVRELFQKINGARDNAAKILVVITDGEKFGDPLNY-EDVIPEAEEAGIIRYVIGVGNAF 291
Query: 219 -------ETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESF 271
E + DHVF V D F+AL I + + +K I A E + + SF
Sbjct: 292 HKPQSRRELDTIASKPAGDHVFQV-DNFEALNTIRNQLQEK----IFAIEGTQTGSTSSF 346
Query: 272 QVVVRGNGFRHARNV 286
+ + GF A
Sbjct: 347 EHEMSQEGFSAAITS 361
>gb|AAA59903.1| (J04145) neutrophil adherence receptor alpha-M subunit [Homo
sapiens]
Length = 1145
Score = 306 bits (777), Expect = 3e-82
Identities = 52/253 (20%), Positives = 91/253 (35%), Gaps = 19/253 (7%)
Query: 47 LPVALTATLVLICAG---QGGRREDGGPACYGG-FDLYFILDKSGSVLHH-WNEIYYFVE 101
+ L + Q + + C D+ F++D SGS++ H + + FV
Sbjct: 107 ENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVS 166
Query: 102 QLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERA 161
+ + + S + +S E + G T+ G +
Sbjct: 167 TVMEQLKKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKV 226
Query: 162 SEQIYYENRQGYRTA-SVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN-- 218
+++ + A +++ +TDGE D Y E + G I Y +GV D
Sbjct: 227 VRELFNITNGARKNAFKILVVITDGEKFGDPLGY-EDVIPEADREGVIRYVIGVGDAFRS 285
Query: 219 -----ETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQV 273
E +DHVF VN F+AL+ I + + +K I A E + + SF+
Sbjct: 286 EKSRQELNTIASKPPRDHVFQVN-NFEALKTIQNQLREK----IFAIEGTQTGSSSSFEH 340
Query: 274 VVRGNGFRHARNV 286
+ GF A
Sbjct: 341 EMSQEGFSAAITS 353
>ref|NP_000623.1| integrin alpha M; antigen CD11b (p170); macrophage antigen alpha
polypeptide; neutrophil adherence receptor alpha-M
subunit; Integrin, alpha-M (complement component
receptor-3, alpha; antigen CD11B (p170); macrophage
antigen, alpha polypeptide); compl>
gb|AAA59491.1| (M18044) leukocyte adhesion glycoprotein precursor [Homo sapiens]
Length = 1152
Score = 306 bits (777), Expect = 3e-82
Identities = 52/253 (20%), Positives = 91/253 (35%), Gaps = 19/253 (7%)
Query: 47 LPVALTATLVLICAG---QGGRREDGGPACYGG-FDLYFILDKSGSVLHH-WNEIYYFVE 101
+ L + Q + + C D+ F++D SGS++ H + + FV
Sbjct: 115 ENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVS 174
Query: 102 QLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERA 161
+ + + S + +S E + G T+ G +
Sbjct: 175 TVMEQLKKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKV 234
Query: 162 SEQIYYENRQGYRTA-SVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN-- 218
+++ + A +++ +TDGE D Y E + G I Y +GV D
Sbjct: 235 VRELFNITNGARKNAFKILVVITDGEKFGDPLGY-EDVIPEADREGVIRYVIGVGDAFRS 293
Query: 219 -----ETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQV 273
E +DHVF VN F+AL+ I + + +K I A E + + SF+
Sbjct: 294 EKSRQELNTIASKPPRDHVFQVN-NFEALKTIQNQLREK----IFAIEGTQTGSSSSFEH 348
Query: 274 VVRGNGFRHARNV 286
+ GF A
Sbjct: 349 EMSQEGFSAAITS 361
>sp|P11215|ITAM_HUMAN CELL SURFACE GLYCOPROTEIN MAC-1 ALPHA SUBUNIT PRECURSOR (CR-3 ALPHA
CHAIN) (CD11B) (LEUKOCYTE ADHESION RECEPTOR MO1)
(INTEGRIN ALPHA-M) (NEUTROPHIL ADHERENCE RECEPTOR)
gb|AAB24821.1| (S52228) leukocyte integrin alpha chain [human, Peptide, 1152 aa]
[Homo sapiens]
Length = 1152
Score = 306 bits (777), Expect = 3e-82
Identities = 52/253 (20%), Positives = 91/253 (35%), Gaps = 19/253 (7%)
Query: 47 LPVALTATLVLICAG---QGGRREDGGPACYGG-FDLYFILDKSGSVLHH-WNEIYYFVE 101
+ L + Q + + C D+ F++D SGS++ H + + FV
Sbjct: 115 ENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVS 174
Query: 102 QLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERA 161
+ + + S + +S E + G T+ G +
Sbjct: 175 TVMEQLKKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKV 234
Query: 162 SEQIYYENRQGYRTA-SVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN-- 218
+++ + A +++ +TDGE D Y E + G I Y +GV D
Sbjct: 235 VRELFNITNGARKNAFKILVVITDGEKFGDPLGY-EDVIPEADREGVIRYVIGVGDAFRS 293
Query: 219 -----ETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQV 273
E +DHVF VN F+AL+ I + + +K I A E + + SF+
Sbjct: 294 EKSRQELNTIASKPPRDHVFQVN-NFEALKTIQNQLREK----IFAIEGTQTGSSSSFEH 348
Query: 274 VVRGNGFRHARNV 286
+ GF A
Sbjct: 349 EMSQEGFSAAITS 361
>pir||RWHU1B cell surface glycoprotein CD11b precursor - human
gb|AAA59544.1| (J03925) glycoprotein Mac-1 [Homo sapiens]
Length = 1153
Score = 306 bits (777), Expect = 3e-82
Identities = 52/253 (20%), Positives = 91/253 (35%), Gaps = 19/253 (7%)
Query: 47 LPVALTATLVLICAG---QGGRREDGGPACYGG-FDLYFILDKSGSVLHH-WNEIYYFVE 101
+ L + Q + + C D+ F++D SGS++ H + + FV
Sbjct: 115 ENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVS 174
Query: 102 QLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERA 161
+ + + S + +S E + G T+ G +
Sbjct: 175 TVMEQLKKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKV 234
Query: 162 SEQIYYENRQGYRTA-SVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN-- 218
+++ + A +++ +TDGE D Y E + G I Y +GV D
Sbjct: 235 VRELFNITNGARKNAFKILVVITDGEKFGDPLGY-EDVIPEADREGVIRYVIGVGDAFRS 293
Query: 219 -----ETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQV 273
E +DHVF VN F+AL+ I + + +K I A E + + SF+
Sbjct: 294 EKSRQELNTIASKPPRDHVFQVN-NFEALKTIQNQLREK----IFAIEGTQTGSSSSFEH 348
Query: 274 VVRGNGFRHARNV 286
+ GF A
Sbjct: 349 EMSQEGFSAAITS 361
>pir||RWHU1C cell surface glycoprotein CD11c precursor - human
Length = 1163
Score = 304 bits (770), Expect = 2e-81
Identities = 57/251 (22%), Positives = 96/251 (37%), Gaps = 17/251 (6%)
Query: 48 PVALTATLVLICAGQ-GGRREDGGPACYGG-FDLYFILDKSGSVLH-HWNEIYYFVEQLA 104
+ LT L+ Q R C D+ F++D SGS+ ++ + FV +
Sbjct: 119 NMYLTGLCFLLGPTQLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVI 178
Query: 105 HKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQ 164
+F P + S + FS + T E R G TY + +
Sbjct: 179 SQFQRPSTQFSLMQFSNKFQTHFTFEEFRRTSNPLSLLASVHQLQGFTYTATAIQNVVHR 238
Query: 165 IYYENRQGYRTA-SVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN----- 218
+++ + R A ++I +TDG+ D Y + + G I Y +GV
Sbjct: 239 LFHASYGARRDATKILIVITDGKKEGDSLDY-KDVIPMADAAGIIRYAIGVGLAFQNRNS 297
Query: 219 --ETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVR 276
E S++H+F V D F AL+ I + + +K I A E + + SF++ +
Sbjct: 298 WKELNDIASKPSQEHIFKVED-FDALKDIQNQLKEK----IFAIEGTETTSSSSFELEMA 352
Query: 277 GNGFRHARNVD 287
GF D
Sbjct: 353 QEGFSAVFTPD 363
>ref|NP_000878.1| integrin alpha X precursor [Homo sapiens]
sp|P20702|ITAX_HUMAN LEUKOCYTE ADHESION GLYCOPROTEIN P150,95 ALPHA CHAIN PRECURSOR
(LEUKOCYTE ADHESION RECEPTOR P150,95) (CD11C) (LEU M5)
(INTEGRIN ALPHA-X)
emb|CAA68283.1| (Y00093) leukocyte adhesion glycoprotein [Homo sapiens]
gb|AAA59180.1| (M81695) ITGAX [Homo sapiens]
Length = 1163
Score = 304 bits (770), Expect = 2e-81
Identities = 57/251 (22%), Positives = 96/251 (37%), Gaps = 17/251 (6%)
Query: 48 PVALTATLVLICAGQ-GGRREDGGPACYGG-FDLYFILDKSGSVLH-HWNEIYYFVEQLA 104
+ LT L+ Q R C D+ F++D SGS+ ++ + FV +
Sbjct: 119 NMYLTGLCFLLGPTQLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVI 178
Query: 105 HKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQ 164
+F P + S + FS + T E R G TY + +
Sbjct: 179 SQFQRPSTQFSLMQFSNKFQTHFTFEEFRRTSNPLSLLASVHQLQGFTYTATAIQNVVHR 238
Query: 165 IYYENRQGYRTA-SVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN----- 218
+++ + R A ++I +TDG+ D Y + + G I Y +GV
Sbjct: 239 LFHASYGARRDATKILIVITDGKKEGDSLDY-KDVIPMADAAGIIRYAIGVGLAFQNRNS 297
Query: 219 --ETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVR 276
E S++H+F V D F AL+ I + + +K I A E + + SF++ +
Sbjct: 298 WKELNDIASKPSQEHIFKVED-FDALKDIQNQLKEK----IFAIEGTETTSSSSFELEMA 352
Query: 277 GNGFRHARNVD 287
GF D
Sbjct: 353 QEGFSAVFTPD 363
>gb|AAA51620.1| (M29487) integrin alpha subunit precursor [Homo sapiens]
Length = 1163
Score = 298 bits (756), Expect = 1e-79
Identities = 56/251 (22%), Positives = 95/251 (37%), Gaps = 17/251 (6%)
Query: 48 PVALTATLVLICAGQ-GGRREDGGPACYGG-FDLYFILDKSGSVLH-HWNEIYYFVEQLA 104
+ LT L+ Q R C D+ F++D SGS+ ++ + FV +
Sbjct: 119 NMYLTGLCFLLGPTQLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVI 178
Query: 105 HKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQ 164
+F P + S + FS + T + E R G TY + +
Sbjct: 179 SQFQRPSTQFSLMQFSNKFQTHLTFEEFRRTSNPLSLLASVHQLQGFTYTATAIQNVVHR 238
Query: 165 IYYENRQGYRTA-SVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN----- 218
+++ + R A ++I +TDG+ D Y + + G I Y +GV
Sbjct: 239 LFHASYGARRDATKILIVITDGKKEGDTLDY-KDVIPMADAAGIIRYAIGVGLAFQNRNS 297
Query: 219 --ETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVR 276
E S++H+F V D F AL+ I + +K I E + + SF++ +
Sbjct: 298 WKELNDIASKPSQEHIFKVED-FDALKDIQTQLREK----IFPIEGTETTSSSSFELEMA 352
Query: 277 GNGFRHARNVD 287
GF D
Sbjct: 353 QEGFSAVFTPD 363
>gb|AAB38547.1| (U37028) leukointegrin alpha d chain [Homo sapiens]
Length = 1162
Score = 289 bits (733), Expect = 5e-77
Identities = 60/253 (23%), Positives = 100/253 (38%), Gaps = 18/253 (7%)
Query: 47 LPVALTATLVLICAGQG--GRREDGGPACY-GGFDLYFILDKSGSVLHH-WNEIYYFVEQ 102
+ +L+ + D P C D+ F++D SGS+ + +N++ FV+
Sbjct: 116 ENSYSKGSCLLLGSRWEIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQA 175
Query: 103 LAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERAS 162
+ +F + + +S T+ R Q V G T+ G
Sbjct: 176 VMGQFEGTDTLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGILTVV 235
Query: 163 EQIYYENRQGYRTA-SVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN--- 218
Q+++ ++A ++I +TDG+ ++D YS ++ G I Y +GV
Sbjct: 236 TQLFHHKNGARKSAKKILIVITDGQKYKDPLEYS-DVIPQAEKAGIIRYAIGVGHAFQGP 294
Query: 219 ----ETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVV 274
E A +DHVF V D F AL I + +K I A E + A SFQ
Sbjct: 295 TARQELNTISSAPPQDHVFKV-DNFAALGSIQKQLQEK----IYAVEGTQSRASSSFQHE 349
Query: 275 VRGNGFRHARNVD 287
+ GF A +D
Sbjct: 350 MSQEGFSTALTMD 362
>gb|AAB16869.1| (U40072) CD11b [Sus scrofa]
Length = 920
Score = 289 bits (732), Expect = 6e-77
Identities = 50/235 (21%), Positives = 90/235 (38%), Gaps = 18/235 (7%)
Query: 63 GGRREDGGPACYGG-FDLYFILDKSGSVLH-HWNEIYYFVEQLAHKFISPQLRMSFIVFS 120
+ + C D+ F++D SGS+ + + FV + +F + + + +S
Sbjct: 1 PQKFPEALRGCPQQESDIAFLIDGSGSINRLDFQRMKEFVSTVMGQFQKSKTLFALMQYS 60
Query: 121 TRGTTLMKLTED-REQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTA-SV 178
T + R + L + L G T+ G + ++++ A +
Sbjct: 61 EDFYTHFTFNDFKRNPSPKLLVRPIRQLL-GRTHTATGIRKVVRELFHSKSGARENALKI 119
Query: 179 IIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN-------ETQLARIADSKDH 231
++ +TDGE D Y E + G I Y +GV D E DH
Sbjct: 120 LVVITDGEKFGDPLGY-EDVIPEADRKGVIRYVIGVGDAFNSWKSREELNTIASKPCGDH 178
Query: 232 VFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNV 286
VF VN F+A++ I + + +K+ A E + + SF+ + GF A
Sbjct: 179 VFQVN-NFEAVKTIQNQLQEKT----FAIEGTQTGSTSSFECEMSQEGFSAAITS 228
>gb|AAF21241.1|AF021334_1 (AF021334) alpha D integrin [Rattus norvegicus]
Length = 1161
Score = 287 bits (727), Expect = 2e-76
Identities = 60/252 (23%), Positives = 99/252 (38%), Gaps = 18/252 (7%)
Query: 48 PVALTATLVLICAGQG--GRREDGGPACYGG-FDLYFILDKSGSVLH-HWNEIYYFVEQL 103
+ + +L+ + P C D+ F++D SGS+ + ++ FV+ L
Sbjct: 119 NMYAKGSCLLLGSSLQFIQAVPASMPECPRQEMDIAFLIDGSGSINQRDFAQMKDFVKAL 178
Query: 104 AHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASE 163
+F S S + +S T TE + + V G TY G E
Sbjct: 179 MGEFASTSTLFSLMQYSNILKTHFTFTEFKNILDPQSLVDPIVQLQGLTYTATGIRTVME 238
Query: 164 QIYYENRQGYRTA-SVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN---- 218
++++ ++A +++ +TDG+ + D YS + G I Y +GV D
Sbjct: 239 ELFHSKNGSRKSAKKILLVITDGQKYRDPLEYS-DVIPAADKAGIIRYAIGVGDAFQEPT 297
Query: 219 ---ETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVV 275
E A +DHVF V F AL+ I + +K I A E + + SFQ +
Sbjct: 298 ALKELNTIGSAPPQDHVFKVG-NFAALRSIQRQLQEK----IFAIEGTQSRSSSSFQHEM 352
Query: 276 RGNGFRHARNVD 287
GF A D
Sbjct: 353 SQEGFSSALTSD 364
>ref|NP_067309.1| integrin alpha X (Cd11c); integrin aX; CD11C (p150) alpha
polypeptide [Mus musculus]
gb|AAF23492.1|AF211864_1 (AF211864) leukocyte adhesion glycoprotein p150,95 alpha integrin
subunit [Mus musculus]
Length = 1169
Score = 285 bits (723), Expect = 7e-76
Identities = 51/254 (20%), Positives = 88/254 (34%), Gaps = 18/254 (7%)
Query: 46 RLPVALTATLVLICAG--QGGRREDGGPACYGG-FDLYFILDKSGSVLH-HWNEIYYFVE 101
R + LT L+ + Q C D+ F++D SGS+ + ++ FV+
Sbjct: 117 RENIYLTGLCFLLSSSFKQSQNFPTAQQECPKQDQDIVFLIDGSGSISSTDFEKMLDFVK 176
Query: 102 QLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERA 161
+ + P R S + FS G TY +
Sbjct: 177 AVMSQLQRPSTRFSLMQFSDYFRVHFTFNNFISTSSPLSLLGSVRQLRGYTYTASAIKHV 236
Query: 162 SEQIYYENRQGYRTA-SVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN-- 218
+++ + A V+I +TDG D Y + + I Y +GV
Sbjct: 237 ITELFTTQSGARQDATKVLIVITDGRKQGDNLSY-DSVIPMAEAASIIRYAIGVGKAFYN 295
Query: 219 -----ETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQV 273
E + S ++VF V F AL+ I + + +K I A E + + +F++
Sbjct: 296 EHSKQELKAIASMPSHEYVFSVE-NFDALKDIENQLKEK----IFAIEGTETPSSSTFEL 350
Query: 274 VVRGNGFRHARNVD 287
+ GF D
Sbjct: 351 EMSQEGFSAVFTPD 364
>pir||A45974 collagen alpha 1(XIV) chain precursor, short form 2 - chicken
Length = 1747
Score = 262 bits (663), Expect = 8e-69
Identities = 52/269 (19%), Positives = 95/269 (34%), Gaps = 27/269 (10%)
Query: 50 ALTATLVLICAGQGGRREDGGPACYGGFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKFI 108
A+ A V GQG PA D+ ++D S S+ ++ + F+E L +F
Sbjct: 17 AVAAYSVSDAQGQGNLFTCKTPAIA---DIVILVDGSWSIGRFNFRLVRLFLENLVSRFN 73
Query: 109 --SPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQ 164
S + R+ +S L + + + + + LP GG+T E
Sbjct: 74 VGSEKTRVGLAQYSGDPRIEWHL--NAYGTKDAVLDADRNLPYKGGNTLTGLALTYILEN 131
Query: 165 IYYENRQGYR-TASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDF--NETQ 221
+ + + I +TDG+ +D+ A R+ G ++ +GVK+ NE +
Sbjct: 132 CFKPEAGARPGVSKIGILITDGKSQDDVI----PPAKNLREAGIELFAIGVKNADINELK 187
Query: 222 LARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFR 281
HV+ V D F + I+ + + C + E +
Sbjct: 188 EIASEPDSTHVYNVAD-FNFMNSIVEGLTRTVCSRVEEQEKEIKGTIAA-----SLGAPT 241
Query: 282 HARNVDRVLCSFKINDSVTLNEKPFSVED 310
D F+++ + P VE
Sbjct: 242 DLVTSDITARGFRVSWT----HSPGKVEK 266
Score = 232 bits (586), Expect = 8e-60
Identities = 59/266 (22%), Positives = 106/266 (39%), Gaps = 23/266 (8%)
Query: 67 EDGGPACYG-GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF--ISPQ-LRMSFIVFST 121
C DL F++D S S+ ++N+I F+ I P +++ I FS
Sbjct: 914 PPAKEVCKAAKADLVFLVDGSWSIGDDNFNKIISFLYSTVGALDKIGPDGTQVAIIQFSD 973
Query: 122 RGTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGYR-TASV 178
T KL + + ++ L E + + GG+T + + A E ++ + V
Sbjct: 974 DPRTEFKL--NAYKTKETLLEAIQQIAYKGGNTKTGKAIKHAREVLFTGEAGMRKGIPKV 1031
Query: 179 IIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQL--ARIADSKDHVFPVN 236
++ +TDG +D+ + + + G + +GV D + ++L S+ HVF V
Sbjct: 1032 LVVITDGRSQDDVN----KVSREMQLDGFSFFAIGVADADYSELVNIGSKPSERHVFFV- 1086
Query: 237 DGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKIN 296
D F A I ++ C A P G++F GF+ V F
Sbjct: 1087 DDFDAFTKIEDELITFVCETASATCPLVFKDGDNF------AGFKMMEMFGLVEKEFSAI 1140
Query: 297 DSVTLNEKPFSVEDTYLLCPAPILKE 322
D V++ F+V Y L ++ +
Sbjct: 1141 DGVSMEPGTFNVYPCYRLHKDALVSQ 1166
>pir||S31211 collagen alpha 1(XIV) chain precursor - chicken
Length = 814
Score = 253 bits (640), Expect = 4e-66
Identities = 48/258 (18%), Positives = 89/258 (33%), Gaps = 27/258 (10%)
Query: 61 GQGGRREDGGPACYGGFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKFI--SPQLRMSFI 117
+G PA D+ ++D S S+ ++ + F+E L F S + R+
Sbjct: 144 PEGNLFTCKTPAIA---DIVILVDGSWSIGRFNFRLVRLFLENLVSAFNVGSEKTRVGLA 200
Query: 118 VFSTRGTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGYR- 174
+S L + + + + + LP GG+T E +
Sbjct: 201 QYSGDPRIEWHL--NAYGTKDAVLDAVRNLPYKGGNTLTGLALTYILENSFKPEAGARPG 258
Query: 175 TASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDF--NETQLARIADSKDHV 232
+ + I +TDG+ +D+ A RD G ++ +GVK+ NE + HV
Sbjct: 259 VSKIGILITDGKSQDDVI----PPAKNLRDAGIELFAIGVKNADINELKEIASEPDSTHV 314
Query: 233 FPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCS 292
+ V D F + I+ + + C + E + D
Sbjct: 315 YNVAD-FNFMNSIVEGLTRTVCSRVEEQEKEIKGTIAA-----SLGAPTDLVTSDITARG 368
Query: 293 FKINDSVTLNEKPFSVED 310
F+++ + P VE
Sbjct: 369 FRVSWT----HSPGKVEK 382
>pir||S31212 collagen alpha 1(XIV) chain precursor, short form - chicken
emb|CAA50063.1| (X70792) collagen XIV [Gallus gallus]
Length = 1857
Score = 253 bits (640), Expect = 4e-66
Identities = 48/258 (18%), Positives = 89/258 (33%), Gaps = 27/258 (10%)
Query: 61 GQGGRREDGGPACYGGFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKFI--SPQLRMSFI 117
+G PA D+ ++D S S+ ++ + F+E L F S + R+
Sbjct: 144 PEGNLFTCKTPAIA---DIVILVDGSWSIGRFNFRLVRLFLENLVSAFNVGSEKTRVGLA 200
Query: 118 VFSTRGTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGYR- 174
+S L + + + + + LP GG+T E +
Sbjct: 201 QYSGDPRIEWHL--NAYGTKDAVLDAVRNLPYKGGNTLTGLALTYILENSFKPEAGARPG 258
Query: 175 TASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDF--NETQLARIADSKDHV 232
+ + I +TDG+ +D+ A RD G ++ +GVK+ NE + HV
Sbjct: 259 VSKIGILITDGKSQDDVI----PPAKNLRDAGIELFAIGVKNADINELKEIASEPDSTHV 314
Query: 233 FPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCS 292
+ V D F + I+ + + C + E + D
Sbjct: 315 YNVAD-FNFMNSIVEGLTRTVCSRVEEQEKEIKGTIAA-----SLGAPTDLVTSDITARG 368
Query: 293 FKINDSVTLNEKPFSVED 310
F+++ + P VE
Sbjct: 369 FRVSWT----HSPGKVEK 382
Score = 230 bits (581), Expect = 3e-59
Identities = 58/266 (21%), Positives = 105/266 (38%), Gaps = 23/266 (8%)
Query: 67 EDGGPACYG-GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF--ISPQ-LRMSFIVFST 121
C DL F++D S S+ ++N+I F+ I P +++ I FS
Sbjct: 1030 PPAKEVCKAAKADLVFLVDGSWSIGDDNFNKIISFLYSTVGALDKIGPDGTQVAIIQFSD 1089
Query: 122 RGTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGYR-TASV 178
T KL + + ++ L E + + GG+T + + A E ++ + V
Sbjct: 1090 DPRTEFKL--NAYKTKETLLEAIQQIAYKGGNTKTGKAIKHAREVLFTGEAGMRKGIPKV 1147
Query: 179 IIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQL--ARIADSKDHVFPVN 236
++ +TDG +D+ + + + G + +GV D + ++L S+ HVF V
Sbjct: 1148 LVVITDGRSQDDVN----KVSREMQLDGFSFFAIGVADADYSELVNIGSKPSERHVFFV- 1202
Query: 237 DGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKIN 296
D F A I ++ C A P G+ + GF+ V F
Sbjct: 1203 DDFDAFTKIEDELITFVCETASATCPLVFKDGD------KLAGFKMMEMFGLVEKEFSAI 1256
Query: 297 DSVTLNEKPFSVEDTYLLCPAPILKE 322
D V++ F+V Y L ++ +
Sbjct: 1257 DGVSMEPGTFNVYPCYRLHKDALVSQ 1282
>sp|P32018|CA1E_CHICK COLLAGEN ALPHA 1(XIV) CHAIN PRECURSOR (UNDULIN)
pir||S78476 collagen alpha 1(XIV) chain precursor, long form - chicken
emb|CAA50064.1| (X70793) collagen XIV [Gallus gallus]
Length = 1888
Score = 253 bits (640), Expect = 4e-66
Identities = 48/258 (18%), Positives = 89/258 (33%), Gaps = 27/258 (10%)
Query: 61 GQGGRREDGGPACYGGFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKFI--SPQLRMSFI 117
+G PA D+ ++D S S+ ++ + F+E L F S + R+
Sbjct: 144 PEGNLFTCKTPAIA---DIVILVDGSWSIGRFNFRLVRLFLENLVSAFNVGSEKTRVGLA 200
Query: 118 VFSTRGTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGYR- 174
+S L + + + + + LP GG+T E +
Sbjct: 201 QYSGDPRIEWHL--NAYGTKDAVLDAVRNLPYKGGNTLTGLALTYILENSFKPEAGARPG 258
Query: 175 TASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDF--NETQLARIADSKDHV 232
+ + I +TDG+ +D+ A RD G ++ +GVK+ NE + HV
Sbjct: 259 VSKIGILITDGKSQDDVI----PPAKNLRDAGIELFAIGVKNADINELKEIASEPDSTHV 314
Query: 233 FPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCS 292
+ V D F + I+ + + C + E + D
Sbjct: 315 YNVAD-FNFMNSIVEGLTRTVCSRVEEQEKEIKGTIAA-----SLGAPTDLVTSDITARG 368
Query: 293 FKINDSVTLNEKPFSVED 310
F+++ + P VE
Sbjct: 369 FRVSWT----HSPGKVEK 382
Score = 230 bits (581), Expect = 3e-59
Identities = 58/266 (21%), Positives = 105/266 (38%), Gaps = 23/266 (8%)
Query: 67 EDGGPACYG-GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF--ISPQ-LRMSFIVFST 121
C DL F++D S S+ ++N+I F+ I P +++ I FS
Sbjct: 1030 PPAKEVCKAAKADLVFLVDGSWSIGDDNFNKIISFLYSTVGALDKIGPDGTQVAIIQFSD 1089
Query: 122 RGTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGYR-TASV 178
T KL + + ++ L E + + GG+T + + A E ++ + V
Sbjct: 1090 DPRTEFKL--NAYKTKETLLEAIQQIAYKGGNTKTGKAIKHAREVLFTGEAGMRKGIPKV 1147
Query: 179 IIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQL--ARIADSKDHVFPVN 236
++ +TDG +D+ + + + G + +GV D + ++L S+ HVF V
Sbjct: 1148 LVVITDGRSQDDVN----KVSREMQLDGFSFFAIGVADADYSELVNIGSKPSERHVFFV- 1202
Query: 237 DGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKIN 296
D F A I ++ C A P G+ + GF+ V F
Sbjct: 1203 DDFDAFTKIEDELITFVCETASATCPLVFKDGD------KLAGFKMMEMFGLVEKEFSAI 1256
Query: 297 DSVTLNEKPFSVEDTYLLCPAPILKE 322
D V++ F+V Y L ++ +
Sbjct: 1257 DGVSMEPGTFNVYPCYRLHKDALVSQ 1282
>ref|XP_004249.1| collagen, type XII, alpha 1 [Homo sapiens]
Length = 2858
Score = 248 bits (626), Expect = 2e-64
Identities = 61/256 (23%), Positives = 105/256 (40%), Gaps = 34/256 (13%)
Query: 72 ACYGGFDL----YFILDKSGSVL-HHWNEIYYFVEQLAHKF-ISP-QLRMSFIVFSTRGT 124
C G D+ F++D S S+ ++ ++ F+E L F ISP ++++S + +S
Sbjct: 430 ECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPH 489
Query: 125 TLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGY-RTASVIIA 181
T L + + + E P GG T + E+I+ ++ V+I
Sbjct: 490 TEFTL--KKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMIL 547
Query: 182 LTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIA--DSKDHVFPVNDGF 239
+TDG+ + A + R+ ++ VGVKD ++L IA ++ HVF V D F
Sbjct: 548 ITDGKSSD----AFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVED-F 602
Query: 240 QALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARN---VDRVLCSFKIN 296
A Q I + + C+ I E ++ + ++ + FK N
Sbjct: 603 DAFQRISFELTQSICLRI-----------EQELAAIKKKAYVPPKDLSFSEVTSYGFKTN 651
Query: 297 DSVTLNEKPFSVEDTY 312
S E FS TY
Sbjct: 652 WSPAG-ENVFSYHITY 666
Score = 239 bits (603), Expect = 9e-62
Identities = 45/255 (17%), Positives = 99/255 (38%), Gaps = 32/255 (12%)
Query: 68 DGGPACYG--GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF-ISPQ-LRMSFIVFSTR 122
G C D+ ++D S S+ ++ + F+ ++ F I P+ ++++ +S
Sbjct: 1187 SSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGD 1246
Query: 123 GTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGY-RTASVI 179
T +L R ++ L + LP GG+T +Q + R +
Sbjct: 1247 PRTEWQLNAHR--DKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG 1304
Query: 180 IALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQL--ARIADSKDHVFPVND 237
+ +TDG+ +D+ E + + +D G ++ +G+K+ +E +L H + V D
Sbjct: 1305 VLITDGKSQDDV----EAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVAD 1360
Query: 238 GFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKIND 297
F++L I+ + C S + + +R SF+++
Sbjct: 1361 -FESLSRIVDDLTINLCN--------------SVKGPGDLEAPSNLVISERTHRSFRVSW 1405
Query: 298 SVTLNEKPFSVEDTY 312
+ ++ + Y
Sbjct: 1406 TPP-SDSVDRYKVEY 1419
Score = 198 bits (499), Expect = 1e-49
Identities = 50/234 (21%), Positives = 93/234 (39%), Gaps = 21/234 (8%)
Query: 78 DLYFILDKSGSVLHH-WNEIYYFVEQLAHKFI--SPQLRMSFIVFSTRGTTLMKLTEDRE 134
DL F++D S SV + + I F+ L F + R+ + +S+ T + ++
Sbjct: 140 DLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSD--TRTEFNLNQY 197
Query: 135 QIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGY-RTASVIIALTDGELHEDL 191
R L K +P GG+T + + + + E+ V I +TDG+ +++
Sbjct: 198 YQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEV 257
Query: 192 FFYSEREANRSRDLGAIVYCVGVK--DFNETQLARIADSKDHVFPVNDGFQALQGIIHSI 249
E A R++G V+ +G+K D E + S +HVF V F A+ I + I
Sbjct: 258 ----EIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNV-ANFDAIVDIQNEI 312
Query: 250 LKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINDSVTLNE 303
+ + C GE + ++ K+N + + +
Sbjct: 313 ISQVCS------GVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSP 360
Score = 171 bits (429), Expect = 2e-41
Identities = 52/266 (19%), Positives = 103/266 (38%), Gaps = 23/266 (8%)
Query: 67 EDGGPACYG-GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF--ISPQ-LRMSFIVFST 121
C G D+ F+ D S S+ ++N++ F+ F ISP +++SF+ +S
Sbjct: 2311 PPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSD 2370
Query: 122 RGTTLMKLTEDREQIRQGLEELQKVL--PGGDTYMHEGFERASEQIYYENRQGY-RTASV 178
+ KL + + + + GG+T + E++ V
Sbjct: 2371 EVKSEFKL--NTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKV 2428
Query: 179 IIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQL--ARIADSKDHVFPVN 236
++ +TDG +++ ++ A + G V+ VGV D + +L S+ HVF V
Sbjct: 2429 LVVVTDGRSQDEV----KKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIV- 2483
Query: 237 DGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKIN 296
D F++ + I +++ C ++ P G + GF+ + +F
Sbjct: 2484 DDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSP------GFKMLEAYNLTEKNFASV 2537
Query: 297 DSVTLNEKPFSVEDTYLLCPAPILKE 322
V+L F Y + + +
Sbjct: 2538 QGVSLESGSFPSYSAYRIQKNAFVNQ 2563
>ref|NP_004361.1| collagen, type XII, alpha 1 [Homo sapiens]
sp|Q99715|CA1C_HUMAN COLLAGEN ALPHA 1(XII) CHAIN PRECURSOR
gb|AAC51244.1| (U73778) collagen type XII alpha-1 [Homo sapiens]
Length = 3063
Score = 248 bits (626), Expect = 2e-64
Identities = 61/256 (23%), Positives = 105/256 (40%), Gaps = 34/256 (13%)
Query: 72 ACYGGFDL----YFILDKSGSVL-HHWNEIYYFVEQLAHKF-ISP-QLRMSFIVFSTRGT 124
C G D+ F++D S S+ ++ ++ F+E L F ISP ++++S + +S
Sbjct: 430 ECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPH 489
Query: 125 TLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGY-RTASVIIA 181
T L + + + E P GG T + E+I+ ++ V+I
Sbjct: 490 TEFTL--KKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMIL 547
Query: 182 LTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIA--DSKDHVFPVNDGF 239
+TDG+ + A + R+ ++ VGVKD ++L IA ++ HVF V D F
Sbjct: 548 ITDGKSSD----AFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVED-F 602
Query: 240 QALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARN---VDRVLCSFKIN 296
A Q I + + C+ I E ++ + ++ + FK N
Sbjct: 603 DAFQRISFELTQSICLRI-----------EQELAAIKKKAYVPPKDLSFSEVTSYGFKTN 651
Query: 297 DSVTLNEKPFSVEDTY 312
S E FS TY
Sbjct: 652 WSPAG-ENVFSYHITY 666
Score = 237 bits (599), Expect = 3e-61
Identities = 45/255 (17%), Positives = 99/255 (38%), Gaps = 32/255 (12%)
Query: 68 DGGPACYG--GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF-ISPQ-LRMSFIVFSTR 122
G C D+ ++D S S+ ++ + F+ ++ F I P+ ++++ +S
Sbjct: 1187 SSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGD 1246
Query: 123 GTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGY-RTASVI 179
T +L R ++ L + LP GG+T +Q + R +
Sbjct: 1247 PRTEWQLNAHR--DKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG 1304
Query: 180 IALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQL--ARIADSKDHVFPVND 237
+ +TDG+ +D+ E + + +D G ++ +G+K+ +E +L H + V D
Sbjct: 1305 VLITDGKSQDDV----EAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHDYNVAD 1360
Query: 238 GFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKIND 297
F++L I+ + C S + + +R SF+++
Sbjct: 1361 -FESLSRIVDDLTINLCN--------------SVKGPGDLEAPSNLVISERTHRSFRVSW 1405
Query: 298 SVTLNEKPFSVEDTY 312
+ ++ + Y
Sbjct: 1406 TPP-SDSVDRYKVEY 1419
Score = 198 bits (499), Expect = 1e-49
Identities = 50/234 (21%), Positives = 93/234 (39%), Gaps = 21/234 (8%)
Query: 78 DLYFILDKSGSVLHH-WNEIYYFVEQLAHKFI--SPQLRMSFIVFSTRGTTLMKLTEDRE 134
DL F++D S SV + + I F+ L F + R+ + +S+ T + ++
Sbjct: 140 DLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSD--TRTEFNLNQY 197
Query: 135 QIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGY-RTASVIIALTDGELHEDL 191
R L K +P GG+T + + + + E+ V I +TDG+ +++
Sbjct: 198 YQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEV 257
Query: 192 FFYSEREANRSRDLGAIVYCVGVK--DFNETQLARIADSKDHVFPVNDGFQALQGIIHSI 249
E A R++G V+ +G+K D E + S +HVF V F A+ I + I
Sbjct: 258 ----EIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNV-ANFDAIVDIQNEI 312
Query: 250 LKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINDSVTLNE 303
+ + C GE + ++ K+N + + +
Sbjct: 313 ISQVCS------GVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSP 360
Score = 171 bits (429), Expect = 2e-41
Identities = 52/266 (19%), Positives = 103/266 (38%), Gaps = 23/266 (8%)
Query: 67 EDGGPACYG-GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF--ISPQ-LRMSFIVFST 121
C G D+ F+ D S S+ ++N++ F+ F ISP +++SF+ +S
Sbjct: 2311 PPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSD 2370
Query: 122 RGTTLMKLTEDREQIRQGLEELQKVL--PGGDTYMHEGFERASEQIYYENRQGY-RTASV 178
+ KL + + + + GG+T + E++ V
Sbjct: 2371 EVKSEFKL--NTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKV 2428
Query: 179 IIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQL--ARIADSKDHVFPVN 236
++ +TDG +++ ++ A + G V+ VGV D + +L S+ HVF V
Sbjct: 2429 LVVVTDGRSQDEV----KKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIV- 2483
Query: 237 DGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKIN 296
D F++ + I +++ C ++ P G + GF+ + +F
Sbjct: 2484 DDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSP------GFKMLEAYNLTEKNFASV 2537
Query: 297 DSVTLNEKPFSVEDTYLLCPAPILKE 322
V+L F Y + + +
Sbjct: 2538 QGVSLESGSFPSYSAYRIQKNAFVNQ 2563
>gb|AAC01506.1| (U68139) type XII collagen [Homo sapiens]
Length = 517
Score = 247 bits (624), Expect = 3e-64
Identities = 61/255 (23%), Positives = 106/255 (40%), Gaps = 33/255 (12%)
Query: 72 ACYGGFDL---YFILDKSGSVL-HHWNEIYYFVEQLAHKF-ISP-QLRMSFIVFSTRGTT 125
C G D+ F++D S S+ ++ ++ F+E L F ISP ++++S + +S T
Sbjct: 132 ECSRGVDIKADMFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHT 191
Query: 126 LMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGY-RTASVIIAL 182
L + + + E P GG T + E+I+ ++ V+I +
Sbjct: 192 EFTL--KKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILI 249
Query: 183 TDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIA--DSKDHVFPVNDGFQ 240
TDG+ + A + R+ ++ VGVKD +++L IA ++ HVF V D F
Sbjct: 250 TDGKSSD----AFRDPAIKLRNSDVEIFAVGVKDAVDSELEAIASPPAETHVFTVED-FD 304
Query: 241 ALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARN---VDRVLCSFKIND 297
A Q I + + C+ I E ++ + ++ + FK N
Sbjct: 305 AFQRISFELTQSICLRI-----------EQELAAIKKKAYVPPKDLSFSEVTSYGFKTNW 353
Query: 298 SVTLNEKPFSVEDTY 312
S E FS TY
Sbjct: 354 SPAG-ENVFSYHITY 367
Score = 49.1 bits (115), Expect = 1e-04
Identities = 9/66 (13%), Positives = 20/66 (29%), Gaps = 6/66 (9%)
Query: 238 GFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKIND 297
F A+ I + I+ + C GE + ++ K+N
Sbjct: 3 NFDAIVDIQNEIISQVCS------GVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNW 56
Query: 298 SVTLNE 303
+ + +
Sbjct: 57 NPSPSP 62
>ref|NP_031756.1| procollagen, type XII, alpha 1 [Mus musculus]
sp|Q60847|CA1C_MOUSE COLLAGEN ALPHA 1(XII) CHAIN PRECURSOR
gb|AAA99719.1| (U25652) collagen type XII alpha-1 precursor [Mus musculus]
Length = 3067
Score = 243 bits (614), Expect = 4e-63
Identities = 65/253 (25%), Positives = 104/253 (40%), Gaps = 28/253 (11%)
Query: 72 ACYGGFDL----YFILDKSGSVLH-HWNEIYYFVEQLAHKF-ISP-QLRMSFIVFSTRGT 124
C G D+ F++D S S+ ++ ++ F+E LA F ISP ++++S + +S
Sbjct: 434 ECSRGVDIKADIVFLVDGSYSIGTANFVKVRAFLEVLAKSFEISPNRVQISLVQYSRDPH 493
Query: 125 TLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGY-RTASVIIA 181
T L E + + + P GG T + E+I+ N+ V+I
Sbjct: 494 TEFTLKEFNR--VEDIIKAINTFPYRGGSTNTGKAMTYVREKIFVPNKGSRSNVPKVMIL 551
Query: 182 LTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIA--DSKDHVFPVNDGF 239
+TDGE + A + R+ ++ VGVKD ++L IA ++ HVF V D F
Sbjct: 552 ITDGESSD----AFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVED-F 606
Query: 240 QALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINDSV 299
A Q I + + C+ I E + I + R SFK S
Sbjct: 607 DAFQRISFVLTQSICLRI-EQELAAIKKKAYV-------PPKDLRFTQVTANSFKAEWSP 658
Query: 300 TLNEKPFSVEDTY 312
+ FS TY
Sbjct: 659 PG-DNVFSYHVTY 670
Score = 236 bits (597), Expect = 4e-61
Identities = 45/257 (17%), Positives = 99/257 (38%), Gaps = 32/257 (12%)
Query: 66 REDGGPACYG--GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF-ISPQ-LRMSFIVFS 120
G C D+ ++D S S+ ++ + F+ ++ F I P+ ++++ +S
Sbjct: 1189 FLSSGMDCLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYS 1248
Query: 121 TRGTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGY-RTAS 177
T +L R ++ L + LP GG+T +Q + R
Sbjct: 1249 GDPRTEWQLNAHR--DKKSLLQAVANLPNKGGNTLTGMALNFIRQQSFKTQAGMRPRARK 1306
Query: 178 VIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQL--ARIADSKDHVFPV 235
+ + +TDG+ +D+ E + + +D G ++ +G+K+ +E +L H + V
Sbjct: 1307 IGVLITDGKSQDDV----EAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNV 1362
Query: 236 NDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKI 295
D F++L I+ + C S + + +R SF++
Sbjct: 1363 AD-FESLSKIVDDLTINLCN--------------SVKGPGDLEAPTNLVISERTHRSFRV 1407
Query: 296 NDSVTLNEKPFSVEDTY 312
+ + ++ + Y
Sbjct: 1408 SWTPP-SDSVDRYKVEY 1423
Score = 193 bits (486), Expect = 4e-48
Identities = 48/233 (20%), Positives = 92/233 (38%), Gaps = 21/233 (9%)
Query: 78 DLYFILDKSGSVLHH-WNEIYYFVEQLAHKFI--SPQLRMSFIVFSTRGTTLMKLTEDRE 134
DL F++D S SV + + I F+ L F + R+ + +S+ T + ++
Sbjct: 140 DLVFLVDGSWSVGRNNFKYILDFIVALVSAFDIGEEKTRVGVVQYSSD--TRTEFNLNQY 197
Query: 135 QIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGY-RTASVIIALTDGELHEDL 191
R+ L K +P GG+T + + + + E+ V I +TDG+ +++
Sbjct: 198 YRREDLLAAVKKIPYKGGNTMTGDAIDYLVKNTFTESAGSRAGFPKVGIIITDGKSQDEV 257
Query: 192 FFYSEREANRSRDLGAIVYCVGVK--DFNETQLARIADSKDHVFPVNDGFQALQGIIHSI 249
E A R++G V+ +G+K D E + S +HVF V F A+ I + I
Sbjct: 258 ----EIPARELRNIGVEVFSLGIKAADAKELKQIASTPSLNHVFNV-ANFDAIVDIQNEI 312
Query: 250 LKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINDSVTLN 302
+ + C GE + + +++ + +
Sbjct: 313 ISQVCS------GVDEQLGELVSGEEVIEPPSNLVVTELSSKYIRLSWDPSPS 359
Score = 163 bits (410), Expect = 4e-39
Identities = 50/265 (18%), Positives = 100/265 (36%), Gaps = 22/265 (8%)
Query: 67 EDGGPACYG-GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKFISPQ---LRMSFIVFST 121
C G D+ F+ D S S+ ++N++ F+ F +++SF+ +S
Sbjct: 2317 PPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGAFDEVNPAGIQVSFVQYSD 2376
Query: 122 RGTTLMKLTEDREQIRQGLEELQKVL--PGGDTYMHEGFERASEQIYYENRQGYRTASVI 179
+ KL + + + + GG+T + E++ + V+
Sbjct: 2377 EVKSEFKL--NTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVRVL 2434
Query: 180 IALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQL--ARIADSKDHVFPVND 237
+TDG +++ ++ A + G V+ VGV D + +L S+ HVF V D
Sbjct: 2435 GVVTDGRSQDEV----KKAAFVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIV-D 2489
Query: 238 GFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKIND 297
F++ + I +++ C ++ P G + GF+ + +F
Sbjct: 2490 DFESFEKIEDNLITFVCETATSSCPLIYQDGYTSP------GFKMLEAYNLTEKNFASVQ 2543
Query: 298 SVTLNEKPFSVEDTYLLCPAPILKE 322
V+L F Y L + +
Sbjct: 2544 GVSLESGSFPDSSAYRLQKNAFINQ 2568
>emb|CAB71222.1| (AL096771) dJ238D15.1 (collagen, type XII, alpha 1) [Homo sapiens]
Length = 2003
Score = 239 bits (603), Expect = 9e-62
Identities = 45/255 (17%), Positives = 99/255 (38%), Gaps = 32/255 (12%)
Query: 68 DGGPACYG--GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF-ISPQ-LRMSFIVFSTR 122
G C D+ ++D S S+ ++ + F+ ++ F I P+ ++++ +S
Sbjct: 283 SSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGD 342
Query: 123 GTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGY-RTASVI 179
T +L R ++ L + LP GG+T +Q + R +
Sbjct: 343 PRTEWQLNAHR--DKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG 400
Query: 180 IALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQL--ARIADSKDHVFPVND 237
+ +TDG+ +D+ E + + +D G ++ +G+K+ +E +L H + V D
Sbjct: 401 VLITDGKSQDDV----EAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVAD 456
Query: 238 GFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKIND 297
F++L I+ + C S + + +R SF+++
Sbjct: 457 -FESLSRIVDDLTINLCN--------------SVKGPGDLEAPSNLVISERTHRSFRVSW 501
Query: 298 SVTLNEKPFSVEDTY 312
+ ++ + Y
Sbjct: 502 TPP-SDSVDRYKVEY 515
Score = 137 bits (341), Expect = 5e-31
Identities = 55/300 (18%), Positives = 97/300 (32%), Gaps = 70/300 (23%)
Query: 67 EDGGPACYG-GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF--ISPQ-LRMSFIVFST 121
C G D+ F+ D S S+ ++N++ F+ F ISP +++SF+ +S
Sbjct: 1419 PPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSD 1478
Query: 122 RGTTLMKLTEDREQIRQGLEELQKVL--PGGDTYM------------------------- 154
+ KL + + + + GG+T
Sbjct: 1479 EVKSEFKL--NTYNDKALALGALQNIRYRGGNTRTDSYQLGVTNGIWVVFTEVTLKFSMP 1536
Query: 155 ---HEGFERASEQIYYENRQGY-RTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVY 210
+ E++ V++ +TDG V+
Sbjct: 1537 HSVGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGFS---------------------VF 1575
Query: 211 CVGVKDFNETQL--ARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAG 268
VGV D + +L S+ HVF V D F++ + I +++ C A ++
Sbjct: 1576 VVGVADVDYNELANIASKPSERHVFIV-DDFESFEKIEDNLITFVCET---ATSTSSKTL 1631
Query: 269 ESFQVVVRGNGFRHARNVDRVLC----SFKINDSVTLNEKPFSVEDTYLLCPAPILKEVG 324
F RG + + V SF V ++ D Y + I KE G
Sbjct: 1632 SFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDI-KEAG 1690
>gb|AAB03226.1| (U59801) integrin alpha-M [Rattus norvegicus]
Length = 205
Score = 238 bits (602), Expect = 1e-61
Identities = 43/196 (21%), Positives = 72/196 (35%), Gaps = 16/196 (8%)
Query: 100 VEQLAHKFISPQLRMSFIVFSTRGTTLMKLT-EDREQIRQGLEELQKVLPGGDTYMHEGF 158
V + +F + S + +S T R + + L G T G
Sbjct: 1 VSTVMEQFQKSKTLFSLMQYSDEFRTHFTFNXFKRNPDPKSHVRPIRQL-NGRTKTASGI 59
Query: 159 ERASEQIYYENRQGYRT-ASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDF 217
+ +++ + A +++ +TDGE D Y E + + G I Y +GV +
Sbjct: 60 RKVVRELFQKINGARDNAAKILVVITDGEKFGDPLNY-EDVIPEAEEAGIIRYVIGVXNA 118
Query: 218 N-------ETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGES 270
E + DHVF V D F+AL I + + +K I A E + + S
Sbjct: 119 FHKPQSRRELDTIASKPAGDHVFQV-DNFEALNTIRNQLQEK----IFAIEGTQTGSTSS 173
Query: 271 FQVVVRGNGFRHARNV 286
F+ + GF A
Sbjct: 174 FEHEMSQEGFSAAITS 189
>emb|CAA72402.1| (Y11710) collagen type XIV [Homo sapiens]
Length = 755
Score = 237 bits (598), Expect = 3e-61
Identities = 53/254 (20%), Positives = 100/254 (38%), Gaps = 22/254 (8%)
Query: 78 DLYFILDKSGSVL-HHWNEIYYFVEQLAHKFIS---PQLRMSFIVFSTRGTTLMKLTEDR 133
DL F++D S S+ ++N+I F+ +++ + F+ T KL +
Sbjct: 7 DLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEFKL--NA 64
Query: 134 EQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGYR-TASVIIALTDGELHED 190
+ ++ L + K + GG+T + + + ++ R VI+ +TDG +D
Sbjct: 65 YKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIPKVIVVITDGRSQDD 124
Query: 191 LFFYSEREANRSRDLGAIVYCVGVKDFNETQL--ARIADSKDHVFPVNDGFQALQGIIHS 248
+ S + G ++ +GV D + ++L S HVF V D F A + I
Sbjct: 125 VNKISR----EMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFV-DDFDAFKKIEDE 179
Query: 249 ILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSV 308
++ C A P G + GF+ V F + V++ F+V
Sbjct: 180 LITFVCETASATCPVVHKDG------IDLAGFKMMEMFGLVEKDFSSVEGVSMEPGTFNV 233
Query: 309 EDTYLLCPAPILKE 322
Y L ++ +
Sbjct: 234 FPCYQLHKDALVSQ 247
>sp|P13944|CA1C_CHICK COLLAGEN ALPHA 1(XII) CHAIN PRECURSOR (FIBROCHIMERIN)
pir||A40020 collagen alpha 1(XII) chain precursor - chicken
dbj|BAA00701.1| (D00824) alpha 1 chain of type XII collagen [Gallus gallus]
emb|CAA43358.1| (X61024) collagen type XII alpha 1 chain [Gallus gallus]
Length = 3124
Score = 237 bits (598), Expect = 3e-61
Identities = 63/258 (24%), Positives = 113/258 (43%), Gaps = 38/258 (14%)
Query: 72 ACYGGFDL----YFILDKSGSVL-HHWNEIYYFVEQLAHKF-ISP-QLRMSFIVFSTRGT 124
C G D+ F++D S S+ ++ ++ F+E L F ISP ++++S + +S
Sbjct: 429 ECSRGVDVKADVVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPRKVQISLVQYSRD-- 486
Query: 125 TLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGY-RTASVIIA 181
M+ + +R + + + P GG T + E+++ ++ V+I
Sbjct: 487 PHMEFSLNRYNRVKDIIQAINTFPYRGGSTNTGKAMTYVREKVFVTSKGSRPNVPRVMIL 546
Query: 182 LTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIA--DSKDHVFPVNDGF 239
+TDG+ + + A + RD ++ VGVKD T+L IA ++ HV+ V D F
Sbjct: 547 ITDGKSSD----AFKEPAIKLRDADVEIFAVGVKDAVRTELEAIASPPAETHVYTVED-F 601
Query: 240 QALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARN---VDRVLCSFKIN 296
A Q I + + C+ I E +R + A+N D SFK++
Sbjct: 602 DAFQRISFELTQSVCLRI-----------EQELAAIRKKSYVPAKNMVFSDVTSDSFKVS 650
Query: 297 DSVTLNEKPFSVEDTYLL 314
S +E E +YL+
Sbjct: 651 WSAAGSE-----EKSYLI 663
Score = 218 bits (549), Expect = 2e-55
Identities = 45/257 (17%), Positives = 90/257 (34%), Gaps = 32/257 (12%)
Query: 66 REDGGPACYG--GFDLYFILDKSGSVL-HHWNEIYYFVEQLAHKF-ISP-QLRMSFIVFS 120
G C D+ ++D S S+ ++ + F+ ++ F I P ++++ +S
Sbjct: 1185 FLSRGLECRTRAEADIVLLVDGSWSIGRPNFKTVRNFISRIVEVFDIGPDKVQIGLAQYS 1244
Query: 121 TRGTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGY-RTAS 177
T + + ++ L + LP GG+T + + + + R
Sbjct: 1245 GDPRTEW--NLNAYRTKEALLDAVTNLPYKGGNTLTGMALDFILKNNFKQEAGLRPRARK 1302
Query: 178 VIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQL--ARIADSKDHVFPV 235
+ + +TDG+ +D+ + R RD G +Y +G+K+ +E +L H + V
Sbjct: 1303 IGVLITDGKSQDDV----VTPSRRLRDEGVELYAIGIKNADENELKQIATDPDDIHAYNV 1358
Query: 236 NDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKI 295
D F L I + C S + + + SF++
Sbjct: 1359 AD-FSFLASIGEDVTTNLCN--------------SVKGPGDLPPPSNLVISEVTPHSFRL 1403
Query: 296 NDSVTLNEKPFSVEDTY 312
S E Y
Sbjct: 1404 RWSPPP-ESVDRYRVEY 1419
Score = 193 bits (487), Expect = 3e-48
Identities = 53/254 (20%), Positives = 95/254 (36%), Gaps = 23/254 (9%)
Query: 59 CAGQGGRREDGGPACY--GGFDLYFILDKSGSVLHH-WNEIYYFVEQLAHKFI--SPQLR 113
+ + E C DL F++D S SV + + I F+ L F + R
Sbjct: 118 GIPEEKKVEAQIQKCSISAMTDLVFLVDGSWSVGRNNFRYILDFMVALVSAFDIGEEKTR 177
Query: 114 MSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQ 171
+ + +S+ T + ++ R L + K +P GG+T E + + + E+
Sbjct: 178 VGVVQYSSDTRT--EFNLNQYFRRSDLLDAIKRIPYKGGNTMTGEAIDYLVKNTFTESAG 235
Query: 172 GYR-TASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVK--DFNETQLARIADS 228
+ V I +TDG+ +++ E A R++G V+ +G+K D E +L S
Sbjct: 236 ARKGFPKVAIVITDGKAQDEV----EIPARELRNIGVEVFSLGIKAADAKELKLIASQPS 291
Query: 229 KDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDR 288
HVF V F + I + I+ + C GE +
Sbjct: 292 LKHVFNV-ANFDGIVDIQNEIILQVCS------GVDEQLGELVSGEEVVEPASNLVATQI 344
Query: 289 VLCSFKINDSVTLN 302
S +I + +
Sbjct: 345 SSKSVRITWDPSTS 358
Score = 179 bits (450), Expect = 7e-44
Identities = 51/252 (20%), Positives = 97/252 (38%), Gaps = 18/252 (7%)
Query: 78 DLYFILDKSGSVLH-HWNEIYYFVEQLAHKF--ISPQ-LRMSFIVFSTRGTTLMKLTEDR 133
D+ F+ D S S+ ++N++ FV F I+P +++S + +S + KL
Sbjct: 2327 DIVFLTDASWSIGDDNFNKVVKFVFNTVGAFDLINPAGIQVSLVQYSDEAQSEFKLNTFD 2386
Query: 134 EQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYR-TASVIIALTDGELHEDLF 192
++ + GG+T + E++ R V++ +TDG +++
Sbjct: 2387 DKAQALGALQNVQYRGGNTRTGKALTFIKEKVLTWESGMRRGVPKVLVVVTDGRSQDEV- 2445
Query: 193 FYSEREANRSRDLGAIVYCVGVKDFNETQL--ARIADSKDHVFPVNDGFQALQGIIHSIL 250
+ A + G V+ VGV D + +L S+ HVF V D F A + I +++
Sbjct: 2446 ---RKAATVIQHSGFSVFVVGVADVDYNELAKIASKPSERHVFIV-DDFDAFEKIQDNLV 2501
Query: 251 KKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVED 310
C ++ C + GF+ + + F V+L F
Sbjct: 2502 TFVCET-----ATSTCPLIYLEGYTS-PGFKMLESYNLTEKHFASVQGVSLESGSFPSYV 2555
Query: 311 TYLLCPAPILKE 322
Y L + +
Sbjct: 2556 AYRLHKNAFVSQ 2567
>sp|Q91145|CA1C_NOTVI COLLAGEN ALPHA 1(XII) CHAIN
pir||I51027 type XII collagen alpha-1 chain - eastern newt (fragment)
gb|AAA80217.1| (U19494) type XII collagen alpha-1 chain [Notophthalmus
viridescens]
Length = 929
Score = 236 bits (595), Expect = 7e-61
Identities = 47/254 (18%), Positives = 96/254 (37%), Gaps = 32/254 (12%)
Query: 67 EDGGPACYG--GFDLYFILDKSGSVL-HHWNEIYYFVEQLAHKFI--SPQLRMSFIVFST 121
G C D+ ++D S S+ ++ + F+ ++ F S +++++ +S
Sbjct: 620 PSSGLDCTTKAQADIVLLVDGSWSIGRPNFKIVRNFISRVVEVFDIGSDRVQIAVSQYSG 679
Query: 122 RGTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGYRTA-SV 178
T +L + ++ L + LP GG+T + E + A +
Sbjct: 680 DPRTEWQLNTHK--TKKSLMDAVANLPYKGGNTNTGSALKFILENNFRPGVGMREKARKI 737
Query: 179 IIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQL--ARIADSKDHVFPVN 236
I LTDG+ +D+ + R D G +Y VG+K+ +E +L + +++ V
Sbjct: 738 AILLTDGKSQDDI----VAPSKRYADEGIELYAVGIKNADENELKEIASDPDELYMYNVA 793
Query: 237 DGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKIN 296
D F L I++ + + C + N + + SF++
Sbjct: 794 D-FSLLTNIVNDLTENVCNSVKGPGG--------------LNPPSNLVTSEPTPRSFRVT 838
Query: 297 DSVT-LNEKPFSVE 309
+ + F VE
Sbjct: 839 WVPPSQSVERFKVE 852
Score = 77.9 bits (189), Expect = 3e-13
Identities = 23/100 (23%), Positives = 37/100 (37%), Gaps = 11/100 (11%)
Query: 206 GAIVYCVGVKDFNETQLARIA--DSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPS 263
++ VGVKD ++L IA + HV+ V D F A Q I + + + I S
Sbjct: 1 DVEIFAVGVKDAVRSELEAIATPPTATHVYTVED-FDAFQRISFELTQSIWLRIEQELKS 59
Query: 264 TICAGESFQVVVRGNGFRHARNVDRVLCSFKINDSVTLNE 303
V R + SF+++ S +
Sbjct: 60 IK--------VKSLTPPRDLSFAEVTSSSFRVSWSPAAED 91
>ref|NP_060623.1| hypothetical protein FLJ10601 [Homo sapiens]
dbj|BAA91707.1| (AK001463) unnamed protein product [Homo sapiens]
Length = 218
Score = 232 bits (586), Expect = 8e-60
Identities = 189/194 (97%), Positives = 191/194 (98%)
Query: 114 MSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGY 173
MSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGY
Sbjct: 1 MSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGY 60
Query: 174 RTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVF 233
RTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVF
Sbjct: 61 RTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVF 120
Query: 234 PVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSF 293
PVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSF
Sbjct: 121 PVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSF 180
Query: 294 KINDSVTLNEKPFS 307
KINDSVTL++ S
Sbjct: 181 KINDSVTLSKSLQS 194
>pdb|1BHQ|1 Chain 1, Mac-1 I Domain Cadmium Complex
pdb|1BHQ|2 Chain 2, Mac-1 I Domain Cadmium Complex
pdb|1BHO|1 Chain 1, Mac-1 I Domain Magnesium Complex
pdb|1BHO|2 Chain 2, Mac-1 I Domain Magnesium Complex
pdb|1IDN|1 Chain 1, Mac-1 I Domain Metal Free
pdb|1IDN|2 Chain 2, Mac-1 I Domain Metal Free
Length = 190
Score = 230 bits (581), Expect = 3e-59
Identities = 44/194 (22%), Positives = 75/194 (37%), Gaps = 15/194 (7%)
Query: 78 DLYFILDKSGSVLHH-WNEIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQI 136
D+ F++D SGS++ H + + FV + + + S + +S E +
Sbjct: 3 DIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLFSLMQYSEEFRIHFTFKEFQNNP 62
Query: 137 RQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTA-SVIIALTDGELHEDLFFYS 195
G T+ G + +++ + A +++ +TDGE D Y
Sbjct: 63 NPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPLGY- 121
Query: 196 EREANRSRDLGAIVYCVGVKDFN-------ETQLARIADSKDHVFPVNDGFQALQGIIHS 248
E + G I Y +GV D E +DHVF VN F+AL+ I +
Sbjct: 122 EDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVN-NFEALKTIQNQ 180
Query: 249 ILKKSCIEILAAEP 262
+ +K I A E
Sbjct: 181 LREK----IFAIEG 190
>dbj|BAA23160.1| (AB000470) alpha1 integrin [Gallus gallus]
Length = 1171
Score = 230 bits (581), Expect = 3e-59
Identities = 42/258 (16%), Positives = 85/258 (32%), Gaps = 30/258 (11%)
Query: 50 ALTATLVLICAGQGG--RREDGGPACYGGFDLYFILDKSGSVLHHWNEIYYFVEQLAHKF 107
T + + C D+ +LD S S+ W + F+ L
Sbjct: 132 YTTGVCSNVSSTFETVKAVAPSVQECKTQLDIVIVLDGSNSIYP-WESVTAFLNSLLRNM 190
Query: 108 -ISPQ-LRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLP---GGDTYMHEGFERAS 162
I PQ ++ + + + + + + + + G T G + A
Sbjct: 191 DIGPQQTQVGIVQYGQTVVH--EFYLNTYSTTEEVMDAALRIRQRGGTQTMTALGIDTAR 248
Query: 163 EQIYYENRQGYR-TASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKD----- 216
E+ + E R V++ +TDGE H++ + ++ D + + +
Sbjct: 249 EEAFTEAHGARRGVQKVMVIVTDGESHDNY--RLQEVIDKCEDENIQRFAIAILGSYSRG 306
Query: 217 -------FNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGE 269
E + ++ H F V+D + I++ I A E +T
Sbjct: 307 NLSTEKFVEEIKSIASKPTEKHFFNVSDELALVT-----IVEALGERIFALEATTDQQAA 361
Query: 270 SFQVVVRGNGFRHARNVD 287
SF++ + GF + D
Sbjct: 362 SFEMEMSQAGFSAHYSQD 379
>sp|Q90615|ITA1_CHICK INTEGRIN ALPHA-1 (LAMININ AND COLLAGEN RECEPTOR) (VLA-1) (CD49A)
gb|AAA59067.1| (U10114) alpha 1 integrin [Gallus gallus]
Length = 285
Score = 230 bits (581), Expect = 3e-59
Identities = 42/258 (16%), Positives = 85/258 (32%), Gaps = 30/258 (11%)
Query: 50 ALTATLVLICAGQGG--RREDGGPACYGGFDLYFILDKSGSVLHHWNEIYYFVEQLAHKF 107
T + + C D+ +LD S S+ W + F+ L
Sbjct: 33 YTTGVCSNVSSTFETVKAVAPSVQECKTQLDIVIVLDGSNSIYP-WESVTAFLNSLLRNM 91
Query: 108 -ISPQ-LRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLP---GGDTYMHEGFERAS 162
I PQ ++ + + + + + + + + G T G + A
Sbjct: 92 DIGPQQTQVGIVQYGQTVVH--EFYLNTYSTTEEVMDAALRIRQRGGTQTMTALGIDTAR 149
Query: 163 EQIYYENRQGYR-TASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKD----- 216
E+ + E R V++ +TDGE H++ + ++ D + + +
Sbjct: 150 EEAFTEAHGARRGVQKVMVIVTDGESHDNY--RLQEVIDKCEDENIQRFAIAILGSYSRG 207
Query: 217 -------FNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGE 269
E + ++ H F V+D + I++ I A E +T
Sbjct: 208 NLSTEKFVEEIKSIASKPTEKHFFNVSDELALVT-----IVEALGERIFALEATTDQQAA 262
Query: 270 SFQVVVRGNGFRHARNVD 287
SF++ + GF + D
Sbjct: 263 SFEMEMSQAGFSAHYSQD 280
>sp|P18614|ITA1_RAT INTEGRIN ALPHA-1 PRECURSOR (LAMININ AND COLLAGEN RECEPTOR) (VLA-1)
(CD49A)
pir||A35854 integrin alpha-1 chain precursor - rat
emb|CAA36384.1| (X52140) precursor polypeptide (AA -28 to 1152) [Rattus norvegicus]
Length = 1180
Score = 230 bits (581), Expect = 3e-59
Identities = 42/235 (17%), Positives = 85/235 (35%), Gaps = 28/235 (11%)
Query: 71 PACYGGFDLYFILDKSGSVLHHWNEIYYFVEQLAHKF-ISPQ-LRMSFIVFSTRGTTLMK 128
C D+ +LD S S+ W + F+ L + I P+ ++ + + T +
Sbjct: 165 QECSTQLDIVIVLDGSNSIYP-WESVIAFLNDLLKRMDIGPKQTQVGIVQYGENVTH--E 221
Query: 129 LTEDREQIRQGLEELQKVLP--GGD-TYMHEGFERASEQIYYENRQGYR-TASVIIALTD 184
++ + + + GG T G + A ++ + E R R V++ +TD
Sbjct: 222 FNLNKYSSTEEVLVAANKIGRQGGLQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTD 281
Query: 185 GELHEDLFFYSEREANRSRDLGAIVYCVGVKD------------FNETQLARIADSKDHV 232
GE H++ ++ D + + + E + ++ H
Sbjct: 282 GESHDNY--RLKQVIQDCEDENIQRFSIAILGHYNRGNLSTEKFVEEIKSIASEPTEKHF 339
Query: 233 FPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVD 287
F V+D + I+K I A E + + SF++ + GF + D
Sbjct: 340 FNVSDELALVT-----IVKALGERIFALEATADQSAASFEMEMSQTGFSAHYSQD 389
>pdb|1JLM| I-Domain From Integrin Cr3, Mn2+ Bound
Length = 192
Score = 230 bits (580), Expect = 4e-59
Identities = 42/192 (21%), Positives = 73/192 (37%), Gaps = 12/192 (6%)
Query: 72 ACYGG-FDLYFILDKSGSVLHH-WNEIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKL 129
C D+ F++D SGS++ H + + FV + + + S + +S
Sbjct: 1 GCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLFSLMQYSEEFRIHFTF 60
Query: 130 TEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTA-SVIIALTDGELH 188
E + G T+ G + +++ + A +++ +TDGE
Sbjct: 61 KEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKF 120
Query: 189 EDLFFYSEREANRSRDLGAIVYCVGVKDFN-------ETQLARIADSKDHVFPVNDGFQA 241
D Y E + G I Y +GV D E +DHVF VN F+A
Sbjct: 121 GDPLGY-EDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVN-NFEA 178
Query: 242 LQGIIHSILKKS 253
L+ I + + +K
Sbjct: 179 LKTIQNQLREKI 190
>sp|P56199|ITA1_HUMAN INTEGRIN ALPHA-1 (LAMININ AND COLLAGEN RECEPTOR) (VLA-1) (CD49A)
pir||A45226 integrin alpha 1 subunit - human (fragment)
Length = 1151
Score = 229 bits (578), Expect = 7e-59
Identities = 44/235 (18%), Positives = 87/235 (36%), Gaps = 28/235 (11%)
Query: 71 PACYGGFDLYFILDKSGSVLHHWNEIYYFVEQLAHKF-ISPQ-LRMSFIVFSTRGTTLMK 128
C D+ +LD S S+ W+ + F+ L + I P+ ++ + + T +
Sbjct: 137 QECSTQLDIVIVLDGSNSIYP-WDSVTAFLNDLLKRMDIGPKQTQVGIVQYGENVTH--E 193
Query: 129 LTEDREQIRQGLEELQK--VLPGGD-TYMHEGFERASEQIYYENRQGYR-TASVIIALTD 184
++ + + K V GG T G + A ++ + E R R V++ +TD
Sbjct: 194 FNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTD 253
Query: 185 GELHEDLFFYSEREANRSRDLGAIVYCVGVKD------------FNETQLARIADSKDHV 232
GE H++ ++ D + + + E + ++ H
Sbjct: 254 GESHDN--HRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHF 311
Query: 233 FPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVD 287
F V+D + I+K I A E + + SF++ + GF + D
Sbjct: 312 FNVSDELALVT-----IVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQD 361
>pdb|1IDO| I-Domain From Integrin Cr3, Mg2+ Bound
Length = 192
Score = 228 bits (576), Expect = 1e-58
Identities = 42/194 (21%), Positives = 73/194 (36%), Gaps = 15/194 (7%)
Query: 72 ACYGGF----DLYFILDKSGSVLHH-WNEIYYFVEQLAHKFISPQLRMSFIVFSTRGTTL 126
C D+ F++D SGS++ H + + FV + + + S + +S
Sbjct: 1 GCPQEIFADSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLFSLMQYSEEFRIH 60
Query: 127 MKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTA-SVIIALTDG 185
E + G T+ G + +++ + A +++ +TDG
Sbjct: 61 FTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDG 120
Query: 186 ELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN-------ETQLARIADSKDHVFPVNDG 238
E D Y E + G I Y +GV D E +DHVF VN
Sbjct: 121 EKFGDPLGY-EDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVN-N 178
Query: 239 FQALQGIIHSILKK 252
F+AL+ I + + +K
Sbjct: 179 FEALKTIQNQLREK 192
>pir||A55348 integrin alpha-1 - chicken (fragment)
Length = 272
Score = 227 bits (573), Expect = 3e-58
Identities = 41/256 (16%), Positives = 84/256 (32%), Gaps = 30/256 (11%)
Query: 50 ALTATLVLICAGQGG--RREDGGPACYGGFDLYFILDKSGSVLHHWNEIYYFVEQLAHKF 107
T + + C D+ +LD S S+ W + F+ L
Sbjct: 27 YTTGVCSNVSSTFETVKAVAPSVQECKTQLDIVIVLDGSNSIYP-WESVTAFLNSLLRNM 85
Query: 108 -ISPQ-LRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLP---GGDTYMHEGFERAS 162
I PQ ++ + + + + + + + + G T G + A
Sbjct: 86 DIGPQQTQVGIVQYGQTVVH--EFYLNTYSTTEEVMDAALRIRQRGGTQTMTALGIDTAR 143
Query: 163 EQIYYENRQGYR-TASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKD----- 216
E+ + E R V++ +TDGE H++ + ++ D + + +
Sbjct: 144 EEAFTEAHGARRGVQKVMVIVTDGESHDNY--RLQEVIDKCEDENIQRFAIAILGSYSRG 201
Query: 217 -------FNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGE 269
E + ++ H F V+D + I++ I A E +T
Sbjct: 202 NLSTEKFVEEIKSIASKPTEKHFFNVSDELALVT-----IVEALGERIFALEATTDQQAA 256
Query: 270 SFQVVVRGNGFRHARN 285
SF++ + GF +
Sbjct: 257 SFEMEMSQAGFSAHYS 272
>emb|CAB65984.1| (AL080250) dJ234P15.1 (collagen, type XII, alpha 1) [Homo sapiens]
Length = 660
Score = 220 bits (556), Expect = 3e-56
Identities = 51/198 (25%), Positives = 89/198 (44%), Gaps = 19/198 (9%)
Query: 72 ACYGGFDL----YFILDKSGSVL-HHWNEIYYFVEQLAHKF-ISP-QLRMSFIVFSTRGT 124
C G D+ F++D S S+ ++ ++ F+E L F ISP ++++S + +S
Sbjct: 459 ECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPH 518
Query: 125 TLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGY-RTASVIIA 181
T L + + + E P GG T + E+I+ ++ V+I
Sbjct: 519 TEFTL--KKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMIL 576
Query: 182 LTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIA--DSKDHVFPVNDGF 239
+TDG+ + A + R+ ++ VGVKD ++L IA ++ HVF V D F
Sbjct: 577 ITDGKSSD----AFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVED-F 631
Query: 240 QALQGIIHSILKKSCIEI 257
A Q I + + C+ I
Sbjct: 632 DAFQRISFELTQSICLRI 649
Score = 184 bits (463), Expect = 2e-45
Identities = 50/263 (19%), Positives = 92/263 (34%), Gaps = 50/263 (19%)
Query: 78 DLYFILDKSGSVLHH-WNEIYYFVEQLAHKFI--SPQLRMSFIVFSTRGTTLMKLTEDRE 134
DL F++D S SV + + I F+ L F + R+ + +S+ T + ++
Sbjct: 140 DLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSD--TRTEFNLNQY 197
Query: 135 QIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGY-RTASVIIALTDGELHEDL 191
R L K +P GG+T + + + + E+ V I +TDG+ +++
Sbjct: 198 YQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEV 257
Query: 192 FFYSEREANRSRDLGAIVYCVGVK-------------------------------DFNET 220
E A R++G V+ + VK D E
Sbjct: 258 ----EIPARELRNVGVEVFSLVVKDGENEELLQVSWHISHFNMSLSFCFEGIKAADAKEL 313
Query: 221 QLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGF 280
+ S +HVF V F A+ I + I+ + C GE
Sbjct: 314 KQIASTPSLNHVFNV-ANFDAIVDIQNEIISQVCS------GVDEQLGELVSGEEVVEPP 366
Query: 281 RHARNVDRVLCSFKINDSVTLNE 303
+ ++ K+N + + +
Sbjct: 367 SNLIAMEVSSKYVKLNWNPSPSP 389
>ref|NP_038620.1| matrilin 4 [Mus musculus]
emb|CAA06889.1| (AJ006140) matrilin-4 precursor [Mus musculus]
Length = 624
Score = 215 bits (542), Expect = 1e-54
Identities = 51/229 (22%), Positives = 82/229 (35%), Gaps = 17/229 (7%)
Query: 50 ALTATLVLICAGQGGRREDGGPACYGG-FDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF 107
+ L+L + + GP CY G DL F++D S SV + + F+ L
Sbjct: 7 WPLSLLLLFLQSWETQLQSAGPRCYNGPLDLVFMIDSSRSVRPFEFETMRQFLVGLLRSL 66
Query: 108 IS--PQLRMSFIVFSTRGTTLMKLTED-REQIRQGLEELQKVLPGGDTYMHEGFERASEQ 164
R+ I +S++ ++ L R + + L G T + A
Sbjct: 67 DVGLNATRVGVIQYSSQVQSVFPLGAFSRREDMERAIRAVVPLAQG-TMTGLAIQYAMNV 125
Query: 165 IYYENRQGY----RTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNET 220
+ E R V++ +TDG A ++R G +Y VGV+ +
Sbjct: 126 AFSEAEGARPSEERVPRVLVIVTDG----RPQDRVAEVAAQARARGIEIYAVGVQRADVG 181
Query: 221 QLARIA--DSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICA 267
L +A HVF V F +Q + C + L AE C
Sbjct: 182 SLRTMASPPLDQHVFLVES-FDLIQEFGLQFQGRLCGKDLCAELVHGCQ 229
Score = 140 bits (349), Expect = 5e-32
Identities = 44/216 (20%), Positives = 79/216 (36%), Gaps = 20/216 (9%)
Query: 53 ATLVLICAGQGGRREDGGPACYG----GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF 107
+G R + G +C DL ++D S SV ++ + FV Q+
Sbjct: 359 GLSFHCLCPEGRRLQADGKSCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFL 418
Query: 108 I-SPQ-LRMSFIVFSTRGTTLMKL-TEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQ 164
SP+ R+ + FS+R T L + + + G T E
Sbjct: 419 DVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERG-TMTGLALRHMVEH 477
Query: 165 IYYENRQGY----RTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNET 220
+ E + V + TDG +D+ + A R+++ G ++Y VGV E
Sbjct: 478 SFSEAQGARPRDLNVPRVGLVFTDGRSQDDISVW----AARAKEEGIVMYAVGVGKAVEE 533
Query: 221 QL--ARIADSKDHVFPVNDGFQALQGIIHSILKKSC 254
+L S+ HV + F + ++ ++ C
Sbjct: 534 ELREIASEPSELHV-SYSPDFSTMTHLLENLKGSIC 568
>emb|CAC18104.1| (AL021578) dJ453C12.1.1 (matrilin 4) [Homo sapiens]
Length = 580
Score = 213 bits (537), Expect = 5e-54
Identities = 50/223 (22%), Positives = 82/223 (36%), Gaps = 17/223 (7%)
Query: 55 LVLICAGQGGRREDGGPACYGG-FDLYFILDKSGSVLH-HWNEIYYFVEQLAHKFI-SPQ 111
L+L+ + + GP C+ G DL F++D S SV + + F+ L P
Sbjct: 10 LLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPN 69
Query: 112 -LRMSFIVFSTRGTTLMKLTED-REQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYEN 169
R+ I +S++ ++ L R + + L G T + A +
Sbjct: 70 ATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQG-TMTGLAIQYAMNVAFSVA 128
Query: 170 RQGY----RTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARI 225
R V + +TDG A ++R G +Y VGV+ + L +
Sbjct: 129 EGARPPEERVPRVAVIVTDG----RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAM 184
Query: 226 A--DSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTIC 266
A +HVF V F +Q + C L AE + C
Sbjct: 185 ASPPLDEHVFLVES-FDLIQEFGLQFQSRLCAIDLCAEGTHGC 226
Score = 139 bits (347), Expect = 9e-32
Identities = 43/216 (19%), Positives = 79/216 (35%), Gaps = 20/216 (9%)
Query: 53 ATLVLICAGQGGRREDGGPACYG----GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF 107
+G + + G +C DL ++D S SV ++ + FV Q+
Sbjct: 316 GLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFL 375
Query: 108 I-SPQ-LRMSFIVFSTRGTTLMKL-TEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQ 164
SP+ R+ + FS+R T L + + + G T E
Sbjct: 376 DVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERG-TMTGLALRHMVEH 434
Query: 165 IYYENRQGY----RTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNET 220
+ E + V + TDG +D+ + A R+++ G ++Y VGV E
Sbjct: 435 SFSEAQGARPRALNVPRVGLVFTDGRSQDDISVW----AARAKEEGIVMYAVGVGKAVEA 490
Query: 221 QL--ARIADSKDHVFPVNDGFQALQGIIHSILKKSC 254
+L ++ HV D F + ++ ++ C
Sbjct: 491 ELREIASEPAELHVSYAPD-FGTMTHLLENLRGSIC 525
>ref|XP_009528.1| matrilin 4 [Homo sapiens]
Length = 581
Score = 213 bits (537), Expect = 5e-54
Identities = 50/223 (22%), Positives = 82/223 (36%), Gaps = 17/223 (7%)
Query: 55 LVLICAGQGGRREDGGPACYGG-FDLYFILDKSGSVLH-HWNEIYYFVEQLAHKFI-SPQ 111
L+L+ + + GP C+ G DL F++D S SV + + F+ L P
Sbjct: 10 LLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPN 69
Query: 112 -LRMSFIVFSTRGTTLMKLTED-REQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYEN 169
R+ I +S++ ++ L R + + L G T + A +
Sbjct: 70 ATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQG-TMTGLAIQYAMNVAFSVA 128
Query: 170 RQGY----RTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARI 225
R V + +TDG A ++R G +Y VGV+ + L +
Sbjct: 129 EGARPPEERVPRVAVIVTDG----RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAM 184
Query: 226 A--DSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTIC 266
A +HVF V F +Q + C L AE + C
Sbjct: 185 ASPPLDEHVFLVES-FDLIQEFGLQFQSRLCAIDLCAEGTHGC 226
Score = 139 bits (347), Expect = 9e-32
Identities = 43/216 (19%), Positives = 79/216 (35%), Gaps = 20/216 (9%)
Query: 53 ATLVLICAGQGGRREDGGPACYG----GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF 107
+G + + G +C DL ++D S SV ++ + FV Q+
Sbjct: 316 GLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFL 375
Query: 108 I-SPQ-LRMSFIVFSTRGTTLMKL-TEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQ 164
SP+ R+ + FS+R T L + + + G T E
Sbjct: 376 DVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERG-TMTGLALRHMVEH 434
Query: 165 IYYENRQGY----RTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNET 220
+ E + V + TDG +D+ + A R+++ G ++Y VGV E
Sbjct: 435 SFSEAQGARPRALNVPRVGLVFTDGRSQDDISVW----AARAKEEGIVMYAVGVGKAVEA 490
Query: 221 QL--ARIADSKDHVFPVNDGFQALQGIIHSILKKSC 254
+L ++ HV D F + ++ ++ C
Sbjct: 491 ELREIASEPAELHVSYAPD-FGTMTHLLENLRGSIC 525
>emb|CAC18105.1| (AL021578) dJ453C12.1.2 (matrilin 4) [Homo sapiens]
Length = 619
Score = 212 bits (534), Expect = 1e-53
Identities = 49/224 (21%), Positives = 81/224 (35%), Gaps = 17/224 (7%)
Query: 55 LVLICAGQGGRREDGGPACYGG-FDLYFILDKSGSVLH-HWNEIYYFVEQLAHKFI-SPQ 111
L+L+ + + GP C+ G DL F++D S SV + + F+ L P
Sbjct: 10 LLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPN 69
Query: 112 -LRMSFIVFSTRGTTLMKLTED-REQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYEN 169
R+ I +S++ ++ L R + + L G T + A +
Sbjct: 70 ATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQG-TMTGLAIQYAMNVAFSVA 128
Query: 170 RQGY----RTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARI 225
R V + +TDG A ++R G +Y VGV+ + L +
Sbjct: 129 EGARPPEERVPRVAVIVTDG----RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAM 184
Query: 226 A--DSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICA 267
A +HVF V F +Q + C + AE C
Sbjct: 185 ASPPLDEHVFLVES-FDLIQEFGLQFQSRLCGKDQCAEGGHGCQ 227
Score = 139 bits (347), Expect = 9e-32
Identities = 43/216 (19%), Positives = 79/216 (35%), Gaps = 20/216 (9%)
Query: 53 ATLVLICAGQGGRREDGGPACYG----GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF 107
+G + + G +C DL ++D S SV ++ + FV Q+
Sbjct: 355 GLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFL 414
Query: 108 I-SPQ-LRMSFIVFSTRGTTLMKL-TEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQ 164
SP+ R+ + FS+R T L + + + G T E
Sbjct: 415 DVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERG-TMTGLALRHMVEH 473
Query: 165 IYYENRQGY----RTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNET 220
+ E + V + TDG +D+ + A R+++ G ++Y VGV E
Sbjct: 474 SFSEAQGARPRALNVPRVGLVFTDGRSQDDISVW----AARAKEEGIVMYAVGVGKAVEA 529
Query: 221 QL--ARIADSKDHVFPVNDGFQALQGIIHSILKKSC 254
+L ++ HV D F + ++ ++ C
Sbjct: 530 ELREIASEPAELHVSYAPD-FGTMTHLLENLRGSIC 564
>ref|NP_003824.1| matrilin 4 [Homo sapiens]
emb|CAA07569.1| (AJ007581) matrilin-4 [Homo sapiens]
Length = 581
Score = 212 bits (534), Expect = 1e-53
Identities = 50/223 (22%), Positives = 82/223 (36%), Gaps = 17/223 (7%)
Query: 55 LVLICAGQGGRREDGGPACYGG-FDLYFILDKSGSVLH-HWNEIYYFVEQLAHKFI-SPQ 111
L+L+ + + GP C+ G DL F++D S SV + + F+ L P
Sbjct: 10 LLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPN 69
Query: 112 -LRMSFIVFSTRGTTLMKLTED-REQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYEN 169
R+ I +S++ ++ L R + + L G T + A +
Sbjct: 70 ATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQG-TMTGLAIQYAMNVAFSVA 128
Query: 170 RQGY----RTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARI 225
R V + +TDG A ++R G +Y VGV+ + L +
Sbjct: 129 EGARPPEERVPRVAVIVTDG----RPQDRVAEVAAQARASGIEIYAVGVQRADVGSLRAM 184
Query: 226 A--DSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTIC 266
A +HVF V F +Q + C L AE + C
Sbjct: 185 ASPPLDEHVFLVES-FDLIQEFGLQFQSRLCAIDLCAEGTHGC 226
Score = 139 bits (347), Expect = 9e-32
Identities = 43/216 (19%), Positives = 79/216 (35%), Gaps = 20/216 (9%)
Query: 53 ATLVLICAGQGGRREDGGPACYG----GFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKF 107
+G + + G +C DL ++D S SV ++ + FV Q+
Sbjct: 316 GLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFL 375
Query: 108 I-SPQ-LRMSFIVFSTRGTTLMKL-TEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQ 164
SP+ R+ + FS+R T L + + + G T E
Sbjct: 376 DVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERG-TMTGLALRHMVEH 434
Query: 165 IYYENRQGY----RTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNET 220
+ E + V + TDG +D+ + A R+++ G ++Y VGV E
Sbjct: 435 SFSEAQGARPRALNVPRVGLVFTDGRSQDDISVW----AARAKEEGIVMYAVGVGKAVEA 490
Query: 221 QL--ARIADSKDHVFPVNDGFQALQGIIHSILKKSC 254
+L ++ HV D F + ++ ++ C
Sbjct: 491 ELREIASEPAELHVSYAPD-FGTMTHLLENLRGSIC 525
>pir||A45638 immunodominant microneme protein Etp100 - Eimeria tenella
gb|AAD03350.1| (AF032905) microneme protein precursor Etmic-1 [Eimeria tenella]
Length = 712
Score = 211 bits (531), Expect = 2e-53
Identities = 57/237 (24%), Positives = 98/237 (41%), Gaps = 21/237 (8%)
Query: 40 AESPRHRLP--------VALTATLVLICAGQGGRREDGGPA--CYGGFDLYFILDKSGSV 89
A PR RL V L A + Q G G C D+ ++D+SGS+
Sbjct: 2 APLPRRRLAPCRALSLLVGLLAASFAFSSLQPGATTSSGQDQVCTSLLDVMLVVDESGSI 61
Query: 90 L-HHWNEIYYFVEQLAHKF-ISPQ-LRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKV 146
++ ++ F+E + ISP+ +R+ I F+TR L++ + +
Sbjct: 62 GTSNFRKVRQFIEDFVNSMPISPEDVRVGLITFATRSKVRWNLSDPKATNPSLAISAARS 121
Query: 147 L--PGGDTYMHEGFERASEQIYYENRQGY-RTASVIIALTDGELHEDLFFYSEREANRSR 203
L G TY H G + A + +Y N +++ +TDG +L + A R
Sbjct: 122 LSYSTGVTYTHYGLQDAKKLLYDTNAGARNNVPKLVLVMTDGAS--NLPSQTRSSAAALR 179
Query: 204 DLGAIVYCVGVK-DFNETQLARIADSKDHVFP--VNDGFQALQGIIHSILKKSCIEI 257
D GAIV +GV N ++ IA P + + + ++ I+K +C ++
Sbjct: 180 DAGAIVVVLGVGSGVNSSECRSIAGCSTSNCPRYLQSNWSNVTQQVNGIIKAACKDL 236
>gb|AAD30063.1| (AF133085) Itgae protein [Mus sp.]
Length = 895
Score = 209 bits (528), Expect = 5e-53
Identities = 43/229 (18%), Positives = 84/229 (35%), Gaps = 20/229 (8%)
Query: 65 RREDGGPACYGGFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKFISP--QLRMSFIVFST 121
R + G ++ +LD SGS+ + + F+ + F + + + +
Sbjct: 169 RTVEEEDEEEDGTEIAIVLDGSGSIEPSDFQKAKNFISTMMRNFYEKCFECNFALVQYGA 228
Query: 122 RGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTA-SVII 180
T L E R+ + V T + + I+ +R + A V++
Sbjct: 229 VIQTEFDLQESRDINASLAKVQSIVQVKEVTKTASAMQHVLDNIFIPSRGSRKKALKVMV 288
Query: 181 ALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN-------ETQLARIADSKDHVF 233
LTDG++ D + N + G + + +GV D E +L + H F
Sbjct: 289 VLTDGDIFGDPLNLT-TVINSPKMQGVVRFAIGVGDAFKNNNTYRELKLIASDPKEAHTF 347
Query: 234 PVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRH 282
V + AL G++ + + I+ E + G++ Q + GF
Sbjct: 348 KV-TNYSALDGLLSKLQQ----RIVHMEGT---VGDALQYQLAQTGFSA 388
>gb|AAC23662.1| (AF020045) integrin alpha E1 [Rattus norvegicus]
Length = 1167
Score = 209 bits (528), Expect = 5e-53
Identities = 43/229 (18%), Positives = 84/229 (35%), Gaps = 20/229 (8%)
Query: 65 RREDGGPACYGGFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKFISP--QLRMSFIVFST 121
R + G ++ +LD SGS+ + + F+ + F + + + +
Sbjct: 182 RTVEEEDEEEDGTEIAIVLDGSGSIEPSDFQKAKNFISTMMRNFYEKCFECNFALVQYGA 241
Query: 122 RGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTA-SVII 180
T L E R+ + V T + + I+ +R + A V++
Sbjct: 242 VIQTEFDLQESRDINASLAKVQSIVQVKEVTKTASAMQHVLDNIFIPSRGSRKKALKVMV 301
Query: 181 ALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN-------ETQLARIADSKDHVF 233
LTDG++ D + N + G + + +GV D E +L + H F
Sbjct: 302 VLTDGDIFGDPLNLT-TVINSPKMQGVVRFAIGVGDAFKNNNTYRELKLIASDPKEAHTF 360
Query: 234 PVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRH 282
V + AL G++ + + I+ E + G++ Q + GF
Sbjct: 361 KV-TNYSALDGLLSKLQQ----RIVHMEGT---VGDALQYQLAQTGFSA 401
>ref|NP_032425.1| integrin, alpha E, epithelial-associated [Mus musculus]
sp|Q60677|ITAE_MOUSE INTEGRIN ALPHA-E PRECURSOR (INTEGRIN ALPHA M290)
gb|AAC52142.1| (U12236) alpha M290 integrin [Mus musculus]
Length = 1167
Score = 208 bits (525), Expect = 1e-52
Identities = 43/229 (18%), Positives = 84/229 (35%), Gaps = 20/229 (8%)
Query: 65 RREDGGPACYGGFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKFISP--QLRMSFIVFST 121
R + G ++ +LD SGS+ + + F+ + F + + + +
Sbjct: 182 RTVEEEDEEEDGTEIAIVLDGSGSIGPSDFQKAKNFISTMMRNFYEKCFECNFALVQYGA 241
Query: 122 RGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTA-SVII 180
T L E R+ + V T + + I+ +R + A V++
Sbjct: 242 VIQTEFDLQESRDINASLAKVQSIVQVKEVTKTASAMQHVLDNIFIPSRGSRKKALKVMV 301
Query: 181 ALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN-------ETQLARIADSKDHVF 233
LTDG++ D + N + G + + +GV D E +L + H F
Sbjct: 302 VLTDGDIFGDPLNLT-TVINSPKMQGVVRFAIGVGDRFKNNNTYRELKLIASDPKEAHTF 360
Query: 234 PVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRH 282
V + AL G++ + + I+ E + G++ Q + GF
Sbjct: 361 KV-TNYSALDGLLSKLQQ----RIVHMEGT---VGDALQYQLAQTGFSA 401
>gb|AAC23663.1| (AF020046) integrin alpha E2 [Rattus norvegicus]
Length = 1167
Score = 206 bits (518), Expect = 8e-52
Identities = 40/229 (17%), Positives = 84/229 (36%), Gaps = 20/229 (8%)
Query: 65 RREDGGPACYGGFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKFISP--QLRMSFIVFST 121
+ + G ++ +LD SGS+ + + F+ + F + + + +
Sbjct: 182 QAVEEEDEEEAGTEIAIVLDGSGSIEPSDFQKAKDFISTMMRNFYEKCFECNFALVQYGG 241
Query: 122 RGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTA-SVII 180
T L + R+ + V T + + I+ +R + A V++
Sbjct: 242 VIQTEFDLLDSRDINASLAKVQSIVQVKEVTKTASAMQHVLDNIFIPSRGSRKKALKVMV 301
Query: 181 ALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFN-------ETQLARIADSKDHVF 233
LTDG++ D + + S+ G + + +GV + E +L H F
Sbjct: 302 VLTDGDIFRDPLNLT-TVISSSKMQGVVRFAIGVGNAFENNNTYRELKLIASDPKAAHTF 360
Query: 234 PVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRH 282
V + AL G++ + + I+ E + G++ Q + GF
Sbjct: 361 KV-TNYSALDGLLSKLQQ----RIIHMEGT---VGDTLQYQLAQTGFSA 401
>gb|AAF01565.1|AF061273_1 (AF061273) thrombospondin-related adhesive protein homolog
[Neospora caninum]
Length = 765
Score = 204 bits (513), Expect = 3e-51
Identities = 45/206 (21%), Positives = 84/206 (39%), Gaps = 13/206 (6%)
Query: 63 GGRREDGGPACYGGFDLYFILDKSGSVLH-HWNEIYYFVEQLAHKFI--SPQLRMSFIVF 119
G C D+ F++D SGS+ H+ E+ F+ K + ++ S ++F
Sbjct: 62 SGGTIGAAEGCTSQLDICFLVDSSGSIGEAHYEEVKQFLHAFLSKLPIGNDEVNTSLVIF 121
Query: 120 STRGTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIY-YENRQGYRTA 176
ST L + ++ + +P GG T G + ++ ++ Y +
Sbjct: 122 STTVHPHWSLRANNASDKETAMQDVLTIPYHGGTTNTAAGLQTCNQMLFDYPREERQTVP 181
Query: 177 SVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVK-DFNETQLARIADSKDHVFP- 234
++IA+TDGE D F++ EA R+ G I+ + V N + + ++ P
Sbjct: 182 KLVIAMTDGESDSD--FHTVNEAKVIRERGGIITVLSVGMYVNHNECRSMCGCRNDSSPC 239
Query: 235 ---VNDGFQALQGIIHSILKKSCIEI 257
+ + L I ILK+ C +
Sbjct: 240 PLYLQTEWSQLLPSISPILKEVCKTL 265
>pir||A48569 antigen Em100 - Eimeria maxima
gb|AAA29076.1| (M99058) em100 gene is homologous the Eimeria tenella gene et100
(accession number M73495) encoding the microneme protein
Etp100 [Eimeria maxima]
Length = 724
Score = 201 bits (506), Expect = 2e-50
Identities = 56/237 (23%), Positives = 95/237 (39%), Gaps = 21/237 (8%)
Query: 40 AESPRHRL-PVALTATLVLICAG------QGGRREDGGPACYGGFDLYFILDKSGSVL-H 91
A P RL P + LV + AG + C D+ ++D+SGS+
Sbjct: 2 ALLPTQRLAPGWALSLLVFLAAGLTFHSSHAAASSEADQVCTRLLDVMLVVDESGSIGTS 61
Query: 92 HWNEIYYFVEQLAHKF-ISP-QLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLP- 148
++ ++ F+ A +SP +R+ + F T T L++ R Q L K LP
Sbjct: 62 NYGKVRSFISNFAGTMPLSPDDVRVGLVTFGTSAVTRWDLSDSRAQNADLLAAAAKKLPY 121
Query: 149 -GGDTYMHEGFERASEQIYYENRQGYRT-ASVIIALTDGELHEDLFFYSEREANRSRDLG 206
G TY H G +A E ++ + G +I+ +TDG S A + R+ G
Sbjct: 122 AAGSTYTHLGLAKAEEILFSFQKGGRDNAPKMILVMTDGASSRRSQTLS--AAEKLRNRG 179
Query: 207 AIVYCVGVK-DFNETQLARIADSKDH-----VFPVNDGFQALQGIIHSILKKSCIEI 257
I+ +GV N + IA + + + I+ I+K +C ++
Sbjct: 180 VIIVVLGVGTGVNSAECRSIAGCDTSDTVECPRYLQSNWGGVSSQINGIIKAACKDL 236
>gb|AAB63303.1| (U62660) micronemal protein MIC2 [Toxoplasma gondii]
Length = 769
Score = 199 bits (500), Expect = 1e-49
Identities = 43/210 (20%), Positives = 78/210 (36%), Gaps = 16/210 (7%)
Query: 62 QGGRREDGGPACYGGFDLYFILDKSGSVL-HHWNEIYYFVEQLAHKF-ISP-QLRMSFIV 118
Q C D+ F++D SGS+ ++ + F+ I P ++ + +
Sbjct: 60 QSDSAIGAAEGCTNQLDICFLIDSSGSIGIQNFRLVKQFLHTFLMVLPIGPEEVNNAVVT 119
Query: 119 FSTRGTTLMKLTEDREQIRQGLEELQKVLP--GGDTYMHEGFERASEQIYYENRQGYR-T 175
+ST L +Q +P G T +G + + ++ +R G
Sbjct: 120 YSTDVHLQWDLQSPNAVDKQLAAHAVLEMPYKKGSTNTSDGLKACKQILFTGSRPGREHV 179
Query: 176 ASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKD-FNETQLARIADS-----K 229
++I +TDGE D F + R A R+LG IV + V ++ +
Sbjct: 180 PKLVIGMTDGESDSD--FRTVRAAKEIRELGGIVTVLAVGHYVKHSECRSMCGCSGTSDD 237
Query: 230 DHVFP--VNDGFQALQGIIHSILKKSCIEI 257
D P + + L I +LK+ C +
Sbjct: 238 DSPCPLYLRADWGQLATAIKPMLKEVCKTL 267
CPU time: 70.39 user secs. 2.36 sys. secs 72.75 total secs.
Database: nr
Posted date: Dec 10, 2000 7:21 PM
Number of letters in database: 188,047,558
Number of sequences in database: 594,795
Lambda K H
0.319 0.138 0.421
Gapped
Lambda K H
0.270 0.0518 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 210402107
Number of Sequences: 594795
Number of extensions: 9641651
Number of successful extensions: 20251
Number of sequences better than 10.0: 436
Number of HSP's better than 10.0 without gapping: 196
Number of HSP's successfully gapped in prelim test: 240
Number of HSP's that attempted gapping in prelim test: 18366
Number of HSP's gapped (non-prelim): 735
length of query: 598
length of database: 188,047,558
effective HSP length: 55
effective length of query: 543
effective length of database: 155,333,833
effective search space: 84346271319
effective search space used: 84346271319
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 74 (33.1 bits)