Legend:
Sequences with E-value BETTER than threshold 235 3e-61
208 3e-53
202 2e-51
200 9e-51
197 5e-50
197 5e-50
197 7e-50
197 8e-50
196 1e-49
191 4e-48
182 2e-45
181 4e-45
162 2e-39
158 2e-38
158 3e-38
151 4e-36
143 1e-33
143 1e-33
133 1e-30
133 1e-30
128 4e-29
109 3e-23
107 1e-22
76 3e-13
73 2e-12
71 6e-12
70 1e-11
69 3e-11
69 4e-11
69 4e-11
69 4e-11
69 5e-11
69 5e-11
69 5e-11
67 8e-11
67 1e-10
67 1e-10
67 2e-10
66 2e-10
66 2e-10
65 3e-10
65 4e-10
65 5e-10
64 1e-09
63 1e-09
63 1e-09
62 3e-09
62 4e-09
60 1e-08
60 1e-08
Alignments
>ref|NP_065137.1| tumor endothelial marker 1 precursor [Homo sapiens]
gb|AAG00867.1|AF279142_1 (AF279142) tumor endothelial marker 1 precursor [Homo sapiens]
Length = 757
Score = 235 bits (594), Expect = 3e-61
Identities = 157/157 (100%), Positives = 157/157 (100%)
Query: 1 DPWAAEPRAACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGP 60
DPWAAEPRAACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGP
Sbjct: 19 DPWAAEPRAACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGP 78
Query: 61 ASRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASG 120
ASRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASG
Sbjct: 79 ASRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASG 138
Query: 121 EHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAG 157
EHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAG
Sbjct: 139 EHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAG 175
>gb|AAB80760.1| (AF022743) thrombomodulin [Rattus norvegicus]
Length = 577
Score = 208 bits (525), Expect = 3e-53
Identities = 52/151 (34%), Positives = 68/151 (44%), Gaps = 8/151 (5%)
Query: 9 AACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIG 68
+ C + C+ALF TFL+A +AC+ L G L T R+ A + LV WIG
Sbjct: 28 SQCVGNECFALFQDPVTFLDASQACQRLQGHLMTVRSSVAADVISLLVSDSSMDSRPWIG 87
Query: 69 LQ--RQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGP------CPAQRCVALEASG 120
LQ + PLRGF W TGD T+++ WA+P P C A G
Sbjct: 88 LQLPQGCGDPVHLGPLRGFQWVTGDNHTSYSRWARPNDQSPPLCGPLCVTVSTATEAAPG 147
Query: 121 EHRWLEGSCTLAVDGYLCQFGFEGACPALQD 151
E W E C G+LC+F F C L+
Sbjct: 148 EPAWEEKPCENETKGFLCEFYFAAFCRPLRV 178
>ref|NP_033404.1| thrombomodulin [Mus musculus]
sp|P15306|TRBM_MOUSE THROMBOMODULIN PRECURSOR (FETOMODULIN) (TM)
pir||A60501 thrombomodulin precursor - mouse
emb|CAA32597.1| (X14432) thrombomodulin [Mus musculus]
Length = 577
Score = 202 bits (510), Expect = 2e-51
Identities = 52/151 (34%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
Query: 9 AACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIG 68
+ C C+ALF TFL+A +AC+ L G L T R+ A + L+ WIG
Sbjct: 28 SQCVEHECFALFQGPATFLDASQACQRLQGHLMTVRSSVAADVISLLLSQSSMDLGPWIG 87
Query: 69 LQ--RQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASG-GPCPAQRCVALE-----ASG 120
LQ + PLRGF W TGD T+++ WA+P P CV + A G
Sbjct: 88 LQLPQGCDDPVHLGPLRGFQWVTGDNHTSYSRWARPNDQTAPLCGPLCVTVSTATEAAPG 147
Query: 121 EHRWLEGSCTLAVDGYLCQFGFEGACPALQD 151
E W E C G+LC+F F +C L
Sbjct: 148 EPAWEEKPCETETQGFLCEFYFTASCRPLTV 178
>ref|NP_034870.1| lymphocyte antigen 68 [Mus musculus]
gb|AAC62649.1| (AF081789) cell surface antigen AA4 [Mus musculus]
gb|AAC63274.1| (AF074856) C1q/MBL/SPA receptor C1qRp [Mus musculus]
gb|AAD47906.1| (AF099939) C1q/MBL/SP-A phagocytic receptor C1qRp [Mus musculus]
Length = 644
Score = 200 bits (504), Expect = 9e-51
Identities = 58/176 (32%), Positives = 86/176 (47%), Gaps = 28/176 (15%)
Query: 2 PW---AAEPRA-ACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVG 57
PW AA+ +A C ++CY + + EA C E GG+LAT ++ EEA+ V +
Sbjct: 17 PWAGAAADSQAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQQALT 76
Query: 58 AGPASRL--------LWIGLQRQARQCQLQR-PLRGFTWTTGDQDTAFTNWAQPASGGPC 108
++ WIGLQR+ C P+RGF+W G +DTA++NW + AS C
Sbjct: 77 QLLKTKAPLEAKMGKFWIGLQREKGNCTYHDLPMRGFSWVGGGEDTAYSNWYK-ASKSSC 135
Query: 109 PAQRCVAL--------EASGEHRWLEGSCTLA------VDGYLCQFGFEGACPALQ 150
+RCV+L S +W E C ++G+LC+F F+G C L
Sbjct: 136 IFKRCVSLILDLSLTPHPSHLPKWHESPCGTPEAPGNSIEGFLCKFNFKGMCRPLA 191
>gb|AAF80402.1|AF160978_1 (AF160978) C1qRp [Rattus norvegicus]
Length = 643
Score = 197 bits (498), Expect = 5e-50
Identities = 56/178 (31%), Positives = 86/178 (47%), Gaps = 26/178 (14%)
Query: 3 WAAEPRA-ACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPA 61
AA+ A C ++CY + + EA C E GG+LAT ++ EEA+ V +
Sbjct: 21 AAADSEAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQEALAQLLK 80
Query: 62 SRL--------LWIGLQRQARQCQLQR-PLRGFTWTTGDQDTAFTNWAQPASGGPCPAQR 112
++ WIGLQR+ +C P++GF+W G +DT ++NW + AS C ++R
Sbjct: 81 TKAPSETKIGKFWIGLQREKGKCTYHDLPMKGFSWVGGGEDTTYSNWYK-ASKSSCISKR 139
Query: 113 CVAL--------EASGEHRWLEGSCTLA------VDGYLCQFGFEGACPALQD-EAGQ 155
CV+L S +W E C ++G+LC+F F+G C L GQ
Sbjct: 140 CVSLILDLSLKPHPSHLPKWHESPCGTPDAPGNSIEGFLCKFNFKGMCSPLALGGPGQ 197
>gb|AAG01572.1|AF136537_1 (AF136537) C1q/MBL/SPA receptor C1qRp precursor [Rattus norvegicus]
Length = 643
Score = 197 bits (498), Expect = 5e-50
Identities = 56/178 (31%), Positives = 86/178 (47%), Gaps = 26/178 (14%)
Query: 3 WAAEPRA-ACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPA 61
AA+ A C ++CY + + EA C E GG+LAT ++ EEA+ V +
Sbjct: 21 AAADSEAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQEALAQLLK 80
Query: 62 SRL--------LWIGLQRQARQCQLQR-PLRGFTWTTGDQDTAFTNWAQPASGGPCPAQR 112
++ WIGLQR+ +C P++GF+W G +DT ++NW + AS C ++R
Sbjct: 81 TKAPSETKIGKFWIGLQREKGKCTYHDLPMKGFSWVGGGEDTTYSNWYK-ASKSSCISKR 139
Query: 113 CVAL--------EASGEHRWLEGSCTLA------VDGYLCQFGFEGACPALQD-EAGQ 155
CV+L S +W E C ++G+LC+F F+G C L GQ
Sbjct: 140 CVSLILDLSLKPHPSHLPKWHESPCGTPDAPGNSIEGFLCKFNFKGMCSPLALGGPGQ 197
>pir||THHUB thrombomodulin precursor [validated] - human
dbj|BAA00149.1| (D00210) thrombomodulin precursor [Homo sapiens]
emb|CAA29045.1| (X05495) thrombomodulin [Homo sapiens]
prf||1403353A thrombomodulin [Homo sapiens]
Length = 575
Score = 197 bits (497), Expect = 7e-50
Identities = 62/166 (37%), Positives = 82/166 (49%), Gaps = 13/166 (7%)
Query: 2 PWAAEPR---AACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVG- 57
P AEP+ + C C+AL+P TFL A + C L G L T R+ A + L+
Sbjct: 18 PAPAEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHLMTVRSSVAADVISLLLNG 77
Query: 58 -AGPASRLLWIGLQRQARQCQLQR--PLRGFTWTTGDQDTAFTNWAQ-PASGGPCPAQRC 113
G R LWIGLQ +R PLRGF W TGD +T+++ WA+ +G P C
Sbjct: 78 DGGVGRRRLWIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSYSRWARLDLNGAPLCGPLC 137
Query: 114 VALEAS-----GEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAG 154
VA+ A+ E W E C + DG+LC+F F C L E G
Sbjct: 138 VAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAVEPG 183
>ref|NP_000352.1| thrombomodulin [Homo sapiens]
sp|P07204|TRBM_HUMAN THROMBOMODULIN PRECURSOR (FETOMODULIN) (TM) (CD141 ANTIGEN)
gb|AAB59508.1| (M16552) thrombomodulin [Homo sapiens]
gb|AAA61175.1| (J02973) thrombomodulin precursor [Homo sapiens]
emb|CAB51954.1| (AL049651) dJ753D10.2 (thrombomodulin) [Homo sapiens]
gb|AAD49735.1|AF169484_1 (AF169484) thrombomodulin precursor [Saimiri sciureus]
Length = 575
Score = 197 bits (496), Expect = 8e-50
Identities = 62/166 (37%), Positives = 82/166 (49%), Gaps = 13/166 (7%)
Query: 2 PWAAEPR---AACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVG- 57
P AEP+ + C C+AL+P TFL A + C L G L T R+ A + L+
Sbjct: 18 PAPAEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHLMTVRSSVAADVISLLLNG 77
Query: 58 -AGPASRLLWIGLQRQARQCQLQR--PLRGFTWTTGDQDTAFTNWAQ-PASGGPCPAQRC 113
G R LWIGLQ +R PLRGF W TGD +T+++ WA+ +G P C
Sbjct: 78 DGGVGRRRLWIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSYSRWARLDLNGAPLCGPLC 137
Query: 114 VALEAS-----GEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAG 154
VA+ A+ E W E C + DG+LC+F F C L E G
Sbjct: 138 VAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAVEPG 183
>ref|XP_009595.1| thrombomodulin [Homo sapiens]
Length = 631
Score = 196 bits (495), Expect = 1e-49
Identities = 62/166 (37%), Positives = 82/166 (49%), Gaps = 13/166 (7%)
Query: 2 PWAAEPR---AACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVG- 57
P AEP+ + C C+AL+P TFL A + C L G L T R+ A + L+
Sbjct: 74 PAPAEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHLMTVRSSVAADVISLLLNG 133
Query: 58 -AGPASRLLWIGLQRQARQCQLQR--PLRGFTWTTGDQDTAFTNWAQ-PASGGPCPAQRC 113
G R LWIGLQ +R PLRGF W TGD +T+++ WA+ +G P C
Sbjct: 134 DGGVGRRRLWIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSYSRWARLDLNGAPLCGPLC 193
Query: 114 VALEAS-----GEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAG 154
VA+ A+ E W E C + DG+LC+F F C L E G
Sbjct: 194 VAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAVEPG 239
>gb|AAB27209.1| thrombomodulin [human, urine, Peptide, 468 aa]
Length = 468
Score = 191 bits (482), Expect = 4e-48
Identities = 61/165 (36%), Positives = 81/165 (48%), Gaps = 13/165 (7%)
Query: 3 WAAEPR---AACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVG-- 57
AEP+ + C C+AL+P TFL A + C L G L T R+ A + L+
Sbjct: 1 APAEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHLMTVRSSVAADVISLLLNGD 60
Query: 58 AGPASRLLWIGLQRQARQCQLQR--PLRGFTWTTGDQDTAFTNWAQ-PASGGPCPAQRCV 114
G R LWIGLQ +R PLRGF W TGD +T+++ WA+ +G P CV
Sbjct: 61 GGVGRRRLWIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSYSRWARLDLNGAPLCGPLCV 120
Query: 115 ALEAS-----GEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAG 154
A+ A+ E W E C + DG+LC+F F C L E G
Sbjct: 121 AVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAVEPG 165
>ref|XP_009596.1| complement component C1q receptor [Homo sapiens]
emb|CAC00597.1| (AL118508) dJ737E23.1 (EGF-like domains containing C1q/MBL/SPA
receptor (C1QR)) [Homo sapiens]
Length = 652
Score = 182 bits (458), Expect = 2e-45
Identities = 52/171 (30%), Positives = 80/171 (46%), Gaps = 25/171 (14%)
Query: 4 AAEPRA-ACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPAS 62
A+ A C ++CY + + EA C + GG+LAT ++ EEAQ V ++
Sbjct: 23 GADTEAVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNLATVKSKEEAQHVQRVLAQLLRR 82
Query: 63 RL--------LWIGLQRQARQC-QLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRC 113
WIGLQR+ +C PL+GF+W G +DT ++NW + C ++RC
Sbjct: 83 EAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGGEDTPYSNWHKELRNS-CISKRC 141
Query: 114 V--------ALEASGEHRWLEGSCTLA------VDGYLCQFGFEGACPALQ 150
V L S +W EG C ++G++C+F F+G C L
Sbjct: 142 VSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVCKFSFKGMCRPLA 192
>ref|NP_036204.1| complement component C1q receptor [Homo sapiens]
gb|AAB53110.1| (U94333) C1qR(p) [Homo sapiens]
Length = 652
Score = 181 bits (456), Expect = 4e-45
Identities = 51/171 (29%), Positives = 80/171 (45%), Gaps = 25/171 (14%)
Query: 4 AAEPRA-ACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPAS 62
A+ A C ++CY + + EA C + GG+LAT ++ EEAQ V ++
Sbjct: 23 GADTEAVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNLATVKSKEEAQHVQRVLAQLLRR 82
Query: 63 RL--------LWIGLQRQARQC-QLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRC 113
WIGLQR+ +C PL+GF+W G +DT ++NW + C ++RC
Sbjct: 83 EAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGGEDTPYSNWHKELRNS-CISKRC 141
Query: 114 VALEAS--------GEHRWLEGSCTLA------VDGYLCQFGFEGACPALQ 150
V+L +W EG C ++G++C+F F+G C L
Sbjct: 142 VSLLLDLSQPLLPNRLPKWSEGPCGSPGSPGSNIEGFVCKFSFKGMCRPLA 192
>gb|AAB80923.1| (AF022742) thrombomodulin precursor [Rattus norvegicus]
Length = 136
Score = 162 bits (408), Expect = 2e-39
Identities = 40/109 (36%), Positives = 53/109 (47%), Gaps = 3/109 (2%)
Query: 9 AACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIG 68
+ C + C+ALF TFL+A +AC+ L G L T R+ A + LV WIG
Sbjct: 28 SQCVGNECFALFQDPVTFLDASQACQRLQGHLMTVRSSVAADVISLLVSDSSMDSRPWIG 87
Query: 69 LQ--RQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGG-PCPAQRCV 114
LQ + PLRGF W TGD T+++ WA+P P CV
Sbjct: 88 LQLPQGCGDPVHLGPLRGFQWVTGDNHTSYSRWARPNDQSPPLCGPLCV 136
>ref|NP_002429.1| mannose receptor, C type 1 [Homo sapiens]
sp|P22897|MANR_HUMAN MACROPHAGE MANNOSE RECEPTOR PRECURSOR
pir||A36563 mannose receptor precursor - human
gb|AAA60389.1| (M93221) mannose receptor [Homo sapiens]
gb|AAA59868.1| (J05550) mannose receptor precursor [Homo sapiens]
Length = 1456
Score = 158 bits (398), Expect = 2e-38
Identities = 41/144 (28%), Positives = 66/144 (45%), Gaps = 18/144 (12%)
Query: 1 DPWAAEPRAACGPSSCYALFPR----RRTFLEAWRACRELGGDLATPRTPEEAQRVDSLV 56
+ W A R S C+ L+ + ++T+ E+ CR LGGDLA+ EE Q + L+
Sbjct: 648 EDWGASSRT----SLCFKLYAKGKHEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLI 703
Query: 57 GA-GPASRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVA 115
A G +L W+GL + P GFTW+ G ++ NWA + C
Sbjct: 704 TASGSYHKLFWLGLTYGS-------PSEGFTWSDGSP-VSYENWAYGEPNNYQNVEYCGE 755
Query: 116 LEASGEHRWLEGSCTLAVDGYLCQ 139
L+ W + +C ++ ++CQ
Sbjct: 756 LKGDPTMSWNDINCE-HLNNWICQ 778
Score = 58.8 bits (141), Expect = 3e-08
Identities = 25/117 (21%), Positives = 44/117 (37%), Gaps = 11/117 (9%)
Query: 23 RRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQCQLQRPL 82
+ T A C+ GDL + ++ E + + V A +IGL L
Sbjct: 818 KETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGL--------LISLD 869
Query: 83 RGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVDGYLCQ 139
+ F W G + + +WA + CV + S W + +C + ++CQ
Sbjct: 870 KKFAWMDGSK-VDYVSWATGEPNFANEDENCVTMY-SNSGFWNDINCGYP-NAFICQ 923
Score = 54.1 bits (129), Expect = 9e-07
Identities = 32/138 (23%), Positives = 55/138 (39%), Gaps = 23/138 (16%)
Query: 14 SSCYALF----PRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGL 69
+ C+ +F R+ + EA +AC GG+L + + +E + + S W GL
Sbjct: 954 NKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSA--WTGL 1011
Query: 70 QRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQR-----CVALEASGE--- 121
+ F WT G + +TNW + GG + CV +
Sbjct: 1012 NDVNSEHT-------FLWTDG-RGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEA 1063
Query: 122 HRWLEGSCTLAVDGYLCQ 139
+W++ +C GY+CQ
Sbjct: 1064 GKWMDDTCDSK-RGYICQ 1080
Score = 52.9 bits (126), Expect = 2e-06
Identities = 35/126 (27%), Positives = 53/126 (41%), Gaps = 13/126 (10%)
Query: 16 CYALFPR-RRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQAR 74
CY + ++ +A CR+ GGDL + T EE + S +G P L WIGL
Sbjct: 373 CYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDEL-WIGLNDIKI 431
Query: 75 QCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCP-AQRCVALEASGEHRWLEGSCTLAV 133
Q F W+ G T FT W + + CV ++ + W + C +
Sbjct: 432 QMY-------FEWSDGTPVT-FTKWLRGEPSHENNRQEDCVVMKGK-DGYWADRGCEWPL 482
Query: 134 DGYLCQ 139
GY+C+
Sbjct: 483 -GYICK 487
Score = 51.0 bits (121), Expect = 8e-06
Identities = 26/116 (22%), Positives = 46/116 (39%), Gaps = 12/116 (10%)
Query: 24 RTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQCQLQRPLR 83
T+ +A ++C++ +L + E + L + LWIGL +
Sbjct: 238 LTWHQARKSCQQQNAELLSITEIHEQTYLTGL--TSSLTSGLWIGLNSLSFN-------S 288
Query: 84 GFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVDGYLCQ 139
G+ W+ + NW P S P + CV+L +W C + GY+C+
Sbjct: 289 GWQWSDRSPF-RYLNWL-PGSPSAEPGKSCVSLNPGKNAKWENLECVQKL-GYICK 341
Score = 42.0 bits (98), Expect = 0.004
Identities = 29/127 (22%), Positives = 42/127 (32%), Gaps = 13/127 (10%)
Query: 13 PSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQ 72
Y R + +A C +G L + + E+ + V + WIGL R
Sbjct: 1243 GHCYYIESSYTRNWGQASLECLRMGSSLVSIESAAESSFLSYRVEPLKSKTNFWIGLFRN 1302
Query: 73 ARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLA 132
+ W +F NW G CVAL AS W C +
Sbjct: 1303 V-EGTWL-------WINNSP-VSFVNWNTGDPSGERN--DCVALHASS-GFWSNIHC-SS 1349
Query: 133 VDGYLCQ 139
GY+C+
Sbjct: 1350 YKGYICK 1356
Score = 35.0 bits (80), Expect = 0.57
Identities = 33/130 (25%), Positives = 46/130 (35%), Gaps = 14/130 (10%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQ 75
CY + TF EA + C L T E + S VG P + W GL +
Sbjct: 515 CYMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVGLRP-EKYFWTGLSDIQTK 573
Query: 76 CQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALE-ASGEHRWLEGSCTLAVD 134
F W T +++ FT+W S P CVA+ W C
Sbjct: 574 GT-------FQW-TIEEEVRFTHW---NSDMPGRKPGCVAMRTGIAGGLWDVLKCDEKAK 622
Query: 135 GYLCQFGFEG 144
++C+ EG
Sbjct: 623 -FVCKHWAEG 631
>ref|XP_005830.1| mannose receptor, C type 1 [Homo sapiens]
Length = 1189
Score = 158 bits (397), Expect = 3e-38
Identities = 41/144 (28%), Positives = 66/144 (45%), Gaps = 18/144 (12%)
Query: 1 DPWAAEPRAACGPSSCYALFPR----RRTFLEAWRACRELGGDLATPRTPEEAQRVDSLV 56
+ W A R S C+ L+ + ++T+ E+ CR LGGDLA+ EE Q + L+
Sbjct: 381 EDWGASSRT----SLCFKLYAKGKHEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLI 436
Query: 57 GA-GPASRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVA 115
A G +L W+GL + P GFTW+ G ++ NWA + C
Sbjct: 437 TASGSYHKLFWLGLTYGS-------PSEGFTWSDGSP-VSYENWAYGEPNNYQNVEYCGE 488
Query: 116 LEASGEHRWLEGSCTLAVDGYLCQ 139
L+ W + +C ++ ++CQ
Sbjct: 489 LKGDPTMSWNDINCE-HLNNWICQ 511
Score = 58.8 bits (141), Expect = 4e-08
Identities = 25/117 (21%), Positives = 44/117 (37%), Gaps = 11/117 (9%)
Query: 23 RRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQCQLQRPL 82
+ T A C+ GDL + ++ E + + V A +IGL L
Sbjct: 551 KETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGL--------LISLD 602
Query: 83 RGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVDGYLCQ 139
+ F W G + + +WA + CV + S W + +C + ++CQ
Sbjct: 603 KKFAWMDGSK-VDYVSWATGEPNFANEDENCVTMY-SNSGFWNDINCGYP-NAFICQ 656
Score = 54.1 bits (129), Expect = 1e-06
Identities = 32/138 (23%), Positives = 55/138 (39%), Gaps = 23/138 (16%)
Query: 14 SSCYALF----PRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGL 69
+ C+ +F R+ + EA +AC GG+L + + +E + + S W GL
Sbjct: 687 NKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSA--WTGL 744
Query: 70 QRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQR-----CVALEASGE--- 121
+ F WT G + +TNW + GG + CV +
Sbjct: 745 NDVNSEHT-------FLWTDG-RGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEA 796
Query: 122 HRWLEGSCTLAVDGYLCQ 139
+W++ +C GY+CQ
Sbjct: 797 GKWMDDTCDSK-RGYICQ 813
Score = 51.4 bits (122), Expect = 5e-06
Identities = 35/126 (27%), Positives = 53/126 (41%), Gaps = 13/126 (10%)
Query: 16 CYALFPR-RRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQAR 74
CY + ++ +A CR+ G DLA+ T EE + S +G P L WIGL
Sbjct: 106 CYKIHRDEKKIQRDALTTCRKEGSDLASIHTIEEFDFIISQLGYEPNDEL-WIGLNDIKI 164
Query: 75 QCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCP-AQRCVALEASGEHRWLEGSCTLAV 133
Q F W+ G T FT W + + CV ++ + W + C +
Sbjct: 165 QMY-------FEWSDGTPVT-FTKWLRGEPSHENNRQEDCVVMKGK-DGYWADRGCEWPL 215
Query: 134 DGYLCQ 139
GY+C+
Sbjct: 216 -GYICK 220
Score = 42.0 bits (98), Expect = 0.004
Identities = 29/127 (22%), Positives = 42/127 (32%), Gaps = 13/127 (10%)
Query: 13 PSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQ 72
Y R + +A C +G L + + E+ + V + WIGL R
Sbjct: 976 GHCYYIESSYTRNWGQASLECLRMGSSLVSIESAAESSFLSYRVEPLKSKTNFWIGLFRN 1035
Query: 73 ARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLA 132
+ W +F NW G CVAL AS W C +
Sbjct: 1036 V-EGTWL-------WINNSP-VSFVNWNTGDPSGERN--DCVALHASS-GFWSNIHC-SS 1082
Query: 133 VDGYLCQ 139
GY+C+
Sbjct: 1083 YKGYICK 1089
Score = 41.3 bits (96), Expect = 0.007
Identities = 20/81 (24%), Positives = 31/81 (37%), Gaps = 10/81 (12%)
Query: 59 GPASRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEA 118
+ LWIGL + G+ W+ + NW P S P + CV+L
Sbjct: 4 SSLTSGLWIGLNSLSFN-------SGWQWSDRSPF-RYLNWL-PGSPSAEPGKSCVSLNP 54
Query: 119 SGEHRWLEGSCTLAVDGYLCQ 139
+W C + GY+C+
Sbjct: 55 GKNAKWENLECVQKL-GYICK 74
Score = 34.6 bits (79), Expect = 0.64
Identities = 33/130 (25%), Positives = 46/130 (35%), Gaps = 14/130 (10%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQ 75
CY + TF EA + C L T E + S VG P + W GL +
Sbjct: 248 CYMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVGLRP-EKYFWTGLSDIQTK 306
Query: 76 CQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALE-ASGEHRWLEGSCTLAVD 134
F W T +++ FT+W S P CVA+ W C
Sbjct: 307 GT-------FQW-TIEEEVRFTHW---NSDMPGRKPGCVAMRTGIAGGLWDVLKCDEKAK 355
Query: 135 GYLCQFGFEG 144
++C+ EG
Sbjct: 356 -FVCKHWAEG 364
>pdb|1EGG|A Chain A, Structure Of A C-Type Carbohydrate-Recognition Domain
(Crd- 4) From The Macrophage Mannose Receptor
pdb|1EGG|B Chain B, Structure Of A C-Type Carbohydrate-Recognition Domain
(Crd- 4) From The Macrophage Mannose Receptor
pdb|1EGI|A Chain A, Structure Of A C-Type Carbohydrate-Recognition Domain
(Crd- 4) From The Macrophage Mannose Receptor
pdb|1EGI|B Chain B, Structure Of A C-Type Carbohydrate-Recognition Domain
(Crd- 4) From The Macrophage Mannose Receptor
Length = 147
Score = 151 bits (380), Expect = 4e-36
Identities = 41/144 (28%), Positives = 66/144 (45%), Gaps = 18/144 (12%)
Query: 1 DPWAAEPRAACGPSSCYALFPR----RRTFLEAWRACRELGGDLATPRTPEEAQRVDSLV 56
+ W A R S C+ L+ + ++T+ E+ CR LGGDLA+ EE Q + L+
Sbjct: 7 EDWGASSRT----SLCFKLYAKGKHEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLI 62
Query: 57 GA-GPASRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVA 115
A G +L W+GL + P GFTW+ G ++ NWA + C
Sbjct: 63 TASGSYHKLFWLGLTYGS-------PSEGFTWSDGSP-VSYENWAYGEPNNYQNVEYCGE 114
Query: 116 LEASGEHRWLEGSCTLAVDGYLCQ 139
L+ W + +C ++ ++CQ
Sbjct: 115 LKGDPTMSWNDINCE-HLNNWICQ 137
>pir||A48925 mannose receptor precursor, macrophage - mouse
Length = 1455
Score = 143 bits (358), Expect = 1e-33
Identities = 34/144 (23%), Positives = 66/144 (45%), Gaps = 18/144 (12%)
Query: 1 DPWAAEPRAACGPSSCYALFPR----RRTFLEAWRACRELGGDLATPRTPEEAQRVDSLV 56
+ W + S C+ L+ + ++T+ E+ C+ +GG+LA+ ++ +E Q + L+
Sbjct: 647 ENWGTTSKT----SMCFKLYAKGKHEKKTWFESRDFCKAIGGELASIKSKDEQQVIWRLI 702
Query: 57 G-AGPASRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVA 115
+G L W+GL + P GFTW+ G ++ NWA + C
Sbjct: 703 TSSGSYHELFWLGLTYGS-------PSEGFTWSDGSP-VSYENWAYGEPNNYQNVEYCGE 754
Query: 116 LEASGEHRWLEGSCTLAVDGYLCQ 139
L+ W + +C ++ ++CQ
Sbjct: 755 LKGDPGMSWNDINCE-HLNNWICQ 777
Score = 58.0 bits (139), Expect = 6e-08
Identities = 25/117 (21%), Positives = 45/117 (38%), Gaps = 11/117 (9%)
Query: 23 RRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQCQLQRPL 82
+ T A R C++ GDLAT ++ E + + + +IG+ L
Sbjct: 817 KETMDNARRFCKKNFGDLATIKSESEKKFLWKYINKNGGQSPYFIGM--------LISMD 868
Query: 83 RGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVDGYLCQ 139
+ F W G + F WA + CV + + W + +C + ++CQ
Sbjct: 869 KKFIWMDGSK-VDFVAWATGEPNFANDDENCVTMY-TNSGFWNDINCGYP-NNFICQ 922
Score = 54.1 bits (129), Expect = 1e-06
Identities = 36/126 (28%), Positives = 55/126 (43%), Gaps = 13/126 (10%)
Query: 16 CYALF-PRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQAR 74
CY + ++ A +ACR+ GGDLA+ + EE + S +G P L WIGL
Sbjct: 372 CYRIHREEKKIQKYALQACRKEGGDLASIHSIEEFDFIFSQLGYEPNDEL-WIGLNDIKI 430
Query: 75 QCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCP-AQRCVALEASGEHRWLEGSCTLAV 133
Q F W+ G T FT W + CV ++ + W + +C +
Sbjct: 431 QMY-------FEWSDGTPVT-FTKWLPGEPSHENNRQEDCVVMKGK-DGYWADRACEQPL 481
Query: 134 DGYLCQ 139
GY+C+
Sbjct: 482 -GYICK 486
Score = 53.7 bits (128), Expect = 1e-06
Identities = 30/138 (21%), Positives = 54/138 (38%), Gaps = 23/138 (16%)
Query: 14 SSCYALF----PRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGL 69
+ C+ +F ++++ +A +AC+ L G+L + +E V + + W GL
Sbjct: 952 NKCFKIFGFANEEKKSWQDARQACKGLKGNLVSIENAQEQAFVTYHMRDSTFNA--WTGL 1009
Query: 70 QRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQR-----CVALEASGE--- 121
+ F W T Q +TNW + GG + CV +
Sbjct: 1010 NDINAEHM-------FLW-TAGQGVHYTNWGKGYPGGRRSSLSYEDADCVVVIGGNSREA 1061
Query: 122 HRWLEGSCTLAVDGYLCQ 139
W++ +C GY+CQ
Sbjct: 1062 GTWMDDTCDSK-QGYICQ 1078
Score = 50.6 bits (120), Expect = 1e-05
Identities = 28/116 (24%), Positives = 43/116 (36%), Gaps = 13/116 (11%)
Query: 24 RTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQCQLQRPLR 83
T+ +A +C++ DL + E + L S LWIGL
Sbjct: 238 LTWHQARASCKQQNADLLSVTEIHEQMYLTGL--TSSLSSGLWIGLN-------SLSVRS 288
Query: 84 GFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVDGYLCQ 139
G+ W G + N P S P + CV+L +W C + GY+C+
Sbjct: 289 GWQWAGGSPF-RYLNL--PGSPSSEPGKSCVSLNPGKNAKWENLECVQKL-GYICK 340
Score = 41.6 bits (97), Expect = 0.005
Identities = 27/117 (23%), Positives = 42/117 (35%), Gaps = 13/117 (11%)
Query: 23 RRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQCQLQRPL 82
R++ +A C +G L + T E+ + V + WIG+ R +
Sbjct: 1251 TRSWGQASLECLRMGASLVSIETAAESSFLSYRVEPLKSKTNFWIGM---------FRNV 1301
Query: 83 RGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVDGYLCQ 139
G D +F NW G CV L AS W C + G++C+
Sbjct: 1302 EGKWLWLNDNPVSFVNWKTGDPSGERN--DCVVL-ASSSGLWNNIHC-SSYKGFICK 1354
Score = 38.9 bits (90), Expect = 0.033
Identities = 34/133 (25%), Positives = 46/133 (34%), Gaps = 14/133 (10%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQ 75
CY + TF +A C L T E + SLVG P + W GL +
Sbjct: 514 CYLIGSTLSTFTDANHTCTNEKAYLTTVEDRYEQAFLTSLVGLRP-EKYFWTGLSDVQNK 572
Query: 76 CQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALE-ASGEHRWLEGSCTLAVD 134
F W T D+ FT+W G CVA++ W SC
Sbjct: 573 GT-------FRW-TVDEQVQFTHWNADMPGRKA---GCVAMKTGVAGGLWDVLSCEEKAK 621
Query: 135 GYLCQFGFEGACP 147
++C+ EG
Sbjct: 622 -FVCKHWAEGVTR 633
>ref|NP_032651.1| mannose receptor, C type 1 [Mus musculus]
emb|CAA78028.1| (Z11974) macrophage mannose receptor precursor [Mus musculus]
Length = 1456
Score = 143 bits (358), Expect = 1e-33
Identities = 34/144 (23%), Positives = 66/144 (45%), Gaps = 18/144 (12%)
Query: 1 DPWAAEPRAACGPSSCYALFPR----RRTFLEAWRACRELGGDLATPRTPEEAQRVDSLV 56
+ W + S C+ L+ + ++T+ E+ C+ +GG+LA+ ++ +E Q + L+
Sbjct: 648 ENWGTTSKT----SMCFKLYAKGKHEKKTWFESRDFCKAIGGELASIKSKDEQQVIWRLI 703
Query: 57 G-AGPASRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVA 115
+G L W+GL + P GFTW+ G ++ NWA + C
Sbjct: 704 TSSGSYHELFWLGLTYGS-------PSEGFTWSDGSP-VSYENWAYGEPNNYQNVEYCGE 755
Query: 116 LEASGEHRWLEGSCTLAVDGYLCQ 139
L+ W + +C ++ ++CQ
Sbjct: 756 LKGDPGMSWNDINCE-HLNNWICQ 778
Score = 58.0 bits (139), Expect = 6e-08
Identities = 25/117 (21%), Positives = 45/117 (38%), Gaps = 11/117 (9%)
Query: 23 RRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQCQLQRPL 82
+ T A R C++ GDLAT ++ E + + + +IG+ L
Sbjct: 818 KETMDNARRFCKKNFGDLATIKSESEKKFLWKYINKNGGQSPYFIGM--------LISMD 869
Query: 83 RGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVDGYLCQ 139
+ F W G + F WA + CV + + W + +C + ++CQ
Sbjct: 870 KKFIWMDGSK-VDFVAWATGEPNFANDDENCVTMY-TNSGFWNDINCGYP-NNFICQ 923
Score = 55.3 bits (132), Expect = 4e-07
Identities = 29/116 (25%), Positives = 44/116 (37%), Gaps = 12/116 (10%)
Query: 24 RTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQCQLQRPLR 83
T+ +A +C++ DL + E + L S LWIGL
Sbjct: 238 LTWHQARASCKQQNADLLSVTEIHEQMYLTGL--TSSLSSGLWIGLN-------SLSVRS 288
Query: 84 GFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVDGYLCQ 139
G+ W G + NW P S P + CV+L +W C + GY+C+
Sbjct: 289 GWQWAGGSPF-RYLNWL-PGSPSSEPGKSCVSLNPGKNAKWENLECVQKL-GYICK 341
Score = 54.1 bits (129), Expect = 1e-06
Identities = 36/126 (28%), Positives = 55/126 (43%), Gaps = 13/126 (10%)
Query: 16 CYALF-PRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQAR 74
CY + ++ A +ACR+ GGDLA+ + EE + S +G P L WIGL
Sbjct: 373 CYRIHREEKKIQKYALQACRKEGGDLASIHSIEEFDFIFSQLGYEPNDEL-WIGLNDIKI 431
Query: 75 QCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCP-AQRCVALEASGEHRWLEGSCTLAV 133
Q F W+ G T FT W + CV ++ + W + +C +
Sbjct: 432 QMY-------FEWSDGTPVT-FTKWLPGEPSHENNRQEDCVVMKGK-DGYWADRACEQPL 482
Query: 134 DGYLCQ 139
GY+C+
Sbjct: 483 -GYICK 487
Score = 53.7 bits (128), Expect = 1e-06
Identities = 30/138 (21%), Positives = 54/138 (38%), Gaps = 23/138 (16%)
Query: 14 SSCYALF----PRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGL 69
+ C+ +F ++++ +A +AC+ L G+L + +E V + + W GL
Sbjct: 953 NKCFKIFGFANEEKKSWQDARQACKGLKGNLVSIENAQEQAFVTYHMRDSTFNA--WTGL 1010
Query: 70 QRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQR-----CVALEASGE--- 121
+ F W T Q +TNW + GG + CV +
Sbjct: 1011 NDINAEHM-------FLW-TAGQGVHYTNWGKGYPGGRRSSLSYEDADCVVVIGGNSREA 1062
Query: 122 HRWLEGSCTLAVDGYLCQ 139
W++ +C GY+CQ
Sbjct: 1063 GTWMDDTCDSK-QGYICQ 1079
Score = 41.6 bits (97), Expect = 0.005
Identities = 27/117 (23%), Positives = 42/117 (35%), Gaps = 13/117 (11%)
Query: 23 RRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQCQLQRPL 82
R++ +A C +G L + T E+ + V + WIG+ R +
Sbjct: 1252 TRSWGQASLECLRMGASLVSIETAAESSFLSYRVEPLKSKTNFWIGM---------FRNV 1302
Query: 83 RGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVDGYLCQ 139
G D +F NW G CV L AS W C + G++C+
Sbjct: 1303 EGKWLWLNDNPVSFVNWKTGDPSGERN--DCVVL-ASSSGLWNNIHC-SSYKGFICK 1355
Score = 38.9 bits (90), Expect = 0.033
Identities = 34/133 (25%), Positives = 46/133 (34%), Gaps = 14/133 (10%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQ 75
CY + TF +A C L T E + SLVG P + W GL +
Sbjct: 515 CYLIGSTLSTFTDANHTCTNEKAYLTTVEDRYEQAFLTSLVGLRP-EKYFWTGLSDVQNK 573
Query: 76 CQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALE-ASGEHRWLEGSCTLAVD 134
F W T D+ FT+W G CVA++ W SC
Sbjct: 574 GT-------FRW-TVDEQVQFTHWNADMPGRKA---GCVAMKTGVAGGLWDVLSCEEKAK 622
Query: 135 GYLCQFGFEGACP 147
++C+ EG
Sbjct: 623 -FVCKHWAEGVTR 634
>pdb|1HTN| Human Tetranectin, A Trimeric Plasminogen Binding Protein With An
Alpha-Helical Coiled Coil
Length = 182
Score = 133 bits (332), Expect = 1e-30
Identities = 39/147 (26%), Positives = 59/147 (39%), Gaps = 27/147 (18%)
Query: 8 RAAC-----GPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPAS 62
+ C C+ F + +TF EA C GG L+TP+T E + + +
Sbjct: 48 QTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLSTPQTGSENDALYEYLRQSVGN 107
Query: 63 RL-LWIGLQRQARQCQLQRPLRGFTWT--TGDQDTAFTNW-----AQPASGGPCPAQRCV 114
+W+GL A + TW TG + A+ NW AQP G + C
Sbjct: 108 EAEIWLGLNDMAAEG---------TWVDMTGAR-IAYKNWETEITAQPDGG---KTENCA 154
Query: 115 ALEASGEHRWLEGSCTLAVDGYLCQFG 141
L + +W + C + Y+CQFG
Sbjct: 155 VLSGAANGKWFDKRCRDQLP-YICQFG 180
>ref|NP_003269.1| tetranectin (plasminogen-binding protein) [Homo sapiens]
sp|P05452|TETN_HUMAN TETRANECTIN PRECURSOR (TN) (PLASMINOGEN-KRINGLE 4 BINDING PROTEIN)
pir||TTHUN tetranectin precursor - human
emb|CAA45860.1| (X64559) Tetranectin [Homo sapiens]
emb|CAA50265.1| (X70910) tetranectin [Homo sapiens]
Length = 202
Score = 133 bits (332), Expect = 1e-30
Identities = 39/147 (26%), Positives = 59/147 (39%), Gaps = 27/147 (18%)
Query: 8 RAAC-----GPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPAS 62
+ C C+ F + +TF EA C GG L+TP+T E + + +
Sbjct: 68 QTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLSTPQTGSENDALYEYLRQSVGN 127
Query: 63 RL-LWIGLQRQARQCQLQRPLRGFTWT--TGDQDTAFTNW-----AQPASGGPCPAQRCV 114
+W+GL A + TW TG + A+ NW AQP G + C
Sbjct: 128 EAEIWLGLNDMAAEG---------TWVDMTGAR-IAYKNWETEITAQPDGG---KTENCA 174
Query: 115 ALEASGEHRWLEGSCTLAVDGYLCQFG 141
L + +W + C + Y+CQFG
Sbjct: 175 VLSGAANGKWFDKRCRDQLP-YICQFG 200
>pdb|1TN3| The C-Type Lectin Carbohydrate Recognition Domain Of Human
Tetranectin
Length = 137
Score = 128 bits (320), Expect = 4e-29
Identities = 39/147 (26%), Positives = 59/147 (39%), Gaps = 27/147 (18%)
Query: 8 RAAC-----GPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPAS 62
+ C C+ F + +TF EA C GG L+TP+T E + + +
Sbjct: 3 QTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLSTPQTGSENDALYEYLRQSVGN 62
Query: 63 RL-LWIGLQRQARQCQLQRPLRGFTWT--TGDQDTAFTNW-----AQPASGGPCPAQRCV 114
+W+GL A + TW TG + A+ NW AQP G + C
Sbjct: 63 EAEIWLGLNDMAAEG---------TWVDMTGAR-IAYKNWETEITAQPDGG---KTENCA 109
Query: 115 ALEASGEHRWLEGSCTLAVDGYLCQFG 141
L + +W + C + Y+CQFG
Sbjct: 110 VLSGAANGKWFDKRCRDQLP-YICQFG 135
>ref|NP_035736.1| tetranectin (plasminogen-binding protein) [Mus musculus]
sp|P43025|TETN_MOUSE TETRANECTIN PRECURSOR (TN) (PLASMINOGEN-KRINGLE 4 BINDING PROTEIN)
pir||JC4031 tetranectin precursor - mouse
emb|CAA55791.1| (X79199) tetranectin [Mus musculus]
emb|CAA66804.1| (X98122) murine tetranectin [Mus musculus]
Length = 202
Score = 109 bits (270), Expect = 3e-23
Identities = 37/146 (25%), Positives = 55/146 (37%), Gaps = 27/146 (18%)
Query: 8 RAAC-----GPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPAS 62
+ C C F + +TF EA C GG L TP++ E + + +
Sbjct: 68 QTVCLKGTKVNLKCLLAFTQPKTFHEASEDCISQGGTLGTPQSELENEALFEYARHSVGN 127
Query: 63 RL-LWIGLQRQARQCQLQRPLRGFTWT--TGDQDTAFTNW-----AQPASGGPCPAQRCV 114
+W+GL A + W TG A+ NW QP G A+ C
Sbjct: 128 DANIWLGLNDMAAEG---------AWVDMTGG-LLAYKNWETEITTQPDGG---KAENCA 174
Query: 115 ALEASGEHRWLEGSCTLAVDGYLCQF 140
AL + +W + C + Y+CQF
Sbjct: 175 ALSGAANGKWFDKRCRDQLP-YICQF 199
>gb|AAA96811.1| (U08595) tetranectin [Mus musculus]
Length = 202
Score = 107 bits (265), Expect = 1e-22
Identities = 37/146 (25%), Positives = 55/146 (37%), Gaps = 27/146 (18%)
Query: 8 RAAC-----GPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPAS 62
+ C C F + +TF EA C GG L TP++ E + + +
Sbjct: 68 QTVCLKGTKVNLKCLLTFTQPKTFHEASEDCISQGGTLGTPQSELENEALFEYARHSVGN 127
Query: 63 RL-LWIGLQRQARQCQLQRPLRGFTWT--TGDQDTAFTNW-----AQPASGGPCPAQRCV 114
+W+GL A + W TG A+ NW QP G A+ C
Sbjct: 128 DANIWLGLNDMAAEG---------AWVDMTGG-LLAYKNWETEITTQPDGG---KAENCA 174
Query: 115 ALEASGEHRWLEGSCTLAVDGYLCQF 140
AL + +W + C + Y+CQF
Sbjct: 175 ALSGARNGKWFDKQCRDQLP-YICQF 199
>ref|NP_005743.1| C-type (calcium dependent, carbohydrate-recognition domain) lectin,
superfamily member 1 (cartilage-derived);
cartilage-derived C-type lectin (similar to tetranectin)
[Homo sapiens]
gb|AAD12542.1| (AF077345) cartilage-derived C-type lectin [Homo sapiens]
Length = 197
Score = 75.5 bits (184), Expect = 3e-13
Identities = 32/144 (22%), Positives = 50/144 (34%), Gaps = 20/144 (13%)
Query: 8 RAAC-----GPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSL-VGAGPA 61
+ C CY + F EA C GG L PR +E + + P
Sbjct: 65 QTVCLRGTKVHKKCYLASEGLKHFHEANEDCISKGGILVIPRNSDEINALQDYGKRSLPG 124
Query: 62 SRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNW--AQPASGGPCPAQRCVALEAS 119
W+G+ + + G +F NW AQP G + CV S
Sbjct: 125 VNDFWLGINDMVTEGKFVD-------VNGI-AISFLNWDRAQPNGG---KRENCVLFSQS 173
Query: 120 GEHRWLEGSCTLAVDGYLCQFGFE 143
+ +W + +C + Y+C+F
Sbjct: 174 AQGKWSDEACRSS-KRYICEFTIP 196
>sp|P26258|TETN_CARSP TETRANECTIN-LIKE PROTEIN
pir||A37289 tetranectin homolog - reef shark
gb|AAB27084.1| tetranectin homolog [Carcharhinus springeri=reef sharks, neural
arch cartilage, Peptide, 166 aa]
Length = 166
Score = 72.8 bits (177), Expect = 2e-12
Identities = 29/128 (22%), Positives = 50/128 (38%), Gaps = 15/128 (11%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAG-PASRLLWIGLQRQAR 74
CY +++ A C GG L+ PR+ +E + S +R WIG+
Sbjct: 47 CYLASRGSKSYHAANEDCIAQGGTLSIPRSSDEGNSLRSYAKKSLVGARDFWIGVNDMTT 106
Query: 75 QCQLQRPLRGFTWTTGDQDTAFTNW--AQPASGGPCPAQRCVALEASGEHRWLEGSCTLA 132
+ + G + NW ++P G + CVA SG+ +W + C
Sbjct: 107 EGKFVD-------VNGLP-ITYFNWDRSKPVGGTR---ENCVAASTSGQGKWSDDVCRSE 155
Query: 133 VDGYLCQF 140
Y+C++
Sbjct: 156 -KRYICEY 162
>gb|AAC18614.1| (U22298) C-type lectin homolog precursor [Bos taurus]
Length = 197
Score = 71.2 bits (173), Expect = 6e-12
Identities = 29/131 (22%), Positives = 47/131 (35%), Gaps = 15/131 (11%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSL-VGAGPASRLLWIGLQRQAR 74
CY + F EA C GG L PR+ +E + + P W+G+
Sbjct: 78 CYLAAEGLKHFHEANEDCISKGGTLVVPRSADEINALRDYGKRSLPGVNDFWLGINDMVA 137
Query: 75 QCQLQRPLRGFTWTTGDQDTAFTNW--AQPASGGPCPAQRCVALEASGEHRWLEGSCTLA 132
+ + +F NW AQP G + C S + +W + +C +
Sbjct: 138 EGKFVD--------INGLAISFLNWDQAQPNGG---KRENCALFSQSAQGKWSDEACHSS 186
Query: 133 VDGYLCQFGFE 143
Y+C+F
Sbjct: 187 -KRYICEFTIP 196
>sp|P06734|FCE2_HUMAN LOW AFFINITY IMMUNOGLOBULIN EPSILON FC RECEPTOR (LYMPHOCYTE IGE
RECEPTOR) (FC-EPSILON-RII) (CD23) (BLAST-2)
(IMMUNOGLOBULIN E-BINDING FACTOR)
pir||LNHUER IgE Fc receptor II, low-affinity [validated] - human
gb|AAA52434.1| (M15059) Fc-epsilon receptor old gene name 'FCE1A' [Homo sapiens]
gb|AAA52435.1| (M14766) Fc-epsilon receptor old gene name 'FCE1A' [Homo sapiens]
Length = 321
Score = 70.5 bits (171), Expect = 1e-11
Identities = 32/138 (23%), Positives = 51/138 (36%), Gaps = 18/138 (13%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQ 75
CY + ++ A AC ++ G L + +PEE + + WIGL+
Sbjct: 174 CYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQD----FLTKHASHTGSWIGLR----- 224
Query: 76 CQLQRPLRG-FTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVD 134
L+G F W G ++NWA + CV + SG RW + C +
Sbjct: 225 ---NLDLKGEFIWVDGS-HVDYSNWAPGEPTSRSQGEDCVMMRGSG--RWNDAFCDRKLG 278
Query: 135 GYLCQFGFEGACPALQDE 152
++C C E
Sbjct: 279 AWVCD--RLATCTPPASE 294
>ref|NP_001993.1| Fc fragment of IgE, low affinity II, receptor for (CD23A) [Homo
sapiens]
emb|CAA28465.1| (X04772) IgE receptor (AA 1-321) [Homo sapiens]
Length = 321
Score = 68.9 bits (167), Expect = 3e-11
Identities = 32/138 (23%), Positives = 51/138 (36%), Gaps = 18/138 (13%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQ 75
CY + ++ A AC ++ G L + +PEE + + WIGL+
Sbjct: 174 CYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQD----FLTKHASHTGSWIGLR----- 224
Query: 76 CQLQRPLRG-FTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVD 134
L+G F W G ++NWA + CV + SG RW + C +
Sbjct: 225 ---NLDLKGEFIWVDGS-HVDYSNWAPGEPTSRSQGEDCVMMRGSG--RWTDAFCDRKLG 278
Query: 135 GYLCQFGFEGACPALQDE 152
++C C E
Sbjct: 279 AWVCD--RLATCTPPASE 294
>emb|CAA45533.1| (X64224) Fc-E receptor II (Fc-ERII/CD23) [Mus musculus]
Length = 330
Score = 68.5 bits (166), Expect = 4e-11
Identities = 27/124 (21%), Positives = 51/124 (40%), Gaps = 14/124 (11%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQ 75
CY + +++A AC +L G L + + +E + + + WIGLQ +
Sbjct: 196 CYYFGKGSKQWIQARFACSDLQGRLVSIHSQKEQDFLMQHINK----KDSWIGLQDLNME 251
Query: 76 CQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVDG 135
+ F W+ G ++NW + CV + SG+ W + C +D
Sbjct: 252 GE-------FVWSDGSP-VGYSNWNPGEPNNGGQGEDCVMMRGSGQ--WNDAFCRSYLDA 301
Query: 136 YLCQ 139
++C+
Sbjct: 302 WVCE 305
>ref|NP_031555.1| brevican [Mus musculus]
sp|Q61361|PGCB_MOUSE BREVICAN CORE PROTEIN PRECURSOR
pir||S57653 brevican precursor - mouse
emb|CAA60575.1| (X87096) brevican [Mus musculus]
Length = 883
Score = 68.5 bits (166), Expect = 4e-11
Identities = 36/142 (25%), Positives = 52/142 (36%), Gaps = 15/142 (10%)
Query: 15 SCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQAR 74
+CY F RR++ EA CR LG L + TPEE V+ WIGL +
Sbjct: 674 ACYKHFSTRRSWEEAESQCRALGAHLTSICTPEEQDFVND-----RYREYQWIGLNDRTI 728
Query: 75 QCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGP-CPAQRCVALEASGEHRWLEGSCTLAV 133
+ F W+ G + NW + CV + + +W + C +
Sbjct: 729 EGD-------FLWSDGAPLL-YENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYHL 780
Query: 134 DGYLCQFGFEGACPALQDEAGQ 155
Y C+ G P Q Q
Sbjct: 781 -SYTCKMGLVSCGPPPQLPLAQ 801
>ref|NP_038545.1| Fc receptor, IgE, low affinity II, alpha polypeptide; FC epsilon
RII; low-affinity IgE receptor [Mus musculus]
sp|P20693|FCE2_MOUSE LOW AFFINITY IMMUNOGLOBULIN EPSILON FC RECEPTOR (LYMPHOCYTE IGE
RECEPTOR) (FC-EPSILON-RII) (CD23)
pir||LNMSER IgE Fc receptor, low-affinity - mouse
gb|AAA74898.1| (M99371) IgE low affinity receptor [Mus musculus]
gb|AAA37603.1| (M34163) low affinity IgE receptor (Fc-epsilon-RII) [Mus musculus]
Length = 331
Score = 68.5 bits (166), Expect = 4e-11
Identities = 27/124 (21%), Positives = 51/124 (40%), Gaps = 14/124 (11%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQ 75
CY + +++A AC +L G L + + +E + + + WIGLQ +
Sbjct: 197 CYYFGKGSKQWIQARFACSDLQGRLVSIHSQKEQDFLMQHINK----KDSWIGLQDLNME 252
Query: 76 CQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVDG 135
+ F W+ G ++NW + CV + SG+ W + C +D
Sbjct: 253 GE-------FVWSDGSP-VGYSNWNPGEPNNGGQGEDCVMMRGSGQ--WNDAFCRSYLDA 302
Query: 136 YLCQ 139
++C+
Sbjct: 303 WVCE 306
>sp|Q28062|PGCB_BOVIN BREVICAN CORE PROTEIN PRECURSOR
pir||A54423 brevican precursor - bovine
emb|CAA53481.1| (X75887) brevican [Bos taurus]
Length = 912
Score = 68.5 bits (166), Expect = 5e-11
Identities = 33/135 (24%), Positives = 50/135 (36%), Gaps = 15/135 (11%)
Query: 15 SCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQAR 74
+CY F RR++ EA CR G LA+ TPEE ++ WIGL +
Sbjct: 699 ACYKHFSARRSWEEAENKCRMYGAHLASISTPEEQDFIN-----NRYREYQWIGLNDRTI 753
Query: 75 QCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGP-CPAQRCVALEASGEHRWLEGSCTLAV 133
+ F W+ G + NW + CV + + +W + C +
Sbjct: 754 EGD-------FLWSDGVPLL-YENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYHL 805
Query: 134 DGYLCQFGFEGACPA 148
Y C+ G P
Sbjct: 806 -SYTCKMGLVSCGPP 819
>gb|AAA87847.1| (U37142) brevican core protein [Rattus norvegicus]
Length = 883
Score = 68.5 bits (166), Expect = 5e-11
Identities = 36/142 (25%), Positives = 52/142 (36%), Gaps = 15/142 (10%)
Query: 15 SCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQAR 74
+CY F RR++ EA CR LG L + TPEE V+ WIGL +
Sbjct: 674 ACYKHFSTRRSWEEAESQCRALGAHLTSICTPEEQDFVND-----RYREYQWIGLNDRTI 728
Query: 75 QCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGP-CPAQRCVALEASGEHRWLEGSCTLAV 133
+ F W+ G + NW + CV + + +W + C +
Sbjct: 729 EGD-------FLWSDGAPLL-YENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYHL 780
Query: 134 DGYLCQFGFEGACPALQDEAGQ 155
Y C+ G P Q Q
Sbjct: 781 -SYTCKMGLVSCGPPPQLPLAQ 801
>emb|CAA45532.1| (X64223) Fc-E receptor II (Fc-ERII/CD23) [Mus musculus]
Length = 330
Score = 68.5 bits (166), Expect = 5e-11
Identities = 27/124 (21%), Positives = 51/124 (40%), Gaps = 14/124 (11%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQ 75
CY + +++A AC +L G L + + +E + + + WIGLQ +
Sbjct: 196 CYYFGKGSKQWIQARFACSDLQGRLVSIHSQKEQDFLMQHINK----KDSWIGLQDLNME 251
Query: 76 CQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVDG 135
+ F W+ G ++NW + CV + SG+ W + C +D
Sbjct: 252 GE-------FVWSDGSP-VGYSNWNPGEPNNGGQGEDCVMMRGSGQ--WNDAFCRSYLDA 301
Query: 136 YLCQ 139
++C+
Sbjct: 302 WVCE 305
>sp|P55067|PGCN_RAT NEUROCAN CORE PROTEIN PRECURSOR (245 KDA EARLY POSTNATAL CORE
GLYCOPROTEIN) [CONTAINS: 150 KDA ADULT CORE GLYCOPROTEIN]
pir||S28764 neurocan precursor - rat
gb|AAC37679.1| (M97161) neurocan [Rattus norvegicus]
Length = 1257
Score = 67.4 bits (163), Expect = 8e-11
Identities = 35/138 (25%), Positives = 53/138 (38%), Gaps = 15/138 (10%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQ 75
CY F RR + +A R CR G L + +PEE + ++ WIGL + +
Sbjct: 1040 CYRYFAHRRAWEDAERDCRRRAGHLTSVHSPEEHKFIN-----SFGHENSWIGLNDRTVE 1094
Query: 76 CQLQRPLRGFTWTTGDQDTAFTNW-AQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVD 134
R F WT + + NW + + CV + A RW + C +
Sbjct: 1095 -------RDFQWTD-NTGLQYENWREKQPDNFFAGGEDCVVMVAHENGRWNDVPCNYNLP 1146
Query: 135 GYLCQFGFEGACPALQDE 152
Y+C+ G P E
Sbjct: 1147 -YVCKKGTVLCGPPPAVE 1163
>sp|P55068|PGCB_RAT BREVICAN CORE PROTEIN PRECURSOR (BRAIN ENRICHED HYALURONAN BINDING
PROTEIN) (BEHAB PROTEIN)
pir||S49126 brevican precursor - rat
emb|CAA56255.1| (X79881) aggrecan like protein/ brevican [Rattus norvegicus]
Length = 883
Score = 67.4 bits (163), Expect = 1e-10
Identities = 36/142 (25%), Positives = 52/142 (36%), Gaps = 15/142 (10%)
Query: 15 SCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQAR 74
+CY F RR++ EA CR LG L + TPEE V+ WIGL +
Sbjct: 674 ACYKHFSTRRSWEEAESQCRALGAHLTSICTPEEQDFVND-----RYREYQWIGLNDRTI 728
Query: 75 QCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGP-CPAQRCVALEASGEHRWLEGSCTLAV 133
+ F W+ G + NW + CV + + +W + C +
Sbjct: 729 EGD-------FLWSDG-PPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYHL 780
Query: 134 DGYLCQFGFEGACPALQDEAGQ 155
Y C+ G P Q Q
Sbjct: 781 -SYTCKMGLVSCGPPPQLPLAQ 801
>ref|NP_035166.1| pancreatitis-associated protein; RegIII (beta) [Mus musculus]
sp|P35230|PAP1_MOUSE PANCREATITIS-ASSOCIATED PROTEIN 1 PRECURSOR (REG III-BETA)
pir||S29822 pancreatitis-associated protein - mouse
dbj|BAA02727.1| (D13509) PAP homologous protein [Mus musculus]
dbj|BAA18928.1| (D63359) regIIIbeta/PAP protein [Mus musculus]
dbj|BAA18929.1| (D63360) regIIIbeta/PAP protein [Mus musculus]
Length = 175
Score = 67.0 bits (162), Expect = 1e-10
Identities = 37/135 (27%), Positives = 61/135 (44%), Gaps = 8/135 (5%)
Query: 9 AACGPSSCYALFPRRRTFLEAWRACREL-GGDLATPRTPEEAQRVDSLV-GAGPASRLLW 66
+ S CYALF +T+ +A AC++ GG L + EA + S+V G + + W
Sbjct: 44 SQAYGSYCYALFQIPQTWFDAELACQKRPGGHLVSVLNSAEASFLSSMVKRTGNSYQYTW 103
Query: 67 IGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALE-ASGEHRWL 125
IGL + G+ W+ D + NW + C +L ASG +W
Sbjct: 104 IGLHDPTLGAEPNG--GGWEWSNND-VMNYFNWER-NPSTALDRAFCGSLSRASGFLKWR 159
Query: 126 EGSCTLAVDGYLCQF 140
+ +C + + Y+C+F
Sbjct: 160 DMTCEVKLP-YVCKF 173
>dbj|BAA95671.1| (AB034807) C-type lectin [Cyprinus carpio]
Length = 163
Score = 66.6 bits (161), Expect = 2e-10
Identities = 28/126 (22%), Positives = 52/126 (41%), Gaps = 12/126 (9%)
Query: 13 PSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQ 72
CY F R +++ A R C E +LA+ EE + L+ ++ W+G+Q
Sbjct: 35 GVQCYKFFSRSTSWIAAERNCIEEHANLASVHNEEENDFLMGLLP--STTKRCWLGVQDA 92
Query: 73 ARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLA 132
+ Q W+ G ++NW + C + + + W + SC+ +
Sbjct: 93 VEEGQWL-------WSDGTPY-DYSNWCSNEPNN-LNVENCGEINWTSDRCWNDASCSTS 143
Query: 133 VDGYLC 138
+ GY+C
Sbjct: 144 M-GYVC 148
>ref|NP_031815.1| chondroitin sulfate proteoglycan 3 [Mus musculus]
sp|P55066|PGCN_MOUSE NEUROCAN CORE PROTEIN PRECURSOR
pir||S52781 neurocan - mouse
emb|CAA59216.1| (X84727) neurocan [Mus musculus]
Length = 1268
Score = 66.2 bits (160), Expect = 2e-10
Identities = 35/138 (25%), Positives = 53/138 (38%), Gaps = 15/138 (10%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQ 75
CY F RR + +A R CR G L + +PEE + ++ WIGL + +
Sbjct: 1051 CYRYFAHRRAWEDAERDCRRRAGHLTSVHSPEEHKFIN-----SFGHENSWIGLNDRTVE 1105
Query: 76 CQLQRPLRGFTWTTGDQDTAFTNW-AQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVD 134
R F WT + + NW + + CV + A RW + C +
Sbjct: 1106 -------RDFQWTD-NTGLQYENWREKQPDNFFAGGEDCVVMVAHESGRWNDVPCNYNLP 1157
Query: 135 GYLCQFGFEGACPALQDE 152
Y+C+ G P E
Sbjct: 1158 -YVCKKGTVLCGPPPAVE 1174
>ref|NP_068767.1| chondroitin sulfate proteoglycan BEHAB/brevican [Homo sapiens]
gb|AAG23134.1|AF228710_1 (AF228710) chondroitin sulfate proteoglycan BEHAB/brevican [Homo
sapiens]
Length = 911
Score = 66.2 bits (160), Expect = 2e-10
Identities = 33/135 (24%), Positives = 50/135 (36%), Gaps = 15/135 (11%)
Query: 15 SCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQAR 74
+CY F RR++ EA CR G LA+ TPEE ++ WIGL +
Sbjct: 698 ACYKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFIN-----NRYREYQWIGLNDRTI 752
Query: 75 QCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGP-CPAQRCVALEASGEHRWLEGSCTLAV 133
+ F W+ G + NW + CV + + +W + C +
Sbjct: 753 EGD-------FLWSDGVPLL-YENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYHL 804
Query: 134 DGYLCQFGFEGACPA 148
Y C+ G P
Sbjct: 805 -SYTCKMGLVSCGPP 818
>pir||JC7134 agkisacutacin alpha chain precursor [accepted] - sharp-nosed viper
Length = 152
Score = 65.4 bits (158), Expect = 3e-10
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 18/129 (13%)
Query: 16 CYALFPRRRTFLEAWRAC--RELGGDLATPRTPEEAQRVDSLVGAGPASRLL--WIGLQR 71
CY +F + +T+ +A C + GG L + + EA V L+ S + WIGL+
Sbjct: 36 CYKVFKQSKTWADAESFCTKQVNGGHLVSIESSGEADFVAHLIAQKIKSAKIHVWIGLRA 95
Query: 72 QARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALE-ASGEHRWLEGSCT 130
Q ++ Q W+ G ++ NW + S ++C+ + +G H+W C
Sbjct: 96 QNKEKQCS-----IEWSDGS-SISYENWIEEES------KKCLGVHIETGFHKWENFYCE 143
Query: 131 LAVDGYLCQ 139
D ++C+
Sbjct: 144 QQ-DPFVCE 151
>gb|AAF71144.1|AF141931_1 (AF141931) low-affinity IgE receptor; CD23 [Equus caballus]
Length = 326
Score = 65.4 bits (158), Expect = 4e-10
Identities = 28/123 (22%), Positives = 48/123 (38%), Gaps = 14/123 (11%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQ 75
CY + +++A AC +L G L + + EE + + WIGL+ +
Sbjct: 212 CYYFGEGPKRWIQARFACSKLHGRLVSIHSQEEQDFLTRHANK----KGSWIGLRDLNIE 267
Query: 76 CQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVDG 135
+ F W ++NW + CV + ASG W + C +DG
Sbjct: 268 GE-------FVWMD-QNPLDYSNWQPGEPNNGGQGEDCVMMRASGH--WNDAFCGSYLDG 317
Query: 136 YLC 138
++C
Sbjct: 318 WVC 320
>prf||1908220B pancreatitis-associated protein [Mus musculus]
Length = 175
Score = 65.0 bits (157), Expect = 5e-10
Identities = 37/135 (27%), Positives = 61/135 (44%), Gaps = 8/135 (5%)
Query: 9 AACGPSSCYALFPRRRTFLEAWRACREL-GGDLATPRTPEEAQRVDSLV-GAGPASRLLW 66
+ S CYALF +T+ +A AC++ GG L + EA + S+V G + + W
Sbjct: 44 SQAYGSYCYALFQIPQTWFDAELACQKRPGGHLVSVLNSAEASFLSSMVKRTGNSYQYTW 103
Query: 67 IGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALE-ASGEHRWL 125
IGL + G+ W+ D + NW + C +L ASG +W
Sbjct: 104 IGLHDPTLGAEPNG--GGWEWSNND-VMNYFNWER-NPSTALDRAFCGSLSRASGFLKWR 159
Query: 126 EGSCTLAVDGYLCQF 140
+ +C + + Y+C+F
Sbjct: 160 DMTCNVKLP-YVCKF 173
>gb|AAF22145.2|AF132496_1 (AF132496) lung surfactant protein D precursor; SPD; SP-D; CP4 [Sus
scrofa]
Length = 378
Score = 63.8 bits (154), Expect = 1e-09
Identities = 28/137 (20%), Positives = 55/137 (39%), Gaps = 16/137 (11%)
Query: 7 PRAACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLW 66
P + +TF +A + C + GG +A+PR+ E + + LV A ++ +
Sbjct: 255 PNGRGVGEKIFKTGGFEKTFQDAQQVCTQAGGQMASPRSETENEALSQLVTA--QNKAAF 312
Query: 67 IGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGG---PCPAQRCVALEASGEHR 123
+ + + FT+ TG+ + NWA A+ CV + +
Sbjct: 313 LSMTDIKTEGN-------FTYPTGEPLV-YANWAPGEPNNNGGSSGAENCVEIFP--NGK 362
Query: 124 WLEGSCTLAVDGYLCQF 140
W + +C + +C+F
Sbjct: 363 WNDKACG-ELRLVICEF 378
>gb|AAD24546.2| (AF116856) neurocan core protein precursor [Gallus gallus]
Length = 1290
Score = 63.5 bits (153), Expect = 1e-09
Identities = 30/125 (24%), Positives = 49/125 (39%), Gaps = 15/125 (12%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQ 75
CY F RRR++ +A R CR G L + + EE ++ WIGL + +
Sbjct: 1067 CYRYFSRRRSWEDAERDCRRRAGHLTSIHSQEEHGFIN-----SFGHENTWIGLNDRIVE 1121
Query: 76 CQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCP-AQRCVALEASGEHRWLEGSCTLAVD 134
F WT + + NW + + CV L + +W + C +
Sbjct: 1122 QD-------FQWTD-NTGLQYENWRENQPDNFFAGGEDCVVLVSHEIGKWNDVPCNYNLP 1173
Query: 135 GYLCQ 139
Y+C+
Sbjct: 1174 -YICK 1177
>pir||T46256 brevican - human (fragment)
emb|CAB70776.1| (AL137504) hypothetical protein [Homo sapiens]
Length = 330
Score = 63.5 bits (153), Expect = 1e-09
Identities = 33/135 (24%), Positives = 50/135 (36%), Gaps = 15/135 (11%)
Query: 15 SCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQAR 74
+CY F RR++ EA CR G LA+ TPEE ++ WIGL +
Sbjct: 117 ACYKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFIN-----NRYREYQWIGLNDRTI 171
Query: 75 QCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGP-CPAQRCVALEASGEHRWLEGSCTLAV 133
+ F W+ G + NW + CV + + +W + C +
Sbjct: 172 EGD-------FLWSDGVPLL-YENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYHL 223
Query: 134 DGYLCQFGFEGACPA 148
Y C+ G P
Sbjct: 224 -SYTCKMGLVSCGPP 237
>pir||S33603 surfactant protein D - bovine
Length = 369
Score = 62.3 bits (150), Expect = 3e-09
Identities = 23/134 (17%), Positives = 49/134 (36%), Gaps = 13/134 (9%)
Query: 7 PRAACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLW 66
P + +TF +A + C + GG L +PR+ E + + L A ++ +
Sbjct: 249 PNGRSVGEKIFKTVGSEKTFQDAQQICTQAGGQLPSPRSGAENEALTQLATA--QNKAAF 306
Query: 67 IGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLE 126
+ + ++ P + ++NWA ++ CV + +W +
Sbjct: 307 LSMSDTRKEGTFIYPT--------GEPLVYSNWAPQEPNNDGGSENCVEIFP--NGKWND 356
Query: 127 GSCTLAVDGYLCQF 140
C +C+F
Sbjct: 357 KVCGEQ-RLVICEF 369
>sp|P35246|PSPD_BOVIN PULMONARY SURFACTANT-ASSOCIATED PROTEIN D PRECURSOR (SP-D) (PSP-D)
emb|CAA53510.1| (X75911) lung surfactant protein D [Bos taurus]
Length = 369
Score = 61.9 bits (149), Expect = 4e-09
Identities = 23/134 (17%), Positives = 49/134 (36%), Gaps = 13/134 (9%)
Query: 7 PRAACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLW 66
P + +TF +A + C + GG L +PR+ E + + L A ++ +
Sbjct: 249 PNGRSVGEKIFKTVGSEKTFQDAQQICTQAGGQLPSPRSGAENEALTQLATA--QNKAAF 306
Query: 67 IGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLE 126
+ + ++ P + ++NWA ++ CV + +W +
Sbjct: 307 LSMSDTRKEGTFIYPT--------GEPLVYSNWAPQEPNNDGGSENCVEIFP--NGKWND 356
Query: 127 GSCTLAVDGYLCQF 140
C +C+F
Sbjct: 357 KVCGEQ-RLVICEF 369
>ref|XP_008939.1| Fc fragment of IgE, low affinity II, receptor for (CD23A) [Homo
sapiens]
Length = 167
Score = 60.3 bits (145), Expect = 1e-08
Identities = 32/138 (23%), Positives = 51/138 (36%), Gaps = 18/138 (13%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQ 75
CY + ++ A AC ++ G L + +PEE + + WIGL+
Sbjct: 20 CYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQD----FLTKHASHTGSWIGLR----- 70
Query: 76 CQLQRPLRG-FTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVD 134
L+G F W G + +NWA + CV + SG RW + C +
Sbjct: 71 ---NLDLKGEFIWVDGSHFCS-SNWAPGEPTSRSQGEDCVMMRGSG--RWNDAFCDRKLG 124
Query: 135 GYLCQFGFEGACPALQDE 152
++C C E
Sbjct: 125 AWVCD--RLATCTPPASE 140
>gb|AAC25581.1| (AC005254) PGCN_HUMAN, PARTIAL CDS; 245 KD EARLY POSTNATAL CORE
GLYCOPROTEIN [Homo sapiens]
Length = 315
Score = 60.3 bits (145), Expect = 1e-08
Identities = 35/138 (25%), Positives = 52/138 (37%), Gaps = 15/138 (10%)
Query: 16 CYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQ 75
CY F RR + +A + CR G L + +PEE ++ WIGL + +
Sbjct: 93 CYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFIN-----SFGHENTWIGLNDRIVE 147
Query: 76 CQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCP-AQRCVALEASGEHRWLEGSCTLAVD 134
R F WT + F NW + + CV + A RW + C +
Sbjct: 148 -------RDFQWTD-NTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPCNYNLP 199
Query: 135 GYLCQFGFEGACPALQDE 152
Y+C+ G P E
Sbjct: 200 -YVCKKGTVLCGPPPAVE 216
CPU time: 27.23 user secs. 1.50 sys. secs 28.73 total secs.
Database: nr
Posted date: Dec 17, 2000 4:44 PM
Number of letters in database: 188,543,631
Number of sequences in database: 596,480
Lambda K H
0.308 0.164 0.528
Gapped
Lambda K H
0.270 0.0574 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65985537
Number of Sequences: 596480
Number of extensions: 2399974
Number of successful extensions: 6545
Number of sequences better than 10.0: 689
Number of HSP's better than 10.0 without gapping: 300
Number of HSP's successfully gapped in prelim test: 389
Number of HSP's that attempted gapping in prelim test: 5634
Number of HSP's gapped (non-prelim): 914
length of query: 157
length of database: 188,543,631
effective HSP length: 46
effective length of query: 111
effective length of database: 161,105,551
effective search space: 17882716161
effective search space used: 17882716161
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (20.8 bits)
S2: 69 (31.0 bits)