The RBR (ring between ring domains)-type protein family: XAP



Annotations:Hepatitis B virus X-associated protein 4 (HBV associated factor 4), XAP3, Chromosome 20 open reading frame 18 [Homo sapines], ubiquitin conjugating enzyme 7 interacting protein 3, UbcM4-interacting protein 28, Protein kinase C-binding protein Beta15
Domain Architecture: N ----------|----UBQ----|------------|-ZnF-|--------|-----------------RBR------------------|--- C


Fasta-File of the Family-Members

Fasta-File of Family-Members with complete RBR motif - full lenght sequences

Alignments: - MView
- Clustal

Fasta-File of Family-Members with complete RBR motif - RBR region

Alignments: - MView
- Clustal
HMM Search: - HMM file
- HMM output file

Literature
PubMed: 16643902 The E3 ubiquitin ligase HOIL-1 induces the polyubiquitination and degradation of SOCS6 associated proteins.
FEBS Lett. 2006 May 15;580(11):2609-2614. Epub 2006 Apr 21.
PubMed: 16083853 Cytoplasmic tethering of a RING protein RBCK1 by its splice variant lacking the RING domain.
Biochem Biophys Res Commun. 2005 Sep 23;335(2):550-7.
PubMed: 12629548 Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2.
Nat Cell Biol. 2003 Apr;5(4):336-40.
PubMed: 9195957 The hepatitis B virus X-associated protein, XAP3, is a protein kinase C-binding protein.
J Biol Chem. 1997 Jun 27;272(26):16482-9.


Author: Birgit.Eisenhaber@imp.univie.ac.at on internet.
Last modified: 2nd June 2006