RID=1063614802-16550-552815.BLASTQ3, NP_497145 gi|17552400|ref|NP_497145_1| CREB-binding protein like family member (3A735) [Caenorhabditis elegans] BLASTP 2.2.6 [Apr-09-2003]

RID: 1063614802-16550-552815.BLASTQ3

Query= NP_497145 gi|17552400|ref|NP_497145_1| CREB-binding protein like family member (3A735) [Caenorhabditis elegans] (226 letters)

Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 1,523,846 sequences; 490,609,399 total letters

Distribution of 63 Blast Hits on the Query Sequence




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|17552400|ref|NP_497145.1|  CREB-binding protein like fami...   389   e-107
gi|17554044|ref|NP_499201.1|  CREB-binding protein like fami...   116   3e-25
gi|482238|pir||S41033  hypothetical protein K03H1.10 - Caeno...   116   3e-25
gi|17552402|ref|NP_497144.1|  CREB-binding protein like fami...   111   7e-24
gi|17552708|ref|NP_499161.1|  CBP/p300 homolog (cbp-1) [Caen...   108   7e-23
gi|17553334|ref|NP_499197.1|  CREB-binding protein like fami...   106   2e-22
gi|17552710|ref|NP_499160.1|  CBP/p300 homolog (cbp-1) [Caen...   103   3e-21
gi|2133462|pir||S60123  hypothetical protein R10E11.1 - Caen...   103   3e-21
gi|7494646|pir||T37269  hypothetical protein - Caenorhabditi...    99   6e-20
gi|547239|gb|AAB31182.1|  p300=transcription coactivator {N-...    90   4e-17
gi|31204369|ref|XP_311133.1|  ENSANGP00000004748 [Anopheles ...    82   9e-15
gi|28486616|ref|XP_283295.1|  similar to E1A-associated prot...    80   2e-14
gi|17551090|ref|NP_510006.1|  CREB-binding protein like fami...    78   9e-14
gi|31753089|gb|AAH53889.1|  Unknown (protein for IMAGE:61513...    77   2e-13
gi|27881767|gb|AAH44677.1|  Similar to CREB binding protein ...    77   2e-13
gi|2996629|gb|AAC08447.1|  CBP [Homo sapiens]                      77   2e-13
gi|4557557|ref|NP_001420.1|  E1A binding protein p300; E1A-b...    77   2e-13
gi|631119|pir||S39162  transcription coactivator CREB-bindin...    77   2e-13
gi|4758056|ref|NP_004371.1|  CREB binding protein [Homo sapi...    77   3e-13
gi|4321116|gb|AAC51331.2|  CREB-binding protein [Homo sapiens]     77   3e-13
gi|19547885|gb|AAL87531.1|  CREB-binding protein [Mus muscul...    77   3e-13
gi|21307831|gb|AAL54859.1|  CREB-binding protein [Aplysia ca...    76   5e-13
gi|737920|prf||1923401A  protein CBP                               74   2e-12
gi|1345703|sp|P45481|CBP_MOUSE  CREB-binding protein >gi|481...    74   2e-12
gi|20664269|pdb|1L3E|B  Chain B, Nmr Structures Of The Hif-1...    70   2e-11
gi|20664319|pdb|1L8C|A  Chain A, Structural Basis For Hif-1a...    67   2e-10
gi|7511830|pir||T13828  CREB-binding protein homolog - fruit...    67   2e-10
gi|24640865|ref|NP_524642.2|  nejire CG15319-PB [Drosophila ...    66   3e-10
gi|27663074|ref|XP_235502.1|  similar to E1A-associated prot...    65   7e-10
gi|27666550|ref|XP_235770.1|  similar to E1A-associated prot...    65   7e-10
gi|7487910|pir||T01055  hypothetical protein YUP8H12R.38 - A...    53   3e-06
gi|18412221|ref|NP_565197.1|  p300/CBP acetyltransferase-rel...    53   4e-06
gi|15230656|ref|NP_187904.1|  CREB-binding protein -related ...    51   2e-05
gi|21105780|gb|AAM34788.1|AF512558_2  HAC5 [Arabidopsis thal...    50   3e-05
gi|15219327|ref|NP_173115.1|  expressed protein [Arabidopsis...    50   3e-05
gi|7489105|pir||T02019  callus-associated protein - common t...    50   4e-05
gi|25518555|pir||E86302  hypothetical protein F17F16.8 [impo...    50   4e-05
gi|4139873|pdb|1KDX|A  Chain A, Kix Domain Of Mouse Cbp (Cre...    45   6e-04
gi|8778322|gb|AAF79331.1|AC002304_24  F14J16.27 [Arabidopsis...    36   0.51 
gi|21105784|gb|AAM34789.1|AF512560_1  HAC4 [Arabidopsis thal...    36   0.57 
gi|6056385|gb|AAF02849.1|AC009894_20  Unknown protein [Arabi...    36   0.58 
gi|18405622|ref|NP_564706.1|  CREB-binding protein -related ...    35   0.68 
Alignments
>gi|17552400|ref|NP_497145.1| CREB-binding protein like family member (3A735) [Caenorhabditis
           elegans]
 gi|7496696|pir||T33580 hypothetical protein C29F9.5 - Caenorhabditis elegans
 gi|3790687|gb|AAC68747.1| Hypothetical protein C29F9.5 [Caenorhabditis elegans]
          Length = 226

 Score =  389 bits (1000), Expect = e-107
 Identities = 209/226 (92%), Positives = 209/226 (92%)

Query: 1   MNTLISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKE 60
           MNTLISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKE
Sbjct: 1   MNTLISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKE 60

Query: 61  GPKCNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTPAEPKKPEHDQIWHL 120
           GPKCNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTPAEPKKPEHDQIWHL
Sbjct: 61  GPKCNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTPAEPKKPEHDQIWHL 120

Query: 121 EVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAELQIFDTAQKLEAYYHMA 180
           EVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAELQIFDTAQKLEAYYHMA
Sbjct: 121 EVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAELQIFDTAQKLEAYYHMA 180

Query: 181 REKVCRYQEGFPRRQKTXXXXXXXXXXXXXXXXXRLEGTSTDYQGS 226
           REKVCRYQEGFPRRQKT                 RLEGTSTDYQGS
Sbjct: 181 REKVCRYQEGFPRRQKTEEKDESDGSEKEDEADDRLEGTSTDYQGS 226
>gi|17554044|ref|NP_499201.1| CREB-binding protein like family member (36.7 kD) (3L15)
           [Caenorhabditis elegans]
 gi|25395947|pir||D88569 protein K03H1.10 [imported] - Caenorhabditis elegans
 gi|3877003|emb|CAA82940.1| Hypothetical protein K03H1.10 [Caenorhabditis elegans]
 gi|3878179|emb|CAA82665.1| Hypothetical protein K03H1.10 [Caenorhabditis elegans]
          Length = 322

 Score =  116 bits (290), Expect = 3e-25
 Identities = 73/236 (30%), Positives = 110/236 (46%), Gaps = 44/236 (18%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           L+ +QL LLLHAH+C  RD +  E A +N+P PH  C++  C  MKEVL HMT+C  G  
Sbjct: 13  LVQQQLVLLLHAHKCSLRDKENNEFAARNQPLPHTTCRLPHCPTMKEVLIHMTNCNVGRL 72

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTP----------------- 106
           C+  HCASSR I++HWK C  E+CPVC P+   R  P   + P                 
Sbjct: 73  CHFAHCASSRQIIAHWKNCSREDCPVCTPLKRARDVPLIFSLPHLANLIGTKGNSYGSAD 132

Query: 107 -------------------------AEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSN 141
                                      P  P   + WH +V    R+ ++ K+ K I   
Sbjct: 133 GEVVHQIGVSTMSAGRITNGNISNLPPPNVPVRTKEWHRQVTNDLRNHIVGKLVKAICP- 191

Query: 142 VKPGTLSEAQMDTWKEYSRSAELQIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
             P  +++ ++     Y+R  E ++F+TA   + YYH+  EK+   Q+    ++ +
Sbjct: 192 -APEMMNDIRLKDLNAYARKVEKEVFETAIDRKNYYHLLAEKIYEIQKELQEKKNS 246
>gi|482238|pir||S41033 hypothetical protein K03H1.10 - Caenorhabditis elegans  (fragment)
          Length = 316

 Score =  116 bits (290), Expect = 3e-25
 Identities = 73/236 (30%), Positives = 110/236 (46%), Gaps = 44/236 (18%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           L+ +QL LLLHAH+C  RD +  E A +N+P PH  C++  C  MKEVL HMT+C  G  
Sbjct: 7   LVQQQLVLLLHAHKCSLRDKENNEFAARNQPLPHTTCRLPHCPTMKEVLIHMTNCNVGRL 66

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTP----------------- 106
           C+  HCASSR I++HWK C  E+CPVC P+   R  P   + P                 
Sbjct: 67  CHFAHCASSRQIIAHWKNCSREDCPVCTPLKRARDVPLIFSLPHLANLIGTKGNSYGSAD 126

Query: 107 -------------------------AEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSN 141
                                      P  P   + WH +V    R+ ++ K+ K I   
Sbjct: 127 GEVVHQIGVSTMSAGRITNGNISNLPPPNVPVRTKEWHRQVTNDLRNHIVGKLVKAICP- 185

Query: 142 VKPGTLSEAQMDTWKEYSRSAELQIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
             P  +++ ++     Y+R  E ++F+TA   + YYH+  EK+   Q+    ++ +
Sbjct: 186 -APEMMNDIRLKDLNAYARKVEKEVFETAIDRKNYYHLLAEKIYEIQKELQEKKNS 240
>gi|17552402|ref|NP_497144.1| CREB-binding protein like family member (3A733) [Caenorhabditis
           elegans]
 gi|7496697|pir||T33579 hypothetical protein C29F9.6 - Caenorhabditis elegans
 gi|3790688|gb|AAC68748.1| Hypothetical protein C29F9.6 [Caenorhabditis elegans]
          Length = 228

 Score =  111 bits (278), Expect = 7e-24
 Identities = 73/195 (37%), Positives = 95/195 (48%), Gaps = 14/195 (7%)

Query: 40  CKIQDCVIMKEVLKHMTSCKEGPKCNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTA 99
           C +  C  MKEV+ HM +C  G +C S HC SSR ++ HW +C N ECP+C      +  
Sbjct: 38  CPVPQCSTMKEVIGHMMTCWNGFQCPSEHCTSSRMVIHHWTRCTNAECPICGAHRTAQNM 97

Query: 100 PPQDTTP----AEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTW 155
               T P     EP+ P   Q WH EVPKT R  +IE+I K IM  + P          W
Sbjct: 98  NALSTIPIVKDPEPRPPGTSQPWHSEVPKTDREAVIERISKHIM--LHPQRFEP----IW 151

Query: 156 --KEYSRSAELQIFDTAQKLEAYYHMAREKVCRYQEGFPR--RQKTXXXXXXXXXXXXXX 211
             KE +R+AELQIF+ A   + YY M  E+  R Q+  P    Q+               
Sbjct: 152 KIKEDARAAELQIFEAAGSRDEYYRMVEERAPREQDKAPEGPGQEAQKEEKGAGEEDPDE 211

Query: 212 XXXRLEGTSTDYQGS 226
               +EGTS D+QGS
Sbjct: 212 VFDHMEGTSKDFQGS 226
>gi|17552708|ref|NP_499161.1| CBP/p300 homolog (cbp-1) [Caenorhabditis elegans]
 gi|14530537|emb|CAA82353.2| C. elegans CBP-1 protein (corresponding sequence R10E11.1a)
           [Caenorhabditis elegans]
          Length = 2045

 Score =  108 bits (270), Expect = 7e-23
 Identities = 55/103 (53%), Positives = 70/103 (67%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +QL LLLHAH+C +R+ + R+ A KN+P PHA C +  C  MKEVL HMTSC  G  
Sbjct: 405 LIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTSCNVGRL 464

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTP 106
           C+  HCASSR I++HWK C  E+CPVCKP+   +  P Q + P
Sbjct: 465 CHFAHCASSRQIIAHWKNCSREDCPVCKPLKRIQDTPLQFSLP 507

 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 23/89 (25%), Positives = 46/89 (51%)

Query: 109 PKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAELQIFD 168
           P  P+  + WH +V K  R+ L+ K+ K I        +++ ++     Y+R  E ++F+
Sbjct: 578 PDMPDCTKEWHHQVTKDLRNHLVGKLVKAIFPEPNQEAMNDNRLKDLIAYARKVEKEMFE 637

Query: 169 TAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
           +A   E YYH+  EK+ + Q+    ++ +
Sbjct: 638 SANDREEYYHLLAEKIYKIQKELQEKKNS 666
>gi|17553334|ref|NP_499197.1| CREB-binding protein like family member (22.2 kD) (3L5)
           [Caenorhabditis elegans]
 gi|542476|pir||S42836 F40F12.7 protein - Caenorhabditis elegans
 gi|3877001|emb|CAA82938.1| Hypothetical protein F40F12.7 [Caenorhabditis elegans]
          Length = 199

 Score =  106 bits (265), Expect = 2e-22
 Identities = 51/103 (49%), Positives = 67/103 (65%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +Q  LLLHAH+C +R+ +  E A +N+  PHA C +  C  MKEVL HMT+C  G  
Sbjct: 13  LIQQQFVLLLHAHKCSQREKENNEFAARNQLLPHAACTLPHCSTMKEVLIHMTNCNVGRL 72

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTP 106
           C+  HCASSR I++HWK C  E+CPVCKP+   +  P Q + P
Sbjct: 73  CHFAHCASSRQIIAHWKDCSREDCPVCKPLKGIQDTPLQFSLP 115
>gi|17552710|ref|NP_499160.1| CBP/p300 homolog (cbp-1) [Caenorhabditis elegans]
 gi|20455476|sp|P34545|CBP1_CAEEL Protein cbp-1
 gi|25299632|pir||G88564 protein R10E11.1 [imported] - Caenorhabditis elegans
 gi|17645979|emb|CAD18875.1| C. elegans CBP-1 protein (corresponding sequence R10E11.1b)
           [Caenorhabditis elegans]
          Length = 2056

 Score =  103 bits (256), Expect = 3e-21
 Identities = 56/114 (49%), Positives = 71/114 (62%), Gaps = 11/114 (9%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEG-- 61
           LI +QL LLLHAH+C +R+ + R+ A KN+P PHA C +  C  MKEVL HMTSC  G  
Sbjct: 405 LIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTSCNVGRL 464

Query: 62  ---------PKCNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTP 106
                     KC+  HCASSR I++HWK C  E+CPVCKP+   +  P Q + P
Sbjct: 465 CHSDTTQTTKKCSVAHCASSRQIIAHWKNCSREDCPVCKPLKRIQDTPLQFSLP 518

 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 23/89 (25%), Positives = 46/89 (51%)

Query: 109 PKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAELQIFD 168
           P  P+  + WH +V K  R+ L+ K+ K I        +++ ++     Y+R  E ++F+
Sbjct: 589 PDMPDCTKEWHHQVTKDLRNHLVGKLVKAIFPEPNQEAMNDNRLKDLIAYARKVEKEMFE 648

Query: 169 TAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
           +A   E YYH+  EK+ + Q+    ++ +
Sbjct: 649 SANDREEYYHLLAEKIYKIQKELQEKKNS 677
>gi|2133462|pir||S60123 hypothetical protein R10E11.1 - Caenorhabditis elegans
          Length = 2027

 Score =  103 bits (256), Expect = 3e-21
 Identities = 56/114 (49%), Positives = 71/114 (62%), Gaps = 11/114 (9%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEG-- 61
           LI +QL LLLHAH+C +R+ + R+ A KN+P PHA C +  C  MKEVL HMTSC  G  
Sbjct: 405 LIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTSCNVGRL 464

Query: 62  ---------PKCNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTP 106
                     KC+  HCASSR I++HWK C  E+CPVCKP+   +  P Q + P
Sbjct: 465 CHSDTTQTTKKCSVAHCASSRQIIAHWKNCSREDCPVCKPLKRIQDTPLQFSLP 518

 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 23/89 (25%), Positives = 46/89 (51%)

Query: 109 PKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAELQIFD 168
           P  P+  + WH +V K  R+ L+ K+ K I        +++ ++     Y+R  E ++F+
Sbjct: 589 PDMPDCTKEWHHQVTKDLRNHLVGKLVKAIFPEPNQEAMNDNRLKDLIAYARKVEKEMFE 648

Query: 169 TAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
           +A   E YYH+  EK+ + Q+    ++ +
Sbjct: 649 SANDREEYYHLLAEKIYKIQKELQEKKNS 677
>gi|7494646|pir||T37269 hypothetical protein - Caenorhabditis elegans (fragment)
 gi|2665395|dbj|BAA23766.1| unnamed protein product [Caenorhabditis elegans]
          Length = 118

 Score = 99.0 bits (245), Expect = 6e-20
 Identities = 55/103 (53%), Positives = 70/103 (67%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +QL LLLHAH+C +R+ + R+ A KN+P PHA C +  C  MKEVL HMTSC  G  
Sbjct: 9   LIQQQLVLLLHAHKCSQREKENRDFAAKNQPPPHAACTLPHCSTMKEVLTHMTSCNVGRL 68

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTP 106
           C+  HCASSR I++HWK C  E+CPVCKP+   +  P Q + P
Sbjct: 69  CHFAHCASSRQIIAHWKNCSREDCPVCKPLKRIQDTPLQFSLP 111
>gi|547239|gb|AAB31182.1| p300=transcription coactivator {N-terminal} [mice, Peptide Partial,
           688 aa]
          Length = 688

 Score = 89.7 bits (221), Expect = 4e-17
 Identities = 42/90 (46%), Positives = 52/90 (57%), Gaps = 9/90 (10%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           +I +QL LLLHAH+C RR+    E  +         C +  C  MK VL HMT C+ G  
Sbjct: 338 VIQQQLVLLLHAHKCQRREQANGEVRQ---------CNLPHCRTMKNVLNHMTHCQSGKS 388

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPI 93
           C   HCASSR I+SHWK C   +CPVC P+
Sbjct: 389 CQVAHCASSRQIISHWKNCTRHDCPVCLPL 418

 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 23/93 (24%), Positives = 47/93 (50%)

Query: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164
           T A+P      + WH ++ +  R+ L+ K+ + I     P  L + +M+    Y+R  E 
Sbjct: 559 TAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG 618

Query: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
            ++++A     YYH+  EK+ + Q+    +++T
Sbjct: 619 DMYESANNRAEYYHLLAEKIYKIQKELEEKRRT 651
>gi|31204369|ref|XP_311133.1| ENSANGP00000004748 [Anopheles gambiae]
 gi|30178093|gb|EAA06516.2| ENSANGP00000004748 [Anopheles gambiae str. PEST]
          Length = 2572

 Score = 81.6 bits (200), Expect = 9e-15
 Identities = 50/108 (46%), Positives = 63/108 (58%), Gaps = 12/108 (11%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +QL LLLHAH+C RR        E   P+ + +C +  C  MKEVL HM SC  G  
Sbjct: 345 LIQQQLVLLLHAHKCQRR--------EAENPSGN-ICSLAHCRTMKEVLTHMQSCLLGKN 395

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTPAEPKK 111
           C   HC+SSR I++HWK C  ++CPVC P ++Q     QDT   EP K
Sbjct: 396 CPKTHCSSSRQIINHWKNCQRQDCPVCLP-LQQHHDKQQDTL--EPAK 440

 Score = 42.4 bits (98), Expect = 0.006
 Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 1/80 (1%)

Query: 118 WHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAELQIFDTAQKLEAYY 177
           WH  V    R+ L+ K+ + I  +  P  + + +M     Y++  E  +++ A     YY
Sbjct: 745 WHHSVTPDLRNHLVHKLVQAIFPSPDPSAMFDKRMYNLVAYAKKVEGDMYEMANSRSEYY 804

Query: 178 HMAREKVCRYQEGF-PRRQK 196
           H+  EK+ + Q+    +RQK
Sbjct: 805 HLLAEKIYKIQKELEEKRQK 824
>gi|28486616|ref|XP_283295.1| similar to E1A-associated protein p300 [Mus musculus]
 gi|29244384|ref|NP_808489.1| hypothetical protein A730011L11 [Mus musculus]
 gi|26335221|dbj|BAC31311.1| unnamed protein product [Mus musculus]
          Length = 714

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 43/90 (47%), Positives = 52/90 (57%), Gaps = 9/90 (10%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +QL LLLHAH+C RR+    E  +         C +  C  MK VL HMT C+ G  
Sbjct: 338 LIQQQLVLLLHAHKCQRREQANGEVRQ---------CNLPHCRTMKNVLNHMTHCQSGKS 388

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPI 93
           C   HCASSR I+SHWK C   +CPVC P+
Sbjct: 389 CQVAHCASSRQIISHWKNCTRHDCPVCLPL 418

 Score = 52.8 bits (125), Expect = 5e-06
 Identities = 23/93 (24%), Positives = 47/93 (50%)

Query: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164
           T A+P      + WH ++ +  R+ L+ K+ + I     P  L + +M+    Y+R  E 
Sbjct: 559 TAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG 618

Query: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
            ++++A     YYH+  EK+ + Q+    +++T
Sbjct: 619 DMYESANNRAEYYHLLAEKIYKIQKELEEKRRT 651
>gi|17551090|ref|NP_510006.1| CREB-binding protein like family member (XM605) [Caenorhabditis
           elegans]
 gi|7497672|pir||T20071 hypothetical protein C49F5.5 - Caenorhabditis elegans
 gi|3875065|emb|CAB03976.1| Hypothetical protein C49F5.5 [Caenorhabditis elegans]
          Length = 151

 Score = 78.2 bits (191), Expect = 9e-14
 Identities = 34/95 (35%), Positives = 53/95 (55%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           +I  QL LLLHA+ C +RD +  +AA   +PA H  C +  C + K  L H+  C  G  
Sbjct: 53  VIKEQLILLLHANVCTKRDRENYQAAINGQPARHPRCDLPSCGLFKYTLSHLNMCTNGSH 112

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRT 98
           C   +C +S+ ++ HW++C N  C +C P+   +T
Sbjct: 113 CLIDYCNTSKQLIKHWRECQNRACAICAPLRRLQT 147
>gi|31753089|gb|AAH53889.1| Unknown (protein for IMAGE:6151364) [Homo sapiens]
          Length = 1553

 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 43/90 (47%), Positives = 52/90 (57%), Gaps = 9/90 (10%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +QL LLLHAH+C RR+    E  +         C +  C  MK VL HMT C+ G  
Sbjct: 337 LIQQQLVLLLHAHKCQRREQANGEVRQ---------CNLPHCRTMKNVLNHMTHCQSGKS 387

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPI 93
           C   HCASSR I+SHWK C   +CPVC P+
Sbjct: 388 CQVAHCASSRQIISHWKNCTRHDCPVCLPL 417

 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 23/93 (24%), Positives = 47/93 (50%)

Query: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164
           T A+P      + WH ++ +  R+ L+ K+ + I     P  L + +M+    Y+R  E 
Sbjct: 558 TAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG 617

Query: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
            ++++A     YYH+  EK+ + Q+    +++T
Sbjct: 618 DMYESANNRAEYYHLLAEKIYKIQKELEEKRRT 650
>gi|27881767|gb|AAH44677.1| Similar to CREB binding protein (Rubinstein-Taybi syndrome)
           [Xenopus laevis]
          Length = 1047

 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 43/90 (47%), Positives = 52/90 (57%), Gaps = 9/90 (10%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +QL LLLHAH+C RR+    E  +         C +  C  MK VL HMT C+ G  
Sbjct: 350 LIQQQLVLLLHAHKCQRREQANGEMRD---------CSLPHCRTMKNVLNHMTHCQAGKA 400

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPI 93
           C   HCASSR I+SHWK C   +CPVC P+
Sbjct: 401 CQVAHCASSRQIISHWKNCTRHDCPVCLPL 430

 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 23/93 (24%), Positives = 45/93 (48%)

Query: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164
           T A P      + WH  V +  R+ L+ K+ + I     P  L + +M+    Y+R  E 
Sbjct: 568 TAAPPSSTGVRKAWHEHVTQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG 627

Query: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
            ++++A   + YYH   EK+ + Q+    ++++
Sbjct: 628 DMYESANSRDEYYHFLAEKIYKIQKELEEKRRS 660
>gi|2996629|gb|AAC08447.1| CBP [Homo sapiens]
          Length = 555

 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 46/106 (43%), Positives = 54/106 (50%), Gaps = 9/106 (8%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +QL LLLHAH+C RR+    E            C +  C  MK VL HMT C+ G  
Sbjct: 87  LIQQQLVLLLHAHKCQRREQANGEVRA---------CSLPHCRTMKNVLNHMTHCQAGKA 137

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTPAEP 109
           C   HCASSR I+SHWK C   +CPVC P+        Q T    P
Sbjct: 138 CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSP 183

 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 23/93 (24%), Positives = 46/93 (49%)

Query: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164
           T A P      + WH  V +  RS L+ K+ + I     P  L + +M+    Y++  E 
Sbjct: 313 TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG 372

Query: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
            ++++A   + YYH+  EK+ + Q+    ++++
Sbjct: 373 DMYESANSRDEYYHLLAEKIYKIQKELEEKRRS 405
>gi|4557557|ref|NP_001420.1| E1A binding protein p300; E1A-binding protein, 300kD [Homo sapiens]
 gi|3024341|sp|Q09472|P300_HUMAN E1A-associated protein p300
 gi|627657|pir||A54277 transcription adaptor protein p300 - human
 gi|495301|gb|AAA18639.1| p300 protein
          Length = 2414

 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 43/90 (47%), Positives = 52/90 (57%), Gaps = 9/90 (10%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +QL LLLHAH+C RR+    E  +         C +  C  MK VL HMT C+ G  
Sbjct: 337 LIQQQLVLLLHAHKCQRREQANGEVRQ---------CNLPHCRTMKNVLNHMTHCQSGKS 387

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPI 93
           C   HCASSR I+SHWK C   +CPVC P+
Sbjct: 388 CQVAHCASSRQIISHWKNCTRHDCPVCLPL 417

 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 23/93 (24%), Positives = 47/93 (50%)

Query: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164
           T A+P      + WH ++ +  R+ L+ K+ + I     P  L + +M+    Y+R  E 
Sbjct: 558 TAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG 617

Query: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
            ++++A     YYH+  EK+ + Q+    +++T
Sbjct: 618 DMYESANNRAEYYHLLAEKIYKIQKELEEKRRT 650
>gi|631119|pir||S39162 transcription coactivator CREB-binding protein - human
          Length = 2440

 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 46/106 (43%), Positives = 54/106 (50%), Gaps = 9/106 (8%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +QL LLLHAH+C RR+    E            C +  C  MK VL HMT C+ G  
Sbjct: 353 LIQQQLVLLLHAHKCQRREQANGEVRA---------CSLPHCRTMKNVLNHMTHCQAGKA 403

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTPAEP 109
           C   HCASSR I+SHWK C   +CPVC P+        Q T    P
Sbjct: 404 CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSP 449

 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 23/93 (24%), Positives = 46/93 (49%)

Query: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164
           T A P      + WH  V +  RS L+ K+ + I     P  L + +M+    Y++  E 
Sbjct: 579 TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG 638

Query: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
            ++++A   + YYH+  EK+ + Q+    ++++
Sbjct: 639 DMYESANSRDEYYHLLAEKIYKIQKELEEKRRS 671
>gi|4758056|ref|NP_004371.1| CREB binding protein [Homo sapiens]
 gi|3023440|sp|Q92793|CBP_HUMAN CREB-binding protein
 gi|2443859|gb|AAC51770.1| CREB-binding protein
          Length = 2442

 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 46/106 (43%), Positives = 54/106 (50%), Gaps = 9/106 (8%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +QL LLLHAH+C RR+    E            C +  C  MK VL HMT C+ G  
Sbjct: 353 LIQQQLVLLLHAHKCQRREQANGEVRA---------CSLPHCRTMKNVLNHMTHCQAGKA 403

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTPAEP 109
           C   HCASSR I+SHWK C   +CPVC P+        Q T    P
Sbjct: 404 CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSP 449

 Score = 48.9 bits (115), Expect = 7e-05
 Identities = 23/93 (24%), Positives = 46/93 (49%)

Query: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164
           T A P      + WH  V +  RS L+ K+ + I     P  L + +M+    Y++  E 
Sbjct: 579 TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG 638

Query: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
            ++++A   + YYH+  EK+ + Q+    ++++
Sbjct: 639 DMYESANSRDEYYHLLAEKIYKIQKELEEKRRS 671
>gi|4321116|gb|AAC51331.2| CREB-binding protein [Homo sapiens]
          Length = 2442

 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 46/106 (43%), Positives = 54/106 (50%), Gaps = 9/106 (8%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +QL LLLHAH+C RR+    E            C +  C  MK VL HMT C+ G  
Sbjct: 353 LIQQQLVLLLHAHKCQRREQANGEVRA---------CSLPHCRTMKNVLNHMTHCQAGKA 403

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTPAEP 109
           C   HCASSR I+SHWK C   +CPVC P+        Q T    P
Sbjct: 404 CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSP 449

 Score = 48.9 bits (115), Expect = 7e-05
 Identities = 23/93 (24%), Positives = 46/93 (49%)

Query: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164
           T A P      + WH  V +  RS L+ K+ + I     P  L + +M+    Y++  E 
Sbjct: 579 TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG 638

Query: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
            ++++A   + YYH+  EK+ + Q+    ++++
Sbjct: 639 DMYESANSRDEYYHLLAEKIYKIQKELEEKRRS 671
>gi|19547885|gb|AAL87531.1| CREB-binding protein [Mus musculus]
 gi|19547887|gb|AAL87532.1| CREB-binding protein [Mus musculus]
          Length = 2429

 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 46/106 (43%), Positives = 54/106 (50%), Gaps = 9/106 (8%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +QL LLLHAH+C RR+    E            C +  C  MK VL HMT C+ G  
Sbjct: 346 LIQQQLVLLLHAHKCQRREQANGEVRA---------CSLPHCRTMKNVLNHMTHCQAGKA 396

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTPAEP 109
           C   HCASSR I+SHWK C   +CPVC P+        Q T    P
Sbjct: 397 CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSP 442

 Score = 48.9 bits (115), Expect = 7e-05
 Identities = 23/93 (24%), Positives = 46/93 (49%)

Query: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164
           T A P      + WH  V +  RS L+ K+ + I     P  L + +M+    Y++  E 
Sbjct: 572 TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG 631

Query: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
            ++++A   + YYH+  EK+ + Q+    ++++
Sbjct: 632 DMYESANSRDEYYHLLAEKIYKIQKELEEKRRS 664
>gi|21307831|gb|AAL54859.1| CREB-binding protein [Aplysia californica]
          Length = 2245

 Score = 75.9 bits (185), Expect = 5e-13
 Identities = 42/87 (48%), Positives = 52/87 (59%), Gaps = 10/87 (11%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +QL LLLHAH+C RR+    E            CK+  C  MK VL HMT+C +G  
Sbjct: 285 LIQQQLVLLLHAHKCQRREQNNIEQE----------CKLPYCRTMKNVLNHMTTCNKGKS 334

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVC 90
           C   HCASSR I++HWK C  ++CPVC
Sbjct: 335 CEVAHCASSRQIITHWKNCLRQDCPVC 361

 Score = 44.7 bits (104), Expect = 0.001
 Identities = 20/72 (27%), Positives = 38/72 (52%)

Query: 118 WHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAELQIFDTAQKLEAYY 177
           WH +V +  R+ L+ K+ + I       TL +++M     Y+R  E  ++++A     YY
Sbjct: 505 WHAQVTQDLRNHLVHKLVQAIFPTPDQATLRDSRMKNLVAYARKVEGDMYESANNRGQYY 564

Query: 178 HMAREKVCRYQE 189
           H+  EK+ + Q+
Sbjct: 565 HLLAEKIYKIQK 576
>gi|737920|prf||1923401A protein CBP
          Length = 2441

 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 45/106 (42%), Positives = 53/106 (50%), Gaps = 9/106 (8%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +QL LLLHAH+C RR+    E            C +  C  MK VL HMT C+    
Sbjct: 352 LIQQQLVLLLHAHKCQRREQANGEVRA---------CSLPHCRTMKNVLNHMTHCQAPKA 402

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTPAEP 109
           C   HCASSR I+SHWK C   +CPVC P+        Q T    P
Sbjct: 403 CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSP 448

 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 24/93 (25%), Positives = 46/93 (49%)

Query: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164
           T A P      + WH  V +  RS L+ K+ + I     P  L + +M+    Y++  E 
Sbjct: 578 TAAPPSSTGVRKGWHERVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG 637

Query: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
            ++++A   + YYH+  EK+ + Q+    +++T
Sbjct: 638 DMYESANSRDEYYHLLAEKIYKIQKELEEKRRT 670
>gi|1345703|sp|P45481|CBP_MOUSE CREB-binding protein
 gi|481698|pir||S39161 CREB-binding protein - mouse
 gi|435855|gb|AAB28651.1| CREB-binding protein; CBP [Mus sp.]
          Length = 2441

 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 45/106 (42%), Positives = 53/106 (50%), Gaps = 9/106 (8%)

Query: 4   LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
           LI +QL LLLHAH+C RR+    E            C +  C  MK VL HMT C+    
Sbjct: 352 LIQQQLVLLLHAHKCQRREQANGEVRA---------CSLPHCRTMKNVLNHMTHCQAPKA 402

Query: 64  CNSVHCASSRTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTPAEP 109
           C   HCASSR I+SHWK C   +CPVC P+        Q T    P
Sbjct: 403 CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSP 448

 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 24/93 (25%), Positives = 46/93 (49%)

Query: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164
           T A P      + WH  V +  RS L+ K+ + I     P  L + +M+    Y++  E 
Sbjct: 578 TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG 637

Query: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
            ++++A   + YYH+  EK+ + Q+    +++T
Sbjct: 638 DMYESANSRDEYYHLLAEKIYKIQKELEEKRRT 670
>gi|20664269|pdb|1L3E|B Chain B, Nmr Structures Of The Hif-1alpha CtadP300 CH1 COMPLEX
 gi|33357860|pdb|1P4Q|B Chain B, Solution Structure Of The Cited2 Transactivation Domain
          In Complex With The P300 Ch1 Domain
          Length = 101

 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 43/90 (47%), Positives = 52/90 (57%), Gaps = 9/90 (10%)

Query: 4  LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
          LI +QL LLLHAH+C RR+    E  +         C +  C  MK VL HMT C+ G  
Sbjct: 15 LIQQQLVLLLHAHKCQRREQANGEVRQ---------CNLPHCRTMKNVLNHMTHCQSGKS 65

Query: 64 CNSVHCASSRTILSHWKKCFNEECPVCKPI 93
          C   HCASSR I+SHWK C   +CPVC P+
Sbjct: 66 CQVAHCASSRQIISHWKNCTRHDCPVCLPL 95
>gi|20664319|pdb|1L8C|A Chain A, Structural Basis For Hif-1alphaCBP RECOGNITION IN THE
          Cellular Hypoxic Response
          Length = 95

 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 43/90 (47%), Positives = 51/90 (56%), Gaps = 9/90 (10%)

Query: 4  LISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPK 63
          LI +QL LLLHAH+C RR+    E            C +  C  MK VL HMT C+ G  
Sbjct: 8  LIQQQLVLLLHAHKCQRREQANGEVRA---------CSLPHCRTMKNVLNHMTHCQAGKA 58

Query: 64 CNSVHCASSRTILSHWKKCFNEECPVCKPI 93
          C   HCASSR I+SHWK C   +CPVC P+
Sbjct: 59 CQVAHCASSRQIISHWKNCTRHDCPVCLPL 88
>gi|7511830|pir||T13828 CREB-binding protein homolog - fruit fly (Drosophila melanogaster)
 gi|1916930|gb|AAB53050.1| CREB-binding protein homolog [Drosophila melanogaster]
          Length = 3190

 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 39/88 (44%), Positives = 48/88 (54%), Gaps = 9/88 (10%)

Query: 5   ISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPKC 64
           I +QL LLLHAH+C RR+         N      +C +  C  MK VL HM +CK+   C
Sbjct: 515 IQQQLMLLLHAHKCNRRE---------NLNPNREVCNVNYCKAMKSVLAHMGTCKQSKDC 565

Query: 65  NSVHCASSRTILSHWKKCFNEECPVCKP 92
              HCASSR IL H+K C N  C +C P
Sbjct: 566 TMQHCASSRQILLHYKTCQNSGCVICYP 593

 Score = 42.0 bits (97), Expect = 0.007
 Identities = 18/77 (23%), Positives = 38/77 (49%)

Query: 113  EHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAELQIFDTAQK 172
            ++++ W   V    R+ L+ K+ + I     P T+ + +M     Y+   E  +++ A+ 
Sbjct: 938  DNEKDWRESVTADLRNHLVHKLVQAIFPTSDPTTMQDKRMHNLVSYAEKVEKDMYEMAKS 997

Query: 173  LEAYYHMAREKVCRYQE 189
               YYH+  EK+ + Q+
Sbjct: 998  RSEYYHLLAEKIYKIQK 1014
>gi|24640865|ref|NP_524642.2| nejire CG15319-PB [Drosophila melanogaster]
 gi|22833041|gb|AAF46516.2| CG15319-PB [Drosophila melanogaster]
          Length = 3276

 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 39/88 (44%), Positives = 48/88 (54%), Gaps = 9/88 (10%)

Query: 5   ISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPKC 64
           I +QL LLLHAH+C RR+         N      +C +  C  MK VL HM +CK+   C
Sbjct: 515 IQQQLMLLLHAHKCNRRE---------NLNPNREVCNVNYCKAMKSVLAHMGTCKQSKDC 565

Query: 65  NSVHCASSRTILSHWKKCFNEECPVCKP 92
              HCASSR IL H+K C N  C +C P
Sbjct: 566 TMQHCASSRQILLHYKTCQNSGCVICYP 593

 Score = 41.6 bits (96), Expect = 0.009
 Identities = 18/77 (23%), Positives = 38/77 (49%)

Query: 113  EHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAELQIFDTAQK 172
            ++++ W   V    R+ L+ K+ + I     P T+ + +M     Y+   E  +++ A+ 
Sbjct: 938  DNEKDWRESVTADLRNHLVHKLVQAIFPTSDPTTMQDKRMHNLVSYAEKVEKDMYEMAKS 997

Query: 173  LEAYYHMAREKVCRYQE 189
               YYH+  EK+ + Q+
Sbjct: 998  RSEYYHLLAEKIYKIQK 1014
>gi|27663074|ref|XP_235502.1| similar to E1A-associated protein p300 [Rattus norvegicus]
          Length = 2156

 Score = 65.5 bits (158), Expect = 7e-10
 Identities = 27/46 (58%), Positives = 31/46 (67%)

Query: 48 MKEVLKHMTSCKEGPKCNSVHCASSRTILSHWKKCFNEECPVCKPI 93
          MK VL HMT C+ G  C   HCASSR I+SHWK C   +CPVC P+
Sbjct: 1  MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPL 46

 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 23/93 (24%), Positives = 47/93 (50%)

Query: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164
           T A+P      + WH ++ +  R+ L+ K+ + I     P  L + +M+    Y+R  E 
Sbjct: 187 TAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG 246

Query: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
            ++++A     YYH+  EK+ + Q+    +++T
Sbjct: 247 DMYESANNRAEYYHLLAEKIYKIQKELEEKRRT 279
>gi|27666550|ref|XP_235770.1| similar to E1A-associated protein p300 [Rattus norvegicus]
          Length = 1605

 Score = 65.5 bits (158), Expect = 7e-10
 Identities = 27/46 (58%), Positives = 31/46 (67%)

Query: 48 MKEVLKHMTSCKEGPKCNSVHCASSRTILSHWKKCFNEECPVCKPI 93
          MK VL HMT C+ G  C   HCASSR I+SHWK C   +CPVC P+
Sbjct: 1  MKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPL 46

 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 23/93 (24%), Positives = 47/93 (50%)

Query: 105 TPAEPKKPEHDQIWHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAEL 164
           T A+P      + WH ++ +  R+ L+ K+ + I     P  L + +M+    Y+R  E 
Sbjct: 187 TAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG 246

Query: 165 QIFDTAQKLEAYYHMAREKVCRYQEGFPRRQKT 197
            ++++A     YYH+  EK+ + Q+    +++T
Sbjct: 247 DMYESANNRAEYYHLLAEKIYKIQKELEEKRRT 279
>gi|7487910|pir||T01055 hypothetical protein YUP8H12R.38 - Arabidopsis thaliana
 gi|3152587|gb|AAC17068.1| Similar to CREB-binding protein homolog gb|U88570 from D.
           melanogaster and contains similarity to
           callus-associated protein gb|U01961 from Nicotiana
           tabacum.  EST gb|W43427 comes from this gene.
           [Arabidopsis thaliana]
          Length = 1516

 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 21/59 (35%), Positives = 36/59 (61%), Gaps = 1/59 (1%)

Query: 35  APHAMCKIQDCVIMKEVLKHMTSCKEGPKCNSVHCASSRTILSHWKKCFNEECPVCKPI 93
           AP   C  ++CV ++++ KHM SC   P+C+   C  ++T+++H + C    CPVC P+
Sbjct: 532 APEGKCPDRNCVTVQKLWKHMDSCA-APQCSYPRCLPTKTLINHHRSCKEPNCPVCIPV 589
>gi|18412221|ref|NP_565197.1| p300/CBP acetyltransferase-related protein 2 [Arabidopsis thaliana]
 gi|12597461|gb|AAG60059.1| p300/CBP acetyltransferase-related protein 2 [Arabidopsis thaliana]
          Length = 1654

 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 21/59 (35%), Positives = 36/59 (61%), Gaps = 1/59 (1%)

Query: 35  APHAMCKIQDCVIMKEVLKHMTSCKEGPKCNSVHCASSRTILSHWKKCFNEECPVCKPI 93
           AP   C  ++CV ++++ KHM SC   P+C+   C  ++T+++H + C    CPVC P+
Sbjct: 646 APEGKCPDRNCVTVQKLWKHMDSCA-APQCSYPRCLPTKTLINHHRSCKEPNCPVCIPV 703
>gi|15230656|ref|NP_187904.1| CREB-binding protein -related [Arabidopsis thaliana]
 gi|15795129|dbj|BAB02507.1| CREB-binding protein-like [Arabidopsis thaliana]
          Length = 1670

 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 16/84 (19%)

Query: 7   RQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPKCNS 66
           R L  LLH  +C         AAE N       C+ + C   K +LKH+  CK  P C  
Sbjct: 620 RWLLFLLHVRKC--------NAAEDN-------CESKYCFTAKTLLKHINCCK-APACAY 663

Query: 67  VHCASSRTILSHWKKCFNEECPVC 90
            +C  +R ++ H+K C +E CPVC
Sbjct: 664 QYCHQTRQLIHHYKHCGDEACPVC 687
>gi|21105780|gb|AAM34788.1|AF512558_2 HAC5 [Arabidopsis thaliana]
          Length = 1012

 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 16/84 (19%)

Query: 7   RQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPKCNS 66
           R L  LLH  +C         AAE N       C+ + C   K +LKH+  CK  P C  
Sbjct: 92  RWLLFLLHVRKC--------NAAEDN-------CESKYCFTAKTLLKHINCCK-APACAY 135

Query: 67  VHCASSRTILSHWKKCFNEECPVC 90
            +C  +R ++ H+K C +E CPVC
Sbjct: 136 QYCHQTRQLIHHYKHCGDEACPVC 159
>gi|15219327|ref|NP_173115.1| expressed protein [Arabidopsis thaliana]
          Length = 1706

 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 1/58 (1%)

Query: 36  PHAMCKIQDCVIMKEVLKHMTSCKEGPKCNSVHCASSRTILSHWKKCFNEECPVCKPI 93
           P   C+ Q+CV ++++  HM +C + P+C    C  ++ ++ H+K C +  CPVC P+
Sbjct: 660 PGGRCQDQNCVTVQKLWSHMDNCAD-PQCLYPRCRHTKALIGHYKNCKDPRCPVCVPV 716
>gi|7489105|pir||T02019 callus-associated protein - common tobacco (fragment)
 gi|432982|gb|AAA03633.1| callus associated protein
          Length = 670

 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 16/87 (18%)

Query: 7   RQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEGPKCNS 66
           R L  L+HA  C                AP   C   +C+  +++L+HM  C +   C  
Sbjct: 478 RWLLFLIHARRC---------------SAPEGKCPENNCIHAQKLLRHMERCIKF-DCPY 521

Query: 67  VHCASSRTILSHWKKCFNEECPVCKPI 93
             C  ++ +++H K C NE CPVC P+
Sbjct: 522 PRCPETKVLINHHKHCKNENCPVCIPV 548
>gi|25518555|pir||E86302 hypothetical protein F17F16.8 [imported] - Arabidopsis thaliana
 gi|9954734|gb|AAG09087.1|AC026237_8 Unknown Protein [Arabidopsis thaliana]
          Length = 1498

 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 1/58 (1%)

Query: 36  PHAMCKIQDCVIMKEVLKHMTSCKEGPKCNSVHCASSRTILSHWKKCFNEECPVCKPI 93
           P   C+ Q+CV ++++  HM +C + P+C    C  ++ ++ H+K C +  CPVC P+
Sbjct: 452 PGGRCQDQNCVTVQKLWSHMDNCAD-PQCLYPRCRHTKALIGHYKNCKDPRCPVCVPV 508
>gi|4139873|pdb|1KDX|A Chain A, Kix Domain Of Mouse Cbp (Creb Binding Protein) In Complex
           With Phosphorylated Kinase Inducible Domain (Pkid) Of
           Rat Creb (Cyclic Amp Response Element Binding Protein),
           Nmr 17 Structures
          Length = 81

 Score = 45.4 bits (106), Expect = 6e-04
 Identities = 20/72 (27%), Positives = 38/72 (52%)

Query: 118 WHLEVPKTYRSELIEKIYKGIMSNVKPGTLSEAQMDTWKEYSRSAELQIFDTAQKLEAYY 177
           WH  V +  RS L+ K+ + I     P  L + +M+    Y++  E  ++++A   + YY
Sbjct: 6   WHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYY 65

Query: 178 HMAREKVCRYQE 189
           H+  EK+ + Q+
Sbjct: 66  HLLAEKIYKIQK 77
>gi|8778322|gb|AAF79331.1|AC002304_24 F14J16.27 [Arabidopsis thaliana]
          Length = 1550

 Score = 35.8 bits (81), Expect = 0.51
 Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 17/94 (18%)

Query: 2   NTLISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEG 61
           NT++ R +  + HA  C          A+K++      C  + C   ++++KH+  CK  
Sbjct: 421 NTVL-RWIPFMFHARHC---------KAKKDK------CASKFCFQARKIVKHIDCCKV- 463

Query: 62  PKCNSVHCASSRTILSHWKKCFNEECPVCKPIIE 95
           P C   +C  +R  L H+K+C +  C  C  + E
Sbjct: 464 PNCKYRYCLGTRMWLDHFKQCKSISCRTCVAVRE 497
>gi|21105784|gb|AAM34789.1|AF512560_1 HAC4 [Arabidopsis thaliana]
          Length = 751

 Score = 35.8 bits (81), Expect = 0.57
 Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 17/94 (18%)

Query: 2   NTLISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEG 61
           NT++ R +  + HA  C          A+K++      C  + C   ++++KH+  CK  
Sbjct: 412 NTVL-RWIPFMFHARHC---------KAKKDK------CASKFCFQARKIVKHIDCCKV- 454

Query: 62  PKCNSVHCASSRTILSHWKKCFNEECPVCKPIIE 95
           P C   +C  +R  L H+K+C +  C  C  + E
Sbjct: 455 PNCKYRYCLGTRMWLDHFKQCKSISCRTCVAVRE 488
>gi|6056385|gb|AAF02849.1|AC009894_20 Unknown protein [Arabidopsis thaliana]
          Length = 1209

 Score = 35.8 bits (81), Expect = 0.58
 Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 17/94 (18%)

Query: 2   NTLISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEG 61
           NT++ R +  + HA  C          A+K++      C  + C   ++++KH+  CK  
Sbjct: 421 NTVL-RWIPFMFHARHC---------KAKKDK------CASKFCFQARKIVKHIDCCKV- 463

Query: 62  PKCNSVHCASSRTILSHWKKCFNEECPVCKPIIE 95
           P C   +C  +R  L H+K+C +  C  C  + E
Sbjct: 464 PNCKYRYCLGTRMWLDHFKQCKSISCRTCVAVRE 497
>gi|18405622|ref|NP_564706.1| CREB-binding protein -related [Arabidopsis thaliana]
          Length = 1456

 Score = 35.4 bits (80), Expect = 0.68
 Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 17/94 (18%)

Query: 2   NTLISRQLGLLLHAHECVRRDIKIREAAEKNEPAPHAMCKIQDCVIMKEVLKHMTSCKEG 61
           NT++ R +  + HA  C          A+K++      C  + C   ++++KH+  CK  
Sbjct: 421 NTVL-RWIPFMFHARHC---------KAKKDK------CASKFCFQARKIVKHIDCCKV- 463

Query: 62  PKCNSVHCASSRTILSHWKKCFNEECPVCKPIIE 95
           P C   +C  +R  L H+K+C +  C  C  + E
Sbjct: 464 PNCKYRYCLGTRMWLDHFKQCKSISCRTCVAVRE 497
  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF
    Posted date:  Sep 14, 2003  6:30 PM
  Number of letters in database: 490,609,399
  Number of sequences in database:  1,523,846
  
Lambda     K      H
   0.317    0.131    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,224,303
Number of Sequences: 1523846
Number of extensions: 393140
Number of successful extensions: 1096
Number of sequences better than  1.0: 3
Number of HSP's better than  1.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1089
Number of HSP's gapped (non-prelim): 3
length of query: 226
length of database: 490,609,399
effective HSP length: 120
effective length of query: 106
effective length of database: 307,747,879
effective search space: 32621275174
effective search space used: 32621275174
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 79 (35.0 bits)