HumanPRENbase
Database of Prenylated Human
Proteins and their Orthologues

Protein CaaX Farnesylation, CaaX Geranylgeranylation and Rab Geranylgeranylation


CLUSTER parameter selection

REQUIRE one of the features for at least one member of listed clusters:
Status-LIKELY
EXCLUDE clusters with the following features for at least one member:
Status-KNOWN Status-NEW Status-OUT-OF-CONTEXT
Other features for cluster members are ALLOWED.
Minimum cluster-size: 1

SEQUENCE parameter selection

INCLUDE entries with the following features:
Viruses Mammalia Aves Amphibia Fishes Insecta Nematoda Fungi Plants Other-Eukaryota
EXCLUDE entries with the following features:
Synthetic-constructs
Ranked by evOluation of full cluster

Querycode: Hcs0200ce111ct11111111111111cm1se111st00202222222221r2 (save for easy recovery of the identical query parameters)
 Clusters  Selected Sequences
General Information Stats Stats Enzyme Taxonomic Kingdom Taxonomic Detail Eukaryota
Status Rank ClustID Name Pren Total PC EvO Number PC EvO FT GGT1 GGT2 Viruses Synthetic Eukaryota Mammalia Birds Amphibia Fishes Insecta Nematoda Fungi Plants Other
* 1 54695838
(2 isoinpas)
RAB5C, member RAS oncogene family 35 36 22.667 34.028 35
Explore
22.667 34.028 0 0 35 0 0 35 4 1 1 2 2 0 11 7 7
* 2 10880989
(no isoinpas)
RAB18 long isoform, member RAS oncogene family 22 22 15.750 22.000 22
Explore
15.750 22.000 8 4 22 0 0 22 3 1 2 2 4 2 1 4 3
* 3 7661922
(3 isoinpas)
RAB21, member RAS oncogene family 16 16 8.167 16.000 16
Explore
8.167 16.000 0 0 16 0 0 16 5 0 1 1 2 2 0 1 4
* 4 234746
(no isoinpas)
RAS-related protein MEL 15 15 4.667 15.000 15
Explore
4.667 15.000 2 2 15 0 0 15 2 0 0 0 0 0 5 6 2
* 5 19067861
(no isoinpas)
RAB3C, member RAS oncogene family 14 14 6.000 14.000 14
Explore
6.000 14.000 0 0 14 0 0 14 5 1 0 1 2 2 0 0 3
* 6 28422140
(3 isoinpas)
RAB4B, member RAS oncogene family 13 14 8.000 12.071 13
Explore
8.000 12.071 1 0 13 1 0 12 2 0 1 2 1 1 4 0 1
* 7 4506405
(2 isoinpas)
RALB - v-ral simian leukemia viral oncogene homolog B; v-ral simian leukemia viral oncogene homolog B 12 13 4.167 11.077 11
Explore
3.750 9.308 11 11 0 0 0 11 5 1 1 2 0 0 0 0 2
* 8 54311161
(2 isoinpas)
RAB33B, member RAS oncogene family 12 13 6.000 11.077 12
Explore
6.000 11.077 0 0 12 0 0 12 5 1 2 1 0 2 0 0 1
* 9 51036601
(2 isoinpas)
RAB6B, member RAS oncogene family 12 13 5.000 11.077 12
Explore
5.000 11.077 0 0 12 0 0 12 2 0 1 2 0 0 5 0 2
* 10 19923483
(2 isoinpas)
RAB14, member RAS oncogene family 11 11 4.167 11.000 11
Explore
4.167 11.000 0 0 11 0 0 11 2 0 0 2 3 2 0 0 2
* 11 7706567
(2 isoinpas)
guanine nucleotide binding protein G protein, gamma 13 12 14 5.000 10.286 12
Explore
5.000 10.286 12 12 0 0 0 12 4 1 2 2 3 0 0 0 0
* 12 25304086
(6 isoinpas)
RAB5B, member RAS oncogene family 11 13 4.167 9.308 11
Explore
4.167 9.308 0 0 11 0 0 11 4 1 1 0 0 0 4 0 1
* 13 54696894
(2 isoinpas)
RAB32, member RAS oncogene family 10 11 3.333 9.091 9
Explore
3.000 7.364 0 0 9 0 0 9 3 1 0 2 3 0 0 0 0
* 14 33150648
(3 isoinpas)
RAB24, member RAS oncogene family 9 9 3.000 9.000 9
Explore
3.000 9.000 0 0 9 0 0 9 4 1 1 3 0 0 0 0 0
* 15 10636479
(3 isoinpas)
RAB22A, member RAS oncogene family 9 9 3.000 9.000 8
Explore
2.667 7.111 0 0 8 0 0 8 4 1 1 2 0 0 0 0 0
* 16 32698769
(no isoinpas)
guanine nucleotide binding protein G protein, gamma 7 9 9 2.917 9.000 9
Explore
2.917 9.000 9 9 0 0 0 9 4 0 1 2 1 1 0 0 0
* 17 31616611
(2 isoinpas)
RAP2C, member RAS oncogene family 9 9 4.000 9.000 9
Explore
4.000 9.000 9 2 0 0 0 9 2 1 1 3 1 1 0 0 0
* 18 21361884
(2 isoinpas)
RAB2B, member RAS oncogene family 9 9 3.750 9.000 9
Explore
3.750 9.000 1 0 9 0 0 9 3 0 2 0 0 0 1 1 2
* 19 6841496
(3 isoinpas)
RAB23, member RAS oncogene family 12 16 6.000 9.000 12
Explore
6.000 9.000 10 6 11 0 0 12 4 1 1 1 3 0 0 0 2
* 20 14041910
(4 isoinpas)
RAB34, member RAS oncogene family 10 12 2.500 8.333 9
Explore
2.250 6.750 0 0 9 0 0 9 6 0 1 2 0 0 0 0 0
* 21 25188193
(2 isoinpas)
RAB39B, member RAS oncogene family 9 10 3.750 8.100 9
Explore
3.750 8.100 0 0 9 0 0 9 2 1 0 1 3 2 0 0 0
* 22 5729997
(no isoinpas)
RAB27B, member RAS oncogene family 9 10 3.000 8.100 9
Explore
3.000 8.100 0 0 9 0 0 9 5 0 2 1 0 1 0 0 0
* 23 7705963
(no isoinpas)
RAB9B, member RAS oncogene family 8 8 2.667 8.000 8
Explore
2.667 8.000 0 0 8 0 0 8 5 1 0 1 1 0 0 0 0
* 24 46195789
(2 isoinpas)
RAB40C/RAR3, member RAS oncogene family 8 8 2.667 8.000 8
Explore
2.667 8.000 8 0 8 0 0 8 2 0 1 1 4 0 0 0 0
* 25 8923401
(2 isoinpas)
RAB20, member RAS oncogene family 8 9 3.333 7.111 8
Explore
3.333 7.111 1 0 8 0 0 8 3 1 1 2 0 0 0 0 1
* 26 52789391
(2 isoinpas)
RAB43, member RAS oncogene family 8 9 2.667 7.111 8
Explore
2.667 7.111 0 0 8 0 0 8 2 1 0 0 3 2 0 0 0
* 27 21634443
(3 isoinpas)
RAB25, member RAS oncogene family 7 7 1.000 7.000 7
Explore
1.000 7.000 3 0 6 0 0 7 5 0 2 0 0 0 0 0 0
* 28 4759000
(no isoinpas)
RAB3D, member RAS oncogene family 7 7 1.750 7.000 6
Explore
1.500 5.143 0 0 6 0 0 6 4 0 1 0 0 0 0 0 1
* 29 16741621
(no isoinpas)
RAB37A, member RAS oncogene family 7 7 1.750 7.000 7
Explore
1.750 7.000 1 0 7 0 0 7 4 0 0 1 0 2 0 0 0
* 30 11641237
(no isoinpas)
RAB38, member RAS oncogene family 7 7 2.333 7.000 7
Explore
2.333 7.000 0 0 7 0 0 7 4 1 0 1 0 0 0 0 1
* 31 27486592
(5 isoinpas)
RAB40B/RAR2, member RAS oncogene family 7 7 2.333 7.000 7
Explore
2.333 7.000 7 0 7 0 0 7 4 1 1 1 0 0 0 0 0
* 32 54695950
(no isoinpas)
RAB7L1, member RAS oncogene family 7 7 1.750 7.000 6
Explore
1.500 5.143 0 0 6 0 0 6 4 0 1 0 0 0 0 0 1
* 33 54696976
(3 isoinpas)
M-Ras, muscle RAS oncogene homolog, R-Ras3 9 12 3.750 6.750 9
Explore
3.750 6.750 9 7 0 0 0 9 4 1 1 1 0 2 0 0 0
* 34 1457956
(2 isoinpas)
RAB30, member RAS oncogene family 10 15 4.500 6.667 10
Explore
4.500 6.667 0 0 10 0 0 10 2 1 2 2 1 2 0 0 0
* 35 33150588
(2 isoinpas)
RhoJ - Rho-related GTP-binding protein 6 6 2.000 6.000 6
Explore
2.000 6.000 6 3 0 0 0 6 3 1 1 1 0 0 0 0 0
* 36 38016957
(2 isoinpas)
RhoF - Rho-related GTP-binding protein 6 6 2.000 6.000 6
Explore
2.000 6.000 6 6 0 0 0 6 3 1 1 1 0 0 0 0 0
* 37 4758996
(2 isoinpas)
RAB33A, member of RAS oncogene family, S10 6 6 1.000 6.000 5
Explore
0.833 4.167 0 0 5 0 0 5 4 0 1 0 0 0 0 0 0
* 38 106187
(2 isoinpas)
RAB3B, member RAS oncogene family 6 7 0.667 5.143 6
Explore
0.667 5.143 0 0 6 0 0 6 5 0 0 0 0 0 0 0 1
* 39 40255119
(no isoinpas)
RAB45, RAS and EF hand domain containing 6 7 1.500 5.143 6
Explore
1.500 5.143 0 0 6 0 0 6 3 0 0 1 0 2 0 0 0
* 40 27734452
(no isoinpas)
RAB15, member RAS oncogene family 6 7 0.833 5.143 6
Explore
0.833 5.143 0 0 6 0 0 6 4 0 0 2 0 0 0 0 0
* 41 4757770
(no isoinpas)
RhoH - Rho-related GTP-binding protein 6 7 1.500 5.143 6
Explore
1.500 5.143 6 0 0 0 0 6 4 1 0 1 0 0 0 0 0
* 42 39930371
(2 isoinpas)
RAB39A, member RAS oncogene family 5 5 1.250 5.000 5
Explore
1.250 5.000 0 0 5 0 0 5 3 1 0 0 0 0 0 0 1
* 43 12052816
(3 isoinpas)
RAB17, member RAS oncogene family 5 5 1.250 5.000 5
Explore
1.250 5.000 0 0 5 0 0 5 3 1 0 1 0 0 0 0 0
* 44 1705960
(4 isoinpas)
Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit 6 8 1.667 4.500 6
Explore
1.667 4.500 6 3 0 0 0 6 3 1 1 1 0 0 0 0 0
* 45 36036
(3 isoinpas)
RhoG - Rho-related GTP-binding protein 6 8 2.000 4.500 6
Explore
2.000 4.500 6 6 0 0 0 6 2 1 1 2 0 0 0 0 0
* 46 54695756
(no isoinpas)
RAC3 - RAS-related C3 botulinum toxin substrate 3 5 6 1.333 4.167 5
Explore
1.333 4.167 5 5 0 0 0 5 2 1 0 1 0 0 0 0 1
* 47 37545057
(no isoinpas)
RAB12, member RAS oncogene family 5 6 0.250 4.167 5
Explore
0.250 4.167 0 0 5 0 0 5 5 0 0 0 0 0 0 0 0
* 48 50949371
(7 isoinpas)
hypothetical coiled-coil protein 5 6 0.667 4.167 5
Explore
0.667 4.167 5 0 0 0 0 5 4 0 0 1 0 0 0 0 0
* 49 15277321
(no isoinpas)
RAS-like, family 10, member B 5 6 1.250 4.167 5
Explore
1.250 4.167 5 5 0 0 0 5 3 0 1 1 0 0 0 0 0
* 50 33589861
(3 isoinpas)
RAB31, member RAS oncogene family 5 6 0.833 4.167 4
Explore
0.667 2.667 0 0 4 0 0 4 3 0 0 1 0 0 0 0 0
* 51 23503303
(no isoinpas)
conserved serine-threonine kinase 7 12 1.750 4.083 7
Explore
1.750 4.083 7 7 0 0 0 7 4 0 0 0 2 1 0 0 0
* 52 5454030
(no isoinpas)
RRP22, RAS-related on chromosome 22 4 4 0.333 4.000 4
Explore
0.333 4.000 4 4 0 0 0 4 4 0 0 0 0 0 0 0 0
* 53 21758015
(6 isoinpas)
DnaJA4 - DnaJ/Hsp40 homolog, subfamily A, member 4 10 25 5.000 4.000 10
Explore
5.000 4.000 10 0 0 1 0 9 5 1 0 0 1 1 0 0 1
* 54 38327539
(2 isoinpas)
72kDa inositol polyphosphate-5-phosphatase E 5 7 1.250 3.571 5
Explore
1.250 3.571 5 0 0 0 0 5 2 1 0 0 2 0 0 0 0
* 55 54695658
(no isoinpas)
RhoN - Rho-related GTP-binding protein 4 5 0.667 3.200 4
Explore
0.667 3.200 4 4 0 0 0 4 3 0 0 1 0 0 0 0 0
* 56 51466533
(3 isoinpas)
RAB19, member RAS oncogene family 4 5 0.667 3.200 4
Explore
0.667 3.200 0 0 4 0 0 4 3 1 0 0 0 0 0 0 0
* 57 28376635
(no isoinpas)
RAB37B, member RAS oncogene family 4 5 0.667 3.200 4
Explore
0.667 3.200 0 0 4 0 0 4 2 0 0 0 2 0 0 0 0
* 58 46361978
(4 isoinpas)
RAB26, member RAS oncogene family 4 5 0.667 3.200 4
Explore
0.667 3.200 0 0 4 0 0 4 3 1 0 0 0 0 0 0 0
* 59 33348830
(3 isoinpas)
RAB36, member RAS oncogene family 4 5 0.667 3.200 4
Explore
0.667 3.200 0 0 4 0 0 4 3 1 0 0 0 0 0 0 0
* 60 5454028
(no isoinpas)
R-Ras, related RAS viral r-ras oncogene homolog 4 5 0.333 3.200 4
Explore
0.333 3.200 4 4 0 0 0 4 4 0 0 0 0 0 0 0 0
* 61 4758690
(3 isoinpas)
leucine rich repeat in FLII interacting protein 1 4 5 0.333 3.200 4
Explore
0.333 3.200 4 0 0 0 0 4 4 0 0 0 0 0 0 0 0
* 62 51474992
(no isoinpas)
low complexity rich protein 3 3 0.250 3.000 3
Explore
0.250 3.000 3 3 0 0 0 3 3 0 0 0 0 0 0 0 0
* 63 31559833
(no isoinpas)
E-Ras, small GTPase 3 3 0.250 3.000 3
Explore
0.250 3.000 3 0 0 0 0 3 3 0 0 0 0 0 0 0 0
* 64 15147246
(no isoinpas)
G protein, gamma 8 3 3 0.500 3.000 3
Explore
0.500 3.000 3 3 0 0 0 3 2 0 0 1 0 0 0 0 0
* 65 7710129
(3 isoinpas)
LIM domain only 6 4 6 0.250 2.667 4
Explore
0.250 2.667 4 0 0 0 0 4 4 0 0 0 0 0 0 0 0
* 66 38490537
(2 isoinpas)
RAB7B, member RAS oncogene family 3 4 0.500 2.250 3
Explore
0.500 2.250 0 0 3 0 0 3 2 0 1 0 0 0 0 0 0
* 67 21361653
(2 isoinpas)
hypothetical coiled-coil protein FLJ20364 4 8 0.667 2.000 4
Explore
0.667 2.000 4 0 0 0 0 4 3 1 0 0 0 0 0 0 0
* 68 55661671
(no isoinpas)
RAB18 short isoform, member RAS oncogene family 2 3 0.167 1.333 2
Explore
0.167 1.333 2 2 1 0 0 2 2 0 0 0 0 0 0 0 0
* 69 37546274
(no isoinpas)
similar to RAB6A, member RAS oncogene family 1 1 0.083 1.000 1
Explore
0.083 1.000 0 0 1 0 0 1 1 0 0 0 0 0 0 0 0
* 70 27501389
(no isoinpas)
similar to RAC1 RAS-related C3 botulinum toxin substrate 1 1 1 0.083 1.000 1
Explore
0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
* 71 12060820
(no isoinpas)
serologically defined breast cancer antigen NY-BR-15, coiled coil 1 1 0.083 1.000 1
Explore
0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
* 72 55859596
(4 isoinpas)
PALM2, paralemmin 2, A kinase anchor protein 2 2 5 0.167 0.800 2
Explore
0.167 0.800 2 2 0 0 0 2 2 0 0 0 0 0 0 0 0
* 73 32171177
(no isoinpas)
OEBT over-expressed breast tumor LIM protein 1 4 0.083 0.250 1
Explore
0.083 0.250 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0

Your query selected 536 sequences in 73 clusters.