Legend:
Sequences with E-value BETTER than threshold 758 0.0
215 7e-55
212 7e-54
179 5e-44
178 1e-43
173 5e-42
172 9e-42
156 4e-37
156 4e-37
154 2e-36
152 8e-36
148 1e-34
146 4e-34
139 4e-32
133 5e-30
121 1e-26
119 8e-26
118 1e-25
118 1e-25
118 1e-25
118 1e-25
118 1e-25
116 4e-25
116 5e-25
114 2e-24
111 1e-23
109 6e-23
109 8e-23
104 3e-21
104 3e-21
99 7e-20
99 1e-19
88 2e-16
79 9e-14
77 3e-13
76 7e-13
75 2e-12
74 3e-12
74 3e-12
74 3e-12
71 2e-11
69 9e-11
67 3e-10
67 3e-10
67 5e-10
65 2e-09
63 6e-09
62 2e-08
59 1e-07
Alignments
>ref|NP_065138.1| tumor endothelial marker 7 precursor [Homo sapiens]
gb|AAG00869.1|AF279144_1 (AF279144) tumor endothelial marker 7 precursor [Homo sapiens]
Length = 502
Score = 758 bits (1938), Expect = 0.0
Identities = 420/420 (100%), Positives = 420/420 (100%)
Query: 1 MRGELWLLVLVLREAARALSPQPGAGHDEGPGSGWAAKGTVRGWNRRARESPGHVSEPDR 60
MRGELWLLVLVLREAARALSPQPGAGHDEGPGSGWAAKGTVRGWNRRARESPGHVSEPDR
Sbjct: 1 MRGELWLLVLVLREAARALSPQPGAGHDEGPGSGWAAKGTVRGWNRRARESPGHVSEPDR 60
Query: 61 TQLSQDLGGGTLAMDTLPDNRTRVVEDNHSYYVSRLYGPSEPHSRELWVDVAEANRSQVK 120
TQLSQDLGGGTLAMDTLPDNRTRVVEDNHSYYVSRLYGPSEPHSRELWVDVAEANRSQVK
Sbjct: 61 TQLSQDLGGGTLAMDTLPDNRTRVVEDNHSYYVSRLYGPSEPHSRELWVDVAEANRSQVK 120
Query: 121 IHTILSNTHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVIHRMLTATQYVAPLMA 180
IHTILSNTHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVIHRMLTATQYVAPLMA
Sbjct: 121 IHTILSNTHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVIHRMLTATQYVAPLMA 180
Query: 181 NFNPGYSDNSTVVYFDNGTVFVVQWDHVYLQGWEDKGSFTFQAALHHDGRIVFAYKEIPM 240
NFNPGYSDNSTVVYFDNGTVFVVQWDHVYLQGWEDKGSFTFQAALHHDGRIVFAYKEIPM
Sbjct: 181 NFNPGYSDNSTVVYFDNGTVFVVQWDHVYLQGWEDKGSFTFQAALHHDGRIVFAYKEIPM 240
Query: 241 SVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPSKVTSMSAVEFTP 300
SVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPSKVTSMSAVEFTP
Sbjct: 241 SVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPSKVTSMSAVEFTP 300
Query: 301 LPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTMGCAQEAEGQDVRGL 360
LPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTMGCAQEAEGQDVRGL
Sbjct: 301 LPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTMGCAQEAEGQDVRGL 360
Query: 361 PGMRTTTSASPDTSFSPYDGDLTTTSSSLFIDSLTTEDDTKLNPYAGGDGLQNNLSPKTK 420
PGMRTTTSASPDTSFSPYDGDLTTTSSSLFIDSLTTEDDTKLNPYAGGDGLQNNLSPKTK
Sbjct: 361 PGMRTTTSASPDTSFSPYDGDLTTTSSSLFIDSLTTEDDTKLNPYAGGDGLQNNLSPKTK 420
>ref|NP_059984.1| SEX gene [Homo sapiens]
sp|P51805|PLX4_HUMAN PLEXIN 4 PRECURSOR (TRANSMEMBRANE PROTEIN SEX)
emb|CAA61132.1| (X87852) SEX protein [Homo sapiens]
Length = 1871
Score = 215 bits (543), Expect = 7e-55
Identities = 39/148 (26%), Positives = 53/148 (35%), Gaps = 7/148 (4%)
Query: 227 HDG-RIVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIEL 285
DG V AY SV I + +K D F + VP I
Sbjct: 411 TDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLFSP 470
Query: 286 D--PSKVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWD 343
D + S V P+ TC Q++SC AC+ S +C WC + RC
Sbjct: 471 DHRHIYLLSEKQVSQLPVETCEQYQSCAACLGS-GDPHCGWCVLRHRCCREGACLGA--S 527
Query: 344 GTMGCAQE-AEGQDVRGLPGMRTTTSAS 370
G A+E ++ VR P + TS
Sbjct: 528 APHGFAEELSKCVQVRVRPNNVSVTSPG 555
Score = 51.5 bits (122), Expect = 2e-05
Identities = 15/80 (18%), Positives = 21/80 (25%), Gaps = 9/80 (11%)
Query: 305 LQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTMGCAQEAEGQDVRGLP--- 361
Q SC C+ +D FNC WC RC + + + R
Sbjct: 788 AQRPSCGLCLKADPRFNCGWCISEHRCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHP 847
Query: 362 ------GMRTTTSASPDTSF 375
G T +
Sbjct: 848 LVGPKEGGTRVTIVGENLGL 867
Score = 41.0 bits (95), Expect = 0.025
Identities = 13/56 (23%), Positives = 18/56 (31%), Gaps = 6/56 (10%)
Query: 303 TCLQHRSCDACMSSDLTFN-CSWCHVLQRCSSG-FDRYRQEWDGTMGCAQEAEGQD 356
C +SC +C+ S C WC C+S + QE E
Sbjct: 637 NCSVLQSCMSCVGS---PYPCHWCKYRHTCTSRPHECSFQE-GRVHSPEGCPEILP 688
>ref|NP_032909.1| plexin 3 [Mus musculus]
pir||JC4976 plexin 3 precursor - mouse
dbj|BAA13190.1| (D86950) plexin 3 [Mus musculus]
Length = 1872
Score = 212 bits (535), Expect = 7e-54
Identities = 37/148 (25%), Positives = 51/148 (34%), Gaps = 7/148 (4%)
Query: 227 HDG-RIVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIEL 285
DG V AY SV I + +K D V + I
Sbjct: 412 TDGMASVAAYTYHQHSVVFIGTRSGNLKKVRVDGSQDAQLYETVSVVQGSPILRDLLFSP 471
Query: 286 D--PSKVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWD 343
D + S V P+ TC Q+ SC AC+ S +C WC + RC
Sbjct: 472 DHRHIYLLSEKQVSQLPVETCEQYLSCAACLGS-GDPHCGWCVLQHRCCREGACPGA--S 528
Query: 344 GTMGCAQE-AEGQDVRGLPGMRTTTSAS 370
G A+E ++ VR P + TS+
Sbjct: 529 APHGFAEELSKCIQVRVRPNNVSVTSSG 556
Score = 55.0 bits (131), Expect = 2e-06
Identities = 24/147 (16%), Positives = 37/147 (24%), Gaps = 12/147 (8%)
Query: 242 VPEISSSQHPVKTGLSDAFMILNPSPDVPESRRR--SIFEYHRIELDPSKVTSMSAVEFT 299
V + QH V ++ + + + D
Sbjct: 723 VVRVQGRQHRVPAVRFNSSSVQCQNASYFYEGDEFGDTELDFSVVWDGDFPIDKPPSFRA 782
Query: 300 PLPTC-LQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDR--YRQEWDGTMGC-AQE--AE 353
L C Q SC C+ +D FNC WC RC + W A+
Sbjct: 783 LLYKCWAQRPSCGLCLKADPRFNCGWCISEHRCQLRAHCPAPKSNWMHPSQKGARCSHPR 842
Query: 354 GQDVRGL----PGMRTTTSASPDTSFS 376
+ L G T + +
Sbjct: 843 ITQIHPLTGPKEGGTRVTIVGENLGLT 869
Score = 39.1 bits (90), Expect = 0.096
Identities = 12/56 (21%), Positives = 17/56 (29%), Gaps = 6/56 (10%)
Query: 303 TCLQHRSCDACMSSDLTFN-CSWCHVLQRCS-SGFDRYRQEWDGTMGCAQEAEGQD 356
C +SC +C+ S C WC C+ + QE E
Sbjct: 638 NCSALQSCMSCVGS---PYPCHWCKYRHVCTSHPHECSFQE-GRVHSPEGCPEILP 689
>ref|NP_005752.1| plexin C1; receptor for virally-encoded semaphorin; plexin
(semaphorin receptor) [Homo sapiens]
pir||T09074 semaphorin receptor VESPR - human
gb|AAC18823.1| (AF030339) VESPR [Homo sapiens]
Length = 1568
Score = 179 bits (451), Expect = 5e-44
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 15/170 (8%)
Query: 218 SFTFQAALHHDGRIVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSI 277
+H D V+ + +V + + + + + N P+V +
Sbjct: 365 PIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSN-CPEVIYEIKEET 423
Query: 278 FEYHRIELDP-----SKVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCS 332
++++ DP +T+ V + C +H+SC C+++ +C WCH LQRC+
Sbjct: 424 PVFYKLVPDPVKNIYIYLTAGKEVRRIRVANCNKHKSCSECLTAT-DPHCGWCHSLQRCT 482
Query: 333 SGFDRYRQE----W-DGTMGCAQEAEGQDVRGLPGMRTTTSASPDTSFSP 377
D E W D + G + + Q +R T T SFSP
Sbjct: 483 FQGDCVHSENLENWLDISSGAKKCPKIQIIRSSKEKTTVTMVG---SFSP 529
Score = 36.3 bits (83), Expect = 0.67
Identities = 11/51 (21%), Positives = 19/51 (36%), Gaps = 7/51 (13%)
Query: 303 TCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGF-DRYRQEWDGTMGCAQEA 352
C + C AC+ + C+WC +RC F +++ Q
Sbjct: 591 NCSSLKECPACVETG----CAWCKSARRCIHPFTACDPSDYERNQ--EQCP 635
>gb|AAF46578.1| (AE003450) CG2221 gene product [Drosophila melanogaster]
Length = 625
Score = 178 bits (448), Expect = 1e-43
Identities = 114/264 (43%), Positives = 162/264 (61%), Gaps = 10/264 (3%)
Query: 87 DNHSYYVSRLYGPSEPHSRELWVDVAEANRSQVKIHTILSNTHRQASRVVLSFDFPFYGH 146
D H YY S LY ++ LW ++ + +LS++HR+A V L FDFPFYGH
Sbjct: 214 DFHEYYNSVLY-ENKDEVASLWTELKATPE-----NIMLSSSHRRAMTVELKFDFPFYGH 267
Query: 147 PLRQITIATGGFIFMGDVIHRMLTATQYVAPLMANFNPGYSDNSTVVYFDNGTVFVVQWD 206
+R IT+ATGGF++ G+ +H L ATQY+APLMANF+ S++S V DNGT F W+
Sbjct: 268 FVRNITVATGGFLYTGEYVHSWLAATQYIAPLMANFDTSMSNDSFVRLHDNGTAFTAVWE 327
Query: 207 HVYLQGWEDKGSFTFQAALHHDGRIVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPS 266
+V LQ D G FTF L+ G IVFAY +P ++ I +HPVK GLSDA++I
Sbjct: 328 NVTLQDKPDFGKFTFSVTLYQSGDIVFAYMLVPTNINSIQDKEHPVKVGLSDAYII---D 384
Query: 267 PDVPESRRRSIFEYHRIELDPSKVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCH 326
+ +RR++I+EYHR+ ++T+ + ++ PTCL + C++C++ + TF C WC
Sbjct: 385 KQLFFARRKTIYEYHRVTFQQHEITNNTIIKLAAQPTCLGYNDCNSCINHNTTFTCLWCS 444
Query: 327 VLQRCSSGFDRYRQEWDGTMGCAQ 350
VL RCS+G DR + EW MGC
Sbjct: 445 VLNRCSTGTDRKKHEWLQ-MGCEA 467
>pir||T19786 hypothetical protein C36E8.3 - Caenorhabditis elegans
emb|CAA84646.1| (Z35597) Weak similarity with sea squirt nidogen precursor protein
(blastp score 71)~cDNA EST EMBL:T02069 comes from this
gene~cDNA EST yk114g11.5 comes from this gene~cDNA EST
yk114g11.3 comes from this gene~cDNA EST yk85g6.3 comes
from this gene~cDNA>
Length = 476
Score = 173 bits (434), Expect = 5e-42
Identities = 104/255 (40%), Positives = 152/255 (58%), Gaps = 9/255 (3%)
Query: 78 PDNRTRVVEDNHSYYVSRLYGPSEPHSRELWVDVAEANRSQVKI----HTILSNTHRQAS 133
PD + +H YY + + ++ W++V + + + H +LS ++R+A
Sbjct: 93 PDVEVKNDMIDHQYYQAETFVGDGETLKKYWINVEQFMKKPKAVGNTSHPLLSQSYRRAV 152
Query: 134 RVVLSFDFPFYGHPLRQITIATGGFIFMGDVIHRMLTATQYVAPLMANFNPGYSDNSTVV 193
L F FPFYGH + +TIATGGFI++GD H L ATQY+APLMANF+ Y +NS +V
Sbjct: 153 GARLQFKFPFYGHKMSNLTIATGGFIYIGDHSHNWLAATQYIAPLMANFHT-YLNNSNIV 211
Query: 194 YFDNGTVFVVQWDHVYLQGWEDKGSFTFQAALHHDGRIVFAYKEIPMSVPEISSSQHPVK 253
Y D+G +FVV+W +V L+ +D+ SFTFQ LH +G IVF YK++P + IS + HPVK
Sbjct: 212 YADDGELFVVEWRNVQLKEDKDEHSFTFQTILHKNGDIVFIYKDVPYDISNISDANHPVK 271
Query: 254 TGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPSKVTSMSAVEFTPLPTCLQHRSCDAC 313
G+SDA+M + +R I+EYHRIE+ K+ S + V PTC+ +CD C
Sbjct: 272 LGISDAYMFKHNLHQAAVP-KRVIYEYHRIEIAAQKIVSNTVVILKAQPTCISFDTCDTC 330
Query: 314 MSSDLTFN--CSWCH 326
++ L + C WCH
Sbjct: 331 TNATL-PHFNCLWCH 344
>ref|NP_061267.1| plexin C1; viral-encoded semaphorin protein receptor [Mus musculus]
gb|AAF01334.1|AF190578_1 (AF190578) receptor for viral-encoded semaphorin protein [Mus
musculus]
Length = 1574
Score = 172 bits (432), Expect = 9e-42
Identities = 31/163 (19%), Positives = 60/163 (36%), Gaps = 12/163 (7%)
Query: 218 SFTFQAALHHDGRIVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSI 277
+H D V+ + +V + + + + + N P+V +
Sbjct: 365 PIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVVLGENLTSN-CPEVIYEIKEET 423
Query: 278 FEYHRIELDPS-----KVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCS 332
++++ P +T+ V P+ C + +SC C+++ +C WC LQRC+
Sbjct: 424 PVFYKLVPHPMKNIYIYLTAGKEVRRIPVANCSKRKSCSECLAA-ADPHCGWCLPLQRCT 482
Query: 333 SGFDRYRQ----EW-DGTMGCAQEAEGQDVRGLPGMRTTTSAS 370
D W D + G + + Q +R L T T
Sbjct: 483 FQGDCTHAGSFENWLDISSGPKKCPKIQILRSLRERTTVTIVG 525
>pir||T30243 alpha tectorin - chicken
emb|CAA09979.1| (AJ012287) alpha tectorin [Gallus gallus]
Length = 2120
Score = 156 bits (392), Expect = 4e-37
Identities = 34/141 (24%), Positives = 50/141 (35%), Gaps = 34/141 (24%)
Query: 132 ASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVIHR-------MLTATQYVAPLMANF-- 182
+S + LS F F+ P R + + G I ++ + + +VAP +
Sbjct: 46 SSEIKLSVPFIFFRSPYRTVYVNNNGVISFNSLVSQFTPEAFPLADGRAFVAPFCGDVAN 105
Query: 183 ------------NPGYSDNST---------VVYFDNGTVFVVQWDHVYLQGWEDKGSF-T 220
NP S+ + F VF+V W+ V G T
Sbjct: 106 GIRGEIYYRESTNPELLGESSKDIRKYFKDMASFSASWVFIVTWEEVQFYGGSSTTPVNT 165
Query: 221 FQAALHHDGRIVFA---YKEI 238
FQA L DG FA Y+EI
Sbjct: 166 FQAVLITDGVSSFAIFNYQEI 186
>pir||I51553 Plexin - African clawed frog
dbj|BAA07374.1| (D38175) plexin [Xenopus laevis]
Length = 1905
Score = 156 bits (392), Expect = 4e-37
Identities = 28/143 (19%), Positives = 51/143 (35%), Gaps = 8/143 (5%)
Query: 231 IVFAYKEIPMSVPEISSSQHPVKTGLSD----AFMILNPSPDVPESRRRSIFEYHRIELD 286
V AY +V + VK L D + ++ +V +I + D
Sbjct: 427 SVAAYDYRGHTVVFAGTRSGRVKKILVDLSASSSHLVQQYENVVVHEGNAILRDLVLSPD 486
Query: 287 PSKV--TSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDG 344
+ + V P+ +C Q+ SCD C+ S +C WC + CS R + +
Sbjct: 487 RQYIYAMTEKQVTRVPVESCEQYESCDTCLGS-RDPHCGWCVLHNMCSRKDKCERAD-EL 544
Query: 345 TMGCAQEAEGQDVRGLPGMRTTT 367
+ + + + P + T
Sbjct: 545 HRFTSDQRQCVQLTVHPKNISVT 567
Score = 56.2 bits (134), Expect = 6e-07
Identities = 15/83 (18%), Positives = 21/83 (25%), Gaps = 15/83 (18%)
Query: 309 SCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDG------------TMGCAQEAEGQD 356
SC C+ SD F C WC ++C+ + E E
Sbjct: 806 SCGLCLKSDRRFECGWCVSEKKCTLRQNCPTLENPWMHASTANSRCTDPKITKLFPETGP 865
Query: 357 VRGLPGMRTTTSASPDTSFSPYD 379
G T + D
Sbjct: 866 ---RQGGTRLTITGENLGLRFED 885
Score = 43.0 bits (100), Expect = 0.006
Identities = 17/72 (23%), Positives = 24/72 (32%), Gaps = 6/72 (8%)
Query: 303 TCLQHRSCDACMSSDLTFNCSWCHVLQRCSS-GFDRYRQEWDGTMGCAQEAEGQDVRGLP 361
C H+SC +C+ + +F C WC C+ D QE M Q +
Sbjct: 651 NCSVHQSCLSCV--NGSFPCHWCKYRHVCTHNAADCSFQEGRVNM-SEDCP--QILPSSQ 705
Query: 362 GMRTTTSASPDT 373
P T
Sbjct: 706 IYIPVGVVKPIT 717
>pir||S31213 nidogen precursor - sea squirt (Halocynthia roretzi)
dbj|BAA03127.1| (D14038) entactin/nidogen [Halocynthia roretzi]
Length = 1161
Score = 154 bits (386), Expect = 2e-36
Identities = 36/123 (29%), Positives = 50/123 (40%), Gaps = 25/123 (20%)
Query: 136 VLSFDFPFYGHPLRQITIATGGFIFMGDVIHRMLTATQYVAPLMANFNPGYS-------- 187
LS FY +T+ T GFI + +V +AP M++ + S
Sbjct: 46 KLSMPIVFYDQKYDSVTVHTDGFITLENVGADT-DGEVLLAPFMSDLDTELSGDIFFREH 104
Query: 188 -DNSTVVY---------------FDNGTVFVVQWDHVYLQGWEDKGSFTFQAALHHDGRI 231
DN+T+ F+ G+VFVV WD V ED +FTFQ + DG
Sbjct: 105 KDNATIARANTDVREAFIETAGDFNAGSVFVVTWDKVQSASREDGVTFTFQCIVATDGAA 164
Query: 232 VFA 234
FA
Sbjct: 165 TFA 167
>emb|CAB57274.1| (X87832) NOV/plexin-A1 protein [Homo sapiens]
Length = 1754
Score = 152 bits (381), Expect = 8e-36
Identities = 25/144 (17%), Positives = 46/144 (31%), Gaps = 8/144 (5%)
Query: 231 IVFAYKEIPMSVPEISSSQHPVKTGLSD----AFMILNPSPDVPESRRRSIFEYHRIELD 286
V AY +V + ++ L D V I + +
Sbjct: 414 AVAAYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSPN 473
Query: 287 PSKV--TSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDG 344
+ + V P+ +C+Q+ SC+ C+ S +C WC + CS R + +
Sbjct: 474 HQYLYAMTEKQVTRVPVESCVQYTSCELCLGS-RDPHCGWCVLHSICSRRDACERAD-EP 531
Query: 345 TMGCAQEAEGQDVRGLPGMRTTTS 368
A + + P + T
Sbjct: 532 QRFAADLLQCVQLTVQPRNVSVTM 555
Score = 55.0 bits (131), Expect = 1e-06
Identities = 17/81 (20%), Positives = 27/81 (32%), Gaps = 10/81 (12%)
Query: 309 SCDACMSSDLTFNCSWCHVLQRCSSGFDR---YRQEWD-GTMGCAQEAEGQDVRGLP--- 361
SC C+ +D F C WC +RCS W G ++ + + ++ P
Sbjct: 793 SCGLCLKADPRFECGWCVAERRCSLRHHCAADTPASWMHARHGSSRCTDPKILKLSPETG 852
Query: 362 ---GMRTTTSASPDTSFSPYD 379
G T + D
Sbjct: 853 PRQGGTRLTITGENLGLRFED 873
Score = 35.9 bits (82), Expect = 0.74
Identities = 15/72 (20%), Positives = 23/72 (31%), Gaps = 6/72 (8%)
Query: 303 TCLQHRSCDACMSSDLTFNCSWCHVLQRCSSG-FDRYRQEWDGTMGCAQEAEGQDVRGLP 361
C H+SC +C+ + +F C WC C+ D E + Q +
Sbjct: 638 NCSVHQSCLSCV--NGSFPCHWCKYRHVCTHNVADCAFLEGRVNV-SEDCP--QILPSTQ 692
Query: 362 GMRTTTSASPDT 373
P T
Sbjct: 693 IYVPVGVVKPIT 704
>pir||JC4975 plexin 2 precursor - mouse
dbj|BAA13189.1| (D86949) plexin 2 [Mus musculus]
Length = 1884
Score = 148 bits (371), Expect = 1e-34
Identities = 29/149 (19%), Positives = 49/149 (32%), Gaps = 6/149 (4%)
Query: 231 IVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNP-SPDVPE-SRRRSIFEYHRIELDP- 287
V +Y SV + + +K +D V I ++
Sbjct: 424 SVASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVFKDGSPILRDMAFSINQL 483
Query: 288 -SKVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTM 346
V S V P+ +C Q+ +C C+SS +C WC + CS R W+
Sbjct: 484 YLYVMSERQVTRVPVESCEQYTTCGECLSS-GDPHCGWCALHNMCSRRDKCQRA-WEANR 541
Query: 347 GCAQEAEGQDVRGLPGMRTTTSASPDTSF 375
A ++ + P + + S S
Sbjct: 542 FAASISQCMSLEVHPNSISVSDHSRLLSL 570
Score = 56.2 bits (134), Expect = 7e-07
Identities = 32/169 (18%), Positives = 50/169 (28%), Gaps = 34/169 (20%)
Query: 221 FQAALHHDGRIVFAYKEIPMSVPEISSSQHPVKTGLS----DAFMILNPSPDVPESRRRS 276
++ L G + VP + + V+ S D I N + D +
Sbjct: 727 YECVLSIQGAV--------HRVPALRFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGN 778
Query: 277 IFEYHRIELDPSKVTSMSAVEFTPLPTC-LQHRSCDACMSSDLTFNCSWCHVLQRCSSGF 335
+P + L C Q SC C+ +D F C WC +RC+
Sbjct: 779 FIID-----NPQDL-------KVHLYKCAAQRESCGLCLKADHKFECGWCSGERRCTLHQ 826
Query: 336 DR--YRQEW-DGTMGCAQEAEGQD-----VRGLP-GMRTTTSASPDTSF 375
W D + + + Q V G P G T +
Sbjct: 827 HCPSTSSPWLDWSSHNVKCSNPQITEILTVSGPPEGGTRVTIHGVNLGL 875
>ref|NP_032907.1| plexin 1 [Mus musculus]
pir||JC4980 plexin 1 precursor - mouse
dbj|BAA13188.1| (D86948) plexin 1 [Mus musculus]
Length = 1894
Score = 146 bits (366), Expect = 4e-34
Identities = 27/147 (18%), Positives = 49/147 (32%), Gaps = 14/147 (9%)
Query: 231 IVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNP-------SPDVPESRRRSIFEYHRI 283
V AY +V + ++ L D + NP V I +
Sbjct: 434 AVAAYDYQGRTVVFAGTRSGRIRKILVD---LANPSGRPALAYESVVAQEGNPILRDLVL 490
Query: 284 ELDPSKV--TSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQE 341
+ + + V P+ +C+Q+ SC+ C+ S +C WC + CS R E
Sbjct: 491 SPNRQYLYAMTEKQVTQVPVESCVQYTSCELCLGS-RDPHCGWCVLHSICSRQDACERAE 549
Query: 342 WDGTMGCAQEAEGQDVRGLPGMRTTTS 368
+ + + + P + T
Sbjct: 550 -EPQRFASDLLQCVQLTVQPRNVSVTM 575
Score = 55.0 bits (131), Expect = 1e-06
Identities = 17/81 (20%), Positives = 27/81 (32%), Gaps = 10/81 (12%)
Query: 309 SCDACMSSDLTFNCSWCHVLQRCSSGFDRYR---QEWD-GTMGCAQEAEGQDVRGLP--- 361
SC C+ +D F C WC +RCS W G ++ + + ++ P
Sbjct: 813 SCGLCLKADPRFECGWCVAERRCSLRHHCPADSPASWMHAHHGSSRCTDPKILKLSPETG 872
Query: 362 ---GMRTTTSASPDTSFSPYD 379
G T + D
Sbjct: 873 PRQGGTRLTITGENLGLRFED 893
Score = 35.6 bits (81), Expect = 1.1
Identities = 14/55 (25%), Positives = 21/55 (37%), Gaps = 4/55 (7%)
Query: 303 TCLQHRSCDACMSSDLTFNCSWCHVLQRCS-SGFDRYRQEWDGTMGCAQEAEGQD 356
C H+SC AC+ + +F C WC C+ + D E M +
Sbjct: 658 NCSVHQSCLACV--NGSFPCHWCKYRHVCTNNAADCAFLEGRVNM-SEDCPQILP 709
>dbj|BAA21571.1| (AB002313) KIAA0315 [Homo sapiens]
Length = 1841
Score = 139 bits (349), Expect = 4e-32
Identities = 42/221 (19%), Positives = 66/221 (29%), Gaps = 25/221 (11%)
Query: 174 YVAPLMANFNPGYSDNSTVVYFDNGTVFVVQWDHV-YLQGWEDKGSFTFQAALHHDGRIV 232
+ P + G + F G+ +H+ Y G D T A L G +
Sbjct: 344 FYKPFHGDIQCGGHAPGSSKSFPCGS------EHLPYPLGSRDGLRGT--AVLQRGGLNL 395
Query: 233 FAYK---EIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELD--P 287
A E +V + +S + + + + + + D
Sbjct: 396 TAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLVLSGDLGS 455
Query: 288 SKVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQE------ 341
+ V P+ CL + +C C S C WC V RC+ + R E
Sbjct: 456 LYAMTQDKVFRLPVQECLSYPTCTQCRDSQ-DPYCGWCVVEGRCTRKAECPRAEEASHWL 514
Query: 342 WDGTMGCAQEAEGQ---DVRGLPGMRTTTSASPDTSFSPYD 379
W + C Q R G T SP + S D
Sbjct: 515 WSRSKSCVAVTSAQPQNMSRRAQGEVQLT-VSPLPALSEED 554
Score = 44.9 bits (105), Expect = 0.002
Identities = 13/83 (15%), Positives = 22/83 (25%), Gaps = 13/83 (15%)
Query: 285 LDPSKVTS-MSAVEF---TPLPTCL-QHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYR 339
V S ++ L C C C +++ + C+WC RC
Sbjct: 740 PLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCAWCGGQSRCVYEALCNT 799
Query: 340 QEWDGTMGCAQEAEGQDVRGLPG 362
++ R P
Sbjct: 800 --------TSECPPPVITRIQPE 814
>emb|CAB57275.1| (X87831) OCT/plexin-A2 protein [Homo sapiens]
Length = 1328
Score = 133 bits (332), Expect = 5e-30
Identities = 26/136 (19%), Positives = 45/136 (32%), Gaps = 6/136 (4%)
Query: 244 EISSSQHPVKTGLSDAFMILNP-SPDVPE-SRRRSIFEYHRIELDP--SKVTSMSAVEFT 299
+ + +K +D V I +D V S V
Sbjct: 1 FVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFSIDQRYLYVMSERQVTRV 60
Query: 300 PLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTMGCAQEAEGQDVRG 359
P+ +C Q+ +C C+SS +C WC + CS +Q W+ A ++ +
Sbjct: 61 PVESCEQYTTCGECLSS-GDPHCGWCALHNMCSRRDKC-QQAWEPNRFAASISQCVSLAV 118
Query: 360 LPGMRTTTSASPDTSF 375
P + + S S
Sbjct: 119 HPSSISVSEHSRLLSL 134
Score = 58.2 bits (139), Expect = 2e-07
Identities = 33/169 (19%), Positives = 51/169 (29%), Gaps = 34/169 (20%)
Query: 221 FQAALHHDGRIVFAYKEIPMSVPEISSSQHPVKTGLS----DAFMILNPSPDVPESRRRS 276
++ L+ G I VP + + V+ S D I N + D +
Sbjct: 291 YECVLNIQGAI--------HRVPALRFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGN 342
Query: 277 IFEYHRIELDPSKVTSMSAVEFTPLPTC-LQHRSCDACMSSDLTFNCSWCHVLQRCSSGF 335
+P + L C Q SC C+ +D F C WC +RC+
Sbjct: 343 FIID-----NPQDL-------KVHLYKCAAQRESCGLCLKADRKFECGWCSGERRCTLHQ 390
Query: 336 DRY--RQEW-DGTMGCAQEAEGQD-----VRGLP-GMRTTTSASPDTSF 375
W D + + + Q V G P G T +
Sbjct: 391 HCTSPSSPWLDWSSHNVKCSNPQITEILTVSGPPEGGTRVTIHGVNLGL 439
>ref|NP_062533.1| plexin 6 [Mus musculus]
gb|AAF22147.1|AF133093_2 (AF133093) plexin 6 [Mus musculus]
Length = 1892
Score = 121 bits (302), Expect = 1e-26
Identities = 19/131 (14%), Positives = 40/131 (30%), Gaps = 7/131 (5%)
Query: 231 IVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIEL--DPS 288
V A + ++ + +Q + ++ +I ++ D
Sbjct: 379 AVAALQTDGHTIAFLGDTQGQLHKVFLNSSHGQVYHSQQVGPPGSAISPDLLVDSNGDHL 438
Query: 289 KVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQ----EWDG 344
V + V+ + C Q +C C+ + C WC + RC+ + R W
Sbjct: 439 YVLTAQQVDRILVAACPQFPNCTTCLQA-RDPLCGWCILQGRCTRRGECGRAAQPNHWLW 497
Query: 345 TMGCAQEAEGQ 355
+ Q
Sbjct: 498 SYEDNHCPYIQ 508
>emb|CAB56222.1| (AJ011415) plexin-B1/SEP receptor [Homo sapiens]
Length = 1952
Score = 119 bits (296), Expect = 8e-26
Identities = 22/125 (17%), Positives = 43/125 (33%), Gaps = 7/125 (5%)
Query: 231 IVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRI--ELDPS 288
V E ++ + SQ + +P + ++ +
Sbjct: 407 AVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHL 466
Query: 289 KVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYR----QEWDG 344
V + S + P+ +C QH C +C+ + C WC +L RCS + R ++W
Sbjct: 467 YVMTQSTLLKVPVASCAQHLDCASCL-AHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLW 525
Query: 345 TMGCA 349
+
Sbjct: 526 SFQPE 530
Score = 35.6 bits (81), Expect = 1.1
Identities = 23/112 (20%), Positives = 33/112 (28%), Gaps = 11/112 (9%)
Query: 307 HRSCDACMSSDLTFNCSWCHVLQ-RCSSGFDRYRQEWDGTMGCA-----QEAEGQDVRGL 360
H C C ++ + C WC + RC + E T A E V
Sbjct: 843 HGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPV--- 899
Query: 361 PGMRTTTSASPDTSFSPYD--GDLTTTSSSLFIDSLTTEDDTKLNPYAGGDG 410
G T + D G +T +D+ E + L G G
Sbjct: 900 DGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASG 951
Score = 34.4 bits (78), Expect = 2.4
Identities = 11/50 (22%), Positives = 16/50 (32%), Gaps = 2/50 (4%)
Query: 310 CDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTMGCAQEAEGQDVRG 359
C AC+SS C+WC C+ + + RG
Sbjct: 641 CQACVSSRWG--CNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARG 688
>dbj|BAA86520.1| (AB033032) KIAA1206 protein [Homo sapiens]
Length = 1912
Score = 118 bits (294), Expect = 1e-25
Identities = 22/152 (14%), Positives = 42/152 (27%), Gaps = 14/152 (9%)
Query: 231 IVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRI--ELDPS 288
V A + + + +Q + +I +
Sbjct: 402 AVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGSHL 461
Query: 289 KVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQ----EWDG 344
V + V+ P+ C Q C +C+ + C WC + RC+ R +W
Sbjct: 462 YVLTAHQVDRIPVAACPQFPDCASCLQAQ-DPLCGWCVLQGRCTRKGQCGRAGQLNQWLW 520
Query: 345 TM-GCAQEAEGQDV------RGLPGMRTTTSA 369
+ + Q + R G T +
Sbjct: 521 SYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVP 552
>ref|NP_005384.1| plexin B3; plexin 6; plexin-B3 [Homo sapiens]
gb|AAF74510.1| (U52111) plexin-related protein [Homo sapiens]
Length = 1891
Score = 118 bits (294), Expect = 1e-25
Identities = 22/152 (14%), Positives = 42/152 (27%), Gaps = 14/152 (9%)
Query: 231 IVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRI--ELDPS 288
V A + + + +Q + +I +
Sbjct: 381 AVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGSHL 440
Query: 289 KVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQ----EWDG 344
V + V+ P+ C Q C +C+ + C WC + RC+ R +W
Sbjct: 441 YVLTAHQVDRIPVAACPQFPDCASCLQAQ-DPLCGWCVLQGRCTRKGQCGRAGQLNQWLW 499
Query: 345 TM-GCAQEAEGQDV------RGLPGMRTTTSA 369
+ + Q + R G T +
Sbjct: 500 SYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVP 531
>gb|AAG01376.1|AF149019_1 (AF149019) plexin-B3 [Homo sapiens]
Length = 1909
Score = 118 bits (294), Expect = 1e-25
Identities = 22/152 (14%), Positives = 42/152 (27%), Gaps = 14/152 (9%)
Query: 231 IVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRI--ELDPS 288
V A + + + +Q + +I +
Sbjct: 399 AVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGSHL 458
Query: 289 KVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQ----EWDG 344
V + V+ P+ C Q C +C+ + C WC + RC+ R +W
Sbjct: 459 YVLTAHQVDRIPVAACPQFPDCASCLQAQ-DPLCGWCVLQGRCTRKGQCGRAGQLNQWLW 517
Query: 345 TM-GCAQEAEGQDV------RGLPGMRTTTSA 369
+ + Q + R G T +
Sbjct: 518 SYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVP 549
>ref|NP_002664.1| plexin B1; plexin 5; KIAA0407 protein [Homo sapiens]
emb|CAB57277.1| (X87904) semaphorin receptor [Homo sapiens]
Length = 2135
Score = 118 bits (293), Expect = 1e-25
Identities = 22/125 (17%), Positives = 43/125 (33%), Gaps = 7/125 (5%)
Query: 231 IVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRI--ELDPS 288
V E ++ + SQ + +P + ++ +
Sbjct: 407 AVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHL 466
Query: 289 KVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYR----QEWDG 344
V + S + P+ +C QH C +C+ + C WC +L RCS + R ++W
Sbjct: 467 YVMTQSTLLKVPVASCAQHLDCASCL-AHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLW 525
Query: 345 TMGCA 349
+
Sbjct: 526 SFQPE 530
Score = 36.3 bits (83), Expect = 0.73
Identities = 16/65 (24%), Positives = 22/65 (33%), Gaps = 8/65 (12%)
Query: 310 CDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTMGCAQEAEGQDVRGLPGMRTTTSA 369
C AC+SS C+WC C+ + + RG P S
Sbjct: 641 CQACVSSRWG--CNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGP------SP 692
Query: 370 SPDTS 374
SP T+
Sbjct: 693 SPPTA 697
Score = 35.2 bits (80), Expect = 1.4
Identities = 23/112 (20%), Positives = 33/112 (28%), Gaps = 11/112 (9%)
Query: 307 HRSCDACMSSDLTFNCSWCHVLQ-RCSSGFDRYRQEWDGTMGCA-----QEAEGQDVRGL 360
H C C ++ + C WC + RC + E T A E V
Sbjct: 1026 HGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPV--- 1082
Query: 361 PGMRTTTSASPDTSFSPYD--GDLTTTSSSLFIDSLTTEDDTKLNPYAGGDG 410
G T + D G +T +D+ E + L G G
Sbjct: 1083 DGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASG 1134
>dbj|BAA23703.1| (AB007867) KIAA0407 [Homo sapiens]
Length = 2135
Score = 118 bits (293), Expect = 1e-25
Identities = 22/125 (17%), Positives = 43/125 (33%), Gaps = 7/125 (5%)
Query: 231 IVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRI--ELDPS 288
V E ++ + SQ + +P + ++ +
Sbjct: 407 AVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHL 466
Query: 289 KVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYR----QEWDG 344
V + S + P+ +C QH C +C+ + C WC +L RCS + R ++W
Sbjct: 467 YVMTQSTLLKVPVASCAQHLDCASCL-AHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLW 525
Query: 345 TMGCA 349
+
Sbjct: 526 SFQPE 530
Score = 36.3 bits (83), Expect = 0.71
Identities = 16/65 (24%), Positives = 22/65 (33%), Gaps = 8/65 (12%)
Query: 310 CDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTMGCAQEAEGQDVRGLPGMRTTTSA 369
C AC+SS C+WC C+ + + RG P S
Sbjct: 641 CQACVSSRWG--CNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGP------SP 692
Query: 370 SPDTS 374
SP T+
Sbjct: 693 SPPTA 697
Score = 35.2 bits (80), Expect = 1.4
Identities = 23/112 (20%), Positives = 33/112 (28%), Gaps = 11/112 (9%)
Query: 307 HRSCDACMSSDLTFNCSWCHVLQ-RCSSGFDRYRQEWDGTMGCA-----QEAEGQDVRGL 360
H C C ++ + C WC + RC + E T A E V
Sbjct: 1026 HGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPV--- 1082
Query: 361 PGMRTTTSASPDTSFSPYD--GDLTTTSSSLFIDSLTTEDDTKLNPYAGGDG 410
G T + D G +T +D+ E + L G G
Sbjct: 1083 DGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASG 1134
>ref|NP_005413.1| tectorin alpha precursor; Tectorin, alpha [Homo sapiens]
gb|AAC26019.1| (AF055136) alpha-tectorin [Homo sapiens]
Length = 2155
Score = 116 bits (289), Expect = 4e-25
Identities = 27/133 (20%), Positives = 44/133 (32%), Gaps = 31/133 (23%)
Query: 132 ASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVIHR-------MLTATQYVAPLMANFNP 184
+S + L+ F+G P R + + G + ++ + + +VAP A+ +
Sbjct: 46 SSEIKLAIPVFFFGVPYRTVYVNNNGVVSFNVLVSQFTPESFPLTDGRAFVAPFWADVHN 105
Query: 185 GYSDN-----------------------STVVYFDNGTVFVVQWDHVYLQGWEDKGSF-T 220
G + F VF+V W+ V G T
Sbjct: 106 GIRGEIYYRETMEPAILKRATKDIRKYFKDMATFSATWVFIVTWEEVTFYGGSSTTPVNT 165
Query: 221 FQAALHHDGRIVF 233
FQA L DG F
Sbjct: 166 FQAVLVSDGSYTF 178
>emb|CAB56221.1| (AJ011414) plexin-B1/SEP receptor [Homo sapiens]
Length = 729
Score = 116 bits (288), Expect = 5e-25
Identities = 22/125 (17%), Positives = 43/125 (33%), Gaps = 7/125 (5%)
Query: 231 IVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRI--ELDPS 288
V E ++ + SQ + +P + ++ +
Sbjct: 407 AVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHL 466
Query: 289 KVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYR----QEWDG 344
V + S + P+ +C QH C +C+ + C WC +L RCS + R ++W
Sbjct: 467 YVMTQSTLLKVPVASCAQHLDCASCL-AHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLW 525
Query: 345 TMGCA 349
+
Sbjct: 526 SFQPE 530
Score = 34.0 bits (77), Expect = 3.6
Identities = 15/68 (22%), Positives = 24/68 (35%), Gaps = 5/68 (7%)
Query: 310 CDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTMGCAQEAEGQDVRGLPGMRTTTSA 369
C AC+SS C+WC C+ + Q E Q +++
Sbjct: 641 CQACVSSRWG--CNWCVWQHLCTHKASCDAGPMVASH---QVMETQQSLRALPPPSSSRP 695
Query: 370 SPDTSFSP 377
+ TS +P
Sbjct: 696 ASTTSMTP 703
>ref|NP_033373.1| tectorin alpha; [a]-tectorin [Mus musculus]
pir||T30197 alpha tectorin - mouse
emb|CAA68138.1| (X99805) alpha tectorin [Mus musculus]
Length = 2155
Score = 114 bits (284), Expect = 2e-24
Identities = 27/133 (20%), Positives = 46/133 (34%), Gaps = 31/133 (23%)
Query: 132 ASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVIHR-------MLTATQYVAPLMANF-- 182
+S + L+ F+G P R + + G + ++ + + ++AP A+
Sbjct: 46 SSEIKLAIPVFFFGVPYRTVYVNNNGVVSFNVLVSQFTPESFPLTDGRAFIAPFWADVHN 105
Query: 183 ------------NPGYSDNST---------VVYFDNGTVFVVQWDHVYLQGWEDKGSF-T 220
+P +T + F VF+V W+ V G T
Sbjct: 106 GIRGEIYYRETMDPAILRRATKDIRKYFKDMTTFSATWVFIVTWEEVTFYGGSSTTPVNT 165
Query: 221 FQAALHHDGRIVF 233
FQA L DG F
Sbjct: 166 FQAVLVSDGSYTF 178
>pir||T30811 hepatocyte growth factor receptor - Fugu rubripes
emb|CAA08917.1| (AJ009961) hepatocyte growth factor receptor [Fugu rubripes]
Length = 1425
Score = 111 bits (277), Expect = 1e-23
Identities = 20/92 (21%), Positives = 33/92 (35%), Gaps = 11/92 (11%)
Query: 290 VTSMSAVEFTPL--PTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDR----YRQEWD 343
+T+ + + PL P C +C +C+ S C WC RC+ + QE+
Sbjct: 513 LTTGNKITKVPLIGPGCDHLTTCTSCLVSSRVTECGWC--EGRCTRANQCPPSVWTQEYC 570
Query: 344 GTMGCAQEAEGQDVRGLPGMRTTTSASPDTSF 375
+ +RG T T + F
Sbjct: 571 TPVVTKVFPTSGPIRGS---TTVTMCGRNFGF 599
>dbj|BAA31595.1| (AB014520) KIAA0620 protein [Homo sapiens]
Length = 1985
Score = 109 bits (271), Expect = 6e-23
Identities = 23/162 (14%), Positives = 47/162 (28%), Gaps = 19/162 (11%)
Query: 231 IVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPS-- 288
V + + + + + M + V + +H ++ DP+
Sbjct: 533 SVAVASVNNYTAVFLGTVNGRLLKINLNESMQVVSRRVVTVAYGE--PVHHVMQFDPADS 590
Query: 289 ---KVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQE---- 341
+ + + + C H +C C+ + C WC + RC+ D
Sbjct: 591 VYLYLMTSHQMARVKVAACNVHSTCGDCVGA-ADAYCGWCALETRCTLQQDCTNSSQQHF 649
Query: 342 W-DGTMGCAQE------AEGQDVRGLPGMRTTTSASPDTSFS 376
W + G ++ DVR + S S
Sbjct: 650 WTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGSLPSLS 691
Score = 36.3 bits (83), Expect = 0.58
Identities = 10/46 (21%), Positives = 14/46 (29%), Gaps = 3/46 (6%)
Query: 307 HRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTMGCAQEA 352
H +C +C+S+ C WC C S R
Sbjct: 771 HTACTSCLSAQWP--CFWCSQQHSCVSNQSRCEAS-PNPTSPQDCP 813
>sp|Q17330|SM1A_CAEEL SEMAPHORIN 1A PRECURSOR (CESEMA)
pir||T27165 hypothetical protein Y54E5B.1 - Caenorhabditis elegans
emb|CAA21714.1| (AL032653) contains similarity to Pfam domain: PF01403 (Sema
domain), Score=669.1, E-value=7.4e-198, N=1; PF01437
(Plexin repeat), Score=37.9, E-value=7.2e-08, N=1~cDNA
EST EMBL:M89253 comes from this gene~cDNA EST yk7e2.3
comes from this gene~cDNA EST>
Length = 712
Score = 109 bits (270), Expect = 8e-23
Identities = 26/125 (20%), Positives = 40/125 (31%), Gaps = 7/125 (5%)
Query: 238 IPMSVPEISSSQHP-VKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPSKVTSMSAV 296
+ I +S +K D + S V R I + + S +
Sbjct: 432 HNYDILFIGTSDGKVLKVVEVDGNATVIQSATV-FQRGVPI-VNLLTTKESVVIVSADEI 489
Query: 297 EFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTM---GCAQEAE 353
P+ C Q SC C+ +C+W + RC G ++ M Q E
Sbjct: 490 ASLPVHNCAQQTSCSKCVQLQ-DPHCAWDSSIARCVHGGSWTGDQFIQNMVFGQSEQCPE 548
Query: 354 GQDVR 358
G VR
Sbjct: 549 GIIVR 553
>pir||T13937 plexin A - fruit fly (Drosophila melanogaster)
gb|AAD09425.1| (AF106932) plexin A [Drosophila melanogaster]
Length = 1945
Score = 104 bits (257), Expect = 3e-21
Identities = 27/163 (16%), Positives = 51/163 (30%), Gaps = 11/163 (6%)
Query: 212 GWEDKGSFTFQAALHHDGRIVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPE 271
G E + A + V A +V + +S +K + ++ I N
Sbjct: 429 GGETPITSVPVAMFNTKLTSVAATSTSGYTVVFVGTSDGFLKKVVIESSSIANEYASFAV 488
Query: 272 SRRRSIFEYHRIELD----PSKVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHV 327
I ++ D V S + V + C +++C C+ + C WC +
Sbjct: 489 DLGSEINRD--MQFDNQNLYIYVMSKTKVSKVKVFDCSDYKTCGDCLGA-RDPYCGWCSL 545
Query: 328 LQRCSSGFDRYRQE----WDGTMGCAQEAEGQDVRGLPGMRTT 366
+CS + + + + V RTT
Sbjct: 546 ENKCSPRSNCQDDANDPFYWVSYKTGKCTTITSVVPHQLQRTT 588
Score = 42.6 bits (99), Expect = 0.009
Identities = 13/30 (43%), Positives = 16/30 (53%), Gaps = 2/30 (6%)
Query: 304 CLQHRSCDACMSSDLTFNCSWCHVLQRCSS 333
C H SC C+SS+ F C WC RC+
Sbjct: 672 CSTHSSCTRCVSSE--FPCDWCVEAHRCTH 699
Score = 37.1 bits (85), Expect = 0.33
Identities = 8/29 (27%), Positives = 11/29 (37%)
Query: 309 SCDACMSSDLTFNCSWCHVLQRCSSGFDR 337
SC C++ +NC WC C
Sbjct: 837 SCGICLALSEKYNCGWCSSTNTCEVEEQC 865
>gb|AAF59394.1| (AE003846) plexA gene product [Drosophila melanogaster]
Length = 1945
Score = 104 bits (257), Expect = 3e-21
Identities = 27/163 (16%), Positives = 51/163 (30%), Gaps = 11/163 (6%)
Query: 212 GWEDKGSFTFQAALHHDGRIVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPE 271
G E + A + V A +V + +S +K + ++ I N
Sbjct: 429 GGETPITSVPVAMFNTKLTSVAATSTSGYTVVFVGTSDGFLKKVVIESSSIANEYASFAV 488
Query: 272 SRRRSIFEYHRIELD----PSKVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHV 327
I ++ D V S + V + C +++C C+ + C WC +
Sbjct: 489 DLGSEINRD--MQFDNQNLYIYVMSKTKVSKVKVFDCSDYKTCGDCLGA-RDPYCGWCSL 545
Query: 328 LQRCSSGFDRYRQE----WDGTMGCAQEAEGQDVRGLPGMRTT 366
+CS + + + + V RTT
Sbjct: 546 ENKCSPRSNCQDDANDPLYWVSYKTGKCTTITSVVPHQLQRTT 588
Score = 42.6 bits (99), Expect = 0.009
Identities = 13/30 (43%), Positives = 16/30 (53%), Gaps = 2/30 (6%)
Query: 304 CLQHRSCDACMSSDLTFNCSWCHVLQRCSS 333
C H SC C+SS+ F C WC RC+
Sbjct: 672 CSTHSSCTRCVSSE--FPCDWCVEAHRCTH 699
Score = 37.1 bits (85), Expect = 0.33
Identities = 8/29 (27%), Positives = 11/29 (37%)
Query: 309 SCDACMSSDLTFNCSWCHVLQRCSSGFDR 337
SC C++ +NC WC C
Sbjct: 837 SCGICLALSEKYNCGWCSSTNTCEVEEQC 865
>pir||T13164 plexin B - fruit fly (Drosophila melanogaster)
gb|AAD09426.1| (AF106933) plexin B [Drosophila melanogaster]
Length = 2051
Score = 99.4 bits (245), Expect = 7e-20
Identities = 22/130 (16%), Positives = 40/130 (29%), Gaps = 9/130 (6%)
Query: 218 SFTFQAALHHDG-----RIVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPES 272
T A H D + + S+ + ++ +K L ++
Sbjct: 444 PITAHALFHFDNVSVTSVTATSTTDQQHSLAFLGTNMGVIKKVLLSG-QSPGEYEEIVVD 502
Query: 273 RRRSIFEYHRIEL--DPSKVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQR 330
I + D V S + + C + +C AC+ S C WC + +R
Sbjct: 503 AGNRILPNTMMSPKKDFLYVLSQRKITKLRIEHCSVYTNCSACLES-RDPFCGWCSLEKR 561
Query: 331 CSSGFDRYRQ 340
C+ R
Sbjct: 562 CTVRSTCQRD 571
Score = 41.0 bits (95), Expect = 0.023
Identities = 10/49 (20%), Positives = 16/49 (32%), Gaps = 2/49 (4%)
Query: 304 CLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTMGCAQEA 352
C H +C C+ S C+WC +C + R +
Sbjct: 684 CSHHGNCQECLQSSWG--CNWCIFDNKCVHKSLQCRNIENAVSTVGHCP 730
Score = 40.6 bits (94), Expect = 0.029
Identities = 16/104 (15%), Positives = 26/104 (24%), Gaps = 22/104 (21%)
Query: 307 HRSCDACMSSDLTF--NCSWCHVLQRCSSGFDRYRQEWDGTMGCA-----QE--AEGQDV 357
H C C+ C+WC C + + G + +
Sbjct: 838 HPDCSLCV--TRDPKYKCAWCS--NSCVYNETCIADKNSISSGSKSAIENECPLPRIDII 893
Query: 358 RGL----PGMRTTTSASPDTSFSPYDGDLTTTSSSLFIDSLTTE 397
+ L G T + D +FI S+ E
Sbjct: 894 KPLSGPVEGGTLITIEGSNLGIREED-----VRGKIFIGSVPCE 932
>gb|AAF59374.1| (AE003845) plexB gene product [Drosophila melanogaster]
Length = 816
Score = 98.7 bits (243), Expect = 1e-19
Identities = 22/130 (16%), Positives = 40/130 (29%), Gaps = 9/130 (6%)
Query: 218 SFTFQAALHHDG-----RIVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPES 272
T A H D + + S+ + ++ +K L ++
Sbjct: 444 PITAHALFHFDNVSVTSVTATSTTDQQHSLAFLGTNMGVIKKVLLSG-QSPGEYEEIVVD 502
Query: 273 RRRSIFEYHRIEL--DPSKVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQR 330
I + D V S + + C + +C AC+ S C WC + +R
Sbjct: 503 AGNRILPNTMMSPKKDFLYVLSQRKITKLRIEHCSVYTNCSACLES-RDPFCGWCSLEKR 561
Query: 331 CSSGFDRYRQ 340
C+ R
Sbjct: 562 CTVRSTCQRD 571
Score = 41.0 bits (95), Expect = 0.027
Identities = 10/49 (20%), Positives = 16/49 (32%), Gaps = 2/49 (4%)
Query: 304 CLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTMGCAQEA 352
C H +C C+ S C+WC +C + R +
Sbjct: 684 CSHHGNCQECLQSSWG--CNWCIFDNKCVHKSLQCRNIENAVSTVGHCP 730
>gb|AAF60788.1| (AC024825) contains similarity to Pfam families PF01833 (IPT/TIG
domain, score=150.2, E=3.5e-41, N=3), PF01403 (Sema
domain, score=79.8, E=1.3e-20, N=3) and PF01437 (Plexin
repeat, score=66.6, E=5.3e-16, N=3) [Caenorhabditis
elegans]
Length = 1944
Score = 87.8 bits (215), Expect = 2e-16
Identities = 20/136 (14%), Positives = 39/136 (27%), Gaps = 9/136 (6%)
Query: 231 IVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELD--PS 288
+ +V + + + L ++ + I D
Sbjct: 439 AIAINTTRSSTVAFVGTQGGQLHKILIESKRSAEKYATEMLTDNEPILSDMEFGGDGKHV 498
Query: 289 KVTSMSAVEFTPLPTCLQHRS-CDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTMG 347
+ + S V P C + CD C+SS C WC C+ R+ + G
Sbjct: 499 YILTPSKVIKMPTSRCEALSTQCDTCLSS-RDPYCGWCVSNNHCTQEESCEREVPHTSRG 557
Query: 348 -----CAQEAEGQDVR 358
++ + V+
Sbjct: 558 WLDFQNSKCPRIRSVK 573
Score = 46.5 bits (109), Expect = 5e-04
Identities = 21/100 (21%), Positives = 31/100 (31%), Gaps = 26/100 (26%)
Query: 276 SIFEYHRIELDPSKVTSMSAVEFTPLPT-------CLQHRSCDACMSSDLTFNCSWCHVL 328
EYH P+K+ +S PL T C ++ SC C +S F C WC
Sbjct: 637 PTNEYHL----PAKLIVVSDGSKLPLATTNFSFYDCNRYTSCSTCSASQ--FPCDWCLES 690
Query: 329 QRCS----SGFDRYRQEW---------DGTMGCAQEAEGQ 355
C + +Q G ++
Sbjct: 691 NECVAGKLTEDKCRKQHIVNGLNRDGSSIRKGPSKCPHIV 730
Score = 44.5 bits (104), Expect = 0.002
Identities = 8/43 (18%), Positives = 18/43 (41%), Gaps = 2/43 (4%)
Query: 301 LPTCLQH-RSCDACMSSDLTFN-CSWCHVLQRCSSGFDRYRQE 341
+ +C +C C++ D C WC + +C+ ++
Sbjct: 838 VYSCENLATNCGRCLTLDADKYDCGWCSLDSKCARPHQCSNRQ 880
>gb|AAB19189.1| (U65007) hepatocyte growth factor receptor [Rattus norvegicus]
Length = 1382
Score = 79.2 bits (193), Expect = 9e-14
Identities = 27/152 (17%), Positives = 45/152 (28%), Gaps = 29/152 (19%)
Query: 241 SVPEISSSQHPVKTGL----------SDAFMILNP-SPDVPESRRRSIFEYHRIELDPSK 289
++ + +S+ + + + +P SP+V + Y
Sbjct: 452 TIANLGTSEGRFMQVVLSRTAHFTPHVNFLLDSHPVSPEVIVEHPSNQNGYTL------- 504
Query: 290 VTSMSAVEFTPLP--TCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDR----YRQEWD 343
V + + PL C +SC C+S+ C WCH RC + + QE
Sbjct: 505 VVTGKKITKIPLNGLGCGHFQSCSQCLSAPYFIQCGWCH--NRCVHSNECPSGTWTQEIC 562
Query: 344 GTMGCAQEAEGQDVRGLPGMRTTTSASPDTSF 375
L G T D F
Sbjct: 563 LPAVYKVFPTSAP---LEGGTMLTICGWDFGF 591
>ref|NP_032617.1| met proto-oncogene [Mus musculus]
sp|P16056|MET_MOUSE HEPATOCYTE GROWTH FACTOR RECEPTOR PRECURSOR (MET PROTO-ONCOGENE
TYROSINE KINASE) (HGF-SF RECEPTOR)
pir||S01254 hepatocyte growth factor receptor precursor - mouse
emb|CAA68680.1| (Y00671) met proto-oncogene protein precursor (AA -24 to 1355) [Mus
musculus]
Length = 1379
Score = 77.2 bits (188), Expect = 3e-13
Identities = 26/147 (17%), Positives = 42/147 (27%), Gaps = 19/147 (12%)
Query: 241 SVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPSK------VTSMS 294
++ + +S+ + + +P V I PS V +
Sbjct: 450 TIANLGTSEGRFMQVVL--SRTAHLTPHVNFLLDSHPVSPEVIVEHPSNQNGYTLVVTGK 507
Query: 295 AVEFTPLP--TCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDR----YRQEWDGTMGC 348
+ PL C +SC C+S+ C WCH +C + + QE
Sbjct: 508 KITKIPLNGLGCGHFQSCSQCLSAPYFIQCGWCH--NQCVRFDECPSGTWTQEICLPAVY 565
Query: 349 AQEAEGQDVRGLPGMRTTTSASPDTSF 375
L G T D F
Sbjct: 566 KVFPTSAP---LEGGTVLTICGWDFGF 589
>emb|CAA65582.1| (X96786) c-met [Rattus norvegicus]
Length = 1382
Score = 76.1 bits (185), Expect = 7e-13
Identities = 27/147 (18%), Positives = 41/147 (27%), Gaps = 19/147 (12%)
Query: 241 SVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPSK------VTSMS 294
++ + +S+ + + +P V I PS V +
Sbjct: 452 TIANLGTSEGRFMQVVL--SRTAHFTPHVNFLLDSYPVSPEVIVEHPSNQNGYTLVVTGK 509
Query: 295 AVEFTPLP--TCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDR----YRQEWDGTMGC 348
+ PL C +SC C+S C WCH RC + + QE
Sbjct: 510 KITKIPLNGLGCGHFQSCSQCLSPPYFIQCGWCH--NRCVHSNECPSGTWTQEICLPAVY 567
Query: 349 AQEAEGQDVRGLPGMRTTTSASPDTSF 375
L G T D F
Sbjct: 568 KVFPTSAP---LEGGTMLTICGWDFGF 591
>gb|AAA51021.1| (U15667) CeSema [Caenorhabditis elegans]
Length = 562
Score = 74.5 bits (181), Expect = 2e-12
Identities = 18/94 (19%), Positives = 29/94 (30%), Gaps = 4/94 (4%)
Query: 238 IPMSVPEISSSQHP-VKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPSKVTSMSAV 296
+ I +S +K D + S V R I + + S +
Sbjct: 435 HNYDILFIGTSDGKVLKVVEVDGNATVIQSATV-FQRGVPI-VNLLTTKESVVIVSADEI 492
Query: 297 EFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQR 330
P+ C Q SC C+ +C W + R
Sbjct: 493 ASLPVHNCAQQTSCSKCVQLQ-DPHCDWDSSIAR 525
>sp|P08581|MET_HUMAN HEPATOCYTE GROWTH FACTOR RECEPTOR PRECURSOR (MET PROTO-ONCOGENE
TYROSINE KINASE) (HGF-SF RECEPTOR)
pir||TVHUME hepatocyte growth factor receptor precursor - human
emb|CAB56793.1| (X54559) proto-oncogene [Homo sapiens]
Length = 1390
Score = 74.1 bits (180), Expect = 3e-12
Identities = 27/137 (19%), Positives = 43/137 (30%), Gaps = 22/137 (16%)
Query: 247 SSQHPVKTGLSDAFMILNP-SPDVPESRRRSIFEYHRI-ELDPSKVTSMSAVEFTPLP-- 302
S P T + + +P SP+V H + + + V + + PL
Sbjct: 468 SRSGP-STPHVNFLLDSHPVSPEVIVE--------HTLNQNGYTLVITGKKITKIPLNGL 518
Query: 303 TCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDR----YRQEWDGTMGCAQEAEGQDVR 358
C +SC C+S+ C WCH +C + + Q+
Sbjct: 519 GCRHFQSCSQCLSAPPFVQCGWCH--DKCVRSEECLSGTWTQQICLPAIYKVFPNSAP-- 574
Query: 359 GLPGMRTTTSASPDTSF 375
L G T D F
Sbjct: 575 -LEGGTRLTICGWDFGF 590
>ref|NP_000236.1| met proto-oncogene precursor [Homo sapiens]
gb|AAA59591.1| (J02958) MET proto-oncogene protein [Homo sapiens]
Length = 1408
Score = 74.1 bits (180), Expect = 3e-12
Identities = 27/137 (19%), Positives = 43/137 (30%), Gaps = 22/137 (16%)
Query: 247 SSQHPVKTGLSDAFMILNP-SPDVPESRRRSIFEYHRI-ELDPSKVTSMSAVEFTPLP-- 302
S P T + + +P SP+V H + + + V + + PL
Sbjct: 468 SRSGP-STPHVNFLLDSHPVSPEVIVE--------HTLNQNGYTLVITGKKITKIPLNGL 518
Query: 303 TCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDR----YRQEWDGTMGCAQEAEGQDVR 358
C +SC C+S+ C WCH +C + + Q+
Sbjct: 519 GCRHFQSCSQCLSAPPFVQCGWCH--DKCVRSEECLSGTWTQQICLPAIYKVFPNSAP-- 574
Query: 359 GLPGMRTTTSASPDTSF 375
L G T D F
Sbjct: 575 -LEGGTRLTICGWDFGF 590
>gb|AAB54047.1| (AC002080) receptor protein tyrosine kinase [Homo sapiens]
Length = 754
Score = 73.7 bits (179), Expect = 3e-12
Identities = 27/137 (19%), Positives = 43/137 (30%), Gaps = 22/137 (16%)
Query: 247 SSQHPVKTGLSDAFMILNP-SPDVPESRRRSIFEYHRI-ELDPSKVTSMSAVEFTPLP-- 302
S P T + + +P SP+V H + + + V + + PL
Sbjct: 468 SRSGP-STPHVNFLLDSHPVSPEVIVE--------HTLNQNGYTLVITGKKITKIPLNGL 518
Query: 303 TCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDR----YRQEWDGTMGCAQEAEGQDVR 358
C +SC C+S+ C WCH +C + + Q+
Sbjct: 519 GCRHFQSCSQCLSAPPFVQCGWCH--DKCVRSEECLSGTWTQQICLPAIYKVFPNSAP-- 574
Query: 359 GLPGMRTTTSASPDTSF 375
L G T D F
Sbjct: 575 -LEGGTRLTICGWDFGF 590
>emb|CAA58863.1| (X84044) tyrosine kinase [Gallus gallus]
Length = 1382
Score = 71.4 bits (173), Expect = 2e-11
Identities = 29/173 (16%), Positives = 49/173 (27%), Gaps = 32/173 (18%)
Query: 221 FQAALHHDGRIVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNP-----------SPDV 269
F L + + + +++ + +S+ + P SP V
Sbjct: 434 FNNILLT---SISVFTKGNLTIANLGTSEGRFMQIVVSRSEPTAPHVSFQLDSHAVSPQV 490
Query: 270 PESRRRSIFEYHRIELDPSKVTSMSAVEFTPL--PTCLQHRSCDACMSSDLTFNCSWCHV 327
+ + Y V + + PL P C +SC C+ + C WC
Sbjct: 491 VVEQSAAADGYTL-------VVTGKKITKVPLNGPGCHHFQSCSQCLLAPAFMRCGWCG- 542
Query: 328 LQRCSSGFDR----YRQEWDGTMGCAQEAEGQDVRGLPGMRTTTSASPDTSFS 376
Q+C + + QE L G T D FS
Sbjct: 543 -QQCLRAPECNGGTWTQETCLPRVYEILPSSAP---LEGGTKLTLCGWDFGFS 591
>pir||T23298 hypothetical protein K04B12.1 - Caenorhabditis elegans
emb|CAB05755.1| (Z83232) predicted using Genefinder~contains similarity to Pfam
domain: PF01437 (Plexin repeat), Score=108.3,
E-value=4.8e-29, N=3; PF01833 (IPT/TIG domain),
Score=170.0, E-value=1.3e-47, N=3~cDNA EST yk21h1.5
comes from this gene~cDNA EST yk59e11.5 co>
Length = 1806
Score = 69.1 bits (167), Expect = 9e-11
Identities = 19/71 (26%), Positives = 30/71 (41%), Gaps = 8/71 (11%)
Query: 301 LPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTMGCAQEAEGQDVRGL 360
L TC H SC C+ S + C WCH Q C++ + +Q D +
Sbjct: 484 LSTCSHHSSCTECLVS-VDPLCQWCHPTQSCTTSARCT------SPVTSQCP-IVDGDPI 535
Query: 361 PGMRTTTSASP 371
P + + S++P
Sbjct: 536 PSIVSVNSSTP 546
Score = 46.5 bits (109), Expect = 5e-04
Identities = 15/58 (25%), Positives = 24/58 (40%), Gaps = 9/58 (15%)
Query: 301 LPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWDGTMGCAQEAEGQDVR 358
+ C + +C +CMSS+ NC+WC L +CS + Q +R
Sbjct: 615 VYDCSGYGTCSSCMSSEY--NCAWCSGLHKCS--NSCG-----ALEKSKACVKIQPMR 663
Score = 37.9 bits (87), Expect = 0.24
Identities = 16/87 (18%), Positives = 26/87 (29%), Gaps = 8/87 (9%)
Query: 296 VEFTPLPTCLQHRS-CDACMSSDLTFNCSWCHVLQRCSSG--FDRYRQEWDGTMGCAQEA 352
+ L +C S C +C++ + +C WC+ CS + D E
Sbjct: 740 IANVSLYSCTNLASDCSSCLALSPSLSCGWCNRQ--CSHECHESKATAVCDPPRIDKFEP 797
Query: 353 EGQDVRGLPGMRTTTSASPDTSFSPYD 379
+ G D S D
Sbjct: 798 TSGPI---EGGTIIKIYGNDLGMSVED 821
>ref|NP_033100.1| receptor protein tyrosine kinase, c-met-related; Friend virus
susceptibility 2 [Mus musculus]
pir||I48751 protein-tyrosine kinase (EC 2.7.1.112), receptor type ron-like -
mouse
emb|CAA52754.1| (X74736) receptor tyrosine kinase [Mus musculus]
Length = 1378
Score = 67.1 bits (162), Expect = 3e-10
Identities = 18/93 (19%), Positives = 28/93 (29%), Gaps = 10/93 (10%)
Query: 292 SMSAVEFTPL--PTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDR---YRQEWDGTM 346
S V P+ P C +C C+ + C WC RC + ++Q+
Sbjct: 515 SGDQVFKVPIQGPGCRHFLTCWRCLRAQRFMGCGWCG--DRCDRQKECPGSWQQDHCPPE 572
Query: 347 GCAQEAEGQDVRGLPGMRTTTSASPDTSFSPYD 379
+RG T + P D
Sbjct: 573 ISEFYPHSGPLRGT---TRLTLCGSNFYLRPDD 602
>gb|AAC39953.1| (U65949) hepatocyte growth factor-like protein receptor [Mus
musculus]
Length = 1378
Score = 67.1 bits (162), Expect = 3e-10
Identities = 18/93 (19%), Positives = 28/93 (29%), Gaps = 10/93 (10%)
Query: 292 SMSAVEFTPL--PTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDR---YRQEWDGTM 346
S V P+ P C +C C+ + C WC RC + ++Q+
Sbjct: 515 SGDQVFKVPIQGPGCRHFLTCWRCLRAQRFMGCGWCG--DRCDRQKECPGSWQQDHCPPE 572
Query: 347 GCAQEAEGQDVRGLPGMRTTTSASPDTSFSPYD 379
+RG T + P D
Sbjct: 573 ISEFYPHSGPLRGT---TRLTLCGSNFYLRPDD 602
>pir||JC5148 hepatocyte growth factor receptor precursor - African clawed frog
dbj|BAA77764.1| (AB027411) c-met/hepatocyte growth factor receptor [Xenopus laevis]
Length = 1375
Score = 66.7 bits (161), Expect = 5e-10
Identities = 31/168 (18%), Positives = 51/168 (29%), Gaps = 23/168 (13%)
Query: 221 FQAALHHDGRIVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPE-SRRRSIFE 279
F+ L + + + +++ + +S+ + P P V R I
Sbjct: 428 FRNVLLT---SISVFTQGRLTIANLGTSEGRFMQVII--SRTGQPKPHVNFLLEARPISP 482
Query: 280 YHRI-----ELDPSKVTSMSAVEFTP--LPTCLQHRSCDACMSSDLTFNCSWCHVLQRCS 332
I E + V + + P + TC +SC C+SS NC W CS
Sbjct: 483 EIVINTASEESGYTLVNTGMQIIKVPLVVLTCGHLKSCSHCLSSPSV-NCGW--SKNHCS 539
Query: 333 SGFDRYRQEWDG----TMGCAQEAEGQDVRGLPGMRTTTSASPDTSFS 376
+ + +EW L G T D S
Sbjct: 540 TKQECLNEEWIQETCPPAVYEVFPSSAP---LEGGTQLTICGSDFVLS 584
>ref|NP_002438.1| macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
[Homo sapiens]
sp|Q04912|RON_HUMAN MACROPHAGE-STIMULATING PROTEIN RECEPTOR PRECURSOR (MSP RECEPTOR)
(P185-RON) (CDW136) (CD136 ANTIGEN)
pir||I38185 protein-tyrosine kinase (EC 2.7.1.112), receptor type ron - human
emb|CAA49634.1| (X70040) tyrosine kinase [Homo sapiens]
Length = 1400
Score = 64.8 bits (156), Expect = 2e-09
Identities = 17/109 (15%), Positives = 29/109 (26%), Gaps = 10/109 (9%)
Query: 274 RRSIFEYHRIELDPSKVTSMSAVEFTPL--PTCLQHRSCDACMSSDLTFNCSWCHVLQRC 331
+ + D S V P+ P C +C C+ + C WC C
Sbjct: 495 GQPVQRDVSRLGDHLLFASGDQVFQVPIRGPGCRHFLTCGRCLRAWHFMGCGWCG--NMC 552
Query: 332 SSGFDR---YRQEWDGTMGCAQEAEGQDVRGLPGMRTTTSASPDTSFSP 377
+ ++Q+ +RG T + P
Sbjct: 553 GQQKECPGSWQQDHCPPKLTEFHPHSGPLRGS---TRLTLCGSNFYLHP 598
>gb|AAB36537.1| (U77681) tyrosine kinase receptor [Xenopus laevis]
Length = 1369
Score = 63.2 bits (152), Expect = 6e-09
Identities = 19/138 (13%), Positives = 33/138 (23%), Gaps = 10/138 (7%)
Query: 244 EISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPSKVTSMSAVEFTPL-- 301
+ +S + + + S + D + + V +
Sbjct: 445 FLGTSVGRLLQVVLQRNSKPRTLSNFSISDTHPVSREVTRIRDSLFFITGNQVTKVNITG 504
Query: 302 PTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYR---QEWDGTMGCAQEAEGQDVR 358
P C +C C+ + CSWC C + Q +R
Sbjct: 505 PGCRHFLTCSRCLRAPRFMGCSWC--KNVCCQQGECEGECAQNTCLPSIAEFYPRTAPLR 562
Query: 359 GLPGMRTTTSASPDTSFS 376
G T D S
Sbjct: 563 ---GNTNITLCGRDFQSS 577
>pir||JC4860 protein-tyrosine kinase (EC 2.7.1.112) receptor sea-related
precursor - African clawed frog
dbj|BAA13459.1| (D87758) Xron [Xenopus laevis]
Length = 1369
Score = 61.7 bits (148), Expect = 2e-08
Identities = 19/138 (13%), Positives = 33/138 (23%), Gaps = 10/138 (7%)
Query: 244 EISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPSKVTSMSAVEFTPL-- 301
+ +S + + + S + D + + V +
Sbjct: 445 FLGTSVGRLLQVVLQRNSKPRTLSNFSISDTHPVSREVTRIRDSLFFITGNQVTKVNITG 504
Query: 302 PTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYR---QEWDGTMGCAQEAEGQDVR 358
P C +C C+ + CSWC C + Q +R
Sbjct: 505 PGCRHFLTCSRCLRAPRFMGCSWC--KNVCCQQGECEGECAQNTCLPSIVEFYPRTAPLR 562
Query: 359 GLPGMRTTTSASPDTSFS 376
G T D S
Sbjct: 563 ---GNTNITLCGRDFQSS 577
>ref|NP_038686.1| sema domain, immunoglobulin domain (Ig), transmembrane domain (TM)
and short cytoplasmic domain, (semaphorin) 4A [Mus
musculus]
sp|Q62178|SM4A_MOUSE SEMAPHORIN 4A PRECURSOR (SEMAPHORIN B) (SEMA B)
pir||I48745 semaphorin B - mouse
emb|CAA59983.1| (X85991) semaphorin B [Mus musculus]
Length = 760
Score = 58.9 bits (141), Expect = 1e-07
Identities = 14/95 (14%), Positives = 31/95 (31%), Gaps = 3/95 (3%)
Query: 240 MSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPSKVTSMSA--VE 297
V + +S P+ + ++ S ++ V + + +
Sbjct: 431 HVVMYLGTSTGPLHKAVVPQDSSAYLVEEIQLSPDSEPVRNLQLAPAQGAVFAGFSGGIW 490
Query: 298 FTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCS 332
P C + SC C+ + +C+W + CS
Sbjct: 491 RVPRANCSVYESCVDCVLA-RDPHCAWDPESRLCS 524
CPU time: 56.08 user secs. 2.79 sys. secs 58.87 total secs.
Database: nr
Posted date: Nov 26, 2000 3:50 PM
Number of letters in database: 184,238,107
Number of sequences in database: 585,527
Lambda K H
0.312 0.148 0.448
Gapped
Lambda K H
0.270 0.0518 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 153757349
Number of Sequences: 585527
Number of extensions: 6231557
Number of successful extensions: 16490
Number of sequences better than 10.0: 211
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 143
Number of HSP's that attempted gapping in prelim test: 16149
Number of HSP's gapped (non-prelim): 329
length of query: 420
length of database: 184,238,107
effective HSP length: 54
effective length of query: 366
effective length of database: 152,619,649
effective search space: 55858791534
effective search space used: 55858791534
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.2 bits)
S2: 73 (32.7 bits)