Score E
Sequences producing significant alignments: (bits) Value
gb|AAG33700.1| (AF225896) tensin [Homo sapiens] 3179 0.0
gb|AAG33701.1| (AF225897) tensin [Bos taurus] 2902 0.0
pir||A54970 tensin, cardiac muscle - chicken 1978 0.0
sp|Q04205|TENS_CHICK TENSIN >gi|619577|gb|AAA59053.1| (M966... 1977 0.0
pir||A57075 tensin - chicken (fragment) >gi|63805|emb|CAA79... 1969 0.0
pir||S27939 tensin - chicken >gi|212752|gb|AAA49087.1| (M74... 1963 0.0
ref|XP_002286.1| hypothetical protein FLJ10923 [Homo sapiens] 779 0.0
ref|NP_060744.1| hypothetical protein FLJ10923 [Homo sapien... 626 e-178
pir||T17293 hypothetical protein DKFZp434G162.1 - human (fr... 550 e-155
emb|CAA46992.1| (X66286) tensin [Gallus gallus] 507 e-142
dbj|BAB15041.1| (AK024948) unnamed protein product [Homo sa... 482 e-134
dbj|BAA83027.1| (AB028998) KIAA1075 protein [Homo sapiens] 480 e-134
pir||T46500 hypothetical protein DKFZp434D098.1 - human (fr... 388 e-106
dbj|BAB14682.1| (AK023794) unnamed protein product [Homo sa... 383 e-105
pir||T29328 hypothetical protein M01E11.7b - Caenorhabditis... 307 9e-82
pir||T29327 hypothetical protein M01E11.7a - Caenorhabditis... 307 9e-82
gb|AAF54393.1| (AE003683) CG9379 gene product [Drosophila m... 263 2e-68
gb|AAB23490.1| insertin=tensin homolog [chickens, gizzard, ... 233 1e-59
gb|AAA67648.1| (U26310) tensin [Rattus norvegicus] 214 6e-54
sp|P91301|YLPK_CAEEL HYPOTHETICAL 30.3 KD PROTEIN F46F11.3 ... 166 2e-39
pdb|1D5R|A Chain A, Crystal Structure Of The Pten Tumor Sup... 146 1e-33
ref|NP_005246.1| cyclin G associated kinase [Homo sapiens] ... 146 2e-33
ref|XP_003450.1| cyclin G associated kinase [Homo sapiens] 145 3e-33
sp|P97874|GAK_RAT CYCLIN G-ASSOCIATED KINASE >gi|7513955|pi... 145 3e-33
gb|AAB96620.1| (AF017185) protein tyrosine phosphatase and ... 144 1e-32
ref|NP_032986.1| phosphatase and tensin homolog [Mus muscul... 143 1e-32
ref|NP_000305.1| phosphatase and tensin homolog (mutated in... 143 1e-32
gb|AAD46165.1|AF144732_1 (AF144732) protein/lipid phosphata... 143 2e-32
gb|AAF23236.1|AF201905_1 (AF201905) phosphatase and tensin ... 138 4e-31
gb|AAF08382.1|AF144232_1 (AF144232) phosphatase PTEN [Droso... 138 4e-31
gb|AAD45364.1|AF161259_1 (AF161259) PTEN3 [Drosophila melan... 138 4e-31
gb|AAD45363.1|AF161258_1 (AF161258) PTEN2 [Drosophila melan... 138 4e-31
gb|AAD45362.1|AF161257_1 (AF161257) PTEN1 [Drosophila melan... 138 4e-31
gb|AAC52017.1| (AF019083) phosphatase and tensin homolog 2 ... 138 5e-31
gb|AAB70558.1| (AF017999) putative protein tyrosine phospha... 136 2e-30
emb|CAB90528.1| (AL163201) tensin, putative protein-tyrosin... 124 7e-27
sp|Q27974|AUXI_BOVIN AUXILIN >gi|2136718|pir||S68983 auxili... 122 3e-26
ref|NP_037447.1| transmembrane phosphatase with tensin homo... 122 5e-26
ref|NP_055602.1| KIAA0473 gene product [Homo sapiens] >gi|3... 120 1e-25
ref|XP_005775.1| similar to transmembrane phosphatase with ... 118 5e-25
emb|CAA10315.1| (AJ131181) DAF-18 protein [Caenorhabditis e... 114 1e-23
pir||T32574 hypothetical protein T07A9.6 - Caenorhabditis e... 114 1e-23
dbj|BAB11013.1| (AB009054) contains similarity to protein-t... 113 2e-23
dbj|BAA99691.1| (AB025624) tyrosine phosphatase-like [Arabi... 106 2e-21
pir||T45864 probable tyrosine phosphatase - Arabidopsis tha... 101 6e-20
gb|AAF23237.1|AF201906_1 (AF201906) phosphatase and tensin ... 94 1e-17
gb|AAF52168.1| (AE003607) CG1107 gene product [alt 1] [Dros... 79 5e-13
gb|AAF50718.1| (AE003564) CG6062 gene product [Drosophila m... 76 2e-12
dbj|BAB11454.1| (AB010070) gb|AAD23008.1~gene_id:MBK20.21~s... 74 2e-11
gb|AAF50725.1| (AE003564) CG13289 gene product [Drosophila ... 73 2e-11
>gb|AAG33700.1| (AF225896) tensin [Homo sapiens]
Length = 1735
Score = 3179 bits (8150), Expect = 0.0
Identities = 1571/1735 (90%), Positives = 1571/1735 (90%)
Query: 1 MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL 60
MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL
Sbjct: 1 MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL 60
Query: 61 SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRI 120
SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRI
Sbjct: 61 SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRI 120
Query: 121 GVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKIN 180
GVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKIN
Sbjct: 121 GVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKIN 180
Query: 181 NKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL 240
NKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL
Sbjct: 181 NKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL 240
Query: 241 LLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV 300
LLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV
Sbjct: 241 LLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV 300
Query: 301 EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGP 360
EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGP
Sbjct: 301 EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGP 360
Query: 361 LDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDE 420
LDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDE
Sbjct: 361 LDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDE 420
Query: 421 PVPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHV 480
PVPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHV
Sbjct: 421 PVPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHV 480
Query: 481 VPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPL 540
VPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPL
Sbjct: 481 VPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPL 540
Query: 541 TNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAW 600
TNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAW
Sbjct: 541 TNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAW 600
Query: 601 PQPVTTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWXXXXXXXXXX 660
PQPVTTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSW
Sbjct: 601 PQPVTTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQP 660
Query: 661 XXXXXXXERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLE 720
ERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLE
Sbjct: 661 RPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLE 720
Query: 721 PASAAAPLHKSQSVPGAWPGAXXXXXXXXXXXXXXXHPLTQSRSGYIPSGHSLGTPEPAP 780
PASAAAPLHKSQSVPGAWPGA HPLTQSRSGYIPSGHSLGTPEPAP
Sbjct: 721 PASAAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTPEPAP 780
Query: 781 RASLESVPPGRSYSPYDYQPCLAGPNQDFHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 840
RASLESVPPGRSYSPYDYQPCLAGPNQDFH
Sbjct: 781 RASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLP 840
Query: 841 XXTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQXXXXXXXXXXXXXSD 900
TAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQ SD
Sbjct: 841 GLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASD 900
Query: 901 GQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTX 960
GQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGT
Sbjct: 901 GQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTS 960
Query: 961 XXXXXXXXXXXXXGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSE 1020
GLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSE
Sbjct: 961 PSSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSE 1020
Query: 1021 EPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVXXXXXXXXX 1080
EPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFV
Sbjct: 1021 EPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSS 1080
Query: 1081 XXXXADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTV 1140
ADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTV
Sbjct: 1081 PILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTV 1140
Query: 1141 GSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGRRXX 1200
GSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGRR
Sbjct: 1141 GSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGRRAI 1200
Query: 1201 XXXXXXXXXXXXXHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLH 1260
HHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLH
Sbjct: 1201 NPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLH 1260
Query: 1261 NKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLXXXXXXXXXXXCLDRH 1320
NKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHL CLDRH
Sbjct: 1261 NKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRH 1320
Query: 1321 VAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLXXXXXXXXXXXXXFRQG 1380
VAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGL FRQG
Sbjct: 1321 VAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQG 1380
Query: 1381 SPTPALPEKRRMSVGDRAGSLPNYATINGKXXXXXXXXXXXXXXXXXXXXXHTLPDFSKY 1440
SPTPALPEKRRMSVGDRAGSLPNYATINGK HTLPDFSKY
Sbjct: 1381 SPTPALPEKRRMSVGDRAGSLPNYATINGKVASPVPSGMSSPSGGSTVSFSHTLPDFSKY 1440
Query: 1441 SMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLA 1500
SMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLA
Sbjct: 1441 SMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLA 1500
Query: 1501 MKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSII 1560
MKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSII
Sbjct: 1501 MKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSII 1560
Query: 1561 PLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAACNVLFINSVDMESLTGPQAISK 1620
PLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAACNVLFINSVDMESLTGPQAISK
Sbjct: 1561 PLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAACNVLFINSVDMESLTGPQAISK 1620
Query: 1621 ATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMK 1680
ATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMK
Sbjct: 1621 ATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMK 1680
Query: 1681 TEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR 1735
TEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR
Sbjct: 1681 TEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR 1735
>gb|AAG33701.1| (AF225897) tensin [Bos taurus]
Length = 1715
Score = 2902 bits (7440), Expect = 0.0
Identities = 1443/1739 (82%), Positives = 1468/1739 (83%), Gaps = 28/1739 (1%)
Query: 1 MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL 60
MS SRT EDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL
Sbjct: 1 MSTSRTTEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL 60
Query: 61 SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRI 120
SERRPDITKLHAKVLEFGWPDLHTPALEKICS+CKAMDTWLNADPHNVVVLHNKGNRGRI
Sbjct: 61 SERRPDITKLHAKVLEFGWPDLHTPALEKICSVCKAMDTWLNADPHNVVVLHNKGNRGRI 120
Query: 121 GVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKIN 180
GVVIAAYMHYSNISASAD ALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIK+N
Sbjct: 121 GVVIAAYMHYSNISASADHALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMN 180
Query: 181 NKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL 240
NKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYN+ GDSQTS+CITIEPGL
Sbjct: 181 NKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNVQGDSQTSICITIEPGL 240
Query: 241 LLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV 300
LLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV
Sbjct: 241 LLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV 300
Query: 301 EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGP 360
EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRW SYDNF+GHRDDGMEEVVGHT G
Sbjct: 301 EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWHSYDNFNGHRDDGMEEVVGHTPGT 360
Query: 361 LDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDE 420
LDGSLYAKVKKKDSLHGS GAVNATRP LSATPNHVEHTLSVSSDSGNSTASTKTDKTDE
Sbjct: 361 LDGSLYAKVKKKDSLHGSNGAVNATRPVLSATPNHVEHTLSVSSDSGNSTASTKTDKTDE 420
Query: 421 PVPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHV 480
P PG +SA AALSP+EKRELDRLLSGFGLEREKQGAMYH QHLRSRP GG A PSSGRH+
Sbjct: 421 PAPGPASAPAALSPEEKRELDRLLSGFGLEREKQGAMYHPQHLRSRPVGGPAAPSSGRHI 480
Query: 481 VPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPL 540
VPAQVHV GG L+ ERETDILDDELPNQDGHS GSMGTLSSLDGVTNTSEGGYPEALSPL
Sbjct: 481 VPAQVHVRGGVLSVERETDILDDELPNQDGHSVGSMGTLSSLDGVTNTSEGGYPEALSPL 540
Query: 541 TNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAW 600
TNGLDK YPMEPMVNGGGYPYESASRA A AGHTAPMRPSYS QEGLAGYQREGPHPAW
Sbjct: 541 TNGLDKPYPMEPMVNGGGYPYESASRAVSAQAGHTAPMRPSYSTQEGLAGYQREGPHPAW 600
Query: 601 PQPVTTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWXXXXXXXXXX 660
PQ TTSHY HDP+GMFRSQSF E EPQLPPAP RGGSSREAVQRGLNSW
Sbjct: 601 PQSATTSHYGHDPNGMFRSQSFPETEPQLPPAPARGGSSREAVQRGLNSWQQQQQQQQQQ 660
Query: 661 XXXX---XXXERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLML 717
ER HLESL SRPSPQPLAE P+ LPEFPRAASQQEIEQSIE LNMLML
Sbjct: 661 QQPRPPPRQQERVHLESLGLSRPSPQPLAEPPMSGLPEFPRAASQQEIEQSIEALNMLML 720
Query: 718 DLEPASAAAPLHKSQSVPGAWPGAXXXXXXXXXXXXXXXHPLTQSRSGYIPSGHSLGTPE 777
DLEPA+A APLHKSQSVPGAWPGA HPLTQSRSGYIPSGHSLGTPE
Sbjct: 721 DLEPATAGAPLHKSQSVPGAWPGASPLSSQPFSGSSCQSHPLTQSRSGYIPSGHSLGTPE 780
Query: 778 PAPRASLESVPPGRSYSPYDYQPCLAGPNQDFHXXXXXXXXXXXXXXXXXXXXXXXXXXX 837
PAPRA LESVP GR YSPYDYQPC GPNQ +H
Sbjct: 781 PAPRAPLESVPTGRPYSPYDYQPCPTGPNQSYHPKSPATSSSSSFLPTTQSSVGPQQPPA 840
Query: 838 XXXXXTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQXXXXXXXXXXXX 897
T QP L PKE TSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQ
Sbjct: 841 SLPGLTTQPQLPPKEVTSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRKRA 900
Query: 898 XSDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEME 957
SDGQYENQSPE TSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEME
Sbjct: 901 ASDGQYENQSPEPTSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEME 960
Query: 958 GTXXXXXXXXXXXXXXGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVR 1017
GT GLAKTPLSALGLKPHNPADILLHPTG
Sbjct: 961 GTSPTSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTG------------------ 1002
Query: 1018 LSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVXXXXXX 1077
EPRSYVESV RTAVAGPR Q+ EPKSFSAPA QAYGHE PLR GTLGGSFV
Sbjct: 1003 ---EPRSYVESVVRTAVAGPRTQEPEPKSFSAPAAQAYGHETPLRIGTLGGSFVSPSPLS 1059
Query: 1078 XXXXXXXADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPL 1137
ADSTSVGSFPSGESSDQG RTPTQPLL+SGFRSGSLGQPSP AQRNYQSSSPL
Sbjct: 1060 TSSPILSADSTSVGSFPSGESSDQGARTPTQPLLDSGFRSGSLGQPSPLAQRNYQSSSPL 1119
Query: 1138 PTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGR 1197
PT GSSYSSPDYSLQ F SSPE QAR+QFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGR
Sbjct: 1120 PTAGSSYSSPDYSLQQF-SSPEGQARSQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGR 1178
Query: 1198 RXXXXXXXXXXXXXXXHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVS 1257
R H Q+MGP GTGFHG+T SSPQSSAATTPGSPSL RHP QVS
Sbjct: 1179 RAVNPSLAAPSSPSLSHRQVMGPLGTGFHGNTGSSPQSSAATTPGSPSLGRHPGA--QVS 1236
Query: 1258 GLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLXXXXXXXXXXXCL 1317
LH V T PGSPSLGRHPGAHQG LAS LHSNA+ASPGSPSLGRHL L
Sbjct: 1237 NLHGNVVTRPGSPSLGRHPGAHQGTLASNLHSNAVASPGSPSLGRHLGGSGSVVPGSPSL 1296
Query: 1318 DRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLXXXXXXXXXXXXXF 1377
DRHV YGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGL F
Sbjct: 1297 DRHVPYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAF 1356
Query: 1378 RQGSPTPALPEKRRMSVGDRAGSLPNYATINGKXXXX-XXXXXXXXXXXXXXXXXHTLPD 1436
RQGSPTPALPEKRRMS+GDRAGSLPNYAT+NGK HTLPD
Sbjct: 1357 RQGSPTPALPEKRRMSMGDRAGSLPNYATVNGKVSSSPVASGMSSPSGGSTVSFSHTLPD 1416
Query: 1437 FSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGA 1496
FSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGA
Sbjct: 1417 FSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGA 1476
Query: 1497 YGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQ 1556
YGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQ
Sbjct: 1477 YGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQ 1536
Query: 1557 HSIIPLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAACNVLFINSVDMESLTGPQ 1616
HSIIPLALPCKLVIPNRDPTDESKDSSGPANST+DLLKQGAACNVLF+NSVDMESLTGPQ
Sbjct: 1537 HSIIPLALPCKLVIPNRDPTDESKDSSGPANSTSDLLKQGAACNVLFVNSVDMESLTGPQ 1596
Query: 1617 AISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQER 1676
AISKA SETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQER
Sbjct: 1597 AISKAISETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQER 1656
Query: 1677 KWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR 1735
KW KTEGGAPAKLFGFVARKQGS TDNACHLFAELDPNQPASAIV+FVSKVML+AGQKR
Sbjct: 1657 KWTKTEGGAPAKLFGFVARKQGSATDNACHLFAELDPNQPASAIVSFVSKVMLSAGQKR 1715
>pir||A54970 tensin, cardiac muscle - chicken
Length = 1744
Score = 1978 bits (5067), Expect = 0.0
Identities = 1094/1816 (60%), Positives = 1208/1816 (66%), Gaps = 207/1816 (11%)
Query: 1 MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL 60
MSV+ ME SCELDLVY+TERIIAVS+PSTA E++FRSNLREVA MLKSKHG NY+LFNL
Sbjct: 55 MSVTAAMESSCELDLVYITERIIAVSYPSTAEEQSFRSNLREVAHMLKSKHGDNYVLFNL 114
Query: 61 SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRI 120
SERR DI+KLH KVL+FGWPDLHTPALEKICSICKAMDTWLNA HNVVVLHNKGNRGR+
Sbjct: 115 SERRHDISKLHPKVLDFGWPDLHTPALEKICSICKAMDTWLNAAAHNVVVLHNKGNRGRL 174
Query: 121 GVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKIN 180
GVV+AAYMHYSNISASADQALDRFAMKRFYEDK+VP+GQPSQ+RY+HYFSGLLSGSIK+N
Sbjct: 175 GVVVAAYMHYSNISASADQALDRFAMKRFYEDKVVPVGQPSQKRYIHYFSGLLSGSIKMN 234
Query: 181 NKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL 240
NKPLFLHHVIMHGIPNFESKGGCRPFL+IYQAMQPVYTSGIYN+ GDSQT +CITIEPGL
Sbjct: 235 NKPLFLHHVIMHGIPNFESKGGCRPFLKIYQAMQPVYTSGIYNVQGDSQTGICITIEPGL 294
Query: 241 LLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV 300
LLKGDILLKCYHKKFRSP RDVIFRVQFHTCA+HDL +VFGKEDLD+AF+D+RFPEYGKV
Sbjct: 295 LLKGDILLKCYHKKFRSPTRDVIFRVQFHTCAVHDLDIVFGKEDLDEAFRDERFPEYGKV 354
Query: 301 EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDG----------- 349
+FVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSY+NF+ R+D
Sbjct: 355 KFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYENFNIQREDSAEGTWAEPALP 414
Query: 350 ---MEEVVGHTQGPLDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDS 406
+E+ VGHTQGPLDGSLYAKVKKKDSLHGS GAVN R LSA PNHVEHTLSVSSDS
Sbjct: 415 GKHLEKEVGHTQGPLDGSLYAKVKKKDSLHGSIGAVNTARLPLSAAPNHVEHTLSVSSDS 474
Query: 407 GNSTASTKTDKTDEP-VPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRS 465
GNSTASTKTD+TDEP PGA + A LSP+EKRELDRLL GFGLE A H
Sbjct: 475 GNSTASTKTDRTDEPGAPGAPTGHAVLSPEEKRELDRLLVGFGLE---SAAPMHNHAPGP 531
Query: 466 RPAGGSAVPSSGRHVVPAQVHVNGGA--LASERETDILDDELPNQDGHSAGSMGTLSSLD 523
PA A P GRHVVPAQVHVNG L +ERETDILDDELPNQDGHS GS+GTLSSLD
Sbjct: 532 APARLPAGP--GRHVVPAQVHVNGAGTPLLAERETDILDDELPNQDGHSVGSLGTLSSLD 589
Query: 524 GVTNTSEGGYPEA-----LSPLTNG-----------LDKSYPMEPMVNGGGYPYESASRA 567
G T SE G+ EA LS L NG + Y EP+ N G YPY + +
Sbjct: 590 GTTTASEAGFHEAPRVGSLSSLPNGPASYNGAEKMLKEGLYEAEPLSN-GAYPYSNQNTL 648
Query: 568 GPAH-AGHTAPMRPSYSAQEGLAGYQREGP---HPAWPQPVTTSH--YAHDPSGMFRSQS 621
H A +RPS SAQE LAGY + P PAW QP Y +D RSQS
Sbjct: 649 MGHHLRDPLAHLRPSRSAQEHLAGYPQRQPASASPAWLQPPVPQPYLYGYDLPSAHRSQS 708
Query: 622 FS-------EAEPQLPPAPVRGGSSREAVQRGLNSWXXXXXXXXXXXXXXXXXERAHLES 674
F EA LP AP R SSREAVQRGLNSW E +H S
Sbjct: 709 FPAVRTAKYEANLALPQAPARSTSSREAVQRGLNSWQQRGGSRPPSQLHDGGLE-SHSPS 767
Query: 675 LVASRPSPQPLAETP--IPSLPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQ 732
L + P P PL P S+PEFPRA S++EIEQSIE L++LMLDL P+ +HKSQ
Sbjct: 768 LSSCSPQPSPLQPMPPHSHSMPEFPRAPSRREIEQSIEALDVLMLDLAPS-----VHKSQ 822
Query: 733 SVPGA-----WPGAXXXXXXXXXXXXXXXHP---LTQSRSGYIPSGHSLGT--------P 776
SVP A P A P + Q RS G S+GT P
Sbjct: 823 SVPSAATRQDKPAAMLSSLSAQALSGHYAQPTPQVVQPRS----FGTSVGTDPLAKAYSP 878
Query: 777 EPAPRASLESVPPG-------RSYSPYDYQPCLAGPNQDFHXXXXXXXXXXXXXXXXXXX 829
P A+ + P +Y+PY YQP P +
Sbjct: 879 GPLVPAARSTAEPDYTVHEYRETYTPYSYQPV---PEPRSYGSAPASILPLSASYSPAGS 935
Query: 830 XXXXXXXXXXXXXTAQPLLSPK--EATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQXX 887
AQ L K E+ D SR+ EEPLNLEGLVAHRVAGVQ+REK
Sbjct: 936 QQLLVSSPPSPTAPAQSQLPHKGLESYEDLSRS-GEEPLNLEGLVAHRVAGVQSREKSPE 994
Query: 888 XXXXXXXXXXXSDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLH 947
SD YE SPE SPRSP V +SPE+ TIA NPGGRPKEPHLH
Sbjct: 995 ESTVPARRRTPSDSHYEKSSPEPGSPRSPTV------LSPEVVSTIAANPGGRPKEPHLH 1048
Query: 948 SYKEAFEEMEGTXXXXXXXXXXXXXXGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQP 1007
SYKEAFEEME GLAKTPLSALGLKPHNPADILLHP G
Sbjct: 1049 SYKEAFEEMESASPSSLTSGGVRSPPGLAKTPLSALGLKPHNPADILLHPVG-------- 1100
Query: 1008 EEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLG 1067
E EG+ EEPRSYVESVARTA G ++ + PA Q G E+P RNG G
Sbjct: 1101 -ELEGEAGADSEEEPRSYVESVARTATTG--------RAGNLPAAQPVGLEVPARNGAFG 1151
Query: 1068 GSFVXXXXXXXXXXXXXADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSA 1127
SF D S+ S+PS E S G TP + E+ +RS + Q +PSA
Sbjct: 1152 NSFTVPSPVSTSSPIHSVDGASLRSYPS-EGSPHGTVTPPHAVAETAYRSPMVSQ-TPSA 1209
Query: 1128 QRNYQSSSP----LPTVGSSYSSPDY--SLQHFSSSPESQARAQFSVAGVHTVPGSPQAR 1181
+YQ+SSP T+GS Y+SPDY F P+++ + Q SV GVH +PGSP+
Sbjct: 1210 HSSYQTSSPSSFQAGTLGSPYASPDYPDGRGGFQPDPQARQQPQVSVVGVHALPGSPRTL 1269
Query: 1182 HRTVGTNTPPSPGFGRRXXXXXXXXXXXXXXXHHQMMGPPGTGFHGSTVSSPQSSAATTP 1241
HRTV TNTPPSPGFGRR + + A+ P
Sbjct: 1270 HRTVATNTPPSPGFGRR---------------------------------AANPAVASVP 1296
Query: 1242 GSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLG 1301
GSP L RH + PGSPSL R H A PGSP
Sbjct: 1297 GSPGLGRHTVSPH----------APPGSPSLAR-------------HQMAAVPPGSPMY- 1332
Query: 1302 RHLXXXXXXXXXXXCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYP 1361
GYS+PE+RRPTLSRQSSASGYQ PSTPSFPVSPAYYP
Sbjct: 1333 -----------------------GYSSPEERRPTLSRQSSASGYQPPSTPSFPVSPAYYP 1369
Query: 1362 GLXXXXXXXXXXXXXFRQGSPT--PALPEKRRMSVGDRAGSLPNYATINGKXXXXXXXXX 1419
G +RQGSPT PALPEKRRMS G+R+ SLPNYAT+NGK
Sbjct: 1370 G-TSTPHSSSPDSAAYRQGSPTPQPALPEKRRMSAGERSNSLPNYATVNGKASSPLSSGM 1428
Query: 1420 XXXXXXXXXXXXHTLPDFSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKD 1479
HTLPDFSK+SMPD SPETRA VKFVQDTSKYWYKP+ISREQAIALLKD
Sbjct: 1429 SSPSSGSAVAFSHTLPDFSKFSMPDISPETRANVKFVQDTSKYWYKPDISREQAIALLKD 1488
Query: 1480 QEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLK 1539
+EPGAFIIRDSHSFRGAYGLAMKV+SPPPT+MQQNKKGD+T+ELVRHFLIET PRGVKLK
Sbjct: 1489 REPGAFIIRDSHSFRGAYGLAMKVASPPPTVMQQNKKGDITNELVRHFLIETSPRGVKLK 1548
Query: 1540 GCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAAC 1599
GCPNEPNFG LSALVYQHSI+PLALPCKLVIP+RDP +E KD++ NS DLLKQGAAC
Sbjct: 1549 GCPNEPNFGCLSALVYQHSIMPLALPCKLVIPDRDPMEEKKDAASTTNSATDLLKQGAAC 1608
Query: 1600 NVLFINSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRR 1659
NVLFINSV+MESLTGPQAISKA +ETL ADPTP ATIVHFKVSAQGITLTDNQRKLFFRR
Sbjct: 1609 NVLFINSVEMESLTGPQAISKAVAETLVADPTPTATIVHFKVSAQGITLTDNQRKLFFRR 1668
Query: 1660 HYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASA 1719
HYPLNTVTFCDLDPQERKW KT+G PAKLFGFVARKQGSTTDN CHLFAELDP+QPA+A
Sbjct: 1669 HYPLNTVTFCDLDPQERKWTKTDGSGPAKLFGFVARKQGSTTDNVCHLFAELDPDQPAAA 1728
Query: 1720 IVNFVSKVMLNAGQKR 1735
IVNFVS+VML +GQKR
Sbjct: 1729 IVNFVSRVMLGSGQKR 1744
>sp|Q04205|TENS_CHICK TENSIN
gb|AAA59053.1| (M96625) cardiac muscle tensin [Gallus gallus]
Length = 1744
Score = 1977 bits (5066), Expect = 0.0
Identities = 1095/1816 (60%), Positives = 1208/1816 (66%), Gaps = 207/1816 (11%)
Query: 1 MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL 60
MSV+ ME SCELDLVY+TERIIAVS+PSTA E++FRSNLREVA MLKSKHG NY+LFNL
Sbjct: 55 MSVTAAMESSCELDLVYITERIIAVSYPSTAEEQSFRSNLREVAHMLKSKHGDNYVLFNL 114
Query: 61 SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRI 120
SERR DI+KLH KVL+FGWPDLHTPALEKICSICKAMDTWLNA HNVVVLHNKGNRGR+
Sbjct: 115 SERRHDISKLHPKVLDFGWPDLHTPALEKICSICKAMDTWLNAAAHNVVVLHNKGNRGRL 174
Query: 121 GVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKIN 180
GVV+AAYMHYSNISASADQALDRFAMKRFYEDK+VP+GQPSQ+RY+HYFSGLLSGSIK+N
Sbjct: 175 GVVVAAYMHYSNISASADQALDRFAMKRFYEDKVVPVGQPSQKRYIHYFSGLLSGSIKMN 234
Query: 181 NKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL 240
NKPLFLHHVIMHGIPNFESKGGCRPFL+IYQAMQPVYTSGIYN+ GDSQT +CITIEPGL
Sbjct: 235 NKPLFLHHVIMHGIPNFESKGGCRPFLKIYQAMQPVYTSGIYNVQGDSQTGICITIEPGL 294
Query: 241 LLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV 300
LLKGDILLKCYHKKFRSP RDVIFRVQFHTCA+HDL +VFGKEDLD+AF+D+RFPEYGKV
Sbjct: 295 LLKGDILLKCYHKKFRSPTRDVIFRVQFHTCAVHDLDIVFGKEDLDEAFRDERFPEYGKV 354
Query: 301 EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDG----------- 349
EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSY+NF+ R+D
Sbjct: 355 EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYENFNIQREDSAEGTWAEPALP 414
Query: 350 ---MEEVVGHTQGPLDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDS 406
+E+ VGHTQGPLDGSLYAKVKKKDSLHGS GAVN R LSA PNHVEHTLSVSSDS
Sbjct: 415 GKHLEKEVGHTQGPLDGSLYAKVKKKDSLHGSIGAVNTARLPLSAAPNHVEHTLSVSSDS 474
Query: 407 GNSTASTKTDKTDEP-VPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRS 465
GNSTASTKTD+TDEP PGA + A LSP+EKR++DRLL GFGLE A H
Sbjct: 475 GNSTASTKTDRTDEPGAPGAPTGHAVLSPEEKRDVDRLLVGFGLE---SAAPMHNHAPGP 531
Query: 466 RPAGGSAVPSSGRHVVPAQVHVNGGA--LASERETDILDDELPNQDGHSAGSMGTLSSLD 523
PA A P GRHVVPAQVHVNG L +ERETDILDDELPNQDGHS GS+GTLSSLD
Sbjct: 532 APARLPAGP--GRHVVPAQVHVNGAGTPLLAERETDILDDELPNQDGHSVGSLGTLSSLD 589
Query: 524 GVTNTSEGGYPEA-----LSPLTNG-----------LDKSYPMEPMVNGGGYPYESASRA 567
G T SE G+ EA LS L NG + Y EP+ N G YPY + +
Sbjct: 590 GTTTASEAGFHEAPRVGSLSSLPNGPASYNGAEKMLKEGLYEAEPLSN-GAYPYSNQNTL 648
Query: 568 GPAH-AGHTAPMRPSYSAQEGLAGYQREGP---HPAWPQPVTTSH--YAHDPSGMFRSQS 621
H A +RPS SAQE LAGY + P PAW QP Y +D RSQS
Sbjct: 649 MGHHLRDPLAHLRPSRSAQEHLAGYPQRQPASASPAWLQPPVPQPYLYGYDLPSAHRSQS 708
Query: 622 FS-------EAEPQLPPAPVRGGSSREAVQRGLNSWXXXXXXXXXXXXXXXXXERAHLES 674
F EA LP AP R SSREAVQRGLNSW E +H S
Sbjct: 709 FPAVGTAKYEANLALPQAPARSTSSREAVQRGLNSWQQQGGSRPPSQLHDGGLE-SHSPS 767
Query: 675 LVASRPSPQPLAETP--IPSLPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQ 732
L + P P PL P S+PEFPRA S++EIEQSIE L++LMLDL P+ +HKSQ
Sbjct: 768 LSSCSPQPSPLQPMPPHSHSMPEFPRAPSRREIEQSIEALDVLMLDLAPS-----VHKSQ 822
Query: 733 SVPGA-----WPGAXXXXXXXXXXXXXXXHP---LTQSRSGYIPSGHSLGT-PEPAPRAS 783
SVP A P A P + Q RS G S+GT P P +
Sbjct: 823 SVPSAATRQDKPAAMLSSLSAQRLSGHYAQPTPQVVQPRS----FGTSVGTDPLAKPYSP 878
Query: 784 LESVPPGRS--------------YSPYDYQPCLAGPNQDFHXXXXXXXXXXXXXXXXXXX 829
VP RS Y+PY YQP P +
Sbjct: 879 GPLVPAARSTAEPDYTVHEYRETYTPYSYQPV---PEPRSYGSAPASILPLSASYSPAGS 935
Query: 830 XXXXXXXXXXXXXTAQPLLSPK--EATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQXX 887
AQ L K E+ D SR+ EEPLNLEGLVAHRVAGVQ+REK
Sbjct: 936 QQLLVSSPPSPTAPAQSQLPHKGLESYEDLSRS-GEEPLNLEGLVAHRVAGVQSREKSPE 994
Query: 888 XXXXXXXXXXXSDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLH 947
SD YE SPE SPRSP V +SPE+ TIA NPGGRPKEPHLH
Sbjct: 995 ESTVPARRRTPSDSHYEKSSPEPGSPRSPTV------LSPEVVSTIAANPGGRPKEPHLH 1048
Query: 948 SYKEAFEEMEGTXXXXXXXXXXXXXXGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQP 1007
SYKEAFEEME GLAKTPLSALGLKPHNPADILLHP G
Sbjct: 1049 SYKEAFEEMESASPSSLTSGGVRSPPGLAKTPLSALGLKPHNPADILLHPVG-------- 1100
Query: 1008 EEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLG 1067
E EG+ EEPRSYVESVARTA G ++ + PA Q G E+P RNG G
Sbjct: 1101 -ELEGEAGADSEEEPRSYVESVARTATTG--------RAGNLPAAQPVGLEVPARNGAFG 1151
Query: 1068 GSFVXXXXXXXXXXXXXADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSA 1127
SF D S+ S+PS E S G TP + E+ +RS + Q +PSA
Sbjct: 1152 NSFTVPSPVSTSSPIHSVDGASLRSYPS-EGSPHGTVTPPHAVAETAYRSPMVSQ-TPSA 1209
Query: 1128 QRNYQSSSP----LPTVGSSYSSPDY--SLQHFSSSPESQARAQFSVAGVHTVPGSPQAR 1181
+YQ+SSP T+GS Y+SPDY F P+++ + Q SV GVH +PGSP+
Sbjct: 1210 HSSYQTSSPSSFQAGTLGSPYASPDYPDGRGGFQPDPQARQQPQVSVVGVHALPGSPRTL 1269
Query: 1182 HRTVGTNTPPSPGFGRRXXXXXXXXXXXXXXXHHQMMGPPGTGFHGSTVSSPQSSAATTP 1241
HRTV TNTPPSPGFGRR + + A+ P
Sbjct: 1270 HRTVATNTPPSPGFGRR---------------------------------AANPAVASVP 1296
Query: 1242 GSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLG 1301
GSP L RH + PGSPSL R H A PGSP
Sbjct: 1297 GSPGLGRHTVSPH----------APPGSPSLAR-------------HQMAAVPPGSPMY- 1332
Query: 1302 RHLXXXXXXXXXXXCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYP 1361
GYS+PE+RRPTLSRQSSASGYQ PSTPSFPVSPAYYP
Sbjct: 1333 -----------------------GYSSPEERRPTLSRQSSASGYQPPSTPSFPVSPAYYP 1369
Query: 1362 GLXXXXXXXXXXXXXFRQGSPT--PALPEKRRMSVGDRAGSLPNYATINGKXXXXXXXXX 1419
G +RQGSPT PALPEKRRMS G+R+ SLPNYAT+NGK
Sbjct: 1370 G-TSTPHSSSPDSAAYRQGSPTPQPALPEKRRMSAGERSNSLPNYATVNGKASSPLSSGM 1428
Query: 1420 XXXXXXXXXXXXHTLPDFSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKD 1479
HTLPDFSK+SMPD SPETRA VKFVQDTSKYWYKP+ISREQAIALLKD
Sbjct: 1429 SSPSSGSAVAFSHTLPDFSKFSMPDISPETRANVKFVQDTSKYWYKPDISREQAIALLKD 1488
Query: 1480 QEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLK 1539
+EPGAFIIRDSHSFRGAYGLAMKV+SPPPT+MQQNKKGD+T+ELVRHFLIET PRGVKLK
Sbjct: 1489 REPGAFIIRDSHSFRGAYGLAMKVASPPPTVMQQNKKGDITNELVRHFLIETSPRGVKLK 1548
Query: 1540 GCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAAC 1599
GCPNEPNFG LSALVYQHSI+PLALPCKLVIP+RDP +E KD++ NS DLLKQGAAC
Sbjct: 1549 GCPNEPNFGCLSALVYQHSIMPLALPCKLVIPDRDPMEEKKDAASTTNSATDLLKQGAAC 1608
Query: 1600 NVLFINSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRR 1659
NVLFINSV+MESLTGPQAISKA +ETL ADPTP ATIVHFKVSAQGITLTDNQRKLFFRR
Sbjct: 1609 NVLFINSVEMESLTGPQAISKAVAETLVADPTPTATIVHFKVSAQGITLTDNQRKLFFRR 1668
Query: 1660 HYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASA 1719
HYPLNTVTFCDLDPQERKW KT+G PAKLFGFVARKQGSTTDN CHLFAELDP+QPA+A
Sbjct: 1669 HYPLNTVTFCDLDPQERKWTKTDGSGPAKLFGFVARKQGSTTDNVCHLFAELDPDQPAAA 1728
Query: 1720 IVNFVSKVMLNAGQKR 1735
IVNFVS+VML +GQKR
Sbjct: 1729 IVNFVSRVMLGSGQKR 1744
>pir||A57075 tensin - chicken (fragment)
emb|CAA79215.1| (Z18529) tensin [Gallus gallus]
gb|AAA73949.1| (L06662) tensin [Gallus gallus]
Length = 1792
Score = 1969 bits (5045), Expect = 0.0
Identities = 1090/1816 (60%), Positives = 1205/1816 (66%), Gaps = 207/1816 (11%)
Query: 1 MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL 60
MSV+ E SCELDLVY+TERIIAVS+PSTA E++FRSNLREVA MLKSKHG NY+LFNL
Sbjct: 103 MSVTAATESSCELDLVYITERIIAVSYPSTAEEQSFRSNLREVAHMLKSKHGDNYVLFNL 162
Query: 61 SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRI 120
SERR DI+KLH KVL+FGWPDLHTPALEKICSICKAMDTWLNA HNVVVLHNKGNRGR+
Sbjct: 163 SERRHDISKLHPKVLDFGWPDLHTPALEKICSICKAMDTWLNAAAHNVVVLHNKGNRGRL 222
Query: 121 GVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKIN 180
GVV+AAYMHYSNISASADQALDRFAMKRFYEDK+VP+GQPSQ+RY+HYFSGLLSGSIK+N
Sbjct: 223 GVVVAAYMHYSNISASADQALDRFAMKRFYEDKVVPVGQPSQKRYIHYFSGLLSGSIKMN 282
Query: 181 NKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL 240
NKPLFLHHVIMHGIPNFESKGGCRPFL+IYQAMQPVYTSGIYN+ GDSQT +CITIEPGL
Sbjct: 283 NKPLFLHHVIMHGIPNFESKGGCRPFLKIYQAMQPVYTSGIYNVQGDSQTGICITIEPGL 342
Query: 241 LLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV 300
LLKGDILLKCYHKKFRSP RDVIFRVQFHTCA+HDL +VFGKEDLD+AF+D+RFPEYGKV
Sbjct: 343 LLKGDILLKCYHKKFRSPTRDVIFRVQFHTCAVHDLDIVFGKEDLDEAFRDERFPEYGKV 402
Query: 301 EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDG----------- 349
EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSY+NF+ R+D
Sbjct: 403 EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYENFNIQREDSTEGTWAEPALP 462
Query: 350 ---MEEVVGHTQGPLDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDS 406
+E+ VGHTQGPLDGSLYAKVKKKDSLHGS GAVNA R LSA PNHVEHTLSVSSDS
Sbjct: 463 GKHLEKEVGHTQGPLDGSLYAKVKKKDSLHGSIGAVNAARLPLSAAPNHVEHTLSVSSDS 522
Query: 407 GNSTASTKTDKTDEP-VPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRS 465
GNSTASTKTD+TDEP PGA + A LSP+EKRELDRLL GFGLE H
Sbjct: 523 GNSTASTKTDRTDEPGAPGAPTGHAVLSPEEKRELDRLLVGFGLE---SAPPMHNHAPGP 579
Query: 466 RPAGGSAVPSSGRHVVPAQVHVNGGA--LASERETDILDDELPNQDGHSAGSMGTLSSLD 523
PA A P GRHVVPAQVHVNG L +ERETDILDDELPNQDGHS GS+GTLSSLD
Sbjct: 580 APARLPAGP--GRHVVPAQVHVNGAGTPLLAERETDILDDELPNQDGHSVGSLGTLSSLD 637
Query: 524 GVTNTSEGGYPEA-----LSPLTNG-----------LDKSYPMEPMVNGGGYPYESASRA 567
G T SE G+ EA LS L NG + Y EP+ N G YPY + +
Sbjct: 638 GTTTASEAGFHEAPRVGSLSSLPNGPASYNGAEKMLKEGLYEAEPLSN-GAYPYSNQNTL 696
Query: 568 GPAH-AGHTAPMRPSYSAQEGLAGYQREGP---HPAWPQPVTTSH--YAHDPSGMFRSQS 621
H A +RPS S QE LAGY + P PAW QP Y +D RSQS
Sbjct: 697 MGHHLRDPLAHLRPSASTQEHLAGYPQRQPASASPAWLQPPVPQPYLYGYDLPSAHRSQS 756
Query: 622 FS-------EAEPQLPPAPVRGGSSREAVQRGLNSWXXXXXXXXXXXXXXXXXERAHLES 674
F EA LP AP R SSREAVQRGLNSW E +H S
Sbjct: 757 FPAVGTAKYEANLALPQAPARSTSSREAVQRGLNSWQQQGGSRPPSQLHDGGLE-SHSPS 815
Query: 675 LVASRPSPQPLAETP--IPSLPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQ 732
L + P P PL P S+PEFPRA S++EIEQSIE L++LMLDL P+ +HKSQ
Sbjct: 816 LSSCSPQPSPLQPMPPHSHSMPEFPRAPSRREIEQSIEALDVLMLDLAPS-----VHKSQ 870
Query: 733 SVPGA-----WPGAXXXXXXXXXXXXXXXHP---LTQSRSGYIPSGHSLGT--------P 776
SVP A P A P + Q RS G S+GT P
Sbjct: 871 SVPSAATRQDKPAAMLSSLSAQRLSGHYAQPTPQVVQPRS----FGTSVGTDPLAKAYSP 926
Query: 777 EPAPRASLESVPPG-------RSYSPYDYQPCLAGPNQDFHXXXXXXXXXXXXXXXXXXX 829
P A+ + P +Y+PY YQ P +
Sbjct: 927 GPLVPAARSTAEPDYTVHEYRETYTPYSYQTV---PEPRSYGSAPASILPLSASYSPAGS 983
Query: 830 XXXXXXXXXXXXXTAQPLLSPK--EATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQXX 887
AQ L K E+ D SR+ EEPLNLEGLVAHRVAGVQ+REK
Sbjct: 984 QQLLVSSPPSPTAPAQSQLPHKGLESYEDLSRS-GEEPLNLEGLVAHRVAGVQSREKSPE 1042
Query: 888 XXXXXXXXXXXSDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLH 947
SD YE SPE SPRSP V +SPE+ TIA NPGGRPKEPHLH
Sbjct: 1043 ESTVPARRRTPSDSHYEKSSPEPGSPRSPTV------LSPEVVSTIAANPGGRPKEPHLH 1096
Query: 948 SYKEAFEEMEGTXXXXXXXXXXXXXXGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQP 1007
SYKEAFEEME GLAKTPLSALGLKPHNPADILLHP G
Sbjct: 1097 SYKEAFEEMESASPSSLTSGGVRSPPGLAKTPLSALGLKPHNPADILLHPVG-------- 1148
Query: 1008 EEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLG 1067
E EG+ EEPRSYVESVARTA G ++ + PA Q G E+P RNG G
Sbjct: 1149 -ELEGEAGADSEEEPRSYVESVARTATTG--------RAGNLPAAQPVGLEVPARNGAFG 1199
Query: 1068 GSFVXXXXXXXXXXXXXADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSA 1127
SF D S+ S+PS E S G TP + E+ +RS + Q +PSA
Sbjct: 1200 NSFTVPSPVSTSSPIHSVDGASLRSYPS-EGSPHGTVTPPHAVAETAYRSPMVSQ-TPSA 1257
Query: 1128 QRNYQSSSP----LPTVGSSYSSPDY--SLQHFSSSPESQARAQFSVAGVHTVPGSPQAR 1181
+YQ+SSP T+GS Y+SPDY F P+++ + Q SV GVH +PGSP+
Sbjct: 1258 HSSYQTSSPSSFQAGTLGSPYASPDYPDGRAGFQPDPQARQQPQVSVVGVHALPGSPRTL 1317
Query: 1182 HRTVGTNTPPSPGFGRRXXXXXXXXXXXXXXXHHQMMGPPGTGFHGSTVSSPQSSAATTP 1241
HRTV TNTPPSPGFGRR + + A+ P
Sbjct: 1318 HRTVATNTPPSPGFGRR---------------------------------AANPAVASVP 1344
Query: 1242 GSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLG 1301
GSP L RH + PGSPSL R H A PGSP
Sbjct: 1345 GSPGLGRHTVSPH----------APPGSPSLAR-------------HQMAAVPPGSPMY- 1380
Query: 1302 RHLXXXXXXXXXXXCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYP 1361
GYS+PE+RRPTLSRQSSASGYQ PSTPSFPVSPAYYP
Sbjct: 1381 -----------------------GYSSPEERRPTLSRQSSASGYQPPSTPSFPVSPAYYP 1417
Query: 1362 GLXXXXXXXXXXXXXFRQGSPT--PALPEKRRMSVGDRAGSLPNYATINGKXXXXXXXXX 1419
G +RQGSPT PALPEKRRMS G+R+ SLPNYAT+NGK
Sbjct: 1418 G-TSTPHSSSPDSAAYRQGSPTPQPALPEKRRMSAGERSNSLPNYATVNGKASSPLSSGM 1476
Query: 1420 XXXXXXXXXXXXHTLPDFSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKD 1479
HTLPDFSK+SMPD SPETRA VKFVQDTSKYWYKP+ISR+QAIALLKD
Sbjct: 1477 SSPSSGSAVAFSHTLPDFSKFSMPDISPETRANVKFVQDTSKYWYKPDISRDQAIALLKD 1536
Query: 1480 QEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLK 1539
+EPGAFIIRDSHSFRGAYGLAMKV+SPPPT+MQQNKKGD+T+ELVRHFLIET PRGVKLK
Sbjct: 1537 REPGAFIIRDSHSFRGAYGLAMKVASPPPTVMQQNKKGDITNELVRHFLIETSPRGVKLK 1596
Query: 1540 GCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAAC 1599
GCPNEPNFG LSALVYQHSI+PLALPCKLVIP+RDP +E KD++ NS DLLKQGAAC
Sbjct: 1597 GCPNEPNFGCLSALVYQHSIMPLALPCKLVIPDRDPMEEKKDAASTTNSATDLLKQGAAC 1656
Query: 1600 NVLFINSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRR 1659
NVLFINSV+MESLTGPQAISKA +ETL ADPTP ATIVHFKVSAQGITLTDNQRKLFFRR
Sbjct: 1657 NVLFINSVEMESLTGPQAISKAVAETLVADPTPTATIVHFKVSAQGITLTDNQRKLFFRR 1716
Query: 1660 HYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASA 1719
HYPLNTVTFCDLDPQERKW KT+G PAKLFGFVARKQGSTT+N CHLFAELDP+QPA+A
Sbjct: 1717 HYPLNTVTFCDLDPQERKWTKTDGSGPAKLFGFVARKQGSTTENVCHLFAELDPDQPAAA 1776
Query: 1720 IVNFVSKVMLNAGQKR 1735
IVNFVS+VML +GQKR
Sbjct: 1777 IVNFVSRVMLGSGQKR 1792
>pir||S27939 tensin - chicken
gb|AAA49087.1| (M74165) tensin [Gallus gallus]
Length = 1733
Score = 1963 bits (5029), Expect = 0.0
Identities = 1091/1817 (60%), Positives = 1202/1817 (66%), Gaps = 220/1817 (12%)
Query: 1 MSVSRTMEDSCELDLVYVTERIIAVSFPSTANE-ENFRSNLREVAQMLKSKHGGNYLLFN 59
MSV+ ME SCELDLVY+TERIIAVS+PSTA E +FRSNLREVA MLKSKHG NY+LFN
Sbjct: 55 MSVTAAMESSCELDLVYITERIIAVSYPSTAEEPRSFRSNLREVAHMLKSKHGDNYVLFN 114
Query: 60 LSERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGR 119
LSERR DI+KLH KVL+FGWPDLHTPALEKICSICKAMDTWLNA HNVVVLHNKGNRGR
Sbjct: 115 LSERRHDISKLHPKVLDFGWPDLHTPALEKICSICKAMDTWLNAAAHNVVVLHNKGNRGR 174
Query: 120 IGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKI 179
+GVV+AAYMHYSNISASADQALDRFAMKRFYEDK+VP+GQPSQ+RY+HYFSGLLSGSIK+
Sbjct: 175 LGVVVAAYMHYSNISASADQALDRFAMKRFYEDKVVPVGQPSQKRYIHYFSGLLSGSIKM 234
Query: 180 NNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPG 239
NNKPLFLHHVIMHGIPNFESKGGCRPFL+IYQAMQPVYTSGIYN+ GDSQT +CITIEPG
Sbjct: 235 NNKPLFLHHVIMHGIPNFESKGGCRPFLKIYQAMQPVYTSGIYNVQGDSQTGICITIEPG 294
Query: 240 LLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGK 299
LLLKGDILLKCYHKKFRSP RDVIFRVQFHTCA+HDL +VFGKEDLD+AF+D+RFPEYGK
Sbjct: 295 LLLKGDILLKCYHKKFRSPTRDVIFRVQFHTCAVHDLDIVFGKEDLDEAFRDERFPEYGK 354
Query: 300 VEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDG---------- 349
VEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSY+NF+ R+D
Sbjct: 355 VEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYENFNIQREDSAEGTWAEPAL 414
Query: 350 ----MEEVVGHTQGPLDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSD 405
+E+ VGHTQGPLDGSLYAKVKKKDSLHGS GAVN R LSA PNHVEHTLSVSSD
Sbjct: 415 PGKHLEKEVGHTQGPLDGSLYAKVKKKDSLHGSIGAVNTARLPLSAAPNHVEHTLSVSSD 474
Query: 406 SGNSTASTKTDKTDEP-VPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLR 464
SGNSTASTKTD+TDEP PGA + A LSP+EKR++DRLL GFGLE A H
Sbjct: 475 SGNSTASTKTDRTDEPGAPGAPTGHAVLSPEEKRDVDRLLVGFGLE---SAAPMHNHAPG 531
Query: 465 SRPAGGSAVPSSGRHVVPAQVHVNGGA--LASERETDILDDELPNQDGHSAGSMGTLSSL 522
PA A P GRHVVPAQVHVNG L +ERETDILDDELPNQDGHS GS+GTLSSL
Sbjct: 532 PAPARLPAGP--GRHVVPAQVHVNGAGTPLLAERETDILDDELPNQDGHSVGSLGTLSSL 589
Query: 523 DGVTNTSEGGYPEA-----LSPLTNG-----------LDKSYPMEPMVNGGGYPYESASR 566
DG T SE G+ EA LS L NG + Y EP+ N G YPY + +
Sbjct: 590 DGTTTASEAGFHEAPRVGSLSSLPNGPASYNGAEKMLKEGLYEAEPLSN-GAYPYSNQNT 648
Query: 567 AGPAH-AGHTAPMRPSYSAQEGLAGYQREGP---HPAWPQPVTTSH--YAHDPSGMFRSQ 620
H A +RPS SAQE LAGY + P PAW QP Y +D RSQ
Sbjct: 649 LMGHHLRDPLAHLRPSRSAQEHLAGYPQRQPASASPAWLQPPVPQPYLYGYDLPSAHRSQ 708
Query: 621 SFS-------EAEPQLPPAPVRGGSSREAVQRGLNSWXXXXXXXXXXXXXXXXXERAHLE 673
SF EA LP AP R SSREAVQRGLNSW E +H
Sbjct: 709 SFPAVGTAKYEANLALPQAPARSTSSREAVQRGLNSWQQQGGSRPPSQLHDGGLE-SHSP 767
Query: 674 SLVASRPSPQPLAETP--IPSLPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKS 731
SL + P P PL P S+PEFPRA S++EIEQSIE L++LMLDL P+ +HKS
Sbjct: 768 SLSSCSPQPSPLQPMPPHSHSMPEFPRAPSRREIEQSIEALDVLMLDLAPS-----VHKS 822
Query: 732 QSVPGA-----WPGAXXXXXXXXXXXXXXXHP---LTQSRSGYIPSGHSLGT-PEPAPRA 782
QSVP A P A P + Q RS G S+GT P P +
Sbjct: 823 QSVPSAATRQDKPAAMLSSLSAQRLSGHYAQPTPQVVQPRS----FGTSVGTDPLAKPYS 878
Query: 783 SLESVPPGRS--------------YSPYDYQPCLAGPNQDFHXXXXXXXXXXXXXXXXXX 828
VP RS Y+PY YQP P +
Sbjct: 879 PGPLVPAARSTAEPDYTVHEYRETYTPYSYQPV---PEPRSYGSAPASILPLSASYSPAG 935
Query: 829 XXXXXXXXXXXXXXTAQPLLSPK--EATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQX 886
AQ L K E+ D SR+ EEPLNLEGLVAHRVAGVQ+REK
Sbjct: 936 SQQLLVSSPPSPTAPAQSQLPHKGLESYEDLSRS-GEEPLNLEGLVAHRVAGVQSREKSP 994
Query: 887 XXXXXXXXXXXXSDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHL 946
SD YE SPE SPRSP V +SPE+ TIA NPGGRPKEPHL
Sbjct: 995 EESTVPARRRTPSDSHYEKSSPEPGSPRSPTV------LSPEVVSTIAANPGGRPKEPHL 1048
Query: 947 HSYKEAFEEMEGTXXXXXXXXXXXXXXGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQ 1006
HSYKEAFEEME GLAKTPLSALGLKPHNPADILLHP G
Sbjct: 1049 HSYKEAFEEMESASPSSLTSGGVRSPPGLAKTPLSALGLKPHNPADILLHPVG------- 1101
Query: 1007 PEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTL 1066
EPRSYVESVARTA G ++ + PA Q G E+P RNG
Sbjct: 1102 --------------EPRSYVESVARTATTG--------RAGNLPAAQPVGLEVPARNGAF 1139
Query: 1067 GGSFVXXXXXXXXXXXXXADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPS 1126
G SF D S+ S+PS E S G TP + E+ +RS + Q +PS
Sbjct: 1140 GNSFTVPSPVSTSSPIHSVDGASLRSYPS-EGSPHGTVTPPHAVAETAYRSPMVSQ-TPS 1197
Query: 1127 AQRNYQSSSP----LPTVGSSYSSPDY--SLQHFSSSPESQARAQFSVAGVHTVPGSPQA 1180
A +YQ+SSP T+GS Y+SPDY F P+++ + Q SV GVH +PGSP+
Sbjct: 1198 AHSSYQTSSPSSFQAGTLGSPYASPDYPDGRGGFQPDPQARQQPQVSVVGVHALPGSPRT 1257
Query: 1181 RHRTVGTNTPPSPGFGRRXXXXXXXXXXXXXXXHHQMMGPPGTGFHGSTVSSPQSSAATT 1240
HRTV TNTPPSPGFGRR + + A+
Sbjct: 1258 LHRTVATNTPPSPGFGRR---------------------------------AANPAVASV 1284
Query: 1241 PGSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSL 1300
PGSP L RH + PGSPSL R H A PGSP
Sbjct: 1285 PGSPGLGRHTVSPH----------APPGSPSLAR-------------HQMAAVPPGSPMY 1321
Query: 1301 GRHLXXXXXXXXXXXCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYY 1360
GYS+PE+RRPTLSRQSSASGYQ PSTPSFPVSPAYY
Sbjct: 1322 ------------------------GYSSPEERRPTLSRQSSASGYQPPSTPSFPVSPAYY 1357
Query: 1361 PGLXXXXXXXXXXXXXFRQGSPT--PALPEKRRMSVGDRAGSLPNYATINGKXXXXXXXX 1418
PG +RQGSPT PALPEKRRMS G+R+ SLPNYAT+NGK
Sbjct: 1358 PG-TSTPHSSSPDSAAYRQGSPTPQPALPEKRRMSAGERSNSLPNYATVNGKASSPLSSG 1416
Query: 1419 XXXXXXXXXXXXXHTLPDFSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLK 1478
HTLPDFSK+SMPD SPETRA VKFVQDTSKYWYKP+ISREQAIALLK
Sbjct: 1417 MSSPSSGSAVAFSHTLPDFSKFSMPDISPETRANVKFVQDTSKYWYKPDISREQAIALLK 1476
Query: 1479 DQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKL 1538
D+EPGAFIIRDSHSFRGAYGLAMKV+SPPPT+MQQNKKGD+T+ELVRHFLIET PRGVKL
Sbjct: 1477 DREPGAFIIRDSHSFRGAYGLAMKVASPPPTVMQQNKKGDITNELVRHFLIETSPRGVKL 1536
Query: 1539 KGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAA 1598
KGCPNEPNFG LSALVYQHSI+PLALPCKLVIP+RDP +E KD++ NS DLLKQGAA
Sbjct: 1537 KGCPNEPNFGCLSALVYQHSIMPLALPCKLVIPDRDPMEEKKDAASTTNSATDLLKQGAA 1596
Query: 1599 CNVLFINSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFR 1658
CNVLFINSV+MESLTGPQAISKA +ETL ADPTP ATIVHFKVSAQGITLTDNQRKLFFR
Sbjct: 1597 CNVLFINSVEMESLTGPQAISKAVAETLVADPTPTATIVHFKVSAQGITLTDNQRKLFFR 1656
Query: 1659 RHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPAS 1718
RHYPLNTVTFCDLDPQERKW KT+G PAKLFGFVARKQGSTTDN CHLFAELDP+QPA+
Sbjct: 1657 RHYPLNTVTFCDLDPQERKWTKTDGSGPAKLFGFVARKQGSTTDNVCHLFAELDPDQPAA 1716
Query: 1719 AIVNFVSKVMLNAGQKR 1735
AIVNFVS+VML +GQKR
Sbjct: 1717 AIVNFVSRVMLGSGQKR 1733
>ref|XP_002286.1| hypothetical protein FLJ10923 [Homo sapiens]
Length = 460
Score = 779 bits (1991), Expect = 0.0
Identities = 378/399 (94%), Positives = 379/399 (94%), Gaps = 20/399 (5%)
Query: 1 MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL 60
MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNL
Sbjct: 82 MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNL-------------------- 121
Query: 61 SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRI 120
SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRI
Sbjct: 122 SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRI 181
Query: 121 GVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKIN 180
GVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIK+N
Sbjct: 182 GVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMN 241
Query: 181 NKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL 240
NKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL
Sbjct: 242 NKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL 301
Query: 241 LLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV 300
LLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV
Sbjct: 302 LLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV 361
Query: 301 EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGP 360
EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGP
Sbjct: 362 EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGP 421
Query: 361 LDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHT 399
LDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHT
Sbjct: 422 LDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHT 460
>ref|NP_060744.1| hypothetical protein FLJ10923 [Homo sapiens]
dbj|BAA91910.1| (AK001785) unnamed protein product [Homo sapiens]
Length = 328
Score = 626 bits (1597), Expect = e-178
Identities = 297/298 (99%), Positives = 298/298 (99%)
Query: 97 MDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVP 156
MDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVP
Sbjct: 1 MDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVP 60
Query: 157 IGQPSQRRYVHYFSGLLSGSIKINNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPV 216
IGQPSQRRYVHYFSGLLSGSIK+NNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPV
Sbjct: 61 IGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPV 120
Query: 217 YTSGIYNIPGDSQTSVCITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDL 276
YTSGIYNIPGDSQTSVCITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDL
Sbjct: 121 YTSGIYNIPGDSQTSVCITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDL 180
Query: 277 GVVFGKEDLDDAFKDDRFPEYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRW 336
GVVFGKEDLDDAFKDDRFPEYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRW
Sbjct: 181 GVVFGKEDLDDAFKDDRFPEYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRW 240
Query: 337 DSYDNFSGHRDDGMEEVVGHTQGPLDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPN 394
DSYDNFSGHRDDGMEEVVGHTQGPLDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPN
Sbjct: 241 DSYDNFSGHRDDGMEEVVGHTQGPLDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPN 298
>pir||T17293 hypothetical protein DKFZp434G162.1 - human (fragment)
emb|CAB55983.1| (AL117537) hypothetical protein [Homo sapiens]
Length = 270
Score = 550 bits (1403), Expect = e-155
Identities = 269/270 (99%), Positives = 270/270 (99%)
Query: 1466 PEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVR 1525
PEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVR
Sbjct: 1 PEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVR 60
Query: 1526 HFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDSSGP 1585
HFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDSSGP
Sbjct: 61 HFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDSSGP 120
Query: 1586 ANSTADLLKQGAACNVLFINSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQG 1645
ANSTADLLKQGAACNVLF+NSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQG
Sbjct: 121 ANSTADLLKQGAACNVLFVNSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQG 180
Query: 1646 ITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNAC 1705
ITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNAC
Sbjct: 181 ITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNAC 240
Query: 1706 HLFAELDPNQPASAIVNFVSKVMLNAGQKR 1735
HLFAELDPNQPASAIVNFVSKVMLNAGQKR
Sbjct: 241 HLFAELDPNQPASAIVNFVSKVMLNAGQKR 270
>emb|CAA46992.1| (X66286) tensin [Gallus gallus]
Length = 276
Score = 507 bits (1292), Expect = e-142
Identities = 241/276 (87%), Positives = 259/276 (93%)
Query: 1460 SKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDM 1519
SKYWYKP+ISREQAIALLKD+EPGAFIIRDSHSFRGAYGLAMKV+SPPPT+MQQNKKGD+
Sbjct: 1 SKYWYKPDISREQAIALLKDREPGAFIIRDSHSFRGAYGLAMKVASPPPTVMQQNKKGDI 60
Query: 1520 THELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDES 1579
T+ELVRHFLIET PRGVKLKGCPNEPNFG LSALVYQHSI+PLALPCKLVIP+RDP +E
Sbjct: 61 TNELVRHFLIETSPRGVKLKGCPNEPNFGCLSALVYQHSIMPLALPCKLVIPDRDPMEEK 120
Query: 1580 KDSSGPANSTADLLKQGAACNVLFINSVDMESLTGPQAISKATSETLAADPTPAATIVHF 1639
KD++ NS DLLKQGAACNVLFINSV+MESLTGPQAISKA +ETL ADPTP ATIVHF
Sbjct: 121 KDAASTTNSATDLLKQGAACNVLFINSVEMESLTGPQAISKAVAETLVADPTPTATIVHF 180
Query: 1640 KVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGS 1699
KVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKW KT+G PAKLFGFVARKQGS
Sbjct: 181 KVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWTKTDGSGPAKLFGFVARKQGS 240
Query: 1700 TTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR 1735
TTDN CHLFAELDP+QPA+AIVNFVS+VML +GQKR
Sbjct: 241 TTDNVCHLFAELDPDQPAAAIVNFVSRVMLGSGQKR 276
>dbj|BAB15041.1| (AK024948) unnamed protein product [Homo sapiens]
Length = 235
Score = 482 bits (1227), Expect = e-134
Identities = 234/235 (99%), Positives = 235/235 (99%)
Query: 1501 MKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSII 1560
MKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSII
Sbjct: 1 MKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSII 60
Query: 1561 PLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAACNVLFINSVDMESLTGPQAISK 1620
PLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAACNVLF+NSVDMESLTGPQAISK
Sbjct: 61 PLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAACNVLFVNSVDMESLTGPQAISK 120
Query: 1621 ATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMK 1680
ATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMK
Sbjct: 121 ATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMK 180
Query: 1681 TEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR 1735
TEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR
Sbjct: 181 TEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR 235
>dbj|BAA83027.1| (AB028998) KIAA1075 protein [Homo sapiens]
Length = 1400
Score = 480 bits (1221), Expect = e-134
Identities = 243/455 (53%), Positives = 321/455 (70%), Gaps = 17/455 (3%)
Query: 2 SVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLS 61
S+ ME +LDL YVTERI+A +FP+ +E+ R +LRE+A +L+SKH YLLFNLS
Sbjct: 111 SLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLS 170
Query: 62 ERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIG 121
E+R D+T+L+ KV +FGWP+LH P L+K+CSICKAM+TWL+ADP +VVVL+ KGN+G++G
Sbjct: 171 EKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLG 230
Query: 122 VVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKINN 181
V+++AYMHYS ISA ADQAL M++F EDK+ QPSQRRY+ YFSGLLSGSI++N+
Sbjct: 231 VIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNS 290
Query: 182 KPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLL 241
PLFLH+V++ +P FE G +PFL+IYQ+MQ VYTSG+Y+I G +CI++EP LL
Sbjct: 291 SPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALL 350
Query: 242 LKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKVE 301
LKGD+++ CYHK R R ++FRVQFHTC IH + F K+ LD+A+ D+RFP VE
Sbjct: 351 LKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVE 410
Query: 302 FVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGPL 361
FVFS PEKI+G N PSVSVDYNT++P +RWDSY+NF+ H +D ++ + HT+GPL
Sbjct: 411 FVFSSSPEKIKGSTP-RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPL 469
Query: 362 DGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEP 421
DGS YA+V++ T P S P LSVSSDSG+S ST T +
Sbjct: 470 DGSPYAQVQRPP---------RQTPPAPSPEP-PPPPMLSVSSDSGHS--STLTTEPAAE 517
Query: 422 VPGASSATAALSPQEKRELDRLLSGFGLEREKQGA 456
PG TAA E++ELDRLL G G+ +GA
Sbjct: 518 SPGRPPPTAA----ERQELDRLLGGCGVASGGRGA 548
Score = 390 bits (991), Expect = e-107
Identities = 263/655 (40%), Positives = 351/655 (53%), Gaps = 107/655 (16%)
Query: 1116 RSGSLGQPSPSAQRNYQSSSPLPTV--GSSYSSPDYSLQHFSSSPESQARAQFSVA---- 1169
R+GS+ SP ++ + S +PT G Y P + S+ P + A + V+
Sbjct: 818 RAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLA---SAGPLASAESLEPVSWREG 874
Query: 1170 --GVHTVPGSPQ-----ARHRTVGTNTP---PSPGFGRRXXXXXXXXXXXXXXXHHQMMG 1219
G T+P SP+ A G +TP SP G+ G
Sbjct: 875 PSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPG 934
Query: 1220 PPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATT--PGSPS---LGR 1274
+ P S A T +P L P+G + V+ T P SPS R
Sbjct: 935 E----------ALPPVSQAGTGKAPEL---PSGSGPEPLAPSPVSPTFPPSSPSDWPQER 981
Query: 1275 HPGAHQGNLASGLHSNAIASPGSPSLGRHLXXXXXXXXXXXCLDRHVAYGGYSTPEDR-- 1332
PG H ASP SP RH + G P D
Sbjct: 982 SPGGHSDG----------ASPRSP------------VPTTLPGLRHAPWQGPRGPPDSPD 1019
Query: 1333 ----RPTLSRQ----SSASGYQAPSTPSFPVSPAYYPGLXXXXXXXXXXXXXFRQGSPTP 1384
P S+ +S Q+ TP+FP++ +Y G P
Sbjct: 1020 GSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTN-----------------GLSQP 1062
Query: 1385 ALPEKRRM-SVGDRAGSL-PNYATINGKXXXXXXXXXXXXXXXXXXXXXHTLPDFSKYSM 1442
LPEKR + G + G P A+ + L D +
Sbjct: 1063 PLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPL------------LSDNVPQTP 1110
Query: 1443 PDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMK 1502
+ E+++ VKFVQDTSK+WYKP +SR+QAIALLKD++PGAF+IRDSHSF+GAYGLA+K
Sbjct: 1111 EPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALK 1170
Query: 1503 VSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPL 1562
V++PPP+ Q KGD +LVRHFLIETGP+GVK+KGCP+EP FGSLSALV QHSI P+
Sbjct: 1171 VATPPPSA--QPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPI 1228
Query: 1563 ALPCKLVIPNRDPTDESKDSSGPAN--STADLLKQGAACNVLFINSVDMESLTGPQAISK 1620
+LPC L I ++DP +E+ ++ P N + ADLL+QGAAC+VL++ SV+ ESLTGPQA+++
Sbjct: 1229 SLPCCLRILSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVAR 1288
Query: 1621 ATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMK 1680
A+S L+ P P +VHFKVSAQGITLTDNQRKLFFRRHYP+N++TF DPQ+R+W
Sbjct: 1289 ASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTN 1348
Query: 1681 TEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR 1735
+ G +K+FGFVA+K GS +N CHLFAELDP+QPA AIV F++KV+L GQ++
Sbjct: 1349 PD-GTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLL--GQRK 1400
>pir||T46500 hypothetical protein DKFZp434D098.1 - human (fragment)
emb|CAB70815.1| (AL137564) hypothetical protein [Homo sapiens]
Length = 649
Score = 388 bits (985), Expect = e-106
Identities = 263/655 (40%), Positives = 351/655 (53%), Gaps = 109/655 (16%)
Query: 1116 RSGSLGQPSPSAQRNYQSSSPLPTV--GSSYSSPDYSLQHFSSSPESQARAQFSVA---- 1169
R+GS+ SP ++ + S +PT G Y P + S+ P + A + V+
Sbjct: 69 RAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLA---SAGPLASAESLEPVSWREG 125
Query: 1170 --GVHTVPGSPQ-----ARHRTVGTNTP---PSPGFGRRXXXXXXXXXXXXXXXHHQMMG 1219
G T+P SP+ A G +TP SP G+ G
Sbjct: 126 PSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPG 185
Query: 1220 PPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATT--PGSPS---LGR 1274
+ P S A T +P L P+G + V+ T P SPS R
Sbjct: 186 E----------ALPPVSQAGTGKAPEL---PSGSGPEPLAPSPVSPTFPPSSPSDWPQER 232
Query: 1275 HPGAHQGNLASGLHSNAIASPGSPSLGRHLXXXXXXXXXXXCLDRHVAYGGYSTPEDR-- 1332
PG H ASP SP RH + G P D
Sbjct: 233 SPGGHSDG----------ASPRSP------------VPTTLPGLRHAPWQGPRGPPDSPD 270
Query: 1333 ----RPTLSRQ----SSASGYQAPSTPSFPVSPAYYPGLXXXXXXXXXXXXXFRQGSPTP 1384
P LS+ +S Q+ TP+FP++ +Y G P
Sbjct: 271 GSPLTPVLSQMPWLVASPEPPQSSPTPAFPLAASYDTN-----------------GLSQP 313
Query: 1385 ALPEKRRM-SVGDRAGSL-PNYATINGKXXXXXXXXXXXXXXXXXXXXXHTLPDFSKYSM 1442
LPEKR + G + G P A+ + L D +
Sbjct: 314 PLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPL------------LSDNVPQTP 361
Query: 1443 PDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMK 1502
+ E+++ VKFVQDTSK+WYKP +SR+QAIALLKD++PGAF+IRDSHSF+GAYGLA+K
Sbjct: 362 EPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALK 421
Query: 1503 VSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPL 1562
V++PPP+ Q KGD +LVRHFLIETGP+GVK+KGCP+EP FGSLSALV QHSI P+
Sbjct: 422 VATPPPSA--QPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPI 479
Query: 1563 ALPCKLVIPNRDPTDESKDSSGPAN--STADLLKQGAACNVLFINSVDMESLTGPQAISK 1620
+LPC L IP++DP +E+ ++ P N + ADLL+Q AC+VL++ SV+ ESLTGPQA+++
Sbjct: 480 SLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQ--ACSVLYLTSVETESLTGPQAVAR 537
Query: 1621 ATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMK 1680
A+S L+ P P +VHFKVSAQGITLTDNQRKLFFRRHYP+N++TF DPQ+R+W
Sbjct: 538 ASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTN 597
Query: 1681 TEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR 1735
+ G +K+FGFVA+K GS +N CHLFAELDP+QPA AIV F++KV+L GQ++
Sbjct: 598 PD-GTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLL--GQRK 649
>dbj|BAB14682.1| (AK023794) unnamed protein product [Homo sapiens]
Length = 261
Score = 383 bits (974), Expect = e-105
Identities = 189/262 (72%), Positives = 222/262 (84%), Gaps = 5/262 (1%)
Query: 1476 LLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKK-GDMTHELVRHFLIETGPR 1534
+LKD+EPG+FI+RDSHSFRGAYGLAMKV++PPP+++Q NKK GD+ +ELVRHFLIE P+
Sbjct: 1 MLKDKEPGSFIVRDSHSFRGAYGLAMKVATPPPSVLQLNKKAGDLANELVRHFLIECTPK 60
Query: 1535 GVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDSSGP--ANSTADL 1592
GV+LKGC NEP FGSL+ALV QHSI PLALPCKL+IP RDP +E +SS ANS A+L
Sbjct: 61 GVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAESSPQTAANSAAEL 120
Query: 1593 LKQGAACNVLFINSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQ 1652
LKQGAACNV ++NSV+MESLTG QAI KA S TL +P P +T+VHFKVSAQGITLTDNQ
Sbjct: 121 LKQGAACNVWYLNSVEMESLTGHQAIQKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQ 180
Query: 1653 RKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELD 1712
RKLFFRRHYP+N+V FC LDPQ+RKW+K G +K+FGFVARKQGS TDN CHLFAE D
Sbjct: 181 RKLFFRRHYPVNSVIFCALDPQDRKWIK--DGPSSKVFGFVARKQGSATDNVCHLFAEHD 238
Query: 1713 PNQPASAIVNFVSKVMLNAGQK 1734
P QPASAIVNFVSKVM+ + +K
Sbjct: 239 PVQPASAIVNFVSKVMIGSPKK 260
>pir||T29328 hypothetical protein M01E11.7b - Caenorhabditis elegans
gb|AAB37834.1| (U80450) coded for by C. elegans cDNA yk33h12.3; coded for by C.
elegans cDNA yk33h12.5; Similar to tensin; coded for by
C. elegans cDNA yk33h12.3; coded for by C. elegans cDNA
yk33h12.5 [Caenorhabditis elegans]
Length = 417
Score = 307 bits (777), Expect = 9e-82
Identities = 163/284 (57%), Positives = 207/284 (72%), Gaps = 19/284 (6%)
Query: 1455 FVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQN 1514
FV+DTSKYWYKP ISREQAI +L+D+ PG F++RDS+SF GA+GLA+KVS+PPP +
Sbjct: 138 FVKDTSKYWYKPTISREQAINMLRDKPPGTFVVRDSNSFPGAFGLALKVSTPPPGV---- 193
Query: 1515 KKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRD 1574
GD + ELVRHFLIE P+GVKLKGC NEP FGSLSALVYQHSI LALP KLV+P+ D
Sbjct: 194 NPGDGS-ELVRHFLIEPSPKGVKLKGCNNEPVFGSLSALVYQHSITALALPTKLVLPDFD 252
Query: 1575 PTDESKDSSGPANSTADLLKQGAACNVLFINSVDMESLTGPQAISK--ATSETLAADPTP 1632
P + S +T LL+QGAACNV+++ SVD+ESLTG + + + AT A +
Sbjct: 253 PAATPEHLS----ATQALLEQGAACNVVYVGSVDVESLTGNECVKRSIATCSQRAINGDS 308
Query: 1633 AATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEG-------GA 1685
A VHFKVS+QG+TLTDN RK+FFRRH+ + +V F +DP ER++ T A
Sbjct: 309 RAVSVHFKVSSQGVTLTDNTRKVFFRRHFNVQSVIFAGMDPIERRFENTRALGFHDGCIA 368
Query: 1686 PAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVML 1729
A+LF FVAR S+++NACH+FAEL+P QP SA+VNF++KVML
Sbjct: 369 QARLFAFVARIP-SSSENACHVFAELEPEQPGSAVVNFINKVML 411
>pir||T29327 hypothetical protein M01E11.7a - Caenorhabditis elegans
gb|AAB37833.1| (U80450) coded for by C. elegans cDNA yk126c6.3; coded for by C.
elegans cDNA yk125d8.5; coded for by C. elegans cDNA
yk126c6.5 [Caenorhabditis elegans]
Length = 1110
Score = 307 bits (777), Expect = 9e-82
Identities = 163/284 (57%), Positives = 207/284 (72%), Gaps = 19/284 (6%)
Query: 1455 FVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQN 1514
FV+DTSKYWYKP ISREQAI +L+D+ PG F++RDS+SF GA+GLA+KVS+PPP +
Sbjct: 831 FVKDTSKYWYKPTISREQAINMLRDKPPGTFVVRDSNSFPGAFGLALKVSTPPPGV---- 886
Query: 1515 KKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRD 1574
GD + ELVRHFLIE P+GVKLKGC NEP FGSLSALVYQHSI LALP KLV+P+ D
Sbjct: 887 NPGDGS-ELVRHFLIEPSPKGVKLKGCNNEPVFGSLSALVYQHSITALALPTKLVLPDFD 945
Query: 1575 PTDESKDSSGPANSTADLLKQGAACNVLFINSVDMESLTGPQAISK--ATSETLAADPTP 1632
P + S +T LL+QGAACNV+++ SVD+ESLTG + + + AT A +
Sbjct: 946 PAATPEHLS----ATQALLEQGAACNVVYVGSVDVESLTGNECVKRSIATCSQRAINGDS 1001
Query: 1633 AATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEG-------GA 1685
A VHFKVS+QG+TLTDN RK+FFRRH+ + +V F +DP ER++ T A
Sbjct: 1002 RAVSVHFKVSSQGVTLTDNTRKVFFRRHFNVQSVIFAGMDPIERRFENTRALGFHDGCIA 1061
Query: 1686 PAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVML 1729
A+LF FVAR S+++NACH+FAEL+P QP SA+VNF++KVML
Sbjct: 1062 QARLFAFVARIP-SSSENACHVFAELEPEQPGSAVVNFINKVML 1104
>gb|AAF54393.1| (AE003683) CG9379 gene product [Drosophila melanogaster]
Length = 720
Score = 263 bits (664), Expect = 2e-68
Identities = 134/276 (48%), Positives = 181/276 (65%), Gaps = 13/276 (4%)
Query: 1453 VKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQ 1512
V+F + +S++WYKP ++RE AIALL +PG F++RDS +++ +YGL ++VS PPP
Sbjct: 448 VQFARSSSQFWYKPNLTREDAIALLASAQPGTFLVRDSTTYKDSYGLVVRVSQPPPG--- 504
Query: 1513 QNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPN 1572
+ ELVRHFLIE GV LKGC +EP F SLSALV++HSI LALPC L +P+
Sbjct: 505 -------SQELVRHFLIEPTKGGVHLKGCDDEPVFTSLSALVFEHSISQLALPCLLRLPD 557
Query: 1573 RDPTDESKDSSGPANSTADLLKQGAACNVLFINSVDMESLTGPQAISKATSETLAADPTP 1632
RD + ++ PA LL GAA NVL++ S D ESLTG +AI KA + P P
Sbjct: 558 RDIVPPVRATT-PAQQ--HLLAHGAATNVLWLYSCDTESLTGNEAIRKAIRQMYGQQPLP 614
Query: 1633 AATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGF 1692
T VHFKVS+QGITLTDN RK FFR+HY + ++ C +DP+ R W +F F
Sbjct: 615 QPTEVHFKVSSQGITLTDNTRKKFFRKHYKADVISHCAIDPENRMWTSEGESDKKTIFAF 674
Query: 1693 VARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVM 1728
VAR+ S+TDN CH+F +L +QPA+AIV+F ++ +
Sbjct: 675 VARRSHSSTDNQCHVFCDLSVSQPAAAIVSFANRTL 710
>gb|AAB23490.1| insertin=tensin homolog [chickens, gizzard, smooth muscle, Peptide
Partial, 351 aa]
Length = 351
Score = 233 bits (588), Expect = 1e-59
Identities = 158/376 (42%), Positives = 184/376 (48%), Gaps = 47/376 (12%)
Query: 767 IPSGHSLGTPEPAPRASLE---SVPPGR-SYSPYDYQPCLAGPNQDFHXXXXXXXXXXXX 822
+ +S G PA R++ E +V R +Y+PY YQP P +
Sbjct: 12 LAKAYSPGPLVPAARSTAEPDYTVHEYRETYTPYSYQPV---PEPRSYGSAPASILPLSA 68
Query: 823 XXXXXXXXXXXXXXXXXXXXTAQPLLSPK--EATSDPSRTPEEEPLNLEGLVAHRVAGVQ 880
AQ L K E+ D SR+ EE PLNLEGLVAHRVAGVQ
Sbjct: 69 SYSPAGSQQLLVSSPPSPTAPAQSQLPHKGLESYEDLSRSGEE-PLNLEGLVAHRVAGVQ 127
Query: 881 AREKQXXXXXXXXXXXXXSDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGR 940
+REK SD YE SPE SPRSP V +SPE+ TIA NPGGR
Sbjct: 128 SREKSPEESTVPARRRTPSDSHYEKSSPEPGSPRSPTV------LSPEVVSTIAANPGGR 181
Query: 941 PKEPHLHSYKEAFEEMEGTXXXXXXXXXXXXXXGLAKTPLSALGLKPHNPADILLHPTGV 1000
PKEPHLHSYKEAFEEME GLAKTPLSALGLKPHNPADILLHP G
Sbjct: 182 PKEPHLHSYKEAFEEMESASPSSLTSGGVRSPPGLAKTPLSALGLKPHNPADILLHPVG- 240
Query: 1001 TRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIP 1060
EPRSYVESVARTA G ++ + PA Q G E+P
Sbjct: 241 --------------------EPRSYVESVARTATTG--------RAGNLPAAQPVGLEVP 272
Query: 1061 LRNGTLGGSFVXXXXXXXXXXXXXADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSL 1120
RNG G SF D S+ S+PS E S G TP + E+ +RS +
Sbjct: 273 ARNGAFGNSFTVPSPVSTSSPIHSVDGASLRSYPS-EGSPHGTVTPPHAVAETAYRSPMV 331
Query: 1121 GQPSPSAQRNYQSSSP 1136
Q +PSA +YQ+SSP
Sbjct: 332 SQ-TPSAHSSYQTSSP 346
>gb|AAA67648.1| (U26310) tensin [Rattus norvegicus]
Length = 107
Score = 214 bits (540), Expect = 6e-54
Identities = 103/106 (97%), Positives = 104/106 (97%)
Query: 1630 PTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKL 1689
P AATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKL
Sbjct: 2 PMLAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKL 61
Query: 1690 FGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR 1735
FGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVML+AGQKR
Sbjct: 62 FGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLSAGQKR 107
>sp|P91301|YLPK_CAEEL HYPOTHETICAL 30.3 KD PROTEIN F46F11.3 IN CHROMOSOME I
pir||T25762 hypothetical protein F46F11.3 - Caenorhabditis elegans
gb|AAB42265.1| (U88173) similar to chicken tensin (SP:Q04205) [Caenorhabditis
elegans]
Length = 264
Score = 166 bits (416), Expect = 2e-39
Identities = 92/245 (37%), Positives = 144/245 (58%), Gaps = 12/245 (4%)
Query: 7 MEDSCE-LDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSERRP 65
M+D E + + Y+T R+I +S S +E F +L + +Q +++ H + ++N+S+RR
Sbjct: 25 MKDRKEGVQVEYITSRLIVLSCTSETSERKFVESLLKASQQIQNAHNKHIRVWNVSQRRH 84
Query: 66 DITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIA 125
DI+ + FGWP P+LEK+C+ICK +D W+ P N+ V+ KG R +V+
Sbjct: 85 DISS-SLDAIPFGWPSETAPSLEKLCTICKNLDQWMLEHPLNIAVIFCKGGLERCAIVVN 143
Query: 126 AYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKINNKPLF 185
A+M ++ ISA+ D DRF+M+RF E + P G PS +RY+ YFS LLSG I +N+ PL+
Sbjct: 144 AFMRFNAISATDDSVDDRFSMQRFSERFLGPDGPPSYKRYLGYFSSLLSGRISVNSDPLY 203
Query: 186 LHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLKGD 245
LH++I + FE FL+IY+ + PVY S + S+ ++ L L+GD
Sbjct: 204 LHNII---LTFFEP---INVFLKIYERLVPVYQSKTVALNKSSK----FEMDGSLKLRGD 253
Query: 246 ILLKC 250
I KC
Sbjct: 254 IFFKC 258
>pdb|1D5R|A Chain A, Crystal Structure Of The Pten Tumor Suppressor
Length = 324
Score = 146 bits (366), Expect = 1e-33
Identities = 98/298 (32%), Positives = 151/298 (49%), Gaps = 15/298 (5%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R ED +LDL Y+ IIA+ FP+ E +R+N+ +V + L SKH +Y ++NL +ER
Sbjct: 9 RYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAER 68
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D K + +V ++ + D + P LE I C+ +D WL+ D ++V +H K +GR GV+
Sbjct: 69 HYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVM 128
Query: 124 IAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKINNKP 183
I AY+ + A +ALD + R + K V I PSQRRYV+Y+S LL +
Sbjct: 129 ICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTI--PSQRRYVYYYSYLLKNHLDYRPVA 186
Query: 184 LFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLK 243
L H ++ IP F S G C P + Q +Y+S + + +P L +
Sbjct: 187 LLFHKMMFETIPMF-SGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQP-LPVC 244
Query: 244 GDILLKCYHKKFRSPARDVIFRVQFHTCAI----------HDLGVVFGKEDLDDAFKD 291
GDI ++ +HK+ + +D +F +T I L + K DLD A KD
Sbjct: 245 GDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEEVDNDKEYLVLTLTKNDLDKANKD 302
>ref|NP_005246.1| cyclin G associated kinase [Homo sapiens]
dbj|BAA22623.1| (D88435) HsGAK [Homo sapiens]
Length = 1311
Score = 146 bits (364), Expect = 2e-33
Identities = 164/668 (24%), Positives = 272/668 (40%), Gaps = 61/668 (9%)
Query: 12 ELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSERRPDITKLH 71
+LD+ Y+T RI +SFP+ E ++N+ +V L SKH G+Y ++NLS R ++ H
Sbjct: 407 DLDISYITSRIAVMSFPAEGVESALKNNIEDVRLFLDSKHPGHYAVYNLSPRTYRPSRFH 466
Query: 72 AKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYS 131
+V E GW P L + +IC+ M WL D NV V+H R V + +++ +
Sbjct: 467 NRVSECGWAARRAPHLHTLYNICRNMHAWLRQDHKNVCVVHCMDGRAASAVAVCSFLCFC 526
Query: 132 NISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGS-IKINNKPLFLHHVI 190
+ ++A+ A+ F+MKR P PS +RY+ Y +++ I ++KP+ + V+
Sbjct: 527 RLFSTAEAAVYMFSMKR-----CPPGIWPSHKRYIEYMCDMVAEEPITPHSKPILVRAVV 581
Query: 191 MHGIPNF-ESKGGCRPFLRIYQAMQPV-YTSGIYNIPGDSQTSVCITIEP-GLLLKGDIL 247
M +P F + + GCRPF +Y + V TS Y+ D + + P G+ ++GD+L
Sbjct: 582 MTPVPLFSKQRSGCRPFCEVYVGDERVASTSQEYDKMRDFKIEDGKAVIPLGVTVQGDVL 641
Query: 248 LKCYHKKF-------RSPARDVIFRVQFHTCAI--HDLGVVFGKEDLDDAFKDDRFPEYG 298
+ YH + A +F++QFHT + + V F K DLD +++P+
Sbjct: 642 IVIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKYPDLF 701
Query: 299 KVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLI----RWDSYDNFSGHRDDGMEEVV 354
+V P + E P + +P I R + D S +
Sbjct: 702 QVNLEVEVEP---RDRPSREAPPWENSSMRGLNPKILFSSREEQQDILSKFGKPELPRQP 758
Query: 355 GHTQGPLDGSLYAKVKKKDSLHGSTGAVNATR--PTLSATPNHVEHTLSVSSDSGNSTAS 412
G T G+ + + DS + + +A+R TL T + ++ S S ++
Sbjct: 759 GSTAQYDAGAGSPEAEPTDSDSPPSSSADASRFLHTLDWQEEKEAETGAENASSKESESA 818
Query: 413 TKTDKTDEPVPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSA 472
D+ + V + + QE R D G +Q ++ + P
Sbjct: 819 LMEDRDESEVSDEGGSPISSEGQEPR-ADPEPPGLAAGLVQQDLVFEVETPAVLP---EP 874
Query: 473 VP-SSGRHVVPAQVHVNGG-------ALASERETDILDDELPNQDGHSAGSMGTLSSLD- 523
VP G ++ V G A TD+L L + S G L S D
Sbjct: 875 VPQEDGVDLLGLHSEVGAGPAVPPQACKAPSSNTDLLSCLLGPPEAASQGPPEDLLSEDP 934
Query: 524 ----------GVTNTSEGGYPEALSPL-----TNGLDKSYPMEPMVNGGGYPYESASRAG 568
V +T GG P A P ++G + P + G +S +
Sbjct: 935 LLLASPAPPLSVQSTPRGGPPAAADPFGPLLPSSGNNSQPCSNPDLFGEFLNSDSVTVPP 994
Query: 569 PAHAGHTAPMRPSYSAQEGLAGYQREGPHPAWPQPVTTSHYAHDPSGMFRSQSFSEAEPQ 628
+ H+AP PS SA + G P P +T S D G + + + + A
Sbjct: 995 SFPSAHSAP-PPSCSAD-----FLHLGDLPGEPSKMTASSSNPDLLGGWAAWTETAASAV 1048
Query: 629 LPPAPVRG 636
P G
Sbjct: 1049 APTPATEG 1056
>ref|XP_003450.1| cyclin G associated kinase [Homo sapiens]
Length = 701
Score = 145 bits (363), Expect = 3e-33
Identities = 93/310 (30%), Positives = 157/310 (50%), Gaps = 18/310 (5%)
Query: 12 ELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSERRPDITKLH 71
+LD+ Y+T RI +SFP+ E ++N+ +V L SKH G+Y ++NLS R ++ H
Sbjct: 361 DLDISYITSRIAVMSFPAEGVESALKNNIEDVRLFLDSKHPGHYAVYNLSPRTYRPSRFH 420
Query: 72 AKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYS 131
+V E GW P L + +IC+ M WL D NV V+H R V + +++ +
Sbjct: 421 NRVSECGWAARRAPHLHTLYNICRNMHAWLRQDHKNVCVVHCMDGRAASAVAVCSFLCFC 480
Query: 132 NISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGS-IKINNKPLFLHHVI 190
+ ++A+ A+ F+MKR P PS +RY+ Y +++ I ++KP+ + V+
Sbjct: 481 RLFSTAEAAVYMFSMKR-----CPPGIWPSHKRYIEYMCDMVAEEPITPHSKPILVRAVV 535
Query: 191 MHGIPNF-ESKGGCRPFLRIYQAMQPV-YTSGIYNIPGDSQTSVCITIEP-GLLLKGDIL 247
M +P F + + GCRPF +Y + V TS Y+ D + + P G+ ++GD+L
Sbjct: 536 MTPVPLFSKQRSGCRPFCEVYVGDERVASTSQEYDKMRDFKIEDGKAVIPLGVTVQGDVL 595
Query: 248 LKCYHKKF-------RSPARDVIFRVQFHTCAI--HDLGVVFGKEDLDDAFKDDRFPEYG 298
+ YH + A +F++QFHT + + V F K DLD +++P+
Sbjct: 596 IVIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKYPDLF 655
Query: 299 KVEFVFSYGP 308
+V P
Sbjct: 656 QVNLEVEVEP 665
>sp|P97874|GAK_RAT CYCLIN G-ASSOCIATED KINASE
pir||T31096 cyclin G-associated kinase GAK - rat
dbj|BAA18911.1| (D38560) cyclinG-associated kinase [Rattus norvegicus]
Length = 1305
Score = 145 bits (363), Expect = 3e-33
Identities = 159/653 (24%), Positives = 255/653 (38%), Gaps = 88/653 (13%)
Query: 12 ELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSERRPDITKLH 71
+LD+ Y+T RI +SFP+ E ++N+ +V L +KH G+Y ++NLS R +K H
Sbjct: 405 DLDISYITSRIAVMSFPAEGVESAIKNNIEDVRLFLDAKHPGHYAVYNLSPRIYRASKFH 464
Query: 72 AKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYS 131
+V E GW P L + ++C++M WL D NV V+H R V + A++ +
Sbjct: 465 NRVTECGWAVRRAPHLHSLYTLCRSMHAWLREDHRNVCVVHCMDGRAASAVAVCAFLCFC 524
Query: 132 NISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGS-IKINNKPLFLHHVI 190
+ ++A+ A+ F+MKR P PS +RY+ Y +++ I ++KP+ + V+
Sbjct: 525 RLFSTAEAAVYMFSMKR-----CPPGIWPSHKRYIEYVCDMVAEEPITPHSKPMLVKSVV 579
Query: 191 MHGIPNF-ESKGGCRPFLRIYQAMQPV-YTSGIYNIPGDSQTSVCITIEP-GLLLKGDIL 247
M +P F + + GCRPF +Y + V TS Y+ + + + P G+ ++GD+L
Sbjct: 580 MTPVPLFSKQRNGCRPFCEVYVGEERVTTTSQEYDRMKEFKIEDGKAVIPLGITVQGDVL 639
Query: 248 LKCYHKKF-------RSPARDVIFRVQFHTCAI--HDLGVVFGKEDLDDAFKDDRFPEYG 298
YH + A +F++QFHT + + V F K DLD +++P+
Sbjct: 640 TIIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKYPDLF 699
Query: 299 KVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLI----RWDSYDNFSGHRDDGMEEVV 354
+V P + + P + +P I R + D S +
Sbjct: 700 QVNLEVEVEP---RDRPSRDVPPWENTSLRGLNPKILFSNREEQQDILSKFGKPELPRQP 756
Query: 355 GHT--QGPLDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTAS 412
G T GS A++ + DS S S NH HTL + T
Sbjct: 757 GSTAQYDAEAGSPEAEITESDSPQSS-----------STDTNHFLHTLDWQEEKDPETG- 804
Query: 413 TKTDKTDEPVPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSA 472
D P S + D + E K GA T L +
Sbjct: 805 -----VDNTSPKESQSNLIADGDGSEVSDEEEASCPSEERKPGAGEDTPRLAAGTRQQDL 859
Query: 473 VPSSGRHVVPAQ------------VHVNG---------GALASERETDILDDELPNQDGH 511
+ G P + +H G + TD+L L D
Sbjct: 860 IFDVGMLAAPQEPVQPEEGVDLLGLHSEGDLRPAAPLQASGVQSSNTDLLSSLLEPSDAS 919
Query: 512 SAGSMGTL------------SSLDGVTNTSEGGYPEALSP-----LTNGLDKSYPMEPMV 554
G G L SL GV + +G P+ + P L + D +P +
Sbjct: 920 QVGPPGDLLGGETPLLLASPVSLLGVQSNLQGKVPDTVDPFDQFLLPSSSDTQPCSKPDL 979
Query: 555 NGGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAWPQPVTTS 607
G +S + + + H+AP PS S + G PA P V S
Sbjct: 980 FGEFLNSDSVASSTAFPSTHSAP-PPSCS-----TAFLHLGDLPAEPNKVIAS 1026
>gb|AAB96620.1| (AF017185) protein tyrosine phosphatase and tensin homolog/mutated
in multiple advanced cancers protein [Rattus norvegicus]
Length = 403
Score = 144 bits (359), Expect = 1e-32
Identities = 89/267 (33%), Positives = 141/267 (52%), Gaps = 5/267 (1%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R ED +LDL Y+ IIA+ FP+ E +R+N+ +V + L SKH +Y ++NL +ER
Sbjct: 15 RYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAER 74
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D K + +V ++ + D + P LE I C+ +D WL+ D ++V +H K +GR GV+
Sbjct: 75 HYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVM 134
Query: 124 IAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKINNKP 183
I AY+ + A +ALD + R + K V I PSQRRYV+Y+S LL +
Sbjct: 135 ICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTI--PSQRRYVYYYSYLLKNHLDYRPVA 192
Query: 184 LFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLK 243
L H ++ IP F S G C P + Q +Y+S + + +P L +
Sbjct: 193 LLFHKMMFETIPMF-SGGTCNPQFVVCQLKVKIYSSNSGPTRREDKLMYFEFPQP-LPVC 250
Query: 244 GDILLKCYHKKFRSPARDVIFRVQFHT 270
GDI ++ +HK+ + +D +F +T
Sbjct: 251 GDIKVEFFHKQNKMLKKDKMFHFWVNT 277
>ref|NP_032986.1| phosphatase and tensin homolog [Mus musculus]
sp|O08586|PTEN_MOUSE PROTEIN-TYROSINE PHOSPHATASE PTEN (MUTATED IN MULTIPLE ADVANCED
CANCERS 1)
gb|AAC53118.1| (U92437) MMAC1 [Mus musculus]
Length = 403
Score = 143 bits (358), Expect = 1e-32
Identities = 89/267 (33%), Positives = 141/267 (52%), Gaps = 5/267 (1%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R ED +LDL Y+ IIA+ FP+ E +R+N+ +V + L SKH +Y ++NL +ER
Sbjct: 15 RYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAER 74
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D K + +V ++ + D + P LE I C+ +D WL+ D ++V +H K +GR GV+
Sbjct: 75 HYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVM 134
Query: 124 IAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKINNKP 183
I AY+ + A +ALD + R + K V I PSQRRYV+Y+S LL +
Sbjct: 135 ICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTI--PSQRRYVYYYSYLLKNHLDYRPVA 192
Query: 184 LFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLK 243
L H ++ IP F S G C P + Q +Y+S + + +P L +
Sbjct: 193 LLFHKMMFETIPMF-SGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQP-LPVC 250
Query: 244 GDILLKCYHKKFRSPARDVIFRVQFHT 270
GDI ++ +HK+ + +D +F +T
Sbjct: 251 GDIKVEFFHKQNKMLKKDKMFHFWVNT 277
>ref|NP_000305.1| phosphatase and tensin homolog (mutated in multiple advanced
cancers 1); multiple hamartoma (Cowden syndrome);
Bannayan-Zonana syndrome [Homo sapiens]
ref|XP_005867.1| phosphatase and tensin homolog (mutated in multiple advanced
cancers 1) [Homo sapiens]
sp|O00633|PTEN_HUMAN PROTEIN-TYROSINE PHOSPHATASE PTEN (MUTATED IN MULTIPLE ADVANCED
CANCERS 1)
gb|AAC48709.1| (U92435) MMAC1 [Canis familiaris]
gb|AAC51182.1| (U92436) MMAC1 [Homo sapiens]
gb|AAC51183.1| (U93051) putative protein tyrosine phosphatase [Homo sapiens]
gb|AAB66902.1| (U96180) protein tyrosine phosphatase [Homo sapiens]
gb|AAC08699.1| (AF000734) putative protein tyrosine phosphatase [Homo sapiens]
gb|AAD13528.1| (AF067844) PTEN [Homo sapiens]
gb|AAD38372.1| (AF143315) PTEN [Homo sapiens]
Length = 403
Score = 143 bits (358), Expect = 1e-32
Identities = 89/267 (33%), Positives = 141/267 (52%), Gaps = 5/267 (1%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R ED +LDL Y+ IIA+ FP+ E +R+N+ +V + L SKH +Y ++NL +ER
Sbjct: 15 RYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAER 74
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D K + +V ++ + D + P LE I C+ +D WL+ D ++V +H K +GR GV+
Sbjct: 75 HYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVM 134
Query: 124 IAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKINNKP 183
I AY+ + A +ALD + R + K V I PSQRRYV+Y+S LL +
Sbjct: 135 ICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTI--PSQRRYVYYYSYLLKNHLDYRPVA 192
Query: 184 LFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLK 243
L H ++ IP F S G C P + Q +Y+S + + +P L +
Sbjct: 193 LLFHKMMFETIPMF-SGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQP-LPVC 250
Query: 244 GDILLKCYHKKFRSPARDVIFRVQFHT 270
GDI ++ +HK+ + +D +F +T
Sbjct: 251 GDIKVEFFHKQNKMLKKDKMFHFWVNT 277
>gb|AAD46165.1|AF144732_1 (AF144732) protein/lipid phosphatase Pten [Xenopus laevis]
Length = 402
Score = 143 bits (357), Expect = 2e-32
Identities = 95/299 (31%), Positives = 153/299 (50%), Gaps = 16/299 (5%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R ED +LDL Y+ IIA+ FP+ E +R+N+ +V + L SKH +Y ++NL +ER
Sbjct: 15 RYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAER 74
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D K +V ++ + D + P LE I C+ +D L ++ NV +H K +GR GV+
Sbjct: 75 HYDTNKFSCRVAQYPFEDHNPPQLELIKPFCEDLDQLL-SENENVAAIHCKAGKGRTGVM 133
Query: 124 IAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKINNKP 183
I AY+ + A +ALD + R + K V I PSQRRYV+Y+S LL S++ P
Sbjct: 134 ICAYLLHRGKFPRAQEALDFYGEVRTRDKKGVTI--PSQRRYVYYYSYLLKNSLEYRPVP 191
Query: 184 LFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLK 243
L H + IP F S C P +YQ ++TS P ++ + L +
Sbjct: 192 LLFHKIEFETIPMF-SGSTCNPQFVVYQLKVKIFTSTAG--PKRAEKLMYFDFPQPLPVC 248
Query: 244 GDILLKCYHKKFRSPARDVIFRVQFHTCAIH---------DLGVVFGKEDLDDAFKDDR 293
GDI ++ +HK+ + ++ +F +T I + G + G+++LD + +R
Sbjct: 249 GDIKVEFFHKQNKVMKKEKMFHFWVNTFFIPGPEEYSEKVENGTLVGEQELDGIYSTER 307
>gb|AAF23236.1|AF201905_1 (AF201905) phosphatase and tensin homolog [Drosophila melanogaster]
Length = 506
Score = 138 bits (345), Expect = 4e-31
Identities = 99/318 (31%), Positives = 153/318 (47%), Gaps = 23/318 (7%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEEN-FRSNLREVAQMLKSKHGGNYLLFNL-SE 62
R E +LDL Y+ + IIA+ +P+ E FR+ L +V ++L+ H +Y ++NL SE
Sbjct: 22 RYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSE 81
Query: 63 RRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGV 122
R D+ K +V + + D + P +E I C +D WL D NVV +H K +GR G
Sbjct: 82 RSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGT 141
Query: 123 VIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKINNK 182
+I AY+ +S I SAD+AL + KR + K V I PSQRRYV YFS L+ S+ +
Sbjct: 142 MICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTI--PSQRRYVQYFSKLVCSSVPYSKV 199
Query: 183 PLFLHHVIMHGIPNFESKG--GCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL 240
L + + ++ G C + A + + +P D Q S +TI+P +
Sbjct: 200 SLNVCEIRFSESSCVQNLGMVECSISVLHDSATENAKPDRLKTLPIDFQKSFVLTIKPSI 259
Query: 241 LLKGDILLKCYHKKFRSPAR-------DVIFRVQFHTC----AIHDLGVVFGKEDLDDAF 289
+ GD+ + K SP + + F + C ++ K ++DD
Sbjct: 260 PVSGDVKFELTKK---SPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSEIDDVH 316
Query: 290 KDD---RFPEYGKVEFVF 304
KD RF E K+ VF
Sbjct: 317 KDSEHKRFSEEFKISIVF 334
>gb|AAF08382.1|AF144232_1 (AF144232) phosphatase PTEN [Drosophila melanogaster]
gb|AAF52888.1| (AE003628) Pten gene product [alt 3] [Drosophila melanogaster]
Length = 514
Score = 138 bits (345), Expect = 4e-31
Identities = 99/318 (31%), Positives = 153/318 (47%), Gaps = 23/318 (7%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEEN-FRSNLREVAQMLKSKHGGNYLLFNL-SE 62
R E +LDL Y+ + IIA+ +P+ E FR+ L +V ++L+ H +Y ++NL SE
Sbjct: 22 RYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSE 81
Query: 63 RRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGV 122
R D+ K +V + + D + P +E I C +D WL D NVV +H K +GR G
Sbjct: 82 RSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGT 141
Query: 123 VIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKINNK 182
+I AY+ +S I SAD+AL + KR + K V I PSQRRYV YFS L+ S+ +
Sbjct: 142 MICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTI--PSQRRYVQYFSKLVCSSVPYSKV 199
Query: 183 PLFLHHVIMHGIPNFESKG--GCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL 240
L + + ++ G C + A + + +P D Q S +TI+P +
Sbjct: 200 SLNVCEIRFSESSCVQNLGMVECSISVLHDSATENAKPDRLKTLPIDFQKSFVLTIKPSI 259
Query: 241 LLKGDILLKCYHKKFRSPAR-------DVIFRVQFHTC----AIHDLGVVFGKEDLDDAF 289
+ GD+ + K SP + + F + C ++ K ++DD
Sbjct: 260 PVSGDVKFELTKK---SPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSEIDDVH 316
Query: 290 KDD---RFPEYGKVEFVF 304
KD RF E K+ VF
Sbjct: 317 KDSEHKRFSEEFKISIVF 334
>gb|AAD45364.1|AF161259_1 (AF161259) PTEN3 [Drosophila melanogaster]
gb|AAF23235.1|AF201904_1 (AF201904) phosphatase and tensin homolog [Drosophila melanogaster]
gb|AAF52889.1| (AE003628) Pten gene product [alt 2] [Drosophila melanogaster]
gb|AAF52887.2| (AE003628) Pten gene product [alt 1] [Drosophila melanogaster]
Length = 509
Score = 138 bits (345), Expect = 4e-31
Identities = 99/318 (31%), Positives = 153/318 (47%), Gaps = 23/318 (7%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEEN-FRSNLREVAQMLKSKHGGNYLLFNL-SE 62
R E +LDL Y+ + IIA+ +P+ E FR+ L +V ++L+ H +Y ++NL SE
Sbjct: 22 RYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSE 81
Query: 63 RRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGV 122
R D+ K +V + + D + P +E I C +D WL D NVV +H K +GR G
Sbjct: 82 RSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGT 141
Query: 123 VIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKINNK 182
+I AY+ +S I SAD+AL + KR + K V I PSQRRYV YFS L+ S+ +
Sbjct: 142 MICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTI--PSQRRYVQYFSKLVCSSVPYSKV 199
Query: 183 PLFLHHVIMHGIPNFESKG--GCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL 240
L + + ++ G C + A + + +P D Q S +TI+P +
Sbjct: 200 SLNVCEIRFSESSCVQNLGMVECSISVLHDSATENAKPDRLKTLPIDFQKSFVLTIKPSI 259
Query: 241 LLKGDILLKCYHKKFRSPAR-------DVIFRVQFHTC----AIHDLGVVFGKEDLDDAF 289
+ GD+ + K SP + + F + C ++ K ++DD
Sbjct: 260 PVSGDVKFELTKK---SPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSEIDDVH 316
Query: 290 KDD---RFPEYGKVEFVF 304
KD RF E K+ VF
Sbjct: 317 KDSEHKRFSEEFKISIVF 334
>gb|AAD45363.1|AF161258_1 (AF161258) PTEN2 [Drosophila melanogaster]
Length = 511
Score = 138 bits (345), Expect = 4e-31
Identities = 99/318 (31%), Positives = 153/318 (47%), Gaps = 23/318 (7%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEEN-FRSNLREVAQMLKSKHGGNYLLFNL-SE 62
R E +LDL Y+ + IIA+ +P+ E FR+ L +V ++L+ H +Y ++NL SE
Sbjct: 22 RYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSE 81
Query: 63 RRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGV 122
R D+ K +V + + D + P +E I C +D WL D NVV +H K +GR G
Sbjct: 82 RSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGT 141
Query: 123 VIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKINNK 182
+I AY+ +S I SAD+AL + KR + K V I PSQRRYV YFS L+ S+ +
Sbjct: 142 MICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTI--PSQRRYVQYFSKLVCSSVPYSKV 199
Query: 183 PLFLHHVIMHGIPNFESKG--GCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL 240
L + + ++ G C + A + + +P D Q S +TI+P +
Sbjct: 200 SLNVCEIRFSESSCVQNLGMVECSISVLHDSATENAKPDRLKTLPIDFQKSFVLTIKPSI 259
Query: 241 LLKGDILLKCYHKKFRSPAR-------DVIFRVQFHTC----AIHDLGVVFGKEDLDDAF 289
+ GD+ + K SP + + F + C ++ K ++DD
Sbjct: 260 PVSGDVKFELTKK---SPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSEIDDVH 316
Query: 290 KDD---RFPEYGKVEFVF 304
KD RF E K+ VF
Sbjct: 317 KDSEHKRFSEEFKISIVF 334
>gb|AAD45362.1|AF161257_1 (AF161257) PTEN1 [Drosophila melanogaster]
Length = 418
Score = 138 bits (345), Expect = 4e-31
Identities = 99/318 (31%), Positives = 153/318 (47%), Gaps = 23/318 (7%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEEN-FRSNLREVAQMLKSKHGGNYLLFNL-SE 62
R E +LDL Y+ + IIA+ +P+ E FR+ L +V ++L+ H +Y ++NL SE
Sbjct: 22 RYKEKGYDLDLTYINDNIIAMGYPAPDKLEGLFRNRLEDVFKLLEENHAQHYKIYNLCSE 81
Query: 63 RRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGV 122
R D+ K +V + + D + P +E I C +D WL D NVV +H K +GR G
Sbjct: 82 RSYDVAKFRGRVAVYPFDDHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGT 141
Query: 123 VIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKINNK 182
+I AY+ +S I SAD+AL + KR + K V I PSQRRYV YFS L+ S+ +
Sbjct: 142 MICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTI--PSQRRYVQYFSKLVCSSVPYSKV 199
Query: 183 PLFLHHVIMHGIPNFESKG--GCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL 240
L + + ++ G C + A + + +P D Q S +TI+P +
Sbjct: 200 SLNVCEIRFSESSCVQNLGMVECSISVLHDSATENAKPDRLKTLPIDFQKSFVLTIKPSI 259
Query: 241 LLKGDILLKCYHKKFRSPAR-------DVIFRVQFHTC----AIHDLGVVFGKEDLDDAF 289
+ GD+ + K SP + + F + C ++ K ++DD
Sbjct: 260 PVSGDVKFELTKK---SPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSEIDDVH 316
Query: 290 KDD---RFPEYGKVEFVF 304
KD RF E K+ VF
Sbjct: 317 KDSEHKRFSEEFKISIVF 334
>gb|AAC52017.1| (AF019083) phosphatase and tensin homolog 2 [Homo sapiens]
Length = 403
Score = 138 bits (344), Expect = 5e-31
Identities = 87/267 (32%), Positives = 140/267 (51%), Gaps = 5/267 (1%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R ED +LDL Y+ IIA+ FP+ E +R+N+ +V + L SKH +Y + NL +ER
Sbjct: 15 RYQEDGFDLDLTYIYLNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIHNLCAER 74
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D K + +V ++ + D + P LE I C+ +D WL+ D ++V +H K +GR G++
Sbjct: 75 HYDTAKSNYRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGIM 134
Query: 124 IAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKINNKP 183
I AY+ + A +ALD + R + K V I PSQRRYV+Y+S L+ +
Sbjct: 135 ICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTI--PSQRRYVYYYSYLVKNHLDYRPVA 192
Query: 184 LFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLK 243
L H ++ IP F S G C P + Q +Y+S + + +P L +
Sbjct: 193 LLFHKMMFETIPMF-SGGTCNPQFVVCQLKVKIYSSNSGPTRWEDKFMYFEFPQP-LPVC 250
Query: 244 GDILLKCYHKKFRSPARDVIFRVQFHT 270
GDI ++ +HK+ + +D +F +T
Sbjct: 251 GDIKVEFFHKQNKMLKKDKMFHFWVNT 277
>gb|AAB70558.1| (AF017999) putative protein tyrosine phosphatase homologue [Homo
sapiens]
Length = 338
Score = 136 bits (340), Expect = 2e-30
Identities = 87/267 (32%), Positives = 140/267 (51%), Gaps = 5/267 (1%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R ED +LDL Y+ IIA+ FP+ E +R+N+ +V + L SKH +Y + NL +ER
Sbjct: 15 RYQEDGFDLDLTYIYLNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIHNLCAER 74
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D K + +V ++ + D + P LE I C+ +D WL+ D ++V +H K +GR G++
Sbjct: 75 HYDTAKSNYRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGIM 134
Query: 124 IAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKINNKP 183
I AY+ + A +ALD + R + K V I PSQRRYV+Y+S L+ +
Sbjct: 135 IYAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTI--PSQRRYVYYYSYLVKNHLDYRPVA 192
Query: 184 LFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLK 243
L H ++ IP F S G C P + Q +Y+S + + +P L +
Sbjct: 193 LLFHKMMFETIPMF-SGGTCNPQFVVCQLKVKMYSSNSGPTRWEDKFMYFEFPQP-LPVC 250
Query: 244 GDILLKCYHKKFRSPARDVIFRVQFHT 270
GDI ++ +HK+ + +D +F +T
Sbjct: 251 GDIKVEFFHKQNKMLKKDKMFHFWVNT 277
>emb|CAB90528.1| (AL163201) tensin, putative protein-tyrosine phosphatase, EC
3.1.3.48 [Homo sapiens]
Length = 551
Score = 124 bits (309), Expect = 7e-27
Identities = 89/312 (28%), Positives = 152/312 (48%), Gaps = 15/312 (4%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R D +LDL YVTERIIA+SFPS+ + +R+ ++EV + L KH +Y ++NL SER
Sbjct: 229 RYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSER 288
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D H +V+ D + P L ++ K ++ W+ D N+V +H KG R G +
Sbjct: 289 AYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTM 348
Query: 124 IAAYMHYSNISASADQALDRFAMKR---FYEDKIVPIGQPSQRRYVHYFSGL--LSGSIK 178
+ A++ S I ++A ++L F +R + +K + PSQ+RYV YF+ + L
Sbjct: 349 VCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVKTPSQKRYVAYFAQVKHLYNWNL 408
Query: 179 INNKPLFLHHVIMHGIPNFESKGGCRPFLR---IYQAMQPVYTSGIYNIPGDSQTSVCIT 235
+ LF+ H I++ IP + + + ++ + S + NI D + I
Sbjct: 409 PPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTD---KILID 465
Query: 236 IEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDR-- 293
+ GL L D+ ++ ++ + + F HT I + + K +LD+ K
Sbjct: 466 VFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARR 525
Query: 294 -FPEYGKVEFVF 304
+P VE +F
Sbjct: 526 IYPSDFAVEILF 537
>sp|Q27974|AUXI_BOVIN AUXILIN
pir||S68983 auxilin - bovine
gb|AAA79037.1| (U09237) auxilin [Bos taurus]
Length = 910
Score = 122 bits (304), Expect = 3e-26
Identities = 86/303 (28%), Positives = 148/303 (48%), Gaps = 20/303 (6%)
Query: 12 ELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSERRPDITKLH 71
+LD YVT RII +SFP + + FR+ + ++ L S+H +Y ++NLS + K H
Sbjct: 60 DLDFTYVTSRIIVMSFPLDSVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFH 119
Query: 72 AKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYS 131
++V E WP P+L + ++C+ M WL +P NV V+H R +++ A +
Sbjct: 120 SRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFC 179
Query: 132 NISASADQALDRFAMKRFYEDKIVPIG-QPSQRRYVHYFSGLLSGS-IKINNKPLFLHHV 189
N+ ++ A+ KR IG PS RRY+ Y LL+ + + KPL + +
Sbjct: 180 NLYSTPGPAVRLLYAKR------PGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSI 233
Query: 190 IMHGIPNF-ESKGGCRPFLRIYQAMQPVYT--SGIYNIPGDSQTSVCITIEPGLLLKGDI 246
+ +P F + + GCRP+ + +YT + + I I + ++GD+
Sbjct: 234 TVSPVPFFNKQRNGCRPYCDVLIGETKIYTTCADFERMKEYRVQDGKIFIPLSITVQGDV 293
Query: 247 LLKCYHKKFRSPAR-------DVIFRVQFHTCAIH-DLGVV-FGKEDLDDAFKDDRFPEY 297
++ YH + +R IF++QFHT I D V+ F K +LD +++P+
Sbjct: 294 VVSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQL 353
Query: 298 GKV 300
+V
Sbjct: 354 FQV 356
>ref|NP_037447.1| transmembrane phosphatase with tensin homology; tensin, putative
protein-tyrosine phosphatase [Homo sapiens]
sp|P56180|TPTE_HUMAN PUTATIVE PROTEIN-TYROSINE PHOSPHATASE TPTE
gb|AAC34574.1| (AF007118) putative tyrosine phosphatase [Homo sapiens]
Length = 551
Score = 122 bits (302), Expect = 5e-26
Identities = 88/312 (28%), Positives = 151/312 (48%), Gaps = 15/312 (4%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R D +LDL YVTERIIA+SFPS+ + +R+ ++EV + L KH +Y ++NL SER
Sbjct: 229 RYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSER 288
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D H +V+ D + P L ++ K ++ W+ D N+V +H KG R G +
Sbjct: 289 AYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTM 348
Query: 124 IAAYMHYSNISASADQALDRFAMKR---FYEDKIVPIGQPSQRRYVHYFSGL--LSGSIK 178
+ A++ S I ++A ++L F +R + +K + PSQ+RYV YF+ + L
Sbjct: 349 VCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNL 408
Query: 179 INNKPLFLHHVIMHGIPNFESKGGCRPFLR---IYQAMQPVYTSGIYNIPGDSQTSVCIT 235
+ LF+ H I++ IP + + + ++ + S + NI D + I
Sbjct: 409 PPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTD---KILID 465
Query: 236 IEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDR-- 293
+ G L D+ ++ ++ + + F HT I + + K +LD+ K
Sbjct: 466 VFDGPPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARR 525
Query: 294 -FPEYGKVEFVF 304
+P VE +F
Sbjct: 526 IYPSDFAVEILF 537
>ref|NP_055602.1| KIAA0473 gene product [Homo sapiens]
dbj|BAA32318.1| (AB007942) KIAA0473 protein [Homo sapiens]
Length = 913
Score = 120 bits (299), Expect = 1e-25
Identities = 86/303 (28%), Positives = 147/303 (48%), Gaps = 20/303 (6%)
Query: 12 ELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSERRPDITKLH 71
+LD YVT RII +SFP + FR+ + ++ L S+H +Y ++NLS + K H
Sbjct: 63 DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFH 122
Query: 72 AKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYS 131
++V E WP P+L + ++C+ M WL +P NV V+H R +++ A +
Sbjct: 123 SRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFC 182
Query: 132 NISASADQALDRFAMKRFYEDKIVPIG-QPSQRRYVHYFSGLLSGS-IKINNKPLFLHHV 189
N+ ++ A+ KR IG PS RRY+ Y LL+ + + KPL + +
Sbjct: 183 NLYSTPGPAIRLLYAKR------PGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSI 236
Query: 190 IMHGIPNF-ESKGGCRPFLRIYQAMQPVYT--SGIYNIPGDSQTSVCITIEPGLLLKGDI 246
+ IP F + + GCRP+ + +Y+ + + I I + ++GD+
Sbjct: 237 TVSPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDV 296
Query: 247 LLKCYHKKFRSPAR-------DVIFRVQFHTCAIH-DLGVV-FGKEDLDDAFKDDRFPEY 297
++ YH + +R IF++QFHT I D V+ F K +LD +++P+
Sbjct: 297 VVSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQL 356
Query: 298 GKV 300
+V
Sbjct: 357 FQV 359
>ref|XP_005775.1| similar to transmembrane phosphatase with tensin homology (H.
sapiens) [Homo sapiens]
Length = 344
Score = 118 bits (293), Expect = 5e-25
Identities = 68/199 (34%), Positives = 110/199 (55%), Gaps = 6/199 (3%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R D +LDL YVTERIIA+SFPS+ + +R+ ++EV + L KH +Y ++NL SER
Sbjct: 91 RYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSER 150
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D H +V+ D + P L ++ K ++ W+ D N+V +H KG R G +
Sbjct: 151 AYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTM 210
Query: 124 IAAYMHYSNISASADQALDRFAMKR---FYEDKIVPIGQPSQRRYVHYFSGL--LSGSIK 178
+ A++ S I ++A ++L F +R + +K + PSQ+RYV YF+ + L
Sbjct: 211 VCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNL 270
Query: 179 INNKPLFLHHVIMHGIPNF 197
+ LF+ H I++ IP +
Sbjct: 271 PPRRILFIKHFIIYSIPRY 289
>emb|CAA10315.1| (AJ131181) DAF-18 protein [Caenorhabditis elegans]
gb|AAD03420.1| (AF098286) DAF-18 [Caenorhabditis elegans]
gb|AAD21620.1| (AF126286) PTEN phosphatidylinositol 3' phosphatase homolog DAF-18
[Caenorhabditis elegans]
Length = 962
Score = 114 bits (282), Expect = 1e-23
Identities = 65/170 (38%), Positives = 94/170 (55%), Gaps = 4/170 (2%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHG-GNYLLFNL-SE 62
RT + +LD Y+T+RIIA+ +P+T E NFR++ + Q L +HG GN +FNL
Sbjct: 59 RTEYQNIDLDCAYITDRIIAIGYPATGIEANFRNSKVQTQQFLTRRHGKGNVKVFNLRGG 118
Query: 63 RRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGV 122
D V+ F D H P+LE + C+ WL AD +V+ +H K +GR GV
Sbjct: 119 YYYDADNFDGNVICFDMTDHHPPSLELMAPFCREAKEWLEADDKHVIAVHCKAGKGRTGV 178
Query: 123 VIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGL 172
+I A + Y N S Q LD +++ R +K V I PSQRRY++Y+ L
Sbjct: 179 MICALLIYINFYPSPRQILDYYSIIRTKNNKGVTI--PSQRRYIYYYHKL 226
>pir||T32574 hypothetical protein T07A9.6 - Caenorhabditis elegans
gb|AAB92004.1| (AF036706) contains similarity to Gallus gallus cardiac muscle
tensin (GB:M96625) [Caenorhabditis elegans]
Length = 965
Score = 114 bits (282), Expect = 1e-23
Identities = 65/170 (38%), Positives = 94/170 (55%), Gaps = 4/170 (2%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHG-GNYLLFNL-SE 62
RT + +LD Y+T+RIIA+ +P+T E NFR++ + Q L +HG GN +FNL
Sbjct: 59 RTEYQNIDLDCAYITDRIIAIGYPATGIEANFRNSKVQTQQFLTRRHGKGNVKVFNLRGG 118
Query: 63 RRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGV 122
D V+ F D H P+LE + C+ WL AD +V+ +H K +GR GV
Sbjct: 119 YYYDADNFDGNVICFDMTDHHPPSLELMAPFCREAKEWLEADDKHVIAVHCKAGKGRTGV 178
Query: 123 VIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGL 172
+I A + Y N S Q LD +++ R +K V I PSQRRY++Y+ L
Sbjct: 179 MICALLIYINFYPSPRQILDYYSIIRTKNNKGVTI--PSQRRYIYYYHKL 226
>dbj|BAB11013.1| (AB009054) contains similarity to protein-tyrosine
phosphatase~gene_id:MUL8.8 [Arabidopsis thaliana]
Length = 412
Score = 113 bits (279), Expect = 2e-23
Identities = 60/168 (35%), Positives = 104/168 (61%), Gaps = 5/168 (2%)
Query: 12 ELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLS-ERRPDITKL 70
+LD+ Y++++++A+SFP+ +R+ L +V +L +H +Y ++NL E D
Sbjct: 50 DLDMSYISDKLLAMSFPAERMRAVYRNPLWQVKSVLDMRHPDHYKVYNLCIEESYDPDNF 109
Query: 71 HAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHY 130
+ +V F + D H P+L+ I C+++ +WL+ DP N+ V+H +GR G++++AY+ Y
Sbjct: 110 YGRVERFPFDDNHVPSLKMIQLFCESVHSWLSLDPKNIAVVHCMAGKGRTGLMVSAYLVY 169
Query: 131 SNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIK 178
+ SA++AL+ +A +R + V I PSQRRYV Y+S LLS S K
Sbjct: 170 GGM--SAEEALEMYASRRTTNNNGVSI--PSQRRYVKYWSDLLSFSKK 213
>dbj|BAA99691.1| (AB025624) tyrosine phosphatase-like [Arabidopsis thaliana]
Length = 611
Score = 106 bits (263), Expect = 2e-21
Identities = 61/179 (34%), Positives = 96/179 (53%), Gaps = 11/179 (6%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENF--------RSNLREVAQMLKSKHGGNYL 56
R E +LDL Y+TE IIA+ FP+ F R+ + EV L+++H G Y
Sbjct: 146 RYQEGGFDLDLTYITENIIAMGFPAGDMSSGFFGYVEGFYRNQMEEVINFLETQHKGKYK 205
Query: 57 LFNL-SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKG 115
++NL SER D++ KV F + D + P + + S C++ +WL D NVVV+H K
Sbjct: 206 VYNLCSERLYDVSLFEGKVASFPFDDHNCPPIHLVTSFCQSAYSWLKEDIENVVVVHCKA 265
Query: 116 NRGRIGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLS 174
R G++I + + Y +A++ +D + KR + K + + PSQ RYV YF +L+
Sbjct: 266 GMARTGLMICSLLLYLKFFPTAEECMDFYNQKRCVDGKGLVL--PSQIRYVKYFERILT 322
>pir||T45864 probable tyrosine phosphatase - Arabidopsis thaliana
emb|CAB62119.1| (AL132978) putative tyrosine phosphatase [Arabidopsis thaliana]
Length = 628
Score = 101 bits (250), Expect = 6e-20
Identities = 58/174 (33%), Positives = 93/174 (53%), Gaps = 11/174 (6%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEEN--------FRSNLREVAQMLKSKHGGNYL 56
R E +LD+ Y+TE IIA+ FP+ +R+++ EV + ++ H Y
Sbjct: 190 RYQEGEFDLDMTYITENIIAMGFPAGDISSGLFGFFEGLYRNHMEEVIKFFETHHKDKYK 249
Query: 57 LFNL-SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKG 115
++NL SER D ++ KV F + D + P ++ I S C++ TWL D NVVV+H K
Sbjct: 250 VYNLCSERLYDASRFEGKVASFPFDDHNCPPIQLIPSFCQSAYTWLKEDIQNVVVVHCKA 309
Query: 116 NRGRIGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYF 169
R G++I + Y +A++A+D + KR + K + + PSQ RYV Y+
Sbjct: 310 GMARTGLMICCLLLYLKFFPTAEEAIDYYNQKRCLDGKALVL--PSQIRYVKYY 361
>gb|AAF23237.1|AF201906_1 (AF201906) phosphatase and tensin homolog [Drosophila melanogaster]
Length = 412
Score = 94.4 bits (231), Expect = 1e-17
Identities = 73/240 (30%), Positives = 109/240 (45%), Gaps = 21/240 (8%)
Query: 81 DLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQA 140
D + P +E I C +D WL D NVV +H K +GR G +I AY+ +S I SAD+A
Sbjct: 1 DHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGTMICAYLVFSGIKKSADEA 60
Query: 141 LDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKINNKPLFLHHVIMHGIPNFESK 200
L + KR + K V I PSQRRYV YFS L+ S+ + L + + ++
Sbjct: 61 LAWYDEKRTKDRKGVTI--PSQRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNL 118
Query: 201 G--GCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLKGDILLKCYHKKFRSP 258
G C + A + + +P D Q S +TI+P + + GD+ + K SP
Sbjct: 119 GMVECSISVLHDSATENAKPDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKK---SP 175
Query: 259 AR-------DVIFRVQFHTC----AIHDLGVVFGKEDLDDAFKDD---RFPEYGKVEFVF 304
+ + F + C ++ K ++DD KD RF E K+ VF
Sbjct: 176 DKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVF 235
>gb|AAF52168.1| (AE003607) CG1107 gene product [alt 1] [Drosophila melanogaster]
gb|AAF52169.1| (AE003607) CG1107 gene product [alt 2] [Drosophila melanogaster]
Length = 1165
Score = 78.8 bits (191), Expect = 5e-13
Identities = 78/309 (25%), Positives = 143/309 (46%), Gaps = 35/309 (11%)
Query: 3 VSRTMEDSC---ELDLVYVTERIIAVSFPSTANEENFRSN-LREVAQMLKSKHGGNYL-L 57
V +TM+ S +LD+ ++T RI+ + PS E +++N + +V L+S+ L +
Sbjct: 399 VMQTMQQSLARNDLDISHITSRILVMPCPSDGFESTYKTNNIEDVRLSLESRFVPQKLSI 458
Query: 58 FNLSERRPDITKLHAKVLE----FGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHN 113
+N +R + +E +G P H P L+ + ++ M +LNADP +VV++
Sbjct: 459 YNFGQRTEPRLPPPVRTVEAGSVYGCPQAHAPNLQGLFTVSADMYNFLNADPKSVVIVQT 518
Query: 114 KGNRG-RIGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGL 172
+ G VI A + Y+++ + A+ FA+KR + +PS+ RY++YF +
Sbjct: 519 GDSGGCTAATVICALLMYADLLREPEDAVQVFAVKRHTINL-----RPSEFRYLYYFGDI 573
Query: 173 LSGS-IKINNKPLFLHHVIMHGIPNF-ESKGGCRPFLRIY-------QAMQPVYTSGIYN 223
L + + + K L + +P +++ GCR ++ +Y +Q +Y
Sbjct: 574 LRPTPLLPHYKNTTLVSLSCQPVPRMTKARDGCRIYMEVYCNGNLLLSTLQDYEKMRLYQ 633
Query: 224 I-PGDSQTSVCITIEPGLLLKGDILLKCYH--KKFRSPARDVIFRVQFHTCAI--HDLGV 278
PG I + L GD+ + +H K P I + QF+T I + +
Sbjct: 634 AGPGK------IVLPINLTACGDVTVVLFHARKGMVRPQGLKICQFQFNTGFIPEPETLI 687
Query: 279 VFGKEDLDD 287
F +DLDD
Sbjct: 688 TFTNQDLDD 696
>gb|AAF50718.1| (AE003564) CG6062 gene product [Drosophila melanogaster]
Length = 261
Score = 76.5 bits (185), Expect = 2e-12
Identities = 49/142 (34%), Positives = 72/142 (50%), Gaps = 18/142 (12%)
Query: 1463 WYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHE 1522
WY+ ISR+ A+ +L+ + PGAF++R S S G Y L ++V SPP
Sbjct: 129 WYQAGISRDIAVEVLQSKSPGAFLVRKSSSKPGCYALTLRVPSPP-------------GP 175
Query: 1523 LVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIP---NRDPTDES 1579
+ +++I PRG K+KG E F SL AL+ HS++P LP L +P N + +
Sbjct: 176 KIANYIILRSPRGYKIKGFRKE--FSSLKALITHHSVMPELLPVPLAMPRPTNMSSSRRN 233
Query: 1580 KDSSGPANSTADLLKQGAACNV 1601
D +S LLK A N+
Sbjct: 234 LDDFDTYDSLQMLLKYLRAKNM 255
>dbj|BAB11454.1| (AB010070) gb|AAD23008.1~gene_id:MBK20.21~similar to unknown
protein [Arabidopsis thaliana]
Length = 1289
Score = 73.7 bits (178), Expect = 2e-11
Identities = 62/239 (25%), Positives = 116/239 (47%), Gaps = 21/239 (8%)
Query: 87 LEKICSICKAMDTWLNAD-PHNVVVLH-NKGNRGRIGVVIAAYMHYSNISASADQALDRF 144
LE I ++ ++WL+ + NV+++H +G + +++ + Y + L+
Sbjct: 66 LEMIHHFLRSSESWLSLEGQQNVLLMHCERGGWPVLAFMLSGLLLYRKQYHGEQKTLEMV 125
Query: 145 AMKRFYE--DKIVPIG-QPSQRRYVHYFSGLLSGSI-KINNKPLFLHHVIMHGIPNFESK 200
+ E + P+ QPSQ RY+ Y S GS ++ PL L +I+ +P+FE K
Sbjct: 126 HKQAPKELLHLLSPLNPQPSQLRYLQYISRRNLGSDWPPSDTPLLLDCLILRDLPHFEGK 185
Query: 201 GGCRPFLRIYQAMQPVYTSGIYNIPGDS-----------QTSVCITIEPGL--LLKGDIL 247
GCRP LR+Y P + +I S Q CI ++ + ++GD++
Sbjct: 186 KGCRPILRVY-GQDPKARTNRSSILLFSTLKTKKHTRLYQQEECILVKLDIQCRVQGDVV 244
Query: 248 LKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFK-DDRFPEYGKVEFVFS 305
L+C H + +++FR+ FHT + ++ ++++D + D+FP+ K E +FS
Sbjct: 245 LECIHLHDDLVSEEMVFRIMFHTAFVRANILMLQRDEMDILWDVKDQFPKEFKAEVLFS 303
>gb|AAF50725.1| (AE003564) CG13289 gene product [Drosophila melanogaster]
Length = 258
Score = 73.4 bits (177), Expect = 2e-11
Identities = 44/122 (36%), Positives = 63/122 (51%), Gaps = 17/122 (13%)
Query: 1463 WYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHE 1522
W++ I RE ++ L Q PGAF++R S + G + L+++V P P
Sbjct: 123 WFQAGIPREISLEALSRQSPGAFLVRQSSTKPGCFALSLRVPPPSPR------------- 169
Query: 1523 LVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDS 1582
V H+LI RG K+KG E F SL AL+ HS++P LP L +P R P+ S+ S
Sbjct: 170 -VAHYLILRTQRGYKIKGFTKE--FSSLKALITHHSVMPELLPVPLTLP-RPPSTRSQRS 225
Query: 1583 SG 1584
G
Sbjct: 226 QG 227
Database: nr
Posted date: Dec 10, 2000 7:21 PM
Number of letters in database: 188,047,558
Number of sequences in database: 594,795
Lambda K H
0.313 0.131 0.389
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 658387654
Number of Sequences: 594795
Number of extensions: 29229126
Number of successful extensions: 62978
Number of sequences better than 10.0: 274
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 188
Number of HSP's that attempted gapping in prelim test: 61585
Number of HSP's gapped (non-prelim): 943
length of query: 1735
length of database: 188,047,558
effective HSP length: 62
effective length of query: 1673
effective length of database: 151,170,268
effective search space: 252907858364
effective search space used: 252907858364
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 42 (21.9 bits)
S2: 78 (34.8 bits)
