HumanPRENbase
Database of Prenylated Human
Proteins and their Orthologues

Protein CaaX Farnesylation, CaaX Geranylgeranylation and Rab Geranylgeranylation


CLUSTER parameter selection

REQUIRE one of the features for at least one member of listed clusters:
Status-NEW
EXCLUDE clusters with the following features for at least one member:
Status-KNOWN Status-LIKELY Status-OUT-OF-CONTEXT
Other features for cluster members are ALLOWED.
Minimum cluster-size: 1

SEQUENCE parameter selection

INCLUDE entries with the following features:
Viruses Mammalia Aves Amphibia Fishes Insecta Nematoda Fungi Plants Other-Eukaryota
EXCLUDE entries with the following features:
Synthetic-constructs
Ranked by evOluation of full cluster

Querycode: Hcs0020ce111ct11111111111111cm1se111st00202222222221r2 (save for easy recovery of the identical query parameters)
 Clusters  Selected Sequences
General Information Stats Stats Enzyme Taxonomic Kingdom Taxonomic Detail Eukaryota
Status Rank ClustID Name Pren Total PC EvO Number PC EvO FT GGT1 GGT2 Viruses Synthetic Eukaryota Mammalia Birds Amphibia Fishes Insecta Nematoda Fungi Plants Other
? 1 6330169
(no isoinpas)
DUF544, KIAA1164 protein 17 20 7.083 14.450 17
Explore
7.083 14.450 17 13 0 0 0 17 3 1 0 0 0 1 11 0 1
? 2 55777304
(3 isoinpas)
Ubiquitin-like 3 12 14 8.000 10.286 12
Explore
8.000 10.286 12 10 0 0 0 12 3 1 1 1 2 2 1 1 0
? 3 7243161
(3 isoinpas)
DUF544 10 11 4.167 9.091 10
Explore
4.167 9.091 10 9 0 0 0 10 5 0 1 0 0 1 1 2 0
? 4 42822891
(no isoinpas)
Selenoprotein W-related 9 9 3.000 9.000 9
Explore
3.000 9.000 9 8 0 0 0 9 3 1 0 2 3 0 0 0 0
? 5 21956647
(4 isoinpas)
ubiquitin specific protease 32 9 11 2.667 7.364 9
Explore
2.667 7.364 9 1 0 0 0 9 4 1 0 1 3 0 0 0 0
? 6 12314158
(3 isoinpas)
DUF1339, possibly integral membrane protein 11 21 4.583 5.762 11
Explore
4.583 5.762 11 2 0 0 0 11 4 1 0 1 3 2 0 0 0
? 7 3417289
(3 isoinpas)
C16orf45 homolog 6 7 1.500 5.143 6
Explore
1.500 5.143 6 6 0 0 0 6 4 1 0 1 0 0 0 0 0
? 8 40788968
(3 isoinpas)
KIAA0878 protein 5 5 0.833 5.000 5
Explore
0.833 5.000 5 5 0 0 0 5 4 1 0 0 0 0 0 0 0
? 9 6164721
(7 isoinpas)
F-box protein Fbl2 12 31 5.000 4.645 12
Explore
5.000 4.645 12 12 0 0 0 12 5 1 0 2 0 1 3 0 0
? 10 45501001
(4 isoinpas)
EHBP1 - EH domain binding protein 1 7 11 1.167 4.455 7
Explore
1.167 4.455 7 0 0 0 0 7 4 0 0 0 3 0 0 0 0
? 11 17402931
(2 isoinpas)
sperm associated antigen 11 isoform C precursor, secreted, similarity to beta-defensins = cysteine used as disulfide bridge? 4 4 0.333 4.000 4
Explore
0.333 4.000 4 0 0 0 0 4 4 0 0 0 0 0 0 0 0
? 12 50960731
(2 isoinpas)
DEAQ box polypeptide 1 RNA-dependent ATPase 4 4 0.333 4.000 4
Explore
0.333 4.000 4 0 0 0 0 4 4 0 0 0 0 0 0 0 0
? 13 50949308
(3 isoinpas)
hypothetical protein DPCD 6 11 1.500 3.273 6
Explore
1.500 3.273 6 0 0 0 0 6 4 1 0 1 0 0 0 0 0
? 14 34098968
(3 isoinpas)
lysozyme-like 2 6 11 0.833 3.273 5
Explore
0.833 2.273 4 1 0 0 0 5 4 0 0 0 1 0 0 0 0
? 15 41018470
(3 isoinpas)
WD and tetratricopeptide repeats protein 1 7 15 3.000 3.267 7
Explore
3.000 3.267 7 0 0 0 0 7 2 1 0 1 0 1 1 1 0
? 16 13775218
(no isoinpas)
cysteine-motif similar to RING finger 4 5 0.667 3.200 4
Explore
0.667 3.200 4 4 0 0 0 4 3 1 0 0 0 0 0 0 0
? 17 458692
(3 isoinpas)
WD repeat domain 42A 7 16 2.000 3.062 7
Explore
2.000 3.062 7 1 0 0 0 7 4 0 1 0 0 0 1 1 0
? 18 22062496
(3 isoinpas)
tangerin, calponin homology domain 3 3 0.250 3.000 3
Explore
0.250 3.000 3 0 0 0 0 3 3 0 0 0 0 0 0 0 0
? 19 34783118
(5 isoinpas)
DEAD/H Asp-Glu-Ala-Asp/His box polypeptide 32 4 6 0.667 2.667 4
Explore
0.667 2.667 4 0 0 0 0 4 3 0 1 0 0 0 0 0 0
? 20 13124858
(2 isoinpas)
stoned B-like factor SBLF, stonin 1 4 7 0.333 2.286 4
Explore
0.333 2.286 4 0 0 0 0 4 4 0 0 0 0 0 0 0 0
? 21 51458801
(no isoinpas)
TPR containing protein 3 4 0.250 2.250 3
Explore
0.250 2.250 3 1 0 0 0 3 3 0 0 0 0 0 0 0 0
? 22 55664133
(4 isoinpas)
novel protein 3 4 0.250 2.250 3
Explore
0.250 2.250 3 3 0 0 0 3 3 0 0 0 0 0 0 0 0
? 23 51468012
(2 isoinpas)
PREDICTED: hypothetical protein XP_498436 2 2 0.167 2.000 2
Explore
0.167 2.000 2 2 0 0 0 2 2 0 0 0 0 0 0 0 0
? 24 51471395
(no isoinpas)
C-terminal variation of peptidyl-prolyl cis-trans isomerase A 2 2 0.167 2.000 2
Explore
0.167 2.000 2 2 0 0 0 2 2 0 0 0 0 0 0 0 0
? 25 30353973
(no isoinpas)
Similar to N-terminus of solute carrier family 34 sodium phosphate, member 3 2 2 0.167 2.000 2
Explore
0.167 2.000 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
? 26 51477353
(no isoinpas)
WD40 repeats, similar to H326, WDR42A 2 2 0.167 2.000 2
Explore
0.167 2.000 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
? 27 47117499
(3 isoinpas)
Zinc finger CCCH type antiviral protein 1, Zinc finger CCCH type domain containing protein 2 3 5 0.167 1.800 3
Explore
0.167 1.800 3 0 0 0 0 3 3 0 0 0 0 0 0 0 0
? 28 34535072
(4 isoinpas)
Arrestin N- and C-terminal domains 5 14 1.000 1.786 5
Explore
1.000 1.786 5 0 0 0 0 5 2 0 2 1 0 0 0 0 0
? 29 4503113
(2 isoinpas)
cystatin M precursor 4 10 0.333 1.600 4
Explore
0.333 1.600 4 0 0 0 0 4 4 0 0 0 0 0 0 0 0
? 30 22658314
(2 isoinpas)
FAM83F, phospholipase D domain hit 3 6 0.250 1.500 3
Explore
0.250 1.500 3 0 0 0 0 3 3 0 0 0 0 0 0 0 0
? 31 27734755
(no isoinpas)
F-box and leucine-rich repeat protein 20 6 26 2.083 1.385 6
Explore
2.083 1.385 6 6 0 0 0 6 2 0 1 1 1 1 0 0 0
? 32 20562230
(no isoinpas)
PREDICTED: similar to caspase 14-like protein 2 3 0.167 1.333 2
Explore
0.167 1.333 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
? 33 37182964
(3 isoinpas)
ECEL1 - metallopeptidase 5 20 1.250 1.250 5
Explore
1.250 1.250 5 0 0 0 0 5 3 0 1 1 0 0 0 0 0
? 34 20270357
(no isoinpas)
similar to Arsenite inducible RNA associated protein 4 13 0.667 1.231 4
Explore
0.667 1.231 4 0 0 0 0 4 3 0 0 1 0 0 0 0 0
? 35 7705708
(2 isoinpas)
fls485, weak similarity to DnaJ chaperone 3 8 0.500 1.125 3
Explore
0.500 1.125 2 1 0 0 0 3 2 0 1 0 0 0 0 0 0
? 36 47077088
(no isoinpas)
unnamed protein 1 1 0.083 1.000 1
Explore
0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 37 21754420
(no isoinpas)
similar to At2g27390 1 1 0.083 1.000 1
Explore
0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 38 51492807
(2 isoinpas)
PREDICTED: hypothetical protein XP_380155 1 1 0.083 1.000 1
Explore
0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 39 51471094
(no isoinpas)
low complexity, proline-rich, PREDICTED: hypothetical protein XP_378365 1 1 0.083 1.000 1
Explore
0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 40 42660066
(no isoinpas)
PREDICTED: hypothetical protein XP_378394 1 1 0.083 1.000 1
Explore
0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 41 11360231
(no isoinpas)
hypothetical protein DKFZp761E13121.1 fragment 1 1 0.000 1.000 1
Explore
0.000 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 42 34531647
(no isoinpas)
unnamed protein 1 1 0.083 1.000 1
Explore
0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 43 34533082
(no isoinpas)
unnamed protein, similar to BT2029 from Bacteroides thetaiotaomicron 1 1 0.083 1.000 1
Explore
0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 44 28193148
(no isoinpas)
C14orf167 1 1 0.083 1.000 1
Explore
0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 45 51467487
(no isoinpas)
F-box protein 10 3 9 0.500 1.000 3
Explore
0.500 1.000 3 3 0 0 0 3 2 0 0 1 0 0 0 0 0
? 46 27479553
(no isoinpas)
PREDICTED: hypothetical protein XP_211089 1 1 0.083 1.000 1
Explore
0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 47 7690063
(no isoinpas)
aniridia protein, PAX6 fragment truncated through premature translational termination mutations 1 1 0.083 1.000 1
Explore
0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 48 37182490
(no isoinpas)
C-terminal variant of transmembrane Crumbs protein homolog 3 precursor 2 4 0.167 1.000 2
Explore
0.167 1.000 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
? 49 37182292
(no isoinpas)
WLPL514 1 1 0.083 1.000 1
Explore
0.083 1.000 1 1 0 0 0 1 1 0 0 0 0 0 0 0 0
? 50 3540176
(no isoinpas)
F23269_1, partial CDS 1 1 0.083 1.000 1
Explore
0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 51 41151611
(no isoinpas)
WD40 repeats, WDR42B 1 1 0.083 1.000 1
Explore
0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 52 51477210
(no isoinpas)
brain expressed X-linked-like 1 1 1 0.083 1.000 1
Explore
0.083 1.000 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 53 5174461
(2 isoinpas)
G protein-coupled receptor 109B, seven transmembrane helix 2 5 0.167 0.800 2
Explore
0.167 0.800 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
? 54 40674056
(2 isoinpas)
N-terminus contains part of Formin homology domain 2, C14orf173 protein 2 5 0.167 0.800 2
Explore
0.167 0.800 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
? 55 27262649
(2 isoinpas)
ataxin 2 related protein isoform C 3 14 0.250 0.643 3
Explore
0.250 0.643 3 0 0 0 0 3 3 0 0 0 0 0 0 0 0
? 56 4557335
(no isoinpas)
aspartoacylase 3 14 0.250 0.643 3
Explore
0.250 0.643 3 0 0 0 0 3 3 0 0 0 0 0 0 0 0
? 57 51475774
(2 isoinpas)
von Willebrand factor type A + BPTI/Kunitz family serine protease inhibitor domains 2 7 0.167 0.571 2
Explore
0.167 0.571 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
? 58 4505235
(2 isoinpas)
mannose-6-phosphate isomerase 7 86 1.750 0.570 7
Explore
1.750 0.570 7 7 0 0 0 7 5 1 0 1 0 0 0 0 0
? 59 51467591
(no isoinpas)
PREDICTED: hypothetical protein XP_499158 1 2 0.083 0.500 1
Explore
0.083 0.500 1 1 0 0 0 1 1 0 0 0 0 0 0 0 0
? 60 34530046
(no isoinpas)
unnamed protein, shares 24 N-terminal residues with Asialoglycoprotein receptor 1 1 2 0.083 0.500 1
Explore
0.083 0.500 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 61 51470845
(no isoinpas)
PREDICTED: hypothetical protein XP_498512 1 2 0.083 0.500 1
Explore
0.083 0.500 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 62 27451495
(no isoinpas)
tripartite motif protein 48, TRIM48; contains a RING, a B-box type 2, and a SPRY domain 1 2 0.083 0.500 1
Explore
0.083 0.500 0 1 0 0 0 1 1 0 0 0 0 0 0 0 0
? 63 51466681
(no isoinpas)
similar to N-terminus of putative eukaryotic translation initiation factor 3 subunit (eIF-3 1 2 0.083 0.500 1
Explore
0.083 0.500 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 64 8051621
(2 isoinpas)
2',5'-oligoadenylate synthetase 1 isoform E18 2 10 0.167 0.400 2
Explore
0.167 0.400 2 2 0 0 0 2 2 0 0 0 0 0 0 0 0
? 65 45708550
(no isoinpas)
DUF872 1 3 0.083 0.333 1
Explore
0.083 0.333 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 66 51476980
(no isoinpas)
N-terminal fragment of Piwi-like 4, PAZ domain, RNAI pathway 1 3 0.083 0.333 1
Explore
0.083 0.333 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 67 51466249
(no isoinpas)
similar to vomeronasal putative G-protein coupled receptor 1 3 0.083 0.333 1
Explore
0.083 0.333 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 68 21750201
(no isoinpas)
similar to C-terminus of Cat eye syndrome critical region protein 2 involved in cytoskeletal organisation 1 4 0.083 0.250 1
Explore
0.083 0.250 1 1 0 0 0 1 1 0 0 0 0 0 0 0 0
? 69 51464670
(no isoinpas)
similar to hypothetical protein L1H 3 region 1 4 0.083 0.250 1
Explore
0.083 0.250 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 70 24497591
(no isoinpas)
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit isoform 2 1 5 0.083 0.200 1
Explore
0.083 0.200 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 71 51476045
(no isoinpas)
weak similarity to carbonic anhydrase 1 5 0.083 0.200 1
Explore
0.083 0.200 1 1 0 0 0 1 1 0 0 0 0 0 0 0 0
? 72 55665766
(2 isoinpas)
heparanase 2, glycosyl hydrolase family 79 N-terminal domain 1 5 0.083 0.200 1
Explore
0.083 0.200 1 1 0 0 0 1 1 0 0 0 0 0 0 0 0
? 73 18676548
(no isoinpas)
FLJ00171 protein, contains N-terminal half of UhpC, Sugar phosphate permease domain 2 23 0.167 0.174 2
Explore
0.167 0.174 2 0 0 0 0 2 2 0 0 0 0 0 0 0 0
? 74 16307060
(no isoinpas)
Clathrin adaptor complex small chain, AP1S3 protein 1 6 0.083 0.167 1
Explore
0.083 0.167 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 75 37678114
(no isoinpas)
voltage-gated calcium channel beta 1 subunit splice variant CavB1d, contains SH3 domain 1 6 0.083 0.167 1
Explore
0.083 0.167 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 76 39918780
(no isoinpas)
synaptotagmin 14 splice variant 1 1 7 0.083 0.143 1
Explore
0.083 0.143 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 77 31874655
(no isoinpas)
fragment of IL2-inducible T-cell kinase 1 7 0.083 0.143 1
Explore
0.083 0.143 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 78 7385003
(no isoinpas)
integrin alpha 10 subunit 1 7 0.083 0.143 1
Explore
0.083 0.143 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 79 40353014
(no isoinpas)
Chondroitin N-acetylgalactosaminyltransferase 1 7 0.083 0.143 1
Explore
0.083 0.143 1 1 0 0 0 1 1 0 0 0 0 0 0 0 0
? 80 15559717
(no isoinpas)
Adaptin 1 9 0.083 0.111 1
Explore
0.083 0.111 1 1 0 0 0 1 1 0 0 0 0 0 0 0 0
? 81 33150550
(no isoinpas)
possible Armadillo-repeat 1 10 0.083 0.100 1
Explore
0.083 0.100 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 82 20336253
(no isoinpas)
palmitoyl-protein thioesterase 2 isoform c precursor 1 11 0.083 0.091 1
Explore
0.083 0.091 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 83 28279804
(no isoinpas)
Non-catalytic N-terminus of Alpha-2,8-sialyltransferase 8A 1 13 0.083 0.077 1
Explore
0.083 0.077 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 84 11360251
(no isoinpas)
hypothetical DKFZp761K2213.1 fragment - FHA, DIL, PDZ domain 1 15 0.083 0.067 1
Explore
0.083 0.067 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 85 28178838
(2 isoinpas)
isocitrate dehydrogenase 3 NAD+ gamma isoform b precursor 1 18 0.083 0.056 1
Explore
0.083 0.056 1 1 0 0 0 1 1 0 0 0 0 0 0 0 0
? 86 23065557
(no isoinpas)
glutathione S-transferase M4 isoform 2 1 18 0.083 0.056 1
Explore
0.083 0.056 1 1 0 0 0 1 1 0 0 0 0 0 0 0 0
? 87 46361987
(no isoinpas)
hydroxyacylglutathione hydrolase-like isoform 1 1 21 0.083 0.048 1
Explore
0.083 0.048 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 88 8922413
(no isoinpas)
hypothetical protein FLJ10415 1 26 0.083 0.038 1
Explore
0.083 0.038 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 89 15929807
(no isoinpas)
FLJ20125 protein, contains N-terminal half of Integrase core domain 1 27 0.083 0.037 1
Explore
0.083 0.037 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 90 1374863
(2 isoinpas)
CoxII/D-loop DNA fusion protein 1 70 0.000 0.014 1
Explore
0.000 0.014 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0
? 91 31871818
(no isoinpas)
interleukin-1 receptor associated kinase 4 mutant form 1 1 84 0.083 0.012 1
Explore
0.083 0.012 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0

Your query selected 269 sequences in 91 clusters.