RID=1057255345-019884-22949, PCAP

RID=1057255345-019884-22949, PCAP_HUMAN BLASTP 2.2.6 [Apr-09-2003]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402.
RID: 1057255345-019884-22949
Query= PCAP_HUMAN (128 letters)
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 1,463,011 sequences; 469,658,079 total letters
If you have any problems or questions with the results of this search
please refer to the BLAST FAQs
Results of PSI-Blast iteration 1
Distribution of 15 Blast Hits on the Query Sequence


Legend:
 - means that the alignment score was below the threshold on the previous iteration 
 - means that the alignment was checked on the previous iteration 


Hit list size 
Sequences with E-value BETTER than threshold
                                                                     Score    E
Sequences producing significant alignments:                          (bits) Value


 gi|21748618|dbj|BAC03446.1|  FLJ00386 protein [Homo sapiens]           174   3e-43 

 gi|27734440|sp|Q96RN5|PCAP_HUMAN  Positive cofactor 2 glutamine/Q...   174   3e-43 

 gi|21312134|ref|NP_056973.2|  positive cofactor 2, glutamine/Q-ri...   173   4e-43 

 gi|14276857|gb|AAK58423.1|AF328769_1  PC2-glutamine-rich-associat...   173   4e-43 

 gi|20177999|sp|Q924H2|PCAP_MOUSE  Positive cofactor 2 glutamine/Q...   168   2e-41 

 gi|15809028|ref|NP_291087.1|  positive cofactor 2, glutamine/Q-ri...   166   4e-41 

 gi|28279616|gb|AAH45472.1|  Similar to PC2 (positive cofactor 2, ...   129   6e-30 

 gi|20891927|ref|XP_147188.1|  positive cofactor 2, multiprotein c...   124   2e-28 

 gi|28374176|gb|AAH46263.1|  Similar to PC2 (positive cofactor 2, ...   124   4e-28 

 gi|3037135|gb|AAC12944.1|  TPA inducible protein [Homo sapiens]        121   2e-27 

 gi|21956190|gb|AAM83255.1|AF378334_1  ARC105 [Xenopus laevis]          112   1e-24 

 gi|19920468|ref|NP_608528.1|  CG4184-PA [Drosophila melanogaster]...    71   4e-12 


Sequences with E-value WORSE than threshold


 gi|25148756|ref|NP_741152.1|  Putative nuclear protein, nematode ...    38   0.037 

 gi|7506661|pir||T16726  hypothetical protein R12B2.5 - Caenorhabd...    38   0.037 

 gi|25148761|ref|NP_741151.1|  Putative nuclear protein, nematode ...    38   0.037 


Alignments







>gi|21748618|dbj|BAC03446.1|   FLJ00386 protein [Homo sapiens]
          Length = 811

 Score =  174 bits (440), Expect = 3e-43
 Identities = 89/89 (100%), Positives = 89/89 (100%)

Query: 1   MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
           MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 24  MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 83

Query: 61  RLIIHFRDIHNKKSQASVSDPMNALQSLT 89
           RLIIHFRDIHNKKSQASVSDPMNALQSLT
Sbjct: 84  RLIIHFRDIHNKKSQASVSDPMNALQSLT 112



>gi|27734440|sp|Q96RN5|PCAP_HUMAN   Positive cofactor 2 glutamine/Q-rich-associated protein (PC2
          glutamine/Q-rich-associated protein) (TPA-inducible
          gene-1) (TIG-1) (Activator-recruited cofactor 105 kDa
          component) (ARC105) (CTG repeat protein 7a)
          Length = 788

 Score =  174 bits (440), Expect = 3e-43
 Identities = 89/89 (100%), Positives = 89/89 (100%)

Query: 1  MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
          MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 1  MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60

Query: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLT 89
          RLIIHFRDIHNKKSQASVSDPMNALQSLT
Sbjct: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLT 89



>gi|21312134|ref|NP_056973.2|   positive cofactor 2, glutamine/Q-rich-associated protein; TPA
          inducible protein; TPA inducible gene-1;
          PC2-glutamine-rich-associated protein; trinucleotide
          repeat containing 7 [Homo sapiens]
 gi|15559260|gb|AAH13985.1|AAH13985   PC2 (positive cofactor 2, multiprotein complex)
          glutamine/Q-rich-associated protein [Homo sapiens]
          Length = 748

 Score =  173 bits (439), Expect = 4e-43
 Identities = 89/89 (100%), Positives = 89/89 (100%)

Query: 1  MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
          MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 1  MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60

Query: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLT 89
          RLIIHFRDIHNKKSQASVSDPMNALQSLT
Sbjct: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLT 89



>gi|14276857|gb|AAK58423.1|AF328769_1   PC2-glutamine-rich-associated protein [Homo sapiens]
          Length = 746

 Score =  173 bits (439), Expect = 4e-43
 Identities = 89/89 (100%), Positives = 89/89 (100%)

Query: 1  MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
          MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 1  MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60

Query: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLT 89
          RLIIHFRDIHNKKSQASVSDPMNALQSLT
Sbjct: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLT 89



>gi|20177999|sp|Q924H2|PCAP_MOUSE   Positive cofactor 2 glutamine/Q-rich-associated protein (PC2
          glutamine/Q-rich-associated protein) (mPcqap)
          Length = 792

 Score =  168 bits (425), Expect = 2e-41
 Identities = 86/89 (96%), Positives = 86/89 (96%)

Query: 1  MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
          MDV GQETDWRS AFR KLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 1  MDVWGQETDWRSAAFRLKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60

Query: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLT 89
          RLIIHFRDIHNKKSQASVSDPMNALQSLT
Sbjct: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLT 89



>gi|15809028|ref|NP_291087.1|   positive cofactor 2, glutamine/Q-rich-associated protein [Mus
          musculus]
 gi|14276859|gb|AAK58424.1|AF328770_1   PC2-glutamine-rich-associated protein [Mus musculus]
          Length = 667

 Score =  166 bits (421), Expect = 4e-41
 Identities = 86/89 (96%), Positives = 86/89 (96%)

Query: 1  MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
          MDV GQETDWRS AFR KLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
Sbjct: 1  MDVWGQETDWRSAAFRLKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60

Query: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLT 89
          RLIIHFRDIHNKKSQASVSDPMNALQSLT
Sbjct: 61 RLIIHFRDIHNKKSQASVSDPMNALQSLT 89



>gi|28279616|gb|AAH45472.1|   Similar to PC2 (positive cofactor 2, multiprotein complex)
          glutamine/Q-rich-associated protein [Danio rerio]
          Length = 809

 Score =  129 bits (325), Expect = 6e-30
 Identities = 64/88 (72%), Positives = 76/88 (86%), Gaps = 2/88 (2%)

Query: 1  MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
          MDV G ++DWRS AFRQK+V+QIE+AMRKAG  H+KSS +MESHVF KAKTR+EYLS+VA
Sbjct: 1  MDVPGPDSDWRSPAFRQKVVAQIEEAMRKAGTGHTKSSTEMESHVFTKAKTREEYLSMVA 60

Query: 61 RLIIHFRDIHNKKSQASVSDPMNALQSL 88
          RLIIHFRDIH KK+Q    DP+NALQ+L
Sbjct: 61 RLIIHFRDIH-KKAQGG-PDPINALQNL 86



>gi|20891927|ref|XP_147188.1|   positive cofactor 2, multiprotein complex,
          glutamine/Q-rich-associated protein [Mus musculus]
          Length = 763

 Score =  124 bits (312), Expect = 2e-28
 Identities = 63/63 (100%), Positives = 63/63 (100%)

Query: 27 MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQ 86
          MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQ
Sbjct: 1  MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQ 60

Query: 87 SLT 89
          SLT
Sbjct: 61 SLT 63



>gi|28374176|gb|AAH46263.1|   Similar to PC2 (positive cofactor 2, multiprotein complex)
          glutamine/Q-rich-associated protein [Xenopus laevis]
          Length = 846

 Score =  124 bits (310), Expect = 4e-28
 Identities = 62/73 (84%), Positives = 70/73 (95%)

Query: 17 QKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQA 76
          QKLVSQI++AMRKAGVAH+KSSK+MESHVFLKAKTR+EYLSLVARLIIHFRDI NKK+Q 
Sbjct: 1  QKLVSQIDEAMRKAGVAHTKSSKEMESHVFLKAKTREEYLSLVARLIIHFRDIFNKKNQT 60

Query: 77 SVSDPMNALQSLT 89
          + SDPMNALQ+LT
Sbjct: 61 AASDPMNALQNLT 73



>gi|3037135|gb|AAC12944.1|   TPA inducible protein [Homo sapiens]
          Length = 579

 Score =  121 bits (304), Expect = 2e-27
 Identities = 63/63 (100%), Positives = 63/63 (100%)

Query: 27 MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQ 86
          MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQ
Sbjct: 1  MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQ 60

Query: 87 SLT 89
          SLT
Sbjct: 61 SLT 63



>gi|21956190|gb|AAM83255.1|AF378334_1   ARC105 [Xenopus laevis]
          Length = 754

 Score =  112 bits (280), Expect = 1e-24
 Identities = 56/63 (88%), Positives = 61/63 (96%)

Query: 27 MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQ 86
          MRKAGVAH+KSSKDMESHVFLKAKTR+EYLSLVARLIIHFRDI NKKSQA+ +DPMNALQ
Sbjct: 1  MRKAGVAHTKSSKDMESHVFLKAKTREEYLSLVARLIIHFRDILNKKSQAAATDPMNALQ 60

Query: 87 SLT 89
          +LT
Sbjct: 61 NLT 63



>gi|19920468|ref|NP_608528.1|   CG4184-PA [Drosophila melanogaster]
 gi|5052530|gb|AAD38595.1|AF145620_1   BcDNA.GH03922 [Drosophila melanogaster]
 gi|7296198|gb|AAF51490.1|   CG4184-PA [Drosophila melanogaster]
          Length = 749

 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 35/101 (34%), Positives = 56/101 (55%), Gaps = 21/101 (20%)

Query: 9   DWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRD 68
           DW+S  FRQ ++S+I D +       +K++  ME+H+F K++T+DEYL LVA+L +H++D
Sbjct: 4   DWQSQKFRQNVISKIHDLLPPNAQDQTKNAGVMENHIFRKSRTKDEYLGLVAKLFMHYKD 63

Query: 69  IHNKK---------------------SQASVSDPMNALQSL 88
           +  K                       Q  + DP+NALQ+L
Sbjct: 64  MSRKSQQQQQQQQQQGGPPPNAEMGGGQNMMQDPLNALQNL 104



>gi|25148756|ref|NP_741152.1|   Putative nuclear protein, nematode specific [Caenorhabditis
          elegans]
 gi|21363104|sp|Q21955|YNL5_CAEEL   Hypothetical protein R12B2.5 in chromosome III
 gi|17976542|gb|AAA50743.3|   Hypothetical protein R12B2.5a [Caenorhabditis elegans]
          Length = 780

 Score = 37.7 bits (86), Expect = 0.037
 Identities = 16/62 (25%), Positives = 34/62 (54%), Gaps = 5/62 (8%)

Query: 7  ETDWRSTAFRQKLVSQIEDAMRK-----AGVAHSKSSKDMESHVFLKAKTRDEYLSLVAR 61
          E DW S  FR+ ++ ++E  + +       +     ++ +E +VF K  ++DEY+  +A+
Sbjct: 3  EEDWPSPKFREHVIQRLEPELARNRQNAPNLPVPGDARQVEEYVFAKCMSKDEYMRTIAK 62

Query: 62 LI 63
          +I
Sbjct: 63 VI 64



>gi|7506661|pir||T16726   hypothetical protein R12B2.5 - Caenorhabditis elegans
          Length = 760

 Score = 37.7 bits (86), Expect = 0.037
 Identities = 16/62 (25%), Positives = 34/62 (54%), Gaps = 5/62 (8%)

Query: 7  ETDWRSTAFRQKLVSQIEDAMRK-----AGVAHSKSSKDMESHVFLKAKTRDEYLSLVAR 61
          E DW S  FR+ ++ ++E  + +       +     ++ +E +VF K  ++DEY+  +A+
Sbjct: 3  EEDWPSPKFREHVIQRLEPELARNRQNAPNLPVPGDARQVEEYVFAKCMSKDEYMRTIAK 62

Query: 62 LI 63
          +I
Sbjct: 63 VI 64



>gi|25148761|ref|NP_741151.1|   Putative nuclear protein, nematode specific [Caenorhabditis
          elegans]
 gi|21450526|gb|AAM54164.1|U00066_6   Hypothetical protein R12B2.5b [Caenorhabditis elegans]
          Length = 777

 Score = 37.7 bits (86), Expect = 0.037
 Identities = 16/62 (25%), Positives = 34/62 (54%), Gaps = 5/62 (8%)

Query: 7  ETDWRSTAFRQKLVSQIEDAMRK-----AGVAHSKSSKDMESHVFLKAKTRDEYLSLVAR 61
          E DW S  FR+ ++ ++E  + +       +     ++ +E +VF K  ++DEY+  +A+
Sbjct: 3  EEDWPSPKFREHVIQRLEPELARNRQNAPNLPVPGDARQVEEYVFAKCMSKDEYMRTIAK 62

Query: 62 LI 63
          +I
Sbjct: 63 VI 64






  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF
    Posted date:  Jul 1, 2003  3:46 AM
  Number of letters in database: 469,658,079
  Number of sequences in database:  1,463,011
  
Lambda     K      H
   0.315    0.124    0.333 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,292,720
Number of Sequences: 1463011
Number of extensions: 1759592
Number of successful extensions: 5252
Number of sequences better than  1.0: 15
Number of HSP's better than  1.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 5236
Number of HSP's gapped (non-prelim): 15
length of query: 128
length of database: 469,658,079
effective HSP length: 104
effective length of query: 24
effective length of database: 317,504,935
effective search space: 7620118440
effective search space used: 7620118440
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)