Score E
Sequences producing significant alignments: (bits) Value
ref|XP_006495.1| tumor endothelial marker 1 precursor [Homo... 312 2e-84
ref|NP_065137.1| tumor endothelial marker 1 precursor [Homo... 312 2e-84
ref|XP_009595.1| thrombomodulin [Homo sapiens] 101 4e-21
pir||THHUB thrombomodulin precursor [validated] - human >gi... 101 4e-21
ref|NP_000352.1| thrombomodulin [Homo sapiens] >gi|136170|s... 101 4e-21
sp|P06579|TRBM_BOVIN THROMBOMODULIN (FETOMODULIN) (TM) >gi|... 100 1e-20
gb|AAB27209.1| thrombomodulin [human, urine, Peptide, 468 aa] 99 3e-20
pir||T27283 hypothetical protein Y64G10A.f - Caenorhabditis... 98 7e-20
emb|CAB57911.1| (AL110498) contains similarity to Pfam doma... 98 7e-20
gb|AAB80760.1| (AF022743) thrombomodulin [Rattus norvegicus] 96 1e-19
ref|NP_033404.1| thrombomodulin [Mus musculus] >gi|136171|s... 96 1e-19
gb|AAG01572.1|AF136537_1 (AF136537) C1q/MBL/SPA receptor C1... 95 3e-19
gb|AAF80402.1|AF160978_1 (AF160978) C1qRp [Rattus norvegicus] 95 3e-19
gb|AAB49723.1| (U90121) thrombomdulin [artificial sequence] 95 4e-19
pir||S78040 fibulin, splice form C precursor - mouse 94 6e-19
pir||S34968 fibulin, splice form D precursor - mouse 94 6e-19
ref|NP_034310.1| fibulin 1; BM-90/fibulin extracellular mat... 94 6e-19
emb|CAC18105.1| (AL021578) dJ453C12.1.2 (matrilin 4) [Homo ... 94 8e-19
ref|XP_009596.1| complement component C1q receptor [Homo sa... 94 1e-18
ref|NP_036204.1| complement component C1q receptor [Homo sa... 94 1e-18
ref|XP_010044.1| fibulin 1 isoform D [Homo sapiens] 93 1e-18
ref|XP_010045.1| fibulin 1 isoform B precursor [Homo sapiens] 93 1e-18
ref|XP_010046.1| fibulin 1 isoform C precursor [Homo sapiens] 93 1e-18
ref|XP_010047.1| fibulin 1 isoform A precursor [Homo sapiens] 93 1e-18
gb|AAG17241.1|AF217999_1 (AF217999) unknown [Homo sapiens] 93 1e-18
ref|NP_006477.1| fibulin 1 isoform A precursor [Homo sapien... 93 1e-18
ref|NP_001987.1| fibulin 1 isoform A precursor [Homo sapien... 93 1e-18
ref|NP_006476.1| fibulin 1 isoform A precursor [Homo sapien... 93 1e-18
ref|NP_006478.1| fibulin 1 isoform A precursor [Homo sapien... 93 1e-18
pir||T13954 MEGF6 protein - rat >gi|3449294|dbj|BAA32462.1|... 92 2e-18
sp|O73775|FBL1_CHICK FIBULIN-1 PRECURSOR >gi|2947316|gb|AAC... 92 2e-18
gb|AAC05387.1| (AF051399) fibulin-1, isoform D precursor [G... 92 2e-18
ref|NP_034870.1| lymphocyte antigen 68 [Mus musculus] >gi|3... 92 4e-18
gb|AAD34456.1| (AF135253) fibulin-2 [Mus musculus] 91 5e-18
ref|NP_032018.1| fibulin 2 [Mus musculus] >gi|585122|sp|P37... 91 5e-18
ref|XP_003053.1| fibulin 2 precursor [Homo sapiens] 90 1e-17
emb|CAB43267.1| (AL050095) hypothetical protein [Homo sapiens] 90 1e-17
ref|NP_001989.1| fibulin 2 precursor; Fibulin-2 [Homo sapie... 90 1e-17
emb|CAB62995.1| (Z98047) dJ162H14.1 (Fibulin 1) [Homo sapiens] 89 3e-17
ref|NP_058042.1| matrilin 2 [Mus musculus] >gi|7387906|sp|O... 89 3e-17
gb|AAG25939.1|AF276425_1 (AF276425) EGF-related protein SCU... 88 4e-17
gb|AAB80944.1| (AF013751) fibulin-1 D [Danio rerio] 87 1e-16
gb|AAD41769.1|AF112153_1 (AF112153) developmental arteries ... 85 4e-16
ref|NP_035942.1| fibulin 5 [Mus musculus] >gi|9973193|sp|Q9... 85 4e-16
ref|XP_006089.1| CEGP1 protein [Homo sapiens] 83 1e-15
ref|NP_066025.1| CEGP1 protein [Homo sapiens] >gi|8052237|e... 83 1e-15
ref|NP_002371.1| matrilin 2; Human matrilin-2 precursor mRN... 82 2e-15
ref|NP_062026.1| fibulin 5 [Rattus norvegicus] >gi|4583509|... 82 2e-15
ref|XP_007402.1| fibulin 5 [Homo sapiens] 82 3e-15
emb|CAB38568.1| (AJ133490) fibulin-5 [Homo sapiens] >gi|530... 82 3e-15
>ref|XP_006495.1| tumor endothelial marker 1 precursor [Homo sapiens]
Length = 585
Score = 312 bits (790), Expect = 2e-84
Identities = 135/135 (100%), Positives = 135/135 (100%)
Query: 1 AGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE 60
AGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE
Sbjct: 54 AGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE 113
Query: 61 PGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEA 120
PGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEA
Sbjct: 114 PGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEA 173
Query: 121 DGISCSPAGAMGAQA 135
DGISCSPAGAMGAQA
Sbjct: 174 DGISCSPAGAMGAQA 188
>ref|NP_065137.1| tumor endothelial marker 1 precursor [Homo sapiens]
gb|AAG00867.1|AF279142_1 (AF279142) tumor endothelial marker 1 precursor [Homo sapiens]
Length = 757
Score = 312 bits (790), Expect = 2e-84
Identities = 135/135 (100%), Positives = 135/135 (100%)
Query: 1 AGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE 60
AGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE
Sbjct: 226 AGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE 285
Query: 61 PGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEA 120
PGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEA
Sbjct: 286 PGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEA 345
Query: 121 DGISCSPAGAMGAQA 135
DGISCSPAGAMGAQA
Sbjct: 346 DGISCSPAGAMGAQA 360
>ref|XP_009595.1| thrombomodulin [Homo sapiens]
Length = 631
Score = 101 bits (249), Expect = 4e-21
Identities = 55/125 (44%), Positives = 65/125 (52%), Gaps = 11/125 (8%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE------PGG 63
CS +NGGCEH C + G C+C G L ADGRSC Q+ C CE P
Sbjct: 301 CSVENGGCEHAC-NAIPGAPRCQCPAGAALQADGRSCTASATQS-CNDLCEHFCVPNPDQ 358
Query: 64 PQGYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVCQQMCVNYVGGFECYCSEGHELEADG 122
P YSC C G+R A D HRC D D+C + C Q CVN GGFEC+C ++L DG
Sbjct: 359 PGSYSCMCETGYRLAADQ-HRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDG 416
Query: 123 ISCSP 127
P
Sbjct: 417 ECVEP 421
Score = 78.0 bits (189), Expect = 5e-14
Identities = 53/190 (27%), Positives = 60/190 (30%), Gaps = 79/190 (41%)
Query: 2 GPLCLGTGCSPDNGGCEHECVEEVD--GHVSCRCTEGFRLAADGRSCE------------ 47
G C + N CEH CV D G SC C G+RLAAD CE
Sbjct: 333 GRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC 392
Query: 48 ------------------------------DPCAQAPCEQQCEPGGPQGYSCHCRLGFRP 77
DPC +A CE QC+P Y C C GF P
Sbjct: 393 PQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAP 452
Query: 78 AEDDPHR-----------------------------------CVDTDECQIAGVCQQMCV 102
+PHR C D DEC+ G C +C
Sbjct: 453 IPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECENGGFCSGVCH 512
Query: 103 NYVGGFECYC 112
N G FEC C
Sbjct: 513 NLPGTFECIC 522
Score = 30.9 bits (68), Expect = 7.5
Identities = 14/38 (36%), Positives = 19/38 (49%), Gaps = 1/38 (2%)
Query: 90 ECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISCS 126
+C + G C+ C G C C G L+ADG SC+
Sbjct: 300 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCT 337
>pir||THHUB thrombomodulin precursor [validated] - human
dbj|BAA00149.1| (D00210) thrombomodulin precursor [Homo sapiens]
emb|CAA29045.1| (X05495) thrombomodulin [Homo sapiens]
prf||1403353A thrombomodulin [Homo sapiens]
Length = 575
Score = 101 bits (249), Expect = 4e-21
Identities = 55/125 (44%), Positives = 65/125 (52%), Gaps = 11/125 (8%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE------PGG 63
CS +NGGCEH C + G C+C G L ADGRSC Q+ C CE P
Sbjct: 245 CSVENGGCEHAC-NAIPGAPRCQCPAGAALQADGRSCTASATQS-CNDLCEHFCVPNPDQ 302
Query: 64 PQGYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVCQQMCVNYVGGFECYCSEGHELEADG 122
P YSC C G+R A D HRC D D+C + C Q CVN GGFEC+C ++L DG
Sbjct: 303 PGSYSCMCETGYRLAADQ-HRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDG 360
Query: 123 ISCSP 127
P
Sbjct: 361 ECVEP 365
Score = 78.0 bits (189), Expect = 5e-14
Identities = 53/190 (27%), Positives = 60/190 (30%), Gaps = 79/190 (41%)
Query: 2 GPLCLGTGCSPDNGGCEHECVEEVD--GHVSCRCTEGFRLAADGRSCE------------ 47
G C + N CEH CV D G SC C G+RLAAD CE
Sbjct: 277 GRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC 336
Query: 48 ------------------------------DPCAQAPCEQQCEPGGPQGYSCHCRLGFRP 77
DPC +A CE QC+P Y C C GF P
Sbjct: 337 PQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAP 396
Query: 78 AEDDPHR-----------------------------------CVDTDECQIAGVCQQMCV 102
+PHR C D DEC+ G C +C
Sbjct: 397 IPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECENGGFCSGVCH 456
Query: 103 NYVGGFECYC 112
N G FEC C
Sbjct: 457 NLPGTFECIC 466
Score = 30.9 bits (68), Expect = 7.5
Identities = 14/38 (36%), Positives = 19/38 (49%), Gaps = 1/38 (2%)
Query: 90 ECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISCS 126
+C + G C+ C G C C G L+ADG SC+
Sbjct: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCT 281
>ref|NP_000352.1| thrombomodulin [Homo sapiens]
sp|P07204|TRBM_HUMAN THROMBOMODULIN PRECURSOR (FETOMODULIN) (TM) (CD141 ANTIGEN)
gb|AAB59508.1| (M16552) thrombomodulin [Homo sapiens]
gb|AAA61175.1| (J02973) thrombomodulin precursor [Homo sapiens]
emb|CAB51954.1| (AL049651) dJ753D10.2 (thrombomodulin) [Homo sapiens]
gb|AAD49735.1|AF169484_1 (AF169484) thrombomodulin precursor [Saimiri sciureus]
Length = 575
Score = 101 bits (249), Expect = 4e-21
Identities = 55/125 (44%), Positives = 65/125 (52%), Gaps = 11/125 (8%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE------PGG 63
CS +NGGCEH C + G C+C G L ADGRSC Q+ C CE P
Sbjct: 245 CSVENGGCEHAC-NAIPGAPRCQCPAGAALQADGRSCTASATQS-CNDLCEHFCVPNPDQ 302
Query: 64 PQGYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVCQQMCVNYVGGFECYCSEGHELEADG 122
P YSC C G+R A D HRC D D+C + C Q CVN GGFEC+C ++L DG
Sbjct: 303 PGSYSCMCETGYRLAADQ-HRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDG 360
Query: 123 ISCSP 127
P
Sbjct: 361 ECVEP 365
Score = 78.0 bits (189), Expect = 5e-14
Identities = 53/190 (27%), Positives = 60/190 (30%), Gaps = 79/190 (41%)
Query: 2 GPLCLGTGCSPDNGGCEHECVEEVD--GHVSCRCTEGFRLAADGRSCE------------ 47
G C + N CEH CV D G SC C G+RLAAD CE
Sbjct: 277 GRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC 336
Query: 48 ------------------------------DPCAQAPCEQQCEPGGPQGYSCHCRLGFRP 77
DPC +A CE QC+P Y C C GF P
Sbjct: 337 PQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAP 396
Query: 78 AEDDPHR-----------------------------------CVDTDECQIAGVCQQMCV 102
+PHR C D DEC+ G C +C
Sbjct: 397 IPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECENGGFCSGVCH 456
Query: 103 NYVGGFECYC 112
N G FEC C
Sbjct: 457 NLPGTFECIC 466
Score = 30.9 bits (68), Expect = 7.5
Identities = 14/38 (36%), Positives = 19/38 (49%), Gaps = 1/38 (2%)
Query: 90 ECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISCS 126
+C + G C+ C G C C G L+ADG SC+
Sbjct: 244 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCT 281
>sp|P06579|TRBM_BOVIN THROMBOMODULIN (FETOMODULIN) (TM)
pir||A25918 thrombomodulin - bovine (fragment)
gb|AAA30785.1| (M14657) thrombomodulin [Bos taurus]
Length = 356
Score = 99.8 bits (245), Expect = 1e-20
Identities = 54/123 (43%), Positives = 65/123 (51%), Gaps = 9/123 (7%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC----EDPCAQAPCEQQCEPGGPQ 65
C + GGC+HEC G +C C L ADGRSC E PC Q CE C G
Sbjct: 21 CGVERGGCQHECKGSA-GASNCLCPADAALQADGRSCGLPAEHPCHQL-CEHFCHLHGLG 78
Query: 66 GYSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQMCVNYVGGFECYCSEGHELEADGIS 124
Y+C C G++ A D HRC D D+C Q+ C Q CVN GGF+C+C G+EL DG
Sbjct: 79 NYTCICEAGYQLAADQ-HRCEDVDDCAQLPSPCPQRCVNTEGGFQCHCDTGYEL-VDGEC 136
Query: 125 CSP 127
P
Sbjct: 137 VDP 139
Score = 66.0 bits (158), Expect = 2e-10
Identities = 43/156 (27%), Positives = 53/156 (33%), Gaps = 41/156 (26%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAPCEQQCEPGGPQGY 67
C+ C CV +G C C G+ L DG + DPC CE QC+P G +
Sbjct: 103 CAQLPSPCPQRCVN-TEGGFQCHCDTGYELV-DGECVDPVDPCFDNNCEYQCQPVGRSEH 160
Query: 68 SCHCRLGFRPAEDDPHRC-----------------------------------VDTDECQ 92
C C GF P PH+C D +EC
Sbjct: 161 KCICAEGFAPVPGAPHKCQMFCNQTSCPADCDPHYPTICRCPEGYIIDEGSTCTDINECD 220
Query: 93 IAGVCQQMCVNYVGGFECYCSEGHELEAD-GISCSP 127
+C C N G +EC C L GI C P
Sbjct: 221 -TNICPGQCHNLPGTYECICGPDSALSGQIGIDCDP 255
>gb|AAB27209.1| thrombomodulin [human, urine, Peptide, 468 aa]
Length = 468
Score = 98.7 bits (242), Expect = 3e-20
Identities = 54/125 (43%), Positives = 64/125 (51%), Gaps = 11/125 (8%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE------PGG 63
CS +NGGCEH C + G C+C G L ADGRSC Q+ C CE P
Sbjct: 227 CSVENGGCEHAC-NAIPGAPRCQCPAGAALQADGRSCTASATQS-CNDLCEHFCVPNPDQ 284
Query: 64 PQGYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVCQQMCVNYVGGFECYCSEGHELEADG 122
P YSC C G+R A D HRC D D+C + C Q CV GGFEC+C ++L DG
Sbjct: 285 PGSYSCMCETGYRLAADQ-HRCEDVDDCILEPSPCPQRCVXTQGGFECHCYPNYDL-VDG 342
Query: 123 ISCSP 127
P
Sbjct: 343 ECVEP 347
Score = 78.0 bits (189), Expect = 5e-14
Identities = 53/190 (27%), Positives = 60/190 (30%), Gaps = 79/190 (41%)
Query: 2 GPLCLGTGCSPDNGGCEHECVEEVD--GHVSCRCTEGFRLAADGRSCE------------ 47
G C + N CEH CV D G SC C G+RLAAD CE
Sbjct: 259 GRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPC 318
Query: 48 ------------------------------DPCAQAPCEQQCEPGGPQGYSCHCRLGFRP 77
DPC +A CE QC+P Y C C GF P
Sbjct: 319 PQRCVXTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAP 378
Query: 78 AEDDPHR-----------------------------------CVDTDECQIAGVCQQMCV 102
+PHR C D DEC+ G C +C
Sbjct: 379 IPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECENGGFCSGVCH 438
Query: 103 NYVGGFECYC 112
N G FEC C
Sbjct: 439 NLPGTFECIC 448
Score = 30.9 bits (68), Expect = 7.5
Identities = 14/38 (36%), Positives = 19/38 (49%), Gaps = 1/38 (2%)
Query: 90 ECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISCS 126
+C + G C+ C G C C G L+ADG SC+
Sbjct: 226 DCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCT 263
>pir||T27283 hypothetical protein Y64G10A.f - Caenorhabditis elegans
Length = 1620
Score = 97.5 bits (239), Expect = 7e-20
Identities = 50/123 (40%), Positives = 65/123 (52%), Gaps = 7/123 (5%)
Query: 8 TGCSPDNGGCEHECVEEVDGHV-SCRCTEGFRLAADGRSCE--DPCA--QAPCEQQCEPG 62
T CS DNGGCEHEC + +G CRC GF+L+ + RSC+ DPC + C+ C
Sbjct: 200 TSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNN 259
Query: 63 GPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADG 122
+ C C GF + D CVD DEC C+ C N G + C C EG++L DG
Sbjct: 260 HGRA-QCQCYPGFHLSYDR-RSCVDIDECAKNNGCEHFCENVKGTYRCKCREGYQLGRDG 317
Query: 123 ISC 125
+C
Sbjct: 318 RTC 320
Score = 84.7 bits (206), Expect = 5e-16
Identities = 51/124 (41%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQ--APCEQQCEPGGPQ 65
C +NG C CV + G V C+C GFRL D ++CED C+ CEQ C
Sbjct: 429 CHENNGDCSQICVN-LAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICS-NQEG 486
Query: 66 GYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGIS 124
GY C C GF +ED H C D +EC I G C Q+C N G C C G+ L D S
Sbjct: 487 GYMCSCEPGFELSEDG-HSCHDMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKS 545
Query: 125 CSPA 128
C A
Sbjct: 546 CVAA 549
Score = 74.9 bits (181), Expect = 4e-13
Identities = 45/141 (31%), Positives = 59/141 (40%), Gaps = 26/141 (18%)
Query: 9 GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPC-----AQAP--------- 54
GC NGGC+H+C ++ DG C+C G+ LA D + C D A+AP
Sbjct: 326 GCQVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDNISTVIHARAPRLWDSYETV 385
Query: 55 ---------CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQMCVNY 104
C + C C C G+ D C D +EC + G C Q+CVN
Sbjct: 386 TCVTPTDLTCHKLCMHLDSGHVQCFCDDGYELI--DSKFCQDINECHENNGDCSQICVNL 443
Query: 105 VGGFECYCSEGHELEADGISC 125
G EC C G L D +C
Sbjct: 444 AGSVECQCKPGFRLMKDRKTC 464
Score = 72.2 bits (174), Expect = 3e-12
Identities = 44/125 (35%), Positives = 54/125 (43%), Gaps = 10/125 (8%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA--QAPCEQQCEPGGPQ 65
C +NGGCEHECV + G CRC GF L+ DG +C D CA C +C P
Sbjct: 120 CMANNGGCEHECVNTI-GTYYCRCWPGFELSGDGNTCSDIDECAVSNGGCSDRCV-NSPG 177
Query: 66 GYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGG--FECYCSEGHELEADG 122
G+ C C D C C G C+ C N G + C C G +L +
Sbjct: 178 GFRCDCPSDLY-LHADGRTCGKVTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENK 236
Query: 123 ISCSP 127
SC P
Sbjct: 237 RSCQP 241
Score = 71.4 bits (172), Expect = 5e-12
Identities = 44/123 (35%), Positives = 57/123 (45%), Gaps = 8/123 (6%)
Query: 8 TGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQ--APCEQQCEPGG 63
T +P + C C+ GHV C C +G+ L D + C+D C + C Q C
Sbjct: 386 TCVTPTDLTCHKLCMHLDSGHVQCFCDDGYELI-DSKFCQDINECHENNGDCSQICV-NL 443
Query: 64 PQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADG 122
C C+ GFR +D C D EC G C+Q+C N GG+ C C G EL DG
Sbjct: 444 AGSVECQCKPGFRLMKDRK-TCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDG 502
Query: 123 ISC 125
SC
Sbjct: 503 HSC 505
Score = 59.3 bits (141), Expect = 2e-08
Identities = 46/125 (36%), Positives = 51/125 (40%), Gaps = 16/125 (12%)
Query: 10 CSPD---NGGCEHECV--EEVDGHVSCRCTEGFRLAA---DGRSCEDPCAQAPCEQQCEP 61
CS D NGG CV E D C C GF A D C CE +C
Sbjct: 79 CSADLCHNGGT---CVPSEHNDNEQVCECPVGFTGAKCQYDANECM--ANNGGCEHECV- 132
Query: 62 GGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEA 120
Y C C GF D + C D DEC ++ G C CVN GGF C C L A
Sbjct: 133 NTIGTYYCRCWPGFE-LSGDGNTCSDIDECAVSNGGCSDRCVNSPGGFRCDCPSDLYLHA 191
Query: 121 DGISC 125
DG +C
Sbjct: 192 DGRTC 196
Score = 46.9 bits (109), Expect = 1e-04
Identities = 33/96 (34%), Positives = 42/96 (43%), Gaps = 17/96 (17%)
Query: 44 RSCEDPC---AQAPCEQQ-CEPGG---PQGYS-----CHCRLGFRPAEDDPHRCVDTDEC 91
R C C QA C C GG P ++ C C +GF A+ D +EC
Sbjct: 65 RGCSKCCLLRVQANCSADLCHNGGTCVPSEHNDNEQVCECPVGFTGAKCQ----YDANEC 120
Query: 92 QIA-GVCQQMCVNYVGGFECYCSEGHELEADGISCS 126
G C+ CVN +G + C C G EL DG +CS
Sbjct: 121 MANNGGCEHECVNTIGTYYCRCWPGFELSGDGNTCS 156
Score = 38.3 bits (87), Expect = 0.044
Identities = 44/164 (26%), Positives = 58/164 (34%), Gaps = 44/164 (26%)
Query: 2 GPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGF------RLAADGR---SCEDPCAQ 52
GP C C+ +NGG + + G CRC GF ++ +GR C++ C
Sbjct: 1443 GPTCEKI-CNCENGGT----CDRLTGQ--CRCLPGFTGMTCNQVCPEGRFGAGCKEKCRC 1495
Query: 53 A--------------------PCEQQCEPGGPQGYSC--HCRLGFRPAEDDPHRCVDTDE 90
A CEQ C P G G +C C + D C D
Sbjct: 1496 ANGHCNASSGECKCNLGFTGPSCEQSC-PSGKYGLNCTLDCECYGQARCDPVQGCCDCPP 1554
Query: 91 CQIAGVCQQMCVNYVGGF----ECYCSEGHELE-ADGISCSPAG 129
+ CQ C N G+ C C G + ADG PAG
Sbjct: 1555 GRYGSRCQFSCPNGFYGWYCSQSCSCQNGAHCDGADGRCLCPAG 1598
Score = 32.5 bits (72), Expect = 2.5
Identities = 38/138 (27%), Positives = 51/138 (36%), Gaps = 30/138 (21%)
Query: 10 CSPDNGG--CEHEC-------VEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQ--Q 58
C+P+ G C H C +E DG SC CT GF A C C Q +
Sbjct: 914 CAPNTYGPNCAHTCSCVNGAKCDESDG--SCHCTPGFYGATCSEVCPTGRFGIDCMQLCK 971
Query: 59 CEPGG---PQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEG 115
C+ G SC C G+ +C D+ G + C +C C++G
Sbjct: 972 CQNGAICDTSNGSCECAPGW-----SGKKC---DKACAPGTFGKDCSK-----KCDCADG 1018
Query: 116 -HELEADGISCSPAGAMG 132
H +DG P G G
Sbjct: 1019 MHCDPSDGECICPPGKKG 1036
Score = 31.3 bits (69), Expect = 5.7
Identities = 34/122 (27%), Positives = 44/122 (35%), Gaps = 36/122 (29%)
Query: 31 CRCTEGFRLAADGRSCEDPCAQ----APCEQ--QCEPGG---PQGYSCHCRLGFRPAE-- 79
C C G+ G CE C A CE+ +CE G P C C+ G+R +
Sbjct: 1250 CECLPGW----SGEHCEKSCVSGHYGAKCEETCECENGALCDPISGHCSCQPGWRGKKCN 1305
Query: 80 ------------DDPHRCVDTDEC-QIAGVCQQMCVNYVGGFEC--YCSEGHELEADGIS 124
RC ++ C I+G CQ C G C C +G G S
Sbjct: 1306 RPCLKGYFGRHCSQSCRCANSKSCDHISGRCQ--CPKGYAGHSCTELCPDG----TFGES 1359
Query: 125 CS 126
CS
Sbjct: 1360 CS 1361
>emb|CAB57911.1| (AL110498) contains similarity to Pfam domain: PF00008 (EGF-like
domain), Score=380.3, E-value=6.1e-111, N=34~cDNA EST
yk14g6.3 comes from this gene~cDNA EST yk14g6.5 comes
from this gene~cDNA EST yk172f7.5 comes from this
gene~cDNA EST yk145h2.5 comes>
emb|CAB60454.1| (AL117206) contains similarity to Pfam domain: PF00008 (EGF-like
domain), Score=380.3, E-value=6.1e-111, N=34~cDNA EST
yk14g6.3 comes from this gene~cDNA EST yk14g6.5 comes
from this gene~cDNA EST yk172f7.5 comes from this
gene~cDNA EST yk145h2.5 comes>
Length = 1664
Score = 97.5 bits (239), Expect = 7e-20
Identities = 50/123 (40%), Positives = 65/123 (52%), Gaps = 7/123 (5%)
Query: 8 TGCSPDNGGCEHECVEEVDGHV-SCRCTEGFRLAADGRSCE--DPCA--QAPCEQQCEPG 62
T CS DNGGCEHEC + +G CRC GF+L+ + RSC+ DPC + C+ C
Sbjct: 212 TSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNN 271
Query: 63 GPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADG 122
+ C C GF + D CVD DEC C+ C N G + C C EG++L DG
Sbjct: 272 HGRA-QCQCYPGFHLSYDR-RSCVDIDECAKNNGCEHFCENVKGTYRCKCREGYQLGRDG 329
Query: 123 ISC 125
+C
Sbjct: 330 RTC 332
Score = 89.7 bits (219), Expect = 1e-17
Identities = 48/122 (39%), Positives = 61/122 (49%), Gaps = 7/122 (5%)
Query: 9 GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQ--APCEQQCEPGGP 64
GC NGGC+H+C ++ DG C+C G+ LA D + C D C + C Q C
Sbjct: 338 GCQVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDINECHENNGDCSQIC-VNLA 396
Query: 65 QGYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVCQQMCVNYVGGFECYCSEGHELEADGI 123
C C+ GFR + D C D EC G C+Q+C N GG+ C C G EL DG
Sbjct: 397 GSVECQCKPGFRLMK-DRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGH 455
Query: 124 SC 125
SC
Sbjct: 456 SC 457
Score = 87.0 bits (212), Expect = 1e-16
Identities = 46/118 (38%), Positives = 59/118 (49%), Gaps = 8/118 (6%)
Query: 14 NGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED-----PCAQAPCEQQCEPGGPQGYS 68
N GCEH C E V G C+C EG++L DGR+CE+ C+ C G+
Sbjct: 301 NNGCEHFC-ENVKGTYRCKCREGYQLGRDGRTCEEMLGGCQVGNGGCQHDCYDQPDGGHV 359
Query: 69 CHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
C CR G+ A +D C D +EC + G C Q+CVN G EC C G L D +C
Sbjct: 360 CKCRNGYILA-NDQKLCHDINECHENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTC 416
Score = 84.7 bits (206), Expect = 5e-16
Identities = 51/124 (41%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA--QAPCEQQCEPGGPQ 65
C +NG C CV + G V C+C GFRL D ++CED C+ CEQ C
Sbjct: 381 CHENNGDCSQICVN-LAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICS-NQEG 438
Query: 66 GYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVCQQMCVNYVGGFECYCSEGHELEADGIS 124
GY C C GF +ED H C D +EC I G C Q+C N G C C G+ L D S
Sbjct: 439 GYMCSCEPGFELSEDG-HSCHDMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKS 497
Query: 125 CSPA 128
C A
Sbjct: 498 CVAA 501
Score = 63.6 bits (152), Expect = 1e-09
Identities = 44/137 (32%), Positives = 54/137 (39%), Gaps = 22/137 (16%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA--QAPCEQQCEPGGPQ 65
C +NGGCEHECV + G CRC GF L+ DG +C D CA C +C P
Sbjct: 120 CMANNGGCEHECVNTI-GTYYCRCWPGFELSGDGNTCSDIDECAVSNGGCSDRCV-NSPG 177
Query: 66 GYSCHCRLGFRPAEDDPHRCVD-------------TDECQIAGVCQQMCVNYVGG--FEC 110
G+ C C D C T G C+ C N G + C
Sbjct: 178 GFRCDCPSDLY-LHADGRTCGSGFHFENLILIKKVTSCSTDNGGCEHECENDSNGEFYRC 236
Query: 111 YCSEGHELEADGISCSP 127
C G +L + SC P
Sbjct: 237 RCRVGFKLSENKRSCQP 253
Score = 59.3 bits (141), Expect = 2e-08
Identities = 46/125 (36%), Positives = 51/125 (40%), Gaps = 16/125 (12%)
Query: 10 CSPD---NGGCEHECV--EEVDGHVSCRCTEGFRLAA---DGRSCEDPCAQAPCEQQCEP 61
CS D NGG CV E D C C GF A D C CE +C
Sbjct: 79 CSADLCHNGGT---CVPSEHNDNEQVCECPVGFTGAKCQYDANECM--ANNGGCEHECV- 132
Query: 62 GGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEA 120
Y C C GF D + C D DEC ++ G C CVN GGF C C L A
Sbjct: 133 NTIGTYYCRCWPGFE-LSGDGNTCSDIDECAVSNGGCSDRCVNSPGGFRCDCPSDLYLHA 191
Query: 121 DGISC 125
DG +C
Sbjct: 192 DGRTC 196
Score = 46.9 bits (109), Expect = 1e-04
Identities = 33/96 (34%), Positives = 42/96 (43%), Gaps = 17/96 (17%)
Query: 44 RSCEDPC---AQAPCEQQ-CEPGG---PQGYS-----CHCRLGFRPAEDDPHRCVDTDEC 91
R C C QA C C GG P ++ C C +GF A+ D +EC
Sbjct: 65 RGCSKCCLLRVQANCSADLCHNGGTCVPSEHNDNEQVCECPVGFTGAKCQ----YDANEC 120
Query: 92 QIA-GVCQQMCVNYVGGFECYCSEGHELEADGISCS 126
G C+ CVN +G + C C G EL DG +CS
Sbjct: 121 MANNGGCEHECVNTIGTYYCRCWPGFELSGDGNTCS 156
Score = 38.3 bits (87), Expect = 0.044
Identities = 44/164 (26%), Positives = 58/164 (34%), Gaps = 44/164 (26%)
Query: 2 GPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGF------RLAADGR---SCEDPCAQ 52
GP C C+ +NGG + + G CRC GF ++ +GR C++ C
Sbjct: 1379 GPTCEKI-CNCENGGT----CDRLTGQ--CRCLPGFTGMTCNQVCPEGRFGAGCKEKCRC 1431
Query: 53 A--------------------PCEQQCEPGGPQGYSC--HCRLGFRPAEDDPHRCVDTDE 90
A CEQ C P G G +C C + D C D
Sbjct: 1432 ANGHCNASSGECKCNLGFTGPSCEQSC-PSGKYGLNCTLDCECYGQARCDPVQGCCDCPP 1490
Query: 91 CQIAGVCQQMCVNYVGGF----ECYCSEGHELE-ADGISCSPAG 129
+ CQ C N G+ C C G + ADG PAG
Sbjct: 1491 GRYGSRCQFSCPNGFYGWYCSQSCSCQNGAHCDGADGRCLCPAG 1534
Score = 37.1 bits (84), Expect = 0.100
Identities = 42/146 (28%), Positives = 55/146 (36%), Gaps = 31/146 (21%)
Query: 2 GPLCLGTGCSPDNGG--CEHEC-------VEEVDGHVSCRCTEGFRLAADGRSCEDPCAQ 52
GPLC C+P+ G C H C +E DG SC CT GF A C
Sbjct: 840 GPLC-DQSCAPNTYGPNCAHTCSCVNGAKCDESDG--SCHCTPGFYGATCSEVCPTGRFG 896
Query: 53 APCEQ--QCEPGG---PQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGG 107
C Q +C+ G SC C G+ +C D+ G + C
Sbjct: 897 IDCMQLCKCQNGAICDTSNGSCECAPGW-----SGKKC---DKACAPGTFGKDCSK---- 944
Query: 108 FECYCSEG-HELEADGISCSPAGAMG 132
+C C++G H +DG P G G
Sbjct: 945 -KCDCADGMHCDPSDGECICPPGKKG 969
Score = 31.7 bits (70), Expect = 4.4
Identities = 37/131 (28%), Positives = 49/131 (37%), Gaps = 26/131 (19%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPG--GPQGY 67
CS NG C + DG C C GF++ + D CEQ+C G GP
Sbjct: 1514 CSCQNGA---HC-DGADGR--CLCPAGFQVKLANKKKNDLELGDKCEQKCSEGSFGP-AC 1566
Query: 68 SCHCRLGFRPAEDDPHRCV---------DTDECQIAGVCQQMCVNYVGGFECYCSEGHEL 118
S C G + +C+ +EC+ G Q C N +C C G
Sbjct: 1567 SQQCNCGKYKCDATDGKCICPVGRHGPLCEEECR-PGRYGQSCQN-----KCQCFNGATC 1620
Query: 119 EA--DGISCSP 127
+A SCSP
Sbjct: 1621 DARTGQCSCSP 1631
Score = 31.3 bits (69), Expect = 5.7
Identities = 34/122 (27%), Positives = 44/122 (35%), Gaps = 36/122 (29%)
Query: 31 CRCTEGFRLAADGRSCEDPCAQ----APCEQ--QCEPGG---PQGYSCHCRLGFRPAE-- 79
C C G+ G CE C A CE+ +CE G P C C+ G+R +
Sbjct: 1186 CECLPGW----SGEHCEKSCVSGHYGAKCEETCECENGALCDPISGHCSCQPGWRGKKCN 1241
Query: 80 ------------DDPHRCVDTDEC-QIAGVCQQMCVNYVGGFEC--YCSEGHELEADGIS 124
RC ++ C I+G CQ C G C C +G G S
Sbjct: 1242 RPCLKGYFGRHCSQSCRCANSKSCDHISGRCQ--CPKGYAGHSCTELCPDG----TFGES 1295
Query: 125 CS 126
CS
Sbjct: 1296 CS 1297
>gb|AAB80760.1| (AF022743) thrombomodulin [Rattus norvegicus]
Length = 577
Score = 96.3 bits (236), Expect = 1e-19
Identities = 52/116 (44%), Positives = 63/116 (53%), Gaps = 10/116 (8%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE------PGG 63
CS +NGGCE+ C +G C C G L ADGRSC P AQ C + C+
Sbjct: 244 CSVENGGCEYMCNRSANGP-RCVCPSGGDLQADGRSCAKPVAQL-CNELCQHFCVNNSDV 301
Query: 64 PQGYSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQMCVNYVGGFECYCSEGHEL 118
P YSC C G++ A D HRC D D+C Q C Q+C N GGFEC C +G+EL
Sbjct: 302 PGSYSCMCETGYQLAADG-HRCEDVDDCKQGPNPCPQLCSNTEGGFECRCYDGYEL 356
Score = 67.5 bits (162), Expect = 7e-11
Identities = 46/175 (26%), Positives = 55/175 (31%), Gaps = 79/175 (45%)
Query: 17 CEHECVE--EVDGHVSCRCTEGFRLAADGRSCE--------------------------- 47
C+H CV +V G SC C G++LAADG CE
Sbjct: 291 CQHFCVNNSDVPGSYSCMCETGYQLAADGHRCEDVDDCKQGPNPCPQLCSNTEGGFECRC 350
Query: 48 ---------------DPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHR-------- 84
DPC ++ CE QC+P Y+C C GF P DDP R
Sbjct: 351 YDGYELVDGECVEQLDPCFRSKCEYQCQPVNSTHYNCICAEGFAPKLDDPDRCEMFCNET 410
Query: 85 ---------------------------CVDTDECQIAGVCQQMCVNYVGGFECYC 112
C D DEC C N G +EC C
Sbjct: 411 SCPADCDPNSPSFCQCPEGFILDEGSICTDIDECSQGECLTNECRNLPGSYECIC 465
Score = 35.2 bits (79), Expect = 0.38
Identities = 14/32 (43%), Positives = 18/32 (55%)
Query: 95 GVCQQMCVNYVGGFECYCSEGHELEADGISCS 126
G C+ MC G C C G +L+ADG SC+
Sbjct: 249 GGCEYMCNRSANGPRCVCPSGGDLQADGRSCA 280
>ref|NP_033404.1| thrombomodulin [Mus musculus]
sp|P15306|TRBM_MOUSE THROMBOMODULIN PRECURSOR (FETOMODULIN) (TM)
pir||A60501 thrombomodulin precursor - mouse
emb|CAA32597.1| (X14432) thrombomodulin [Mus musculus]
Length = 577
Score = 96.3 bits (236), Expect = 1e-19
Identities = 51/116 (43%), Positives = 63/116 (53%), Gaps = 10/116 (8%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE------PGG 63
CS +NGGCE+ C + C C L ADGRSC P Q+ C + CE
Sbjct: 244 CSVENGGCEYLCNRSTN-EPRCLCPRDMDLQADGRSCARPVVQS-CNELCEHFCVSNAEV 301
Query: 64 PQGYSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQMCVNYVGGFECYCSEGHEL 118
P YSC C G++ A D HRC D D+C Q C Q+CVN GGFEC+C +G+EL
Sbjct: 302 PGSYSCMCETGYQLAADG-HRCEDVDDCKQGPNPCPQLCVNTKGGFECFCYDGYEL 356
Score = 73.0 bits (176), Expect = 2e-12
Identities = 48/175 (27%), Positives = 56/175 (31%), Gaps = 79/175 (45%)
Query: 17 CEHECVE--EVDGHVSCRCTEGFRLAADGRSCE--------------------------- 47
CEH CV EV G SC C G++LAADG CE
Sbjct: 291 CEHFCVSNAEVPGSYSCMCETGYQLAADGHRCEDVDDCKQGPNPCPQLCVNTKGGFECFC 350
Query: 48 ---------------DPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHR-------- 84
DPC + CE QC+P P Y C C GF P D+PH+
Sbjct: 351 YDGYELVDGECVELLDPCFGSNCEFQCQPVSPTDYRCICAPGFAPKPDEPHKCEMFCNET 410
Query: 85 ---------------------------CVDTDECQIAGVCQQMCVNYVGGFECYC 112
C D DEC C N+ G +EC C
Sbjct: 411 SCPADCDPNSPTVCECPEGFILDEGSVCTDIDECSQGECFTSECRNFPGSYECIC 465
>gb|AAG01572.1|AF136537_1 (AF136537) C1q/MBL/SPA receptor C1qRp precursor [Rattus norvegicus]
Length = 643
Score = 95.2 bits (233), Expect = 3e-19
Identities = 51/129 (39%), Positives = 67/129 (51%), Gaps = 19/129 (14%)
Query: 1 AGPLCLGT--GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAPCE 56
+GPLC+ GCS +NGGC+ +C E DG C C GFRL D +C +PC+ PC
Sbjct: 250 SGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPC- 308
Query: 57 QQCEPGG--------PQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGF 108
GG + Y+CHC G++ H CVD DEC+ C Q C+N GGF
Sbjct: 309 ----TGGGMCHSVPLSENYTCHCPRGYQLDSSQVH-CVDIDECE-DSPCDQECINTPGGF 362
Query: 109 ECYCSEGHE 117
C C G++
Sbjct: 363 HCECWVGYQ 371
Score = 46.9 bits (109), Expect = 1e-04
Identities = 31/120 (25%), Positives = 51/120 (41%), Gaps = 14/120 (11%)
Query: 17 CEHECVEEVDGHVSCRCTEG-FRLAADGRSCEDP---CA--QAPCEQQCEPGGPQGYSCH 70
C E + + ++ T G F + G C P C+ C+Q C GG + C
Sbjct: 224 CGDEAESKTNYYLCKETTAGVFHWGSSGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCG 283
Query: 71 CRLGFRPAEDDPHRCVDTDECQI-----AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
CR GFR DD C + C G+C + ++ + C+C G++L++ + C
Sbjct: 284 CRPGFRLL-DDLVTCASRNPCSSNPCTGGGMCHSVPLSE--NYTCHCPRGYQLDSSQVHC 340
>gb|AAF80402.1|AF160978_1 (AF160978) C1qRp [Rattus norvegicus]
Length = 643
Score = 95.2 bits (233), Expect = 3e-19
Identities = 51/129 (39%), Positives = 67/129 (51%), Gaps = 19/129 (14%)
Query: 1 AGPLCLGT--GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAPCE 56
+GPLC+ GCS +NGGC+ +C E DG C C GFRL D +C +PC+ PC
Sbjct: 250 SGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPC- 308
Query: 57 QQCEPGG--------PQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGF 108
GG + Y+CHC G++ H CVD DEC+ C Q C+N GGF
Sbjct: 309 ----TGGGMCHSVPLSENYTCHCPRGYQLDSSQVH-CVDIDECE-DSPCDQECINTPGGF 362
Query: 109 ECYCSEGHE 117
C C G++
Sbjct: 363 HCECWVGYQ 371
Score = 46.9 bits (109), Expect = 1e-04
Identities = 31/120 (25%), Positives = 51/120 (41%), Gaps = 14/120 (11%)
Query: 17 CEHECVEEVDGHVSCRCTEG-FRLAADGRSCEDP---CA--QAPCEQQCEPGGPQGYSCH 70
C E + + ++ T G F + G C P C+ C+Q C GG + C
Sbjct: 224 CGDEAESKTNYYLCKETTAGVFHWGSSGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCG 283
Query: 71 CRLGFRPAEDDPHRCVDTDECQI-----AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
CR GFR DD C + C G+C + ++ + C+C G++L++ + C
Sbjct: 284 CRPGFRLL-DDLVTCASRNPCSSNPCTGGGMCHSVPLSE--NYTCHCPRGYQLDSSQVHC 340
>gb|AAB49723.1| (U90121) thrombomdulin [artificial sequence]
Length = 461
Score = 94.8 bits (232), Expect = 4e-19
Identities = 51/116 (43%), Positives = 62/116 (52%), Gaps = 10/116 (8%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE------PGG 63
CS +NGGCE+ C +G C C G L ADGRSC P Q C + C+
Sbjct: 128 CSVENGGCEYMCNRSANGP-RCVCPSGGDLQADGRSCAKPVGQL-CNELCQHFCVNNSDV 185
Query: 64 PQGYSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQMCVNYVGGFECYCSEGHEL 118
P YSC C G++ A D HRC D D+C Q C Q+C N GGFEC C +G+EL
Sbjct: 186 PGSYSCMCETGYQLAADG-HRCEDVDDCKQGPNPCPQLCSNTEGGFECRCYDGYEL 240
Score = 67.5 bits (162), Expect = 7e-11
Identities = 46/175 (26%), Positives = 55/175 (31%), Gaps = 79/175 (45%)
Query: 17 CEHECVE--EVDGHVSCRCTEGFRLAADGRSCE--------------------------- 47
C+H CV +V G SC C G++LAADG CE
Sbjct: 175 CQHFCVNNSDVPGSYSCMCETGYQLAADGHRCEDVDDCKQGPNPCPQLCSNTEGGFECRC 234
Query: 48 ---------------DPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHR-------- 84
DPC ++ CE QC+P Y+C C GF P DDP R
Sbjct: 235 YDGYELVDGECVEQLDPCFRSKCEYQCQPVNSTHYNCICAEGFAPKLDDPDRCEMFCNET 294
Query: 85 ---------------------------CVDTDECQIAGVCQQMCVNYVGGFECYC 112
C D DEC C N G +EC C
Sbjct: 295 SCPADCDPNSPSFCQCPEGFILDEGSICTDIDECSQGECLTNECRNLPGSYECIC 349
Score = 36.0 bits (81), Expect = 0.22
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 95 GVCQQMCVNYVGGFECYCSEGHELEADGISCS-PAGAM 131
G C+ MC G C C G +L+ADG SC+ P G +
Sbjct: 133 GGCEYMCNRSANGPRCVCPSGGDLQADGRSCAKPVGQL 170
>pir||S78040 fibulin, splice form C precursor - mouse
Length = 685
Score = 94.4 bits (231), Expect = 6e-19
Identities = 46/115 (40%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E G C C+ GFRL+ DGRSCED C +PC Q+C Y C+CR G
Sbjct: 413 CGHKC-ENTPGSFHCSCSAGFRLSVDGRSCEDVNECLNSPCSQEC-ANVYGSYQCYCRRG 470
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 471 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 525
Score = 62.1 bits (148), Expect = 3e-09
Identities = 37/112 (33%), Positives = 48/112 (42%), Gaps = 13/112 (11%)
Query: 26 DGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYSCHCRLGF 75
+G +C+ C G+ L +G C D AP + C G P + C C+ GF
Sbjct: 331 EGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHHCLNSPGSFRCECKAGF 390
Query: 76 RPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
+ CVD +ECQ +C C N G F C CS G L DG SC
Sbjct: 391 Y-FDGISRTCVDINECQRYPGRLCGHKCENTPGSFHCSCSAGFRLSVDGRSC 441
Score = 45.7 bits (106), Expect = 3e-04
Identities = 38/125 (30%), Positives = 52/125 (41%), Gaps = 21/125 (16%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 69
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 186 GPCKQQCRDTGD-EVICSCFVGYQLQSDGVSCEDINECITGSHNCRLGESCINTVGSFRC 244
Query: 70 H----CRLGFRPAEDDPHRCVDTDECQIAGV--CQQ--MCVNYVGGFEC----YCSEGHE 117
C G+ ED + C D DEC+ G+ C +C N +G F C C G
Sbjct: 245 QRDSSCGTGYELTED--NNCKDIDECE-TGIHNCPPDFICQNTLGSFRCRPKLQCKSGFI 301
Query: 118 LEADG 122
+A G
Sbjct: 302 QDALG 306
Score = 39.5 bits (90), Expect = 0.020
Identities = 17/49 (34%), Positives = 26/49 (52%)
Query: 77 PAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
P E+D D C+ G C+Q C + C C G++L++DG+SC
Sbjct: 168 PDEEDQEDPYLNDRCRGGGPCKQQCRDTGDEVICSCFVGYQLQSDGVSC 216
Score = 35.2 bits (79), Expect = 0.38
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 10 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 48
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 487 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 527
>pir||S34968 fibulin, splice form D precursor - mouse
Length = 705
Score = 94.4 bits (231), Expect = 6e-19
Identities = 46/115 (40%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E G C C+ GFRL+ DGRSCED C +PC Q+C Y C+CR G
Sbjct: 413 CGHKC-ENTPGSFHCSCSAGFRLSVDGRSCEDVNECLNSPCSQEC-ANVYGSYQCYCRRG 470
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 471 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 525
Score = 62.1 bits (148), Expect = 3e-09
Identities = 37/112 (33%), Positives = 48/112 (42%), Gaps = 13/112 (11%)
Query: 26 DGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYSCHCRLGF 75
+G +C+ C G+ L +G C D AP + C G P + C C+ GF
Sbjct: 331 EGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHHCLNSPGSFRCECKAGF 390
Query: 76 RPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
+ CVD +ECQ +C C N G F C CS G L DG SC
Sbjct: 391 Y-FDGISRTCVDINECQRYPGRLCGHKCENTPGSFHCSCSAGFRLSVDGRSC 441
Score = 45.7 bits (106), Expect = 3e-04
Identities = 38/125 (30%), Positives = 52/125 (41%), Gaps = 21/125 (16%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 69
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 186 GPCKQQCRDTGD-EVICSCFVGYQLQSDGVSCEDINECITGSHNCRLGESCINTVGSFRC 244
Query: 70 H----CRLGFRPAEDDPHRCVDTDECQIAGV--CQQ--MCVNYVGGFEC----YCSEGHE 117
C G+ ED + C D DEC+ G+ C +C N +G F C C G
Sbjct: 245 QRDSSCGTGYELTED--NNCKDIDECE-TGIHNCPPDFICQNTLGSFRCRPKLQCKSGFI 301
Query: 118 LEADG 122
+A G
Sbjct: 302 QDALG 306
Score = 39.5 bits (90), Expect = 0.020
Identities = 17/49 (34%), Positives = 26/49 (52%)
Query: 77 PAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
P E+D D C+ G C+Q C + C C G++L++DG+SC
Sbjct: 168 PDEEDQEDPYLNDRCRGGGPCKQQCRDTGDEVICSCFVGYQLQSDGVSC 216
Score = 35.2 bits (79), Expect = 0.38
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 10 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 48
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 487 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 527
>ref|NP_034310.1| fibulin 1; BM-90/fibulin extracellular matrix glyroprotein [Mus
musculus]
sp|Q08879|FBL1_MOUSE FIBULIN-1 PRECURSOR (BASEMENT-MEMBRANE PROTEIN 90) (BM-90)
pir||S36441 fibulin - mouse
emb|CAA50207.1| (X70854) BM-90/fibulin [Mus musculus]
Length = 705
Score = 94.4 bits (231), Expect = 6e-19
Identities = 46/115 (40%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E G C C+ GFRL+ DGRSCED C +PC Q+C Y C+CR G
Sbjct: 413 CGHKC-ENTPGSFHCSCSAGFRLSVDGRSCEDVNECLNSPCSQEC-ANVYGSYQCYCRRG 470
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 471 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 525
Score = 62.1 bits (148), Expect = 3e-09
Identities = 37/112 (33%), Positives = 48/112 (42%), Gaps = 13/112 (11%)
Query: 26 DGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYSCHCRLGF 75
+G +C+ C G+ L +G C D AP + C G P + C C+ GF
Sbjct: 331 EGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHHCLNSPGSFRCECKAGF 390
Query: 76 RPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
+ CVD +ECQ +C C N G F C CS G L DG SC
Sbjct: 391 Y-FDGISRTCVDINECQRYPGRLCGHKCENTPGSFHCSCSAGFRLSVDGRSC 441
Score = 45.7 bits (106), Expect = 3e-04
Identities = 38/125 (30%), Positives = 52/125 (41%), Gaps = 21/125 (16%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 69
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 186 GPCKQQCRDTGD-EVICSCFVGYQLQSDGVSCEDINECITGSHNCRLGESCINTVGSFRC 244
Query: 70 H----CRLGFRPAEDDPHRCVDTDECQIAGV--CQQ--MCVNYVGGFEC----YCSEGHE 117
C G+ ED + C D DEC+ G+ C +C N +G F C C G
Sbjct: 245 QRDSSCGTGYELTED--NNCKDIDECE-TGIHNCPPDFICQNTLGSFRCRPKLQCKSGFI 301
Query: 118 LEADG 122
+A G
Sbjct: 302 QDALG 306
Score = 39.5 bits (90), Expect = 0.020
Identities = 17/49 (34%), Positives = 26/49 (52%)
Query: 77 PAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
P E+D D C+ G C+Q C + C C G++L++DG+SC
Sbjct: 168 PDEEDQEDPYLNDRCRGGGPCKQQCRDTGDEVICSCFVGYQLQSDGVSC 216
Score = 35.2 bits (79), Expect = 0.38
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 10 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 48
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 487 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 527
>emb|CAC18105.1| (AL021578) dJ453C12.1.2 (matrilin 4) [Homo sapiens]
Length = 619
Score = 94.0 bits (230), Expect = 8e-19
Identities = 49/125 (39%), Positives = 63/125 (50%), Gaps = 6/125 (4%)
Query: 4 LCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAP--CEQQCEP 61
LC C+ GC+H+CV C C G++LAAD +S D CA+ CE C
Sbjct: 213 LCGKDQCAEGGHGCQHQCVNAW-AMFHCTCNPGYKLAADNKSSIDLCAEGTHGCEHHCV- 270
Query: 62 GGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYCSEGHELEA 120
P Y CHC++GF + D C D C CQ CV+ GG C+C EGH+L+
Sbjct: 271 NSPGSYFCHCQVGF-VLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQP 329
Query: 121 DGISC 125
DG SC
Sbjct: 330 DGRSC 334
Score = 78.4 bits (190), Expect = 4e-14
Identities = 47/124 (37%), Positives = 60/124 (47%), Gaps = 12/124 (9%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCA--QAPCEQQC--EPGG 63
C+ GCEH CV G C C GF L D RSC D C+ C+ +C PGG
Sbjct: 258 CAEGTHGCEHHCVNS-PGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGG 316
Query: 64 PQGYSCHCRLGFRPAEDDPHRCVDTDECQ-IAGVCQQMCVNYVGGFECYCSEGHELEADG 122
P+ CHCR G + D C D C + C+ CV+ + C C EG +L+ADG
Sbjct: 317 PR---CHCREG-HDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADG 372
Query: 123 ISCS 126
SC+
Sbjct: 373 KSCN 376
>ref|XP_009596.1| complement component C1q receptor [Homo sapiens]
emb|CAC00597.1| (AL118508) dJ737E23.1 (EGF-like domains containing C1q/MBL/SPA
receptor (C1QR)) [Homo sapiens]
Length = 652
Score = 93.6 bits (229), Expect = 1e-18
Identities = 52/124 (41%), Positives = 66/124 (52%), Gaps = 9/124 (7%)
Query: 1 AGPLCLGT--GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAPCE 56
+GPLC+ GC+ +NGGC +C E DG C C GFRL D +C +PC+ +PC
Sbjct: 253 SGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCR 312
Query: 57 QQCE-PGGPQG--YSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCS 113
GP G Y+C C G++ + CVD DECQ C Q CVN GGF C C
Sbjct: 313 GGATCVLGPHGKNYTCRCPQGYQ-LDSSQLDCVDVDECQ-DSPCAQECVNTPGGFRCECW 370
Query: 114 EGHE 117
G+E
Sbjct: 371 VGYE 374
>ref|NP_036204.1| complement component C1q receptor [Homo sapiens]
gb|AAB53110.1| (U94333) C1qR(p) [Homo sapiens]
Length = 652
Score = 93.6 bits (229), Expect = 1e-18
Identities = 52/124 (41%), Positives = 66/124 (52%), Gaps = 9/124 (7%)
Query: 1 AGPLCLGT--GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAPCE 56
+GPLC+ GC+ +NGGC +C E DG C C GFRL D +C +PC+ +PC
Sbjct: 253 SGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCR 312
Query: 57 QQCE-PGGPQG--YSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCS 113
GP G Y+C C G++ + CVD DECQ C Q CVN GGF C C
Sbjct: 313 GGATCVLGPHGKNYTCRCPQGYQ-LDSSQLDCVDVDECQ-DSPCAQECVNTPGGFRCECW 370
Query: 114 EGHE 117
G+E
Sbjct: 371 VGYE 374
>ref|XP_010044.1| fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 93.2 bits (228), Expect = 1e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-09
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 19 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 68
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 69 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 3e-04
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 69
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 70 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 117
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 118 LEADG 122
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 0.17
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 79 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 0.38
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 10 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 48
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>ref|XP_010045.1| fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 93.2 bits (228), Expect = 1e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-09
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 19 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 68
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 69 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 3e-04
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 69
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 70 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 117
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 118 LEADG 122
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 0.17
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 79 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 0.38
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 10 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 48
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>ref|XP_010046.1| fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 93.2 bits (228), Expect = 1e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-09
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 19 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 68
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 69 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 3e-04
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 69
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 70 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 117
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 118 LEADG 122
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 0.17
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 79 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 0.38
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 10 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 48
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>ref|XP_010047.1| fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 93.2 bits (228), Expect = 1e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-09
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 19 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 68
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 69 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 3e-04
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 69
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 70 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 117
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 118 LEADG 122
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 0.17
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 79 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 0.38
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 10 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 48
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>gb|AAG17241.1|AF217999_1 (AF217999) unknown [Homo sapiens]
Length = 495
Score = 93.2 bits (228), Expect = 1e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 281 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 338
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 339 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 393
Score = 62.5 bits (149), Expect = 2e-09
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 19 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 68
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 193 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 251
Query: 69 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 252 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 309
Score = 45.7 bits (106), Expect = 3e-04
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 69
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 54 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 112
Query: 70 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 117
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 113 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 169
Query: 118 LEADG 122
+A G
Sbjct: 170 QDALG 174
Score = 36.4 bits (82), Expect = 0.17
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 79 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 41 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 84
Score = 35.2 bits (79), Expect = 0.38
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 10 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 48
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 355 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 395
>ref|NP_006477.1| fibulin 1 isoform A precursor [Homo sapiens]
sp|P37888|FBLD_HUMAN FIBULIN-1, ISOFORM D PRECURSOR
gb|AAB17099.1| (U01244) fibulin-1D [Homo sapiens]
Length = 703
Score = 93.2 bits (228), Expect = 1e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-09
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 19 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 68
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 69 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 3e-04
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 69
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 70 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 117
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 118 LEADG 122
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 0.17
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 79 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 0.38
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 10 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 48
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>ref|NP_001987.1| fibulin 1 isoform A precursor [Homo sapiens]
sp|P23144|FBLC_HUMAN FIBULIN-1, ISOFORM C PRECURSOR
pir||C36346 fibulin 1 precursor, splice form C - human
emb|CAA37772.1| (X53743) fibulin-1 C [Homo sapiens]
prf||1704259B fibulin C [Homo sapiens]
Length = 683
Score = 93.2 bits (228), Expect = 1e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-09
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 19 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 68
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 69 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 3e-04
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 69
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 70 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 117
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 118 LEADG 122
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 0.17
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 79 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 0.38
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 10 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 48
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>ref|NP_006476.1| fibulin 1 isoform A precursor [Homo sapiens]
sp|P23143|FBLB_HUMAN FIBULIN-1, ISOFORM B PRECURSOR
pir||B36346 fibulin 1 precursor, splice form B - human
emb|CAA37771.1| (X53742) fibulin-1 B [Homo sapiens]
prf||1704259A fibulin B [Homo sapiens]
Length = 601
Score = 93.2 bits (228), Expect = 1e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-09
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 19 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 68
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 69 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 3e-04
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 69
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 70 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 117
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 118 LEADG 122
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 0.17
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 79 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 0.38
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 10 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 48
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>ref|NP_006478.1| fibulin 1 isoform A precursor [Homo sapiens]
sp|P23142|FBLA_HUMAN FIBULIN-1, ISOFORM A PRECURSOR
emb|CAA37770.1| (X53741) fibulin-1 A [Homo sapiens]
Length = 566
Score = 93.2 bits (228), Expect = 1e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-09
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 19 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 68
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 69 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 3e-04
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 69
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 70 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 117
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 118 LEADG 122
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 0.17
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 79 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 0.38
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 10 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 48
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>pir||T13954 MEGF6 protein - rat
dbj|BAA32462.1| (AB011532) MEGF6 [Rattus norvegicus]
Length = 1574
Score = 92.4 bits (226), Expect = 2e-18
Identities = 46/120 (38%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGY 67
C NGGC H C G + C C G+ L D ++C D CA +PC QQ P GY
Sbjct: 338 CEAGNGGCSHGCSHTSTGPL-CTCPRGYELDEDQKTCIDIDDCANSPCCQQACANTPGGY 396
Query: 68 SCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISCS 126
C C G+R D C D DEC G C+ C N G F+C+C G+ L+ D C+
Sbjct: 397 ECSCFAGYR-LNTDGCGCEDVDECASGHGGCEHHCSNLAGSFQCFCEAGYRLDEDRRGCT 455
Score = 83.1 bits (202), Expect = 1e-15
Identities = 47/130 (36%), Positives = 64/130 (49%), Gaps = 8/130 (6%)
Query: 2 GPLCLG-TGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQ--APCE 56
G CL + C+ NGGC+H+CV+ C+C ++L DGR C PCA+ C
Sbjct: 200 GRTCLAISSCTLGNGGCQHQCVQLTVTQHRCQCRPQYQLQEDGRRCVRRSPCAEGNGGCM 259
Query: 57 QQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEG 115
C+ + C C G++ A D C D DEC + C C+N G F+C C G
Sbjct: 260 HICQELRGLAH-CGCHPGYQLAA-DRKTCEDVDECALGLAQCAHGCLNTQGSFKCVCHAG 317
Query: 116 HELEADGISC 125
+EL ADG C
Sbjct: 318 YELGADGRQC 327
Score = 78.4 bits (190), Expect = 4e-14
Identities = 49/165 (29%), Positives = 64/165 (38%), Gaps = 51/165 (30%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED---------PCAQAPCEQQ-- 58
C+ NGGC H C +E+ G C C G++LAAD ++CED CA Q
Sbjct: 251 CAEGNGGCMHIC-QELRGLAHCGCHPGYQLAADRKTCEDVDECALGLAQCAHGCLNTQGS 309
Query: 59 ----------------------------CEPGG----------PQGYSCHCRLGFRPAED 80
CE G G C C G+ ++
Sbjct: 310 FKCVCHAGYELGADGRQCYRIEMEIVNSCEAGNGGCSHGCSHTSTGPLCTCPRGYE-LDE 368
Query: 81 DPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
D C+D D+C + CQQ C N GG+EC C G+ L DG C
Sbjct: 369 DQKTCIDIDDCANSPCCQQACANTPGGYECSCFAGYRLNTDGCGC 413
Score = 55.4 bits (131), Expect = 3e-07
Identities = 39/122 (31%), Positives = 48/122 (38%), Gaps = 27/122 (22%)
Query: 5 CLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP 64
C G P GC + +VD C G CE PC C G
Sbjct: 108 CPGWSQKPGQEGC----LSDVD---ECASANG--------GCEGPC--------CNTVG- 143
Query: 65 QGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGI 123
G+ C C G++ + D C D DEC+ G CQ CVN G + C C G L DG
Sbjct: 144 -GFYCRCPPGYQ-LQGDGKTCQDVDECRAHNGGCQHRCVNTPGSYLCECKPGFRLHTDGR 201
Query: 124 SC 125
+C
Sbjct: 202 TC 203
Score = 39.5 bits (90), Expect = 0.020
Identities = 44/141 (31%), Positives = 49/141 (34%), Gaps = 31/141 (21%)
Query: 2 GPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEP 61
G C P N C H E CRC GF G SCE C + CE
Sbjct: 1172 GEACAQRCLCPTNASCHHVTGE-------CRCPPGF----TGLSCEQACQPGTFGKDCE- 1219
Query: 62 GGPQGYSCHCRLGFRPAED---DPHRCVDTDECQIAGV-CQQMCVN--YVGGFE--CYCS 113
+ C C P E DP V T G C Q C + Y G E C C
Sbjct: 1220 -----HLCQC-----PGETWACDPASGVCTCAAGYHGTGCLQRCPSGRYGPGCEHICKCL 1269
Query: 114 EGHELE-ADGISCSPAGAMGA 133
G + A G PAG +GA
Sbjct: 1270 NGGTCDPATGACYCPAGFLGA 1290
Score = 35.6 bits (80), Expect = 0.29
Identities = 41/146 (28%), Positives = 53/146 (36%), Gaps = 43/146 (29%)
Query: 2 GPLCLGT-GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQA----PCE 56
GP C+ CS +G C+ V G C C G+ +G CE C Q CE
Sbjct: 870 GPDCIHPCNCSAGHGNCD-----AVSG--LCLCEAGY----EGPRCEQSCRQGYYGPSCE 918
Query: 57 Q--QCEPGGPQGY---SCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFE-- 109
Q +CE G + +C C G+R C+ C G +
Sbjct: 919 QKCRCEHGAACDHVSGACTCPAGWR-----------------GSFCEHACPAGFFGLDCD 961
Query: 110 --CYCSEGHELEADGISC-SPAGAMG 132
C CS G +A SC PAG G
Sbjct: 962 SACNCSAGAPCDAVTGSCICPAGRWG 987
Score = 34.4 bits (77), Expect = 0.66
Identities = 44/144 (30%), Positives = 51/144 (34%), Gaps = 21/144 (14%)
Query: 3 PLCLGTGCSPDNGGCEHECVEEV---DGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQ- 58
P G GCS D CE DG SC C GF+ CE C +
Sbjct: 647 PWAFGPGCSEDCL-CEQSHTRSCNPKDG--SCSCKAGFQGERCQAECESGFFGPGCRHRC 703
Query: 59 -CEPG---GPQGYSC--HCRLGFRPAEDDPHRC-VDTDECQIAGVCQQM---CVNYVGGF 108
C+PG P C C G++ ED C V T +G C + C G
Sbjct: 704 TCQPGVACDPVSGECRTQCPPGYQ-GEDCGQECPVGTFGVNCSGSCSCVGAPCHRVTG-- 760
Query: 109 ECYCSEGHELEADGISCSPAGAMG 132
EC C G E G C P G G
Sbjct: 761 ECLCPPGKTGEDCGADC-PEGRWG 783
Score = 33.2 bits (74), Expect = 1.5
Identities = 41/149 (27%), Positives = 48/149 (31%), Gaps = 37/149 (24%)
Query: 2 GPLCL-------GTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAP 54
GP C G C P +G C G RC G G+ CE CA
Sbjct: 1302 GPSCAHVCACRQGAACDPVSGACICS-----PGKTGVRCEHGCPQDRFGKGCELKCA--- 1353
Query: 55 CEQQCEPGG---PQGYSCHCRLGFR--------PAEDDPHRCVDTDECQIAGVCQQMCVN 103
C GG SC C LG+ PA C+ CQ G C+
Sbjct: 1354 ----CRNGGLCHATNGSCSCPLGWMGPHCEHACPAGRYGAACLLECFCQNNGSCEPTT-- 1407
Query: 104 YVGGFECYCSEGHELEADGISCSPAGAMG 132
C C G +A SC P+G G
Sbjct: 1408 ----GACLCGPGFYGQACEHSC-PSGFHG 1431
>sp|O73775|FBL1_CHICK FIBULIN-1 PRECURSOR
gb|AAC05388.1| (AF051400) fibulin-1, isoform C precursor [Gallus gallus]
Length = 684
Score = 92.4 bits (226), Expect = 2e-18
Identities = 46/115 (40%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E G C CT GF+L++DGRSCED C +PC Q+C Y C+CR G
Sbjct: 412 CAHKC-ENTPGSYYCTCTMGFKLSSDGRSCEDLNECESSPCSQEC-ANVYGSYQCYCRRG 469
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
F+ ++ D C D DEC + +C C+N G F+C C S G+ L + +C
Sbjct: 470 FQLSDIDGISCEDIDECALPTGGHICSFRCINIPGSFQCTCPSTGYRLAPNARNC 524
Score = 61.7 bits (147), Expect = 4e-09
Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 13/112 (11%)
Query: 26 DGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYSCHCRLGF 75
DG +C+ C G+ L DG C D + +Q C G GP Y C C+ G+
Sbjct: 330 DGSYTCQRISPSCGRGYHLNEDGTRCVDVDECSSSDQPCGEGHVCINGPGNYRCECKSGY 389
Query: 76 RPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
+ C+D +EC+ +C C N G + C C+ G +L +DG SC
Sbjct: 390 S-FDVISRTCIDINECRRYPGRLCAHKCENTPGSYYCTCTMGFKLSSDGRSC 440
Score = 40.2 bits (92), Expect = 0.011
Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 26/122 (21%)
Query: 6 LGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQ 65
L GC G C +C + +V C C G++L DG +CED +C G
Sbjct: 177 LHDGCR-GGGPCSQQCRDTGSSYV-CSCFVGYQLQPDGVNCED-------INECITGTHS 227
Query: 66 ---GYSCHCRLG-FRPAED----------DPHRCVDTDECQI-AGVCQQ--MCVNYVGGF 108
G +C LG FR D D RC D DEC+ C +C N G F
Sbjct: 228 CGIGQTCVNTLGSFRCQRDTSCGTGYELTDDSRCKDIDECETGTHNCPPDFICQNTPGSF 287
Query: 109 EC 110
C
Sbjct: 288 RC 289
Score = 37.1 bits (84), Expect = 0.100
Identities = 15/47 (31%), Positives = 26/47 (54%), Gaps = 3/47 (6%)
Query: 79 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
++DP+ D C+ G C Q C + + C C G++L+ DG++C
Sbjct: 172 QEDPYL---HDGCRGGGPCSQQCRDTGSSYVCSCFVGYQLQPDGVNC 215
Score = 32.8 bits (73), Expect = 1.9
Identities = 26/97 (26%), Positives = 39/97 (39%), Gaps = 15/97 (15%)
Query: 10 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCEDPCAQAPCEQQCE------ 60
C+ GG C C+ + G C C + G+RLA + R+C+D C
Sbjct: 486 CALPTGGHICSFRCIN-IPGSFQCTCPSTGYRLAPNARNCQDIDECVAETHNCSFNETCF 544
Query: 61 --PGGPQGYSCHCRLGFRPAED---DPHRCVDTDECQ 92
GG + S C +R + D + C + ECQ
Sbjct: 545 NIQGGFRCLSLECPENYRKSGDTRCERLPCNENKECQ 581
>gb|AAC05387.1| (AF051399) fibulin-1, isoform D precursor [Gallus gallus]
Length = 704
Score = 92.4 bits (226), Expect = 2e-18
Identities = 46/115 (40%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E G C CT GF+L++DGRSCED C +PC Q+C Y C+CR G
Sbjct: 412 CAHKC-ENTPGSYYCTCTMGFKLSSDGRSCEDLNECESSPCSQEC-ANVYGSYQCYCRRG 469
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
F+ ++ D C D DEC + +C C+N G F+C C S G+ L + +C
Sbjct: 470 FQLSDIDGISCEDIDECALPTGGHICSFRCINIPGSFQCTCPSTGYRLAPNARNC 524
Score = 61.7 bits (147), Expect = 4e-09
Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 13/112 (11%)
Query: 26 DGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYSCHCRLGF 75
DG +C+ C G+ L DG C D + +Q C G GP Y C C+ G+
Sbjct: 330 DGSYTCQRISPSCGRGYHLNEDGTRCVDVDECSSSDQPCGEGHVCINGPGNYRCECKSGY 389
Query: 76 RPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
+ C+D +EC+ +C C N G + C C+ G +L +DG SC
Sbjct: 390 S-FDVISRTCIDINECRRYPGRLCAHKCENTPGSYYCTCTMGFKLSSDGRSC 440
Score = 40.2 bits (92), Expect = 0.011
Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 26/122 (21%)
Query: 6 LGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQ 65
L GC G C +C + +V C C G++L DG +CED +C G
Sbjct: 177 LHDGCR-GGGPCSQQCRDTGSSYV-CSCFVGYQLQPDGVNCED-------INECITGTHS 227
Query: 66 ---GYSCHCRLG-FRPAED----------DPHRCVDTDECQI-AGVCQQ--MCVNYVGGF 108
G +C LG FR D D RC D DEC+ C +C N G F
Sbjct: 228 CGIGQTCVNTLGSFRCQRDTSCGTGYELTDDSRCKDIDECETGTHNCPPDFICQNTPGSF 287
Query: 109 EC 110
C
Sbjct: 288 RC 289
Score = 37.1 bits (84), Expect = 0.100
Identities = 15/47 (31%), Positives = 26/47 (54%), Gaps = 3/47 (6%)
Query: 79 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
++DP+ D C+ G C Q C + + C C G++L+ DG++C
Sbjct: 172 QEDPYL---HDGCRGGGPCSQQCRDTGSSYVCSCFVGYQLQPDGVNC 215
Score = 32.5 bits (72), Expect = 2.5
Identities = 29/107 (27%), Positives = 42/107 (39%), Gaps = 13/107 (12%)
Query: 10 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCEDPCAQAPCEQQCE------ 60
C+ GG C C+ + G C C + G+RLA + R+C+D C
Sbjct: 486 CALPTGGHICSFRCIN-IPGSFQCTCPSTGYRLAPNARNCQDIDECVAETHNCSFNETCF 544
Query: 61 --PGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYV 105
GG + S C +R + D R TD + C+ VN V
Sbjct: 545 NIQGGFRCLSLECPENYRKS-GDTVRLEKTDTIRCIKSCRPNDVNCV 590
>ref|NP_034870.1| lymphocyte antigen 68 [Mus musculus]
gb|AAC62649.1| (AF081789) cell surface antigen AA4 [Mus musculus]
gb|AAC63274.1| (AF074856) C1q/MBL/SPA receptor C1qRp [Mus musculus]
gb|AAD47906.1| (AF099939) C1q/MBL/SP-A phagocytic receptor C1qRp [Mus musculus]
Length = 644
Score = 91.7 bits (224), Expect = 4e-18
Identities = 51/129 (39%), Positives = 66/129 (50%), Gaps = 19/129 (14%)
Query: 1 AGPLCLGT--GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAPCE 56
+GPLC+ GCS +NGGC+ +C E DG C C GFRL D +C +PC+ PC
Sbjct: 250 SGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPC- 308
Query: 57 QQCEPGG--------PQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGF 108
GG + Y+C C G++ H CVD DECQ C Q CVN +G F
Sbjct: 309 ----TGGGMCHSVPLSENYTCRCPSGYQLDSSQVH-CVDIDECQ-DSPCAQDCVNTLGSF 362
Query: 109 ECYCSEGHE 117
C C G++
Sbjct: 363 HCECWVGYQ 371
Score = 45.3 bits (105), Expect = 3e-04
Identities = 33/123 (26%), Positives = 49/123 (39%), Gaps = 14/123 (11%)
Query: 14 NGGCEHECVEEVDGHVSCRCTEG-FRLAADGRSCEDP---CA--QAPCEQQCEPGGPQGY 67
N C E E + T G F + G C P C+ C+Q C GG +
Sbjct: 221 NVACGDEAKSETHYFLCNEKTPGIFHWGSSGPLCVSPKFGCSFNNGGCQQDCFEGGDGSF 280
Query: 68 SCHCRLGFRPAEDDPHRCVDTDECQI-----AGVCQQMCVNYVGGFECYCSEGHELEADG 122
C CR GFR DD C + C G+C + ++ + C C G++L++
Sbjct: 281 RCGCRPGFRLL-DDLVTCASRNPCSSNPCTGGGMCHSVPLSE--NYTCRCPSGYQLDSSQ 337
Query: 123 ISC 125
+ C
Sbjct: 338 VHC 340
>gb|AAD34456.1| (AF135253) fibulin-2 [Mus musculus]
Length = 1221
Score = 91.3 bits (223), Expect = 5e-18
Identities = 51/114 (44%), Positives = 63/114 (54%), Gaps = 8/114 (7%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C+H C E G C C GF LAADG+ CED C C Q+C Y C+CR G
Sbjct: 950 CQHTC-ENTPGSYRCSCAAGFLLAADGKHCEDVNECETRRCSQECA-NIYGSYQCYCRQG 1007
Query: 75 FRPAEDDPHRCVDTDEC-QIAGV-CQQMCVNYVGGFECYCSE-GHELEADGISC 125
++ AED H C D DEC Q AG+ C CVN G ++C C E G+ + A+G SC
Sbjct: 1008 YQLAEDG-HTCTDIDECAQGAGILCTFRCVNVPGSYQCACPEQGYTMMANGRSC 1060
Score = 80.4 bits (195), Expect = 1e-14
Identities = 50/145 (34%), Positives = 65/145 (44%), Gaps = 24/145 (16%)
Query: 3 PLCLGTGCSPDNGGCE-----------HECVE-----EVDGHVSCRCTEGFRLAADGRSC 46
PL G G + G E H C E + G C C GF+ A GR+C
Sbjct: 877 PLVCGRGYHANEEGSECVDVNECETGVHRCGEGQLCYNLPGSYRCDCKPGFQRDAFGRTC 936
Query: 47 ED--PCAQAP---CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMC 101
D C +P C+ CE P Y C C GF A D H C D +EC+ C Q C
Sbjct: 937 IDVNECWVSPGRLCQHTCE-NTPGSYRCSCAAGFLLAADGKH-CEDVNECETRR-CSQEC 993
Query: 102 VNYVGGFECYCSEGHELEADGISCS 126
N G ++CYC +G++L DG +C+
Sbjct: 994 ANIYGSYQCYCRQGYQLAEDGHTCT 1018
Score = 54.7 bits (129), Expect = 5e-07
Identities = 35/110 (31%), Positives = 45/110 (40%), Gaps = 9/110 (8%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFR 76
C+H C+ V G C C GF L DGR+C P AP P+ S
Sbjct: 606 CQHLCINTV-GSYRCACFPGFELQGDGRTCR-PDRGAPQLDTARESAPRSESAQVSPNTI 663
Query: 77 PAE-DDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
P P+ C D G C+Q+C C C G+ + ADG+SC
Sbjct: 664 PLPVPQPNTCKDN------GPCRQVCRVVGDTAMCSCFPGYAIMADGVSC 707
Score = 48.8 bits (114), Expect = 3e-05
Identities = 33/102 (32%), Positives = 42/102 (40%), Gaps = 10/102 (9%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP---CEQQCEPGGPQGYSCHC 71
C EC + G C C +G++LA DG +C D CAQ C +C P Y C C
Sbjct: 989 CSQECAN-IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRC-VNVPGSYQCAC 1046
Query: 72 RLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFEC 110
+ C D DEC + C + C N G F C
Sbjct: 1047 PEQGYTMMANGRSCKDLDECALGTHNCSEAETCHNIQGSFRC 1088
Score = 46.9 bits (109), Expect = 1e-04
Identities = 19/43 (44%), Positives = 26/43 (60%), Gaps = 2/43 (4%)
Query: 87 DTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISCSP 127
D DEC + +CQ +C+N VG + C C G EL+ DG +C P
Sbjct: 594 DQDECLMLPGELCQHLCINTVGSYRCACFPGFELQGDGRTCRP 636
Score = 41.8 bits (96), Expect = 0.004
Identities = 39/126 (30%), Positives = 50/126 (38%), Gaps = 26/126 (20%)
Query: 13 DNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPC---------EQQCEPGG 63
DNG C C V C C G+ + ADG SCED Q C +Q C
Sbjct: 675 DNGPCRQVC-RVVGDTAMCSCFPGYAIMADGVSCED---QDECLMGTHDCSWKQFCVNTL 730
Query: 64 PQGYSCH----CRLGFRPAEDDPHRCVDTDECQI-AGVC--QQMCVNYVGGFECY----C 112
Y + C G+ + +CVD +EC C + CVN G F+CY C
Sbjct: 731 GSFYCVNHTVLCAEGY--ILNAHRKCVDINECVTDLHTCTRAEHCVNTPGSFQCYKALTC 788
Query: 113 SEGHEL 118
G+ L
Sbjct: 789 EPGYVL 794
>ref|NP_032018.1| fibulin 2 [Mus musculus]
sp|P37889|FBL2_MOUSE FIBULIN-2 PRECURSOR
pir||A49457 fibulin-2 precursor - mouse
emb|CAA53040.1| (X75285) fibulin-2 [Mus musculus]
Length = 1221
Score = 91.3 bits (223), Expect = 5e-18
Identities = 51/114 (44%), Positives = 63/114 (54%), Gaps = 8/114 (7%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C+H C E G C C GF LAADG+ CED C C Q+C Y C+CR G
Sbjct: 950 CQHTC-ENTPGSYRCSCAAGFLLAADGKHCEDVNECETRRCSQECA-NIYGSYQCYCRQG 1007
Query: 75 FRPAEDDPHRCVDTDEC-QIAGV-CQQMCVNYVGGFECYCSE-GHELEADGISC 125
++ AED H C D DEC Q AG+ C CVN G ++C C E G+ + A+G SC
Sbjct: 1008 YQLAEDG-HTCTDIDECAQGAGILCTFRCVNVPGSYQCACPEQGYTMMANGRSC 1060
Score = 80.4 bits (195), Expect = 1e-14
Identities = 50/145 (34%), Positives = 65/145 (44%), Gaps = 24/145 (16%)
Query: 3 PLCLGTGCSPDNGGCE-----------HECVE-----EVDGHVSCRCTEGFRLAADGRSC 46
PL G G + G E H C E + G C C GF+ A GR+C
Sbjct: 877 PLVCGRGYHANEEGSECVDVNECETGVHRCGEGQLCYNLPGSYRCDCKPGFQRDAFGRTC 936
Query: 47 ED--PCAQAP---CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMC 101
D C +P C+ CE P Y C C GF A D H C D +EC+ C Q C
Sbjct: 937 IDVNECWVSPGRLCQHTCE-NTPGSYRCSCAAGFLLAADGKH-CEDVNECETRR-CSQEC 993
Query: 102 VNYVGGFECYCSEGHELEADGISCS 126
N G ++CYC +G++L DG +C+
Sbjct: 994 ANIYGSYQCYCRQGYQLAEDGHTCT 1018
Score = 54.7 bits (129), Expect = 5e-07
Identities = 35/110 (31%), Positives = 45/110 (40%), Gaps = 9/110 (8%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFR 76
C+H C+ V G C C GF L DGR+C P AP P+ S
Sbjct: 606 CQHLCINTV-GSYRCACFPGFELQGDGRTCR-PDRGAPQLDTARESAPRSESAQVSPNTI 663
Query: 77 PAE-DDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
P P+ C D G C+Q+C C C G+ + ADG+SC
Sbjct: 664 PLPVPQPNTCKDN------GPCRQVCRVVGDTAMCSCFPGYAIMADGVSC 707
Score = 48.8 bits (114), Expect = 3e-05
Identities = 33/102 (32%), Positives = 42/102 (40%), Gaps = 10/102 (9%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP---CEQQCEPGGPQGYSCHC 71
C EC + G C C +G++LA DG +C D CAQ C +C P Y C C
Sbjct: 989 CSQECAN-IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRC-VNVPGSYQCAC 1046
Query: 72 RLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFEC 110
+ C D DEC + C + C N G F C
Sbjct: 1047 PEQGYTMMANGRSCKDLDECALGTHNCSEAETCHNIQGSFRC 1088
Score = 46.9 bits (109), Expect = 1e-04
Identities = 19/43 (44%), Positives = 26/43 (60%), Gaps = 2/43 (4%)
Query: 87 DTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISCSP 127
D DEC + +CQ +C+N VG + C C G EL+ DG +C P
Sbjct: 594 DQDECLMLPGELCQHLCINTVGSYRCACFPGFELQGDGRTCRP 636
Score = 41.8 bits (96), Expect = 0.004
Identities = 39/126 (30%), Positives = 50/126 (38%), Gaps = 26/126 (20%)
Query: 13 DNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPC---------EQQCEPGG 63
DNG C C V C C G+ + ADG SCED Q C +Q C
Sbjct: 675 DNGPCRQVC-RVVGDTAMCSCFPGYAIMADGVSCED---QDECLMGTHDCSWKQFCVNTL 730
Query: 64 PQGYSCH----CRLGFRPAEDDPHRCVDTDECQI-AGVC--QQMCVNYVGGFECY----C 112
Y + C G+ + +CVD +EC C + CVN G F+CY C
Sbjct: 731 GSFYCVNHTVLCAEGY--ILNAHRKCVDINECVTDLHTCTRAEHCVNTPGSFQCYKALTC 788
Query: 113 SEGHEL 118
G+ L
Sbjct: 789 EPGYVL 794
>ref|XP_003053.1| fibulin 2 precursor [Homo sapiens]
Length = 880
Score = 89.7 bits (219), Expect = 1e-17
Identities = 50/114 (43%), Positives = 63/114 (54%), Gaps = 8/114 (7%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C+H C E G C C GF LAADG+ CED C C Q+C Y C+CR G
Sbjct: 609 CQHTC-ENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECA-NIYGSYQCYCRQG 666
Query: 75 FRPAEDDPHRCVDTDEC-QIAGV-CQQMCVNYVGGFECYCSE-GHELEADGISC 125
++ AED H C D DEC Q AG+ C C+N G ++C C E G+ + A+G SC
Sbjct: 667 YQLAEDG-HTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 719
Score = 76.9 bits (186), Expect = 1e-13
Identities = 50/133 (37%), Positives = 63/133 (46%), Gaps = 17/133 (12%)
Query: 7 GTGCSPDNGGCE---HECVE-----EVDGHVSCRCTEGFRLAADGRSCED--PCAQAP-- 54
GT C D CE H C E + G C C GF+ A GR C D C +P
Sbjct: 549 GTKCV-DVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGR 607
Query: 55 -CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCS 113
C+ CE Y C C GF A D RC D +EC+ A C Q C N G ++CYC
Sbjct: 608 LCQHTCE-NTLGSYRCSCASGFLLAADGK-RCEDVNECE-AQRCSQECANIYGSYQCYCR 664
Query: 114 EGHELEADGISCS 126
+G++L DG +C+
Sbjct: 665 QGYQLAEDGHTCT 677
Score = 59.3 bits (141), Expect = 2e-08
Identities = 36/125 (28%), Positives = 51/125 (40%), Gaps = 12/125 (9%)
Query: 21 CVEEVDGHVSCR----CTEGFRLAADGRSCEDPCAQAPCEQQCEPGG-----PQGYSCHC 71
C+ V + R C G+ + DG C D +C G P Y C C
Sbjct: 523 CINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDC 582
Query: 72 RLGFRPAEDDPHRCVDTDECQIAG--VCQQMCVNYVGGFECYCSEGHELEADGISCSPAG 129
+ GF+ + C+D +EC + +CQ C N +G + C C+ G L ADG C
Sbjct: 583 KAGFQ-RDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVN 641
Query: 130 AMGAQ 134
AQ
Sbjct: 642 ECEAQ 646
Score = 57.8 bits (137), Expect = 6e-08
Identities = 34/109 (31%), Positives = 47/109 (42%), Gaps = 7/109 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFR 76
C+H C+ V G C C GF L DGR+C P P +P PQ +
Sbjct: 312 CQHLCINTV-GSYHCACFPGFSLQDDGRTCR-PEGHPP-----QPEAPQEPALKSEFSQV 364
Query: 77 PAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
+ P + C+ G C+Q+C G C C G+ + ADG+SC
Sbjct: 365 ASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSC 413
Score = 49.2 bits (115), Expect = 2e-05
Identities = 33/102 (32%), Positives = 42/102 (40%), Gaps = 10/102 (9%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP---CEQQCEPGGPQGYSCHC 71
C EC + G C C +G++LA DG +C D CAQ C +C P Y C C
Sbjct: 648 CSQECAN-IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRC-LNVPGSYQCAC 705
Query: 72 RLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFEC 110
+ C D DEC + C + C N G F C
Sbjct: 706 PEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 747
Score = 48.8 bits (114), Expect = 3e-05
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 8/106 (7%)
Query: 28 HVSCRCTEGFR--LAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRC 85
HV C EG + + R +P A + E G + S LG +
Sbjct: 243 HVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALS----LGTEAELPNSLPG 298
Query: 86 VDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISCSPAG 129
D DEC + +CQ +C+N VG + C C G L+ DG +C P G
Sbjct: 299 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEG 344
Score = 46.5 bits (108), Expect = 2e-04
Identities = 37/126 (29%), Positives = 50/126 (39%), Gaps = 20/126 (15%)
Query: 13 DNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGY 67
DNG C+ C V G C C G+ + ADG SCED C G +
Sbjct: 381 DNGPCKQVC-STVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSF 439
Query: 68 SCH----CRLGFRPAEDDPHRCVDTDECQI-AGVCQQ--MCVNYVGGFECY----CSEGH 116
C+ C G+ + + C D DEC + CQ +C N G F C C +G
Sbjct: 440 HCYKALTCEPGYALKDGE---CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF 496
Query: 117 ELEADG 122
+ +G
Sbjct: 497 LQDPEG 502
>emb|CAB43267.1| (AL050095) hypothetical protein [Homo sapiens]
Length = 576
Score = 89.7 bits (219), Expect = 1e-17
Identities = 50/114 (43%), Positives = 63/114 (54%), Gaps = 8/114 (7%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C+H C E G C C GF LAADG+ CED C C Q+C Y C+CR G
Sbjct: 305 CQHTC-ENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECA-NIYGSYQCYCRQG 362
Query: 75 FRPAEDDPHRCVDTDEC-QIAGV-CQQMCVNYVGGFECYCSE-GHELEADGISC 125
++ AED H C D DEC Q AG+ C C+N G ++C C E G+ + A+G SC
Sbjct: 363 YQLAEDG-HTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 415
Score = 76.9 bits (186), Expect = 1e-13
Identities = 50/133 (37%), Positives = 63/133 (46%), Gaps = 17/133 (12%)
Query: 7 GTGCSPDNGGCE---HECVE-----EVDGHVSCRCTEGFRLAADGRSCED--PCAQAP-- 54
GT C D CE H C E + G C C GF+ A GR C D C +P
Sbjct: 245 GTKCV-DVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGR 303
Query: 55 -CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCS 113
C+ CE Y C C GF A D RC D +EC+ A C Q C N G ++CYC
Sbjct: 304 LCQHTCE-NTLGSYRCSCASGFLLAADGK-RCEDVNECE-AQRCSQECANIYGSYQCYCR 360
Query: 114 EGHELEADGISCS 126
+G++L DG +C+
Sbjct: 361 QGYQLAEDGHTCT 373
Score = 59.3 bits (141), Expect = 2e-08
Identities = 36/125 (28%), Positives = 51/125 (40%), Gaps = 12/125 (9%)
Query: 21 CVEEVDGHVSCR----CTEGFRLAADGRSCEDPCAQAPCEQQCEPGG-----PQGYSCHC 71
C+ V + R C G+ + DG C D +C G P Y C C
Sbjct: 219 CINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDC 278
Query: 72 RLGFRPAEDDPHRCVDTDECQIAG--VCQQMCVNYVGGFECYCSEGHELEADGISCSPAG 129
+ GF+ + C+D +EC + +CQ C N +G + C C+ G L ADG C
Sbjct: 279 KAGFQ-RDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVN 337
Query: 130 AMGAQ 134
AQ
Sbjct: 338 ECEAQ 342
Score = 49.2 bits (115), Expect = 2e-05
Identities = 33/102 (32%), Positives = 42/102 (40%), Gaps = 10/102 (9%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP---CEQQCEPGGPQGYSCHC 71
C EC + G C C +G++LA DG +C D CAQ C +C P Y C C
Sbjct: 344 CSQECAN-IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRC-LNVPGSYQCAC 401
Query: 72 RLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFEC 110
+ C D DEC + C + C N G F C
Sbjct: 402 PEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 443
Score = 46.9 bits (109), Expect = 1e-04
Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 20/124 (16%)
Query: 13 DNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDP---------CAQAP-CEQQCEPG 62
DNG C+ C V G C C G+ + ADG SCED C++ C
Sbjct: 30 DNGPCKQVC-STVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSF 88
Query: 63 GPQGYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFECY----CSEG 115
++ C G+ + +CVD +EC C + CVN +G F CY C G
Sbjct: 89 YCVNHTVLCADGY--ILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPG 146
Query: 116 HELE 119
+ L+
Sbjct: 147 YALK 150
Score = 36.0 bits (81), Expect = 0.22
Identities = 14/35 (40%), Positives = 20/35 (57%)
Query: 91 CQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
C+ G C+Q+C G C C G+ + ADG+SC
Sbjct: 28 CKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSC 62
>ref|NP_001989.1| fibulin 2 precursor; Fibulin-2 [Homo sapiens]
sp|P98095|FBL2_HUMAN FIBULIN-2 PRECURSOR
pir||A55184 fibulin-2 precursor - human
emb|CAA57876.1| (X82494) fibulin-2 [Homo sapiens]
Length = 1184
Score = 89.7 bits (219), Expect = 1e-17
Identities = 50/114 (43%), Positives = 63/114 (54%), Gaps = 8/114 (7%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C+H C E G C C GF LAADG+ CED C C Q+C Y C+CR G
Sbjct: 913 CQHTC-ENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECA-NIYGSYQCYCRQG 970
Query: 75 FRPAEDDPHRCVDTDEC-QIAGV-CQQMCVNYVGGFECYCSE-GHELEADGISC 125
++ AED H C D DEC Q AG+ C C+N G ++C C E G+ + A+G SC
Sbjct: 971 YQLAEDG-HTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
Score = 75.3 bits (182), Expect = 3e-13
Identities = 47/127 (37%), Positives = 60/127 (47%), Gaps = 16/127 (12%)
Query: 13 DNGGCE---HECVE-----EVDGHVSCRCTEGFRLAADGRSCED--PCAQAP---CEQQC 59
D CE H C E + G C C GF+ A GR C D C +P C+ C
Sbjct: 858 DVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTC 917
Query: 60 EPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELE 119
E Y C C GF A D RC D +EC+ A C Q C N G ++CYC +G++L
Sbjct: 918 E-NTLGSYRCSCASGFLLAADGK-RCEDVNECE-AQRCSQECANIYGSYQCYCRQGYQLA 974
Query: 120 ADGISCS 126
DG +C+
Sbjct: 975 EDGHTCT 981
Score = 59.3 bits (141), Expect = 2e-08
Identities = 36/125 (28%), Positives = 51/125 (40%), Gaps = 12/125 (9%)
Query: 21 CVEEVDGHVSCR----CTEGFRLAADGRSCEDPCAQAPCEQQCEPGG-----PQGYSCHC 71
C+ V + R C G+ + DG C D +C G P Y C C
Sbjct: 827 CINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDC 886
Query: 72 RLGFRPAEDDPHRCVDTDECQIAG--VCQQMCVNYVGGFECYCSEGHELEADGISCSPAG 129
+ GF+ + C+D +EC + +CQ C N +G + C C+ G L ADG C
Sbjct: 887 KAGFQ-RDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVN 945
Query: 130 AMGAQ 134
AQ
Sbjct: 946 ECEAQ 950
Score = 57.8 bits (137), Expect = 6e-08
Identities = 34/109 (31%), Positives = 47/109 (42%), Gaps = 7/109 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFR 76
C+H C+ V G C C GF L DGR+C P P +P PQ +
Sbjct: 616 CQHLCINTV-GSYHCACFPGFSLQDDGRTCR-PEGHPP-----QPEAPQEPALKSEFSQV 668
Query: 77 PAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
+ P + C+ G C+Q+C G C C G+ + ADG+SC
Sbjct: 669 ASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSC 717
Score = 49.2 bits (115), Expect = 2e-05
Identities = 33/102 (32%), Positives = 42/102 (40%), Gaps = 10/102 (9%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP---CEQQCEPGGPQGYSCHC 71
C EC + G C C +G++LA DG +C D CAQ C +C P Y C C
Sbjct: 952 CSQECAN-IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRC-LNVPGSYQCAC 1009
Query: 72 RLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFEC 110
+ C D DEC + C + C N G F C
Sbjct: 1010 PEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1051
Score = 48.8 bits (114), Expect = 3e-05
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 8/106 (7%)
Query: 28 HVSCRCTEGFR--LAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRC 85
HV C EG + + R +P A + E G + S LG +
Sbjct: 547 HVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALS----LGTEAELPNSLPG 602
Query: 86 VDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISCSPAG 129
D DEC + +CQ +C+N VG + C C G L+ DG +C P G
Sbjct: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEG 648
Score = 46.5 bits (108), Expect = 2e-04
Identities = 37/126 (29%), Positives = 50/126 (39%), Gaps = 20/126 (15%)
Query: 13 DNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGY 67
DNG C+ C V G C C G+ + ADG SCED C G +
Sbjct: 685 DNGPCKQVC-STVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSF 743
Query: 68 SCH----CRLGFRPAEDDPHRCVDTDECQI-AGVCQQ--MCVNYVGGFECY----CSEGH 116
C+ C G+ + + C D DEC + CQ +C N G F C C +G
Sbjct: 744 HCYKALTCEPGYALKDGE---CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF 800
Query: 117 ELEADG 122
+ +G
Sbjct: 801 LQDPEG 806
>emb|CAB62995.1| (Z98047) dJ162H14.1 (Fibulin 1) [Homo sapiens]
Length = 554
Score = 88.5 bits (216), Expect = 3e-17
Identities = 44/115 (38%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E G C C+ GFRL+ DGRSCE + C+ +PC Q+C Y C+CR G
Sbjct: 384 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEGINECSSSPCSQEC-ANVYGSYQCYCRRG 441
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
++ ++ D C DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 442 YQLSDVDGVTCEGIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 496
Score = 57.4 bits (136), Expect = 8e-08
Identities = 39/136 (28%), Positives = 56/136 (40%), Gaps = 17/136 (12%)
Query: 5 CLGTG-CSPDNGGCE--HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCE 56
C+G C + C H C+ +G +C+ C G+ L +G C AP
Sbjct: 279 CIGINECLSISAPCPIGHTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVGVDECAPPA 337
Query: 57 QQCEPG-----GPQGYSCHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFE 109
+ C G P + C C+ G+ + CV +ECQ +C C N +G +
Sbjct: 338 EPCGKGHRCVNSPGSFRCECKTGYY-FDGISRMCVGVNECQRYPGRLCGHKCENTLGSYL 396
Query: 110 CYCSEGHELEADGISC 125
C CS G L DG SC
Sbjct: 397 CSCSVGFRLSVDGRSC 412
Score = 40.2 bits (92), Expect = 0.011
Identities = 36/125 (28%), Positives = 51/125 (40%), Gaps = 21/125 (16%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 69
G C+ +C + D V C C G++L +DG SCE C G + C
Sbjct: 157 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEGVNECITGSHSCRLGESCINTVGSFRC 215
Query: 70 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 117
C G+ ED + C DEC+ +G+ C +C N +G F C C G
Sbjct: 216 QRDSSCGTGYELTED--NSCKGIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 272
Query: 118 LEADG 122
+A G
Sbjct: 273 QDALG 277
Score = 36.4 bits (82), Expect = 0.17
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 79 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 144 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 187
Score = 33.6 bits (75), Expect = 1.1
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 7/55 (12%)
Query: 2 GPLCLGTG-CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCE--DPC 50
G C G C+ GG C + C+ + G C C + G+RLA +GR+C+ D C
Sbjct: 449 GVTCEGIDECALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQGIDEC 502
>ref|NP_058042.1| matrilin 2 [Mus musculus]
sp|O08746|MTN2_MOUSE MATRILIN-2 PRECURSOR
gb|AAC53163.1| (U69262) matrilin-2 precursor [Mus musculus]
Length = 956
Score = 88.5 bits (216), Expect = 3e-17
Identities = 48/122 (39%), Positives = 64/122 (52%), Gaps = 8/122 (6%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 65
C+ + GCEHECV +GH CRC +G+ L +G++C D CAQ CEQ C +
Sbjct: 406 CALNKPGCEHECVNTEEGHY-CRCRQGYNLDPNGKTCSRVDHCAQQDHGCEQLCL-NTEE 463
Query: 66 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHELEADGIS 124
+ C C GF DD C D C ++ C+ CVN F C C EGH L +DG +
Sbjct: 464 SFVCQCSEGFL-INDDLKTCSRADYCLLSNHGCEYSCVNTDKSFACQCPEGHVLRSDGKT 522
Query: 125 CS 126
C+
Sbjct: 523 CA 524
Score = 81.9 bits (199), Expect = 3e-15
Identities = 49/121 (40%), Positives = 61/121 (49%), Gaps = 8/121 (6%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAP--CEQQCEPGGPQ 65
C+ + GCEH CV D V C+C EG+ L DG++C +D C CE C G +
Sbjct: 529 CALGDHGCEHSCVSSEDSFV-CQCFEGYILRDDGKTCRRKDVCQDVNHGCEHLCVNSG-E 586
Query: 66 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHELEADGIS 124
Y C C GFR AED RC + C+ C+ MCVN + C CSEG L DG
Sbjct: 587 SYVCKCLEGFRLAEDGK-RCRRKNVCKSTQHGCEHMCVNNGNSYLCRCSEGFVLAEDGKH 645
Query: 125 C 125
C
Sbjct: 646 C 646
Score = 75.3 bits (182), Expect = 3e-13
Identities = 44/124 (35%), Positives = 63/124 (50%), Gaps = 8/124 (6%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCA--QAPCEQQCEPGGPQ 65
C+ N GC+HECV + CRC +GF L D ++C + CA + CE +C +
Sbjct: 365 CASSNHGCQHECVNAQTSAL-CRCLKGFMLNPDRKTCRRINYCALNKPGCEHECV-NTEE 422
Query: 66 GYSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQMCVNYVGGFECYCSEGHELEADGIS 124
G+ C CR G+ + + C D C Q C+Q+C+N F C CSEG + D +
Sbjct: 423 GHYCRCRQGYN-LDPNGKTCSRVDHCAQQDHGCEQLCLNTEESFVCQCSEGFLINDDLKT 481
Query: 125 CSPA 128
CS A
Sbjct: 482 CSRA 485
Score = 71.0 bits (171), Expect = 6e-12
Identities = 43/121 (35%), Positives = 55/121 (44%), Gaps = 8/121 (6%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 65
C N GCE+ CV D +C+C EG L +DG++C D CA CE C
Sbjct: 488 CLLSNHGCEYSCVN-TDKSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSC-VSSED 545
Query: 66 GYSCHCRLGFRPAEDDPHRCVDTDECQ-IAGVCQQMCVNYVGGFECYCSEGHELEADGIS 124
+ C C G+ DD C D CQ + C+ +CVN + C C EG L DG
Sbjct: 546 SFVCQCFEGY-ILRDDGKTCRRKDVCQDVNHGCEHLCVNSGESYVCKCLEGFRLAEDGKR 604
Query: 125 C 125
C
Sbjct: 605 C 605
Score = 65.2 bits (156), Expect = 4e-10
Identities = 42/128 (32%), Positives = 58/128 (44%), Gaps = 8/128 (6%)
Query: 4 LCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAP--CEQQC 59
LC CS C H C+ ++ C+C +G+ L+ D ++C +D CA CEQ C
Sbjct: 236 LCTVHMCSVLEHNCAHFCLNTPGSYI-CKCKQGYILSTDQKTCRIQDLCATEDHGCEQLC 294
Query: 60 EPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHEL 118
+ C C G+ AED RC D C C+ CVN + C C EG L
Sbjct: 295 V-NMLGSFVCQCYSGYTLAEDGK-RCTAMDYCASENHGCEHECVNAESSYLCRCHEGFAL 352
Query: 119 EADGISCS 126
+D +CS
Sbjct: 353 NSDKKTCS 360
Score = 45.7 bits (106), Expect = 3e-04
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCE 56
C GCEH CV + ++ CRC+EGF LA DG+ C+ C + P +
Sbjct: 611 CKSTQHGCEHMCVNNGNSYL-CRCSEGFVLAEDGKHCK-RCTEGPID 655
>gb|AAG25939.1|AF276425_1 (AF276425) EGF-related protein SCUBE1 [Mus musculus]
Length = 961
Score = 88.2 bits (215), Expect = 4e-17
Identities = 46/119 (38%), Positives = 63/119 (52%), Gaps = 6/119 (5%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCA--QAPCEQQCEPGGPQGY 67
C+ NGGC+H C E+ D C C + + L ADGR+C + CA C++ C+ G
Sbjct: 206 CNYGNGGCQHSC-EDTDTGPMCGCHQKYALHADGRTCIETCAVNNGGCDRTCKDTAT-GV 263
Query: 68 SCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISC 125
C C +GF + D C D +EC + G C C N VG FEC C +GH+L D +C
Sbjct: 264 RCSCPVGFT-LQPDGKTCKDINECLMNNGGCDHFCRNTVGSFECGCQKGHKLLTDERTC 321
Score = 78.8 bits (191), Expect = 3e-14
Identities = 41/121 (33%), Positives = 58/121 (47%), Gaps = 8/121 (6%)
Query: 2 GPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQ--APCEQ 57
G C+ T C+ +NGGC+ C + G V C C GF L DG++C+D C C+
Sbjct: 238 GRTCIET-CAVNNGGCDRTCKDTATG-VRCSCPVGFTLQPDGKTCKDINECLMNNGGCDH 295
Query: 58 QCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHE 117
C + C C+ G + D+ C D DEC C +C+N G F+C C G+
Sbjct: 296 FCR-NTVGSFECGCQKGHKLLTDE-RTCQDIDECSFERTCDHICINSPGSFQCLCRRGYT 353
Query: 118 L 118
L
Sbjct: 354 L 354
Score = 75.7 bits (183), Expect = 2e-13
Identities = 43/120 (35%), Positives = 58/120 (47%), Gaps = 8/120 (6%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA-QAPCEQQCEPGGPQG 66
C +NGGC+H C V G C C +G +L D R+C+D C+ + C+ C P
Sbjct: 286 CLMNNGGCDHFCRNTV-GSFECGCQKGHKLLTDERTCQDIDECSFERTCDHICI-NSPGS 343
Query: 67 YSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISC 125
+ C CR G+ C D DEC + G C+Q CVN G +EC C G L + C
Sbjct: 344 FQCLCRRGYTLYGTT--HCGDVDECSMNNGSCEQGCVNTRGSYECVCPPGRRLHWNQKDC 401
Score = 70.2 bits (169), Expect = 1e-11
Identities = 44/126 (34%), Positives = 56/126 (43%), Gaps = 16/126 (12%)
Query: 10 CSPDNGGCEHECV-EEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGG----- 63
CS C + + + C C G++ +GR CED CE GG
Sbjct: 37 CSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGRQCEDI---DECENDYYNGGCVHDC 91
Query: 64 ---PQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELE 119
P Y C C GF A D H C+D DECQ G CQQ+CVN +G +EC C G L
Sbjct: 92 INIPGNYRCTCFDGFMLAHDG-HNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLS 150
Query: 120 ADGISC 125
+ +C
Sbjct: 151 DNQHTC 156
Score = 56.2 bits (133), Expect = 2e-07
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 13/125 (10%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQA--------PCEQQCEP 61
C +NGGC+ CV + G C+C GF L+ + +C + C C
Sbjct: 121 CQDNNGGCQQICVNAM-GSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRE 179
Query: 62 GGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEA 120
G +C CR GF A++ C T C G CQ C + G C C + + L A
Sbjct: 180 TPKGGVACDCRPGFDLAQNQKD-CTLT--CNYGNGGCQHSCEDTDTGPMCGCHQKYALHA 236
Query: 121 DGISC 125
DG +C
Sbjct: 237 DGRTC 241
>gb|AAB80944.1| (AF013751) fibulin-1 D [Danio rerio]
Length = 681
Score = 86.6 bits (211), Expect = 1e-16
Identities = 45/115 (39%), Positives = 61/115 (52%), Gaps = 8/115 (6%)
Query: 17 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 74
C H+C E + G C CT GF+LA DGR+C+D C +PC Q C Y +CR G
Sbjct: 386 CAHKC-ENILGSYKCSCTAGFKLADDGRNCDDVNECESSPCSQGC-ANVYGSYQSYCRRG 443
Query: 75 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 125
++ ++ D C D DEC + +C C N G F C C + G+ L A+G SC
Sbjct: 444 YQLSDADGITCEDIDECALPTGGHICSYRCHNTPGSFHCTCPASGYTLAANGRSC 498
Score = 79.2 bits (192), Expect = 2e-14
Identities = 47/120 (39%), Positives = 60/120 (49%), Gaps = 10/120 (8%)
Query: 12 PDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP---CEQQCEPGGPQG 66
PDN H C+ V G C C GF + RSCE D C P C +CE
Sbjct: 339 PDNSCDGHGCINLV-GSYRCECRTGFIFNSISRSCEDIDECRNYPGRLCAHKCE-NILGS 396
Query: 67 YSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHEL-EADGISC 125
Y C C GF+ A DD C D +EC+ + C Q C N G ++ YC G++L +ADGI+C
Sbjct: 397 YKCSCTAGFKLA-DDGRNCDDVNECE-SSPCSQGCANVYGSYQSYCRRGYQLSDADGITC 454
Score = 56.6 bits (134), Expect = 1e-07
Identities = 33/102 (32%), Positives = 45/102 (43%), Gaps = 7/102 (6%)
Query: 30 SCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGG----PQGYSCHCRLGFRPAEDDPHRC 85
S C G+ L A+G C D A + C+ G Y C CR GF C
Sbjct: 314 SVTCGRGYHLNAEGTRCVDIDECAGPDNSCDGHGCINLVGSYRCECRTGFI-FNSISRSC 372
Query: 86 VDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
D DEC+ +C C N +G ++C C+ G +L DG +C
Sbjct: 373 EDIDECRNYPGRLCAHKCENILGSYKCSCTAGFKLADDGRNC 414
Score = 48.0 bits (112), Expect = 5e-05
Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 13/84 (15%)
Query: 42 DGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAG---VCQ 98
D ++ ED C A C Q+C G +C C GF+ D H C D +EC + V
Sbjct: 154 DAQNTEDQCRAAGCAQRCLNG-----TCSCLDGFKLKTDGKH-CEDINECLLGPHHCVTG 207
Query: 99 QMCVNYVGGFECY----CSEGHEL 118
+ C+N +G + C C G+EL
Sbjct: 208 ERCINTLGSYRCQREISCGTGYEL 231
Score = 46.9 bits (109), Expect = 1e-04
Identities = 38/128 (29%), Positives = 50/128 (38%), Gaps = 28/128 (21%)
Query: 16 GCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGP-----QGYS 68
GC C+ +C C +GF+L DG+ CED C P C G Y
Sbjct: 166 GCAQRCLNG-----TCSCLDGFKLKTDGKHCEDINECLLGP--HHCVTGERCINTLGSYR 218
Query: 69 CH----CRLGFRPAEDDPHRCVDTDECQIAG---VCQQMCVNYVGGFEC----YCSEGHE 117
C C G+ D ++C D DEC + + C N G F C C+ G
Sbjct: 219 CQREISCGTGYELT--DNNKCKDIDECDLGTHNCAAEMECQNTAGSFRCRPRMQCAAGFI 276
Query: 118 LEADGISC 125
+A G SC
Sbjct: 277 QDALG-SC 283
Score = 34.0 bits (76), Expect = 0.86
Identities = 29/107 (27%), Positives = 40/107 (37%), Gaps = 12/107 (11%)
Query: 10 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCEDPCAQAPCEQQCE------ 60
C+ GG C + C G C C G+ LAA+GRSC+D C
Sbjct: 460 CALPTGGHICSYRC-HNTPGSFHCTCPASGYTLAANGRSCQDIDECLTGTHSCSESESCF 518
Query: 61 --PGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYV 105
GG + S C +R + D R D + CQ ++ V
Sbjct: 519 NIQGGFRCLSFDCPANYRRSGDTRPRVDRADIIRCVKSCQHNDISCV 565
>gb|AAD41769.1|AF112153_1 (AF112153) developmental arteries and neural crest EGF-like protein
[Rattus norvegicus]
Length = 448
Score = 85.0 bits (207), Expect = 4e-16
Identities = 46/119 (38%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Query: 10 CSPDNGGCEHE--CVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGY 67
C+ D+ C C+ +G +C CT+G+ L D C C+Q C P Y
Sbjct: 131 CATDSHQCNPTQICIN-TEGGYTCSCTDGYWLLEGQCLDIDECRYGYCQQLCA-NVPGSY 188
Query: 68 SCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCS 126
SC C GF DD C D +EC+ C Q CVN G F C C G+ELE DGI CS
Sbjct: 189 SCTCNPGFT-LNDDGRSCQDVNECETENPCVQTCVNTYGSFICRCDPGYELEEDGIHCS 246
Score = 76.5 bits (185), Expect = 1e-13
Identities = 46/115 (40%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PC-AQAPCEQQCEPGGPQGYSCHC 71
G C+ C V G SC C GF L DGRSC+D C + PC Q C + C C
Sbjct: 175 GYCQQLCAN-VPGSYSCTCNPGFTLNDDGRSCQDVNECETENPCVQTCV-NTYGSFICRC 232
Query: 72 RLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYCSEGHELEADGISC 125
G+ ED H C D DEC + +CQ CVN G + C C G+ L D SC
Sbjct: 233 DPGYELEEDGIH-CSDMDECSFSEFLCQHECVNQPGSYFCSCPPGYVLLEDNRSC 286
Score = 42.2 bits (97), Expect = 0.003
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 5/51 (9%)
Query: 71 CRLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFECYCSEGHEL 118
CR G++ D+ ++CVD DEC + C Q+C+N GG+ C C++G+ L
Sbjct: 113 CRFGYQM--DEGNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWL 161
Score = 40.2 bits (92), Expect = 0.011
Identities = 34/129 (26%), Positives = 41/129 (31%), Gaps = 41/129 (31%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSC 69
CS C+HECV + G C C G+ L D RSC+D
Sbjct: 251 CSFSEFLCQHECVNQ-PGSYFCSCPPGYVLLEDNRSCQD--------------------- 288
Query: 70 HCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFEC----YCSEGHELEADGISC 125
E H C Q C N GGF+C C E + L D
Sbjct: 289 -----INECEHRNHTCTPL----------QTCYNLQGGFKCIDPIVCEEPYLLIGDNRCM 333
Query: 126 SPAGAMGAQ 134
PA G +
Sbjct: 334 CPAENTGCR 342
>ref|NP_035942.1| fibulin 5 [Mus musculus]
sp|Q9WVH9|FBL5_MOUSE FIBULIN-5 PRECURSOR (FIBL-5) (DEVELOPMENTAL ARTERIES AND NEURAL
CREST EGF-LIKE PROTEIN) (DANCE)
gb|AAD41767.1|AF112151_1 (AF112151) developmental arteries and neural crest EGF-like protein
[Mus musculus]
Length = 448
Score = 85.0 bits (207), Expect = 4e-16
Identities = 46/119 (38%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Query: 10 CSPDNGGCEHE--CVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGY 67
C+ D+ C C+ +G +C CT+G+ L D C C+Q C P Y
Sbjct: 131 CATDSHQCNPTQICIN-TEGGYTCSCTDGYWLLEGQCLDIDECRYGYCQQLCA-NVPGSY 188
Query: 68 SCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCS 126
SC C GF DD C D +EC+ C Q CVN G F C C G+ELE DGI CS
Sbjct: 189 SCTCNPGFT-LNDDGRSCQDVNECETENPCVQTCVNTYGSFICRCDPGYELEEDGIHCS 246
Score = 76.1 bits (184), Expect = 2e-13
Identities = 46/115 (40%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PC-AQAPCEQQCEPGGPQGYSCHC 71
G C+ C V G SC C GF L DGRSC+D C + PC Q C + C C
Sbjct: 175 GYCQQLCAN-VPGSYSCTCNPGFTLNDDGRSCQDVNECETENPCVQTCV-NTYGSFICRC 232
Query: 72 RLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYCSEGHELEADGISC 125
G+ ED H C D DEC + +CQ CVN G + C C G+ L D SC
Sbjct: 233 DPGYELEEDGIH-CSDMDECSFSEFLCQHECVNQPGSYFCSCPPGYVLLDDNRSC 286
Score = 53.5 bits (126), Expect = 1e-06
Identities = 40/130 (30%), Positives = 52/130 (39%), Gaps = 15/130 (11%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED----PCAQAPCEQQCEPGGPQ 65
C +N C CV G CRC G+ L DG C D ++ C+ +C P
Sbjct: 211 CETENP-CVQTCVNTY-GSFICRCDPGYELEEDGIHCSDMDECSFSEFLCQHECV-NQPG 267
Query: 66 GYSCHCRLGFRPAEDDPHRCVDTDECQIAG---VCQQMCVNYVGGFECY----CSEGHEL 118
Y C C G+ DD C D +EC+ Q C N GGF+C C E + L
Sbjct: 268 SYFCSCPPGY-VLLDDNRSCQDINECEHRNHTCTSLQTCYNLQGGFKCIDPISCEEPYLL 326
Query: 119 EADGISCSPA 128
+ PA
Sbjct: 327 IGENRCMCPA 336
Score = 42.2 bits (97), Expect = 0.003
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 5/51 (9%)
Query: 71 CRLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFECYCSEGHEL 118
CR G++ D+ ++CVD DEC + C Q+C+N GG+ C C++G+ L
Sbjct: 113 CRFGYQM--DEGNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWL 161
>ref|XP_006089.1| CEGP1 protein [Homo sapiens]
Length = 1025
Score = 83.1 bits (202), Expect = 1e-15
Identities = 45/120 (37%), Positives = 63/120 (52%), Gaps = 8/120 (6%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA-QAPCEQQCEPGGPQG 66
C NGGC+H C + + G C C +GF+L D +SC+D C+ C+ C P
Sbjct: 353 CQTRNGGCDHFC-KNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCI-NHPGT 410
Query: 67 YSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISC 125
++C C G+ C DT+EC I G CQQ+CVN VG +EC C G++L + C
Sbjct: 411 FACACNRGYTLYGFT--HCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDC 468
Score = 78.8 bits (191), Expect = 3e-14
Identities = 38/113 (33%), Positives = 56/113 (48%), Gaps = 7/113 (6%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED----PCAQAPCEQQCEPGGPQ 65
C+ +NGGC+ C + G V C C GF L DG++C+D C+ C+
Sbjct: 312 CAVNNGGCDRTCKDTSTG-VHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCK-NIVG 369
Query: 66 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHEL 118
+ C C+ GF+ D+ C D DEC + C C+N+ G F C C+ G+ L
Sbjct: 370 SFDCGCKKGFKLLTDEKS-CQDVDECSLDRTCDHSCINHPGTFACACNRGYTL 421
Score = 64.8 bits (155), Expect = 5e-10
Identities = 39/101 (38%), Positives = 48/101 (46%), Gaps = 10/101 (9%)
Query: 31 CRCTEGFRLAADGRSCED--PCAQ---APCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRC 85
C C G++ +GR CED C C C P Y C C GF A D H C
Sbjct: 97 CSCKPGYQ--GEGRQCEDIDECGNELNGGCVHDCL-NIPGNYRCTCFDGFMLAHDG-HNC 152
Query: 86 VDTDEC-QIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
+D DEC + G CQ CVN +G +EC C EG L + +C
Sbjct: 153 LDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC 193
Score = 63.6 bits (152), Expect = 1e-09
Identities = 40/125 (32%), Positives = 55/125 (44%), Gaps = 13/125 (10%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQA--------PCEQQCEP 61
C +NGGC+H CV V G C C EGF L+ + +C + C C+
Sbjct: 158 CLENNGGCQHTCV-NVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKE 216
Query: 62 GGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEA 120
+C CR GF A++ C+ T C G CQ C + G EC C +++
Sbjct: 217 APRGSVACECRPGFELAKNQ-RDCILT--CNHGNGGCQHSCDDTADGPECSCHPQYKMHT 273
Query: 121 DGISC 125
DG SC
Sbjct: 274 DGRSC 278
Score = 58.6 bits (139), Expect = 4e-08
Identities = 38/122 (31%), Positives = 54/122 (44%), Gaps = 13/122 (10%)
Query: 14 NGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQ--APCEQQCEPGGPQGYSC 69
NGGC H+C+ + G+ C C +GF LA DG +C D C + C+ C Y C
Sbjct: 121 NGGCVHDCLN-IPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTC-VNVMGSYEC 178
Query: 70 HCRLGFRPAEDDPHRCVDTDECQIAGV-----CQQMCVNYV-GGFECYCSEGHELEADGI 123
C+ GF D+ H C+ E ++ + C +C G C C G EL +
Sbjct: 179 CCKEGFF-LSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQR 237
Query: 124 SC 125
C
Sbjct: 238 DC 239
Score = 54.7 bits (129), Expect = 5e-07
Identities = 37/150 (24%), Positives = 53/150 (34%), Gaps = 33/150 (22%)
Query: 7 GTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPC--AQAPCEQQCEPGGP 64
G C + GC H C E G V+C C GF LA + R C C C+ C+
Sbjct: 200 GLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDTA- 258
Query: 65 QGYSCHCRLGFRPAEDDPHRCVDTDE----------------------------CQI-AG 95
G C C ++ D C++ ++ C + G
Sbjct: 259 DGPECSCHPQYK-MHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNG 317
Query: 96 VCQQMCVNYVGGFECYCSEGHELEADGISC 125
C + C + G C C G L+ DG +C
Sbjct: 318 GCDRTCKDTSTGVHCSCPVGFTLQLDGKTC 347
>ref|NP_066025.1| CEGP1 protein [Homo sapiens]
emb|CAB92285.1| (AJ400877) CEGP1 protein [Homo sapiens]
Length = 999
Score = 83.1 bits (202), Expect = 1e-15
Identities = 45/120 (37%), Positives = 63/120 (52%), Gaps = 8/120 (6%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA-QAPCEQQCEPGGPQG 66
C NGGC+H C + + G C C +GF+L D +SC+D C+ C+ C P
Sbjct: 327 CQTRNGGCDHFC-KNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCI-NHPGT 384
Query: 67 YSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISC 125
++C C G+ C DT+EC I G CQQ+CVN VG +EC C G++L + C
Sbjct: 385 FACACNRGYTLYGFT--HCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDC 442
Score = 78.8 bits (191), Expect = 3e-14
Identities = 38/113 (33%), Positives = 56/113 (48%), Gaps = 7/113 (6%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED----PCAQAPCEQQCEPGGPQ 65
C+ +NGGC+ C + G V C C GF L DG++C+D C+ C+
Sbjct: 286 CAVNNGGCDRTCKDTSTG-VHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCK-NIVG 343
Query: 66 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHEL 118
+ C C+ GF+ D+ C D DEC + C C+N+ G F C C+ G+ L
Sbjct: 344 SFDCGCKKGFKLLTDEKS-CQDVDECSLDRTCDHSCINHPGTFACACNRGYTL 395
Score = 64.8 bits (155), Expect = 5e-10
Identities = 39/101 (38%), Positives = 48/101 (46%), Gaps = 10/101 (9%)
Query: 31 CRCTEGFRLAADGRSCED--PCAQ---APCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRC 85
C C G++ +GR CED C C C P Y C C GF A D H C
Sbjct: 71 CSCKPGYQ--GEGRQCEDIDECGNELNGGCVHDCL-NIPGNYRCTCFDGFMLAHDG-HNC 126
Query: 86 VDTDEC-QIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 125
+D DEC + G CQ CVN +G +EC C EG L + +C
Sbjct: 127 LDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC 167
Score = 63.6 bits (152), Expect = 1e-09
Identities = 40/125 (32%), Positives = 55/125 (44%), Gaps = 13/125 (10%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQA--------PCEQQCEP 61
C +NGGC+H CV V G C C EGF L+ + +C + C C+
Sbjct: 132 CLENNGGCQHTCV-NVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKE 190
Query: 62 GGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEA 120
+C CR GF A++ C+ T C G CQ C + G EC C +++
Sbjct: 191 APRGSVACECRPGFELAKNQ-RDCILT--CNHGNGGCQHSCDDTADGPECSCHPQYKMHT 247
Query: 121 DGISC 125
DG SC
Sbjct: 248 DGRSC 252
Score = 58.6 bits (139), Expect = 4e-08
Identities = 38/122 (31%), Positives = 54/122 (44%), Gaps = 13/122 (10%)
Query: 14 NGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQ--APCEQQCEPGGPQGYSC 69
NGGC H+C+ + G+ C C +GF LA DG +C D C + C+ C Y C
Sbjct: 95 NGGCVHDCLN-IPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTC-VNVMGSYEC 152
Query: 70 HCRLGFRPAEDDPHRCVDTDECQIAGV-----CQQMCVNYV-GGFECYCSEGHELEADGI 123
C+ GF D+ H C+ E ++ + C +C G C C G EL +
Sbjct: 153 CCKEGFF-LSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQR 211
Query: 124 SC 125
C
Sbjct: 212 DC 213
Score = 54.7 bits (129), Expect = 5e-07
Identities = 37/150 (24%), Positives = 53/150 (34%), Gaps = 33/150 (22%)
Query: 7 GTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPC--AQAPCEQQCEPGGP 64
G C + GC H C E G V+C C GF LA + R C C C+ C+
Sbjct: 174 GLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDTA- 232
Query: 65 QGYSCHCRLGFRPAEDDPHRCVDTDE----------------------------CQI-AG 95
G C C ++ D C++ ++ C + G
Sbjct: 233 DGPECSCHPQYK-MHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNG 291
Query: 96 VCQQMCVNYVGGFECYCSEGHELEADGISC 125
C + C + G C C G L+ DG +C
Sbjct: 292 GCDRTCKDTSTGVHCSCPVGFTLQLDGKTC 321
>ref|NP_002371.1| matrilin 2; Human matrilin-2 precursor mRNA, partial cds [Homo
sapiens]
gb|AAC51260.2| (U69263) matrilin-2 precursor [Homo sapiens]
Length = 956
Score = 82.3 bits (200), Expect = 2e-15
Identities = 48/121 (39%), Positives = 61/121 (49%), Gaps = 8/121 (6%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAP--CEQQCEPGGPQ 65
C+ + GCEH CV D V C+C EG+ L DG++C +D C CE C
Sbjct: 529 CALGDHGCEHSCVSSEDSFV-CQCFEGYILREDGKTCRRKDVCQAIDHGCEHICV-NSDD 586
Query: 66 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHELEADGIS 124
Y+C C +GFR AED RC D C+ C+ +CVN + C CSEG L DG
Sbjct: 587 SYTCECLVGFRLAEDGK-RCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRR 645
Query: 125 C 125
C
Sbjct: 646 C 646
Score = 79.6 bits (193), Expect = 2e-14
Identities = 45/122 (36%), Positives = 61/122 (49%), Gaps = 8/122 (6%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 65
C+ + GCEHECV + + CRC G+ L +G++C D CAQ CEQ C
Sbjct: 406 CALNKPGCEHECVNMEESYY-CRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCL-NTED 463
Query: 66 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHELEADGIS 124
+ C C GF +D C D C ++ C+ CVN F C C EGH L +DG +
Sbjct: 464 SFVCQCSEGFL-INEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKT 522
Query: 125 CS 126
C+
Sbjct: 523 CA 524
Score = 74.5 bits (180), Expect = 6e-13
Identities = 46/128 (35%), Positives = 59/128 (45%), Gaps = 8/128 (6%)
Query: 4 LCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAP--CEQQC 59
LC CS C H C+ + G CRC +G+ L +D +C +D CA CEQ C
Sbjct: 236 LCTAHMCSTLEHNCAHFCIN-IPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLC 294
Query: 60 EPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHEL 118
P + C C G+ AED RCV D C C+ CVN G + C C EG L
Sbjct: 295 V-NVPGSFVCQCYSGYALAEDGK-RCVAVDYCASENHGCEHECVNADGSYLCQCHEGFAL 352
Query: 119 EADGISCS 126
D +C+
Sbjct: 353 NPDKKTCT 360
Score = 67.1 bits (161), Expect = 9e-11
Identities = 41/121 (33%), Positives = 53/121 (42%), Gaps = 8/121 (6%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 65
C+ ++ CE CV V G C+C G+ LA DG+ C D CA CE +C
Sbjct: 283 CAMEDHNCEQLCVN-VPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECV-NADG 340
Query: 66 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHELEADGIS 124
Y C C GF D C D C + CQ CVN + C+C +G L D +
Sbjct: 341 SYLCQCHEGFA-LNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKT 399
Query: 125 C 125
C
Sbjct: 400 C 400
Score = 66.3 bits (159), Expect = 2e-10
Identities = 42/121 (34%), Positives = 55/121 (44%), Gaps = 8/121 (6%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 65
C + GCE+ CV +D +C+C EG L +DG++C D CA CE C
Sbjct: 488 CLLSDHGCEYSCVN-MDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSC-VSSED 545
Query: 66 GYSCHCRLGFRPAEDDPHRCVDTDECQ-IAGVCQQMCVNYVGGFECYCSEGHELEADGIS 124
+ C C G+ ED C D CQ I C+ +CVN + C C G L DG
Sbjct: 546 SFVCQCFEGYILREDG-KTCRRKDVCQAIDHGCEHICVNSDDSYTCECLVGFRLAEDGKR 604
Query: 125 C 125
C
Sbjct: 605 C 605
Score = 46.9 bits (109), Expect = 1e-04
Identities = 20/47 (42%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCE 56
C + GCEH CV + ++ C+C+EGF LA DGR C+ C + P +
Sbjct: 611 CKSTHHGCEHICVNNGNSYI-CKCSEGFVLAEDGRRCK-KCTEGPID 655
>ref|NP_062026.1| fibulin 5 [Rattus norvegicus]
gb|AAD25101.1|AF137350_1 (AF137350) embryonic vascular EGF repeat-containing protein EVEC
[Rattus norvegicus]
Length = 448
Score = 82.3 bits (200), Expect = 2e-15
Identities = 45/119 (37%), Positives = 56/119 (46%), Gaps = 5/119 (4%)
Query: 10 CSPDNGGCEHE--CVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGY 67
C+ D+ C C+ +G +C CT+G+ L D C C+Q C P Y
Sbjct: 131 CATDSHQCNPTQICIN-TEGGYTCSCTDGYWLLEGQCLDIDECRYGYCQQLCA-NVPGSY 188
Query: 68 SCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCS 126
SC C GF DD C D +EC+ C Q CVN G F C C G+E E DGI CS
Sbjct: 189 SCTCNPGFT-LNDDGRSCQDVNECETENPCVQTCVNTYGSFICRCDPGYEPEEDGIHCS 246
Score = 80.4 bits (195), Expect = 1e-14
Identities = 47/115 (40%), Positives = 56/115 (47%), Gaps = 7/115 (6%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PC-AQAPCEQQCEPGGPQGYSCHC 71
G C+ C V G SC C GF L DGRSC+D C + PC Q C + C C
Sbjct: 175 GYCQQLCAN-VPGSYSCTCNPGFTLNDDGRSCQDVNECETENPCVQTCV-NTYGSFICRC 232
Query: 72 RLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYCSEGHELEADGISC 125
G+ P ED H C D DEC + +CQ CVN G + C C G+ L D SC
Sbjct: 233 DPGYEPEEDGIH-CSDMDECSFSEFLCQHECVNQPGSYFCSCPPGYVLLEDNRSC 286
Score = 42.2 bits (97), Expect = 0.003
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 5/51 (9%)
Query: 71 CRLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFECYCSEGHEL 118
CR G++ D+ ++CVD DEC + C Q+C+N GG+ C C++G+ L
Sbjct: 113 CRFGYQM--DEGNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWL 161
Score = 40.2 bits (92), Expect = 0.011
Identities = 34/129 (26%), Positives = 41/129 (31%), Gaps = 41/129 (31%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSC 69
CS C+HECV + G C C G+ L D RSC+D
Sbjct: 251 CSFSEFLCQHECVNQ-PGSYFCSCPPGYVLLEDNRSCQD--------------------- 288
Query: 70 HCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFEC----YCSEGHELEADGISC 125
E H C Q C N GGF+C C E + L D
Sbjct: 289 -----INECEHRNHTCTPL----------QTCYNLQGGFKCIDPIVCEEPYLLIGDNRCM 333
Query: 126 SPAGAMGAQ 134
PA G +
Sbjct: 334 CPAENTGCR 342
>ref|XP_007402.1| fibulin 5 [Homo sapiens]
Length = 504
Score = 81.9 bits (199), Expect = 3e-15
Identities = 45/119 (37%), Positives = 56/119 (46%), Gaps = 5/119 (4%)
Query: 10 CSPDNGGCEHE--CVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGY 67
C+ D+ C C+ +G +C CT+G+ L D C C+Q C P Y
Sbjct: 187 CATDSHQCNPTQICIN-TEGGYTCSCTDGYWLLEGQCLDIDECRYGYCQQLCA-NVPGSY 244
Query: 68 SCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCS 126
SC C GF ED C D +EC C Q CVN G F C C G+ELE DG+ CS
Sbjct: 245 SCTCNPGFTLNEDG-RSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCS 302
Score = 77.3 bits (187), Expect = 8e-14
Identities = 47/115 (40%), Positives = 56/115 (47%), Gaps = 7/115 (6%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA-QAPCEQQCEPGGPQGYSCHC 71
G C+ C V G SC C GF L DGRSC+D CA + PC Q C + C C
Sbjct: 231 GYCQQLCAN-VPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCV-NTYGSFICRC 288
Query: 72 RLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYCSEGHELEADGISC 125
G+ ED H C D DEC + +CQ CVN G + C C G+ L D SC
Sbjct: 289 DPGYELEEDGVH-CSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSC 342
Score = 42.6 bits (98), Expect = 0.002
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 5/51 (9%)
Query: 71 CRLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFECYCSEGHEL 118
CR G++ D+ ++CVD DEC + C Q+C+N GG+ C C++G+ L
Sbjct: 169 CRFGYQM--DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWL 217
Score = 39.1 bits (89), Expect = 0.026
Identities = 34/129 (26%), Positives = 47/129 (36%), Gaps = 41/129 (31%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSC 69
CS C+HECV + G C C G+ L D RSC+D +CE + ++C
Sbjct: 307 CSFSEFLCQHECVNQ-PGTYFCSCPPGYILLDDNRSCQD-------INECE---HRNHTC 355
Query: 70 HCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECY----CSEGHELEADGISC 125
+ QQ C N GGF+C C E + +D
Sbjct: 356 N--------------------------LQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCM 389
Query: 126 SPAGAMGAQ 134
PA G +
Sbjct: 390 CPAENPGCR 398
Score = 30.9 bits (68), Expect = 7.5
Identities = 20/55 (36%), Positives = 26/55 (46%), Gaps = 5/55 (9%)
Query: 59 CEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQ-IAGVCQ--QMCVNYVGGFEC 110
C P P C GF + +C+D DEC+ I C+ MCVN GG+ C
Sbjct: 72 CLPS-PGNAQAQCTNGF-DLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 124
>emb|CAB38568.1| (AJ133490) fibulin-5 [Homo sapiens]
gb|AAD41768.1|AF112152_1 (AF112152) developmental arteries and neural crest EGF-like protein
[Homo sapiens]
Length = 448
Score = 81.9 bits (199), Expect = 3e-15
Identities = 45/119 (37%), Positives = 56/119 (46%), Gaps = 5/119 (4%)
Query: 10 CSPDNGGCEHE--CVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGY 67
C+ D+ C C+ +G +C CT+G+ L D C C+Q C P Y
Sbjct: 131 CATDSHQCNPTQICIN-TEGGYTCSCTDGYWLLEGQCLDIDECRYGYCQQLCA-NVPGSY 188
Query: 68 SCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCS 126
SC C GF ED C D +EC C Q CVN G F C C G+ELE DG+ CS
Sbjct: 189 SCTCNPGFTLNEDG-RSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCS 246
Score = 77.3 bits (187), Expect = 8e-14
Identities = 47/115 (40%), Positives = 56/115 (47%), Gaps = 7/115 (6%)
Query: 15 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA-QAPCEQQCEPGGPQGYSCHC 71
G C+ C V G SC C GF L DGRSC+D CA + PC Q C + C C
Sbjct: 175 GYCQQLCAN-VPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCV-NTYGSFICRC 232
Query: 72 RLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYCSEGHELEADGISC 125
G+ ED H C D DEC + +CQ CVN G + C C G+ L D SC
Sbjct: 233 DPGYELEEDGVH-CSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSC 286
Score = 42.6 bits (98), Expect = 0.002
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 5/51 (9%)
Query: 71 CRLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFECYCSEGHEL 118
CR G++ D+ ++CVD DEC + C Q+C+N GG+ C C++G+ L
Sbjct: 113 CRFGYQM--DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWL 161
Score = 39.1 bits (89), Expect = 0.026
Identities = 34/129 (26%), Positives = 47/129 (36%), Gaps = 41/129 (31%)
Query: 10 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSC 69
CS C+HECV + G C C G+ L D RSC+D +CE + ++C
Sbjct: 251 CSFSEFLCQHECVNQ-PGTYFCSCPPGYILLDDNRSCQD-------INECE---HRNHTC 299
Query: 70 HCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECY----CSEGHELEADGISC 125
+ QQ C N GGF+C C E + +D
Sbjct: 300 N--------------------------LQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCM 333
Query: 126 SPAGAMGAQ 134
PA G +
Sbjct: 334 CPAENPGCR 342
Score = 30.9 bits (68), Expect = 7.5
Identities = 20/55 (36%), Positives = 26/55 (46%), Gaps = 5/55 (9%)
Query: 59 CEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQ-IAGVCQ--QMCVNYVGGFEC 110
C P P C GF + +C+D DEC+ I C+ MCVN GG+ C
Sbjct: 16 CLPS-PGNAQAQCTNGF-DLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 68
Database: nr
Number of letters in database: 188,543,631
Number of sequences in database: 596,480
Lambda K H
0.321 0.140 0.492
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64503317
Number of Sequences: 596480
Number of extensions: 2957512
Number of successful extensions: 13207
Number of sequences better than 10.0: 1028
Number of HSP's better than 10.0 without gapping: 427
Number of HSP's successfully gapped in prelim test: 605
Number of HSP's that attempted gapping in prelim test: 5947
Number of HSP's gapped (non-prelim): 4552
length of query: 135
length of database: 188,543,631
effective HSP length: 43
effective length of query: 92
effective length of database: 162,894,991
effective search space: 14986339172
effective search space used: 14986339172
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 67 (30.5 bits)