Interesting domains

Only chordata within top2:

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam05902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 1 0 2 2 0 7 10 4_1_CTD

pfam00001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177 131 210 103 133 142 934 1684 7tm_1

pfam01661 3 0 0 2 0 2 2 3 0 3 4 2 0 0 2 1 0 0 1 1 2 3 1 25 15 12 A1pp

smart00506 3 0 0 2 0 3 2 2 1 3 4 2 0 0 3 1 2 2 1 1 2 5 6 31 15 14 A1pp

smart00608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 5 6 5 3 36 48 ACR

smart00552 2 0 0 0 0 1 1 2 1 0 1 2 0 1 1 1 1 1 5 1 4 3 4 4 13 11 ADEAMc

pfam05110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 2 2 2 23 32 AF-4

smart00248 79 0 0 8 12 15 23 44 20 44 75 76 1 9 76 22 7 14 126 90 295 151 190 146 637 521 ANK

smart00335 5 0 0 0 0 0 0 0 0 0 27 16 0 0 8 5 0 0 18 10 18 36 22 15 92 84 ANX

smart00177 91 1 1 17 10 22 49 48 29 26 87 54 12 18 21 20 26 20 67 55 65 61 76 74 156 156 ARF

pfam01388 2 0 0 0 1 1 0 0 0 2 6 3 0 3 2 3 2 1 4 4 8 6 8 6 25 19 ARID

smart00185 11 3 0 5 6 7 12 12 7 10 57 33 1 15 6 10 12 12 14 18 25 23 37 25 102 89 ARM

smart00570 1 0 0 0 0 0 0 0 0 0 3 2 0 1 2 2 1 1 4 2 4 2 5 3 10 5 AWS

pfam02137 2 0 0 0 0 1 1 2 0 0 1 1 0 1 1 1 1 0 5 1 4 3 4 4 13 11 A_deamin

pfam00928 7 0 0 4 3 7 8 7 4 3 8 5 1 3 4 4 6 5 6 7 7 5 5 7 21 16 Adap_comp_sub

pfam02883 2 0 0 1 0 1 2 1 0 1 4 3 0 4 2 3 3 2 2 1 4 4 8 3 14 14 Alpha_adaptinC2

pfam00266 6 0 0 1 2 6 2 7 7 7 6 4 1 5 4 5 5 4 5 8 6 7 5 13 9 7 Aminotran_5

pfam00023 96 0 0 11 16 11 24 38 16 40 66 62 0 10 77 18 8 11 147 105 313 160 188 153 642 539 Ank

pfam00191 6 0 0 0 0 0 0 0 0 0 27 14 0 0 7 5 0 0 18 10 14 36 22 16 91 88 Annexin

pfam00025 26 0 1 8 6 7 23 27 14 14 24 19 4 5 7 7 7 6 15 15 16 14 18 28 36 44 Arf

smart00105 12 0 0 2 3 3 6 12 7 4 17 16 2 6 5 4 6 5 9 8 8 12 16 14 41 28 ArfGap

pfam01412 12 0 0 2 3 3 6 12 7 4 17 16 2 6 5 4 6 5 9 8 8 12 16 14 41 28 ArfGap

pfam01603 1 0 0 0 0 1 0 0 0 1 8 7 1 2 1 1 1 1 3 2 5 2 6 3 8 16 B56

smart00721 2 0 0 0 0 0 0 0 0 0 5 0 0 4 4 4 3 3 9 5 7 6 5 4 25 25 BAR

pfam03114 1 0 0 0 0 0 0 0 0 0 0 0 0 2 4 3 3 2 1 1 2 2 1 1 8 6 BAR

smart00502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 3 0 2 5 3 13 10 BBC

smart00336 19 0 0 1 2 2 2 0 0 0 29 8 1 0 0 0 0 1 9 5 3 5 6 6 57 45 BBOX

smart00337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 2 3 4 18 16 BCL

pfam00653 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 1 2 0 3 3 17 10 8 33 21 47 BIR

smart00238 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 1 1 0 3 3 17 10 8 33 21 48 BIR

pfam00533 14 0 0 1 3 3 4 7 2 5 15 14 1 8 9 11 4 6 21 5 8 16 24 12 32 43 BRCT

smart00501 2 0 0 0 1 1 0 0 0 3 7 4 0 4 2 4 2 1 4 4 8 6 8 6 25 19 BRIGHT

smart00592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 3 4 1 13 8 BRK

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
smart00297 15 0 3 6 9 12 7 9 5 10 29 19 5 14 8 10 16 12 30 42 41 26 56 27 123 62 BROMO

smart00576 2 0 0 0 0 1 0 0 0 0 3 1 2 2 1 3 1 2 3 2 2 1 5 2 9 9 BTP

pfam00373 6 0 0 0 0 0 0 3 0 1 1 1 0 0 0 0 0 0 18 12 27 22 23 17 57 58 Band_41

pfam02138 8 0 0 1 1 2 6 5 4 3 6 6 0 1 1 1 1 1 4 3 5 6 5 6 19 8 Beach

pfam00439 14 0 3 6 9 12 5 6 5 8 27 17 5 12 7 7 15 13 30 40 40 25 50 25 114 56 Bromodomain

smart00239 38 0 0 3 6 15 16 22 16 21 150 92 2 15 15 17 17 13 76 65 111 59 78 76 277 230 C2

pfam00168 33 0 0 1 1 9 12 13 10 18 142 84 1 14 12 16 12 11 64 54 97 54 71 66 261 223 C2

smart00643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 2 3 4 16 15 C345C

smart00266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 3 6 0 7 6 CAD

pfam04218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 6 0 9 6 CENP-B_N

smart00033 40 0 0 1 0 0 2 4 2 3 29 15 3 9 7 8 7 7 51 40 70 37 76 31 142 127 CH

pfam05679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 4 8 4 6 12 21 18 CHGN

smart00298 9 0 0 2 3 3 0 0 1 9 15 15 2 10 17 11 4 3 22 11 16 11 24 10 44 39 CHROMO

pfam00878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 8 12 24 13 CIMR

pfam02487 1 0 0 0 0 0 2 2 2 0 0 0 0 1 1 2 1 1 4 4 4 2 4 0 16 8 CLN3

pfam00780 3 0 0 0 0 0 0 0 0 0 1 2 1 3 2 3 3 2 9 7 10 5 10 6 25 20 CNH

smart00036 2 0 0 0 0 0 0 2 0 1 1 2 1 4 2 3 3 2 9 6 10 5 10 7 27 21 CNH

pfam04516 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 0 1 0 3 5 5 3 18 10 CP2

pfam00313 0 0 0 1 1 2 7 3 2 2 4 2 0 0 0 0 0 0 6 5 6 7 13 4 25 22 CSD

smart00357 0 0 0 1 1 2 5 5 4 1 4 2 0 0 0 0 0 0 6 5 6 8 13 5 28 22 CSP

smart00041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 8 3 4 9 24 23 CT

smart00546 1 0 0 0 0 0 0 0 1 0 1 1 0 2 0 1 7 4 2 2 1 3 3 4 14 7 CUE

pfam02845 0 0 0 0 0 0 0 0 0 0 1 1 0 2 0 1 5 3 2 2 1 2 1 3 10 7 CUE

pfam02376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 6 7 4 5 2 16 20 CUT

smart00043 3 0 0 0 0 0 0 0 0 1 8 8 0 0 0 0 0 0 3 4 1 0 4 0 28 44 CY

pfam01049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 13 3 2 26 26 Cadherin_C

pfam01067 6 0 0 0 0 0 3 2 1 1 1 0 0 0 0 1 0 0 7 6 1 6 6 4 16 15 Calpain_III

pfam00385 3 0 0 1 1 1 0 0 0 7 3 2 1 4 2 4 1 1 8 4 6 5 10 4 18 19 Chromo

pfam01217 6 0 0 4 1 4 6 7 4 4 8 8 1 5 3 3 5 4 4 4 1 5 8 4 14 11 Clat_adaptor_s

pfam04594 4 0 0 2 0 2 1 4 2 2 2 1 1 1 2 3 2 2 3 2 0 3 4 6 9 4 Cnd1

pfam03712 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 4 3 6 5 5 12 4 7 Cu2_monoox_C

pfam00031 2 0 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 0 2 3 1 0 2 0 24 41 Cystatin

smart00021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 4 2 2 5 4 9 7 DAX

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
smart00537 2 0 0 1 1 1 2 3 0 0 0 0 0 0 0 0 0 0 9 6 3 4 9 10 18 28 DCX

pfam03607 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 6 2 2 6 8 15 27 DCX

pfam02862 4 0 0 1 1 2 0 0 0 0 2 0 0 2 2 3 1 2 5 5 7 3 7 4 11 13 DDHD

smart00005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 6 12 4 7 6 36 30 DEATH

pfam02141 7 0 0 0 0 0 1 4 1 2 5 5 0 1 2 2 0 0 6 5 6 9 11 5 38 31 DENN

smart00049 7 0 0 0 0 1 0 0 0 1 1 3 0 6 5 5 5 3 13 9 10 6 8 10 45 28 DEP

pfam00610 5 0 0 0 0 1 0 0 0 0 1 3 0 5 3 3 5 3 12 9 9 6 7 6 42 28 DEP

smart00050 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 0 0 0 4 4 6 7 9 3 31 42 DISIN

pfam00778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 4 2 2 5 4 9 7 DIX

smart00684 2 0 0 0 0 0 0 0 0 2 0 3 0 0 0 0 0 0 2 2 1 2 4 2 9 4 DM15

smart00195 28 0 0 3 3 10 28 37 19 16 19 14 1 5 9 9 9 8 58 43 28 23 41 28 110 89 DSPc

pfam00782 16 0 0 3 2 7 24 25 14 13 15 13 0 4 7 8 6 5 19 17 14 13 21 14 54 51 DSPc

pfam06327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 5 1 9 5 DUF1053

pfam04802 1 0 0 0 1 1 4 0 1 1 2 2 0 1 1 1 1 2 2 1 1 1 2 1 9 5 DUF625

pfam05885 1 0 0 0 0 0 0 0 0 1 1 1 0 0 0 0 0 0 3 4 5 4 4 6 13 12 DUF857

smart00695 5 0 0 1 0 1 1 0 1 0 6 2 0 2 1 1 1 1 3 2 4 3 6 3 13 12 DUSP

smart00572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 6 3 3 5 11 7 DZF

pfam00531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 5 11 4 7 3 34 38 Death

pfam06920 7 0 0 0 0 0 0 0 0 0 1 1 0 0 1 1 0 0 2 5 7 3 6 3 20 12 Ded_cyto

pfam00200 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 0 0 0 5 4 5 7 9 3 31 41 Disintegrin

pfam02319 3 0 0 0 1 0 0 0 0 3 10 9 2 0 0 0 0 0 4 4 3 2 5 6 13 26 E2F_TDP

pfam01448 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 6 3 6 7 10 2 17 13 ELM2

pfam01105 4 0 0 3 3 4 12 12 8 2 12 5 0 4 4 4 9 7 6 5 8 6 12 11 13 19 EMP24_GP25L

smart00615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 7 2 4 6 19 28 EPH_lbd

smart00413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 10 12 9 12 15 45 38 ETS

smart00479 6 0 0 1 2 4 14 12 9 8 14 14 1 7 8 6 6 6 10 14 11 10 14 11 22 23 EXOIII

pfam01404 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 7 2 4 6 19 28 Ephrin_lbd

pfam00178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 9 12 9 12 14 45 38 Ets

pfam00754 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 3 22 6 9 23 57 35 F5_F8_type_C

smart00231 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 2 22 5 9 19 55 34 FA58C

pfam00667 5 0 0 0 2 1 6 5 5 4 3 2 2 5 6 5 3 3 3 4 5 5 6 4 10 13 FAD_binding_1

pfam01839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 4 6 4 9 17 FG-GAP

smart00442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 2 2 4 8 29 30 FGF

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam00167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 1 3 8 28 30 FGF

smart00339 0 0 0 0 0 0 0 0 0 0 0 0 2 4 5 3 4 4 24 9 18 19 23 27 61 50 FH

smart00063 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 5 9 6 10 12 29 29 FRI

pfam01363 15 0 0 1 0 2 17 25 9 1 12 15 0 6 2 5 5 5 20 14 14 18 20 12 48 37 FYVE

smart00064 15 0 0 1 0 2 21 29 9 1 13 15 0 7 4 6 6 6 21 15 16 20 20 12 51 40 FYVE

pfam00210 0 0 0 0 0 0 0 0 0 2 5 0 1 0 0 0 0 0 2 2 2 2 5 3 11 7 Ferritin

pfam00038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 0 3 64 60 Filament

pfam01770 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 4 4 2 3 2 11 8 Folate_carrier

pfam00250 0 0 0 0 0 0 0 0 0 0 0 0 2 4 5 3 4 4 22 9 18 18 23 27 61 50 Fork_head

pfam02434 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 6 6 5 4 4 13 8 6 Fringe

pfam01534 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 4 7 7 5 8 16 16 Frizzled

pfam01392 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 5 14 7 11 13 32 34 Fz

pfam00631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 3 9 4 5 2 19 16 G-gamma

smart00243 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 5 1 7 1 7 4 14 7 GAS2

pfam02187 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 1 7 1 7 4 14 7 GAS2

pfam03127 0 0 0 0 0 0 0 0 0 0 5 5 0 0 0 0 0 0 3 2 1 0 3 2 9 6 GAT

pfam02841 0 0 0 0 0 0 0 0 0 0 2 4 0 0 0 0 0 0 0 0 1 0 0 0 9 17 GBP_C

smart00262 34 0 0 0 0 0 0 0 0 5 30 31 1 0 5 2 0 0 12 13 11 29 37 34 67 89 GEL

smart00224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 3 9 4 5 3 22 18 GGL

pfam03359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 2 1 4 2 9 12 GKAP

pfam02893 9 0 0 0 0 1 1 4 2 1 13 7 0 2 2 2 6 4 9 3 3 6 10 3 24 29 GRAM

smart00568 12 0 0 1 0 1 1 4 3 1 14 10 0 2 4 3 7 5 6 3 2 7 10 5 22 29 GRAM

smart00277 1 0 0 0 0 0 0 0 0 1 3 3 0 0 0 0 0 0 5 3 0 0 0 5 11 14 GRAN

pfam00735 0 0 0 0 0 0 0 0 0 1 0 0 3 7 7 8 7 8 3 3 4 4 9 5 28 18 GTP_CDC

pfam02709 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 3 3 2 2 5 20 12 9 Galactosyl_T_2

pfam00626 19 0 0 2 1 2 1 3 1 2 27 21 0 3 6 2 3 2 10 10 9 16 13 24 53 78 Gelsolin

pfam00852 11 0 0 0 0 0 0 2 1 1 3 1 0 0 0 0 0 0 4 5 4 2 8 45 11 6 Glyco_transf_10

pfam04666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 1 4 4 3 7 Glyco_transf_54

smart00390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 2 3 2 4 2 14 16 GoLoco

pfam00396 1 0 0 0 0 0 0 0 0 1 3 3 0 0 0 0 0 0 4 2 0 0 0 5 11 14 Granulin

pfam04670 2 0 0 0 2 1 1 4 2 0 0 0 0 2 2 3 2 2 3 2 3 2 2 2 8 7 Gtr1_RagA

smart00471 5 0 0 3 1 8 9 8 2 7 4 5 0 0 5 0 2 1 10 3 19 8 14 7 33 23 HDc

pfam02985 1 0 0 0 0 0 0 0 0 2 11 0 0 1 2 3 0 2 3 3 4 1 1 1 31 20 HEAT

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam00632 6 0 1 4 3 10 15 15 13 11 7 4 2 7 7 7 5 5 10 9 24 21 21 18 46 40 HECT

smart00119 7 0 2 5 5 12 16 16 17 14 7 4 2 8 8 7 6 5 10 9 26 22 22 19 52 42 HECTc

smart00398 3 0 0 0 3 1 0 3 0 5 13 6 0 4 7 8 7 5 17 13 21 19 34 21 84 80 HMG

pfam00505 2 0 0 0 3 1 0 0 0 4 13 4 0 3 5 7 7 5 15 11 23 19 31 16 69 65 HMG_box

pfam05622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 3 4 2 8 11 HOOK

pfam02793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 7 5 4 9 8 30 30 HRM

pfam02218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 8 3 19 13 HS1_rep

smart00120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 5 8 12 13 72 72 HX

pfam00045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 7 10 9 37 48 Hemopexin

smart00008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 7 5 4 8 9 36 30 HormR

pfam06462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 1 5 0 9 11 Hyd_WA

smart00409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 672 395 1086 522 849 262 2055 1110 IG

smart00407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 4 0 0 402 273 IGc1

smart00406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 2 30 28 29 5 455 367 IGv

pfam00478 4 0 0 1 1 2 3 4 3 3 3 4 0 4 2 2 5 2 5 3 4 1 3 3 12 5 IMPDH

smart00187 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 2 7 2 3 6 13 14 INB

pfam01007 0 0 0 0 1 2 0 0 0 3 0 0 0 0 0 0 0 0 3 3 6 7 7 4 19 17 IRK

pfam02174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 4 7 5 3 20 12 IRS

smart00191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 4 2 14 18 28 66 79 Int_alpha

smart00558 5 0 1 1 0 3 2 3 3 4 19 10 0 4 4 4 4 3 14 11 13 10 14 8 35 33 JmjC

pfam02373 6 0 1 2 0 3 2 3 3 6 19 13 0 6 5 5 4 3 14 11 15 12 14 9 39 41 JmjC

pfam02149 3 0 0 0 0 0 0 0 0 1 2 6 0 1 1 1 2 2 5 3 4 2 3 2 11 6 KA1

smart00130 0 0 0 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 4 3 6 2 2 37 90 36 KR

pfam00051 0 0 0 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 3 2 6 2 2 35 89 36 Kringle

pfam02828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 4 0 2 4 2 11 13 L27

smart00569 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 3 4 3 5 2 19 18 L27

pfam01273 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 0 0 0 5 6 0 0 0 2 17 11 LBP_BPI_CETP

pfam03815 0 0 0 6 6 1 0 0 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 22 13 10 LCCL

smart00603 0 0 0 7 6 1 0 0 0 0 0 0 0 0 2 1 1 1 0 0 0 0 0 23 13 10 LCCL

pfam04791 5 0 0 0 1 1 4 2 3 3 5 5 0 1 2 1 0 0 4 4 4 3 4 6 23 11 LMBR1

smart00082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 16 42 25 29 14 91 78 LRRCT

smart00013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 11 16 4 3 8 31 28 LRRNT

pfam01462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 1 3 1 3 9 6 LRRNT

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
smart00368 2 0 0 0 0 0 5 5 3 3 2 0 0 0 0 0 0 0 2 1 2 1 1 2 12 10 LRR_RI

smart00369 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 1 2 0 5 4 8 9 20 16 LRR_TYP

pfam00753 9 0 0 4 1 3 8 8 6 4 13 9 3 7 12 7 4 1 12 11 7 10 13 14 23 18 Lactamase_B

smart00282 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 47 41 107 76 85 31 199 159 LamG

smart00560 2 0 0 0 1 0 1 4 0 1 0 0 0 0 0 0 0 0 0 0 2 1 2 1 10 13 LamGL

smart00136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 6 5 8 5 8 8 30 19 LamNT

pfam00053 2 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 40 32 49 27 51 42 135 88 Laminin_EGF

pfam00055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 5 8 5 8 8 30 19 Laminin_N

pfam01299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 5 2 9 9 Lamp

pfam00061 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 5 4 4 13 4 2 38 49 Lipocalin

pfam00629 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 2 3 5 3 9 52 42 26 MAM

smart00137 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 8 8 3 3 9 55 42 26 MAM

pfam01284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 4 2 3 2 4 25 17 MARVEL

smart00391 0 0 0 0 0 0 0 0 0 0 8 5 0 0 0 0 0 0 2 3 2 6 8 3 14 14 MBD

smart00561 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 15 15 9 16 9 59 44 MBT

pfam02820 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 10 14 9 16 9 55 41 MBT

pfam01853 2 0 0 1 2 2 4 6 4 1 2 0 2 2 3 3 3 3 5 4 6 5 7 4 12 8 MOZ_SAS

pfam00994 2 0 0 0 0 0 0 0 0 2 3 2 0 0 3 2 1 1 3 3 1 4 2 5 8 3 MoCF_biosynth

pfam06017 7 0 0 0 0 0 2 5 0 0 1 1 0 1 1 1 2 2 2 2 2 3 5 4 13 12 Myosin_tail_2

pfam00956 2 0 0 2 1 3 2 2 3 4 7 8 0 3 2 2 1 1 3 4 2 5 5 3 17 16 NAP

pfam04095 1 0 0 1 0 2 1 1 1 1 2 3 0 1 2 1 1 1 3 1 2 4 3 1 11 5 NAPRTase

smart00562 3 0 0 2 2 3 8 6 3 6 6 2 1 1 1 1 1 1 3 1 7 4 6 10 15 18 NDK

smart00227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 3 4 1 4 3 96 62 NEBU

smart00539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 4 2 3 5 19 12 NIDO

pfam01759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 2 2 4 14 12 NTR

pfam00939 0 0 0 0 0 0 1 0 2 6 5 0 0 1 2 1 1 2 4 5 8 6 8 13 15 6 Na_sulph_symp

pfam06512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 2 1 2 19 10 Na_trans_assoc

pfam03593 2 0 1 4 1 4 4 3 3 4 4 3 1 1 1 1 0 0 1 1 2 1 2 5 6 9 Nuclear_move

smart00284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 1 2 8 26 13 OLF

pfam02191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 1 2 8 24 13 OLF

pfam01237 11 0 0 2 2 2 0 2 0 4 13 2 0 6 5 5 7 6 7 4 6 6 8 6 24 17 Oxysterol_BP

pfam01089 3 0 0 1 1 2 2 2 1 1 2 1 0 1 4 1 1 1 2 2 4 5 5 2 10 5 P5CR

smart00085 0 0 0 0 0 0 0 0 0 0 5 1 0 0 0 0 0 0 2 1 4 6 6 6 13 17 PA2c

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam01569 5 0 0 0 0 1 3 2 2 0 7 6 1 3 6 4 6 7 9 6 0 6 12 6 20 21 PAP2

smart00285 4 0 0 0 0 0 0 0 0 0 12 8 0 2 2 2 4 3 10 7 5 6 9 4 25 15 PBD

smart00018 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 2 1 1 0 21 11 9 PD

smart00141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 2 1 5 1 15 15 PDGF

smart00228 0 0 0 2 0 3 2 10 5 4 7 15 1 0 2 0 2 2 95 75 124 118 141 101 437 321 PDZ

pfam00595 0 0 0 1 0 2 0 1 2 2 0 4 0 0 0 0 1 0 72 58 93 94 114 72 343 277 PDZ

smart00233 63 0 0 3 5 7 19 26 13 4 18 12 2 17 14 13 15 14 61 48 66 67 109 81 372 324 PH

pfam00169 47 0 0 3 3 4 16 20 7 3 13 7 1 14 12 11 11 12 43 34 47 52 76 63 284 242 PH

smart00249 10 0 1 6 7 9 2 3 0 26 69 53 1 22 18 15 16 10 59 34 42 67 79 53 168 131 PHD

pfam00628 7 0 0 5 3 6 0 1 0 22 38 34 1 16 16 12 13 7 36 22 32 50 60 38 121 87 PHD

pfam05682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 4 0 5 2 5 7 11 PHK_AB

smart00142 6 0 0 0 0 0 2 2 0 0 1 1 0 1 1 1 1 1 6 4 4 2 4 3 10 11 PI3K_C2

pfam00792 5 0 0 0 0 0 2 3 0 0 1 1 0 1 1 1 1 1 6 4 4 2 4 4 11 11 PI3K_C2

smart00144 4 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 2 2 2 1 2 2 9 8 PI3K_rbd

pfam00640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21 14 14 16 15 12 65 48 PID

smart00088 12 0 0 6 7 7 8 12 8 8 13 14 4 11 10 11 7 8 13 11 14 12 15 10 21 16 PINT

pfam01735 0 0 0 0 0 0 0 0 0 0 0 0 0 5 3 2 6 5 0 0 0 0 0 5 8 6 PLA2_B

smart00250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 1 0 0 4 31 223 182 PLEC

smart00352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 4 8 4 7 2 18 28 POU

smart00462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32 18 22 21 25 15 90 56 PTB

smart00310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 8 7 5 3 20 12 PTBI

smart00159 1 0 0 0 1 0 0 2 0 1 0 2 0 0 0 0 0 0 1 1 3 4 4 4 18 20 PTX

pfam00855 2 0 0 0 0 1 2 3 1 1 12 8 0 3 1 0 2 2 2 1 2 2 12 11 52 29 PWWP

smart00293 3 0 0 0 0 1 2 3 2 3 12 8 0 3 1 1 2 2 2 1 2 3 12 12 52 31 PWWP

pfam00787 6 0 0 0 1 1 3 6 3 3 9 5 1 11 7 11 12 13 13 10 20 15 18 23 60 54 PX

smart00312 6 0 0 0 2 1 3 7 3 3 8 6 1 11 8 10 14 14 14 10 18 15 17 22 58 53 PX

pfam01562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 5 4 9 5 48 57 Pep_M12B_propep

pfam03416 4 0 0 0 1 2 3 3 2 2 2 3 0 1 1 1 1 1 3 4 3 3 3 2 13 8 Peptidase_C54

pfam00413 0 0 0 0 0 0 0 0 0 0 5 1 0 0 0 0 0 0 4 4 2 3 4 7 33 31 Peptidase_M10

pfam03933 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 0 0 2 2 2 3 4 6 21 28 Peptidase_M10_N

pfam03036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 4 4 2 8 13 Perilipin

pfam00068 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 1 0 1 1 6 13 15 Phospholip_A2_1

pfam00157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 4 8 4 7 2 18 28 Pou

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam05044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 3 2 4 2 10 4 Prox1

smart00393 3 0 0 0 0 1 5 3 2 0 6 4 0 2 4 4 4 2 2 3 0 2 6 6 11 16 R3H

pfam01424 1 0 0 0 0 0 1 2 1 0 2 1 0 3 1 3 3 2 2 3 0 2 6 4 11 15 R3H

pfam00788 3 0 0 0 0 0 0 0 0 0 0 0 0 2 2 2 1 1 24 14 23 18 22 7 52 41 RA

pfam00415 10 0 0 0 2 1 0 2 1 0 11 7 1 0 0 0 0 0 3 3 11 4 3 9 26 23 RCC1

pfam02257 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1 2 1 2 0 3 3 4 11 12 RFX_DNA_binding

smart00315 11 0 0 0 0 0 0 0 0 0 1 0 0 2 4 5 5 3 25 18 12 14 21 29 63 48 RGS

pfam00554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 3 5 3 13 18 RHD

smart00450 8 0 0 0 0 2 16 17 15 19 19 13 2 8 10 10 10 10 18 15 2 8 11 15 33 26 RHOD

smart00394 0 0 0 0 0 1 1 1 1 1 0 0 0 1 0 0 1 0 2 2 2 3 2 4 15 14 RIIa

smart00582 4 0 0 1 4 1 2 1 0 3 10 4 1 4 3 3 3 3 7 5 7 9 8 8 17 14 RPR

smart00361 8 0 0 4 4 6 6 2 2 5 23 12 3 4 7 8 3 7 13 14 12 7 20 13 40 38 RRM_1

smart00593 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 6 4 8 11 6 25 17 RUN

pfam02759 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 5 4 6 10 6 28 21 RUN

pfam04712 0 0 0 2 0 1 4 4 4 4 0 0 0 0 0 0 0 0 0 0 0 1 2 3 4 8 Radial_spoke

pfam00638 2 0 0 2 1 1 1 1 1 1 6 3 1 3 3 2 3 3 5 2 2 3 9 7 18 9 Ran_BP1

pfam00616 11 0 0 0 0 0 0 0 0 0 0 0 1 2 3 4 3 3 3 3 5 5 7 6 23 18 RasGAP

smart00323 12 0 0 0 0 1 0 0 0 0 0 0 0 2 3 4 4 3 4 3 6 5 10 7 33 31 RasGAP

smart00324 45 0 0 1 1 1 1 1 1 0 9 5 3 10 9 10 12 11 32 24 33 23 36 28 120 91 RhoGAP

pfam00620 44 0 0 1 1 1 1 1 1 0 9 5 3 10 7 8 11 9 31 23 33 22 35 28 112 89 RhoGAP

smart00325 48 0 1 0 0 0 0 0 0 0 0 0 1 8 5 5 5 4 34 21 39 27 53 30 117 92 RhoGEF

pfam00621 47 0 1 0 0 0 0 0 0 0 0 0 1 7 6 5 4 2 30 21 37 25 46 28 112 89 RhoGEF

pfam00581 4 0 0 0 0 2 9 12 7 14 15 8 2 8 7 6 10 7 10 9 1 7 8 9 30 24 Rhodanese

smart00454 9 0 0 1 1 0 4 4 0 5 7 5 0 4 5 5 1 1 36 25 20 31 40 29 136 125 SAM

pfam00536 4 0 0 0 1 0 4 0 0 1 5 2 0 4 4 3 1 1 24 19 12 19 28 19 91 91 SAM

smart00251 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 10 5 10 10 22 20 SAM_PNT

pfam02198 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 9 4 9 10 19 16 SAM_PNT

smart00258 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 4 3 2 1 1 3 9 14 SAND

pfam01342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 3 2 1 1 3 9 14 SAND

smart00178 41 0 1 9 7 10 24 29 18 16 39 30 7 8 9 10 15 11 38 35 40 31 36 48 72 82 SAR

smart00200 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 5 0 0 0 1 30 18 SEA

pfam01390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 4 0 0 0 1 21 17 SEA

smart00553 1 0 0 1 0 1 2 0 0 0 4 2 0 1 1 1 1 1 2 1 1 1 3 2 10 7 SEP

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
smart00317 21 0 0 6 6 16 41 40 24 29 40 22 1 10 15 18 7 6 37 26 29 41 41 18 74 59 SET

pfam00017 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 50 32 49 34 46 48 149 149 SH2

smart00252 11 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 1 1 73 47 53 38 48 51 159 160 SH2

smart00326 31 0 0 0 0 0 6 10 6 0 3 3 0 21 25 24 28 26 105 88 131 86 179 103 360 332 SH3

pfam00018 25 0 0 0 0 0 5 10 5 0 2 3 0 21 18 21 27 22 73 74 110 74 148 87 309 285 SH3

smart00253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 4 4 15 6 29 31 SOCS

pfam00622 8 0 0 1 0 3 13 17 8 8 7 1 0 3 2 3 3 3 15 32 35 17 25 16 117 80 SPRY

smart00449 8 1 0 1 0 4 19 23 8 8 7 1 0 3 3 3 4 3 15 33 36 18 25 17 120 84 SPRY

smart00202 0 0 0 2 2 0 0 0 0 49 0 0 0 0 0 0 0 0 4 4 8 8 16 9 155 109 SR

pfam00530 0 0 0 2 2 0 0 0 0 23 0 0 0 0 0 0 0 0 2 2 6 8 12 8 143 100 SRCR

pfam03365 1 0 0 0 0 0 1 2 1 1 1 4 1 2 1 1 2 2 1 1 0 3 4 3 15 6 STAG

pfam01369 6 0 0 0 1 5 5 4 4 2 7 6 1 6 4 4 5 4 6 5 12 5 10 6 23 18 Sec7

pfam01403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 5 15 7 14 11 45 40 Sema

smart00630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 7 16 7 15 12 51 44 Sema

pfam02750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 3 4 4 0 4 6 Synapsin_C

smart00164 33 0 0 11 8 15 20 29 13 11 25 13 3 13 12 11 10 9 26 22 39 25 38 30 85 57 TBC

pfam00566 30 0 0 5 8 10 7 20 4 9 23 10 3 11 12 10 8 7 21 15 28 20 34 23 66 45 TBC

smart00706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 4 0 5 4 TECPR

smart00510 1 0 0 2 1 1 1 2 1 2 6 4 1 1 2 1 1 2 1 1 3 3 3 2 10 8 TFS2M

pfam03299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 1 2 1 2 1 10 7 TF_AP-2

smart00204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 5 16 7 9 11 37 41 TGFB

pfam00019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 5 16 7 9 11 40 44 TGF_beta

pfam00688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 4 5 7 8 21 24 TGFb_propeptide

smart00460 4 0 0 0 0 0 0 0 0 1 2 0 0 3 2 3 2 2 2 2 4 4 6 6 15 16 TGc

pfam04201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 7 0 13 7 TPD52

smart00210 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 7 2 11 10 4 9 43 43 TSPN

pfam05735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 1 1 4 5 7 TSP_C

pfam02210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 2 8 3 2 9 30 36 TSP_N

smart00211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 11 12 12 10 11 30 35 TY

pfam00086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 4 11 7 4 10 29 33 Thyroglobulin_1

pfam06309 2 0 0 2 0 3 4 6 4 1 5 8 0 1 2 1 1 2 3 2 0 3 1 2 14 8 Torsin

pfam00927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 3 4 1 23 30 Transglut_C

pfam01841 4 0 0 0 0 0 0 0 0 0 1 0 0 1 1 1 1 1 1 1 1 3 5 4 15 16 Transglut_core

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam04906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 4 1 3 6 0 16 11 Tweety

pfam00627 3 0 0 0 0 4 2 2 1 2 11 7 0 3 3 1 4 3 1 2 2 6 11 6 21 13 UBA

pfam00443 37 0 0 12 9 21 31 38 20 20 58 25 5 25 20 22 31 29 47 34 42 37 50 45 122 103 UCH

pfam01170 1 0 0 1 1 1 1 2 1 0 2 3 0 2 2 3 2 2 4 5 4 1 2 3 9 6 UPF0020

pfam03006 3 0 0 0 0 1 2 4 3 2 8 6 1 2 2 2 5 5 6 6 3 5 5 6 13 11 UPF0073

pfam04615 1 0 0 0 1 1 1 3 1 1 4 2 1 3 2 2 3 3 2 2 0 3 3 2 5 9 Utp14

pfam00790 1 0 0 0 0 0 1 2 1 2 8 7 0 5 4 4 4 3 6 5 4 5 5 4 17 16 VHS

smart00288 1 0 0 0 0 0 1 2 2 2 10 8 0 5 4 4 5 3 6 5 4 5 5 4 17 16 VHS

smart00167 8 0 0 0 1 1 1 3 1 0 2 3 1 2 2 3 2 2 4 4 2 2 3 3 13 16 VPS9

smart00214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 7 6 15 5 33 37 VWC

pfam00093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 11 11 6 34 34 VWC

smart00215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 0 3 9 17 15 VWC_out

smart00217 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 2 5 2 4 0 8 7 WAP

pfam00400 186 4 5 41 30 56 113 104 70 135 227 192 26 130 165 118 87 89 154 138 214 220 240 199 430 395 WD40

smart00320 368 6 8 82 68 109 246 247 141 246 465 364 57 233 259 221 161 162 293 264 424 398 460 398 813 702 WD40

smart00456 5 0 0 4 1 5 13 17 7 9 11 7 1 10 7 8 8 7 38 27 50 41 43 31 119 83 WW

pfam00397 4 0 0 4 1 2 10 8 5 6 6 3 0 9 3 5 6 6 21 17 38 36 31 20 97 66 WW

smart00678 7 0 0 0 2 0 2 2 1 0 1 0 0 0 0 0 0 0 5 2 1 2 5 2 17 14 WWE

pfam02825 0 0 0 0 2 0 0 0 0 0 2 1 0 0 0 0 0 0 5 2 1 2 7 2 16 11 WWE

pfam04893 3 0 0 0 0 2 5 5 3 1 4 3 1 3 4 3 2 2 7 6 3 2 3 5 10 11 Yip1

smart00355 0 0 0 0 0 0 0 0 0 0 3 0 0 3 7 2 1 4 2 2 2 6 5 4 30 30 ZnF_C2H2

smart00451 6 0 0 2 2 3 0 0 2 1 15 2 0 4 5 4 5 5 6 3 6 13 16 8 41 28 ZnF_U1

smart00290 5 0 0 3 2 2 5 4 3 1 8 5 1 7 0 1 4 4 5 6 8 7 7 5 14 16 ZnF_UBP

smart00291 5 0 0 2 0 2 4 3 3 1 11 10 0 3 9 3 2 2 12 8 17 13 19 12 33 21 ZnF_ZZ

smart00014 5 0 0 0 0 1 4 2 2 0 5 6 1 4 5 3 6 7 7 6 0 6 9 5 23 22 acidPPc

pfam03455 2 0 0 0 0 0 0 0 0 0 1 0 0 1 1 1 0 0 6 5 7 9 10 3 35 25 dDENN

pfam00047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79 34 231 111 110 35 496 319 ig

pfam03456 5 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 0 0 6 5 6 8 9 4 33 28 uDENN

pfam00110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 5 19 13 14 11 24 29 wnt

pfam00096 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 1 5 0 1 1 1 2 0 16 6 zf-C2H2

pfam01530 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 15 5 4 6 39 42 zf-C2HC

pfam02008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 3 1 4 3 7 13 zf-CXXC

pfam00641 0 0 0 0 0 0 0 2 1 0 2 0 0 1 2 1 2 2 0 1 0 0 4 0 17 10 zf-RanBP

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam02148 5 0 0 2 1 1 5 4 3 1 7 5 1 4 1 0 3 3 5 6 7 6 6 5 13 15 zf-UBP

At least one chordate within top2:

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam00244 1 0 0 2 1 4 2 4 2 3 15 7 1 2 3 3 2 2 4 2 9 7 3 9 9 11 14-3-3

smart00101 1 0 0 3 1 4 2 4 2 3 15 7 1 2 3 3 2 2 4 2 9 7 3 9 9 11 14_3_3

pfam05902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 1 0 2 2 0 7 10 4_1_CTD

pfam00001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177 131 210 103 133 142 934 1684 7tm_1

pfam01661 3 0 0 2 0 2 2 3 0 3 4 2 0 0 2 1 0 0 1 1 2 3 1 25 15 12 A1pp

smart00506 3 0 0 2 0 3 2 2 1 3 4 2 0 0 3 1 2 2 1 1 2 5 6 31 15 14 A1pp

pfam00207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 3 8 23 17 5 32 14 A2M

smart00608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 5 6 5 3 36 48 ACR

smart00268 57 0 0 17 9 18 13 22 14 10 21 21 4 13 13 13 17 17 13 14 18 26 17 34 44 37 ACTIN

smart00552 2 0 0 0 0 1 1 2 1 0 1 2 0 1 1 1 1 1 5 1 4 3 4 4 13 11 ADEAMc

pfam05110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 2 2 2 23 32 AF-4

pfam04548 1 0 0 0 0 0 0 0 0 0 22 8 0 0 0 0 0 0 0 0 0 0 0 0 13 10 AIG1

pfam00501 35 0 0 17 8 13 13 23 19 11 51 41 3 13 93 36 11 10 39 39 42 46 42 33 72 45 AMP-binding

smart00248 79 0 0 8 12 15 23 44 20 44 75 76 1 9 76 22 7 14 126 90 295 151 190 146 637 521 ANK

smart00335 5 0 0 0 0 0 0 0 0 0 27 16 0 0 8 5 0 0 18 10 18 36 22 15 92 84 ANX

smart00223 1 0 0 0 0 17 0 0 0 1 0 3 0 0 0 0 0 0 1 0 0 0 0 0 8 12 APPLE

smart00177 91 1 1 17 10 22 49 48 29 26 87 54 12 18 21 20 26 20 67 55 65 61 76 74 156 156 ARF

pfam01388 2 0 0 0 1 1 0 0 0 2 6 3 0 3 2 3 2 1 4 4 8 6 8 6 25 19 ARID

smart00185 11 3 0 5 6 7 12 12 7 10 57 33 1 15 6 10 12 12 14 18 25 23 37 25 102 89 ARM

pfam02807 0 0 0 0 0 0 3 1 0 0 0 0 0 0 0 0 0 0 6 3 4 4 7 10 4 4 ATP-gua_PtransN

smart00570 1 0 0 0 0 0 0 0 0 0 3 2 0 1 2 2 1 1 4 2 4 2 5 3 10 5 AWS

pfam02137 2 0 0 0 0 1 1 2 0 0 1 1 0 1 1 1 1 0 5 1 4 3 4 4 13 11 A_deamin

pfam00962 5 0 0 3 1 3 8 9 9 3 3 2 0 4 6 5 5 4 7 6 10 8 18 6 11 9 A_deaminase

pfam00022 55 0 0 11 8 10 12 21 11 9 19 20 2 12 11 10 11 14 13 13 18 22 16 31 42 35 Actin

pfam00928 7 0 0 4 3 7 8 7 4 3 8 5 1 3 4 4 6 5 6 7 7 5 5 7 21 16 Adap_comp_sub

pfam02883 2 0 0 1 0 1 2 1 0 1 4 3 0 4 2 3 3 2 2 1 4 4 8 3 14 14 Alpha_adaptinC2

pfam00266 6 0 0 1 2 6 2 7 7 7 6 4 1 5 4 5 5 4 5 8 6 7 5 13 9 7 Aminotran_5

pfam00909 7 0 0 0 0 0 0 2 0 12 6 11 0 4 5 4 3 3 7 10 5 2 2 5 30 7 Ammonium_transp

pfam00023 96 0 0 11 16 11 24 38 16 40 66 62 0 10 77 18 8 11 147 105 313 160 188 153 642 539 Ank

pfam00191 6 0 0 0 0 0 0 0 0 0 27 14 0 0 7 5 0 0 18 10 14 36 22 16 91 88 Annexin

pfam00025 26 0 1 8 6 7 23 27 14 14 24 19 4 5 7 7 7 6 15 15 16 14 18 28 36 44 Arf

smart00105 12 0 0 2 3 3 6 12 7 4 17 16 2 6 5 4 6 5 9 8 8 12 16 14 41 28 ArfGap

pfam01412 12 0 0 2 3 3 6 12 7 4 17 16 2 6 5 4 6 5 9 8 8 12 16 14 41 28 ArfGap

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam06456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 3 8 3 4 3 11 6 Arfaptin

pfam01731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 5 2 0 0 0 0 4 7 Arylesterase

pfam01603 1 0 0 0 0 1 0 0 0 1 8 7 1 2 1 1 1 1 3 2 5 2 6 3 8 16 B56

smart00721 2 0 0 0 0 0 0 0 0 0 5 0 0 4 4 4 3 3 9 5 7 6 5 4 25 25 BAR

pfam03114 1 0 0 0 0 0 0 0 0 0 0 0 0 2 4 3 3 2 1 1 2 2 1 1 8 6 BAR

smart00502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 3 0 2 5 3 13 10 BBC

smart00336 19 0 0 1 2 2 2 0 0 0 29 8 1 0 0 0 0 1 9 5 3 5 6 6 57 45 BBOX

smart00337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 2 3 4 18 16 BCL

pfam00653 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 1 2 0 3 3 17 10 8 33 21 47 BIR

smart00238 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 1 1 0 3 3 17 10 8 33 21 48 BIR

pfam03493 3 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 3 6 18 4 5 3 8 5 BK_channel_a

pfam00533 14 0 0 1 3 3 4 7 2 5 15 14 1 8 9 11 4 6 21 5 8 16 24 12 32 43 BRCT

smart00501 2 0 0 0 1 1 0 0 0 3 7 4 0 4 2 4 2 1 4 4 8 6 8 6 25 19 BRIGHT

smart00592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 3 4 1 13 8 BRK

smart00297 15 0 3 6 9 12 7 9 5 10 29 19 5 14 8 10 16 12 30 42 41 26 56 27 123 62 BROMO

smart00576 2 0 0 0 0 1 0 0 0 0 3 1 2 2 1 3 1 2 3 2 2 1 5 2 9 9 BTP

pfam00373 6 0 0 0 0 0 0 3 0 1 1 1 0 0 0 0 0 0 18 12 27 22 23 17 57 58 Band_41

pfam02138 8 0 0 1 1 2 6 5 4 3 6 6 0 1 1 1 1 1 4 3 5 6 5 6 19 8 Beach

pfam04775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 7 0 0 0 5 4 11 Bile_Hydr_Trans

pfam02785 3 0 0 1 1 3 4 2 3 2 4 1 0 2 6 3 4 4 6 11 5 4 6 3 9 6 Biotin_carb_C

pfam00364 7 0 0 2 1 10 9 9 7 7 17 11 0 5 6 6 5 7 7 7 8 6 9 10 19 10 Biotin_lipoyl

pfam00439 14 0 3 6 9 12 5 6 5 8 27 17 5 12 7 7 15 13 30 40 40 25 50 25 114 56 Bromodomain

smart00239 38 0 0 3 6 15 16 22 16 21 150 92 2 15 15 17 17 13 76 65 111 59 78 76 277 230 C2

pfam00168 33 0 0 1 1 9 12 13 10 18 142 84 1 14 12 16 12 11 64 54 97 54 71 66 261 223 C2

smart00643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 2 3 4 16 15 C345C

pfam01413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 8 36 6 8 4 21 14 C4

smart00111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 8 36 6 8 4 21 14 C4

smart00266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 3 6 0 7 6 CAD

pfam04218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 6 0 9 6 CENP-B_N

smart00033 40 0 0 1 0 0 2 4 2 3 29 15 3 9 7 8 7 7 51 40 70 37 76 31 142 127 CH

pfam05679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 4 8 4 6 12 21 18 CHGN

pfam07452 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 4 0 4 3 6 3 CHRD

smart00298 9 0 0 2 3 3 0 0 1 9 15 15 2 10 17 11 4 3 22 11 16 11 24 10 44 39 CHROMO

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam00878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 8 12 24 13 CIMR

smart00299 11 0 0 5 5 7 10 14 7 8 24 5 1 8 9 10 8 7 9 10 4 9 11 11 16 18 CLH

pfam02487 1 0 0 0 0 0 2 2 2 0 0 0 0 1 1 2 1 1 4 4 4 2 4 0 16 8 CLN3

pfam00780 3 0 0 0 0 0 0 0 0 0 1 2 1 3 2 3 3 2 9 7 10 5 10 6 25 20 CNH

smart00036 2 0 0 0 0 0 0 2 0 1 1 2 1 4 2 3 3 2 9 6 10 5 10 7 27 21 CNH

pfam04516 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 0 1 0 3 5 5 3 18 10 CP2

pfam00313 0 0 0 1 1 2 7 3 2 2 4 2 0 0 0 0 0 0 6 5 6 7 13 4 25 22 CSD

smart00357 0 0 0 1 1 2 5 5 4 1 4 2 0 0 0 0 0 0 6 5 6 8 13 5 28 22 CSP

smart00041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 8 3 4 9 24 23 CT

smart00546 1 0 0 0 0 0 0 0 1 0 1 1 0 2 0 1 7 4 2 2 1 3 3 4 14 7 CUE

pfam02845 0 0 0 0 0 0 0 0 0 0 1 1 0 2 0 1 5 3 2 2 1 2 1 3 10 7 CUE

pfam02376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 6 7 4 5 2 16 20 CUT

smart00043 3 0 0 0 0 0 0 0 0 1 8 8 0 0 0 0 0 0 3 4 1 0 4 0 28 44 CY

pfam02743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 2 12 5 7 3 11 5 Cache

pfam01049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 13 3 2 26 26 Cadherin_C

pfam01067 6 0 0 0 0 0 3 2 1 1 1 0 0 0 0 1 0 0 7 6 1 6 6 4 16 15 Calpain_III

pfam00385 3 0 0 1 1 1 0 0 0 7 3 2 1 4 2 4 1 1 8 4 6 5 10 4 18 19 Chromo

pfam01217 6 0 0 4 1 4 6 7 4 4 8 8 1 5 3 3 5 4 4 4 1 5 8 4 14 11 Clat_adaptor_s

pfam04594 4 0 0 2 0 2 1 4 2 2 2 1 1 1 2 3 2 2 3 2 0 3 4 6 9 4 Cnd1

pfam04145 1 0 0 1 1 2 0 0 0 1 3 0 0 3 3 4 2 1 11 5 2 2 6 7 3 2 Ctr

pfam03712 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 4 3 6 5 5 12 4 7 Cu2_monoox_C

pfam01082 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 4 3 6 9 6 13 4 7 Cu2_monooxygen

pfam02727 0 0 0 0 0 0 0 0 0 0 8 4 0 2 3 1 0 0 0 0 0 0 0 0 3 7 Cu_amine_oxidN2

pfam00839 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 20 11 14 6 7 5 29 11 Cys_rich_FGFR

pfam00031 2 0 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 0 2 3 1 0 2 0 24 41 Cystatin

pfam03982 1 0 1 0 0 2 3 6 1 5 7 5 0 1 2 1 1 1 5 5 2 2 3 1 13 4 DAGAT

smart00021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 4 2 2 5 4 9 7 DAX

smart00537 2 0 0 1 1 1 2 3 0 0 0 0 0 0 0 0 0 0 9 6 3 4 9 10 18 28 DCX

pfam03607 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 6 2 2 6 8 15 27 DCX

pfam03184 0 0 0 0 0 0 0 0 0 2 1 0 0 3 24 1 2 1 12 4 0 8 0 2 18 12 DDE

pfam02862 4 0 0 1 1 2 0 0 0 0 2 0 0 2 2 3 1 2 5 5 7 3 7 4 11 13 DDHD

pfam06733 2 0 0 2 2 5 6 7 3 1 6 3 3 2 2 2 2 2 6 11 4 3 4 5 8 5 DEAD_2

smart00005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 6 12 4 7 6 36 30 DEATH

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam02141 7 0 0 0 0 0 1 4 1 2 5 5 0 1 2 2 0 0 6 5 6 9 11 5 38 31 DENN

smart00049 7 0 0 0 0 1 0 0 0 1 1 3 0 6 5 5 5 3 13 9 10 6 8 10 45 28 DEP

pfam00610 5 0 0 0 0 1 0 0 0 0 1 3 0 5 3 3 5 3 12 9 9 6 7 6 42 28 DEP

smart00488 3 1 0 5 3 5 8 9 4 3 7 3 5 3 3 4 3 3 9 15 5 3 5 8 12 9 DEXDc2

smart00050 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 0 0 0 4 4 6 7 9 3 31 42 DISIN

pfam00778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 4 2 2 5 4 9 7 DIX

smart00684 2 0 0 0 0 0 0 0 0 2 0 3 0 0 0 0 0 0 2 2 1 2 4 2 9 4 DM15

smart00692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 4 1 10 36 12 11 7 DM3

pfam00930 1 0 0 0 0 1 1 2 1 0 1 1 0 2 3 1 3 2 5 3 28 14 13 8 22 8 DPPIV_N

smart00195 28 0 0 3 3 10 28 37 19 16 19 14 1 5 9 9 9 8 58 43 28 23 41 28 110 89 DSPc

pfam00782 16 0 0 3 2 7 24 25 14 13 15 13 0 4 7 8 6 5 19 17 14 13 21 14 54 51 DSPc

pfam06327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 5 1 9 5 DUF1053

pfam06650 5 0 0 0 0 1 0 1 0 2 3 1 0 2 1 1 1 1 5 3 0 3 2 2 9 4 DUF1162

pfam04802 1 0 0 0 1 1 4 0 1 1 2 2 0 1 1 1 1 2 2 1 1 1 2 1 9 5 DUF625

pfam04819 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 0 0 0 0 0 0 0 3 4 9 DUF716

pfam05705 7 0 0 0 0 0 0 0 0 0 4 3 0 0 3 1 0 0 4 3 4 4 4 2 2 4 DUF829

pfam05885 1 0 0 0 0 0 0 0 0 1 1 1 0 0 0 0 0 0 3 4 5 4 4 6 13 12 DUF857

pfam06119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 8 4 2 3 2 13 7 DUF958

smart00695 5 0 0 1 0 1 1 0 1 0 6 2 0 2 1 1 1 1 3 2 4 3 6 3 13 12 DUSP

smart00572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 6 3 3 5 11 7 DZF

pfam00531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 5 11 4 7 3 34 38 Death

pfam06920 7 0 0 0 0 0 0 0 0 0 1 1 0 0 1 1 0 0 2 5 7 3 6 3 20 12 Ded_cyto

pfam00200 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 0 0 0 5 4 5 7 9 3 31 41 Disintegrin

pfam02319 3 0 0 0 1 0 0 0 0 3 10 9 2 0 0 0 0 0 4 4 3 2 5 6 13 26 E2F_TDP

pfam01448 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 6 3 6 7 10 2 17 13 ELM2

pfam01105 4 0 0 3 3 4 12 12 8 2 12 5 0 4 4 4 9 7 6 5 8 6 12 11 13 19 EMP24_GP25L

smart00615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 7 2 4 6 19 28 EPH_lbd

smart00413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 10 12 9 12 15 45 38 ETS

smart00479 6 0 0 1 2 4 14 12 9 8 14 14 1 7 8 6 6 6 10 14 11 10 14 11 22 23 EXOIII

smart00729 5 0 0 3 2 3 7 7 3 9 9 7 1 3 4 4 3 2 6 9 8 7 4 4 15 7 Elp3

pfam01404 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 7 2 4 6 19 28 Ephrin_lbd

pfam00178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 9 12 9 12 14 45 38 Ets

pfam00754 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 3 22 6 9 23 57 35 F5_F8_type_C

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
smart00231 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 2 22 5 9 19 55 34 FA58C

pfam01557 3 0 0 0 0 0 0 2 1 1 3 4 0 1 11 4 1 1 2 2 4 3 6 5 7 4 FAA_hydrolase

pfam00667 5 0 0 0 2 1 6 5 5 4 3 2 2 5 6 5 3 3 3 4 5 5 6 4 10 13 FAD_binding_1

smart00554 0 0 0 1 0 1 0 0 0 8 24 16 0 2 1 1 0 0 5 5 5 16 48 7 28 21 FAS1

pfam01839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 4 6 4 9 17 FG-GAP

smart00442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 2 2 4 8 29 30 FGF

pfam00167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 1 3 8 28 30 FGF

smart00339 0 0 0 0 0 0 0 0 0 0 0 0 2 4 5 3 4 4 24 9 18 19 23 27 61 50 FH

pfam04500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 4 0 13 7 0 11 5 FLYWCH

smart00063 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 5 9 6 10 12 29 29 FRI

pfam01363 15 0 0 1 0 2 17 25 9 1 12 15 0 6 2 5 5 5 20 14 14 18 20 12 48 37 FYVE

smart00064 15 0 0 1 0 2 21 29 9 1 13 15 0 7 4 6 6 6 21 15 16 20 20 12 51 40 FYVE

pfam01794 4 0 0 0 0 0 3 2 1 5 21 11 0 2 11 10 12 3 2 1 7 4 3 7 14 12 Ferric_reduct

pfam00210 0 0 0 0 0 0 0 0 0 2 5 0 1 0 0 0 0 0 2 2 2 2 5 3 11 7 Ferritin

pfam00147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 3 3 58 19 85 34 36 Fibrinogen_C

pfam00038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 0 3 64 60 Filament

pfam01770 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 4 4 2 3 2 11 8 Folate_carrier

pfam00250 0 0 0 0 0 0 0 0 0 0 0 0 2 4 5 3 4 4 22 9 18 18 23 27 61 50 Fork_head

pfam02434 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 6 6 5 4 4 13 8 6 Fringe

pfam01534 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 4 7 7 5 8 16 16 Frizzled

pfam00757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 3 28 7 9 6 11 12 Furin-like

pfam01392 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 5 14 7 11 13 32 34 Fz

pfam00631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 3 9 4 5 2 19 16 G-gamma

smart00682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 5 2 2 2 7 4 G2F

smart00243 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 5 1 7 1 7 4 14 7 GAS2

pfam02187 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 1 7 1 7 4 14 7 GAS2

pfam03127 0 0 0 0 0 0 0 0 0 0 5 5 0 0 0 0 0 0 3 2 1 0 3 2 9 6 GAT

pfam02841 0 0 0 0 0 0 0 0 0 0 2 4 0 0 0 0 0 0 0 0 1 0 0 0 9 17 GBP_C

pfam02347 1 0 0 0 0 0 2 39 1 1 4 2 0 2 1 1 2 1 1 1 3 2 2 1 4 2 GDC-P

smart00262 34 0 0 0 0 0 0 0 0 5 30 31 1 0 5 2 0 0 12 13 11 29 37 34 67 89 GEL

smart00224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 3 9 4 5 3 22 18 GGL

pfam03359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 2 1 4 2 9 12 GKAP

smart00276 0 0 0 0 0 0 0 0 0 0 6 8 0 0 0 0 0 0 49 26 3 12 13 5 31 24 GLECT

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam02893 9 0 0 0 0 1 1 4 2 1 13 7 0 2 2 2 6 4 9 3 3 6 10 3 24 29 GRAM

smart00568 12 0 0 1 0 1 1 4 3 1 14 10 0 2 4 3 7 5 6 3 2 7 10 5 22 29 GRAM

smart00277 1 0 0 0 0 0 0 0 0 1 3 3 0 0 0 0 0 0 5 3 0 0 0 5 11 14 GRAN

pfam00735 0 0 0 0 0 0 0 0 0 1 0 0 3 7 7 8 7 8 3 3 4 4 9 5 28 18 GTP_CDC

pfam02709 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 3 3 2 2 5 20 12 9 Galactosyl_T_2

pfam00626 19 0 0 2 1 2 1 3 1 2 27 21 0 3 6 2 3 2 10 10 9 16 13 24 53 78 Gelsolin

pfam04488 0 0 0 0 0 2 0 0 0 4 4 0 0 4 7 4 4 4 0 0 0 0 1 2 6 1 Gly_transf_sug

pfam02836 1 0 0 0 0 0 0 0 0 2 2 2 0 0 9 4 0 0 1 1 3 3 3 2 5 3 Glyco_hydro_2_C

pfam03662 0 0 0 0 0 0 0 0 0 0 4 4 0 0 0 0 0 0 0 0 0 0 0 2 7 2 Glyco_hydro_79n

pfam00852 11 0 0 0 0 0 0 2 1 1 3 1 0 0 0 0 0 0 4 5 4 2 8 45 11 6 Glyco_transf_10

pfam03360 0 0 0 0 0 0 0 0 0 0 5 14 0 0 0 0 0 0 7 5 4 3 3 10 5 7 Glyco_transf_43

pfam04666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 1 4 4 3 7 Glyco_transf_54

smart00390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 2 3 2 4 2 14 16 GoLoco

pfam00396 1 0 0 0 0 0 0 0 0 1 3 3 0 0 0 0 0 0 4 2 0 0 0 5 11 14 Granulin

pfam04670 2 0 0 0 2 1 1 4 2 0 0 0 0 2 2 3 2 2 3 2 3 2 2 2 8 7 Gtr1_RagA

smart00428 5 2 0 3 2 2 8 4 3 35 9 14 2 3 2 2 3 2 10 12 6 13 5 6 14 8 H3

smart00471 5 0 0 3 1 8 9 8 2 7 4 5 0 0 5 0 2 1 10 3 19 8 14 7 33 23 HDc

pfam02985 1 0 0 0 0 0 0 0 0 2 11 0 0 1 2 3 0 2 3 3 4 1 1 1 31 20 HEAT

pfam00632 6 0 1 4 3 10 15 15 13 11 7 4 2 7 7 7 5 5 10 9 24 21 21 18 46 40 HECT

smart00119 7 0 2 5 5 12 16 16 17 14 7 4 2 8 8 7 6 5 10 9 26 22 22 19 52 42 HECTc

smart00398 3 0 0 0 3 1 0 3 0 5 13 6 0 4 7 8 7 5 17 13 21 19 34 21 84 80 HMG

pfam00505 2 0 0 0 3 1 0 0 0 4 13 4 0 3 5 7 7 5 15 11 23 19 31 16 69 65 HMG_box

pfam05622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 3 4 2 8 11 HOOK

pfam02793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 7 5 4 9 8 30 30 HRM

pfam02218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 8 3 19 13 HS1_rep

pfam05040 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 6 2 13 9 4 3 HS2ST

pfam00183 6 1 1 4 3 6 5 11 36 7 13 5 1 2 3 2 6 2 5 6 13 4 8 4 11 13 HSP90

smart00120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 5 8 12 13 72 72 HX

pfam02494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 4 10 4 5 1 8 6 HYR

pfam00045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 7 10 9 37 48 Hemopexin

pfam00125 6 3 0 8 6 9 23 7 11 115 31 41 1 7 5 4 6 5 16 46 28 39 9 10 57 47 Histone

smart00008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 7 5 4 8 9 36 30 HormR

pfam03878 1 0 0 0 1 0 1 1 1 1 2 4 1 1 1 1 1 1 1 1 1 1 4 1 7 3 Hrf1

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam06462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 1 5 0 9 11 Hyd_WA

pfam03810 4 0 0 1 1 3 1 0 1 4 10 8 1 7 4 5 7 7 3 4 6 9 17 7 12 10 IBN_N

pfam01485 7 0 0 0 0 0 2 0 1 2 29 6 0 2 1 2 2 1 13 7 8 6 6 5 15 10 IBR

smart00409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 672 395 1086 522 849 262 2055 1110 IG

smart00407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 4 0 0 402 273 IGc1

smart00408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511 294 919 425 685 205 1312 659 IGc2

smart00406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 2 30 28 29 5 455 367 IGv

pfam00478 4 0 0 1 1 2 3 4 3 3 3 4 0 4 2 2 5 2 5 3 4 1 3 3 12 5 IMPDH

smart00187 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 2 7 2 3 6 13 14 INB

pfam01007 0 0 0 0 1 2 0 0 0 3 0 0 0 0 0 0 0 0 3 3 6 7 7 4 19 17 IRK

pfam02174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 4 7 5 3 20 12 IRS

smart00191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 4 2 14 18 28 66 79 Int_alpha

smart00558 5 0 1 1 0 3 2 3 3 4 19 10 0 4 4 4 4 3 14 11 13 10 14 8 35 33 JmjC

pfam02373 6 0 1 2 0 3 2 3 3 6 19 13 0 6 5 5 4 3 14 11 15 12 14 9 39 41 JmjC

pfam02149 3 0 0 0 0 0 0 0 0 1 2 6 0 1 1 1 2 2 5 3 4 2 3 2 11 6 KA1

smart00130 0 0 0 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 4 3 6 2 2 37 90 36 KR

pfam00051 0 0 0 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 3 2 6 2 2 35 89 36 Kringle

pfam02828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 4 0 2 4 2 11 13 L27

smart00569 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 3 4 3 5 2 19 18 L27

pfam01273 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 0 0 0 5 6 0 0 0 2 17 11 LBP_BPI_CETP

pfam03815 0 0 0 6 6 1 0 0 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 22 13 10 LCCL

smart00603 0 0 0 7 6 1 0 0 0 0 0 0 0 0 2 1 1 1 0 0 0 0 0 23 13 10 LCCL

smart00540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 1 0 1 6 4 8 4 LEM

pfam04791 5 0 0 0 1 1 4 2 3 3 5 5 0 1 2 1 0 0 4 4 4 3 4 6 23 11 LMBR1

smart00082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 16 42 25 29 14 91 78 LRRCT

smart00013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 11 16 4 3 8 31 28 LRRNT

pfam01462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 1 3 1 3 9 6 LRRNT

smart00368 2 0 0 0 0 0 5 5 3 3 2 0 0 0 0 0 0 0 2 1 2 1 1 2 12 10 LRR_RI

smart00369 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 1 1 2 0 5 4 8 9 20 16 LRR_TYP

smart00263 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 6 16 0 8 8 LYZ1

pfam00753 9 0 0 4 1 3 8 8 6 4 13 9 3 7 12 7 4 1 12 11 7 10 13 14 23 18 Lactamase_B

smart00282 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 47 41 107 76 85 31 199 159 LamG

smart00560 2 0 0 0 1 0 1 4 0 1 0 0 0 0 0 0 0 0 0 0 2 1 2 1 10 13 LamGL

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
smart00136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 6 5 8 5 8 8 30 19 LamNT

pfam00053 2 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 40 32 49 27 51 42 135 88 Laminin_EGF

pfam00055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 5 8 5 8 8 30 19 Laminin_N

pfam01299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 5 2 9 9 Lamp

pfam00061 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 5 4 4 13 4 2 38 49 Lipocalin

pfam00206 2 0 0 1 0 1 1 2 1 1 5 3 0 5 5 3 3 3 4 2 1 3 10 2 5 4 Lyase_1

pfam00062 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 6 16 0 8 8 Lys

pfam00629 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 2 3 5 3 9 52 42 26 MAM

smart00137 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 8 8 3 3 9 55 42 26 MAM

pfam02991 2 0 0 1 1 1 6 4 26 1 8 2 0 1 1 1 1 1 2 2 0 1 2 4 9 6 MAP1_LC3

pfam01284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 4 2 3 2 4 25 17 MARVEL

smart00391 0 0 0 0 0 0 0 0 0 0 8 5 0 0 0 0 0 0 2 3 2 6 8 3 14 14 MBD

smart00561 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 15 15 9 16 9 59 44 MBT

pfam02820 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 10 14 9 16 9 55 41 MBT

smart00745 4 0 0 0 0 0 2 1 1 0 1 3 0 1 2 1 1 1 4 2 1 2 12 5 8 5 MIT

pfam01853 2 0 0 1 2 2 4 6 4 1 2 0 2 2 3 3 3 3 5 4 6 5 7 4 12 8 MOZ_SAS

smart00242 21 0 0 18 8 23 7 19 4 5 22 13 2 5 6 5 6 8 23 32 90 45 48 22 73 51 MYSc

pfam00994 2 0 0 0 0 0 0 0 0 2 3 2 0 0 3 2 1 1 3 3 1 4 2 5 8 3 MoCF_biosynth

pfam00896 0 0 0 0 0 0 2 2 1 0 0 0 0 2 2 1 2 2 2 3 1 4 8 2 7 3 Mtap_PNP

pfam00063 21 0 0 15 8 21 3 18 4 5 20 14 2 5 5 4 6 6 23 32 83 42 45 22 71 49 Myosin_head

pfam06017 7 0 0 0 0 0 2 5 0 0 1 1 0 1 1 1 2 2 2 2 2 3 5 4 13 12 Myosin_tail_2

pfam01849 2 0 0 1 2 2 3 2 2 2 7 6 0 2 2 2 3 2 3 2 3 3 6 1 11 6 NAC

pfam00956 2 0 0 2 1 3 2 2 3 4 7 8 0 3 2 2 1 1 3 4 2 5 5 3 17 16 NAP

pfam04095 1 0 0 1 0 2 1 1 1 1 2 3 0 1 2 1 1 1 3 1 2 4 3 1 11 5 NAPRTase

smart00562 3 0 0 2 2 3 8 6 3 6 6 2 1 1 1 1 1 1 3 1 7 4 6 10 15 18 NDK

smart00227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 3 4 1 4 3 96 62 NEBU

smart00539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 4 2 3 5 19 12 NIDO

pfam02136 2 0 0 1 2 2 5 4 3 2 15 8 0 3 4 2 2 2 3 3 5 7 5 2 8 7 NTF2

pfam01759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 2 2 4 14 12 NTR

smart00477 1 0 0 0 1 2 4 4 2 1 0 0 0 1 1 1 1 1 2 1 0 7 16 5 7 10 NUC

pfam00939 0 0 0 0 0 0 1 0 2 6 5 0 0 1 2 1 1 2 4 5 8 6 8 13 15 6 Na_sulph_symp

pfam06512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 2 1 2 19 10 Na_trans_assoc

pfam03593 2 0 1 4 1 4 4 3 3 4 4 3 1 1 1 1 0 0 1 1 2 1 2 5 6 9 Nuclear_move

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam03177 4 0 0 0 1 0 2 2 2 1 4 3 2 0 1 1 2 2 2 1 0 2 9 3 2 6 Nucleoporin

pfam01773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 0 3 4 7 5 5 5 5 9 Nucleoside_tra2

smart00284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 1 2 8 26 13 OLF

pfam02191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 1 2 8 24 13 OLF

pfam01237 11 0 0 2 2 2 0 2 0 4 13 2 0 6 5 5 7 6 7 4 6 6 8 6 24 17 Oxysterol_BP

smart00702 8 0 0 1 2 3 4 2 2 20 19 16 1 1 4 5 1 1 9 8 7 4 41 12 25 20 P4Hc

pfam01089 3 0 0 1 1 2 2 2 1 1 2 1 0 1 4 1 1 1 2 2 4 5 5 2 10 5 P5CR

smart00085 0 0 0 0 0 0 0 0 0 0 5 1 0 0 0 0 0 0 2 1 4 6 6 6 13 17 PA2c

pfam01569 5 0 0 0 0 1 3 2 2 0 7 6 1 3 6 4 6 7 9 6 0 6 12 6 20 21 PAP2

pfam04926 1 0 0 0 1 1 4 4 2 1 4 8 1 1 1 1 1 1 3 3 2 1 2 1 6 4 PAP_RNA-bind

pfam03828 2 0 0 0 0 1 3 8 4 0 2 2 0 6 2 3 2 2 14 6 1 3 7 2 18 7 PAP_assoc

pfam04928 1 0 0 1 0 1 4 5 2 1 5 10 1 2 1 1 1 1 3 3 2 2 2 1 7 4 PAP_central

smart00351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 12 40 16 13 4 21 15 PAX

pfam00292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 9 40 13 13 4 21 15 PAX

smart00666 5 0 0 0 0 0 3 2 1 2 35 13 0 2 3 2 2 2 2 2 0 0 2 7 20 14 PB1

pfam00564 2 0 0 0 0 0 0 2 1 1 30 13 0 2 2 2 2 1 2 2 0 0 2 6 17 13 PB1

smart00285 4 0 0 0 0 0 0 0 0 0 12 8 0 2 2 2 4 3 10 7 5 6 9 4 25 15 PBD

smart00018 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 2 1 1 0 21 11 9 PD

smart00141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 2 1 5 1 15 15 PDGF

smart00228 0 0 0 2 0 3 2 10 5 4 7 15 1 0 2 0 2 2 95 75 124 118 141 101 437 321 PDZ

pfam00595 0 0 0 1 0 2 0 1 2 2 0 4 0 0 0 0 1 0 72 58 93 94 114 72 343 277 PDZ

pfam06297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 3 4 2 8 2 4 7 PET

smart00233 63 0 0 3 5 7 19 26 13 4 18 12 2 17 14 13 15 14 61 48 66 67 109 81 372 324 PH

pfam00169 47 0 0 3 3 4 16 20 7 3 13 7 1 14 12 11 11 12 43 34 47 52 76 63 284 242 PH

smart00249 10 0 1 6 7 9 2 3 0 26 69 53 1 22 18 15 16 10 59 34 42 67 79 53 168 131 PHD

pfam00628 7 0 0 5 3 6 0 1 0 22 38 34 1 16 16 12 13 7 36 22 32 50 60 38 121 87 PHD

pfam05682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 4 0 5 2 5 7 11 PHK_AB

smart00142 6 0 0 0 0 0 2 2 0 0 1 1 0 1 1 1 1 1 6 4 4 2 4 3 10 11 PI3K_C2

pfam00792 5 0 0 0 0 0 2 3 0 0 1 1 0 1 1 1 1 1 6 4 4 2 4 4 11 11 PI3K_C2

smart00144 4 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 2 2 2 1 2 2 9 8 PI3K_rbd

pfam00640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21 14 14 16 15 12 65 48 PID

smart00088 12 0 0 6 7 7 8 12 8 8 13 14 4 11 10 11 7 8 13 11 14 12 15 10 21 16 PINT

smart00670 2 0 0 1 0 0 1 2 0 2 1 2 1 3 2 2 6 4 3 3 4 3 5 4 10 5 PINc

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam01735 0 0 0 0 0 0 0 0 0 0 0 0 0 5 3 2 6 5 0 0 0 0 0 5 8 6 PLA2_B

smart00250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 1 0 0 4 31 223 182 PLEC

smart00352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 4 8 4 7 2 18 28 POU

smart00462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32 18 22 21 25 15 90 56 PTB

smart00310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 8 7 5 3 20 12 PTBI

smart00159 1 0 0 0 1 0 0 2 0 1 0 2 0 0 0 0 0 0 1 1 3 4 4 4 18 20 PTX

pfam00855 2 0 0 0 0 1 2 3 1 1 12 8 0 3 1 0 2 2 2 1 2 2 12 11 52 29 PWWP

smart00293 3 0 0 0 0 1 2 3 2 3 12 8 0 3 1 1 2 2 2 1 2 3 12 12 52 31 PWWP

pfam00787 6 0 0 0 1 1 3 6 3 3 9 5 1 11 7 11 12 13 13 10 20 15 18 23 60 54 PX

smart00312 6 0 0 0 2 1 3 7 3 3 8 6 1 11 8 10 14 14 14 10 18 15 17 22 58 53 PX

pfam01483 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1 1 7 7 22 4 5 5 11 8 P_proprotein

pfam01562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 5 4 9 5 48 57 Pep_M12B_propep

pfam03416 4 0 0 0 1 2 3 3 2 2 2 3 0 1 1 1 1 1 3 4 3 3 3 2 13 8 Peptidase_C54

pfam00413 0 0 0 0 0 0 0 0 0 0 5 1 0 0 0 0 0 0 4 4 2 3 4 7 33 31 Peptidase_M10

pfam03933 0 0 0 0 0 0 0 0 0 1 5 1 0 0 0 0 0 0 2 2 2 3 4 6 21 28 Peptidase_M10_N

pfam03036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 4 4 2 8 13 Perilipin

pfam00068 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 1 0 1 1 6 13 15 Phospholip_A2_1

pfam00157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 4 8 4 7 2 18 28 Pou

pfam00432 9 0 0 5 5 0 14 7 6 5 39 8 2 10 7 7 8 9 10 8 9 9 9 10 18 18 Prenyltrans

pfam05044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 3 2 4 2 10 4 Prox1

smart00393 3 0 0 0 0 1 5 3 2 0 6 4 0 2 4 4 4 2 2 3 0 2 6 6 11 16 R3H

pfam01424 1 0 0 0 0 0 1 2 1 0 2 1 0 3 1 3 3 2 2 3 0 2 6 4 11 15 R3H

pfam00788 3 0 0 0 0 0 0 0 0 0 0 0 0 2 2 2 1 1 24 14 23 18 22 7 52 41 RA

pfam00415 10 0 0 0 2 1 0 2 1 0 11 7 1 0 0 0 0 0 3 3 11 4 3 9 26 23 RCC1

pfam02257 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1 2 1 2 0 3 3 4 11 12 RFX_DNA_binding

smart00315 11 0 0 0 0 0 0 0 0 0 1 0 0 2 4 5 5 3 25 18 12 14 21 29 63 48 RGS

pfam00554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 3 5 3 13 18 RHD

smart00450 8 0 0 0 0 2 16 17 15 19 19 13 2 8 10 10 10 10 18 15 2 8 11 15 33 26 RHOD

smart00394 0 0 0 0 0 1 1 1 1 1 0 0 0 1 0 0 1 0 2 2 2 3 2 4 15 14 RIIa

smart00582 4 0 0 1 4 1 2 1 0 3 10 4 1 4 3 3 3 3 7 5 7 9 8 8 17 14 RPR

smart00361 8 0 0 4 4 6 6 2 2 5 23 12 3 4 7 8 3 7 13 14 12 7 20 13 40 38 RRM_1

smart00593 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 6 4 8 11 6 25 17 RUN

pfam02759 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 5 4 6 10 6 28 21 RUN

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam00077 0 0 0 0 1 1 0 0 0 1 1 35 0 0 0 0 0 1 3 2 1 4 7 1 19 7 RVP

pfam04712 0 0 0 2 0 1 4 4 4 4 0 0 0 0 0 0 0 0 0 0 0 1 2 3 4 8 Radial_spoke

smart00160 2 0 0 2 1 1 1 1 1 1 6 3 1 3 3 3 3 3 5 3 4 6 13 7 22 12 RanBD

pfam00638 2 0 0 2 1 1 1 1 1 1 6 3 1 3 3 2 3 3 5 2 2 3 9 7 18 9 Ran_BP1

pfam00616 11 0 0 0 0 0 0 0 0 0 0 0 1 2 3 4 3 3 3 3 5 5 7 6 23 18 RasGAP

smart00323 12 0 0 0 0 1 0 0 0 0 0 0 0 2 3 4 4 3 4 3 6 5 10 7 33 31 RasGAP

smart00324 45 0 0 1 1 1 1 1 1 0 9 5 3 10 9 10 12 11 32 24 33 23 36 28 120 91 RhoGAP

pfam00620 44 0 0 1 1 1 1 1 1 0 9 5 3 10 7 8 11 9 31 23 33 22 35 28 112 89 RhoGAP

smart00325 48 0 1 0 0 0 0 0 0 0 0 0 1 8 5 5 5 4 34 21 39 27 53 30 117 92 RhoGEF

pfam00621 47 0 1 0 0 0 0 0 0 0 0 0 1 7 6 5 4 2 30 21 37 25 46 28 112 89 RhoGEF

pfam00581 4 0 0 0 0 2 9 12 7 14 15 8 2 8 7 6 10 7 10 9 1 7 8 9 30 24 Rhodanese

smart00454 9 0 0 1 1 0 4 4 0 5 7 5 0 4 5 5 1 1 36 25 20 31 40 29 136 125 SAM

pfam00536 4 0 0 0 1 0 4 0 0 1 5 2 0 4 4 3 1 1 24 19 12 19 28 19 91 91 SAM

smart00251 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 10 5 10 10 22 20 SAM_PNT

pfam02198 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 9 4 9 10 19 16 SAM_PNT

smart00258 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 4 3 2 1 1 3 9 14 SAND

pfam01342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 3 2 1 1 3 9 14 SAND

smart00178 41 0 1 9 7 10 24 29 18 16 39 30 7 8 9 10 15 11 38 35 40 31 36 48 72 82 SAR

pfam01758 0 0 0 0 0 0 0 0 0 1 5 3 0 0 1 1 1 0 0 0 0 0 1 8 3 4 SBF

pfam00497 0 0 0 0 0 0 0 0 0 0 14 7 0 0 0 0 0 0 10 9 40 18 19 8 24 22 SBP_bac_3

smart00200 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 5 0 0 0 1 30 18 SEA

pfam01390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 4 0 0 0 1 21 17 SEA

smart00553 1 0 0 1 0 1 2 0 0 0 4 2 0 1 1 1 1 1 2 1 1 1 3 2 10 7 SEP

smart00317 21 0 0 6 6 16 41 40 24 29 40 22 1 10 15 18 7 6 37 26 29 41 41 18 74 59 SET

pfam00017 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 50 32 49 34 46 48 149 149 SH2

smart00252 11 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 1 1 73 47 53 38 48 51 159 160 SH2

smart00326 31 0 0 0 0 0 6 10 6 0 3 3 0 21 25 24 28 26 105 88 131 86 179 103 360 332 SH3

pfam00018 25 0 0 0 0 0 5 10 5 0 2 3 0 21 18 21 27 22 73 74 110 74 148 87 309 285 SH3

pfam02483 5 0 1 6 4 3 5 6 3 7 6 4 5 5 6 6 5 5 7 19 11 9 11 6 13 9 SMC_C

pfam02463 7 1 1 6 5 5 6 7 4 8 10 6 7 6 6 7 6 6 8 18 8 11 11 5 12 10 SMC_N

pfam06470 4 1 0 5 4 4 5 6 4 3 6 3 5 4 4 4 4 4 5 17 8 6 8 4 8 7 SMC_hinge

pfam00209 0 0 0 1 0 8 0 0 0 0 0 0 0 0 1 0 0 0 21 27 94 22 41 63 42 32 SNF

smart00253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 4 4 15 6 29 31 SOCS

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
pfam00622 8 0 0 1 0 3 13 17 8 8 7 1 0 3 2 3 3 3 15 32 35 17 25 16 117 80 SPRY

smart00449 8 1 0 1 0 4 19 23 8 8 7 1 0 3 3 3 4 3 15 33 36 18 25 17 120 84 SPRY

smart00202 0 0 0 2 2 0 0 0 0 49 0 0 0 0 0 0 0 0 4 4 8 8 16 9 155 109 SR

pfam00530 0 0 0 2 2 0 0 0 0 23 0 0 0 0 0 0 0 0 2 2 6 8 12 8 143 100 SRCR

pfam03365 1 0 0 0 0 0 1 2 1 1 1 4 1 2 1 1 2 2 1 1 0 3 4 3 15 6 STAG

pfam01740 2 1 0 0 0 1 0 0 1 2 12 8 0 4 2 2 1 2 7 5 2 3 4 4 20 9 STAS

pfam02201 1 0 0 1 1 2 0 0 0 1 21 8 1 2 2 2 2 2 3 3 2 2 3 1 14 11 SWIB

pfam00995 9 0 1 9 6 5 7 46 8 6 7 11 4 4 6 4 5 7 8 9 6 6 6 5 9 11 Sec1

pfam01369 6 0 0 0 1 5 5 4 4 2 7 6 1 6 4 4 5 4 6 5 12 5 10 6 23 18 Sec7

pfam01403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 5 15 7 14 11 45 40 Sema

smart00630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 7 16 7 15 12 51 44 Sema

pfam00916 5 1 0 1 2 1 2 2 1 3 12 9 1 4 3 4 4 3 10 12 15 14 13 11 28 13 Sulfate_transp

pfam02750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 3 4 4 0 4 6 Synapsin_C

smart00164 33 0 0 11 8 15 20 29 13 11 25 13 3 13 12 11 10 9 26 22 39 25 38 30 85 57 TBC

pfam00566 30 0 0 5 8 10 7 20 4 9 23 10 3 11 12 10 8 7 21 15 28 20 34 23 66 45 TBC

smart00706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 4 0 5 4 TECPR

smart00510 1 0 0 2 1 1 1 2 1 2 6 4 1 1 2 1 1 2 1 1 3 3 3 2 10 8 TFS2M

smart00509 2 0 0 0 1 1 0 0 1 1 15 5 0 0 2 1 0 0 2 3 0 2 1 2 9 7 TFS2N

pfam03299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 1 2 1 2 1 10 7 TF_AP-2

smart00204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 5 16 7 9 11 37 41 TGFB

pfam00019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 5 16 7 9 11 40 44 TGF_beta

pfam00688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 4 5 7 8 21 24 TGFb_propeptide

smart00460 4 0 0 0 0 0 0 0 0 1 2 0 0 3 2 3 2 2 2 2 4 4 6 6 15 16 TGc

pfam05485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 3 0 11 35 12 11 7 THAP

smart00255 1 0 0 0 0 0 0 0 0 4 143 1 0 0 0 0 0 0 6 3 25 15 17 10 28 27 TIR

smart00584 6 0 0 3 3 3 3 3 4 4 4 3 1 2 1 3 2 2 7 6 10 7 16 3 10 11 TLDc

pfam03920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 1 2 2 6 8 TLE_N

pfam04201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 7 0 13 7 TPD52

pfam05731 2 0 0 0 0 0 2 1 2 8 0 0 0 0 0 0 0 0 1 1 0 1 1 4 3 5 TROVE

smart00210 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 7 2 11 10 4 9 43 43 TSPN

pfam05735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 1 1 4 5 7 TSP_C

pfam02210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 2 8 3 2 9 30 36 TSP_N

pfam00567 2 0 0 0 0 2 1 1 1 1 2 2 0 1 1 1 0 0 11 10 7 29 63 15 38 33 TUDOR

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
smart00211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 11 12 12 10 11 30 35 TY

pfam00086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 4 11 7 4 10 29 33 Thyroglobulin_1

pfam06309 2 0 0 2 0 3 4 6 4 1 5 8 0 1 2 1 1 2 3 2 0 3 1 2 14 8 Torsin

pfam00405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 12 7 5 6 13 Transferrin

pfam00927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 3 4 1 23 30 Transglut_C

pfam01841 4 0 0 0 0 0 0 0 0 0 1 0 0 1 1 1 1 1 1 1 1 3 5 4 15 16 Transglut_core

pfam04906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 4 1 3 6 0 16 11 Tweety

pfam00264 3 0 0 0 0 0 0 0 0 0 0 5 0 0 13 7 0 0 6 6 0 0 0 14 6 4 Tyrosinase

pfam00627 3 0 0 0 0 4 2 2 1 2 11 7 0 3 3 1 4 3 1 2 2 6 11 6 21 13 UBA

pfam02134 5 0 0 2 3 2 3 6 4 3 5 3 2 3 3 3 2 4 3 3 10 6 8 4 9 18 UBACT

pfam00443 37 0 0 12 9 21 31 38 20 20 58 25 5 25 20 22 31 29 47 34 42 37 50 45 122 103 UCH

pfam01170 1 0 0 1 1 1 1 2 1 0 2 3 0 2 2 3 2 2 4 5 4 1 2 3 9 6 UPF0020

pfam03006 3 0 0 0 0 1 2 4 3 2 8 6 1 2 2 2 5 5 6 6 3 5 5 6 13 11 UPF0073

pfam01209 17 0 0 1 1 6 5 6 3 9 15 14 1 6 17 27 2 3 9 10 10 4 5 30 10 13 Ubie_methyltran

pfam04615 1 0 0 0 1 1 1 3 1 1 4 2 1 3 2 2 3 3 2 2 0 3 3 2 5 9 Utp14

pfam00790 1 0 0 0 0 0 1 2 1 2 8 7 0 5 4 4 4 3 6 5 4 5 5 4 17 16 VHS

smart00288 1 0 0 0 0 0 1 2 2 2 10 8 0 5 4 4 5 3 6 5 4 5 5 4 17 16 VHS

smart00167 8 0 0 0 1 1 1 3 1 0 2 3 1 2 2 3 2 2 4 4 2 2 3 3 13 16 VPS9

smart00214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 7 6 15 5 33 37 VWC

pfam00093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 11 11 6 34 34 VWC

smart00215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 0 3 9 17 15 VWC_out

pfam01505 12 0 0 0 0 0 4 6 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 6 10 Vault

pfam01044 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 12 10 7 9 6 16 12 Vinculin

smart00217 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 2 5 2 4 0 8 7 WAP

pfam00400 186 4 5 41 30 56 113 104 70 135 227 192 26 130 165 118 87 89 154 138 214 220 240 199 430 395 WD40

smart00320 368 6 8 82 68 109 246 247 141 246 465 364 57 233 259 221 161 162 293 264 424 398 460 398 813 702 WD40

smart00321 2 0 0 0 0 0 0 0 0 9 0 0 0 1 3 21 4 2 1 0 0 2 3 3 10 6 WSC

pfam01822 2 0 0 0 0 0 0 0 0 2 0 0 0 1 3 16 4 2 1 0 0 1 3 1 7 5 WSC

smart00456 5 0 0 4 1 5 13 17 7 9 11 7 1 10 7 8 8 7 38 27 50 41 43 31 119 83 WW

pfam00397 4 0 0 4 1 2 10 8 5 6 6 3 0 9 3 5 6 6 21 17 38 36 31 20 97 66 WW

smart00678 7 0 0 0 2 0 2 2 1 0 1 0 0 0 0 0 0 0 5 2 1 2 5 2 17 14 WWE

pfam02825 0 0 0 0 2 0 0 0 0 0 2 1 0 0 0 0 0 0 5 2 1 2 7 2 16 11 WWE

pfam04893 3 0 0 0 0 2 5 5 3 1 4 3 1 3 4 3 2 2 7 6 3 2 3 5 10 11 Yip1

Species Dd Gt Cm Pf Ch Tg Tb Tc Lm Cr At Os Ec Sp An Nc Sc Cg Ce Cb Am Ag Dm Ci Hs Mm
smart00355 0 0 0 0 0 0 0 0 0 0 3 0 0 3 7 2 1 4 2 2 2 6 5 4 30 30 ZnF_C2H2

smart00451 6 0 0 2 2 3 0 0 2 1 15 2 0 4 5 4 5 5 6 3 6 13 16 8 41 28 ZnF_U1

smart00290 5 0 0 3 2 2 5 4 3 1 8 5 1 7 0 1 4 4 5 6 8 7 7 5 14 16 ZnF_UBP

smart00291 5 0 0 2 0 2 4 3 3 1 11 10 0 3 9 3 2 2 12 8 17 13 19 12 33 21 ZnF_ZZ

smart00014 5 0 0 0 0 1 4 2 2 0 5 6 1 4 5 3 6 7 7 6 0 6 9 5 23 22 acidPPc

pfam02492 3 0 0 1 1 2 1 2 2 17 3 3 0 1 4 2 1 1 0 0 3 0 0 0 11 2 cobW

pfam03455 2 0 0 0 0 0 0 0 0 0 1 0 0 1 1 1 0 0 6 5 7 9 10 3 35 25 dDENN

pfam00047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79 34 231 111 110 35 496 319 ig

pfam03456 5 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 0 0 6 5 6 8 9 4 33 28 uDENN

pfam00110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 5 19 13 14 11 24 29 wnt

pfam00096 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 1 5 0 1 1 1 2 0 16 6 zf-C2H2

pfam01530 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 15 5 4 6 39 42 zf-C2HC

pfam02008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 3 1 4 3 7 13 zf-CXXC

pfam02891 3 0 0 1 1 1 6 6 5 0 3 4 0 0 2 1 2 2 6 1 2 3 11 2 6 6 zf-MIZ

pfam00641 0 0 0 0 0 0 0 2 1 0 2 0 0 1 2 1 2 2 0 1 0 0 4 0 17 10 zf-RanBP

pfam02148 5 0 0 2 1 1 5 4 3 1 7 5 1 4 1 0 3 3 5 6 7 6 6 5 13 15 zf-UBP

Species	Dd	Gt	Cm	Pf	Ch	Tg	Tb	Tc	Lm	Cr	At	Os	Ec	Sp	An	Nc	Sc	Cg	Ce	Cb	Am	Ag	Dm	Ci	Hs	Mm
pfam05902	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	4	1	0	2	2	0	7	10	4_1_CTD
pfam00001	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	177	131	210	103	133	142	934	1684	7tm_1
pfam01661	3	0	0	2	0	2	2	3	0	3	4	2	0	0	2	1	0	0	1	1	2	3	1	25	15	12	A1pp
smart00506	3	0	0	2	0	3	2	2	1	3	4	2	0	0	3	1	2	2	1	1	2	5	6	31	15	14	A1pp
smart00608	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	2	5	6	5	3	36	48	ACR
smart00552	2	0	0	0	0	1	1	2	1	0	1	2	0	1	1	1	1	1	5	1	4	3	4	4	13	11	ADEAMc
pfam05110	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	2	2	2	23	32	AF-4
smart00248	79	0	0	8	12	15	23	44	20	44	75	76	1	9	76	22	7	14	126	90	295	151	190	146	637	521	ANK
smart00335	5	0	0	0	0	0	0	0	0	0	27	16	0	0	8	5	0	0	18	10	18	36	22	15	92	84	ANX
smart00177	91	1	1	17	10	22	49	48	29	26	87	54	12	18	21	20	26	20	67	55	65	61	76	74	156	156	ARF
pfam01388	2	0	0	0	1	1	0	0	0	2	6	3	0	3	2	3	2	1	4	4	8	6	8	6	25	19	ARID
smart00185	11	3	0	5	6	7	12	12	7	10	57	33	1	15	6	10	12	12	14	18	25	23	37	25	102	89	ARM
smart00570	1	0	0	0	0	0	0	0	0	0	3	2	0	1	2	2	1	1	4	2	4	2	5	3	10	5	AWS
pfam02137	2	0	0	0	0	1	1	2	0	0	1	1	0	1	1	1	1	0	5	1	4	3	4	4	13	11	A_deamin
pfam00928	7	0	0	4	3	7	8	7	4	3	8	5	1	3	4	4	6	5	6	7	7	5	5	7	21	16	Adap_comp_sub
pfam02883	2	0	0	1	0	1	2	1	0	1	4	3	0	4	2	3	3	2	2	1	4	4	8	3	14	14	Alpha_adaptinC2
pfam00266	6	0	0	1	2	6	2	7	7	7	6	4	1	5	4	5	5	4	5	8	6	7	5	13	9	7	Aminotran_5
pfam00023	96	0	0	11	16	11	24	38	16	40	66	62	0	10	77	18	8	11	147	105	313	160	188	153	642	539	Ank
pfam00191	6	0	0	0	0	0	0	0	0	0	27	14	0	0	7	5	0	0	18	10	14	36	22	16	91	88	Annexin
pfam00025	26	0	1	8	6	7	23	27	14	14	24	19	4	5	7	7	7	6	15	15	16	14	18	28	36	44	Arf
smart00105	12	0	0	2	3	3	6	12	7	4	17	16	2	6	5	4	6	5	9	8	8	12	16	14	41	28	ArfGap
pfam01412	12	0	0	2	3	3	6	12	7	4	17	16	2	6	5	4	6	5	9	8	8	12	16	14	41	28	ArfGap
pfam01603	1	0	0	0	0	1	0	0	0	1	8	7	1	2	1	1	1	1	3	2	5	2	6	3	8	16	B56
smart00721	2	0	0	0	0	0	0	0	0	0	5	0	0	4	4	4	3	3	9	5	7	6	5	4	25	25	BAR
pfam03114	1	0	0	0	0	0	0	0	0	0	0	0	0	2	4	3	3	2	1	1	2	2	1	1	8	6	BAR
smart00502	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	3	0	2	5	3	13	10	BBC
smart00336	19	0	0	1	2	2	2	0	0	0	29	8	1	0	0	0	0	1	9	5	3	5	6	6	57	45	BBOX
smart00337	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	1	2	3	4	18	16	BCL
pfam00653	0	0	0	0	0	0	0	0	0	0	0	0	1	2	2	1	2	0	3	3	17	10	8	33	21	47	BIR
smart00238	0	0	0	0	0	0	0	0	0	0	0	0	1	2	2	1	1	0	3	3	17	10	8	33	21	48	BIR
pfam00533	14	0	0	1	3	3	4	7	2	5	15	14	1	8	9	11	4	6	21	5	8	16	24	12	32	43	BRCT
smart00501	2	0	0	0	1	1	0	0	0	3	7	4	0	4	2	4	2	1	4	4	8	6	8	6	25	19	BRIGHT
smart00592	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	2	0	3	4	1	13	8	BRK
Species	Dd	Gt	Cm	Pf	Ch	Tg	Tb	Tc	Lm	Cr	At	Os	Ec	Sp	An	Nc	Sc	Cg	Ce	Cb	Am	Ag	Dm	Ci	Hs	Mm
smart00297	15	0	3	6	9	12	7	9	5	10	29	19	5	14	8	10	16	12	30	42	41	26	56	27	123	62	BROMO
smart00576	2	0	0	0	0	1	0	0	0	0	3	1	2	2	1	3	1	2	3	2	2	1	5	2	9	9	BTP
pfam00373	6	0	0	0	0	0	0	3	0	1	1	1	0	0	0	0	0	0	18	12	27	22	23	17	57	58	Band_41
pfam02138	8	0	0	1	1	2	6	5	4	3	6	6	0	1	1	1	1	1	4	3	5	6	5	6	19	8	Beach
pfam00439	14	0	3	6	9	12	5	6	5	8	27	17	5	12	7	7	15	13	30	40	40	25	50	25	114	56	Bromodomain
smart00239	38	0	0	3	6	15	16	22	16	21	150	92	2	15	15	17	17	13	76	65	111	59	78	76	277	230	C2
pfam00168	33	0	0	1	1	9	12	13	10	18	142	84	1	14	12	16	12	11	64	54	97	54	71	66	261	223	C2
smart00643	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	1	2	3	4	16	15	C345C
smart00266	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	3	3	6	0	7	6	CAD
pfam04218	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	2	6	0	9	6	CENP-B_N
smart00033	40	0	0	1	0	0	2	4	2	3	29	15	3	9	7	8	7	7	51	40	70	37	76	31	142	127	CH
pfam05679	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	6	4	8	4	6	12	21	18	CHGN
smart00298	9	0	0	2	3	3	0	0	1	9	15	15	2	10	17	11	4	3	22	11	16	11	24	10	44	39	CHROMO
pfam00878	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	8	12	24	13	CIMR
pfam02487	1	0	0	0	0	0	2	2	2	0	0	0	0	1	1	2	1	1	4	4	4	2	4	0	16	8	CLN3
pfam00780	3	0	0	0	0	0	0	0	0	0	1	2	1	3	2	3	3	2	9	7	10	5	10	6	25	20	CNH
smart00036	2	0	0	0	0	0	0	2	0	1	1	2	1	4	2	3	3	2	9	6	10	5	10	7	27	21	CNH
pfam04516	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	2	0	0	1	0	3	5	5	3	18	10	CP2
pfam00313	0	0	0	1	1	2	7	3	2	2	4	2	0	0	0	0	0	0	6	5	6	7	13	4	25	22	CSD
smart00357	0	0	0	1	1	2	5	5	4	1	4	2	0	0	0	0	0	0	6	5	6	8	13	5	28	22	CSP
smart00041	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	1	8	3	4	9	24	23	CT
smart00546	1	0	0	0	0	0	0	0	1	0	1	1	0	2	0	1	7	4	2	2	1	3	3	4	14	7	CUE
pfam02845	0	0	0	0	0	0	0	0	0	0	1	1	0	2	0	1	5	3	2	2	1	2	1	3	10	7	CUE
pfam02376	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	7	6	7	4	5	2	16	20	CUT
smart00043	3	0	0	0	0	0	0	0	0	1	8	8	0	0	0	0	0	0	3	4	1	0	4	0	28	44	CY
pfam01049	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	10	13	3	2	26	26	Cadherin_C
pfam01067	6	0	0	0	0	0	3	2	1	1	1	0	0	0	0	1	0	0	7	6	1	6	6	4	16	15	Calpain_III
pfam00385	3	0	0	1	1	1	0	0	0	7	3	2	1	4	2	4	1	1	8	4	6	5	10	4	18	19	Chromo
pfam01217	6	0	0	4	1	4	6	7	4	4	8	8	1	5	3	3	5	4	4	4	1	5	8	4	14	11	Clat_adaptor_s
pfam04594	4	0	0	2	0	2	1	4	2	2	2	1	1	1	2	3	2	2	3	2	0	3	4	6	9	4	Cnd1
pfam03712	0	0	0	0	0	0	0	0	0	2	0	0	0	0	0	0	0	0	4	3	6	5	5	12	4	7	Cu2_monoox_C
pfam00031	2	0	0	0	0	0	0	0	0	0	7	7	0	0	0	0	0	0	2	3	1	0	2	0	24	41	Cystatin
smart00021	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	6	4	2	2	5	4	9	7	DAX
Species	Dd	Gt	Cm	Pf	Ch	Tg	Tb	Tc	Lm	Cr	At	Os	Ec	Sp	An	Nc	Sc	Cg	Ce	Cb	Am	Ag	Dm	Ci	Hs	Mm
smart00537	2	0	0	1	1	1	2	3	0	0	0	0	0	0	0	0	0	0	9	6	3	4	9	10	18	28	DCX
pfam03607	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	6	6	2	2	6	8	15	27	DCX
pfam02862	4	0	0	1	1	2	0	0	0	0	2	0	0	2	2	3	1	2	5	5	7	3	7	4	11	13	DDHD
smart00005	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	9	6	12	4	7	6	36	30	DEATH
pfam02141	7	0	0	0	0	0	1	4	1	2	5	5	0	1	2	2	0	0	6	5	6	9	11	5	38	31	DENN
smart00049	7	0	0	0	0	1	0	0	0	1	1	3	0	6	5	5	5	3	13	9	10	6	8	10	45	28	DEP
pfam00610	5	0	0	0	0	1	0	0	0	0	1	3	0	5	3	3	5	3	12	9	9	6	7	6	42	28	DEP
smart00050	0	0	0	0	0	0	0	0	0	0	0	0	1	1	1	0	0	0	4	4	6	7	9	3	31	42	DISIN
pfam00778	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	6	4	2	2	5	4	9	7	DIX
smart00684	2	0	0	0	0	0	0	0	0	2	0	3	0	0	0	0	0	0	2	2	1	2	4	2	9	4	DM15
smart00195	28	0	0	3	3	10	28	37	19	16	19	14	1	5	9	9	9	8	58	43	28	23	41	28	110	89	DSPc
pfam00782	16	0	0	3	2	7	24	25	14	13	15	13	0	4	7	8	6	5	19	17	14	13	21	14	54	51	DSPc
pfam06327	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	5	1	9	5	DUF1053
pfam04802	1	0	0	0	1	1	4	0	1	1	2	2	0	1	1	1	1	2	2	1	1	1	2	1	9	5	DUF625
pfam05885	1	0	0	0	0	0	0	0	0	1	1	1	0	0	0	0	0	0	3	4	5	4	4	6	13	12	DUF857
smart00695	5	0	0	1	0	1	1	0	1	0	6	2	0	2	1	1	1	1	3	2	4	3	6	3	13	12	DUSP
smart00572	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	1	6	3	3	5	11	7	DZF
pfam00531	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	9	5	11	4	7	3	34	38	Death
pfam06920	7	0	0	0	0	0	0	0	0	0	1	1	0	0	1	1	0	0	2	5	7	3	6	3	20	12	Ded_cyto
pfam00200	0	0	0	0	0	0	0	0	0	0	0	0	1	1	1	0	0	0	5	4	5	7	9	3	31	41	Disintegrin
pfam02319	3	0	0	0	1	0	0	0	0	3	10	9	2	0	0	0	0	0	4	4	3	2	5	6	13	26	E2F_TDP
pfam01448	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0	0	6	3	6	7	10	2	17	13	ELM2
pfam01105	4	0	0	3	3	4	12	12	8	2	12	5	0	4	4	4	9	7	6	5	8	6	12	11	13	19	EMP24_GP25L
smart00615	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	7	2	4	6	19	28	EPH_lbd
smart00413	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	13	10	12	9	12	15	45	38	ETS
smart00479	6	0	0	1	2	4	14	12	9	8	14	14	1	7	8	6	6	6	10	14	11	10	14	11	22	23	EXOIII
pfam01404	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	7	2	4	6	19	28	Ephrin_lbd
pfam00178	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	12	9	12	9	12	14	45	38	Ets
pfam00754	7	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	4	3	22	6	9	23	57	35	F5_F8_type_C
smart00231	8	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	3	2	22	5	9	19	55	34	FA58C
pfam00667	5	0	0	0	2	1	6	5	5	4	3	2	2	5	6	5	3	3	3	4	5	5	6	4	10	13	FAD_binding_1
pfam01839	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	0	4	6	4	9	17	FG-GAP
smart00442	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	2	2	2	4	8	29	30	FGF
Species	Dd	Gt	Cm	Pf	Ch	Tg	Tb	Tc	Lm	Cr	At	Os	Ec	Sp	An	Nc	Sc	Cg	Ce	Cb	Am	Ag	Dm	Ci	Hs	Mm
pfam00167	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	2	2	1	3	8	28	30	FGF
smart00339	0	0	0	0	0	0	0	0	0	0	0	0	2	4	5	3	4	4	24	9	18	19	23	27	61	50	FH
smart00063	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	8	5	9	6	10	12	29	29	FRI
pfam01363	15	0	0	1	0	2	17	25	9	1	12	15	0	6	2	5	5	5	20	14	14	18	20	12	48	37	FYVE
smart00064	15	0	0	1	0	2	21	29	9	1	13	15	0	7	4	6	6	6	21	15	16	20	20	12	51	40	FYVE
pfam00210	0	0	0	0	0	0	0	0	0	2	5	0	1	0	0	0	0	0	2	2	2	2	5	3	11	7	Ferritin
pfam00038	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	7	7	0	0	0	3	64	60	Filament
pfam01770	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	3	4	4	2	3	2	11	8	Folate_carrier
pfam00250	0	0	0	0	0	0	0	0	0	0	0	0	2	4	5	3	4	4	22	9	18	18	23	27	61	50	Fork_head
pfam02434	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	1	0	0	6	6	5	4	4	13	8	6	Fringe
pfam01534	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	4	7	7	5	8	16	16	Frizzled
pfam01392	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	8	5	14	7	11	13	32	34	Fz
pfam00631	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	3	9	4	5	2	19	16	G-gamma
smart00243	1	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	5	1	7	1	7	4	14	7	GAS2
pfam02187	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	1	7	1	7	4	14	7	GAS2
pfam03127	0	0	0	0	0	0	0	0	0	0	5	5	0	0	0	0	0	0	3	2	1	0	3	2	9	6	GAT
pfam02841	0	0	0	0	0	0	0	0	0	0	2	4	0	0	0	0	0	0	0	0	1	0	0	0	9	17	GBP_C
smart00262	34	0	0	0	0	0	0	0	0	5	30	31	1	0	5	2	0	0	12	13	11	29	37	34	67	89	GEL
smart00224	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	3	9	4	5	3	22	18	GGL
pfam03359	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	2	1	4	2	9	12	GKAP
pfam02893	9	0	0	0	0	1	1	4	2	1	13	7	0	2	2	2	6	4	9	3	3	6	10	3	24	29	GRAM
smart00568	12	0	0	1	0	1	1	4	3	1	14	10	0	2	4	3	7	5	6	3	2	7	10	5	22	29	GRAM
smart00277	1	0	0	0	0	0	0	0	0	1	3	3	0	0	0	0	0	0	5	3	0	0	0	5	11	14	GRAN
pfam00735	0	0	0	0	0	0	0	0	0	1	0	0	3	7	7	8	7	8	3	3	4	4	9	5	28	18	GTP_CDC
pfam02709	0	0	0	0	0	2	0	0	0	0	0	0	0	0	0	0	0	0	3	3	2	2	5	20	12	9	Galactosyl_T_2
pfam00626	19	0	0	2	1	2	1	3	1	2	27	21	0	3	6	2	3	2	10	10	9	16	13	24	53	78	Gelsolin
pfam00852	11	0	0	0	0	0	0	2	1	1	3	1	0	0	0	0	0	0	4	5	4	2	8	45	11	6	Glyco_transf_10
pfam04666	0	0	0	0	0	0	0	0	0	0	0	0	0	0	3	0	0	0	0	0	0	1	4	4	3	7	Glyco_transf_54
smart00390	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	7	2	3	2	4	2	14	16	GoLoco
pfam00396	1	0	0	0	0	0	0	0	0	1	3	3	0	0	0	0	0	0	4	2	0	0	0	5	11	14	Granulin
pfam04670	2	0	0	0	2	1	1	4	2	0	0	0	0	2	2	3	2	2	3	2	3	2	2	2	8	7	Gtr1_RagA
smart00471	5	0	0	3	1	8	9	8	2	7	4	5	0	0	5	0	2	1	10	3	19	8	14	7	33	23	HDc
pfam02985	1	0	0	0	0	0	0	0	0	2	11	0	0	1	2	3	0	2	3	3	4	1	1	1	31	20	HEAT
Species	Dd	Gt	Cm	Pf	Ch	Tg	Tb	Tc	Lm	Cr	At	Os	Ec	Sp	An	Nc	Sc	Cg	Ce	Cb	Am	Ag	Dm	Ci	Hs	Mm
pfam00632	6	0	1	4	3	10	15	15	13	11	7	4	2	7	7	7	5	5	10	9	24	21	21	18	46	40	HECT
smart00119	7	0	2	5	5	12	16	16	17	14	7	4	2	8	8	7	6	5	10	9	26	22	22	19	52	42	HECTc
smart00398	3	0	0	0	3	1	0	3	0	5	13	6	0	4	7	8	7	5	17	13	21	19	34	21	84	80	HMG
pfam00505	2	0	0	0	3	1	0	0	0	4	13	4	0	3	5	7	7	5	15	11	23	19	31	16	69	65	HMG_box
pfam05622	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	3	4	2	8	11	HOOK
pfam02793	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	9	7	5	4	9	8	30	30	HRM
pfam02218	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	7	8	3	19	13	HS1_rep
smart00120	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	3	0	5	8	12	13	72	72	HX
pfam00045	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	7	10	9	37	48	Hemopexin
smart00008	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	9	7	5	4	8	9	36	30	HormR
pfam06462	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	2	0	1	5	0	9	11	Hyd_WA
smart00409	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	672	395	1086	522	849	262	2055	1110	IG
smart00407	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	4	0	0	402	273	IGc1
smart00406	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	7	2	30	28	29	5	455	367	IGv
pfam00478	4	0	0	1	1	2	3	4	3	3	3	4	0	4	2	2	5	2	5	3	4	1	3	3	12	5	IMPDH
smart00187	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	2	2	7	2	3	6	13	14	INB
pfam01007	0	0	0	0	1	2	0	0	0	3	0	0	0	0	0	0	0	0	3	3	6	7	7	4	19	17	IRK
pfam02174	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	4	7	5	3	20	12	IRS
smart00191	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	7	4	2	14	18	28	66	79	Int_alpha
smart00558	5	0	1	1	0	3	2	3	3	4	19	10	0	4	4	4	4	3	14	11	13	10	14	8	35	33	JmjC
pfam02373	6	0	1	2	0	3	2	3	3	6	19	13	0	6	5	5	4	3	14	11	15	12	14	9	39	41	JmjC
pfam02149	3	0	0	0	0	0	0	0	0	1	2	6	0	1	1	1	2	2	5	3	4	2	3	2	11	6	KA1
smart00130	0	0	0	1	1	1	0	1	1	0	0	0	0	0	0	0	0	0	4	3	6	2	2	37	90	36	KR
pfam00051	0	0	0	1	1	1	0	1	1	0	0	0	0	0	0	0	0	0	3	2	6	2	2	35	89	36	Kringle
pfam02828	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	3	4	0	2	4	2	11	13	L27
smart00569	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	3	3	4	3	5	2	19	18	L27
pfam01273	0	0	0	0	0	0	0	0	0	1	2	0	0	0	0	0	0	0	5	6	0	0	0	2	17	11	LBP_BPI_CETP
pfam03815	0	0	0	6	6	1	0	0	0	0	0	0	0	0	2	1	0	0	0	0	0	0	0	22	13	10	LCCL
smart00603	0	0	0	7	6	1	0	0	0	0	0	0	0	0	2	1	1	1	0	0	0	0	0	23	13	10	LCCL
pfam04791	5	0	0	0	1	1	4	2	3	3	5	5	0	1	2	1	0	0	4	4	4	3	4	6	23	11	LMBR1
smart00082	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	9	16	42	25	29	14	91	78	LRRCT
smart00013	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	4	11	16	4	3	8	31	28	LRRNT
pfam01462	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	4	1	3	1	3	9	6	LRRNT
Species	Dd	Gt	Cm	Pf	Ch	Tg	Tb	Tc	Lm	Cr	At	Os	Ec	Sp	An	Nc	Sc	Cg	Ce	Cb	Am	Ag	Dm	Ci	Hs	Mm
smart00368	2	0	0	0	0	0	5	5	3	3	2	0	0	0	0	0	0	0	2	1	2	1	1	2	12	10	LRR_RI
smart00369	0	0	0	0	0	0	0	0	0	1	3	2	0	0	0	0	1	1	2	0	5	4	8	9	20	16	LRR_TYP
pfam00753	9	0	0	4	1	3	8	8	6	4	13	9	3	7	12	7	4	1	12	11	7	10	13	14	23	18	Lactamase_B
smart00282	0	0	0	0	0	0	0	2	0	0	0	0	0	0	0	0	0	0	47	41	107	76	85	31	199	159	LamG
smart00560	2	0	0	0	1	0	1	4	0	1	0	0	0	0	0	0	0	0	0	0	2	1	2	1	10	13	LamGL
smart00136	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	6	5	8	5	8	8	30	19	LamNT
pfam00053	2	0	0	0	0	0	2	0	0	0	0	0	0	0	0	0	0	0	40	32	49	27	51	42	135	88	Laminin_EGF
pfam00055	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	6	5	8	5	8	8	30	19	Laminin_N
pfam01299	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	5	2	9	9	Lamp
pfam00061	0	0	0	0	0	0	0	0	0	0	1	1	0	0	0	0	0	0	5	4	4	13	4	2	38	49	Lipocalin
pfam00629	0	0	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	2	3	5	3	9	52	42	26	MAM
smart00137	0	0	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0	0	8	8	3	3	9	55	42	26	MAM
pfam01284	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	7	4	2	3	2	4	25	17	MARVEL
smart00391	0	0	0	0	0	0	0	0	0	0	8	5	0	0	0	0	0	0	2	3	2	6	8	3	14	14	MBD
smart00561	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	9	15	15	9	16	9	59	44	MBT
pfam02820	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	10	14	9	16	9	55	41	MBT
pfam01853	2	0	0	1	2	2	4	6	4	1	2	0	2	2	3	3	3	3	5	4	6	5	7	4	12	8	MOZ_SAS
pfam00994	2	0	0	0	0	0	0	0	0	2	3	2	0	0	3	2	1	1	3	3	1	4	2	5	8	3	MoCF_biosynth
pfam06017	7	0	0	0	0	0	2	5	0	0	1	1	0	1	1	1	2	2	2	2	2	3	5	4	13	12	Myosin_tail_2
pfam00956	2	0	0	2	1	3	2	2	3	4	7	8	0	3	2	2	1	1	3	4	2	5	5	3	17	16	NAP
pfam04095	1	0	0	1	0	2	1	1	1	1	2	3	0	1	2	1	1	1	3	1	2	4	3	1	11	5	NAPRTase
smart00562	3	0	0	2	2	3	8	6	3	6	6	2	1	1	1	1	1	1	3	1	7	4	6	10	15	18	NDK
smart00227	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	3	4	1	4	3	96	62	NEBU
smart00539	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	8	8	4	2	3	5	19	12	NIDO
pfam01759	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	1	2	2	4	14	12	NTR
pfam00939	0	0	0	0	0	0	1	0	2	6	5	0	0	1	2	1	1	2	4	5	8	6	8	13	15	6	Na_sulph_symp
pfam06512	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	7	2	1	2	19	10	Na_trans_assoc
pfam03593	2	0	1	4	1	4	4	3	3	4	4	3	1	1	1	1	0	0	1	1	2	1	2	5	6	9	Nuclear_move
smart00284	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	2	0	1	2	8	26	13	OLF
pfam02191	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	2	0	1	2	8	24	13	OLF
pfam01237	11	0	0	2	2	2	0	2	0	4	13	2	0	6	5	5	7	6	7	4	6	6	8	6	24	17	Oxysterol_BP
pfam01089	3	0	0	1	1	2	2	2	1	1	2	1	0	1	4	1	1	1	2	2	4	5	5	2	10	5	P5CR
smart00085	0	0	0	0	0	0	0	0	0	0	5	1	0	0	0	0	0	0	2	1	4	6	6	6	13	17	PA2c
Species	Dd	Gt	Cm	Pf	Ch	Tg	Tb	Tc	Lm	Cr	At	Os	Ec	Sp	An	Nc	Sc	Cg	Ce	Cb	Am	Ag	Dm	Ci	Hs	Mm
pfam01569	5	0	0	0	0	1	3	2	2	0	7	6	1	3	6	4	6	7	9	6	0	6	12	6	20	21	PAP2
smart00285	4	0	0	0	0	0	0	0	0	0	12	8	0	2	2	2	4	3	10	7	5	6	9	4	25	15	PBD
smart00018	0	0	3	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	3	2	1	1	0	21	11	9	PD
smart00141	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	2	1	5	1	15	15	PDGF
smart00228	0	0	0	2	0	3	2	10	5	4	7	15	1	0	2	0	2	2	95	75	124	118	141	101	437	321	PDZ
pfam00595	0	0	0	1	0	2	0	1	2	2	0	4	0	0	0	0	1	0	72	58	93	94	114	72	343	277	PDZ
smart00233	63	0	0	3	5	7	19	26	13	4	18	12	2	17	14	13	15	14	61	48	66	67	109	81	372	324	PH
pfam00169	47	0	0	3	3	4	16	20	7	3	13	7	1	14	12	11	11	12	43	34	47	52	76	63	284	242	PH
smart00249	10	0	1	6	7	9	2	3	0	26	69	53	1	22	18	15	16	10	59	34	42	67	79	53	168	131	PHD
pfam00628	7	0	0	5	3	6	0	1	0	22	38	34	1	16	16	12	13	7	36	22	32	50	60	38	121	87	PHD
pfam05682	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	4	0	5	2	5	7	11	PHK_AB
smart00142	6	0	0	0	0	0	2	2	0	0	1	1	0	1	1	1	1	1	6	4	4	2	4	3	10	11	PI3K_C2
pfam00792	5	0	0	0	0	0	2	3	0	0	1	1	0	1	1	1	1	1	6	4	4	2	4	4	11	11	PI3K_C2
smart00144	4	0	0	0	0	0	0	2	1	0	0	0	0	0	0	0	0	0	2	2	2	1	2	2	9	8	PI3K_rbd
pfam00640	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	21	14	14	16	15	12	65	48	PID
smart00088	12	0	0	6	7	7	8	12	8	8	13	14	4	11	10	11	7	8	13	11	14	12	15	10	21	16	PINT
pfam01735	0	0	0	0	0	0	0	0	0	0	0	0	0	5	3	2	6	5	0	0	0	0	0	5	8	6	PLA2_B
smart00250	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	4	1	0	0	4	31	223	182	PLEC
smart00352	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	4	8	4	7	2	18	28	POU
smart00462	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	32	18	22	21	25	15	90	56	PTB
smart00310	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	8	7	5	3	20	12	PTBI
smart00159	1	0	0	0	1	0	0	2	0	1	0	2	0	0	0	0	0	0	1	1	3	4	4	4	18	20	PTX
pfam00855	2	0	0	0	0	1	2	3	1	1	12	8	0	3	1	0	2	2	2	1	2	2	12	11	52	29	PWWP
smart00293	3	0	0	0	0	1	2	3	2	3	12	8	0	3	1	1	2	2	2	1	2	3	12	12	52	31	PWWP
pfam00787	6	0	0	0	1	1	3	6	3	3	9	5	1	11	7	11	12	13	13	10	20	15	18	23	60	54	PX
smart00312	6	0	0	0	2	1	3	7	3	3	8	6	1	11	8	10	14	14	14	10	18	15	17	22	58	53	PX
pfam01562	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	5	4	9	5	48	57	Pep_M12B_propep
pfam03416	4	0	0	0	1	2	3	3	2	2	2	3	0	1	1	1	1	1	3	4	3	3	3	2	13	8	Peptidase_C54
pfam00413	0	0	0	0	0	0	0	0	0	0	5	1	0	0	0	0	0	0	4	4	2	3	4	7	33	31	Peptidase_M10
pfam03933	0	0	0	0	0	0	0	0	0	1	5	1	0	0	0	0	0	0	2	2	2	3	4	6	21	28	Peptidase_M10_N
pfam03036	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	3	4	4	2	8	13	Perilipin
pfam00068	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	2	1	0	1	1	6	13	15	Phospholip_A2_1
pfam00157	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	4	8	4	7	2	18	28	Pou
Species	Dd	Gt	Cm	Pf	Ch	Tg	Tb	Tc	Lm	Cr	At	Os	Ec	Sp	An	Nc	Sc	Cg	Ce	Cb	Am	Ag	Dm	Ci	Hs	Mm
pfam05044	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	3	2	4	2	10	4	Prox1
smart00393	3	0	0	0	0	1	5	3	2	0	6	4	0	2	4	4	4	2	2	3	0	2	6	6	11	16	R3H
pfam01424	1	0	0	0	0	0	1	2	1	0	2	1	0	3	1	3	3	2	2	3	0	2	6	4	11	15	R3H
pfam00788	3	0	0	0	0	0	0	0	0	0	0	0	0	2	2	2	1	1	24	14	23	18	22	7	52	41	RA
pfam00415	10	0	0	0	2	1	0	2	1	0	11	7	1	0	0	0	0	0	3	3	11	4	3	9	26	23	RCC1
pfam02257	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	1	1	2	1	2	0	3	3	4	11	12	RFX_DNA_binding
smart00315	11	0	0	0	0	0	0	0	0	0	1	0	0	2	4	5	5	3	25	18	12	14	21	29	63	48	RGS
pfam00554	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	7	3	5	3	13	18	RHD
smart00450	8	0	0	0	0	2	16	17	15	19	19	13	2	8	10	10	10	10	18	15	2	8	11	15	33	26	RHOD
smart00394	0	0	0	0	0	1	1	1	1	1	0	0	0	1	0	0	1	0	2	2	2	3	2	4	15	14	RIIa
smart00582	4	0	0	1	4	1	2	1	0	3	10	4	1	4	3	3	3	3	7	5	7	9	8	8	17	14	RPR
smart00361	8	0	0	4	4	6	6	2	2	5	23	12	3	4	7	8	3	7	13	14	12	7	20	13	40	38	RRM_1
smart00593	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	6	6	4	8	11	6	25	17	RUN
pfam02759	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	5	4	6	10	6	28	21	RUN
pfam04712	0	0	0	2	0	1	4	4	4	4	0	0	0	0	0	0	0	0	0	0	0	1	2	3	4	8	Radial_spoke
pfam00638	2	0	0	2	1	1	1	1	1	1	6	3	1	3	3	2	3	3	5	2	2	3	9	7	18	9	Ran_BP1
pfam00616	11	0	0	0	0	0	0	0	0	0	0	0	1	2	3	4	3	3	3	3	5	5	7	6	23	18	RasGAP
smart00323	12	0	0	0	0	1	0	0	0	0	0	0	0	2	3	4	4	3	4	3	6	5	10	7	33	31	RasGAP
smart00324	45	0	0	1	1	1	1	1	1	0	9	5	3	10	9	10	12	11	32	24	33	23	36	28	120	91	RhoGAP
pfam00620	44	0	0	1	1	1	1	1	1	0	9	5	3	10	7	8	11	9	31	23	33	22	35	28	112	89	RhoGAP
smart00325	48	0	1	0	0	0	0	0	0	0	0	0	1	8	5	5	5	4	34	21	39	27	53	30	117	92	RhoGEF
pfam00621	47	0	1	0	0	0	0	0	0	0	0	0	1	7	6	5	4	2	30	21	37	25	46	28	112	89	RhoGEF
pfam00581	4	0	0	0	0	2	9	12	7	14	15	8	2	8	7	6	10	7	10	9	1	7	8	9	30	24	Rhodanese
smart00454	9	0	0	1	1	0	4	4	0	5	7	5	0	4	5	5	1	1	36	25	20	31	40	29	136	125	SAM
pfam00536	4	0	0	0	1	0	4	0	0	1	5	2	0	4	4	3	1	1	24	19	12	19	28	19	91	91	SAM
smart00251	2	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	2	10	5	10	10	22	20	SAM_PNT
pfam02198	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	2	9	4	9	10	19	16	SAM_PNT
smart00258	0	0	0	0	0	0	0	0	0	2	0	0	0	0	0	0	0	0	4	3	2	1	1	3	9	14	SAND
pfam01342	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	4	3	2	1	1	3	9	14	SAND
smart00178	41	0	1	9	7	10	24	29	18	16	39	30	7	8	9	10	15	11	38	35	40	31	36	48	72	82	SAR
smart00200	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	8	5	0	0	0	1	30	18	SEA
pfam01390	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	8	4	0	0	0	1	21	17	SEA
smart00553	1	0	0	1	0	1	2	0	0	0	4	2	0	1	1	1	1	1	2	1	1	1	3	2	10	7	SEP
Species	Dd	Gt	Cm	Pf	Ch	Tg	Tb	Tc	Lm	Cr	At	Os	Ec	Sp	An	Nc	Sc	Cg	Ce	Cb	Am	Ag	Dm	Ci	Hs	Mm
smart00317	21	0	0	6	6	16	41	40	24	29	40	22	1	10	15	18	7	6	37	26	29	41	41	18	74	59	SET
pfam00017	9	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	50	32	49	34	46	48	149	149	SH2
smart00252	11	0	0	0	0	0	0	0	0	0	1	0	0	1	0	0	1	1	73	47	53	38	48	51	159	160	SH2
smart00326	31	0	0	0	0	0	6	10	6	0	3	3	0	21	25	24	28	26	105	88	131	86	179	103	360	332	SH3
pfam00018	25	0	0	0	0	0	5	10	5	0	2	3	0	21	18	21	27	22	73	74	110	74	148	87	309	285	SH3
smart00253	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	1	4	4	15	6	29	31	SOCS
pfam00622	8	0	0	1	0	3	13	17	8	8	7	1	0	3	2	3	3	3	15	32	35	17	25	16	117	80	SPRY
smart00449	8	1	0	1	0	4	19	23	8	8	7	1	0	3	3	3	4	3	15	33	36	18	25	17	120	84	SPRY
smart00202	0	0	0	2	2	0	0	0	0	49	0	0	0	0	0	0	0	0	4	4	8	8	16	9	155	109	SR
pfam00530	0	0	0	2	2	0	0	0	0	23	0	0	0	0	0	0	0	0	2	2	6	8	12	8	143	100	SRCR
pfam03365	1	0	0	0	0	0	1	2	1	1	1	4	1	2	1	1	2	2	1	1	0	3	4	3	15	6	STAG
pfam01369	6	0	0	0	1	5	5	4	4	2	7	6	1	6	4	4	5	4	6	5	12	5	10	6	23	18	Sec7
pfam01403	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	6	5	15	7	14	11	45	40	Sema
smart00630	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	9	7	16	7	15	12	51	44	Sema
pfam02750	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	1	3	4	4	0	4	6	Synapsin_C
smart00164	33	0	0	11	8	15	20	29	13	11	25	13	3	13	12	11	10	9	26	22	39	25	38	30	85	57	TBC
pfam00566	30	0	0	5	8	10	7	20	4	9	23	10	3	11	12	10	8	7	21	15	28	20	34	23	66	45	TBC
smart00706	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	0	4	0	5	4	TECPR
smart00510	1	0	0	2	1	1	1	2	1	2	6	4	1	1	2	1	1	2	1	1	3	3	3	2	10	8	TFS2M
pfam03299	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	4	1	2	1	2	1	10	7	TF_AP-2
smart00204	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	5	16	7	9	11	37	41	TGFB
pfam00019	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	5	16	7	9	11	40	44	TGF_beta
pfam00688	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	4	5	7	8	21	24	TGFb_propeptide
smart00460	4	0	0	0	0	0	0	0	0	1	2	0	0	3	2	3	2	2	2	2	4	4	6	6	15	16	TGc
pfam04201	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	1	0	7	0	13	7	TPD52
smart00210	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	7	2	11	10	4	9	43	43	TSPN
pfam05735	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	4	1	1	4	5	7	TSP_C
pfam02210	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	3	2	8	3	2	9	30	36	TSP_N
smart00211	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	11	11	12	12	10	11	30	35	TY
pfam00086	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	4	4	11	7	4	10	29	33	Thyroglobulin_1
pfam06309	2	0	0	2	0	3	4	6	4	1	5	8	0	1	2	1	1	2	3	2	0	3	1	2	14	8	Torsin
pfam00927	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	6	3	4	1	23	30	Transglut_C
pfam01841	4	0	0	0	0	0	0	0	0	0	1	0	0	1	1	1	1	1	1	1	1	3	5	4	15	16	Transglut_core
Species	Dd	Gt	Cm	Pf	Ch	Tg	Tb	Tc	Lm	Cr	At	Os	Ec	Sp	An	Nc	Sc	Cg	Ce	Cb	Am	Ag	Dm	Ci	Hs	Mm
pfam04906	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	3	4	1	3	6	0	16	11	Tweety
pfam00627	3	0	0	0	0	4	2	2	1	2	11	7	0	3	3	1	4	3	1	2	2	6	11	6	21	13	UBA
pfam00443	37	0	0	12	9	21	31	38	20	20	58	25	5	25	20	22	31	29	47	34	42	37	50	45	122	103	UCH
pfam01170	1	0	0	1	1	1	1	2	1	0	2	3	0	2	2	3	2	2	4	5	4	1	2	3	9	6	UPF0020
pfam03006	3	0	0	0	0	1	2	4	3	2	8	6	1	2	2	2	5	5	6	6	3	5	5	6	13	11	UPF0073
pfam04615	1	0	0	0	1	1	1	3	1	1	4	2	1	3	2	2	3	3	2	2	0	3	3	2	5	9	Utp14
pfam00790	1	0	0	0	0	0	1	2	1	2	8	7	0	5	4	4	4	3	6	5	4	5	5	4	17	16	VHS
smart00288	1	0	0	0	0	0	1	2	2	2	10	8	0	5	4	4	5	3	6	5	4	5	5	4	17	16	VHS
smart00167	8	0	0	0	1	1	1	3	1	0	2	3	1	2	2	3	2	2	4	4	2	2	3	3	13	16	VPS9
smart00214	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	7	6	15	5	33	37	VWC
pfam00093	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	8	11	11	6	34	34	VWC
smart00215	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	5	0	3	9	17	15	VWC_out
smart00217	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	3	2	5	2	4	0	8	7	WAP
pfam00400	186	4	5	41	30	56	113	104	70	135	227	192	26	130	165	118	87	89	154	138	214	220	240	199	430	395	WD40
smart00320	368	6	8	82	68	109	246	247	141	246	465	364	57	233	259	221	161	162	293	264	424	398	460	398	813	702	WD40
smart00456	5	0	0	4	1	5	13	17	7	9	11	7	1	10	7	8	8	7	38	27	50	41	43	31	119	83	WW
pfam00397	4	0	0	4	1	2	10	8	5	6	6	3	0	9	3	5	6	6	21	17	38	36	31	20	97	66	WW
smart00678	7	0	0	0	2	0	2	2	1	0	1	0	0	0	0	0	0	0	5	2	1	2	5	2	17	14	WWE
pfam02825	0	0	0	0	2	0	0	0	0	0	2	1	0	0	0	0	0	0	5	2	1	2	7	2	16	11	WWE
pfam04893	3	0	0	0	0	2	5	5	3	1	4	3	1	3	4	3	2	2	7	6	3	2	3	5	10	11	Yip1
smart00355	0	0	0	0	0	0	0	0	0	0	3	0	0	3	7	2	1	4	2	2	2	6	5	4	30	30	ZnF_C2H2
smart00451	6	0	0	2	2	3	0	0	2	1	15	2	0	4	5	4	5	5	6	3	6	13	16	8	41	28	ZnF_U1
smart00290	5	0	0	3	2	2	5	4	3	1	8	5	1	7	0	1	4	4	5	6	8	7	7	5	14	16	ZnF_UBP
smart00291	5	0	0	2	0	2	4	3	3	1	11	10	0	3	9	3	2	2	12	8	17	13	19	12	33	21	ZnF_ZZ
smart00014	5	0	0	0	0	1	4	2	2	0	5	6	1	4	5	3	6	7	7	6	0	6	9	5	23	22	acidPPc
pfam03455	2	0	0	0	0	0	0	0	0	0	1	0	0	1	1	1	0	0	6	5	7	9	10	3	35	25	dDENN
pfam00047	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	79	34	231	111	110	35	496	319	ig
pfam03456	5	0	0	0	0	0	0	0	0	0	0	0	0	1	1	1	0	0	6	5	6	8	9	4	33	28	uDENN
pfam00110	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	7	5	19	13	14	11	24	29	wnt
pfam00096	0	0	0	0	0	0	0	0	0	0	0	0	0	1	2	2	1	5	0	1	1	1	2	0	16	6	zf-C2H2
pfam01530	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	2	2	15	5	4	6	39	42	zf-C2HC
pfam02008	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	2	3	1	4	3	7	13	zf-CXXC
pfam00641	0	0	0	0	0	0	0	2	1	0	2	0	0	1	2	1	2	2	0	1	0	0	4	0	17	10	zf-RanBP
Species	Dd	Gt	Cm	Pf	Ch	Tg	Tb	Tc	Lm	Cr	At	Os	Ec	Sp	An	Nc	Sc	Cg	Ce	Cb	Am	Ag	Dm	Ci	Hs	Mm
pfam02148	5	0	0	2	1	1	5	4	3	1	7	5	1	4	1	0	3	3	5	6	7	6	6	5	13	15	zf-UBP